More than 300 homologs were found in PanDaTox collection
for query gene Noca_0454 on replicon NC_008699
Organism: Nocardioides sp. JS614



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_008699  Noca_0454  binding-protein-dependent transport systems inner membrane component  100 
 
 
257 aa  493  9.999999999999999e-139  Nocardioides sp. JS614  Bacteria  normal  n/a   
 
 
-
 
NC_012669  Bcav_2670  binding-protein-dependent transport systems inner membrane component  42.54 
 
 
230 aa  147  2.0000000000000003e-34  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.538253  normal  0.0824918 
 
 
-
 
NC_013595  Sros_8179  proline/glycine betaine ABC transporter  43.26 
 
 
223 aa  139  3.9999999999999997e-32  Streptosporangium roseum DSM 43021  Bacteria  normal  normal 
 
 
-
 
NC_013510  Tcur_3634  binding-protein-dependent transport systems inner membrane component  37.02 
 
 
229 aa  137  2e-31  Thermomonospora curvata DSM 43183  Bacteria  normal  0.737383  n/a   
 
 
-
 
NC_013169  Ksed_26240  ABC-type proline/glycine betaine transport system, permease component  41.78 
 
 
230 aa  135  8e-31  Kytococcus sedentarius DSM 20547  Bacteria  normal  0.408698  normal  0.833764 
 
 
-
 
NC_013757  Gobs_0624  binding-protein-dependent transport systems inner membrane component  44.67 
 
 
243 aa  129  3e-29  Geodermatophilus obscurus DSM 43160  Bacteria  normal  n/a   
 
 
-
 
NC_013947  Snas_1035  binding-protein-dependent transport systems inner membrane component  40 
 
 
236 aa  128  8.000000000000001e-29  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  normal  0.163683 
 
 
-
 
NC_011989  Avi_0503  ABC transporter  41.94 
 
 
225 aa  127  1.0000000000000001e-28  Agrobacterium vitis S4  Bacteria  normal  n/a   
 
 
-
 
NC_013521  Sked_37580  ABC-type proline/glycine betaine transport system, permease component  41.23 
 
 
228 aa  127  3e-28  Sanguibacter keddieii DSM 10542  Bacteria  normal  normal 
 
 
-
 
NC_014151  Cfla_1339  binding-protein-dependent transport systems inner membrane component  42.22 
 
 
255 aa  125  7e-28  Cellulomonas flavigena DSM 20109  Bacteria  normal  0.889629  hitchhiker  0.000819014 
 
 
-
 
NC_013174  Jden_2260  binding-protein-dependent transport systems inner membrane component  40.85 
 
 
227 aa  122  4e-27  Jonesia denitrificans DSM 20603  Bacteria  normal  normal  0.360102 
 
 
-
 
NC_009664  Krad_1292  binding-protein-dependent transport systems inner membrane component  45.33 
 
 
251 aa  122  4e-27  Kineococcus radiotolerans SRS30216  Bacteria  normal  normal 
 
 
-
 
NC_013131  Caci_3085  binding-protein-dependent transport systems inner membrane component  37.67 
 
 
225 aa  121  9.999999999999999e-27  Catenulispora acidiphila DSM 44928  Bacteria  normal  0.416296  normal  0.12861 
 
 
-
 
NC_014210  Ndas_0399  binding-protein-dependent transport systems inner membrane component  42.27 
 
 
225 aa  121  9.999999999999999e-27  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  normal 
 
 
-
 
NC_013421  Pecwa_4555  binding-protein-dependent transport systems inner membrane component  40 
 
 
226 aa  117  1.9999999999999998e-25  Pectobacterium wasabiae WPP163  Bacteria  normal  n/a   
 
 
-
 
NC_009972  Haur_0349  binding-protein-dependent transport systems inner membrane component  40.53 
 
 
217 aa  116  3.9999999999999997e-25  Herpetosiphon aurantiacus ATCC 23779  Bacteria  hitchhiker  0.0000441273  n/a   
 
 
-
 
NC_013235  Namu_1404  binding-protein-dependent transport systems inner membrane component  42.86 
 
 
258 aa  115  5e-25  Nakamurella multipartita DSM 44233  Bacteria  normal  normal  0.848892 
 
 
-
 
NC_013093  Amir_6269  binding-protein-dependent transport systems inner membrane component  39.7 
 
 
243 aa  113  2.0000000000000002e-24  Actinosynnema mirum DSM 43827  Bacteria  normal  n/a   
 
 
-
 
NC_013739  Cwoe_3263  binding-protein-dependent transport systems inner membrane component  38.22 
 
 
229 aa  113  3e-24  Conexibacter woesei DSM 14684  Bacteria  normal  normal  0.0142604 
 
 
-
 
NC_013204  Elen_0084  Substrate-binding region of ABC-type glycine betaine transport system  35.07 
 
 
528 aa  113  3e-24  Eggerthella lenta DSM 2243  Bacteria  normal  0.689632  normal 
 
 
-
 
NC_009953  Sare_4724  binding-protein-dependent transport systems inner membrane component  41.55 
 
 
244 aa  112  6e-24  Salinispora arenicola CNS-205  Bacteria  normal  decreased coverage  0.0000283909 
 
 
-
 
NC_009380  Strop_4289  binding-protein-dependent transport systems inner membrane component  41.1 
 
 
244 aa  112  8.000000000000001e-24  Salinispora tropica CNB-440  Bacteria  normal  0.729168  normal  0.839045 
 
 
-
 
NC_008146  Mmcs_4964  binding-protein-dependent transport systems inner membrane component  35.32 
 
 
264 aa  107  3e-22  Mycobacterium sp. MCS  Bacteria  normal  0.517846  n/a   
 
 
-
 
NC_009077  Mjls_5345  binding-protein-dependent transport systems inner membrane component  35.32 
 
 
264 aa  107  3e-22  Mycobacterium sp. JLS  Bacteria  normal  0.214986  normal 
 
 
-
 
NC_008705  Mkms_5052  binding-protein-dependent transport systems inner membrane component  35.32 
 
 
264 aa  107  3e-22  Mycobacterium sp. KMS  Bacteria  normal  normal 
 
 
-
 
NC_011886  Achl_2555  binding-protein-dependent transport systems inner membrane component  31.67 
 
 
248 aa  105  5e-22  Arthrobacter chlorophenolicus A6  Bacteria  n/a    hitchhiker  0.0000000304534 
 
 
-
 
NC_002976  SERP0386  ABC transporter, permease protein  31.68 
 
 
504 aa  104  1e-21  Staphylococcus epidermidis RP62A  Bacteria  normal  n/a   
 
 
-
 
NC_004116  SAG0243  amino acid ABC transporter, permease protein  30.96 
 
 
211 aa  103  2e-21  Streptococcus agalactiae 2603V/R  Bacteria  normal  n/a   
 
 
-
 
NC_007952  Bxe_B2995  glycine betaine/choline/proline ABC transporter inner membrane protein  36.55 
 
 
238 aa  103  4e-21  Burkholderia xenovorans LB400  Bacteria  normal  normal 
 
 
-
 
NC_008148  Rxyl_0983  binding-protein-dependent transport systems inner membrane component  41.29 
 
 
217 aa  102  4e-21  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  0.762927  n/a   
 
 
-
 
NC_008541  Arth_2840  binding-protein-dependent transport systems inner membrane component  31.25 
 
 
248 aa  102  5e-21  Arthrobacter sp. FB24  Bacteria  decreased coverage  0.00306406  n/a   
 
 
-
 
NC_012850  Rleg_0148  binding-protein-dependent transport systems inner membrane component  44.59 
 
 
249 aa  101  1e-20  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  normal 
 
 
-
 
NC_013730  Slin_0317  binding-protein-dependent transport systems inner membrane component  36.7 
 
 
519 aa  100  2e-20  Spirosoma linguale DSM 74  Bacteria  normal  normal  0.417886 
 
 
-
 
NC_009565  TBFG_13788  osmoprotectant (glycine betaine/carnitine/choline/L-proline) transport system permease protein proZ  38.07 
 
 
239 aa  100  2e-20  Mycobacterium tuberculosis F11  Bacteria  normal  normal  0.991425 
 
 
-
 
NC_009523  RoseRS_1817  binding-protein-dependent transport systems inner membrane component  43.56 
 
 
217 aa  100  3e-20  Roseiflexus sp. RS-1  Bacteria  normal  normal  0.0299279 
 
 
-
 
NC_009632  SaurJH1_0763  substrate-binding region of ABC-type glycine betaine transport system  32.31 
 
 
504 aa  99.8  4e-20  Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  0.458546  n/a   
 
 
-
 
NC_009487  SaurJH9_0746  substrate-binding region of ABC-type glycine betaine transport system  32.31 
 
 
504 aa  99.8  4e-20  Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  n/a   
 
 
-
 
NC_011369  Rleg2_0142  binding-protein-dependent transport systems inner membrane component  43.92 
 
 
249 aa  99.4  5e-20  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  normal  0.0957565 
 
 
-
 
NC_007509  Bcep18194_C7550  ABC glycinebetaine/carnitine/choline transporter, inner membrane subunit  36.92 
 
 
238 aa  99  6e-20  Burkholderia sp. 383  Bacteria  normal  0.93042  normal  0.508329 
 
 
-
 
NC_007963  Csal_2944  binding-protein-dependent transport systems inner membrane component  36.89 
 
 
400 aa  97.4  2e-19  Chromohalobacter salexigens DSM 3043  Bacteria  normal  0.543286  n/a   
 
 
-
 
NC_008148  Rxyl_0579  binding-protein-dependent transport systems inner membrane component  37.75 
 
 
217 aa  97.4  2e-19  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  0.584474  n/a   
 
 
-
 
NC_013517  Sterm_1515  Substrate-binding region of ABC-type glycine betaine transport system  31.07 
 
 
526 aa  97.1  3e-19  Sebaldella termitidis ATCC 33386  Bacteria  normal  0.0692577  n/a   
 
 
-
 
NC_010512  Bcenmc03_6581  binding-protein-dependent transport systems inner membrane component  35.9 
 
 
238 aa  96.7  3e-19  Burkholderia cenocepacia MC0-3  Bacteria  normal  0.191415  normal  0.0371863 
 
 
-
 
NC_010320  Teth514_1202  binding-protein-dependent transport systems inner membrane component  31.31 
 
 
212 aa  96.7  3e-19  Thermoanaerobacter sp. X514  Bacteria  normal  n/a   
 
 
-
 
NC_008062  Bcen_5735  binding-protein-dependent transport systems inner membrane component  35.9 
 
 
238 aa  97.1  3e-19  Burkholderia cenocepacia AU 1054  Bacteria  normal  0.224143  n/a   
 
 
-
 
NC_008544  Bcen2424_6099  binding-protein-dependent transport systems inner membrane component  35.9 
 
 
238 aa  97.1  3e-19  Burkholderia cenocepacia HI2424  Bacteria  normal  0.840273  normal 
 
 
-
 
NC_013530  Xcel_1079  binding-protein-dependent transport systems inner membrane component  41.78 
 
 
225 aa  96.3  4e-19  Xylanimonas cellulosilytica DSM 15894  Bacteria  normal  0.663107  n/a   
 
 
-
 
NC_009767  Rcas_2528  binding-protein-dependent transport systems inner membrane component  38.05 
 
 
217 aa  95.9  5e-19  Roseiflexus castenholzii DSM 13941  Bacteria  normal  hitchhiker  0.00802547 
 
 
-
 
NC_004310  BR0222  ABC transporter, permease protein  40.79 
 
 
248 aa  95.9  6e-19  Brucella suis 1330  Bacteria  normal  n/a   
 
 
-
 
NC_008254  Meso_2980  binding-protein-dependent transport systems inner membrane component  32.62 
 
 
211 aa  95.9  6e-19  Chelativorans sp. BNC1  Bacteria  normal  n/a   
 
 
-
 
NC_009505  BOV_0213  ABC transporter, permease protein  40.79 
 
 
248 aa  95.9  6e-19  Brucella ovis ATCC 25840  Bacteria  normal  n/a   
 
 
-
 
NC_004116  SAG0241  amino acid ABC transporter, permease protein  33.04 
 
 
213 aa  95.5  7e-19  Streptococcus agalactiae 2603V/R  Bacteria  normal  n/a   
 
 
-
 
NC_007948  Bpro_1155  binding-protein-dependent transport systems inner membrane component  36.16 
 
 
213 aa  95.1  1e-18  Polaromonas sp. JS666  Bacteria  normal  normal 
 
 
-
 
NC_008726  Mvan_5598  binding-protein-dependent transport systems inner membrane component  33.66 
 
 
264 aa  95.1  1e-18  Mycobacterium vanbaalenii PYR-1  Bacteria  normal  normal 
 
 
-
 
NC_002976  SERP2355  amino acid ABC transporter, permease protein  32.68 
 
 
215 aa  94  2e-18  Staphylococcus epidermidis RP62A  Bacteria  normal  n/a   
 
 
-
 
NC_010505  Mrad2831_4887  binding-protein-dependent transport systems inner membrane component  41.18 
 
 
247 aa  94  2e-18  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  0.659147  hitchhiker  0.00742235 
 
 
-
 
NC_009338  Mflv_1210  binding-protein-dependent transport systems inner membrane component  33.66 
 
 
257 aa  94.4  2e-18  Mycobacterium gilvum PYR-GCK  Bacteria  normal  normal 
 
 
-
 
NC_009620  Smed_4640  binding-protein-dependent transport systems inner membrane component  40.52 
 
 
246 aa  94  2e-18  Sinorhizobium medicae WSM419  Bacteria  normal  0.0951209  normal  0.118631 
 
 
-
 
NC_012793  GWCH70_0296  binding-protein-dependent transport systems inner membrane component  35.29 
 
 
211 aa  93.6  3e-18  Geobacillus sp. WCH70  Bacteria  normal  0.4946  n/a   
 
 
-
 
NC_013037  Dfer_1250  binding-protein-dependent transport systems inner membrane component  37.65 
 
 
525 aa  93.6  3e-18  Dyadobacter fermentans DSM 18053  Bacteria  normal  0.615651  normal  0.522042 
 
 
-
 
NC_008527  LACR_0914  choline ABC transporter permease and substrate binding protein  30.1 
 
 
500 aa  93.6  3e-18  Lactococcus lactis subsp. cremoris SK11  Bacteria  normal  0.222381  n/a   
 
 
-
 
NC_013223  Dret_0770  binding-protein-dependent transport systems inner membrane component  36.16 
 
 
222 aa  93.2  4e-18  Desulfohalobium retbaense DSM 5692  Bacteria  normal  normal 
 
 
-
 
NC_009380  Strop_1636  binding-protein-dependent transport systems inner membrane component  35.12 
 
 
242 aa  92.4  6e-18  Salinispora tropica CNB-440  Bacteria  normal  normal  0.537762 
 
 
-
 
NC_009767  Rcas_2531  binding-protein-dependent transport systems inner membrane component  38.25 
 
 
213 aa  92  9e-18  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.41546  hitchhiker  0.00151664 
 
 
-
 
NC_011898  Ccel_3333  Substrate-binding region of ABC-type glycine betaine transport system  24.55 
 
 
524 aa  91.3  1e-17  Clostridium cellulolyticum H10  Bacteria  hitchhiker  0.0000937167  n/a   
 
 
-
 
NC_008148  Rxyl_0984  binding-protein-dependent transport systems inner membrane component  39.16 
 
 
236 aa  91.3  1e-17  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  0.660466  n/a   
 
 
-
 
NC_008347  Mmar10_1070  substrate-binding region of ABC-type glycine betaine transport system  32.41 
 
 
525 aa  91.7  1e-17  Maricaulis maris MCS10  Bacteria  normal  0.019749  normal 
 
 
-
 
NC_008463  PA14_13610  ABC transporter permease  36.99 
 
 
240 aa  91.7  1e-17  Pseudomonas aeruginosa UCBPP-PA14  Bacteria  normal  normal 
 
 
-
 
NC_008531  LEUM_1017  ABC-type proline/glycine betaine transport systems, permease and substrate binding protein  34.48 
 
 
508 aa  91.7  1e-17  Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293  Bacteria  unclonable  0.00355742  n/a   
 
 
-
 
NC_009523  RoseRS_1814  binding-protein-dependent transport systems inner membrane component  35.1 
 
 
213 aa  91.3  1e-17  Roseiflexus sp. RS-1  Bacteria  normal  0.518824  normal  0.0107204 
 
 
-
 
NC_009667  Oant_0296  binding-protein-dependent transport systems inner membrane component  36.27 
 
 
248 aa  90.5  2e-17  Ochrobactrum anthropi ATCC 49188  Bacteria  normal  n/a   
 
 
-
 
NC_009436  Ent638_1924  binding-protein-dependent transport systems inner membrane component  34 
 
 
245 aa  90.5  2e-17  Enterobacter sp. 638  Bacteria  normal  normal 
 
 
-
 
NC_010001  Cphy_0119  substrate-binding region of ABC-type glycine betaine transport system  30.22 
 
 
523 aa  91.3  2e-17  Clostridium phytofermentans ISDg  Bacteria  hitchhiker  0.000124345  n/a   
 
 
-
 
NC_010159  YpAngola_A1330  quaternary amine ABC transporter permease  34.47 
 
 
384 aa  90.5  2e-17  Yersinia pestis Angola  Bacteria  normal  normal 
 
 
-
 
NC_008148  Rxyl_0578  binding-protein-dependent transport systems inner membrane component  39.16 
 
 
235 aa  90.9  2e-17  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  0.0139749  n/a   
 
 
-
 
NC_013440  Hoch_5205  Substrate-binding region of ABC-type glycine betaine transport system  38.38 
 
 
537 aa  91.3  2e-17  Haliangium ochraceum DSM 14365  Bacteria  normal  0.057164  normal 
 
 
-
 
NC_010465  YPK_2864  binding-protein-dependent transport systems inner membrane component  34.47 
 
 
384 aa  90.5  2e-17  Yersinia pseudotuberculosis YPIII  Bacteria  normal  n/a   
 
 
-
 
NC_009513  Lreu_0185  binding-protein-dependent transport systems inner membrane component  33.69 
 
 
221 aa  90.9  2e-17  Lactobacillus reuteri DSM 20016  Bacteria  normal  n/a   
 
 
-
 
NC_009708  YpsIP31758_2785  quaternary amine ABC transporter permease  34.47 
 
 
384 aa  90.5  2e-17  Yersinia pseudotuberculosis IP 31758  Bacteria  normal  n/a   
 
 
-
 
NC_010658  SbBS512_E0843  ABC transporter, quaternary amine uptake (QAT) family, permease protein  33.67 
 
 
385 aa  89.7  4e-17  Shigella boydii CDC 3083-94  Bacteria  normal  n/a   
 
 
-
 
NC_002976  SERP2030  amino acid ABC transporter, permease protein  29.38 
 
 
211 aa  89.4  5e-17  Staphylococcus epidermidis RP62A  Bacteria  normal  0.207242  n/a   
 
 
-
 
NC_009436  Ent638_2729  binding-protein-dependent transport systems inner membrane component  32.66 
 
 
385 aa  89.4  5e-17  Enterobacter sp. 638  Bacteria  normal  normal 
 
 
-
 
NC_007963  Csal_2355  binding-protein-dependent transport systems inner membrane component  31.62 
 
 
243 aa  89.4  5e-17  Chromohalobacter salexigens DSM 3043  Bacteria  normal  n/a   
 
 
-
 
CP001637  EcDH1_1527  binding-protein-dependent transport systems inner membrane component  34.18 
 
 
385 aa  89  6e-17  Escherichia coli DH1  Bacteria  normal  0.782089  n/a   
 
 
-
 
NC_003909  BCE_2314  glycine betaine/L-proline ABC transporter, permease protein, putative  35.12 
 
 
503 aa  89  7e-17  Bacillus cereus ATCC 10987  Bacteria  normal  0.0653078  n/a   
 
 
-
 
NC_009801  EcE24377A_2419  quaternary amine ABC transporter permease  33.67 
 
 
385 aa  89  7e-17  Escherichia coli E24377A  Bacteria  normal  n/a   
 
 
-
 
NC_009621  Smed_5106  binding-protein-dependent transport systems inner membrane component  29.59 
 
 
220 aa  89  7e-17  Sinorhizobium medicae WSM419  Bacteria  normal  0.485727  normal  0.10095 
 
 
-
 
NC_009656  PSPA7_1218  ABC transporter permease  36.84 
 
 
240 aa  89  7e-17  Pseudomonas aeruginosa PA7  Bacteria  normal  n/a   
 
 
-
 
NC_002976  SERP2357  amino acid ABC transporter, permease protein  28.87 
 
 
211 aa  88.6  8e-17  Staphylococcus epidermidis RP62A  Bacteria  normal  n/a   
 
 
-
 
NC_009727  CBUD_1923  glycine betaine transport system permease protein  33.5 
 
 
526 aa  88.6  8e-17  Coxiella burnetii Dugway 5J108-111  Bacteria  normal  n/a   
 
 
-
 
NC_011083  SeHA_C1664  binding-protein-dependent transport systems inner membrane component  33.67 
 
 
236 aa  88.6  8e-17  Salmonella enterica subsp. enterica serovar Heidelberg str. SL476  Bacteria  normal  normal 
 
 
-
 
NC_011205  SeD_A1845  binding-protein-dependent transport systems inner membrane component  33.67 
 
 
236 aa  88.6  8e-17  Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853  Bacteria  normal  0.309897  normal 
 
 
-
 
NC_011080  SNSL254_A1605  binding-protein-dependent transport systems inner membrane component  33.67 
 
 
236 aa  88.6  8e-17  Salmonella enterica subsp. enterica serovar Newport str. SL254  Bacteria  normal  normal 
 
 
-
 
NC_011094  SeSA_A1596  binding-protein-dependent transport systems inner membrane component  33.67 
 
 
236 aa  88.6  8e-17  Salmonella enterica subsp. enterica serovar Schwarzengrund str. CVM19633  Bacteria  normal  0.82645  normal  0.733145 
 
 
-
 
NC_011149  SeAg_B1678  binding-protein-dependent transport systems inner membrane component  33.67 
 
 
236 aa  88.6  8e-17  Salmonella enterica subsp. enterica serovar Agona str. SL483  Bacteria  normal  0.122529  n/a   
 
 
-
 
NC_011353  ECH74115_3255  ABC transporter, quaternary amine uptake (QAT) family, permease protein  33.67 
 
 
385 aa  88.6  9e-17  Escherichia coli O157:H7 str. EC4115  Bacteria  normal  hitchhiker  0.000687244 
 
 
-
 
NC_013172  Bfae_30020  ABC-type proline/glycine betaine transport system, permease component  35.45 
 
 
223 aa  87.8  1e-16  Brachybacterium faecium DSM 4810  Bacteria  normal  0.115362  n/a   
 
 
-
 
NC_009632  SaurJH1_2522  binding-protein-dependent transport systems inner membrane component  30.85 
 
 
211 aa  88.2  1e-16  Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  0.241712  n/a   
 
 
-
 
NC_010003  Pmob_1125  binding-protein-dependent transport systems inner membrane component  29.21 
 
 
218 aa  88.2  1e-16  Petrotoga mobilis SJ95  Bacteria  normal  n/a   
 
 
-
 
NC_010003  Pmob_1127  binding-protein-dependent transport systems inner membrane component  32.65 
 
 
216 aa  88.2  1e-16  Petrotoga mobilis SJ95  Bacteria  normal  0.721959  n/a   
 
 
-
 
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