More than 300 homologs were found in PanDaTox collection
for query gene Mesil_1100 on replicon NC_014212
Organism: Meiothermus silvanus DSM 9946



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_014212  Mesil_1100  two component transcriptional regulator, winged helix family  100 
 
 
224 aa  443  1e-123  Meiothermus silvanus DSM 9946  Bacteria  normal  0.602411  normal 
 
 
-
 
NC_013946  Mrub_2805  two component transcriptional regulator, winged helix family  87.05 
 
 
224 aa  394  1e-109  Meiothermus ruber DSM 1279  Bacteria  normal  normal  0.244907 
 
 
-
 
NC_008025  Dgeo_0195  two component transcriptional regulator  60.09 
 
 
222 aa  276  2e-73  Deinococcus geothermalis DSM 11300  Bacteria  normal  normal  0.304768 
 
 
-
 
NC_008025  Dgeo_2149  two component transcriptional regulator  58.26 
 
 
221 aa  252  4.0000000000000004e-66  Deinococcus geothermalis DSM 11300  Bacteria  normal  normal 
 
 
-
 
NC_008025  Dgeo_2318  two component transcriptional regulator  50.68 
 
 
225 aa  197  1.0000000000000001e-49  Deinococcus geothermalis DSM 11300  Bacteria  normal  0.642935  normal 
 
 
-
 
NC_013946  Mrub_1103  two component transcriptional regulator, winged helix family  49.32 
 
 
227 aa  195  4.0000000000000005e-49  Meiothermus ruber DSM 1279  Bacteria  normal  normal 
 
 
-
 
NC_014212  Mesil_2637  two component transcriptional regulator, winged helix family  50.23 
 
 
227 aa  195  4.0000000000000005e-49  Meiothermus silvanus DSM 9946  Bacteria  normal  normal 
 
 
-
 
NC_013525  Tter_1435  two component transcriptional regulator, winged helix family  45.7 
 
 
233 aa  181  7e-45  Thermobaculum terrenum ATCC BAA-798  Bacteria  n/a    n/a   
 
 
-
 
NC_009972  Haur_2799  two component transcriptional regulator  46.19 
 
 
236 aa  181  8.000000000000001e-45  Herpetosiphon aurantiacus ATCC 23779  Bacteria  unclonable  0.000000368356  n/a   
 
 
-
 
NC_011729  PCC7424_2242  two component transcriptional regulator, winged helix family  42.27 
 
 
224 aa  179  2.9999999999999997e-44  Cyanothece sp. PCC 7424  Bacteria  n/a    normal  0.415885 
 
 
-
 
NC_011884  Cyan7425_3411  two component transcriptional regulator, winged helix family  45.91 
 
 
224 aa  177  1e-43  Cyanothece sp. PCC 7425  Bacteria  normal  0.591115  normal 
 
 
-
 
NC_007413  Ava_0615  two component transcriptional regulator  43.18 
 
 
228 aa  176  3e-43  Anabaena variabilis ATCC 29413  Bacteria  normal  0.0841359  normal  0.719107 
 
 
-
 
NC_009767  Rcas_2487  two component transcriptional regulator  45.29 
 
 
224 aa  176  3e-43  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.431556  normal 
 
 
-
 
NC_009523  RoseRS_2290  two component transcriptional regulator  44.84 
 
 
224 aa  175  5e-43  Roseiflexus sp. RS-1  Bacteria  normal  normal 
 
 
-
 
NC_010320  Teth514_0588  two component transcriptional regulator  43.89 
 
 
227 aa  174  8e-43  Thermoanaerobacter sp. X514  Bacteria  unclonable  0.000000000451147  n/a   
 
 
-
 
NC_008148  Rxyl_3017  two component transcriptional regulator  47.49 
 
 
225 aa  174  9.999999999999999e-43  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  n/a   
 
 
-
 
NC_010552  BamMC406_3349  two component heavy metal response transcriptional regulator  42.53 
 
 
223 aa  172  2.9999999999999996e-42  Burkholderia ambifaria MC40-6  Bacteria  normal  normal 
 
 
-
 
NC_008391  Bamb_5186  two component heavy metal response transcriptional regulator  42.08 
 
 
223 aa  172  3.9999999999999995e-42  Burkholderia ambifaria AMMD  Bacteria  normal  normal 
 
 
-
 
NC_013216  Dtox_3055  two component transcriptional regulator, winged helix family  42.15 
 
 
227 aa  172  5e-42  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  0.703147  hitchhiker  0.000223036 
 
 
-
 
NC_008699  Noca_0312  response regulator receiver  42.92 
 
 
233 aa  171  6.999999999999999e-42  Nocardioides sp. JS614  Bacteria  normal  0.0102436  n/a   
 
 
-
 
NC_013517  Sterm_2324  two component transcriptional regulator, winged helix family  41.36 
 
 
223 aa  171  7.999999999999999e-42  Sebaldella termitidis ATCC 33386  Bacteria  normal  0.237639  n/a   
 
 
-
 
NC_012034  Athe_1456  two component transcriptional regulator, winged helix family  42.27 
 
 
223 aa  170  1e-41  Anaerocellum thermophilum DSM 6725  Bacteria  decreased coverage  0.000183373  n/a   
 
 
-
 
NC_007514  Cag_0440  two component transcriptional regulator  43.18 
 
 
225 aa  169  5e-41  Chlorobium chlorochromatii CaD3  Bacteria  normal  0.747409  n/a   
 
 
-
 
NC_011661  Dtur_1237  two component transcriptional regulator, winged helix family  42.67 
 
 
232 aa  167  8e-41  Dictyoglomus turgidum DSM 6724  Bacteria  normal  n/a   
 
 
-
 
NC_011725  BCB4264_A3169  regulatory protein VanR  43.05 
 
 
229 aa  167  1e-40  Bacillus cereus B4264  Bacteria  normal  0.16404  n/a   
 
 
-
 
NC_008392  Bamb_5988  two component heavy metal response transcriptional regulator  42.15 
 
 
225 aa  167  1e-40  Burkholderia ambifaria AMMD  Bacteria  normal  normal 
 
 
-
 
NC_011661  Dtur_0154  two component transcriptional regulator, winged helix family  43.64 
 
 
220 aa  167  2e-40  Dictyoglomus turgidum DSM 6724  Bacteria  normal  0.443854  n/a   
 
 
-
 
NC_013595  Sros_5447  response regulator receiver protein  46.36 
 
 
228 aa  166  4e-40  Streptosporangium roseum DSM 43021  Bacteria  hitchhiker  0.00883739  normal  0.15212 
 
 
-
 
NC_010557  BamMC406_5744  two component heavy metal response transcriptional regulator  41.7 
 
 
225 aa  165  4e-40  Burkholderia ambifaria MC40-6  Bacteria  normal  0.0360294  normal  0.749662 
 
 
-
 
NC_010001  Cphy_0015  two component transcriptional regulator  42.22 
 
 
228 aa  165  5e-40  Clostridium phytofermentans ISDg  Bacteria  normal  n/a   
 
 
-
 
NC_007971  Rmet_5978  regulatory protein CzcR  43.12 
 
 
225 aa  164  6.9999999999999995e-40  Cupriavidus metallidurans CH34  Bacteria  hitchhiker  0.0000269255  normal  0.0723212 
 
 
-
 
NC_011831  Cagg_1351  two component transcriptional regulator, winged helix family  43.5 
 
 
225 aa  164  6.9999999999999995e-40  Chloroflexus aggregans DSM 9485  Bacteria  hitchhiker  0.00188361  unclonable  0.0000000206018 
 
 
-
 
NC_009953  Sare_4064  two component transcriptional regulator  41.7 
 
 
233 aa  164  8e-40  Salinispora arenicola CNS-205  Bacteria  normal  0.98903  normal  0.0666639 
 
 
-
 
NC_003909  BCE_2675  DNA-binding response regulator  40.62 
 
 
224 aa  164  1.0000000000000001e-39  Bacillus cereus ATCC 10987  Bacteria  normal  0.0180828  n/a   
 
 
-
 
NC_009483  Gura_1986  two component heavy metal response transcriptional regulator  43.24 
 
 
223 aa  164  1.0000000000000001e-39  Geobacter uraniireducens Rf4  Bacteria  normal  0.0566795  n/a   
 
 
-
 
NC_007298  Daro_2815  response regulator receiver:transcriptional regulatory protein, C-terminal  45.21 
 
 
218 aa  164  1.0000000000000001e-39  Dechloromonas aromatica RCB  Bacteria  normal  0.877458  normal 
 
 
-
 
NC_011830  Dhaf_1237  two component transcriptional regulator, winged helix family  42.92 
 
 
234 aa  164  1.0000000000000001e-39  Desulfitobacterium hafniense DCB-2  Bacteria  normal  0.178035  n/a   
 
 
-
 
NC_013441  Gbro_4233  response regulator receiver  46.61 
 
 
244 aa  163  2.0000000000000002e-39  Gordonia bronchialis DSM 43247  Bacteria  normal  n/a   
 
 
-
 
NC_011830  Dhaf_2231  two component transcriptional regulator, winged helix family  43.44 
 
 
226 aa  163  2.0000000000000002e-39  Desulfitobacterium hafniense DCB-2  Bacteria  normal  n/a   
 
 
-
 
NC_010512  Bcenmc03_6987  two component heavy metal response transcriptional regulator  41.7 
 
 
225 aa  163  2.0000000000000002e-39  Burkholderia cenocepacia MC0-3  Bacteria  normal  0.67799  normal  0.586494 
 
 
-
 
NC_010515  Bcenmc03_4106  two component heavy metal response transcriptional regulator  40.72 
 
 
223 aa  163  2.0000000000000002e-39  Burkholderia cenocepacia MC0-3  Bacteria  normal  normal  0.971428 
 
 
-
 
NC_011725  BCB4264_A2673  DNA-binding response regulator  40.62 
 
 
224 aa  163  2.0000000000000002e-39  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_010184  BcerKBAB4_2492  two component transcriptional regulator  40.62 
 
 
224 aa  163  2.0000000000000002e-39  Bacillus weihenstephanensis KBAB4  Bacteria  normal  0.22217  n/a   
 
 
-
 
NC_011060  Ppha_0994  two component transcriptional regulator, winged helix family  42.73 
 
 
227 aa  163  2.0000000000000002e-39  Pelodictyon phaeoclathratiforme BU-1  Bacteria  normal  0.337893  n/a   
 
 
-
 
NC_013385  Adeg_1028  two component transcriptional regulator, winged helix family  44.05 
 
 
237 aa  163  2.0000000000000002e-39  Ammonifex degensii KC4  Bacteria  normal  n/a   
 
 
-
 
NC_008060  Bcen_1505  two component heavy metal response transcriptional regulator  41.7 
 
 
225 aa  163  2.0000000000000002e-39  Burkholderia cenocepacia AU 1054  Bacteria  normal  0.228186  n/a   
 
 
-
 
NC_013441  Gbro_2604  response regulator receiver  46.61 
 
 
244 aa  163  2.0000000000000002e-39  Gordonia bronchialis DSM 43247  Bacteria  normal  0.88392  n/a   
 
 
-
 
NC_008544  Bcen2424_6324  two component heavy metal response transcriptional regulator  41.7 
 
 
225 aa  163  2.0000000000000002e-39  Burkholderia cenocepacia HI2424  Bacteria  normal  0.313253  normal 
 
 
-
 
NC_007492  Pfl01_3354  two component transcriptional regulator  42.34 
 
 
220 aa  162  3e-39  Pseudomonas fluorescens Pf0-1  Bacteria  normal  0.44436  normal 
 
 
-
 
NC_014248  Aazo_0389  winged helix family two component transcriptional regulator  42.15 
 
 
224 aa  162  3e-39  'Nostoc azollae' 0708  Bacteria  normal  0.667669  n/a   
 
 
-
 
NC_009380  Strop_3686  response regulator receiver  41.7 
 
 
233 aa  162  4.0000000000000004e-39  Salinispora tropica CNB-440  Bacteria  normal  normal 
 
 
-
 
NC_010682  Rpic_1760  two component heavy metal response transcriptional regulator, winged helix family  42.2 
 
 
225 aa  162  4.0000000000000004e-39  Ralstonia pickettii 12J  Bacteria  normal  0.133831  normal  0.402692 
 
 
-
 
NC_007802  Jann_2294  two component transcriptional regulator  41.18 
 
 
228 aa  162  4.0000000000000004e-39  Jannaschia sp. CCS1  Bacteria  normal  0.305192  normal 
 
 
-
 
NC_007952  Bxe_B1389  two component heavy metal response transcriptional regulator  40.81 
 
 
225 aa  162  4.0000000000000004e-39  Burkholderia xenovorans LB400  Bacteria  normal  0.717226  normal  0.091392 
 
 
-
 
NC_011126  HY04AAS1_1151  two component transcriptional regulator, winged helix family  38.53 
 
 
225 aa  162  4.0000000000000004e-39  Hydrogenobaculum sp. Y04AAS1  Bacteria  normal  n/a   
 
 
-
 
NC_013595  Sros_2839  response regulator receiver protein  44.84 
 
 
228 aa  162  5.0000000000000005e-39  Streptosporangium roseum DSM 43021  Bacteria  normal  0.0400316  normal  0.0390199 
 
 
-
 
NC_008061  Bcen_4757  two component heavy metal response transcriptional regulator  40.27 
 
 
223 aa  162  5.0000000000000005e-39  Burkholderia cenocepacia AU 1054  Bacteria  normal  0.0878196  n/a   
 
 
-
 
NC_008543  Bcen2424_3410  two component heavy metal response transcriptional regulator  40.27 
 
 
223 aa  162  5.0000000000000005e-39  Burkholderia cenocepacia HI2424  Bacteria  normal  normal 
 
 
-
 
NC_007604  Synpcc7942_1873  two component transcriptional regulator  40.27 
 
 
226 aa  161  6e-39  Synechococcus elongatus PCC 7942  Bacteria  normal  normal 
 
 
-
 
NC_009012  Cthe_3069  two component transcriptional regulator  39.74 
 
 
230 aa  161  6e-39  Clostridium thermocellum ATCC 27405  Bacteria  hitchhiker  0.0000000467461  n/a   
 
 
-
 
NC_009632  SaurJH1_1505  response regulator receiver  39.73 
 
 
219 aa  161  7e-39  Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  0.404603  n/a   
 
 
-
 
NC_009487  SaurJH9_1476  two component transcriptional regulator  39.73 
 
 
219 aa  161  7e-39  Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  n/a   
 
 
-
 
NC_009253  Dred_0759  two component transcriptional regulator  40.91 
 
 
223 aa  161  7e-39  Desulfotomaculum reducens MI-1  Bacteria  hitchhiker  0.00128917  n/a   
 
 
-
 
NC_010501  PputW619_3309  two component transcriptional regulator  44.24 
 
 
220 aa  161  7e-39  Pseudomonas putida W619  Bacteria  normal  normal 
 
 
-
 
NC_010184  BcerKBAB4_2313  two component transcriptional regulator  38.22 
 
 
228 aa  161  8.000000000000001e-39  Bacillus weihenstephanensis KBAB4  Bacteria  normal  0.0313786  n/a   
 
 
-
 
NC_010623  Bphy_3962  two component heavy metal response transcriptional regulator  42.01 
 
 
225 aa  161  8.000000000000001e-39  Burkholderia phymatum STM815  Bacteria  normal  normal 
 
 
-
 
NC_010803  Clim_1291  two component transcriptional regulator, winged helix family  42.73 
 
 
222 aa  161  9e-39  Chlorobium limicola DSM 245  Bacteria  normal  n/a   
 
 
-
 
NC_007492  Pfl01_0202  two component heavy metal response transcriptional regulator  41.7 
 
 
226 aa  161  9e-39  Pseudomonas fluorescens Pf0-1  Bacteria  normal  normal 
 
 
-
 
NC_009012  Cthe_1288  two component transcriptional regulator  39.55 
 
 
228 aa  161  9e-39  Clostridium thermocellum ATCC 27405  Bacteria  decreased coverage  0.00000000128008  n/a   
 
 
-
 
NC_010718  Nther_0984  two component transcriptional regulator, winged helix family  39.75 
 
 
246 aa  160  1e-38  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  normal  0.0723779 
 
 
-
 
NC_005957  BT9727_1191  response regulator  39.73 
 
 
223 aa  160  1e-38  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  n/a   
 
 
-
 
NC_010676  Bphyt_5224  two component heavy metal response transcriptional regulator, winged helix family  40.81 
 
 
225 aa  160  1e-38  Burkholderia phytofirmans PsJN  Bacteria  normal  0.57611  normal 
 
 
-
 
NC_006274  BCZK1193  response regulator  39.27 
 
 
223 aa  160  1e-38  Bacillus cereus E33L  Bacteria  normal  n/a   
 
 
-
 
NC_011205  SeD_A1171  transcriptional regulatory protein YedW  42.2 
 
 
226 aa  160  1e-38  Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853  Bacteria  normal  normal 
 
 
-
 
NC_007604  Synpcc7942_1453  two component transcriptional regulator  40.87 
 
 
244 aa  160  1e-38  Synechococcus elongatus PCC 7942  Bacteria  normal  0.952418  normal  0.0249242 
 
 
-
 
NC_011725  BCB4264_A1351  DNA-binding response regulator  39.27 
 
 
223 aa  160  1e-38  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_011773  BCAH820_1389  DNA-binding response regulator  39.27 
 
 
223 aa  160  1e-38  Bacillus cereus AH820  Bacteria  n/a    normal 
 
 
-
 
NC_002936  DET1058  DNA-binding response regulator  41.33 
 
 
227 aa  160  2e-38  Dehalococcoides ethenogenes 195  Bacteria  decreased coverage  0.000187393  n/a   
 
 
-
 
NC_003909  BCE_1413  DNA-binding response regulator  39.27 
 
 
223 aa  160  2e-38  Bacillus cereus ATCC 10987  Bacteria  normal  n/a   
 
 
-
 
NC_009674  Bcer98_1021  two component transcriptional regulator  39.27 
 
 
223 aa  159  2e-38  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  n/a   
 
 
-
 
NC_004116  SAG1625  DNA-binding response regulator CsrR  37.89 
 
 
229 aa  159  2e-38  Streptococcus agalactiae 2603V/R  Bacteria  normal  0.137799  n/a   
 
 
-
 
NC_010184  BcerKBAB4_0249  two component transcriptional regulator  39.21 
 
 
233 aa  160  2e-38  Bacillus weihenstephanensis KBAB4  Bacteria  normal  0.0382139  n/a   
 
 
-
 
NC_011772  BCG9842_B3993  DNA-binding response regulator  39.27 
 
 
223 aa  159  2e-38  Bacillus cereus G9842  Bacteria  normal  normal  0.910988 
 
 
-
 
NC_012791  Vapar_3559  two component heavy metal response transcriptional regulator, winged helix family  41.63 
 
 
225 aa  159  2e-38  Variovorax paradoxus S110  Bacteria  normal  0.710681  n/a   
 
 
-
 
NC_010501  PputW619_3019  two component transcriptional regulator  44.24 
 
 
220 aa  160  2e-38  Pseudomonas putida W619  Bacteria  normal  0.933394  normal 
 
 
-
 
NC_013411  GYMC61_1696  two component transcriptional regulator, winged helix family  41.36 
 
 
224 aa  160  2e-38  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_011658  BCAH187_A1453  DNA-binding response regulator  39.27 
 
 
223 aa  160  2e-38  Bacillus cereus AH187  Bacteria  normal  n/a   
 
 
-
 
NC_010070  Bmul_6295  two component heavy metal response transcriptional regulator  40.27 
 
 
223 aa  160  2e-38  Burkholderia multivorans ATCC 17616  Bacteria  normal  0.803537  normal  0.219108 
 
 
-
 
NC_003909  BCE_0294  DNA-binding response regulator  38.77 
 
 
233 aa  159  3e-38  Bacillus cereus ATCC 10987  Bacteria  normal  n/a   
 
 
-
 
NC_011884  Cyan7425_1115  two component transcriptional regulator, winged helix family  40.87 
 
 
243 aa  159  3e-38  Cyanothece sp. PCC 7425  Bacteria  normal  0.0950226  normal 
 
 
-
 
NC_011772  BCG9842_B5021  DNA-binding response regulator  38.77 
 
 
233 aa  159  3e-38  Bacillus cereus G9842  Bacteria  normal  0.0330449  normal 
 
 
-
 
NC_005945  BAS0256  DNA-binding response regulator  39.21 
 
 
233 aa  159  3e-38  Bacillus anthracis str. Sterne  Bacteria  normal  n/a   
 
 
-
 
NC_006274  BCZK0245  response regulator  39.21 
 
 
233 aa  159  3e-38  Bacillus cereus E33L  Bacteria  normal  n/a   
 
 
-
 
NC_011080  SNSL254_A1191  transcriptional regulatory protein YedW  41.74 
 
 
226 aa  159  3e-38  Salmonella enterica subsp. enterica serovar Newport str. SL254  Bacteria  normal  normal 
 
 
-
 
NC_011725  BCB4264_A0303  DNA-binding response regulator  38.77 
 
 
233 aa  159  3e-38  Bacillus cereus B4264  Bacteria  normal  0.0610099  n/a   
 
 
-
 
NC_007530  GBAA_0271  DNA-binding response regulator  39.21 
 
 
233 aa  159  3e-38  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  0.439326  n/a   
 
 
-
 
NC_010002  Daci_1713  two component heavy metal response transcriptional regulator  42.04 
 
 
227 aa  159  3e-38  Delftia acidovorans SPH-1  Bacteria  normal  normal  0.535279 
 
 
-
 
NC_007973  Rmet_1751  two component heavy metal response transcriptional regulator  41.89 
 
 
224 aa  159  3e-38  Cupriavidus metallidurans CH34  Bacteria  normal  normal  0.0784096 
 
 
-
 
NC_011898  Ccel_1892  two component transcriptional regulator, winged helix family  40.45 
 
 
228 aa  159  3e-38  Clostridium cellulolyticum H10  Bacteria  hitchhiker  0.0000392  n/a   
 
 
-
 
NC_013216  Dtox_1554  two component transcriptional regulator, winged helix family  39.29 
 
 
229 aa  159  3e-38  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  hitchhiker  0.00709514 
 
 
-
 
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