48 homologs were found in PanDaTox collection
for query gene CNC05080 on replicon NC_006685
Organism: Cryptococcus neoformans var. neoformans JEC21



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_006685  CNC05080  hydroxymethylglutaryl-CoA synthase, putative  100 
 
 
498 aa  1031    Cryptococcus neoformans var. neoformans JEC21  Eukaryota  normal  0.0146937  n/a   
 
 
-
 
NC_006692  CNG02670  conserved hypothetical protein  81.93 
 
 
492 aa  863    Cryptococcus neoformans var. neoformans JEC21  Eukaryota  normal  0.250048  n/a   
 
 
-
 
BN001303  ANIA_04923  hydroxymethylglutaryl-CoA synthase, expressed (Eurofung)  46.95 
 
 
459 aa  474  1e-132  Aspergillus nidulans FGSC A4  Eukaryota  decreased coverage  0.000140052  normal  0.183137 
 
 
-
 
NC_009043  PICST_83020  predicted protein  42.68 
 
 
447 aa  400  9.999999999999999e-111  Scheffersomyces stipitis CBS 6054  Eukaryota  normal  normal  0.203181 
 
 
-
 
NC_011695  PHATRDRAFT_16649  predicted protein  40.36 
 
 
461 aa  323  4e-87  Phaeodactylum tricornutum CCAP 1055/1  Eukaryota  normal  0.24052  n/a   
 
 
-
 
NC_010085  Nmar_0828  hydroxymethylglutaryl-CoA synthase  26.54 
 
 
464 aa  122  1.9999999999999998e-26  Nitrosopumilus maritimus SCM1  Archaea  n/a    normal  0.0208074 
 
 
-
 
NC_013743  Htur_2310  Hydroxymethylglutaryl-CoA synthase  27.31 
 
 
445 aa  112  1.0000000000000001e-23  Haloterrigena turkmenica DSM 5511  Archaea  n/a    n/a   
 
 
-
 
NC_012029  Hlac_2313  Hydroxymethylglutaryl-coenzyme A synthase domain protein  25.58 
 
 
447 aa  107  4e-22  Halorubrum lacusprofundi ATCC 49239  Archaea  normal  0.859835  normal 
 
 
-
 
NC_013515  Smon_1291  hydroxymethylglutaryl-CoA synthase  25.56 
 
 
383 aa  106  8e-22  Streptobacillus moniliformis DSM 12112  Bacteria  n/a    n/a   
 
 
-
 
NC_013922  Nmag_0401  Hydroxymethylglutaryl-CoA synthase  24.94 
 
 
445 aa  106  8e-22  Natrialba magadii ATCC 43099  Archaea  normal  n/a   
 
 
-
 
NC_013158  Huta_2766  Hydroxymethylglutaryl-CoA synthase  36.08 
 
 
444 aa  104  3e-21  Halorhabdus utahensis DSM 12940  Archaea  normal  n/a   
 
 
-
 
NC_013202  Hmuk_1739  Hydroxymethylglutaryl-CoA synthase  24.56 
 
 
447 aa  102  2e-20  Halomicrobium mukohataei DSM 12286  Archaea  normal  normal 
 
 
-
 
NC_007520  Tcr_1719  hydroxymethylglutaryl-coenzyme A synthase  23.97 
 
 
389 aa  99.4  1e-19  Thiomicrospira crunogena XCL-2  Bacteria  normal  0.396765  n/a   
 
 
-
 
NC_011887  Mnod_8252  hydroxymethylglutaryl-CoA synthase  30.97 
 
 
396 aa  95.5  2e-18  Methylobacterium nodulans ORS 2060  Bacteria  normal  0.112958  n/a   
 
 
-
 
NC_013440  Hoch_4396  Hydroxymethylglutaryl-CoA synthase  28.57 
 
 
369 aa  91.7  3e-17  Haliangium ochraceum DSM 14365  Bacteria  normal  0.0133862  normal 
 
 
-
 
NC_013131  Caci_2595  Hydroxymethylglutaryl-CoA synthase  24.1 
 
 
413 aa  86.7  9e-16  Catenulispora acidiphila DSM 44928  Bacteria  normal  normal 
 
 
-
 
NC_013721  HMPREF0424_0359  putative hydroxymethylglutaryl-CoA synthase  31.82 
 
 
437 aa  85.1  0.000000000000003  Gardnerella vaginalis 409-05  Bacteria  n/a    normal 
 
 
-
 
NC_002976  SERP2122  hydroxymethylglutaryl-CoA synthase  21.79 
 
 
388 aa  83.2  0.00000000000001  Staphylococcus epidermidis RP62A  Bacteria  normal  n/a   
 
 
-
 
NC_011884  Cyan7425_2884  Hydroxymethylglutaryl-coenzyme A synthase domain protein  23.21 
 
 
419 aa  82  0.00000000000002  Cyanothece sp. PCC 7425  Bacteria  normal  normal  0.614903 
 
 
-
 
NC_008527  LACR_1666  hydroxymethylglutaryl-CoA synthase  28.25 
 
 
384 aa  80.9  0.00000000000004  Lactococcus lactis subsp. cremoris SK11  Bacteria  normal  0.696762  n/a   
 
 
-
 
NC_008530  LGAS_1372  3-hydroxy-3-methylglutaryl CoA synthase  27.27 
 
 
387 aa  79.7  0.0000000000001  Lactobacillus gasseri ATCC 33323  Bacteria  normal  0.998569  hitchhiker  0.00000000102593 
 
 
-
 
NC_013132  Cpin_5295  Hydroxymethylglutaryl-CoA synthase  22.7 
 
 
417 aa  79.7  0.0000000000001  Chitinophaga pinensis DSM 2588  Bacteria  normal  0.0778158  normal  0.248767 
 
 
-
 
NC_009487  SaurJH9_2569  hydroxymethylglutaryl-CoA synthase  26.74 
 
 
388 aa  75.9  0.000000000002  Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  n/a   
 
 
-
 
NC_009632  SaurJH1_2622  hydroxymethylglutaryl-CoA synthase  26.74 
 
 
388 aa  75.9  0.000000000002  Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  n/a   
 
 
-
 
NC_007650  BTH_II1670  polyketide biosynthesis protein  24.03 
 
 
418 aa  74.3  0.000000000004  Burkholderia thailandensis E264  Bacteria  normal  0.130518  n/a   
 
 
-
 
NC_013131  Caci_2601  Hydroxymethylglutaryl-coenzyme A synthase domain protein  21.87 
 
 
424 aa  73.9  0.000000000007  Catenulispora acidiphila DSM 44928  Bacteria  normal  0.0233973  normal  0.914531 
 
 
-
 
NC_009727  CBUD_1931  hydroxymethylglutaryl-CoA synthase family protein  22.75 
 
 
412 aa  73.2  0.00000000001  Coxiella burnetii Dugway 5J108-111  Bacteria  normal  0.808673  n/a   
 
 
-
 
NC_008531  LEUM_1184  hydroxymethylglutaryl-CoA synthase  26.62 
 
 
385 aa  69.3  0.0000000001  Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293  Bacteria  normal  0.298537  n/a   
 
 
-
 
NC_008528  OEOE_0968  hydroxymethylglutaryl-CoA synthase  28 
 
 
389 aa  68.2  0.0000000003  Oenococcus oeni PSU-1  Bacteria  normal  0.032504  n/a   
 
 
-
 
NC_012880  Dd703_1418  Hydroxymethylglutaryl-CoA synthase  24.24 
 
 
420 aa  68.6  0.0000000003  Dickeya dadantii Ech703  Bacteria  normal  n/a   
 
 
-
 
NC_008532  STER_0621  hydroxymethylglutaryl-CoA synthase (HMG-CoA synthase)  24.26 
 
 
391 aa  66.6  0.0000000009  Streptococcus thermophilus LMD-9  Bacteria  hitchhiker  0.000102903  n/a   
 
 
-
 
NC_009441  Fjoh_0678  hydroxymethylglutaryl-CoA synthase  27.06 
 
 
453 aa  66.6  0.000000001  Flavobacterium johnsoniae UW101  Bacteria  normal  0.0215835  n/a   
 
 
-
 
NC_009513  Lreu_0676  hydroxymethylglutaryl-CoA synthase  30.24 
 
 
385 aa  66.2  0.000000001  Lactobacillus reuteri DSM 20016  Bacteria  hitchhiker  0.000000283469  n/a   
 
 
-
 
NC_006349  BMAA1212  polyketide biosynthesis protein, interruption-N  22.25 
 
 
389 aa  64.3  0.000000005  Burkholderia mallei ATCC 23344  Bacteria  normal  0.737994  n/a   
 
 
-
 
NC_009075  BURPS668_A1470  putative polyketide biosynthesis protein pksG  22.13 
 
 
419 aa  62.8  0.00000001  Burkholderia pseudomallei 668  Bacteria  normal  0.0349844  n/a   
 
 
-
 
NC_009078  BURPS1106A_A1384  putative polyketide biosynthesis protein pksG  22.13 
 
 
419 aa  62.8  0.00000001  Burkholderia pseudomallei 1106a  Bacteria  normal  n/a   
 
 
-
 
NC_007435  BURPS1710b_A2613  putative hydroxymethylglutaryl-coenzyme A synthase  22.13 
 
 
419 aa  62.8  0.00000001  Burkholderia pseudomallei 1710b  Bacteria  normal  0.457692  n/a   
 
 
-
 
NC_004116  SAG1316  HMG-CoA synthase  27.64 
 
 
390 aa  62  0.00000002  Streptococcus agalactiae 2603V/R  Bacteria  normal  0.717019  n/a   
 
 
-
 
NC_011728  BbuZS7_0703  hydroxymethylglutaryl-CoA synthase  29.08 
 
 
407 aa  59.7  0.0000001  Borrelia burgdorferi ZS7  Bacteria  normal  n/a   
 
 
-
 
NC_010465  YPK_2608  hydroxymethylglutaryl-coenzyme A synthase  29.05 
 
 
412 aa  55.8  0.000002  Yersinia pseudotuberculosis YPIII  Bacteria  normal  n/a   
 
 
-
 
NC_010159  YpAngola_A2969  putative hydroxymethylglutaryl-coenzyme A synthase  29.05 
 
 
397 aa  55.8  0.000002  Yersinia pestis Angola  Bacteria  normal  0.763389  hitchhiker  0.0000211937 
 
 
-
 
NC_009708  YpsIP31758_2518  putative hydroxymethylglutaryl-coenzyme A synthase  29.05 
 
 
412 aa  55.8  0.000002  Yersinia pseudotuberculosis IP 31758  Bacteria  normal  n/a   
 
 
-
 
NC_013440  Hoch_1179  Hydroxymethylglutaryl-coenzyme A synthase domain protein  25.33 
 
 
407 aa  54.7  0.000004  Haliangium ochraceum DSM 14365  Bacteria  normal  normal 
 
 
-
 
NC_011671  PHATR_33278  predicted protein  71.79 
 
 
321 aa  52.4  0.00002  Phaeodactylum tricornutum CCAP 1055/1  Eukaryota  normal  n/a   
 
 
-
 
NC_011832  Mpal_2510  hypothetical protein  30 
 
 
350 aa  47.8  0.0005  Methanosphaerula palustris E1-9c  Archaea  normal  0.507027  normal  0.708898 
 
 
-
 
NC_008553  Mthe_1390  hypothetical protein  28.36 
 
 
345 aa  47  0.0008  Methanosaeta thermophila PT  Archaea  normal  n/a   
 
 
-
 
NC_008701  Pisl_0811  hypothetical protein  26.83 
 
 
350 aa  47  0.0009  Pyrobaculum islandicum DSM 4184  Archaea  normal  0.836821  hitchhiker  0.000111453 
 
 
-
 
NC_009712  Mboo_0157  hypothetical protein  27.13 
 
 
350 aa  47  0.0009  Candidatus Methanoregula boonei 6A8  Archaea  normal  normal 
 
 
-
 
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