91 homologs were found in PanDaTox collection
for query gene Mchl_0509 on replicon NC_011757
Organism: Methylobacterium chloromethanicum CM4



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_011757  Mchl_0509  putative anti-sigma regulatory factor, serine/threonine protein kinase  100 
 
 
333 aa  646    Methylobacterium chloromethanicum CM4  Bacteria  normal  normal 
 
 
-
 
NC_011757  Mchl_3342  putative anti-sigma regulatory factor, serine/threonine protein kinase  99.4 
 
 
333 aa  644    Methylobacterium chloromethanicum CM4  Bacteria  normal  0.50307  normal 
 
 
-
 
NC_010505  Mrad2831_5232  putative anti-sigma regulatory factor, serine/threonine protein kinase  79.22 
 
 
331 aa  494  1e-139  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  0.604718  normal 
 
 
-
 
NC_009712  Mboo_1495  stage II sporulation E family protein  41.67 
 
 
346 aa  258  7e-68  Candidatus Methanoregula boonei 6A8  Archaea  normal  0.520612  normal  0.134288 
 
 
-
 
NC_009675  Anae109_0802  putative anti-sigma regulatory factor, serine/threonine protein kinase  48.77 
 
 
335 aa  248  1e-64  Anaeromyxobacter sp. Fw109-5  Bacteria  normal  0.132982  normal  0.0114408 
 
 
-
 
NC_007952  Bxe_B2489  anti-sigma regulatory factor (Ser/Thr protein kinase and phosphatase)  43.69 
 
 
330 aa  246  4e-64  Burkholderia xenovorans LB400  Bacteria  normal  normal 
 
 
-
 
NC_010676  Bphyt_5776  putative anti-sigma regulatory factor, serine/threonine protein kinase  41.54 
 
 
330 aa  231  9e-60  Burkholderia phytofirmans PsJN  Bacteria  normal  normal 
 
 
-
 
NC_008009  Acid345_2413  anti-sigma regulatory factor, serine/threonine protein kinase and phosphatase  42.33 
 
 
342 aa  227  2e-58  Candidatus Koribacter versatilis Ellin345  Bacteria  normal  normal 
 
 
-
 
NC_013595  Sros_2266  putative anti-sigma regulatory factor, serine/threonine protein kinase  41.93 
 
 
337 aa  223  4e-57  Streptosporangium roseum DSM 43021  Bacteria  normal  normal  0.178715 
 
 
-
 
NC_007348  Reut_B4973  ATP-binding protein  41.69 
 
 
348 aa  222  8e-57  Ralstonia eutropha JMP134  Bacteria  normal  n/a   
 
 
-
 
NC_010622  Bphy_0132  putative anti-sigma regulatory factor, serine/threonine protein kinase  40.22 
 
 
382 aa  212  7e-54  Burkholderia phymatum STM815  Bacteria  normal  normal 
 
 
-
 
NC_013061  Phep_2115  Stage II sporulation E family protein  33.54 
 
 
335 aa  195  9e-49  Pedobacter heparinus DSM 2366  Bacteria  normal  normal  0.614697 
 
 
-
 
NC_008752  Aave_2973  anti-sigma regulatory factor, serine/threonine protein kinase and phosphatase  38.58 
 
 
358 aa  191  2e-47  Acidovorax citrulli AAC00-1  Bacteria  normal  normal  0.516432 
 
 
-
 
NC_013093  Amir_3741  putative anti-sigma regulatory factor, serine/threonine protein kinase  41.16 
 
 
339 aa  188  1e-46  Actinosynnema mirum DSM 43827  Bacteria  normal  n/a   
 
 
-
 
NC_007492  Pfl01_3136  anti-sigma-regulatory factor (Ser/Thr protein kinase and phosphatase)  34.76 
 
 
338 aa  187  3e-46  Pseudomonas fluorescens Pf0-1  Bacteria  normal  0.505866  normal  0.706395 
 
 
-
 
NC_009441  Fjoh_3134  putative anti-sigma regulatory factor, serine/threonine protein kinase  32.1 
 
 
337 aa  185  9e-46  Flavobacterium johnsoniae UW101  Bacteria  normal  0.602251  n/a   
 
 
-
 
NC_014165  Tbis_0477  putative anti-sigma regulatory factor, serine/threonine protein kinase  38.94 
 
 
330 aa  184  2.0000000000000003e-45  Thermobispora bispora DSM 43833  Bacteria  normal  normal 
 
 
-
 
NC_010002  Daci_4408  putative anti-sigma regulatory factor, serine/threonine protein kinase  39.17 
 
 
347 aa  176  3e-43  Delftia acidovorans SPH-1  Bacteria  normal  normal 
 
 
-
 
NC_008255  CHU_1216  anti-sigma regulatory factor (Ser/Thr protein kinase)  30.84 
 
 
336 aa  176  6e-43  Cytophaga hutchinsonii ATCC 33406  Bacteria  normal  0.470174  normal 
 
 
-
 
NC_013037  Dfer_1674  putative anti-sigma regulatory factor, serine/threonine protein kinase  32.31 
 
 
335 aa  171  2e-41  Dyadobacter fermentans DSM 18053  Bacteria  normal  normal  0.128227 
 
 
-
 
NC_013132  Cpin_3765  putative anti-sigma regulatory factor, serine/threonine protein kinase  34.3 
 
 
343 aa  168  1e-40  Chitinophaga pinensis DSM 2588  Bacteria  normal  0.933404  normal  0.0854229 
 
 
-
 
NC_013131  Caci_2796  putative anti-sigma regulatory factor, serine/threonine protein kinase  33.63 
 
 
360 aa  142  8e-33  Catenulispora acidiphila DSM 44928  Bacteria  normal  normal 
 
 
-
 
NC_013158  Huta_0198  putative anti-sigma regulatory factor, serine/threonine protein kinase  33.66 
 
 
356 aa  140  3e-32  Halorhabdus utahensis DSM 12940  Archaea  normal  0.0791059  n/a   
 
 
-
 
NC_013159  Svir_31990  anti-sigma regulatory factor (Ser/Thr protein kinase)  33.13 
 
 
335 aa  140  3.9999999999999997e-32  Saccharomonospora viridis DSM 43017  Bacteria  normal  0.447378  normal  0.128313 
 
 
-
 
NC_014210  Ndas_3856  putative anti-sigma regulatory factor, serine/threonine protein kinase  34.62 
 
 
349 aa  139  4.999999999999999e-32  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  0.964763  normal  0.561641 
 
 
-
 
NC_009972  Haur_4853  protein serine/threonine phosphatase  30.17 
 
 
193 aa  80.1  0.00000000000005  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  n/a   
 
 
-
 
NC_011831  Cagg_0737  putative anti-sigma regulatory factor, serine/threonine protein kinase  38.74 
 
 
133 aa  79.7  0.00000000000007  Chloroflexus aggregans DSM 9485  Bacteria  normal  normal 
 
 
-
 
NC_011831  Cagg_3252  putative anti-sigma regulatory factor, serine/threonine protein kinase  44.64 
 
 
139 aa  79  0.0000000000001  Chloroflexus aggregans DSM 9485  Bacteria  normal  normal 
 
 
-
 
NC_010511  M446_6563  protein serine/threonine phosphatase  35.14 
 
 
197 aa  79  0.0000000000001  Methylobacterium sp. 4-46  Bacteria  normal  0.710712  normal  0.0215921 
 
 
-
 
NC_009523  RoseRS_2297  putative anti-sigma regulatory factor, serine/threonine protein kinase  41.3 
 
 
143 aa  76.6  0.0000000000005  Roseiflexus sp. RS-1  Bacteria  normal  normal 
 
 
-
 
NC_008044  TM1040_0138  hypothetical protein  28.29 
 
 
214 aa  76.3  0.0000000000007  Ruegeria sp. TM1040  Bacteria  normal  0.0100709  normal 
 
 
-
 
NC_013385  Adeg_1812  putative anti-sigma regulatory factor, serine/threonine protein kinase  39.84 
 
 
151 aa  75.9  0.000000000001  Ammonifex degensii KC4  Bacteria  normal  n/a   
 
 
-
 
NC_009972  Haur_4854  putative anti-sigma regulatory factor, serine/threonine protein kinase  41.58 
 
 
142 aa  75.5  0.000000000001  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  n/a   
 
 
-
 
NC_008044  TM1040_0139  putative anti-sigma regulatory factor, serine/threonine protein kinase  39.52 
 
 
140 aa  75.5  0.000000000001  Ruegeria sp. TM1040  Bacteria  normal  0.0189997  normal 
 
 
-
 
NC_009767  Rcas_3169  protein serine/threonine phosphatase  31.02 
 
 
192 aa  72.8  0.000000000007  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.822146  normal 
 
 
-
 
NC_009767  Rcas_3168  putative anti-sigma regulatory factor, serine/threonine protein kinase  41.75 
 
 
144 aa  72.8  0.000000000008  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.482123  normal 
 
 
-
 
NC_009523  RoseRS_0162  putative anti-sigma regulatory factor, serine/threonine protein kinase  38.74 
 
 
133 aa  71.6  0.00000000002  Roseiflexus sp. RS-1  Bacteria  normal  normal 
 
 
-
 
NC_009767  Rcas_0675  putative anti-sigma regulatory factor, serine/threonine protein kinase  37.84 
 
 
133 aa  70.9  0.00000000003  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.769358  normal  0.0108346 
 
 
-
 
NC_011831  Cagg_3251  protein serine/threonine phosphatase  31.55 
 
 
192 aa  69.7  0.00000000006  Chloroflexus aggregans DSM 9485  Bacteria  normal  normal 
 
 
-
 
NC_007644  Moth_1473  putative anti-sigma regulatory factor (serine/threonine protein kinase)  35.59 
 
 
135 aa  70.1  0.00000000006  Moorella thermoacetica ATCC 39073  Bacteria  hitchhiker  0.00187817  normal 
 
 
-
 
NC_009441  Fjoh_3135  putative anti-sigma regulatory factor, serine/threonine protein kinase  30.33 
 
 
137 aa  69.3  0.00000000008  Flavobacterium johnsoniae UW101  Bacteria  normal  0.109754  n/a   
 
 
-
 
NC_009972  Haur_2684  putative anti-sigma regulatory factor, serine/threonine protein kinase  33.98 
 
 
137 aa  67.8  0.0000000002  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  n/a   
 
 
-
 
NC_013739  Cwoe_3439  putative anti-sigma regulatory factor, serine/threonine protein kinase  42.15 
 
 
136 aa  67.4  0.0000000003  Conexibacter woesei DSM 14684  Bacteria  normal  0.438455  normal 
 
 
-
 
NC_013061  Phep_2116  ATP-binding region ATPase domain protein  32.52 
 
 
137 aa  67  0.0000000004  Pedobacter heparinus DSM 2366  Bacteria  normal  normal  0.538209 
 
 
-
 
NC_009523  RoseRS_2296  stage II sporulation E family protein  29.41 
 
 
191 aa  66.6  0.0000000005  Roseiflexus sp. RS-1  Bacteria  normal  normal 
 
 
-
 
NC_010424  Daud_0696  stage II sporulation E family protein  32.49 
 
 
208 aa  65.5  0.000000001  Candidatus Desulforudis audaxviator MP104C  Bacteria  normal  n/a   
 
 
-
 
NC_008255  CHU_1217  anti-sigma regulatory factor; Ser/Thr protein kinase  31.97 
 
 
141 aa  64.3  0.000000003  Cytophaga hutchinsonii ATCC 33406  Bacteria  normal  normal 
 
 
-
 
NC_008009  Acid345_2414  putative anti-sigma regulatory factor, serine/threonine protein kinase  37.29 
 
 
134 aa  62.8  0.000000008  Candidatus Koribacter versatilis Ellin345  Bacteria  normal  normal 
 
 
-
 
NC_010676  Bphyt_5777  putative anti-sigma regulatory factor, serine/threonine protein kinase  35.4 
 
 
155 aa  61.2  0.00000002  Burkholderia phytofirmans PsJN  Bacteria  normal  normal 
 
 
-
 
NC_013132  Cpin_3766  putative anti-sigma regulatory factor, serine/threonine protein kinase  39.76 
 
 
136 aa  61.2  0.00000003  Chitinophaga pinensis DSM 2588  Bacteria  normal  normal  0.069662 
 
 
-
 
NC_013037  Dfer_1673  putative anti-sigma regulatory factor, serine/threonine protein kinase  33.9 
 
 
139 aa  60.5  0.00000004  Dyadobacter fermentans DSM 18053  Bacteria  normal  normal  0.11126 
 
 
-
 
NC_007952  Bxe_B2488  putative anti-sigma regulatory factor (Ser/Thr protein kinase)  34.75 
 
 
129 aa  60.1  0.00000005  Burkholderia xenovorans LB400  Bacteria  normal  normal 
 
 
-
 
NC_013131  Caci_2795  putative anti-sigma regulatory factor, serine/threonine protein kinase  38.18 
 
 
139 aa  59.3  0.00000008  Catenulispora acidiphila DSM 44928  Bacteria  normal  normal 
 
 
-
 
NC_014165  Tbis_0476  putative anti-sigma regulatory factor, serine/threonine protein kinase  33.93 
 
 
134 aa  58.2  0.0000002  Thermobispora bispora DSM 43833  Bacteria  normal  normal 
 
 
-
 
NC_013158  Huta_0197  putative anti-sigma regulatory factor, serine/threonine protein kinase  34.48 
 
 
144 aa  57.4  0.0000003  Halorhabdus utahensis DSM 12940  Archaea  normal  0.0569328  n/a   
 
 
-
 
NC_013522  Taci_0691  putative anti-sigma regulatory factor, serine/threonine protein kinase  34.26 
 
 
142 aa  57  0.0000005  Thermanaerovibrio acidaminovorans DSM 6589  Bacteria  normal  n/a   
 
 
-
 
NC_013739  Cwoe_3440  protein serine/threonine phosphatase  35.53 
 
 
222 aa  56.6  0.0000006  Conexibacter woesei DSM 14684  Bacteria  normal  normal 
 
 
-
 
NC_013093  Amir_3742  putative anti-sigma regulatory factor, serine/threonine protein kinase  36.63 
 
 
137 aa  55.8  0.0000009  Actinosynnema mirum DSM 43827  Bacteria  normal  0.943736  n/a   
 
 
-
 
NC_010622  Bphy_0131  putative anti-sigma regulatory factor, serine/threonine protein kinase  36.11 
 
 
141 aa  55.5  0.000001  Burkholderia phymatum STM815  Bacteria  normal  normal 
 
 
-
 
NC_009675  Anae109_0801  putative anti-sigma regulatory factor, serine/threonine protein kinase  35.19 
 
 
134 aa  54.7  0.000002  Anaeromyxobacter sp. Fw109-5  Bacteria  normal  0.0765191  normal  0.0123921 
 
 
-
 
NC_010505  Mrad2831_5233  histidine kinase  30.77 
 
 
638 aa  53.5  0.000005  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  normal 
 
 
-
 
NC_010511  M446_6564  putative anti-sigma regulatory factor, serine/threonine protein kinase  43.59 
 
 
137 aa  53.5  0.000005  Methylobacterium sp. 4-46  Bacteria  normal  normal  0.019429 
 
 
-
 
NC_008009  Acid345_2412  histidine kinase  35.96 
 
 
603 aa  53.1  0.000006  Candidatus Koribacter versatilis Ellin345  Bacteria  normal  normal 
 
 
-
 
NC_013159  Svir_32000  anti-sigma regulatory factor (Ser/Thr protein kinase)  34.15 
 
 
134 aa  52.8  0.000007  Saccharomonospora viridis DSM 43017  Bacteria  normal  0.124407  normal  0.112833 
 
 
-
 
NC_007348  Reut_B4972  ATP-binding region, ATPase-like  32.65 
 
 
152 aa  52.4  0.00001  Ralstonia eutropha JMP134  Bacteria  normal  n/a   
 
 
-
 
NC_007644  Moth_1472  serine phosphatase  29.69 
 
 
193 aa  52.4  0.00001  Moorella thermoacetica ATCC 39073  Bacteria  normal  0.143457  normal 
 
 
-
 
NC_012034  Athe_1291  putative anti-sigma regulatory factor, serine/threonine protein kinase  31.36 
 
 
139 aa  50.8  0.00003  Anaerocellum thermophilum DSM 6725  Bacteria  normal  n/a   
 
 
-
 
NC_014210  Ndas_3857  putative anti-sigma regulatory factor, serine/threonine protein kinase  35.19 
 
 
144 aa  50.1  0.00005  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  normal  0.479572 
 
 
-
 
NC_009616  Tmel_0628  signal transduction protein  33.96 
 
 
307 aa  49.7  0.00007  Thermosipho melanesiensis BI429  Bacteria  normal  n/a   
 
 
-
 
NC_009712  Mboo_1494  putative anti-sigma regulatory factor, serine/threonine protein kinase  34.82 
 
 
134 aa  49.3  0.00009  Candidatus Methanoregula boonei 6A8  Archaea  normal  0.222585  normal  0.076378 
 
 
-
 
NC_010511  M446_6565  putative anti-sigma regulatory factor, serine/threonine protein kinase  43.43 
 
 
155 aa  48.1  0.0002  Methylobacterium sp. 4-46  Bacteria  normal  0.849922  normal  0.0440893 
 
 
-
 
NC_009718  Fnod_0657  signal transduction protein  32.5 
 
 
309 aa  48.5  0.0002  Fervidobacterium nodosum Rt17-B1  Bacteria  hitchhiker  0.00784458  n/a   
 
 
-
 
NC_009675  Anae109_0803  histidine kinase  30.4 
 
 
718 aa  47.8  0.0003  Anaeromyxobacter sp. Fw109-5  Bacteria  normal  0.0571523  hitchhiker  0.00843936 
 
 
-
 
NC_007492  Pfl01_3135  putative anti-sigma-regulatory factor (Ser/Thr protein kinase)  30.7 
 
 
134 aa  47  0.0004  Pseudomonas fluorescens Pf0-1  Bacteria  normal  normal  0.667596 
 
 
-
 
NC_010676  Bphyt_5775  histidine kinase  28.57 
 
 
554 aa  47  0.0005  Burkholderia phytofirmans PsJN  Bacteria  normal  normal  0.941039 
 
 
-
 
NC_011757  Mchl_3341  putative anti-sigma regulatory factor, serine/threonine protein kinase  39.29 
 
 
134 aa  46.6  0.0007  Methylobacterium chloromethanicum CM4  Bacteria  normal  0.480344  normal 
 
 
-
 
NC_011757  Mchl_0510  putative anti-sigma regulatory factor, serine/threonine protein kinase  39.29 
 
 
134 aa  46.6  0.0007  Methylobacterium chloromethanicum CM4  Bacteria  normal  normal 
 
 
-
 
NC_011661  Dtur_0911  putative anti-sigma regulatory factor, serine/threonine protein kinase  31.9 
 
 
290 aa  46.2  0.0007  Dictyoglomus turgidum DSM 6724  Bacteria  normal  n/a   
 
 
-
 
NC_011757  Mchl_0508  histidine kinase  27.12 
 
 
632 aa  45.4  0.001  Methylobacterium chloromethanicum CM4  Bacteria  normal  normal 
 
 
-
 
NC_011757  Mchl_3343  histidine kinase  27.12 
 
 
632 aa  45.1  0.002  Methylobacterium chloromethanicum CM4  Bacteria  normal  normal 
 
 
-
 
NC_009486  Tpet_1429  putative anti-sigma regulatory factor, serine/threonine protein kinase  33.96 
 
 
321 aa  44.7  0.002  Thermotoga petrophila RKU-1  Bacteria  normal  n/a   
 
 
-
 
NC_010483  TRQ2_1475  putative anti-sigma regulatory factor, serine/threonine protein kinase  33.96 
 
 
321 aa  44.7  0.002  Thermotoga sp. RQ2  Bacteria  normal  n/a   
 
 
-
 
NC_013216  Dtox_0179  putative anti-sigma regulatory factor, serine/threonine protein kinase  28.81 
 
 
142 aa  44.3  0.003  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  normal 
 
 
-
 
NC_007952  Bxe_B2490  histidine kinase  30.77 
 
 
554 aa  43.9  0.004  Burkholderia xenovorans LB400  Bacteria  normal  normal 
 
 
-
 
NC_013385  Adeg_1813  protein serine/threonine phosphatase  23.31 
 
 
203 aa  43.9  0.004  Ammonifex degensii KC4  Bacteria  normal  n/a   
 
 
-
 
NC_013595  Sros_2267  putative anti-sigma regulatory factor, serine/threonine protein kinase  32.79 
 
 
133 aa  43.9  0.004  Streptosporangium roseum DSM 43021  Bacteria  normal  normal  0.144114 
 
 
-
 
NC_009712  Mboo_1496  signal transduction histidine kinase  25.62 
 
 
1253 aa  43.1  0.006  Candidatus Methanoregula boonei 6A8  Archaea  normal  normal  0.172842 
 
 
-
 
NC_010505  Mrad2831_5231  putative anti-sigma regulatory factor, serine/threonine protein kinase  34.83 
 
 
134 aa  42.7  0.009  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  0.388925  normal 
 
 
-
 
NC_007494  RSP_3217  Cache sensor signal transduction histidine kinase  29.36 
 
 
699 aa  42.7  0.009  Rhodobacter sphaeroides 2.4.1  Bacteria  normal  n/a   
 
 
-
 
NC_013595  Sros_7255  Signal transduction histidine kinase-like protein  37.97 
 
 
446 aa  42.7  0.009  Streptosporangium roseum DSM 43021  Bacteria  normal  normal  0.151364 
 
 
-
 
NC_009050  Rsph17029_3958  multi-sensor signal transduction histidine kinase  29.36 
 
 
699 aa  42.7  0.009  Rhodobacter sphaeroides ATCC 17029  Bacteria  normal  0.508028  normal 
 
 
-
 
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