More than 300 homologs were found in PanDaTox collection
for query gene EcolC_2314 on replicon NC_010468
Organism: Escherichia coli ATCC 8739



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
CP001509  ECD_01288  predicted sugar transporter subunit: membrane component of ABC superfamily  100 
 
 
293 aa  582  1.0000000000000001e-165  Escherichia coli BL21(DE3)  Bacteria  normal  n/a   
 
 
-
 
NC_012892  B21_01299  hypothetical protein  100 
 
 
293 aa  582  1.0000000000000001e-165  Escherichia coli BL21  Bacteria  normal  n/a   
 
 
-
 
NC_010468  EcolC_2314  binding-protein-dependent transport systems inner membrane component  100 
 
 
293 aa  582  1.0000000000000001e-165  Escherichia coli ATCC 8739  Bacteria  normal  0.71913  normal 
 
 
-
 
NC_009800  EcHS_A1426  putative sugar ABC transporter, permease protein  100 
 
 
293 aa  582  1.0000000000000001e-165  Escherichia coli HS  Bacteria  normal  n/a   
 
 
-
 
CP001637  EcDH1_2335  binding-protein-dependent transport systems inner membrane component  99.66 
 
 
293 aa  579  1e-164  Escherichia coli DH1  Bacteria  normal  0.102296  n/a   
 
 
-
 
NC_010498  EcSMS35_1811  putative sugar ABC transporter, permease protein  99.66 
 
 
293 aa  579  1e-164  Escherichia coli SMS-3-5  Bacteria  normal  normal 
 
 
-
 
NC_011353  ECH74115_1956  putative sugar ABC transporter, permease protein  99.32 
 
 
293 aa  578  1e-164  Escherichia coli O157:H7 str. EC4115  Bacteria  normal  0.798746  normal 
 
 
-
 
NC_009801  EcE24377A_1521  putative sugar ABC transporter, permease protein  99.66 
 
 
293 aa  579  1e-164  Escherichia coli E24377A  Bacteria  normal  n/a   
 
 
-
 
NC_009436  Ent638_2163  binding-protein-dependent transport systems inner membrane component  91.32 
 
 
291 aa  515  1.0000000000000001e-145  Enterobacter sp. 638  Bacteria  normal  normal  0.270526 
 
 
-
 
NC_013517  Sterm_1525  binding-protein-dependent transport systems inner membrane component  61.75 
 
 
292 aa  359  3e-98  Sebaldella termitidis ATCC 33386  Bacteria  normal  n/a   
 
 
-
 
NC_010003  Pmob_0073  binding-protein-dependent transport systems inner membrane component  37.72 
 
 
294 aa  206  3e-52  Petrotoga mobilis SJ95  Bacteria  normal  n/a   
 
 
-
 
NC_014213  Mesil_3421  binding-protein-dependent transport systems inner membrane component  34.64 
 
 
307 aa  165  9e-40  Meiothermus silvanus DSM 9946  Bacteria  normal  0.556907  normal 
 
 
-
 
NC_014213  Mesil_3227  extracellular solute-binding protein family 1  34.64 
 
 
307 aa  165  9e-40  Meiothermus silvanus DSM 9946  Bacteria  decreased coverage  0.00159401  normal  0.987884 
 
 
-
 
NC_011899  Hore_00790  binding-protein-dependent transport systems inner membrane component  36.36 
 
 
262 aa  161  1e-38  Halothermothrix orenii H 168  Bacteria  normal  0.772214  n/a   
 
 
-
 
NC_013525  Tter_0398  binding-protein-dependent transport systems inner membrane component  33.21 
 
 
312 aa  158  8e-38  Thermobaculum terrenum ATCC BAA-798  Bacteria  n/a    n/a   
 
 
-
 
NC_013739  Cwoe_0172  binding-protein-dependent transport systems inner membrane component  35.25 
 
 
324 aa  155  7e-37  Conexibacter woesei DSM 14684  Bacteria  normal  normal 
 
 
-
 
NC_010003  Pmob_0028  binding-protein-dependent transport systems inner membrane component  32.76 
 
 
300 aa  154  1e-36  Petrotoga mobilis SJ95  Bacteria  unclonable  0.0000000378352  n/a   
 
 
-
 
NC_011899  Hore_20460  binding-protein-dependent transport systems inner membrane component  33.56 
 
 
321 aa  152  8.999999999999999e-36  Halothermothrix orenii H 168  Bacteria  hitchhiker  0.00000522199  n/a   
 
 
-
 
NC_012848  Rleg_5199  binding-protein-dependent transport systems inner membrane component  32.98 
 
 
312 aa  151  1e-35  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  normal  0.0867066 
 
 
-
 
NC_009667  Oant_0362  binding-protein-dependent transport systems inner membrane component  31.71 
 
 
312 aa  151  1e-35  Ochrobactrum anthropi ATCC 49188  Bacteria  normal  0.541424  n/a   
 
 
-
 
NC_007802  Jann_1284  binding-protein-dependent transport systems inner membrane component  35.5 
 
 
414 aa  150  3e-35  Jannaschia sp. CCS1  Bacteria  hitchhiker  0.00128894  normal 
 
 
-
 
NC_008786  Veis_1880  binding-protein-dependent transport systems inner membrane component  34.44 
 
 
286 aa  150  3e-35  Verminephrobacter eiseniae EF01-2  Bacteria  normal  0.262739  normal  0.333569 
 
 
-
 
NC_011729  PCC7424_1896  binding-protein-dependent transport systems inner membrane component  31.96 
 
 
296 aa  150  3e-35  Cyanothece sp. PCC 7424  Bacteria  n/a    hitchhiker  1.0543799999999999e-20 
 
 
-
 
NC_011368  Rleg2_5469  binding-protein-dependent transport systems inner membrane component  32.98 
 
 
313 aa  149  4e-35  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  normal  0.394829 
 
 
-
 
NC_009832  Spro_2296  binding-protein-dependent transport systems inner membrane component  34.8 
 
 
304 aa  149  8e-35  Serratia proteamaculans 568  Bacteria  normal  0.44429  normal 
 
 
-
 
NC_009939  Dgeo_2918  ABC-type sugar transport system, permease component  35.53 
 
 
305 aa  146  4.0000000000000006e-34  Deinococcus geothermalis DSM 11300  Bacteria  n/a    n/a   
 
 
-
 
NC_011899  Hore_19880  binding-protein-dependent transport systems inner membrane component  31.19 
 
 
323 aa  145  6e-34  Halothermothrix orenii H 168  Bacteria  normal  n/a   
 
 
-
 
NC_013202  Hmuk_0943  binding-protein-dependent transport systems inner membrane component  34.42 
 
 
312 aa  144  2e-33  Halomicrobium mukohataei DSM 12286  Archaea  normal  normal  0.301949 
 
 
-
 
NC_009620  Smed_3590  binding-protein-dependent transport systems inner membrane component  31.23 
 
 
301 aa  144  2e-33  Sinorhizobium medicae WSM419  Bacteria  normal  0.657903  normal 
 
 
-
 
NC_012669  Bcav_0321  binding-protein-dependent transport systems inner membrane component  34.31 
 
 
316 aa  141  1.9999999999999998e-32  Beutenbergia cavernae DSM 12333  Bacteria  normal  normal 
 
 
-
 
NC_011071  Smal_2682  binding-protein-dependent transport systems inner membrane component  34.4 
 
 
293 aa  140  1.9999999999999998e-32  Stenotrophomonas maltophilia R551-3  Bacteria  normal  0.990678  normal 
 
 
-
 
NC_007604  Synpcc7942_0949  permease protein of sugar ABC transporter  31.93 
 
 
292 aa  140  1.9999999999999998e-32  Synechococcus elongatus PCC 7942  Bacteria  normal  0.688345  normal 
 
 
-
 
NC_010513  Xfasm12_1606  ABC transporter sugar permease  31.82 
 
 
293 aa  140  1.9999999999999998e-32  Xylella fastidiosa M12  Bacteria  normal  n/a   
 
 
-
 
NC_009668  Oant_2941  binding-protein-dependent transport systems inner membrane component  30.53 
 
 
320 aa  141  1.9999999999999998e-32  Ochrobactrum anthropi ATCC 49188  Bacteria  normal  0.974377  n/a   
 
 
-
 
NC_012669  Bcav_0307  binding-protein-dependent transport systems inner membrane component  32.67 
 
 
322 aa  140  3e-32  Beutenbergia cavernae DSM 12333  Bacteria  normal  normal 
 
 
-
 
NC_010577  XfasM23_1549  binding-protein-dependent transport systems inner membrane component  31.47 
 
 
293 aa  139  3.9999999999999997e-32  Xylella fastidiosa M23  Bacteria  normal  0.563461  n/a   
 
 
-
 
NC_007963  Csal_0259  binding-protein-dependent transport systems inner membrane component  31.44 
 
 
324 aa  139  4.999999999999999e-32  Chromohalobacter salexigens DSM 3043  Bacteria  normal  n/a   
 
 
-
 
NC_009718  Fnod_0449  binding-protein-dependent transport systems inner membrane component  31.79 
 
 
295 aa  139  4.999999999999999e-32  Fervidobacterium nodosum Rt17-B1  Bacteria  normal  0.982578  n/a   
 
 
-
 
NC_009832  Spro_2525  binding-protein-dependent transport systems inner membrane component  32.88 
 
 
330 aa  139  4.999999999999999e-32  Serratia proteamaculans 568  Bacteria  normal  normal 
 
 
-
 
NC_014211  Ndas_5073  binding-protein-dependent transport systems inner membrane component  35.25 
 
 
330 aa  139  6e-32  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  normal 
 
 
-
 
NC_012791  Vapar_3349  binding-protein-dependent transport systems inner membrane component  32.02 
 
 
291 aa  137  2e-31  Variovorax paradoxus S110  Bacteria  normal  0.230089  n/a   
 
 
-
 
NC_013093  Amir_0349  binding-protein-dependent transport systems inner membrane component  43.08 
 
 
305 aa  137  2e-31  Actinosynnema mirum DSM 43827  Bacteria  normal  n/a   
 
 
-
 
NC_011894  Mnod_5668  binding-protein-dependent transport systems inner membrane component  32.05 
 
 
315 aa  137  3.0000000000000003e-31  Methylobacterium nodulans ORS 2060  Bacteria  normal  n/a   
 
 
-
 
NC_009616  Tmel_1819  binding-protein-dependent transport systems inner membrane component  30.04 
 
 
293 aa  137  3.0000000000000003e-31  Thermosipho melanesiensis BI429  Bacteria  normal  0.215175  n/a   
 
 
-
 
NC_013595  Sros_3340  binding-protein-dependent transport systems inner membrane component  33.45 
 
 
338 aa  136  4e-31  Streptosporangium roseum DSM 43021  Bacteria  normal  0.781064  normal  0.179396 
 
 
-
 
NC_010717  PXO_00881  ABC transporter sugar permease  33.95 
 
 
294 aa  136  4e-31  Xanthomonas oryzae pv. oryzae PXO99A  Bacteria  normal  0.0244413  n/a   
 
 
-
 
NC_013923  Nmag_3872  binding-protein-dependent transport systems inner membrane component  30.63 
 
 
315 aa  136  4e-31  Natrialba magadii ATCC 43099  Archaea  normal  0.0566045  n/a   
 
 
-
 
NC_009620  Smed_3811  binding-protein-dependent transport systems inner membrane component  30.54 
 
 
328 aa  136  4e-31  Sinorhizobium medicae WSM419  Bacteria  normal  normal 
 
 
-
 
NC_009504  BOV_A0280  sugar ABC transporter, permease protein  28.62 
 
 
325 aa  135  9e-31  Brucella ovis ATCC 25840  Bacteria  normal  n/a   
 
 
-
 
NC_004311  BRA0305  sugar ABC transporter, permease protein  28.62 
 
 
325 aa  135  9.999999999999999e-31  Brucella suis 1330  Bacteria  normal  0.0474821  n/a   
 
 
-
 
NC_010483  TRQ2_0971  binding-protein-dependent transport systems inner membrane component  31.12 
 
 
293 aa  135  9.999999999999999e-31  Thermotoga sp. RQ2  Bacteria  normal  0.0994152  n/a   
 
 
-
 
NC_012669  Bcav_1681  binding-protein-dependent transport systems inner membrane component  33.7 
 
 
316 aa  135  9.999999999999999e-31  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.130846  normal 
 
 
-
 
NC_009486  Tpet_0955  binding-protein-dependent transport systems inner membrane component  31.12 
 
 
293 aa  135  9.999999999999999e-31  Thermotoga petrophila RKU-1  Bacteria  normal  n/a   
 
 
-
 
NC_014165  Tbis_1885  binding-protein-dependent transporter inner membrane component  35.51 
 
 
317 aa  134  1.9999999999999998e-30  Thermobispora bispora DSM 43833  Bacteria  normal  normal  0.44963 
 
 
-
 
NC_008346  Swol_0404  ABC sugar transporter, inner membrane subunit  33.21 
 
 
294 aa  134  1.9999999999999998e-30  Syntrophomonas wolfei subsp. wolfei str. Goettingen  Bacteria  normal  n/a   
 
 
-
 
NC_011831  Cagg_2193  binding-protein-dependent transport systems inner membrane component  33.33 
 
 
306 aa  134  1.9999999999999998e-30  Chloroflexus aggregans DSM 9485  Bacteria  normal  0.692762  normal 
 
 
-
 
NC_009636  Smed_0187  binding-protein-dependent transport systems inner membrane component  34.04 
 
 
307 aa  134  1.9999999999999998e-30  Sinorhizobium medicae WSM419  Bacteria  normal  normal 
 
 
-
 
NC_009952  Dshi_1354  binding-protein-dependent transport systems inner membrane component  35.74 
 
 
416 aa  134  1.9999999999999998e-30  Dinoroseobacter shibae DFL 12  Bacteria  normal  normal  0.27612 
 
 
-
 
NC_011368  Rleg2_5492  binding-protein-dependent transport systems inner membrane component  31.21 
 
 
328 aa  134  3e-30  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  0.511246  normal  0.17987 
 
 
-
 
NC_009012  Cthe_1019  binding-protein-dependent transport systems inner membrane component  30.74 
 
 
327 aa  133  3e-30  Clostridium thermocellum ATCC 27405  Bacteria  normal  0.103701  n/a   
 
 
-
 
NC_009485  BBta_1755  ABC transporter permease  35.93 
 
 
312 aa  133  3e-30  Bradyrhizobium sp. BTAi1  Bacteria  normal  0.576454  normal  0.392142 
 
 
-
 
NC_013131  Caci_2109  binding-protein-dependent transport systems inner membrane component  35.94 
 
 
312 aa  133  3.9999999999999996e-30  Catenulispora acidiphila DSM 44928  Bacteria  normal  normal  0.376983 
 
 
-
 
NC_009953  Sare_0748  binding-protein-dependent transport systems inner membrane component  32.94 
 
 
337 aa  133  3.9999999999999996e-30  Salinispora arenicola CNS-205  Bacteria  normal  hitchhiker  0.00168888 
 
 
-
 
NC_010320  Teth514_0396  binding-protein-dependent transport systems inner membrane component  29.01 
 
 
307 aa  133  3.9999999999999996e-30  Thermoanaerobacter sp. X514  Bacteria  normal  0.701562  n/a   
 
 
-
 
NC_011981  Avi_7347  ABC transporter membrane spanning protein (sugar)  34.73 
 
 
320 aa  132  6.999999999999999e-30  Agrobacterium vitis S4  Bacteria  normal  n/a   
 
 
-
 
NC_010623  Bphy_4058  binding-protein-dependent transport systems inner membrane component  30.5 
 
 
309 aa  132  1.0000000000000001e-29  Burkholderia phymatum STM815  Bacteria  normal  normal  0.801646 
 
 
-
 
NC_008530  LGAS_1641  ABC-type sugar transport system, permease component  30.53 
 
 
287 aa  131  1.0000000000000001e-29  Lactobacillus gasseri ATCC 33323  Bacteria  decreased coverage  0.00000000401598  normal 
 
 
-
 
NC_008578  Acel_0553  binding-protein-dependent transport systems inner membrane component  30.2 
 
 
339 aa  131  1.0000000000000001e-29  Acidothermus cellulolyticus 11B  Bacteria  normal  normal 
 
 
-
 
NC_013530  Xcel_1370  binding-protein-dependent transport systems inner membrane component  32.41 
 
 
320 aa  131  1.0000000000000001e-29  Xylanimonas cellulosilytica DSM 15894  Bacteria  normal  0.811069  n/a   
 
 
-
 
NC_009654  Mmwyl1_0024  binding-protein-dependent transport systems inner membrane component  29.28 
 
 
320 aa  131  1.0000000000000001e-29  Marinomonas sp. MWYL1  Bacteria  normal  0.227719  normal  0.433481 
 
 
-
 
NC_007494  RSP_3673  ABC sugar transporter, inner membrane subunit  32.75 
 
 
308 aa  130  2.0000000000000002e-29  Rhodobacter sphaeroides 2.4.1  Bacteria  normal  0.246744  n/a   
 
 
-
 
NC_009050  Rsph17029_3408  binding-protein-dependent transport systems inner membrane component  32.75 
 
 
308 aa  131  2.0000000000000002e-29  Rhodobacter sphaeroides ATCC 17029  Bacteria  normal  0.166359  normal  0.855546 
 
 
-
 
NC_010676  Bphyt_7207  binding-protein-dependent transport systems inner membrane component  30.5 
 
 
296 aa  130  2.0000000000000002e-29  Burkholderia phytofirmans PsJN  Bacteria  normal  normal 
 
 
-
 
NC_007952  Bxe_B0419  ABC sugar transporter, inner membrane subunit  30.14 
 
 
296 aa  130  3e-29  Burkholderia xenovorans LB400  Bacteria  normal  normal 
 
 
-
 
NC_013205  Aaci_2047  binding-protein-dependent transport systems inner membrane component  34.27 
 
 
294 aa  130  3e-29  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  0.550241  n/a   
 
 
-
 
NC_013721  HMPREF0424_1315  ABC transporter, permease protein  31.12 
 
 
301 aa  129  4.0000000000000003e-29  Gardnerella vaginalis 409-05  Bacteria  n/a    normal 
 
 
-
 
NC_014210  Ndas_3354  binding-protein-dependent transport systems inner membrane component  31.45 
 
 
299 aa  129  4.0000000000000003e-29  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  normal 
 
 
-
 
NC_008048  Sala_1022  binding-protein-dependent transport systems inner membrane component  35.77 
 
 
294 aa  130  4.0000000000000003e-29  Sphingopyxis alaskensis RB2256  Bacteria  normal  normal 
 
 
-
 
NC_010320  Teth514_0754  binding-protein-dependent transport systems inner membrane component  31.37 
 
 
324 aa  129  5.0000000000000004e-29  Thermoanaerobacter sp. X514  Bacteria  decreased coverage  0.000000204062  n/a   
 
 
-
 
NC_008699  Noca_0870  binding-protein-dependent transport systems inner membrane component  32.04 
 
 
309 aa  129  6e-29  Nocardioides sp. JS614  Bacteria  normal  0.800905  n/a   
 
 
-
 
NC_013131  Caci_3596  binding-protein-dependent transport systems inner membrane component  30.6 
 
 
325 aa  129  8.000000000000001e-29  Catenulispora acidiphila DSM 44928  Bacteria  normal  0.295531  normal 
 
 
-
 
NC_008699  Noca_1419  binding-protein-dependent transport systems inner membrane component  31.63 
 
 
314 aa  129  8.000000000000001e-29  Nocardioides sp. JS614  Bacteria  normal  0.906597  n/a   
 
 
-
 
NC_012848  Rleg_4864  binding-protein-dependent transport systems inner membrane component  30.28 
 
 
319 aa  128  1.0000000000000001e-28  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  0.243677  normal  0.263269 
 
 
-
 
NC_008686  Pden_1048  binding-protein-dependent transport systems inner membrane component  31.18 
 
 
308 aa  128  1.0000000000000001e-28  Paracoccus denitrificans PD1222  Bacteria  normal  normal 
 
 
-
 
NC_013131  Caci_2623  binding-protein-dependent transport systems inner membrane component  30.11 
 
 
330 aa  128  1.0000000000000001e-28  Catenulispora acidiphila DSM 44928  Bacteria  normal  0.0584633  normal 
 
 
-
 
NC_013501  Rmar_0359  binding-protein-dependent transport systems inner membrane component  32.5 
 
 
300 aa  128  1.0000000000000001e-28  Rhodothermus marinus DSM 4252  Bacteria  normal  n/a   
 
 
-
 
NC_011369  Rleg2_3668  binding-protein-dependent transport systems inner membrane component  29.1 
 
 
299 aa  127  2.0000000000000002e-28  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  normal 
 
 
-
 
NC_012669  Bcav_1699  binding-protein-dependent transport systems inner membrane component  33.21 
 
 
315 aa  127  2.0000000000000002e-28  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.258357  normal 
 
 
-
 
NC_002977  MCA1942  sugar ABC transporter, permease protein  32.98 
 
 
287 aa  127  3e-28  Methylococcus capsulatus str. Bath  Bacteria  normal  n/a   
 
 
-
 
NC_011886  Achl_2661  binding-protein-dependent transport systems inner membrane component  34.16 
 
 
320 aa  127  3e-28  Arthrobacter chlorophenolicus A6  Bacteria  n/a    normal 
 
 
-
 
NC_007413  Ava_0461  binding-protein dependent transport system inner membrane protein  31.01 
 
 
301 aa  126  4.0000000000000003e-28  Anabaena variabilis ATCC 29413  Bacteria  normal  normal  0.0667876 
 
 
-
 
NC_008786  Veis_3450  binding-protein-dependent transport systems inner membrane component  30.82 
 
 
307 aa  126  4.0000000000000003e-28  Verminephrobacter eiseniae EF01-2  Bacteria  normal  normal 
 
 
-
 
NC_013595  Sros_2365  sugar ABC transporter, permease protein  35.63 
 
 
288 aa  126  5e-28  Streptosporangium roseum DSM 43021  Bacteria  normal  0.216835  normal 
 
 
-
 
NC_012848  Rleg_5053  binding-protein-dependent transport systems inner membrane component  32.24 
 
 
318 aa  126  5e-28  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  0.0625824  normal 
 
 
-
 
NC_014151  Cfla_0500  binding-protein-dependent transport systems inner membrane component  33.94 
 
 
326 aa  125  6e-28  Cellulomonas flavigena DSM 20109  Bacteria  hitchhiker  0.00625448  hitchhiker  0.0000153504 
 
 
-
 
NC_008541  Arth_2946  binding-protein-dependent transport systems inner membrane component  33.22 
 
 
316 aa  125  6e-28  Arthrobacter sp. FB24  Bacteria  normal  n/a   
 
 
-
 
NC_013595  Sros_9092  trehalose/maltose transport inner membrane protein  30 
 
 
326 aa  125  6e-28  Streptosporangium roseum DSM 43021  Bacteria  normal  0.309735  normal 
 
 
-
 
NC_013745  Htur_4489  binding-protein-dependent transport systems inner membrane component  28.52 
 
 
308 aa  125  6e-28  Haloterrigena turkmenica DSM 5511  Archaea  normal  0.283214  n/a   
 
 
-
 
NC_013131  Caci_2679  binding-protein-dependent transport systems inner membrane component  32.01 
 
 
330 aa  125  6e-28  Catenulispora acidiphila DSM 44928  Bacteria  normal  normal 
 
 
-
 
NC_012848  Rleg_5336  binding-protein-dependent transport systems inner membrane component  31.37 
 
 
310 aa  125  7e-28  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  normal  0.369054 
 
 
-
 
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