More than 300 homologs were found in PanDaTox collection
for query gene Caci_4985 on replicon NC_013131
Organism: Catenulispora acidiphila DSM 44928



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_013131  Caci_4985  binding-protein-dependent transport systems inner membrane component  100 
 
 
313 aa  624  1e-178  Catenulispora acidiphila DSM 44928  Bacteria  hitchhiker  0.00226923  hitchhiker  0.00373728 
 
 
-
 
NC_012669  Bcav_0191  binding-protein-dependent transport systems inner membrane component  51.83 
 
 
317 aa  256  2e-67  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.37513  normal 
 
 
-
 
NC_014213  Mesil_3393  binding-protein-dependent transport systems inner membrane component  49.13 
 
 
291 aa  245  6e-64  Meiothermus silvanus DSM 9946  Bacteria  normal  0.199241  normal  0.935882 
 
 
-
 
NC_012850  Rleg_3429  binding-protein-dependent transport systems inner membrane component  44.21 
 
 
307 aa  233  3e-60  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  normal 
 
 
-
 
NC_009939  Dgeo_3105  ABC transporter, permease component  45.3 
 
 
294 aa  226  3e-58  Deinococcus geothermalis DSM 11300  Bacteria  n/a    n/a   
 
 
-
 
NC_009523  RoseRS_1357  binding-protein-dependent transport systems inner membrane component  39.53 
 
 
316 aa  211  9e-54  Roseiflexus sp. RS-1  Bacteria  normal  normal 
 
 
-
 
NC_011881  Achl_4622  binding-protein-dependent transport systems inner membrane component  40.45 
 
 
317 aa  211  2e-53  Arthrobacter chlorophenolicus A6  Bacteria  n/a    normal 
 
 
-
 
NC_014213  Mesil_3421  binding-protein-dependent transport systems inner membrane component  40 
 
 
307 aa  206  4e-52  Meiothermus silvanus DSM 9946  Bacteria  normal  0.556907  normal 
 
 
-
 
NC_014213  Mesil_3227  extracellular solute-binding protein family 1  40 
 
 
307 aa  206  4e-52  Meiothermus silvanus DSM 9946  Bacteria  decreased coverage  0.00159401  normal  0.987884 
 
 
-
 
NC_011368  Rleg2_5350  binding-protein-dependent transport systems inner membrane component  37.58 
 
 
308 aa  206  4e-52  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  0.84186  normal  0.48209 
 
 
-
 
NC_003909  BCE_0630  glycerol-3-phosphate ABC transporter, permease protein, putative  38.05 
 
 
310 aa  201  1.9999999999999998e-50  Bacillus cereus ATCC 10987  Bacteria  normal  n/a   
 
 
-
 
NC_011658  BCAH187_A0698  putative glycerol-3-phosphate ABC transporter, permease protein  38.18 
 
 
310 aa  199  3e-50  Bacillus cereus AH187  Bacteria  normal  n/a   
 
 
-
 
NC_010184  BcerKBAB4_0481  binding-protein-dependent transport systems inner membrane component  37.5 
 
 
310 aa  198  9e-50  Bacillus weihenstephanensis KBAB4  Bacteria  normal  n/a   
 
 
-
 
NC_011725  BCB4264_A0604  putative glycerol-3-phosphate ABC transporter, permease protein  37.84 
 
 
310 aa  198  1.0000000000000001e-49  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_011772  BCG9842_B4735  putative glycerol-3-phosphate ABC transporter, permease protein  37.46 
 
 
310 aa  197  2.0000000000000003e-49  Bacillus cereus G9842  Bacteria  normal  normal 
 
 
-
 
NC_006274  BCZK0480  glycerol-3-phosphate ABC transporter, permease  38.41 
 
 
310 aa  196  4.0000000000000005e-49  Bacillus cereus E33L  Bacteria  normal  n/a   
 
 
-
 
NC_011773  BCAH820_0623  putative glycerol-3-phosphate ABC transporter, permease protein  38.41 
 
 
310 aa  196  4.0000000000000005e-49  Bacillus cereus AH820  Bacteria  n/a    normal 
 
 
-
 
NC_009767  Rcas_3564  binding-protein-dependent transport systems inner membrane component  39.13 
 
 
316 aa  195  7e-49  Roseiflexus castenholzii DSM 13941  Bacteria  normal  normal  0.264329 
 
 
-
 
NC_005957  BT9727_0478  glycerol-3-phosphate ABC transporter, permease  38.06 
 
 
310 aa  194  1e-48  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  n/a   
 
 
-
 
NC_009939  Dgeo_2918  ABC-type sugar transport system, permease component  38.68 
 
 
305 aa  194  1e-48  Deinococcus geothermalis DSM 11300  Bacteria  n/a    n/a   
 
 
-
 
NC_005945  BAS0536  glycerol-3-phosphate ABC transporter permease  38.06 
 
 
310 aa  194  2e-48  Bacillus anthracis str. Sterne  Bacteria  normal  n/a   
 
 
-
 
NC_007530  GBAA_0567  glycerol-3-phosphate ABC transporter permease protein  38.06 
 
 
310 aa  194  2e-48  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  n/a   
 
 
-
 
NC_008262  CPR_0477  ABC tranporter, permease protein  36.67 
 
 
315 aa  192  4e-48  Clostridium perfringens SM101  Bacteria  normal  n/a   
 
 
-
 
NC_012669  Bcav_0311  binding-protein-dependent transport systems inner membrane component  36.66 
 
 
321 aa  192  5e-48  Beutenbergia cavernae DSM 12333  Bacteria  normal  normal 
 
 
-
 
NC_013526  Tter_2316  binding-protein-dependent transport systems inner membrane component  37.79 
 
 
313 aa  191  1e-47  Thermobaculum terrenum ATCC BAA-798  Bacteria  normal  n/a   
 
 
-
 
NC_011899  Hore_20620  binding-protein-dependent transport systems inner membrane component  35.31 
 
 
299 aa  191  1e-47  Halothermothrix orenii H 168  Bacteria  normal  n/a   
 
 
-
 
NC_010001  Cphy_1390  binding-protein-dependent transport systems inner membrane component  32.89 
 
 
308 aa  191  1e-47  Clostridium phytofermentans ISDg  Bacteria  normal  n/a   
 
 
-
 
NC_012669  Bcav_3990  binding-protein-dependent transport systems inner membrane component  38.46 
 
 
317 aa  191  2e-47  Beutenbergia cavernae DSM 12333  Bacteria  normal  normal 
 
 
-
 
NC_013235  Namu_3848  binding-protein-dependent transport systems inner membrane component  36.51 
 
 
320 aa  190  2.9999999999999997e-47  Nakamurella multipartita DSM 44233  Bacteria  normal  0.0230008  normal  0.429544 
 
 
-
 
NC_009667  Oant_1668  binding-protein-dependent transport systems inner membrane component  35.76 
 
 
310 aa  189  4e-47  Ochrobactrum anthropi ATCC 49188  Bacteria  normal  n/a   
 
 
-
 
NC_013174  Jden_0512  binding-protein-dependent transport systems inner membrane component  37.5 
 
 
318 aa  189  5e-47  Jonesia denitrificans DSM 20603  Bacteria  hitchhiker  0.000000473727  hitchhiker  0.00124128 
 
 
-
 
NC_012793  GWCH70_1390  binding-protein-dependent transport systems inner membrane component  36.24 
 
 
308 aa  185  8e-46  Geobacillus sp. WCH70  Bacteria  normal  n/a   
 
 
-
 
NC_013721  HMPREF0424_1315  ABC transporter, permease protein  35.89 
 
 
301 aa  184  1.0000000000000001e-45  Gardnerella vaginalis 409-05  Bacteria  n/a    normal 
 
 
-
 
NC_012669  Bcav_0321  binding-protein-dependent transport systems inner membrane component  35.33 
 
 
316 aa  184  1.0000000000000001e-45  Beutenbergia cavernae DSM 12333  Bacteria  normal  normal 
 
 
-
 
NC_011831  Cagg_0728  binding-protein-dependent transport systems inner membrane component  38.67 
 
 
313 aa  184  1.0000000000000001e-45  Chloroflexus aggregans DSM 9485  Bacteria  hitchhiker  0.000239391  normal 
 
 
-
 
NC_013521  Sked_27700  permease component of ABC-type sugar transporter  35.47 
 
 
321 aa  184  1.0000000000000001e-45  Sanguibacter keddieii DSM 10542  Bacteria  normal  normal  0.479477 
 
 
-
 
NC_013525  Tter_0830  binding-protein-dependent transport systems inner membrane component  34.21 
 
 
309 aa  184  2.0000000000000003e-45  Thermobaculum terrenum ATCC BAA-798  Bacteria  n/a    n/a   
 
 
-
 
NC_012669  Bcav_3792  binding-protein-dependent transport systems inner membrane component  35.21 
 
 
285 aa  184  2.0000000000000003e-45  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.168129  normal 
 
 
-
 
NC_011886  Achl_3567  binding-protein-dependent transport systems inner membrane component  37.93 
 
 
309 aa  183  4.0000000000000006e-45  Arthrobacter chlorophenolicus A6  Bacteria  n/a    normal 
 
 
-
 
NC_013172  Bfae_29330  permease component of ABC-type sugar transporter  36.04 
 
 
321 aa  182  5.0000000000000004e-45  Brachybacterium faecium DSM 4810  Bacteria  normal  n/a   
 
 
-
 
NC_013526  Tter_2217  binding-protein-dependent transport systems inner membrane component  35.55 
 
 
305 aa  182  9.000000000000001e-45  Thermobaculum terrenum ATCC BAA-798  Bacteria  normal  n/a   
 
 
-
 
NC_013526  Tter_2523  binding-protein-dependent transport systems inner membrane component  34.77 
 
 
309 aa  181  1e-44  Thermobaculum terrenum ATCC BAA-798  Bacteria  hitchhiker  0.00000000325465  n/a   
 
 
-
 
NC_004311  BRA1182  sugar ABC transporter, permease protein, putative  36.54 
 
 
319 aa  180  2e-44  Brucella suis 1330  Bacteria  normal  0.547049  n/a   
 
 
-
 
NC_009504  BOV_A1085  putative sugar ABC transporter, permease protein  36.54 
 
 
319 aa  180  2e-44  Brucella ovis ATCC 25840  Bacteria  normal  0.589946  n/a   
 
 
-
 
NC_009767  Rcas_2545  binding-protein-dependent transport systems inner membrane component  36.21 
 
 
316 aa  179  4.999999999999999e-44  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.637107  normal  0.115222 
 
 
-
 
NC_012669  Bcav_1469  binding-protein-dependent transport systems inner membrane component  36.4 
 
 
283 aa  179  5.999999999999999e-44  Beutenbergia cavernae DSM 12333  Bacteria  normal  normal 
 
 
-
 
NC_007413  Ava_0563  binding-protein dependent transport system inner membrane protein  39.86 
 
 
294 aa  179  5.999999999999999e-44  Anabaena variabilis ATCC 29413  Bacteria  normal  0.22835  normal  0.0558608 
 
 
-
 
NC_009523  RoseRS_2819  binding-protein-dependent transport systems inner membrane component  36.39 
 
 
315 aa  178  9e-44  Roseiflexus sp. RS-1  Bacteria  normal  0.0308401  normal 
 
 
-
 
NC_008699  Noca_4634  binding-protein-dependent transport systems inner membrane component  36.99 
 
 
292 aa  177  1e-43  Nocardioides sp. JS614  Bacteria  normal  0.219562  n/a   
 
 
-
 
NC_013526  Tter_2453  binding-protein-dependent transport systems inner membrane component  34.88 
 
 
314 aa  177  3e-43  Thermobaculum terrenum ATCC BAA-798  Bacteria  hitchhiker  0.000000200699  n/a   
 
 
-
 
NC_011886  Achl_0498  binding-protein-dependent transport systems inner membrane component  35.12 
 
 
317 aa  177  3e-43  Arthrobacter chlorophenolicus A6  Bacteria  n/a    hitchhiker  0.000449996 
 
 
-
 
NC_013205  Aaci_0077  binding-protein-dependent transport systems inner membrane component  34.67 
 
 
311 aa  177  3e-43  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  n/a   
 
 
-
 
NC_013411  GYMC61_0532  binding-protein-dependent transport systems inner membrane component  36.21 
 
 
311 aa  176  4e-43  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_011981  Avi_7347  ABC transporter membrane spanning protein (sugar)  35.26 
 
 
320 aa  176  5e-43  Agrobacterium vitis S4  Bacteria  normal  n/a   
 
 
-
 
NC_003909  BCE_1900  sugar ABC transporter, permease protein, putative  39.16 
 
 
314 aa  176  6e-43  Bacillus cereus ATCC 10987  Bacteria  normal  n/a   
 
 
-
 
NC_006274  BCZK1635  sugar ABC transporter, permease  39.16 
 
 
314 aa  176  6e-43  Bacillus cereus E33L  Bacteria  normal  n/a   
 
 
-
 
NC_009972  Haur_3640  binding-protein-dependent transport systems inner membrane component  36.95 
 
 
298 aa  174  9.999999999999999e-43  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  n/a   
 
 
-
 
NC_013526  Tter_2511  binding-protein-dependent transport systems inner membrane component  39.18 
 
 
317 aa  174  1.9999999999999998e-42  Thermobaculum terrenum ATCC BAA-798  Bacteria  normal  0.10809  n/a   
 
 
-
 
NC_011884  Cyan7425_0944  binding-protein-dependent transport systems inner membrane component  39.45 
 
 
290 aa  173  2.9999999999999996e-42  Cyanothece sp. PCC 7425  Bacteria  normal  0.120711  normal  0.307929 
 
 
-
 
NC_013595  Sros_4987  binding-protein-dependent transport systems inner membrane component  38.23 
 
 
292 aa  173  2.9999999999999996e-42  Streptosporangium roseum DSM 43021  Bacteria  normal  0.753078  normal 
 
 
-
 
NC_013411  GYMC61_2730  binding-protein-dependent transport systems inner membrane component  35.49 
 
 
300 aa  173  2.9999999999999996e-42  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_013235  Namu_0513  binding-protein-dependent transport systems inner membrane component  36.94 
 
 
314 aa  172  5.999999999999999e-42  Nakamurella multipartita DSM 44233  Bacteria  normal  normal 
 
 
-
 
NC_013739  Cwoe_3982  binding-protein-dependent transport systems inner membrane component  37.63 
 
 
316 aa  171  1e-41  Conexibacter woesei DSM 14684  Bacteria  normal  normal 
 
 
-
 
NC_013521  Sked_21160  carbohydrate ABC transporter membrane protein  35.5 
 
 
314 aa  170  2e-41  Sanguibacter keddieii DSM 10542  Bacteria  normal  0.103465  normal  0.100515 
 
 
-
 
NC_009664  Krad_0295  binding-protein-dependent transport systems inner membrane component  39.58 
 
 
306 aa  170  2e-41  Kineococcus radiotolerans SRS30216  Bacteria  normal  normal  0.0472746 
 
 
-
 
NC_010001  Cphy_0620  binding-protein-dependent transport systems inner membrane component  34.04 
 
 
305 aa  170  3e-41  Clostridium phytofermentans ISDg  Bacteria  hitchhiker  0.000205165  n/a   
 
 
-
 
NC_009616  Tmel_1015  binding-protein-dependent transport systems inner membrane component  34.02 
 
 
292 aa  170  4e-41  Thermosipho melanesiensis BI429  Bacteria  normal  n/a   
 
 
-
 
NC_012669  Bcav_2602  binding-protein-dependent transport systems inner membrane component  37.24 
 
 
306 aa  169  6e-41  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.0924232  normal 
 
 
-
 
NC_010320  Teth514_2200  binding-protein-dependent transport systems inner membrane component  34.6 
 
 
299 aa  169  7e-41  Thermoanaerobacter sp. X514  Bacteria  normal  0.426381  n/a   
 
 
-
 
NC_009486  Tpet_0117  binding-protein-dependent transport systems inner membrane component  32.65 
 
 
300 aa  169  8e-41  Thermotoga petrophila RKU-1  Bacteria  normal  n/a   
 
 
-
 
NC_010483  TRQ2_0115  binding-protein-dependent transport systems inner membrane component  32.65 
 
 
300 aa  169  8e-41  Thermotoga sp. RQ2  Bacteria  normal  n/a   
 
 
-
 
NC_013526  Tter_2208  binding-protein-dependent transport systems inner membrane component  34.9 
 
 
306 aa  168  1e-40  Thermobaculum terrenum ATCC BAA-798  Bacteria  normal  0.739705  n/a   
 
 
-
 
NC_008541  Arth_3147  binding-protein-dependent transport systems inner membrane component  37.87 
 
 
319 aa  168  1e-40  Arthrobacter sp. FB24  Bacteria  hitchhiker  0.00382098  n/a   
 
 
-
 
NC_010001  Cphy_3401  binding-protein-dependent transport systems inner membrane component  31.71 
 
 
305 aa  168  1e-40  Clostridium phytofermentans ISDg  Bacteria  normal  0.028536  n/a   
 
 
-
 
NC_013131  Caci_6731  binding-protein-dependent transport systems inner membrane component  37.58 
 
 
337 aa  167  2e-40  Catenulispora acidiphila DSM 44928  Bacteria  normal  0.0579092  normal 
 
 
-
 
NC_010001  Cphy_3032  binding-protein-dependent transport systems inner membrane component  35.5 
 
 
307 aa  167  2e-40  Clostridium phytofermentans ISDg  Bacteria  normal  n/a   
 
 
-
 
NC_012669  Bcav_0016  binding-protein-dependent transport systems inner membrane component  34.55 
 
 
311 aa  167  2.9999999999999998e-40  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.17058  normal 
 
 
-
 
NC_007604  Synpcc7942_0526  ABC-type sugar transport systems permease components-like  34.64 
 
 
293 aa  167  2.9999999999999998e-40  Synechococcus elongatus PCC 7942  Bacteria  normal  normal 
 
 
-
 
NC_013172  Bfae_29410  carbohydrate ABC transporter membrane protein  34.3 
 
 
322 aa  166  4e-40  Brachybacterium faecium DSM 4810  Bacteria  normal  0.899558  n/a   
 
 
-
 
NC_008578  Acel_2048  binding-protein-dependent transport systems inner membrane component  32.76 
 
 
332 aa  166  6.9999999999999995e-40  Acidothermus cellulolyticus 11B  Bacteria  normal  normal 
 
 
-
 
NC_012669  Bcav_0828  binding-protein-dependent transport systems inner membrane component  35.71 
 
 
316 aa  165  8e-40  Beutenbergia cavernae DSM 12333  Bacteria  normal  normal  0.194369 
 
 
-
 
NC_010001  Cphy_0527  binding-protein-dependent transport systems inner membrane component  37.07 
 
 
296 aa  165  9e-40  Clostridium phytofermentans ISDg  Bacteria  hitchhiker  0.0000000283647  n/a   
 
 
-
 
NC_013205  Aaci_2047  binding-protein-dependent transport systems inner membrane component  36.52 
 
 
294 aa  165  1.0000000000000001e-39  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  0.550241  n/a   
 
 
-
 
NC_012848  Rleg_5053  binding-protein-dependent transport systems inner membrane component  34.54 
 
 
318 aa  165  1.0000000000000001e-39  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  0.0625824  normal 
 
 
-
 
NC_012034  Athe_2375  binding-protein-dependent transport systems inner membrane component  34.71 
 
 
298 aa  164  1.0000000000000001e-39  Anaerocellum thermophilum DSM 6725  Bacteria  normal  n/a   
 
 
-
 
NC_008752  Aave_3651  binding-protein-dependent transport systems inner membrane component  33.44 
 
 
301 aa  165  1.0000000000000001e-39  Acidovorax citrulli AAC00-1  Bacteria  normal  0.0332234  normal 
 
 
-
 
NC_011368  Rleg2_5336  binding-protein-dependent transport systems inner membrane component  33.86 
 
 
318 aa  165  1.0000000000000001e-39  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  0.949955  normal 
 
 
-
 
NC_013526  Tter_2302  binding-protein-dependent transport systems inner membrane component  33.33 
 
 
320 aa  165  1.0000000000000001e-39  Thermobaculum terrenum ATCC BAA-798  Bacteria  normal  0.253823  n/a   
 
 
-
 
NC_014151  Cfla_1127  binding-protein-dependent transport systems inner membrane component  33.89 
 
 
328 aa  165  1.0000000000000001e-39  Cellulomonas flavigena DSM 20109  Bacteria  normal  0.190953  hitchhiker  0.00155627 
 
 
-
 
NC_012669  Bcav_3898  binding-protein-dependent transport systems inner membrane component  32.25 
 
 
324 aa  164  2.0000000000000002e-39  Beutenbergia cavernae DSM 12333  Bacteria  normal  normal 
 
 
-
 
NC_009616  Tmel_0691  binding-protein-dependent transport systems inner membrane component  34.72 
 
 
295 aa  164  2.0000000000000002e-39  Thermosipho melanesiensis BI429  Bacteria  normal  n/a   
 
 
-
 
NC_013411  GYMC61_2847  binding-protein-dependent transport systems inner membrane component  33.66 
 
 
318 aa  164  2.0000000000000002e-39  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_007958  RPD_3149  binding-protein-dependent transport systems inner membrane component  36.19 
 
 
315 aa  164  3e-39  Rhodopseudomonas palustris BisB5  Bacteria  normal  0.0566553  normal  0.330059 
 
 
-
 
NC_013131  Caci_2030  binding-protein-dependent transport systems inner membrane component  37.98 
 
 
297 aa  163  3e-39  Catenulispora acidiphila DSM 44928  Bacteria  normal  normal  0.185813 
 
 
-
 
NC_012669  Bcav_2833  binding-protein-dependent transport systems inner membrane component  34.12 
 
 
319 aa  163  4.0000000000000004e-39  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.0200859  normal 
 
 
-
 
NC_010184  BcerKBAB4_2801  binding-protein-dependent transport systems inner membrane component  36.44 
 
 
288 aa  162  5.0000000000000005e-39  Bacillus weihenstephanensis KBAB4  Bacteria  normal  0.254018  n/a   
 
 
-
 
NC_013131  Caci_4319  binding-protein-dependent transport systems inner membrane component  34.69 
 
 
312 aa  162  5.0000000000000005e-39  Catenulispora acidiphila DSM 44928  Bacteria  normal  0.778687  hitchhiker  0.00185272 
 
 
-
 
NC_012669  Bcav_2718  binding-protein-dependent transport systems inner membrane component  36.33 
 
 
330 aa  162  6e-39  Beutenbergia cavernae DSM 12333  Bacteria  normal  normal  0.21265 
 
 
-
 
NC_012669  Bcav_3676  binding-protein-dependent transport systems inner membrane component  34.15 
 
 
309 aa  162  6e-39  Beutenbergia cavernae DSM 12333  Bacteria  normal  normal 
 
 
-
 
NC_013595  Sros_2365  sugar ABC transporter, permease protein  32.04 
 
 
288 aa  162  6e-39  Streptosporangium roseum DSM 43021  Bacteria  normal  0.216835  normal 
 
 
-
 
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