More than 300 homologs were found in PanDaTox collection
for query gene M446_5359 on replicon NC_010511
Organism: Methylobacterium sp. 4-46



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_010511  M446_5359  response regulator receiver modulated metal dependent phosphohydrolase  100 
 
 
347 aa  683    Methylobacterium sp. 4-46  Bacteria  normal  normal  0.0670454 
 
 
-
 
NC_011757  Mchl_0538  response regulator receiver modulated metal dependent phosphohydrolase  72.02 
 
 
363 aa  475  1e-133  Methylobacterium chloromethanicum CM4  Bacteria  normal  0.973232  normal 
 
 
-
 
NC_010725  Mpop_3894  response regulator receiver modulated metal dependent phosphohydrolase  71.14 
 
 
353 aa  477  1e-133  Methylobacterium populi BJ001  Bacteria  normal  0.0109719  normal  0.416002 
 
 
-
 
NC_010172  Mext_3509  metal-dependent phosphohydrolase  70.8 
 
 
351 aa  471  1e-132  Methylobacterium extorquens PA1  Bacteria  normal  0.305053  normal 
 
 
-
 
NC_011757  Mchl_3816  response regulator receiver modulated metal dependent phosphohydrolase  70.8 
 
 
351 aa  472  1e-132  Methylobacterium chloromethanicum CM4  Bacteria  normal  0.0960158  normal 
 
 
-
 
NC_010505  Mrad2831_2085  response regulator receiver modulated metal dependent phosphohydrolase  70.06 
 
 
345 aa  467  9.999999999999999e-131  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  0.931733  normal  0.012958 
 
 
-
 
NC_012850  Rleg_3169  response regulator receiver modulated metal dependent phosphohydrolase  49.13 
 
 
353 aa  308  5.9999999999999995e-83  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  0.821118  normal 
 
 
-
 
NC_010172  Mext_0206  metal-dependent phosphohydrolase  48.71 
 
 
369 aa  305  6e-82  Methylobacterium extorquens PA1  Bacteria  normal  0.44114  normal  0.760724 
 
 
-
 
NC_011757  Mchl_0150  response regulator receiver modulated metal dependent phosphohydrolase  48.71 
 
 
369 aa  305  6e-82  Methylobacterium chloromethanicum CM4  Bacteria  normal  normal  0.245203 
 
 
-
 
NC_011901  Tgr7_0081  two component transcriptional regulator, AraC family  49.24 
 
 
399 aa  301  1e-80  Thioalkalivibrio sp. HL-EbGR7  Bacteria  normal  n/a   
 
 
-
 
NC_011004  Rpal_0148  response regulator receiver modulated metal dependent phosphohydrolase  50.97 
 
 
385 aa  300  3e-80  Rhodopseudomonas palustris TIE-1  Bacteria  normal  0.750781  n/a   
 
 
-
 
NC_010505  Mrad2831_1613  response regulator receiver modulated metal dependent phosphohydrolase  49.4 
 
 
487 aa  293  2e-78  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  0.350204  hitchhiker  0.000130728 
 
 
-
 
NC_010511  M446_0838  response regulator receiver modulated metal dependent phosphohydrolase  48.08 
 
 
378 aa  293  2e-78  Methylobacterium sp. 4-46  Bacteria  normal  0.8404  normal 
 
 
-
 
NC_007298  Daro_2902  response regulator receiver  45.65 
 
 
350 aa  293  3e-78  Dechloromonas aromatica RCB  Bacteria  normal  0.1984  normal  0.246098 
 
 
-
 
NC_011662  Tmz1t_1183  response regulator receiver modulated metal dependent phosphohydrolase  48.38 
 
 
363 aa  293  4e-78  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_010725  Mpop_4963  response regulator receiver modulated metal dependent phosphohydrolase  54.48 
 
 
350 aa  292  5e-78  Methylobacterium populi BJ001  Bacteria  normal  0.102256  normal  0.0892849 
 
 
-
 
NC_011989  Avi_4319  Metal dependent phosphohydrolase with a response regulator receiver protein  48.21 
 
 
382 aa  292  6e-78  Agrobacterium vitis S4  Bacteria  normal  n/a   
 
 
-
 
NC_011989  Avi_0523  Response regulator protein  44.38 
 
 
359 aa  290  3e-77  Agrobacterium vitis S4  Bacteria  normal  n/a   
 
 
-
 
NC_011894  Mnod_5340  response regulator receiver modulated metal dependent phosphohydrolase  55.52 
 
 
348 aa  283  3.0000000000000004e-75  Methylobacterium nodulans ORS 2060  Bacteria  normal  0.64097  n/a   
 
 
-
 
NC_010511  M446_5034  response regulator receiver modulated metal dependent phosphohydrolase  54.96 
 
 
348 aa  275  7e-73  Methylobacterium sp. 4-46  Bacteria  normal  0.749308  hitchhiker  0.00297277 
 
 
-
 
NC_007947  Mfla_2655  response regulator receiver (CheY-like) modulated metal dependent phosphohydrolase  42.73 
 
 
353 aa  274  1.0000000000000001e-72  Methylobacillus flagellatus KT  Bacteria  normal  normal 
 
 
-
 
NC_010172  Mext_4449  metal-dependent phosphohydrolase  51.59 
 
 
358 aa  273  2.0000000000000002e-72  Methylobacterium extorquens PA1  Bacteria  normal  normal  0.508967 
 
 
-
 
NC_011757  Mchl_4913  response regulator receiver modulated metal dependent phosphohydrolase  54.55 
 
 
354 aa  273  3e-72  Methylobacterium chloromethanicum CM4  Bacteria  normal  0.478904  normal  0.760596 
 
 
-
 
NC_007404  Tbd_2670  metal dependent phosphohydrolase, HD region  48.87 
 
 
344 aa  272  5.000000000000001e-72  Thiobacillus denitrificans ATCC 25259  Bacteria  normal  normal 
 
 
-
 
NC_011071  Smal_1828  response regulator receiver modulated metal dependent phosphohydrolase  47.12 
 
 
379 aa  266  4e-70  Stenotrophomonas maltophilia R551-3  Bacteria  normal  normal  0.723665 
 
 
-
 
NC_010717  PXO_00070  Two-component system response regulator RpfG  45.83 
 
 
353 aa  258  9e-68  Xanthomonas oryzae pv. oryzae PXO99A  Bacteria  normal  0.0844737  n/a   
 
 
-
 
NC_010577  XfasM23_0399  response regulator receiver modulated metal dependent phosphohydrolase  44.55 
 
 
384 aa  253  4.0000000000000004e-66  Xylella fastidiosa M23  Bacteria  normal  n/a   
 
 
-
 
NC_010513  Xfasm12_0458  response regulator receiver protein  44.55 
 
 
384 aa  253  4.0000000000000004e-66  Xylella fastidiosa M12  Bacteria  normal  n/a   
 
 
-
 
NC_010172  Mext_0459  response regulator receiver  71.1 
 
 
176 aa  240  2e-62  Methylobacterium extorquens PA1  Bacteria  normal  normal  0.493555 
 
 
-
 
NC_008576  Mmc1_3408  response regulator receiver modulated metal dependent phosphohydrolase  43.2 
 
 
346 aa  239  4e-62  Magnetococcus sp. MC-1  Bacteria  normal  normal 
 
 
-
 
NC_008576  Mmc1_3165  response regulator receiver modulated metal dependent phosphohydrolase  41.72 
 
 
367 aa  237  2e-61  Magnetococcus sp. MC-1  Bacteria  normal  0.0569095  normal  0.0154692 
 
 
-
 
NC_013216  Dtox_4196  response regulator receiver modulated metal dependent phosphohydrolase  42.76 
 
 
350 aa  237  2e-61  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  normal 
 
 
-
 
NC_010506  Swoo_3823  response regulator receiver modulated metal dependent phosphohydrolase  34.41 
 
 
354 aa  231  2e-59  Shewanella woodyi ATCC 51908  Bacteria  normal  normal 
 
 
-
 
NC_010002  Daci_6015  response regulator receiver modulated metal dependent phosphohydrolase  43.62 
 
 
333 aa  231  2e-59  Delftia acidovorans SPH-1  Bacteria  normal  normal 
 
 
-
 
NC_009831  Ssed_3915  response regulator receiver modulated metal dependent phosphohydrolase  33.53 
 
 
356 aa  231  2e-59  Shewanella sediminis HAW-EB3  Bacteria  normal  normal 
 
 
-
 
NC_010814  Glov_3523  response regulator receiver modulated metal dependent phosphohydrolase  41.37 
 
 
363 aa  230  3e-59  Geobacter lovleyi SZ  Bacteria  normal  n/a   
 
 
-
 
NC_007298  Daro_0007  response regulator receiver modulated metal dependent phosphohydrolase  39.94 
 
 
379 aa  229  4e-59  Dechloromonas aromatica RCB  Bacteria  normal  0.829613  normal  0.0284762 
 
 
-
 
NC_009997  Sbal195_0871  response regulator receiver modulated metal dependent phosphohydrolase  42.12 
 
 
338 aa  228  1e-58  Shewanella baltica OS195  Bacteria  normal  normal 
 
 
-
 
NC_009052  Sbal_3504  response regulator receiver modulated metal dependent phosphohydrolase  42.12 
 
 
338 aa  227  2e-58  Shewanella baltica OS155  Bacteria  normal  n/a   
 
 
-
 
NC_011663  Sbal223_0859  response regulator receiver modulated metal dependent phosphohydrolase  42.12 
 
 
338 aa  227  2e-58  Shewanella baltica OS223  Bacteria  normal  normal 
 
 
-
 
NC_009092  Shew_3199  response regulator receiver modulated metal dependent phosphohydrolase  44.29 
 
 
339 aa  228  2e-58  Shewanella loihica PV-4  Bacteria  normal  normal 
 
 
-
 
NC_009665  Shew185_0836  response regulator receiver modulated metal dependent phosphohydrolase  42.12 
 
 
338 aa  227  2e-58  Shewanella baltica OS185  Bacteria  normal  n/a   
 
 
-
 
NC_009438  Sputcn32_3141  response regulator receiver modulated metal dependent phosphohydrolase  41.38 
 
 
338 aa  226  3e-58  Shewanella putrefaciens CN-32  Bacteria  normal  n/a   
 
 
-
 
NC_012560  Avin_50640  response regulator with metal dependent phosphohydrolase activity (two-component)  42.42 
 
 
347 aa  226  4e-58  Azotobacter vinelandii DJ  Bacteria  normal  0.121542  n/a   
 
 
-
 
NC_004347  SO_0860  response regulator  41.38 
 
 
339 aa  226  4e-58  Shewanella oneidensis MR-1  Bacteria  n/a    n/a   
 
 
-
 
NC_008321  Shewmr4_0716  response regulator receiver modulated metal dependent phosphohydrolase  41.03 
 
 
338 aa  226  4e-58  Shewanella sp. MR-4  Bacteria  normal  normal 
 
 
-
 
NC_008322  Shewmr7_3306  response regulator receiver modulated metal dependent phosphohydrolase  41.03 
 
 
338 aa  226  4e-58  Shewanella sp. MR-7  Bacteria  normal  normal 
 
 
-
 
NC_008577  Shewana3_3418  response regulator receiver modulated metal dependent phosphohydrolase  41.03 
 
 
338 aa  226  4e-58  Shewanella sp. ANA-3  Bacteria  normal  normal 
 
 
-
 
NC_010506  Swoo_3313  response regulator receiver modulated metal dependent phosphohydrolase  40.12 
 
 
343 aa  225  7e-58  Shewanella woodyi ATCC 51908  Bacteria  normal  hitchhiker  0.00000482447 
 
 
-
 
NC_009901  Spea_0629  response regulator receiver modulated metal dependent phosphohydrolase  39.88 
 
 
339 aa  225  7e-58  Shewanella pealeana ATCC 700345  Bacteria  normal  n/a   
 
 
-
 
NC_009654  Mmwyl1_1086  response regulator receiver modulated metal dependent phosphohydrolase  40.48 
 
 
331 aa  225  1e-57  Marinomonas sp. MWYL1  Bacteria  normal  0.226857  hitchhiker  0.0000000112469 
 
 
-
 
NC_008322  Shewmr7_3549  response regulator receiver modulated metal dependent phosphohydrolase  41.64 
 
 
348 aa  224  2e-57  Shewanella sp. MR-7  Bacteria  normal  normal 
 
 
-
 
NC_008577  Shewana3_0479  response regulator receiver modulated metal dependent phosphohydrolase  41.64 
 
 
350 aa  223  4e-57  Shewanella sp. ANA-3  Bacteria  normal  normal 
 
 
-
 
NC_009943  Dole_1136  response regulator receiver modulated metal dependent phosphohydrolase  37.68 
 
 
348 aa  222  6e-57  Desulfococcus oleovorans Hxd3  Bacteria  normal  n/a   
 
 
-
 
NC_010681  Bphyt_0187  response regulator receiver modulated metal dependent phosphohydrolase  44.68 
 
 
354 aa  221  9.999999999999999e-57  Burkholderia phytofirmans PsJN  Bacteria  normal  normal  0.0125166 
 
 
-
 
NC_008321  Shewmr4_0481  response regulator receiver modulated metal dependent phosphohydrolase  41.28 
 
 
348 aa  221  9.999999999999999e-57  Shewanella sp. MR-4  Bacteria  normal  normal 
 
 
-
 
NC_008228  Patl_2248  response regulator receiver modulated metal dependent phosphohydrolase  37.5 
 
 
331 aa  220  1.9999999999999999e-56  Pseudoalteromonas atlantica T6c  Bacteria  normal  n/a   
 
 
-
 
NC_008321  Shewmr4_0792  response regulator receiver modulated metal dependent phosphohydrolase  40.21 
 
 
331 aa  221  1.9999999999999999e-56  Shewanella sp. MR-4  Bacteria  normal  normal 
 
 
-
 
NC_008322  Shewmr7_3231  response regulator receiver modulated metal dependent phosphohydrolase  40.21 
 
 
331 aa  221  1.9999999999999999e-56  Shewanella sp. MR-7  Bacteria  normal  normal 
 
 
-
 
NC_007954  Sden_0663  response regulator receiver  41.34 
 
 
340 aa  220  3e-56  Shewanella denitrificans OS217  Bacteria  normal  n/a   
 
 
-
 
NC_009972  Haur_1474  response regulator receiver modulated metal dependent phosphohydrolase  44.17 
 
 
345 aa  220  3e-56  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  n/a   
 
 
-
 
NC_013173  Dbac_2017  response regulator receiver modulated metal dependent phosphohydrolase  36.15 
 
 
379 aa  220  3e-56  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  0.98115  n/a   
 
 
-
 
NC_009654  Mmwyl1_0356  response regulator receiver modulated metal dependent phosphohydrolase  38.42 
 
 
360 aa  219  3.9999999999999997e-56  Marinomonas sp. MWYL1  Bacteria  normal  normal 
 
 
-
 
NC_008740  Maqu_3676  response regulator receiver modulated metal dependent phosphohydrolase  40.95 
 
 
328 aa  218  1e-55  Marinobacter aquaeolei VT8  Bacteria  normal  n/a   
 
 
-
 
NC_011138  MADE_03429  two-component system response regulator (hybrid family) protein  37.46 
 
 
358 aa  218  1e-55  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  n/a   
 
 
-
 
NC_011831  Cagg_0863  response regulator receiver modulated metal dependent phosphohydrolase  42.37 
 
 
351 aa  217  2e-55  Chloroflexus aggregans DSM 9485  Bacteria  normal  0.297515  normal  0.141829 
 
 
-
 
NC_007520  Tcr_1911  response regulator receiver (CheY-like) modulated metal dependent phosphohydrolase  43.92 
 
 
268 aa  217  2.9999999999999998e-55  Thiomicrospira crunogena XCL-2  Bacteria  normal  0.0445959  n/a   
 
 
-
 
NC_007298  Daro_3285  response regulator receiver  39.09 
 
 
362 aa  216  4e-55  Dechloromonas aromatica RCB  Bacteria  normal  normal 
 
 
-
 
NC_007954  Sden_3723  response regulator receiver  36.6 
 
 
338 aa  216  4e-55  Shewanella denitrificans OS217  Bacteria  normal  n/a   
 
 
-
 
NC_008700  Sama_2951  response regulator receiver protein  40.69 
 
 
340 aa  216  4e-55  Shewanella amazonensis SB2B  Bacteria  normal  normal  0.129077 
 
 
-
 
NC_008345  Sfri_2505  response regulator receiver modulated metal dependent phosphohydrolase  37.87 
 
 
331 aa  214  9.999999999999999e-55  Shewanella frigidimarina NCIMB 400  Bacteria  normal  n/a   
 
 
-
 
NC_004347  SO_4003  response regulator  41.2 
 
 
357 aa  214  1.9999999999999998e-54  Shewanella oneidensis MR-1  Bacteria  n/a    n/a   
 
 
-
 
NC_008577  Shewana3_3334  response regulator receiver modulated metal dependent phosphohydrolase  39.86 
 
 
331 aa  214  1.9999999999999998e-54  Shewanella sp. ANA-3  Bacteria  normal  normal 
 
 
-
 
NC_002939  GSU1891  response regulator  40.32 
 
 
379 aa  213  4.9999999999999996e-54  Geobacter sulfurreducens PCA  Bacteria  normal  0.750204  n/a   
 
 
-
 
NC_008576  Mmc1_2945  response regulator receiver modulated metal dependent phosphohydrolase  38.44 
 
 
377 aa  212  7e-54  Magnetococcus sp. MC-1  Bacteria  normal  normal 
 
 
-
 
NC_012560  Avin_25160  response regulator  39.67 
 
 
356 aa  211  2e-53  Azotobacter vinelandii DJ  Bacteria  normal  n/a   
 
 
-
 
NC_013552  DhcVS_1406  response regulator  36.71 
 
 
351 aa  211  2e-53  Dehalococcoides sp. VS  Bacteria  normal  n/a   
 
 
-
 
NC_003910  CPS_4164  response regulator/phosphatase  40.77 
 
 
352 aa  209  4e-53  Colwellia psychrerythraea 34H  Bacteria  normal  n/a   
 
 
-
 
NC_007575  Suden_1924  response regulator receiver (CheY-like) modulated metal dependent phosphohydrolase  36.6 
 
 
367 aa  209  7e-53  Sulfurimonas denitrificans DSM 1251  Bacteria  normal  0.620973  n/a   
 
 
-
 
NC_008700  Sama_3111  response regulator receiver protein  38.46 
 
 
328 aa  208  1e-52  Shewanella amazonensis SB2B  Bacteria  normal  normal  0.0637882 
 
 
-
 
NC_011138  MADE_01756  Response regulator CheB (receptor modification enzyme, protein-glutamate methylesterase)  35.71 
 
 
337 aa  206  4e-52  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  0.844049  n/a   
 
 
-
 
NC_009654  Mmwyl1_2382  response regulator receiver modulated metal dependent phosphohydrolase  34.82 
 
 
359 aa  205  9e-52  Marinomonas sp. MWYL1  Bacteria  normal  normal 
 
 
-
 
NC_007298  Daro_3458  response regulator receiver  38.97 
 
 
365 aa  204  2e-51  Dechloromonas aromatica RCB  Bacteria  normal  normal 
 
 
-
 
NC_008576  Mmc1_3072  response regulator receiver modulated metal dependent phosphohydrolase  37.33 
 
 
353 aa  204  2e-51  Magnetococcus sp. MC-1  Bacteria  normal  hitchhiker  0.000480818 
 
 
-
 
NC_011146  Gbem_0080  response regulator receiver modulated metal dependent phosphohydrolase  37.57 
 
 
357 aa  203  3e-51  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_011769  DvMF_1097  response regulator receiver modulated metal dependent phosphohydrolase  35.23 
 
 
391 aa  201  9.999999999999999e-51  Desulfovibrio vulgaris str. 'Miyazaki F'  Bacteria  n/a    normal  0.151318 
 
 
-
 
NC_010717  PXO_00476  two-component system regulatory protein with HD-GYP domain  38.54 
 
 
322 aa  201  9.999999999999999e-51  Xanthomonas oryzae pv. oryzae PXO99A  Bacteria  normal  n/a   
 
 
-
 
NC_010524  Lcho_1463  response regulator receiver modulated metal dependent phosphohydrolase  37.97 
 
 
364 aa  201  9.999999999999999e-51  Leptothrix cholodnii SP-6  Bacteria  n/a    normal  0.404054 
 
 
-
 
NC_012918  GM21_0063  response regulator receiver modulated metal dependent phosphohydrolase  37.69 
 
 
357 aa  201  1.9999999999999998e-50  Geobacter sp. M21  Bacteria  n/a    hitchhiker  2.56416e-22 
 
 
-
 
NC_009483  Gura_4270  response regulator receiver modulated metal dependent phosphohydrolase  37.62 
 
 
361 aa  197  2.0000000000000003e-49  Geobacter uraniireducens Rf4  Bacteria  normal  n/a   
 
 
-
 
NC_014148  Plim_0679  response regulator receiver  37.5 
 
 
337 aa  197  2.0000000000000003e-49  Planctomyces limnophilus DSM 3776  Bacteria  normal  0.0836964  n/a   
 
 
-
 
NC_011662  Tmz1t_2833  response regulator receiver modulated metal dependent phosphohydrolase  40.6 
 
 
360 aa  196  3e-49  Thauera sp. MZ1T  Bacteria  normal  0.809465  n/a   
 
 
-
 
NC_008752  Aave_2064  response regulator receiver modulated metal dependent phosphohydrolase  36.95 
 
 
395 aa  196  4.0000000000000005e-49  Acidovorax citrulli AAC00-1  Bacteria  normal  0.18463  normal  0.544249 
 
 
-
 
NC_008782  Ajs_1044  response regulator receiver modulated metal dependent phosphohydrolase  36.95 
 
 
377 aa  196  6e-49  Acidovorax sp. JS42  Bacteria  normal  normal  0.0516082 
 
 
-
 
NC_011992  Dtpsy_0962  response regulator receiver modulated metal dependent phosphohydrolase  38.31 
 
 
377 aa  195  1e-48  Acidovorax ebreus TPSY  Bacteria  normal  0.115091  n/a   
 
 
-
 
NC_007348  Reut_B4068  response regulator receiver  36.97 
 
 
377 aa  194  2e-48  Ralstonia eutropha JMP134  Bacteria  normal  0.706307  n/a   
 
 
-
 
NC_011769  DvMF_2545  metal dependent phosphohydrolase  58.24 
 
 
269 aa  194  2e-48  Desulfovibrio vulgaris str. 'Miyazaki F'  Bacteria  n/a    normal 
 
 
-
 
NC_008010  Dgeo_2833  metal dependent phosphohydrolase  55.74 
 
 
379 aa  192  5e-48  Deinococcus geothermalis DSM 11300  Bacteria  normal  0.0209293  n/a   
 
 
-
 
NC_013173  Dbac_2325  response regulator receiver modulated metal dependent phosphohydrolase  36.62 
 
 
362 aa  191  1e-47  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  0.663275  n/a   
 
 
-
 
NC_013522  Taci_1744  response regulator receiver modulated metal dependent phosphohydrolase  35.99 
 
 
373 aa  191  2e-47  Thermanaerovibrio acidaminovorans DSM 6589  Bacteria  normal  n/a   
 
 
-
 
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