More than 300 homologs were found in PanDaTox collection
for query gene Arth_2840 on replicon NC_008541
Organism: Arthrobacter sp. FB24



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_008541  Arth_2840  binding-protein-dependent transport systems inner membrane component  100 
 
 
248 aa  478  1e-134  Arthrobacter sp. FB24  Bacteria  decreased coverage  0.00306406  n/a   
 
 
-
 
NC_011886  Achl_2555  binding-protein-dependent transport systems inner membrane component  89.11 
 
 
248 aa  394  1e-109  Arthrobacter chlorophenolicus A6  Bacteria  n/a    hitchhiker  0.0000000304534 
 
 
-
 
NC_013172  Bfae_30020  ABC-type proline/glycine betaine transport system, permease component  56.16 
 
 
223 aa  201  9.999999999999999e-51  Brachybacterium faecium DSM 4810  Bacteria  normal  0.115362  n/a   
 
 
-
 
NC_013093  Amir_6269  binding-protein-dependent transport systems inner membrane component  54.5 
 
 
243 aa  175  6e-43  Actinosynnema mirum DSM 43827  Bacteria  normal  n/a   
 
 
-
 
NC_009338  Mflv_1210  binding-protein-dependent transport systems inner membrane component  54.12 
 
 
257 aa  173  1.9999999999999998e-42  Mycobacterium gilvum PYR-GCK  Bacteria  normal  normal 
 
 
-
 
NC_013169  Ksed_26240  ABC-type proline/glycine betaine transport system, permease component  43.35 
 
 
230 aa  171  7.999999999999999e-42  Kytococcus sedentarius DSM 20547  Bacteria  normal  0.408698  normal  0.833764 
 
 
-
 
NC_009077  Mjls_5345  binding-protein-dependent transport systems inner membrane component  46.01 
 
 
264 aa  170  2e-41  Mycobacterium sp. JLS  Bacteria  normal  0.214986  normal 
 
 
-
 
NC_008705  Mkms_5052  binding-protein-dependent transport systems inner membrane component  46.01 
 
 
264 aa  170  2e-41  Mycobacterium sp. KMS  Bacteria  normal  normal 
 
 
-
 
NC_008146  Mmcs_4964  binding-protein-dependent transport systems inner membrane component  46.01 
 
 
264 aa  170  2e-41  Mycobacterium sp. MCS  Bacteria  normal  0.517846  n/a   
 
 
-
 
NC_008726  Mvan_5598  binding-protein-dependent transport systems inner membrane component  53.09 
 
 
264 aa  168  6e-41  Mycobacterium vanbaalenii PYR-1  Bacteria  normal  normal 
 
 
-
 
NC_014210  Ndas_0399  binding-protein-dependent transport systems inner membrane component  46.05 
 
 
225 aa  168  7e-41  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  normal 
 
 
-
 
NC_011989  Avi_0503  ABC transporter  48.1 
 
 
225 aa  168  9e-41  Agrobacterium vitis S4  Bacteria  normal  n/a   
 
 
-
 
NC_009664  Krad_1292  binding-protein-dependent transport systems inner membrane component  53.37 
 
 
251 aa  166  2.9999999999999998e-40  Kineococcus radiotolerans SRS30216  Bacteria  normal  normal 
 
 
-
 
NC_013595  Sros_8179  proline/glycine betaine ABC transporter  47.49 
 
 
223 aa  165  5.9999999999999996e-40  Streptosporangium roseum DSM 43021  Bacteria  normal  normal 
 
 
-
 
NC_013510  Tcur_3634  binding-protein-dependent transport systems inner membrane component  42.54 
 
 
229 aa  164  2.0000000000000002e-39  Thermomonospora curvata DSM 43183  Bacteria  normal  0.737383  n/a   
 
 
-
 
NC_009565  TBFG_13788  osmoprotectant (glycine betaine/carnitine/choline/L-proline) transport system permease protein proZ  54.59 
 
 
239 aa  162  6e-39  Mycobacterium tuberculosis F11  Bacteria  normal  normal  0.991425 
 
 
-
 
NC_013174  Jden_2260  binding-protein-dependent transport systems inner membrane component  47.77 
 
 
227 aa  155  8e-37  Jonesia denitrificans DSM 20603  Bacteria  normal  normal  0.360102 
 
 
-
 
NC_013131  Caci_3085  binding-protein-dependent transport systems inner membrane component  42.59 
 
 
225 aa  150  2e-35  Catenulispora acidiphila DSM 44928  Bacteria  normal  0.416296  normal  0.12861 
 
 
-
 
NC_013421  Pecwa_4555  binding-protein-dependent transport systems inner membrane component  42.44 
 
 
226 aa  139  3.9999999999999997e-32  Pectobacterium wasabiae WPP163  Bacteria  normal  n/a   
 
 
-
 
NC_013235  Namu_1404  binding-protein-dependent transport systems inner membrane component  44.78 
 
 
258 aa  137  1e-31  Nakamurella multipartita DSM 44233  Bacteria  normal  normal  0.848892 
 
 
-
 
NC_013521  Sked_37580  ABC-type proline/glycine betaine transport system, permease component  40.28 
 
 
228 aa  132  5e-30  Sanguibacter keddieii DSM 10542  Bacteria  normal  normal 
 
 
-
 
NC_009380  Strop_4289  binding-protein-dependent transport systems inner membrane component  43.13 
 
 
244 aa  129  6e-29  Salinispora tropica CNB-440  Bacteria  normal  0.729168  normal  0.839045 
 
 
-
 
NC_009632  SaurJH1_2522  binding-protein-dependent transport systems inner membrane component  34.48 
 
 
211 aa  122  4e-27  Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  0.241712  n/a   
 
 
-
 
NC_009487  SaurJH9_2474  binding-protein-dependent transport systems inner membrane component  34.48 
 
 
211 aa  122  4e-27  Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  0.13842  n/a   
 
 
-
 
NC_009953  Sare_4724  binding-protein-dependent transport systems inner membrane component  41.55 
 
 
244 aa  121  9e-27  Salinispora arenicola CNS-205  Bacteria  normal  decreased coverage  0.0000283909 
 
 
-
 
NC_013947  Snas_1035  binding-protein-dependent transport systems inner membrane component  37.38 
 
 
236 aa  121  9.999999999999999e-27  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  normal  0.163683 
 
 
-
 
NC_002976  SERP2030  amino acid ABC transporter, permease protein  31.47 
 
 
211 aa  119  3.9999999999999996e-26  Staphylococcus epidermidis RP62A  Bacteria  normal  0.207242  n/a   
 
 
-
 
NC_014151  Cfla_1339  binding-protein-dependent transport systems inner membrane component  39.23 
 
 
255 aa  118  9e-26  Cellulomonas flavigena DSM 20109  Bacteria  normal  0.889629  hitchhiker  0.000819014 
 
 
-
 
NC_013739  Cwoe_3263  binding-protein-dependent transport systems inner membrane component  37.5 
 
 
229 aa  115  6.9999999999999995e-25  Conexibacter woesei DSM 14684  Bacteria  normal  normal  0.0142604 
 
 
-
 
NC_009621  Smed_5106  binding-protein-dependent transport systems inner membrane component  34.56 
 
 
220 aa  114  1.0000000000000001e-24  Sinorhizobium medicae WSM419  Bacteria  normal  0.485727  normal  0.10095 
 
 
-
 
NC_008254  Meso_2980  binding-protein-dependent transport systems inner membrane component  33.01 
 
 
211 aa  114  1.0000000000000001e-24  Chelativorans sp. BNC1  Bacteria  normal  n/a   
 
 
-
 
NC_012669  Bcav_2670  binding-protein-dependent transport systems inner membrane component  36.92 
 
 
230 aa  114  1.0000000000000001e-24  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.538253  normal  0.0824918 
 
 
-
 
NC_002976  SERP2357  amino acid ABC transporter, permease protein  32.12 
 
 
211 aa  114  2.0000000000000002e-24  Staphylococcus epidermidis RP62A  Bacteria  normal  n/a   
 
 
-
 
NC_013757  Gobs_0624  binding-protein-dependent transport systems inner membrane component  43.83 
 
 
243 aa  114  2.0000000000000002e-24  Geodermatophilus obscurus DSM 43160  Bacteria  normal  n/a   
 
 
-
 
NC_013730  Slin_0317  binding-protein-dependent transport systems inner membrane component  34.62 
 
 
519 aa  114  2.0000000000000002e-24  Spirosoma linguale DSM 74  Bacteria  normal  normal  0.417886 
 
 
-
 
NC_009621  Smed_5104  binding-protein-dependent transport systems inner membrane component  35.11 
 
 
251 aa  111  1.0000000000000001e-23  Sinorhizobium medicae WSM419  Bacteria  normal  normal  0.245299 
 
 
-
 
NC_010003  Pmob_1127  binding-protein-dependent transport systems inner membrane component  30.62 
 
 
216 aa  110  2.0000000000000002e-23  Petrotoga mobilis SJ95  Bacteria  normal  0.721959  n/a   
 
 
-
 
NC_009767  Rcas_2528  binding-protein-dependent transport systems inner membrane component  42.62 
 
 
217 aa  108  9.000000000000001e-23  Roseiflexus castenholzii DSM 13941  Bacteria  normal  hitchhiker  0.00802547 
 
 
-
 
NC_012793  GWCH70_0296  binding-protein-dependent transport systems inner membrane component  36.07 
 
 
211 aa  108  1e-22  Geobacillus sp. WCH70  Bacteria  normal  0.4946  n/a   
 
 
-
 
NC_008786  Veis_2246  binding-protein-dependent transport systems inner membrane component  38.5 
 
 
243 aa  107  2e-22  Verminephrobacter eiseniae EF01-2  Bacteria  normal  0.0455559  normal 
 
 
-
 
NC_010320  Teth514_1202  binding-protein-dependent transport systems inner membrane component  30.69 
 
 
212 aa  106  3e-22  Thermoanaerobacter sp. X514  Bacteria  normal  n/a   
 
 
-
 
NC_008786  Veis_2912  binding-protein-dependent transport systems inner membrane component  35.08 
 
 
250 aa  106  3e-22  Verminephrobacter eiseniae EF01-2  Bacteria  normal  normal  0.105441 
 
 
-
 
NC_007963  Csal_2355  binding-protein-dependent transport systems inner membrane component  35.68 
 
 
243 aa  105  5e-22  Chromohalobacter salexigens DSM 3043  Bacteria  normal  n/a   
 
 
-
 
NC_004116  SAG0243  amino acid ABC transporter, permease protein  34.07 
 
 
211 aa  105  6e-22  Streptococcus agalactiae 2603V/R  Bacteria  normal  n/a   
 
 
-
 
NC_009523  RoseRS_1817  binding-protein-dependent transport systems inner membrane component  42.37 
 
 
217 aa  105  9e-22  Roseiflexus sp. RS-1  Bacteria  normal  normal  0.0299279 
 
 
-
 
NC_013411  GYMC61_1174  binding-protein-dependent transport systems inner membrane component  36.07 
 
 
209 aa  103  2e-21  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_013037  Dfer_1250  binding-protein-dependent transport systems inner membrane component  35.19 
 
 
525 aa  103  2e-21  Dyadobacter fermentans DSM 18053  Bacteria  normal  0.615651  normal  0.522042 
 
 
-
 
NC_009523  RoseRS_1814  binding-protein-dependent transport systems inner membrane component  36.7 
 
 
213 aa  103  4e-21  Roseiflexus sp. RS-1  Bacteria  normal  0.518824  normal  0.0107204 
 
 
-
 
NC_011830  Dhaf_2803  binding-protein-dependent transport systems inner membrane component  35.9 
 
 
218 aa  102  6e-21  Desulfitobacterium hafniense DCB-2  Bacteria  hitchhiker  0.000000135531  n/a   
 
 
-
 
NC_012803  Mlut_15730  ABC-type proline/glycine betaine transport system, permease component  37.31 
 
 
251 aa  102  6e-21  Micrococcus luteus NCTC 2665  Bacteria  normal  n/a   
 
 
-
 
NC_007948  Bpro_1156  binding-protein-dependent transport systems inner membrane component  37.63 
 
 
207 aa  102  6e-21  Polaromonas sp. JS666  Bacteria  normal  normal 
 
 
-
 
NC_013517  Sterm_1515  Substrate-binding region of ABC-type glycine betaine transport system  28.73 
 
 
526 aa  102  7e-21  Sebaldella termitidis ATCC 33386  Bacteria  normal  0.0692577  n/a   
 
 
-
 
NC_010003  Pmob_1125  binding-protein-dependent transport systems inner membrane component  29.38 
 
 
218 aa  101  1e-20  Petrotoga mobilis SJ95  Bacteria  normal  n/a   
 
 
-
 
NC_013517  Sterm_3032  Substrate-binding region of ABC-type glycine betaine transport system  29.19 
 
 
531 aa  101  1e-20  Sebaldella termitidis ATCC 33386  Bacteria  normal  0.367999  n/a   
 
 
-
 
NC_013132  Cpin_4963  binding-protein-dependent transport systems inner membrane component  36.51 
 
 
522 aa  101  1e-20  Chitinophaga pinensis DSM 2588  Bacteria  normal  0.0875398  normal  0.252786 
 
 
-
 
NC_007948  Bpro_1155  binding-protein-dependent transport systems inner membrane component  37.84 
 
 
213 aa  100  2e-20  Polaromonas sp. JS666  Bacteria  normal  normal 
 
 
-
 
NC_013204  Elen_0084  Substrate-binding region of ABC-type glycine betaine transport system  31.58 
 
 
528 aa  100  2e-20  Eggerthella lenta DSM 2243  Bacteria  normal  0.689632  normal 
 
 
-
 
NC_002976  SERP0386  ABC transporter, permease protein  36.96 
 
 
504 aa  99.8  3e-20  Staphylococcus epidermidis RP62A  Bacteria  normal  n/a   
 
 
-
 
NC_009632  SaurJH1_0763  substrate-binding region of ABC-type glycine betaine transport system  38.04 
 
 
504 aa  99.8  4e-20  Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  0.458546  n/a   
 
 
-
 
NC_009487  SaurJH9_0746  substrate-binding region of ABC-type glycine betaine transport system  38.04 
 
 
504 aa  99.8  4e-20  Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  n/a   
 
 
-
 
NC_009767  Rcas_2531  binding-protein-dependent transport systems inner membrane component  37.5 
 
 
213 aa  99.4  5e-20  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.41546  hitchhiker  0.00151664 
 
 
-
 
NC_013745  Htur_4755  binding-protein-dependent transport systems inner membrane component  32.43 
 
 
224 aa  97.8  1e-19  Haloterrigena turkmenica DSM 5511  Archaea  normal  n/a   
 
 
-
 
NC_009972  Haur_0352  binding-protein-dependent transport systems inner membrane component  33.16 
 
 
212 aa  98.2  1e-19  Herpetosiphon aurantiacus ATCC 23779  Bacteria  hitchhiker  0.00133912  n/a   
 
 
-
 
NC_008148  Rxyl_0984  binding-protein-dependent transport systems inner membrane component  38.79 
 
 
236 aa  97.1  2e-19  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  0.660466  n/a   
 
 
-
 
NC_011898  Ccel_3333  Substrate-binding region of ABC-type glycine betaine transport system  27.17 
 
 
524 aa  96.7  3e-19  Clostridium cellulolyticum H10  Bacteria  hitchhiker  0.0000937167  n/a   
 
 
-
 
NC_008148  Rxyl_0578  binding-protein-dependent transport systems inner membrane component  38.79 
 
 
235 aa  96.7  3e-19  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  0.0139749  n/a   
 
 
-
 
NC_010001  Cphy_0119  substrate-binding region of ABC-type glycine betaine transport system  29.94 
 
 
523 aa  96.7  3e-19  Clostridium phytofermentans ISDg  Bacteria  hitchhiker  0.000124345  n/a   
 
 
-
 
NC_013223  Dret_0769  binding-protein-dependent transport systems inner membrane component  32.38 
 
 
245 aa  95.9  5e-19  Desulfohalobium retbaense DSM 5692  Bacteria  normal  normal 
 
 
-
 
NC_008148  Rxyl_0983  binding-protein-dependent transport systems inner membrane component  35.05 
 
 
217 aa  95.5  6e-19  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  0.762927  n/a   
 
 
-
 
NC_009727  CBUD_1923  glycine betaine transport system permease protein  31.68 
 
 
526 aa  95.5  7e-19  Coxiella burnetii Dugway 5J108-111  Bacteria  normal  n/a   
 
 
-
 
NC_008527  LACR_0914  choline ABC transporter permease and substrate binding protein  28.19 
 
 
500 aa  94.7  1e-18  Lactococcus lactis subsp. cremoris SK11  Bacteria  normal  0.222381  n/a   
 
 
-
 
NC_007963  Csal_2353  binding-protein-dependent transport systems inner membrane component  32.64 
 
 
220 aa  94.4  2e-18  Chromohalobacter salexigens DSM 3043  Bacteria  normal  n/a   
 
 
-
 
NC_010117  COXBURSA331_A0267  quaternary amine ABC transporter periplasmic substrate-binding protein  31.19 
 
 
526 aa  93.2  4e-18  Coxiella burnetii RSA 331  Bacteria  normal  n/a   
 
 
-
 
NC_009380  Strop_1634  binding-protein-dependent transport systems inner membrane component  37.25 
 
 
261 aa  91.7  9e-18  Salinispora tropica CNB-440  Bacteria  normal  0.649793  normal  0.788807 
 
 
-
 
NC_011772  BCG9842_B3062  glycine betaine/L-proline ABC transporter, permease and substrate-binding protein  34.59 
 
 
503 aa  90.9  2e-17  Bacillus cereus G9842  Bacteria  normal  normal 
 
 
-
 
NC_007963  Csal_2944  binding-protein-dependent transport systems inner membrane component  34.52 
 
 
400 aa  90.9  2e-17  Chromohalobacter salexigens DSM 3043  Bacteria  normal  0.543286  n/a   
 
 
-
 
NC_009972  Haur_0349  binding-protein-dependent transport systems inner membrane component  35.98 
 
 
217 aa  89.7  4e-17  Herpetosiphon aurantiacus ATCC 23779  Bacteria  hitchhiker  0.0000441273  n/a   
 
 
-
 
NC_011725  BCB4264_A2263  glycine betaine/L-proline ABC transporter, permease and substrate-binding protein  34.05 
 
 
503 aa  89.7  4e-17  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_008148  Rxyl_0579  binding-protein-dependent transport systems inner membrane component  34.9 
 
 
217 aa  89.7  4e-17  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  0.584474  n/a   
 
 
-
 
NC_003909  BCE_2314  glycine betaine/L-proline ABC transporter, permease protein, putative  34.59 
 
 
503 aa  89  6e-17  Bacillus cereus ATCC 10987  Bacteria  normal  0.0653078  n/a   
 
 
-
 
NC_013745  Htur_4757  binding-protein-dependent transport systems inner membrane component  29.02 
 
 
228 aa  89  6e-17  Haloterrigena turkmenica DSM 5511  Archaea  normal  n/a   
 
 
-
 
NC_013457  VEA_001529  probable inner-membrane permease  31.38 
 
 
199 aa  89  7e-17  Vibrio sp. Ex25  Bacteria  normal  0.90895  n/a   
 
 
-
 
NC_010184  BcerKBAB4_2100  substrate-binding region of ABC-type glycine betaine transport system  36.17 
 
 
503 aa  89  7e-17  Bacillus weihenstephanensis KBAB4  Bacteria  normal  0.0700074  n/a   
 
 
-
 
NC_009953  Sare_1621  binding-protein-dependent transport systems inner membrane component  34.03 
 
 
261 aa  88.2  1e-16  Salinispora arenicola CNS-205  Bacteria  normal  normal 
 
 
-
 
NC_010159  YpAngola_A1330  quaternary amine ABC transporter permease  30.14 
 
 
384 aa  87.8  1e-16  Yersinia pestis Angola  Bacteria  normal  normal 
 
 
-
 
NC_008786  Veis_2244  binding-protein-dependent transport systems inner membrane component  31.6 
 
 
229 aa  88.2  1e-16  Verminephrobacter eiseniae EF01-2  Bacteria  normal  0.259993  normal 
 
 
-
 
NC_007973  Rmet_1598  substrate-binding region of ABC-type glycine betaine transport system  33.52 
 
 
516 aa  88.2  1e-16  Cupriavidus metallidurans CH34  Bacteria  normal  0.144217  normal 
 
 
-
 
NC_010465  YPK_2864  binding-protein-dependent transport systems inner membrane component  30.14 
 
 
384 aa  87.8  1e-16  Yersinia pseudotuberculosis YPIII  Bacteria  normal  n/a   
 
 
-
 
NC_013457  VEA_001531  putative ABC transporter permease  34.65 
 
 
244 aa  88.2  1e-16  Vibrio sp. Ex25  Bacteria  normal  n/a   
 
 
-
 
NC_008347  Mmar10_1070  substrate-binding region of ABC-type glycine betaine transport system  31.98 
 
 
525 aa  87.8  1e-16  Maricaulis maris MCS10  Bacteria  normal  0.019749  normal 
 
 
-
 
NC_005945  BAS2126  glycine betaine/L-proline ABC transporter permease  33.51 
 
 
503 aa  87.8  2e-16  Bacillus anthracis str. Sterne  Bacteria  normal  0.887969  n/a   
 
 
-
 
NC_005957  BT9727_2064  glycine betaine/choline ABC transporter, ATP-binding protein  33.51 
 
 
503 aa  87.8  2e-16  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  0.508054  n/a   
 
 
-
 
NC_006274  BCZK2060  glycine betaine/choline ABC transporter, ATP-binding protein  33.51 
 
 
503 aa  87.8  2e-16  Bacillus cereus E33L  Bacteria  normal  n/a   
 
 
-
 
NC_011773  BCAH820_2306  glycine betaine/L-proline ABC transporter, permease and substrate-binding protein  33.51 
 
 
503 aa  87.4  2e-16  Bacillus cereus AH820  Bacteria  n/a    normal  0.816481 
 
 
-
 
NC_009708  YpsIP31758_2785  quaternary amine ABC transporter permease  30.14 
 
 
384 aa  87.8  2e-16  Yersinia pseudotuberculosis IP 31758  Bacteria  normal  n/a   
 
 
-
 
NC_007530  GBAA_2280  glycine betaine/L-proline ABC transporter permease protein  33.51 
 
 
503 aa  87.8  2e-16  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  0.578491  n/a   
 
 
-
 
NC_013530  Xcel_1079  binding-protein-dependent transport systems inner membrane component  36.49 
 
 
225 aa  87.4  2e-16  Xylanimonas cellulosilytica DSM 15894  Bacteria  normal  0.663107  n/a   
 
 
-
 
NC_011658  BCAH187_A2390  glycine betaine/L-proline ABC transporter, permease and substrate-binding protein  33.7 
 
 
503 aa  86.7  3e-16  Bacillus cereus AH187  Bacteria  normal  0.114171  n/a   
 
 
-
 
NC_007948  Bpro_3625  binding-protein-dependent transport systems inner membrane component  31.5 
 
 
383 aa  86.7  3e-16  Polaromonas sp. JS666  Bacteria  normal  normal 
 
 
-
 
NC_009436  Ent638_1924  binding-protein-dependent transport systems inner membrane component  32.26 
 
 
245 aa  86.7  3e-16  Enterobacter sp. 638  Bacteria  normal  normal 
 
 
-
 
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