63 homologs were found in PanDaTox collection
for query gene AFE_0041 on replicon NC_011761
Organism: Acidithiobacillus ferrooxidans ATCC 23270



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_011206  Lferr_0042  C4-dicarboxylate transporter/malic acid transport protein  99.74 
 
 
402 aa  761    Acidithiobacillus ferrooxidans ATCC 53993  Bacteria  normal  0.120445  normal 
 
 
-
 
NC_011761  AFE_0041  C4-dicarboxylate transporter/malic acid transport protein  100 
 
 
385 aa  762    Acidithiobacillus ferrooxidans ATCC 23270  Bacteria  normal  0.299856  n/a   
 
 
-
 
NC_011761  AFE_1992  C4-dicarboxylate transporter/malic acid transport protein  58.14 
 
 
400 aa  450  1e-125  Acidithiobacillus ferrooxidans ATCC 23270  Bacteria  normal  n/a   
 
 
-
 
NC_011206  Lferr_1661  C4-dicarboxylate transporter/malic acid transport protein  58.14 
 
 
400 aa  450  1e-125  Acidithiobacillus ferrooxidans ATCC 53993  Bacteria  normal  normal  0.431835 
 
 
-
 
NC_011126  HY04AAS1_1047  C4-dicarboxylate transporter/malic acid transport protein  48.51 
 
 
387 aa  357  1.9999999999999998e-97  Hydrogenobaculum sp. Y04AAS1  Bacteria  decreased coverage  0.000000000418188  n/a   
 
 
-
 
NC_004578  PSPTO_4613  C4-dicarboxylate transporter/malic acid transport protein  47.37 
 
 
389 aa  318  7.999999999999999e-86  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  0.522364  n/a   
 
 
-
 
NC_007005  Psyr_1479  C4-dicarboxylate transporter/malic acid transport protein  47.37 
 
 
389 aa  318  1e-85  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  0.805909  normal 
 
 
-
 
NC_010581  Bind_2472  C4-dicarboxylate transporter/malic acid transport protein  49.59 
 
 
419 aa  314  9.999999999999999e-85  Beijerinckia indica subsp. indica ATCC 9039  Bacteria  normal  normal 
 
 
-
 
NC_007492  Pfl01_1664  C4-dicarboxylate transporter/malic acid transport protein  50.56 
 
 
383 aa  313  1.9999999999999998e-84  Pseudomonas fluorescens Pf0-1  Bacteria  normal  0.537362  normal  0.0255572 
 
 
-
 
NC_007650  BTH_II1616  C4-dicarboxylate transporter/malic acid transport protein, putative  45.73 
 
 
381 aa  306  5.0000000000000004e-82  Burkholderia thailandensis E264  Bacteria  normal  0.195431  n/a   
 
 
-
 
NC_009439  Pmen_0457  C4-dicarboxylate transporter/malic acid transport protein  47.61 
 
 
384 aa  296  4e-79  Pseudomonas mendocina ymp  Bacteria  normal  normal 
 
 
-
 
NC_004578  PSPTO_3541  C4-dicarboxylate transporter/malic acid transport protein  47.11 
 
 
386 aa  286  5.999999999999999e-76  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  0.123279  n/a   
 
 
-
 
NC_007005  Psyr_3313  C4-dicarboxylate transporter/malic acid transport protein  46.39 
 
 
386 aa  283  4.0000000000000003e-75  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  normal  0.43165 
 
 
-
 
NC_010552  BamMC406_4643  C4-dicarboxylate transporter/malic acid transport protein  48.6 
 
 
383 aa  280  4e-74  Burkholderia ambifaria MC40-6  Bacteria  normal  normal 
 
 
-
 
NC_009484  Acry_2615  C4-dicarboxylate transporter/malic acid transport protein  49.72 
 
 
429 aa  276  4e-73  Acidiphilium cryptum JF-5  Bacteria  normal  0.298091  n/a   
 
 
-
 
NC_011666  Msil_3232  C4-dicarboxylate transporter/malic acid transport protein  48.33 
 
 
382 aa  262  8e-69  Methylocella silvestris BL2  Bacteria  n/a    hitchhiker  0.00415956 
 
 
-
 
NC_008010  Dgeo_2839  C4-dicarboxylate transporter/malic acid transport protein  47.53 
 
 
378 aa  256  3e-67  Deinococcus geothermalis DSM 11300  Bacteria  normal  n/a   
 
 
-
 
BN001306  ANIA_09133  malate permease (Eurofung)  36.07 
 
 
361 aa  209  5e-53  Aspergillus nidulans FGSC A4  Eukaryota  normal  0.0625395  normal  0.622615 
 
 
-
 
NC_008537  Arth_4391  C4-dicarboxylate transporter/malic acid transport protein  34.08 
 
 
395 aa  177  4e-43  Arthrobacter sp. FB24  Bacteria  normal  n/a   
 
 
-
 
NC_013124  Afer_0433  C4-dicarboxylate transporter/malic acid transport protein  33.92 
 
 
366 aa  164  3e-39  Acidimicrobium ferrooxidans DSM 10331  Bacteria  normal  n/a   
 
 
-
 
NC_013947  Snas_5153  C4-dicarboxylate transporter/malic acid transport protein  33.33 
 
 
435 aa  160  4e-38  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  normal 
 
 
-
 
NC_008726  Mvan_4384  C4-dicarboxylate transporter/malic acid transport protein  30.85 
 
 
374 aa  150  3e-35  Mycobacterium vanbaalenii PYR-1  Bacteria  normal  normal 
 
 
-
 
NC_009338  Mflv_2282  C4-dicarboxylate transporter/malic acid transport protein  30.43 
 
 
404 aa  150  5e-35  Mycobacterium gilvum PYR-GCK  Bacteria  normal  normal  0.522283 
 
 
-
 
NC_013205  Aaci_2914  C4-dicarboxylate transporter/malic acid transport protein  31.08 
 
 
369 aa  144  3e-33  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  n/a   
 
 
-
 
NC_003910  CPS_3436  C4-dicarboxylate transporter/malic acid transport protein  31.58 
 
 
375 aa  140  4.999999999999999e-32  Colwellia psychrerythraea 34H  Bacteria  normal  n/a   
 
 
-
 
BN001304  ANIA_11016  malic acid transport protein, putative (AFU_orthologue; AFUA_4G09410)  28.95 
 
 
388 aa  139  6e-32  Aspergillus nidulans FGSC A4  Eukaryota  normal  normal  0.522177 
 
 
-
 
NC_006670  CNA05110  sulfite transporter, putative  29.9 
 
 
517 aa  135  1.9999999999999998e-30  Cryptococcus neoformans var. neoformans JEC21  Eukaryota  normal  n/a   
 
 
-
 
NC_009901  Spea_1117  C4-dicarboxylate transporter/malic acid transport protein  28.46 
 
 
385 aa  130  3e-29  Shewanella pealeana ATCC 700345  Bacteria  normal  n/a   
 
 
-
 
NC_014158  Tpau_2094  C4-dicarboxylate transporter/malic acid transport protein  30.16 
 
 
395 aa  127  4.0000000000000003e-28  Tsukamurella paurometabola DSM 20162  Bacteria  normal  0.113103  n/a   
 
 
-
 
NC_007298  Daro_0680  C4-dicarboxylate transporter/malic acid transport protein  28.41 
 
 
346 aa  124  2e-27  Dechloromonas aromatica RCB  Bacteria  normal  normal 
 
 
-
 
NC_013216  Dtox_3375  C4-dicarboxylate transporter/malic acid transport protein  25.56 
 
 
353 aa  115  8.999999999999998e-25  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  0.646539  normal 
 
 
-
 
NC_009043  PICST_30900  predicted protein  25.89 
 
 
449 aa  102  1e-20  Scheffersomyces stipitis CBS 6054  Eukaryota  normal  0.192917  normal  0.324549 
 
 
-
 
NC_009043  PICST_30901  predicted protein  28.31 
 
 
433 aa  100  4e-20  Scheffersomyces stipitis CBS 6054  Eukaryota  normal  normal  0.314839 
 
 
-
 
NC_013441  Gbro_4610  C4-dicarboxylate transporter/malic acid transport protein  28.97 
 
 
374 aa  98.6  2e-19  Gordonia bronchialis DSM 43247  Bacteria  normal  0.174728  n/a   
 
 
-
 
NC_009043  PICST_44239  predicted protein  26.49 
 
 
373 aa  97.4  4e-19  Scheffersomyces stipitis CBS 6054  Eukaryota  normal  normal  0.182141 
 
 
-
 
BN001307  ANIA_01472  C4-dicarboxylate transporter/malic acid transport protein, putative (AFU_orthologue; AFUA_8G04630)  22.54 
 
 
395 aa  95.5  2e-18  Aspergillus nidulans FGSC A4  Eukaryota  hitchhiker  0.00510243  normal  0.213682 
 
 
-
 
NC_013739  Cwoe_4856  C4-dicarboxylate transporter/malic acid transport protein  27.49 
 
 
363 aa  79.7  0.00000000000008  Conexibacter woesei DSM 14684  Bacteria  normal  0.0594836  normal 
 
 
-
 
BN001304  ANIA_07797  C4-dicarboxylate transporter/malic acid transport protein, putative (AFU_orthologue; AFUA_2G17660)  22.16 
 
 
375 aa  76.3  0.0000000000009  Aspergillus nidulans FGSC A4  Eukaryota  normal  normal  0.0796042 
 
 
-
 
NC_013926  Aboo_0404  C4-dicarboxylate transporter/malic acid transport protein  21.19 
 
 
343 aa  72  0.00000000001  Aciduliprofundum boonei T469  Archaea  normal  n/a   
 
 
-
 
NC_013158  Huta_1807  C4-dicarboxylate transporter/malic acid transport protein  26.72 
 
 
373 aa  66.6  0.0000000008  Halorhabdus utahensis DSM 12940  Archaea  normal  n/a   
 
 
-
 
NC_011830  Dhaf_0897  C4-dicarboxylate transporter/malic acid transport protein  23.2 
 
 
384 aa  66.2  0.0000000008  Desulfitobacterium hafniense DCB-2  Bacteria  normal  0.0526316  n/a   
 
 
-
 
NC_012034  Athe_2212  C4-dicarboxylate transporter/malic acid transport protein  20.06 
 
 
347 aa  63.5  0.000000006  Anaerocellum thermophilum DSM 6725  Bacteria  hitchhiker  0.000186594  n/a   
 
 
-
 
NC_006682  CNM00310  conserved hypothetical protein  25.2 
 
 
382 aa  58.5  0.0000002  Cryptococcus neoformans var. neoformans JEC21  Eukaryota  decreased coverage  0.00875379  n/a   
 
 
-
 
NC_007908  Rfer_4140  C4-dicarboxylate transporter/malic acid transport protein  24.46 
 
 
374 aa  57.8  0.0000003  Rhodoferax ferrireducens T118  Bacteria  normal  n/a   
 
 
-
 
NC_009043  PICST_30899  predicted protein  23.91 
 
 
438 aa  57.8  0.0000004  Scheffersomyces stipitis CBS 6054  Eukaryota  normal  0.341718  normal  0.766697 
 
 
-
 
NC_007484  Noc_0077  C4-dicarboxylate transporter/malic acid transport protein  24.21 
 
 
360 aa  57.4  0.0000004  Nitrosococcus oceani ATCC 19707  Bacteria  normal  n/a   
 
 
-
 
NC_007964  Nham_3443  C4-dicarboxylate transporter/malic acid transport protein  23.26 
 
 
357 aa  57.4  0.0000004  Nitrobacter hamburgensis X14  Bacteria  normal  0.288016  n/a   
 
 
-
 
NC_013946  Mrub_2878  C4-dicarboxylate transporter/malic acid transport protein  28.43 
 
 
356 aa  55.5  0.000002  Meiothermus ruber DSM 1279  Bacteria  normal  normal 
 
 
-
 
NC_007484  Noc_0542  hypothetical protein  26.15 
 
 
239 aa  55.1  0.000002  Nitrosococcus oceani ATCC 19707  Bacteria  normal  n/a   
 
 
-
 
NC_007348  Reut_B4485  C4-dicarboxylate transporter/malic acid transport protein  22.78 
 
 
331 aa  54.3  0.000003  Ralstonia eutropha JMP134  Bacteria  normal  n/a   
 
 
-
 
NC_007406  Nwi_0780  C4-dicarboxylate transporter/malic acid transport protein  23.6 
 
 
357 aa  54.7  0.000003  Nitrobacter winogradskyi Nb-255  Bacteria  normal  0.439513  normal 
 
 
-
 
NC_013422  Hneap_0262  C4-dicarboxylate transporter/malic acid transport protein  22.67 
 
 
326 aa  53.5  0.000006  Halothiobacillus neapolitanus c2  Bacteria  normal  0.490453  n/a   
 
 
-
 
NC_008599  CFF8240_0914  C4-dicarboxylate transporter/malic acid transport protein  22.53 
 
 
357 aa  52  0.00002  Campylobacter fetus subsp. fetus 82-40  Bacteria  normal  0.120937  n/a   
 
 
-
 
NC_011059  Paes_1250  C4-dicarboxylate transporter/malic acid transport protein  20.63 
 
 
339 aa  50.4  0.00006  Prosthecochloris aestuarii DSM 271  Bacteria  normal  normal  0.618998 
 
 
-
 
NC_013235  Namu_3523  C4-dicarboxylate transporter/malic acid transport protein  24.46 
 
 
366 aa  48.1  0.0002  Nakamurella multipartita DSM 44233  Bacteria  hitchhiker  0.00371301  normal  0.143874 
 
 
-
 
NC_008639  Cpha266_1002  C4-dicarboxylate transporter/malic acid transport protein  20.45 
 
 
326 aa  47  0.0005  Chlorobium phaeobacteroides DSM 266  Bacteria  normal  n/a   
 
 
-
 
NC_013235  Namu_4602  C4-dicarboxylate transporter/malic acid transport protein  24.44 
 
 
357 aa  47  0.0006  Nakamurella multipartita DSM 44233  Bacteria  normal  normal  0.681396 
 
 
-
 
NC_007347  Reut_A2607  C4-dicarboxylate transporter/malic acid transport protein  21.31 
 
 
329 aa  45.4  0.002  Ralstonia eutropha JMP134  Bacteria  normal  0.898363  n/a   
 
 
-
 
NC_010831  Cphamn1_1488  C4-dicarboxylate transporter/malic acid transport protein  20.94 
 
 
326 aa  45.4  0.002  Chlorobium phaeobacteroides BS1  Bacteria  normal  0.138957  normal 
 
 
-
 
NC_010172  Mext_0212  C4-dicarboxylate transporter/malic acid transport protein  25.4 
 
 
335 aa  43.9  0.005  Methylobacterium extorquens PA1  Bacteria  normal  0.187317  normal 
 
 
-
 
NC_008740  Maqu_0374  C4-dicarboxylate transporter/malic acid transport protein  21.12 
 
 
321 aa  43.9  0.005  Marinobacter aquaeolei VT8  Bacteria  normal  0.273821  n/a   
 
 
-
 
NC_013512  Sdel_2052  C4-dicarboxylate transporter/malic acid transport protein  21.4 
 
 
322 aa  43.5  0.006  Sulfurospirillum deleyianum DSM 6946  Bacteria  normal  n/a   
 
 
-
 
NC_011757  Mchl_0156  C4-dicarboxylate transporter/malic acid transport protein  25.4 
 
 
335 aa  43.1  0.008  Methylobacterium chloromethanicum CM4  Bacteria  normal  0.131212  normal  0.103704 
 
 
-
 
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