160 decreased-coverage genes were found for selected organism/s



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Locus tag

Gene type

Replicon accession

From

To

Strand

Gene Length

Product

Protein accession

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Organism name

Kingdom

Coverage Plot

PanDaTox homologs

Experimental validation
TBFG_10018  CDS  NC_009565  21738  23282  1545  serine/threonine phosphatase ppp  YP_001285963  decreased coverage  0.000837689  normal  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_10058  CDS  NC_009565  63304  63996  693  hypothetical protein  YP_001286003  decreased coverage  2.41088e-98  normal  0.757515  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_10071  CDS  NC_009565  79628  80326  699  maturase  YP_001286016  decreased coverage  0.000865432  normal  0.0655357  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_10086  CDS  NC_009565  93422  94084  663  hydrogenase hycP  YP_001286031  decreased coverage  9.6186e-11  normal  0.18173  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_10125  CDS  NC_009565  149627  151312  1686  PE-PGRS family protein  YP_001286070  decreased coverage  1.1228e-10  normal  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_10161  CDS  NC_009565  189247  190755  1509  PE family protein  YP_001286106  decreased coverage  0.00736493  normal  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_10208  CDS  NC_009565  244802  247636  2835  transmembrane transport protein mmpL3  YP_001286153  decreased coverage  0.0021573  normal  0.454475  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_10285  CDS  NC_009565  336752  339472  2721  PE-PGRS family protein  YP_001286230  decreased coverage  1.92954e-51  normal  0.572415  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_10297  CDS  NC_009565  356224  357642  1419  transmembrane protein  YP_001286242  decreased coverage  8.83477e-06  normal  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_10298  CDS  NC_009565  357639  359024  1386  membrane-anchored mycosin mycP3  YP_001286243  decreased coverage  0.000199047  normal  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_10385  CDS  NC_009565  459436  460098  663  RNA methyltransferase  YP_001286330  decreased coverage  1.85641e-18  normal  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_10392  CDS  NC_009565  469840  471171  1332  PPE family protein  YP_001286337  decreased coverage  1.54935e-05  normal  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_10415  CDS  NC_009565  498232  500484  2253  serine/threonine-protein kinase pknG  YP_001286360  decreased coverage  1.00112e-05  normal  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_10445  CDS  NC_009565  531778  533400  1623  chaperonin GroEL  YP_001286390  decreased coverage  0.00698847  normal  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_10499  CDS  NC_009565  583954  584637  684  two component system sensor transduction protein regX3  YP_001286444  decreased coverage  2.46064e-66  normal  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_10543  CDS  NC_009565  625937  627805  1869  PE-PGRS family protein  YP_001286488  decreased coverage  2.97134e-40  normal  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_10588  CDS  NC_009565  675224  679144  3921  PE-PGRS family protein  YP_001286533  decreased coverage  0.00297042  normal  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_10615  CDS  NC_009565  703467  704417  951  lipoprotein lpqO  YP_001286560  decreased coverage  3.27081e-10  normal  0.345127  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_10640  CDS  NC_009565  723233  724960  1728  exonuclease V alpha subunit recD  YP_001286585  decreased coverage  1.47997e-19  normal  0.376997  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_10661  CDS  NC_009565  745931  750127  4197  alpha-mannosidase  YP_001286606  decreased coverage  2.36587e-06  normal  0.132856  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_10663  CDS  NC_009565  750798  751706  909  sugar kinase  YP_001286608  decreased coverage  6.97302e-41  normal  0.432322  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_10683  CDS  NC_009565  771445  773358  1914  hydrolase  YP_001286628  decreased coverage  0.000458391  normal  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_10736  CDS  NC_009565  818862  819059  198  50S ribosomal protein L30  YP_001286681  decreased coverage  1.07725e-06  normal  0.417501  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_10761  CDS  NC_009565  842320  844725  2406  PE-PGRS family protein  YP_001286706  decreased coverage  1.20056e-53  normal  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_10808  CDS  NC_009565  889707  890516  810  GntR family transcriptional regulator  YP_001286753  decreased coverage  2.18529e-05  normal  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_10841  CDS  NC_009565  922145  923200  1056  hypothetical protein  YP_001286786  decreased coverage  8.27324e-31  hitchhiker  1.89365e-06  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_10848  CDS  NC_009565  927872  930076  2205  PE-PGRS family protein  YP_001286793  decreased coverage  1.93825e-51  hitchhiker  1.06302e-06  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_10852  CDS  NC_009565  934704  935588  885  transposase  YP_001286797  hitchhiker  5.90169e-44  decreased coverage  1.61998e-08  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_10854  CDS  NC_009565  936094  936840  747  hypothetical protein  YP_001286799  hitchhiker  6.52115e-35  decreased coverage  7.84145e-09  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_10885  CDS  NC_009565  969798  970076  279  molybdenum cofactor biosynthesis protein D 2 moaD2  YP_001286830  decreased coverage  3.91513e-26  normal  0.142298  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_10981  CDS  NC_009565  1079120  1080082  963  hypothetical protein  YP_001286926  decreased coverage  1.23037e-10  normal  0.880306  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_10988  CDS  NC_009565  1084875  1085507  633  integral membrane protein  YP_001286933  decreased coverage  6.82985e-07  normal  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_10995  CDS  NC_009565  1094196  1096967  2772  PE-PGRS family protein  YP_001286940  decreased coverage  5.02084e-24  normal  0.770391  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_11005  CDS  NC_009565  1106310  1108877  2568  adhesion ABC transporter transmembrane protein  YP_001286950  decreased coverage  6.05567e-37  normal  0.438455  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_11014  CDS  NC_009565  1116053  1117228  1176  transmembrane protein  YP_001286959  decreased coverage  0.00967032  normal  0.807304  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_11023  CDS  NC_009565  1124657  1125955  1299  hypothetical protein  YP_001286968  decreased coverage  9.91608e-06  normal  0.293529  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_11085  CDS  NC_009565  1192191  1194194  2004  PE-PGRS family protein  YP_001287030  decreased coverage  3.21525e-28  normal  0.25323  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_11105  CDS  NC_009565  1215291  1217630  2340  PE-PGRS family protein  YP_001287050  decreased coverage  5.19894e-57  normal  0.745031  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_11183  CDS  NC_009565  1288756  1290051  1296  mannosyltransferase  YP_001287128  decreased coverage  6.55823e-08  normal  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_11214  CDS  NC_009565  1336745  1337623  879  hypothetical protein  YP_001287159  decreased coverage  0.00241452  normal  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_11223  CDS  NC_009565  1345122  1346369  1248  transposase  YP_001287168  decreased coverage  1.46016e-12  normal  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_11265  CDS  NC_009565  1386979  1387968  990  malate dehydrogenase  YP_001287210  hitchhiker  4.944e-14  decreased coverage  0.000678049  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_11268  CDS  NC_009565  1388755  1389309  555  PE-PGRS family protein  YP_001287213  decreased coverage  1.13553e-20  hitchhiker  0.000894273  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_11292  CDS  NC_009565  1417727  1419607  1881  transmembrane serine/threonine-protein kinase H pknH  YP_001287237  decreased coverage  3.74937e-08  normal  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_11347  CDS  NC_009565  1485350  1485676  327  transposase  YP_001287292  decreased coverage  3.37726e-34  normal  0.888349  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_11348  CDS  NC_009565  1485775  1486611  837  transposase  YP_001287293  decreased coverage  4.0645e-27  normal  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_11349  CDS  NC_009565  1486616  1487617  1002  adenylate cyclase  YP_001287294  decreased coverage  1.3765e-27  normal  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_11366  CDS  NC_009565  1509494  1510063  570  cysteine synthase B cysM  YP_001287311  decreased coverage  9.90079e-22  normal  0.290845  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_11416  CDS  NC_009565  1566110  1567729  1620  PPE family protein  YP_001287361  decreased coverage  7.93928e-11  normal  0.128386  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_11425  CDS  NC_009565  1576468  1578198  1731  PE-PGRS family protein  YP_001287370  decreased coverage  1.00458e-10  normal  0.0951709  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_11438  CDS  NC_009565  1589535  1590554  1020  bifunctional riboflavin biosynthesis protein ribG: diaminohydroxyphosphoribosylaminopyrimidine deaminase + 5-amino-6-(5-phosphoribosylamino) uracil reductase  YP_001287383  decreased coverage  0.00260487  normal  0.1412  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_11466  CDS  NC_009565  1619926  1620711  786  triosephosphate isomerase  YP_001287411  decreased coverage  2.35283e-12  normal  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_11478  CDS  NC_009565  1635000  1639223  4224  PE-PGRS family protein  YP_001287423  decreased coverage  2.17058e-15  normal  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_11489  CDS  NC_009565  1651626  1654166  2541  hypothetical protein  YP_001287434  decreased coverage  0.000249036  normal  0.700584  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_11496  CDS  NC_009565  1660246  1661373  1128  PE-PGRS family protein  YP_001287441  decreased coverage  6.34061e-07  normal  0.0755488  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_11590  CDS  NC_009565  1767585  1768031  447  hypothetical protein  YP_001287535  decreased coverage  1.30585e-85  normal  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_11604  CDS  NC_009565  1783832  1784554  723  REP13E12 repeat-containing protein  YP_001287549  decreased coverage  1.81222e-18  normal  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_11669  CDS  NC_009565  1859123  1860772  1650  PE-PGRS family protein  YP_001287614  decreased coverage  8.43838e-17  normal  0.300456  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_11675  CDS  NC_009565  1866214  1866744  531  arginine repressor  YP_001287620  decreased coverage  1.20822e-16  normal  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_11679  CDS  NC_009565  1870694  1877074  6381  polyketide synthase pks7  YP_001287624  decreased coverage  0.00819043  normal  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_11729  CDS  NC_009565  1937082  1937894  813  oxidoreductase  YP_001287674  decreased coverage  1.23352e-12  normal  0.515207  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_11738  misc_feature  NC_009565  1945860  1947634  1775      decreased coverage  6.28559e-27  normal  0.52056  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_11739  CDS  NC_009565  1946034  1946918  885  transposase  YP_001287683  decreased coverage  3.46568e-46  normal  0.519629  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_11771  CDS  NC_009565  1978314  1981241  2928  PPE family protein  YP_001287714  decreased coverage  1.49393e-28  hitchhiker  1.53091e-08  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_11778  CDS  NC_009565  1989026  1991863  2838  MmpL family membrane protein  YP_001287721  hitchhiker  7.86949e-15  decreased coverage  1.13435e-11  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_11779  misc_feature  NC_009565  1992034  1994198  2165      decreased coverage  5.29759e-44  hitchhiker  2.59187e-09  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_11780  CDS  NC_009565  1992399  1993283  885  transposase  YP_001287722  decreased coverage  8.89938e-72  hitchhiker  1.93173e-09  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_11785  CDS  NC_009565  1997791  1998675  885  transposase  YP_001287726  decreased coverage  6.8775e-79  hitchhiker  1.84324e-08  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_11791  CDS  NC_009565  2004236  2004562  327  transposase  YP_001287732  decreased coverage  7.32462e-61  hitchhiker  3.85538e-06  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_11798  CDS  NC_009565  2010818  2012104  1287  hypothetical protein  YP_001287739  decreased coverage  2.48048e-06  hitchhiker  0.000230946  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_11805  misc_feature  NC_009565  2017596  2020258  2663      decreased coverage  8.2739e-08  normal  0.0295983  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_11806  CDS  NC_009565  2017907  2018791  885  transposase  YP_001287746  decreased coverage  2.55346e-33  hitchhiker  0.00499729  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_11834  CDS  NC_009565  2053175  2055127  1953  PE-PGRS family protein  YP_001287771  decreased coverage  0.00239965  normal  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_11868  CDS  NC_009565  2096167  2097714  1548  PE-PGRS family protein  YP_001287805  decreased coverage  4.73061e-05  normal  0.517398  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_11999  CDS  NC_009565  2219880  2221112  1233  MCE-family protein mce3C  YP_001287936  decreased coverage  1.02981e-07  normal  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_12007  CDS  NC_009565  2227098  2227505  408  hypothetical protein  YP_001287944  decreased coverage  9.40488e-13  normal  0.526902  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_12048  CDS  NC_009565  2270484  2271368  885  transposase  YP_001287984  decreased coverage  1.2114e-18  normal  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_12049  CDS  NC_009565  2271419  2271745  327  transposase  YP_001287985  decreased coverage  1.40799e-27  normal  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_12088  CDS  NC_009565  2322743  2325367  2625  polyprenol-monophosphomannose synthase ppm1  YP_001288021  decreased coverage  0.000628532  normal  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_12098  CDS  NC_009565  2331781  2335365  3585  cobaltochelatase subunit CobN  YP_001288031  decreased coverage  0.000146421  normal  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_12114  CDS  NC_009565  2349717  2350601  885  hypothetical protein  YP_001288047  decreased coverage  6.76426e-46  normal  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_12133  CDS  NC_009565  2372768  2373937  1170  PE-PGRS family protein  YP_001288066  decreased coverage  9.78875e-15  normal  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_12140  CDS  NC_009565  2381194  2381835  642  PPE family protein  YP_001288073  decreased coverage  6.95332e-49  normal  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_12189  CDS  NC_009565  2434192  2435226  1035  hypothetical protein  YP_001288122  decreased coverage  6.25676e-41  normal  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_12230  CDS  NC_009565  2479199  2480173  975  carbohydrate kinase cbhK  YP_001288163  decreased coverage  5.30804e-07  normal  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_12237  CDS  NC_009565  2485546  2487084  1539  integral membrane protein  YP_001288170  decreased coverage  0.000931894  normal  0.428946  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_12256  CDS  NC_009565  2513077  2513778  702  hypothetical protein  YP_001288189  decreased coverage  2.90448e-05  normal  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_12270  CDS  NC_009565  2524685  2527390  2706  pyruvate dehydrogenase subunit E1  YP_001288203  decreased coverage  2.671e-08  normal  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_12376  CDS  NC_009565  2643720  2644895  1176  PPE family protein  YP_001288307  decreased coverage  5.84927e-25  normal  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_12381  CDS  NC_009565  2649273  2650157  885  transposase  YP_001288312  decreased coverage  1.55066e-37  normal  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_12415  misc_feature  NC_009565  2697004  2698919  1916      decreased coverage  1.85069e-11  normal  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_12416  CDS  NC_009565  2697370  2698254  885  transposase  YP_001288346  decreased coverage  1.46754e-28  normal  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_12471  CDS  NC_009565  2756797  2759658  2862  ribonuclease E rne  YP_001288400  decreased coverage  0.00011708  normal  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_12501  CDS  NC_009565  2797040  2798716  1677  putative ABC transporter ATP-binding protein  YP_001288430  decreased coverage  0.0036999  normal  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_12508  CDS  NC_009565  2808617  2809378  762  PE-PGRS family protein  YP_001288437  decreased coverage  2.47801e-44  normal  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_12512  CDS  NC_009565  2814571  2818809  4239  PE-PGRS family protein  YP_001288441  decreased coverage  2.36671e-11  normal  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_12534  CDS  NC_009565  2841874  2843121  1248  transposase  YP_001288463  normal  0.922715  decreased coverage  0.00121453  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_12545  CDS  NC_009565  2853441  2862650  9210  fatty acid synthase fas  YP_001288474  normal  0.696473  decreased coverage  0.00343939  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_12561  CDS  NC_009565  2877745  2878152  408  hypothetical protein  YP_001288490  decreased coverage  4.41895e-13  normal  0.127822  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
TBFG_12572  CDS  NC_009565  2884093  2884512  420  hypothetical protein  YP_001288501  decreased coverage  0.000763367  normal  0.175513  Mycobacterium tuberculosis F11  Bacteria 
 
 
-
 
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