More than 300 homologs were found in PanDaTox collection
for query gene Dvul_2709 on replicon NC_008751
Organism: Desulfovibrio vulgaris DP4



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_008751  Dvul_2709  response regulator receiver sensor signal transduction histidine kinase  100 
 
 
501 aa  970    Desulfovibrio vulgaris DP4  Bacteria  normal  0.710197  normal  0.745824 
 
 
-
 
NC_011769  DvMF_2549  response regulator receiver sensor signal transduction histidine kinase  65.7 
 
 
446 aa  330  3e-89  Desulfovibrio vulgaris str. 'Miyazaki F'  Bacteria  n/a    normal 
 
 
-
 
NC_007519  Dde_3717  response regulator receiver sensor signal transduction histidine kinase  49.85 
 
 
401 aa  283  5.000000000000001e-75  Desulfovibrio desulfuricans subsp. desulfuricans str. G20  Bacteria  normal  n/a   
 
 
-
 
NC_011769  DvMF_2550  multi-sensor signal transduction histidine kinase  54.24 
 
 
685 aa  171  2e-41  Desulfovibrio vulgaris str. 'Miyazaki F'  Bacteria  n/a    normal 
 
 
-
 
NC_007519  Dde_3715  multi-sensor signal transduction histidine kinase  50 
 
 
653 aa  162  9e-39  Desulfovibrio desulfuricans subsp. desulfuricans str. G20  Bacteria  normal  n/a   
 
 
-
 
NC_013223  Dret_0868  multi-sensor signal transduction histidine kinase  49.12 
 
 
650 aa  155  1e-36  Desulfohalobium retbaense DSM 5692  Bacteria  normal  normal 
 
 
-
 
NC_008751  Dvul_2720  multi-sensor signal transduction histidine kinase  47.13 
 
 
657 aa  152  1e-35  Desulfovibrio vulgaris DP4  Bacteria  normal  normal  0.312815 
 
 
-
 
NC_011146  Gbem_1662  response regulator receiver sensor signal transduction histidine kinase  28.65 
 
 
396 aa  135  1.9999999999999998e-30  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_012918  GM21_2551  response regulator receiver sensor signal transduction histidine kinase  28.65 
 
 
396 aa  134  3e-30  Geobacter sp. M21  Bacteria  n/a    hitchhiker  1.14529e-19 
 
 
-
 
NC_009483  Gura_2932  response regulator receiver sensor signal transduction histidine kinase  27.49 
 
 
394 aa  125  2e-27  Geobacter uraniireducens Rf4  Bacteria  hitchhiker  0.000000651793  n/a   
 
 
-
 
NC_007517  Gmet_2677  response regulator receiver sensor signal transduction histidine kinase  30.43 
 
 
395 aa  122  1.9999999999999998e-26  Geobacter metallireducens GS-15  Bacteria  normal  0.971959  normal  0.344308 
 
 
-
 
NC_010814  Glov_3601  response regulator receiver sensor signal transduction histidine kinase  30.23 
 
 
399 aa  122  1.9999999999999998e-26  Geobacter lovleyi SZ  Bacteria  normal  n/a   
 
 
-
 
NC_007498  Pcar_2015  two component hybrid sensor response regulator  28.08 
 
 
391 aa  120  3.9999999999999996e-26  Pelobacter carbinolicus DSM 2380  Bacteria  normal  n/a   
 
 
-
 
NC_008751  Dvul_2371  response regulator receiver protein  42.86 
 
 
233 aa  120  3.9999999999999996e-26  Desulfovibrio vulgaris DP4  Bacteria  normal  normal 
 
 
-
 
NC_011369  Rleg2_3169  two component, sigma54 specific, transcriptional regulator, Fis family  42.51 
 
 
444 aa  118  1.9999999999999998e-25  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  0.254755  normal  0.187976 
 
 
-
 
NC_007519  Dde_1522  histidine kinase  31.05 
 
 
544 aa  118  3e-25  Desulfovibrio desulfuricans subsp. desulfuricans str. G20  Bacteria  normal  n/a   
 
 
-
 
NC_007519  Dde_0710  response regulator receiver domain-containing protein  43.31 
 
 
240 aa  117  5e-25  Desulfovibrio desulfuricans subsp. desulfuricans str. G20  Bacteria  normal  n/a   
 
 
-
 
NC_009972  Haur_2366  two component, sigma54 specific, Fis family transcriptional regulator  49.57 
 
 
385 aa  117  6e-25  Herpetosiphon aurantiacus ATCC 23779  Bacteria  hitchhiker  0.0000342445  n/a   
 
 
-
 
NC_008554  Sfum_2764  two component, sigma54 specific, Fis family transcriptional regulator  43.66 
 
 
466 aa  117  6e-25  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  normal 
 
 
-
 
NC_002939  GSU1119  sensor histidine kinase/response regulator  26.49 
 
 
420 aa  116  7.999999999999999e-25  Geobacter sulfurreducens PCA  Bacteria  normal  n/a   
 
 
-
 
NC_012850  Rleg_3460  two component, sigma54 specific, transcriptional regulator, Fis family  41.32 
 
 
444 aa  116  8.999999999999998e-25  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  0.0376131  normal 
 
 
-
 
NC_011769  DvMF_0064  histidine kinase  31.23 
 
 
598 aa  114  5e-24  Desulfovibrio vulgaris str. 'Miyazaki F'  Bacteria  n/a    normal 
 
 
-
 
NC_008609  Ppro_2968  response regulator receiver sensor signal transduction histidine kinase  28.37 
 
 
392 aa  114  6e-24  Pelobacter propionicus DSM 2379  Bacteria  normal  n/a   
 
 
-
 
NC_009943  Dole_1777  two component, sigma54 specific, Fis family transcriptional regulator  43.41 
 
 
465 aa  112  1.0000000000000001e-23  Desulfococcus oleovorans Hxd3  Bacteria  normal  n/a   
 
 
-
 
NC_013173  Dbac_0976  anti-sigma-factor antagonist  40.6 
 
 
237 aa  111  4.0000000000000004e-23  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  n/a   
 
 
-
 
NC_007517  Gmet_0010  PAS/PAC sensor hybrid histidine kinase  36.31 
 
 
508 aa  109  1e-22  Geobacter metallireducens GS-15  Bacteria  normal  0.0502065  normal 
 
 
-
 
NC_009675  Anae109_2440  response regulator receiver sensor signal transduction histidine kinase  31.75 
 
 
375 aa  109  1e-22  Anaeromyxobacter sp. Fw109-5  Bacteria  normal  0.467167  normal  0.627522 
 
 
-
 
NC_008009  Acid345_2498  response regulator receiver modulated metal dependent phosphohydrolase  40.14 
 
 
367 aa  109  1e-22  Candidatus Koribacter versatilis Ellin345  Bacteria  normal  normal  0.751736 
 
 
-
 
NC_011146  Gbem_3634  response regulator receiver sensor signal transduction histidine kinase  29.01 
 
 
379 aa  108  2e-22  Geobacter bemidjiensis Bem  Bacteria  normal  0.0261897  n/a   
 
 
-
 
NC_007498  Pcar_1960  response regulator transcription factor  40.65 
 
 
471 aa  108  2e-22  Pelobacter carbinolicus DSM 2380  Bacteria  normal  n/a   
 
 
-
 
NC_011830  Dhaf_4779  two component, sigma54 specific, transcriptional regulator, Fis family  43.33 
 
 
494 aa  108  2e-22  Desulfitobacterium hafniense DCB-2  Bacteria  normal  n/a   
 
 
-
 
NC_013173  Dbac_2828  response regulator receiver sensor signal transduction histidine kinase  29.15 
 
 
410 aa  108  2e-22  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  n/a   
 
 
-
 
NC_011769  DvMF_1544  response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)  41.38 
 
 
739 aa  108  3e-22  Desulfovibrio vulgaris str. 'Miyazaki F'  Bacteria  n/a    normal  0.498595 
 
 
-
 
NC_011769  DvMF_1223  anti-sigma-factor antagonist  48.78 
 
 
271 aa  107  5e-22  Desulfovibrio vulgaris str. 'Miyazaki F'  Bacteria  n/a    normal  0.068542 
 
 
-
 
NC_011145  AnaeK_2031  response regulator receiver modulated metal dependent phosphohydrolase  42.76 
 
 
357 aa  107  6e-22  Anaeromyxobacter sp. K  Bacteria  normal  0.306573  n/a   
 
 
-
 
NC_012918  GM21_0063  response regulator receiver modulated metal dependent phosphohydrolase  38.36 
 
 
357 aa  107  6e-22  Geobacter sp. M21  Bacteria  n/a    hitchhiker  2.56416e-22 
 
 
-
 
NC_011891  A2cp1_2101  response regulator receiver modulated metal dependent phosphohydrolase  42.76 
 
 
357 aa  107  6e-22  Anaeromyxobacter dehalogenans 2CP-1  Bacteria  normal  n/a   
 
 
-
 
NC_007760  Adeh_1829  response regulator receiver (CheY-like) modulated metal dependent phosphohydrolase  42.76 
 
 
357 aa  107  6e-22  Anaeromyxobacter dehalogenans 2CP-C  Bacteria  normal  n/a   
 
 
-
 
NC_013223  Dret_0548  two component, sigma54 specific, transcriptional regulator, Fis family  43.44 
 
 
452 aa  107  6e-22  Desulfohalobium retbaense DSM 5692  Bacteria  normal  0.902927  normal 
 
 
-
 
NC_002939  GSU0372  sigma-54 dependent DNA-binding response regulator  44.36 
 
 
461 aa  107  7e-22  Geobacter sulfurreducens PCA  Bacteria  normal  n/a   
 
 
-
 
NC_007519  Dde_3003  two component Fis family transcriptional regulator  43.61 
 
 
465 aa  107  7e-22  Desulfovibrio desulfuricans subsp. desulfuricans str. G20  Bacteria  normal  0.0697126  n/a   
 
 
-
 
NC_013440  Hoch_3222  two component, sigma54 specific, transcriptional regulator, Fis family  47.97 
 
 
447 aa  107  7e-22  Haliangium ochraceum DSM 14365  Bacteria  normal  normal  0.0905113 
 
 
-
 
NC_009675  Anae109_1991  response regulator receiver modulated metal dependent phosphohydrolase  38.01 
 
 
357 aa  106  9e-22  Anaeromyxobacter sp. Fw109-5  Bacteria  normal  normal 
 
 
-
 
NC_014148  Plim_2084  sigma-54 factor interaction domain-containing protein  42.28 
 
 
477 aa  105  1e-21  Planctomyces limnophilus DSM 3776  Bacteria  normal  0.327808  n/a   
 
 
-
 
NC_014150  Bmur_0931  response regulator receiver protein  40.52 
 
 
430 aa  105  1e-21  Brachyspira murdochii DSM 12563  Bacteria  normal  n/a   
 
 
-
 
NC_013223  Dret_0410  anti-sigma-factor antagonist  44.44 
 
 
238 aa  106  1e-21  Desulfohalobium retbaense DSM 5692  Bacteria  normal  normal  0.694521 
 
 
-
 
NC_008554  Sfum_0828  multi-sensor signal transduction histidine kinase  38.89 
 
 
567 aa  106  1e-21  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  normal 
 
 
-
 
NC_011146  Gbem_0080  response regulator receiver modulated metal dependent phosphohydrolase  37.67 
 
 
357 aa  106  1e-21  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_002939  GSU0008  sensory box histidine kinase/response regulator  36.3 
 
 
516 aa  105  2e-21  Geobacter sulfurreducens PCA  Bacteria  normal  n/a   
 
 
-
 
NC_010814  Glov_1377  two component, sigma54 specific, transcriptional regulator, Fis family  41.79 
 
 
462 aa  105  2e-21  Geobacter lovleyi SZ  Bacteria  normal  0.244526  n/a   
 
 
-
 
NC_009483  Gura_0925  two component, sigma-54 specific, Fis family transcriptional regulator  36.07 
 
 
500 aa  105  2e-21  Geobacter uraniireducens Rf4  Bacteria  normal  n/a   
 
 
-
 
NC_013173  Dbac_2666  two component, sigma54 specific, transcriptional regulator, Fis family  45.11 
 
 
459 aa  105  2e-21  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  n/a   
 
 
-
 
NC_013440  Hoch_5989  two component, sigma54 specific, transcriptional regulator, Fis family  43.38 
 
 
459 aa  105  2e-21  Haliangium ochraceum DSM 14365  Bacteria  normal  0.999422  normal 
 
 
-
 
NC_002936  DET0624  response regulator  34.04 
 
 
334 aa  104  3e-21  Dehalococcoides ethenogenes 195  Bacteria  normal  n/a   
 
 
-
 
NC_011769  DvMF_1461  two component, sigma54 specific, transcriptional regulator, Fis family  46.51 
 
 
491 aa  104  3e-21  Desulfovibrio vulgaris str. 'Miyazaki F'  Bacteria  n/a    normal  0.750458 
 
 
-
 
NC_013552  DhcVS_1406  response regulator  41.84 
 
 
351 aa  105  3e-21  Dehalococcoides sp. VS  Bacteria  normal  n/a   
 
 
-
 
NC_011757  Mchl_3285  two component, sigma54 specific, transcriptional regulator, Fis family  44.85 
 
 
450 aa  104  3e-21  Methylobacterium chloromethanicum CM4  Bacteria  normal  normal 
 
 
-
 
NC_009675  Anae109_0684  two component, sigma54 specific, Fis family transcriptional regulator  43.28 
 
 
456 aa  104  4e-21  Anaeromyxobacter sp. Fw109-5  Bacteria  normal  normal 
 
 
-
 
NC_009943  Dole_1351  response regulator receiver protein  43.55 
 
 
141 aa  103  6e-21  Desulfococcus oleovorans Hxd3  Bacteria  hitchhiker  0.000171187  n/a   
 
 
-
 
NC_013223  Dret_0200  two component, sigma54 specific, transcriptional regulator, Fis family  37.5 
 
 
449 aa  103  8e-21  Desulfohalobium retbaense DSM 5692  Bacteria  normal  normal 
 
 
-
 
NC_009483  Gura_0495  two component, sigma-54 specific, Fis family transcriptional regulator  40 
 
 
456 aa  103  8e-21  Geobacter uraniireducens Rf4  Bacteria  normal  n/a   
 
 
-
 
NC_009455  DehaBAV1_0597  response regulator receiver modulated metal dependent phosphohydrolase  34.75 
 
 
334 aa  103  8e-21  Dehalococcoides sp. BAV1  Bacteria  normal  n/a   
 
 
-
 
NC_010172  Mext_3061  sigma-54 factor interaction domain-containing protein  44.12 
 
 
450 aa  103  8e-21  Methylobacterium extorquens PA1  Bacteria  normal  0.305462  normal 
 
 
-
 
NC_012918  GM21_0962  two component, sigma54 specific, transcriptional regulator, Fis family  45.83 
 
 
458 aa  103  8e-21  Geobacter sp. M21  Bacteria  n/a    normal  0.277353 
 
 
-
 
NC_009767  Rcas_1114  response regulator receiver modulated serine phosphatase  43.94 
 
 
391 aa  103  9e-21  Roseiflexus castenholzii DSM 13941  Bacteria  normal  normal 
 
 
-
 
NC_011146  Gbem_3286  two component, sigma54 specific, transcriptional regulator, Fis family  45.83 
 
 
458 aa  103  9e-21  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_011891  A2cp1_0673  two component, sigma54 specific, transcriptional regulator, Fis family  44.19 
 
 
458 aa  102  1e-20  Anaeromyxobacter dehalogenans 2CP-1  Bacteria  normal  n/a   
 
 
-
 
NC_007760  Adeh_0417  two component, sigma54 specific, Fis family transcriptional regulator  40.98 
 
 
474 aa  103  1e-20  Anaeromyxobacter dehalogenans 2CP-C  Bacteria  normal  0.45134  n/a   
 
 
-
 
NC_007760  Adeh_0639  two component, sigma54 specific, Fis family transcriptional regulator  44.96 
 
 
455 aa  102  1e-20  Anaeromyxobacter dehalogenans 2CP-C  Bacteria  normal  n/a   
 
 
-
 
NC_011769  DvMF_2679  two component, sigma54 specific, transcriptional regulator, Fis family  39.76 
 
 
486 aa  102  1e-20  Desulfovibrio vulgaris str. 'Miyazaki F'  Bacteria  n/a    normal  0.319369 
 
 
-
 
NC_008751  Dvul_0403  response regulator receiver sensor signal transduction histidine kinase  31.51 
 
 
374 aa  102  1e-20  Desulfovibrio vulgaris DP4  Bacteria  normal  normal  0.150899 
 
 
-
 
NC_002939  GSU1320  sigma-54 dependent DNA-binding response regulator  40.58 
 
 
460 aa  102  2e-20  Geobacter sulfurreducens PCA  Bacteria  normal  n/a   
 
 
-
 
NC_011145  AnaeK_0445  two component, sigma54 specific, transcriptional regulator, Fis family  40.65 
 
 
481 aa  102  2e-20  Anaeromyxobacter sp. K  Bacteria  normal  n/a   
 
 
-
 
NC_012918  GM21_3739  response regulator receiver sensor signal transduction histidine kinase  29.72 
 
 
379 aa  102  2e-20  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_011146  Gbem_3819  two component, sigma54 specific, transcriptional regulator, Fis family  41.38 
 
 
455 aa  102  2e-20  Geobacter bemidjiensis Bem  Bacteria  normal  0.785821  n/a   
 
 
-
 
NC_007760  Adeh_1055  two component, sigma54 specific, Fis family transcriptional regulator  42.52 
 
 
481 aa  102  2e-20  Anaeromyxobacter dehalogenans 2CP-C  Bacteria  normal  0.874499  n/a   
 
 
-
 
NC_009636  Smed_1092  two component, sigma54 specific, Fis family transcriptional regulator  41.6 
 
 
454 aa  102  2e-20  Sinorhizobium medicae WSM419  Bacteria  normal  0.452222  normal 
 
 
-
 
NC_011145  AnaeK_0673  two component, sigma54 specific, transcriptional regulator, Fis family  44.19 
 
 
457 aa  102  2e-20  Anaeromyxobacter sp. K  Bacteria  normal  n/a   
 
 
-
 
NC_011891  A2cp1_0446  two component, sigma54 specific, transcriptional regulator, Fis family  40.65 
 
 
481 aa  102  2e-20  Anaeromyxobacter dehalogenans 2CP-1  Bacteria  normal  n/a   
 
 
-
 
NC_009675  Anae109_1105  two component, sigma54 specific, Fis family transcriptional regulator  37.22 
 
 
475 aa  102  2e-20  Anaeromyxobacter sp. Fw109-5  Bacteria  normal  0.926771  normal  0.835973 
 
 
-
 
NC_013132  Cpin_6438  putative two component, sigma54 specific, transcriptional regulator, Fis family  39.67 
 
 
394 aa  101  3e-20  Chitinophaga pinensis DSM 2588  Bacteria  decreased coverage  0.00615091  normal  0.383003 
 
 
-
 
NC_011145  AnaeK_0313  two component, sigma54 specific, transcriptional regulator, Fis family  46.4 
 
 
465 aa  101  3e-20  Anaeromyxobacter sp. K  Bacteria  normal  0.0494225  n/a   
 
 
-
 
NC_007492  Pfl01_4550  response regulator receiver domain-containing protein  33.47 
 
 
451 aa  101  3e-20  Pseudomonas fluorescens Pf0-1  Bacteria  normal  0.01769  normal 
 
 
-
 
NC_011891  A2cp1_1183  two component, sigma54 specific, transcriptional regulator, Fis family  36.81 
 
 
481 aa  101  3e-20  Anaeromyxobacter dehalogenans 2CP-1  Bacteria  normal  n/a   
 
 
-
 
NC_012918  GM21_3903  two component, sigma54 specific, transcriptional regulator, Fis family  36.09 
 
 
455 aa  101  3e-20  Geobacter sp. M21  Bacteria  n/a    hitchhiker  0.000574971 
 
 
-
 
NC_008254  Meso_1616  two component, sigma54 specific, Fis family transcriptional regulator  43.44 
 
 
453 aa  101  3e-20  Chelativorans sp. BNC1  Bacteria  normal  n/a   
 
 
-
 
NC_011145  AnaeK_1114  two component, sigma54 specific, transcriptional regulator, Fis family  36.81 
 
 
501 aa  101  3e-20  Anaeromyxobacter sp. K  Bacteria  normal  n/a   
 
 
-
 
NC_010725  Mpop_3260  two component, sigma54 specific, transcriptional regulator, Fis family  43.26 
 
 
450 aa  101  4e-20  Methylobacterium populi BJ001  Bacteria  normal  normal 
 
 
-
 
NC_011891  A2cp1_0324  two component, sigma54 specific, transcriptional regulator, Fis family  46.4 
 
 
465 aa  101  4e-20  Anaeromyxobacter dehalogenans 2CP-1  Bacteria  normal  0.266606  n/a   
 
 
-
 
NC_007517  Gmet_2453  two component, sigma54 specific, Fis family transcriptional regulator  43.97 
 
 
461 aa  101  4e-20  Geobacter metallireducens GS-15  Bacteria  hitchhiker  0.0000196128  normal 
 
 
-
 
NC_009675  Anae109_4152  two component, sigma54 specific, Fis family transcriptional regulator  40.83 
 
 
480 aa  100  4e-20  Anaeromyxobacter sp. Fw109-5  Bacteria  normal  normal  0.038607 
 
 
-
 
NC_010322  PputGB1_4410  two component, sigma54 specific, Fis family transcriptional regulator  36.7 
 
 
444 aa  101  4e-20  Pseudomonas putida GB-1  Bacteria  normal  normal 
 
 
-
 
NC_002939  GSU1495  sigma-54 dependent DNA-binding response regulator  40.31 
 
 
458 aa  100  6e-20  Geobacter sulfurreducens PCA  Bacteria  normal  0.301103  n/a   
 
 
-
 
NC_011146  Gbem_3413  two component, sigma54 specific, transcriptional regulator, Fis family  38.57 
 
 
453 aa  100  6e-20  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_013173  Dbac_3323  two component, sigma54 specific, transcriptional regulator, Fis family  33.58 
 
 
458 aa  100  6e-20  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  0.581416  n/a   
 
 
-
 
NC_010511  M446_4770  two component, sigma54 specific, Fis family transcriptional regulator  45.93 
 
 
446 aa  100  6e-20  Methylobacterium sp. 4-46  Bacteria  normal  0.133057  normal  0.593625 
 
 
-
 
NC_009675  Anae109_4257  two component, sigma54 specific, Fis family transcriptional regulator  45.97 
 
 
463 aa  100  6e-20  Anaeromyxobacter sp. Fw109-5  Bacteria  normal  normal 
 
 
-
 
NC_013552  DhcVS_565  response regulator receiver:metal-dependent phosphohydrolase, HD subdomain protein  34.04 
 
 
334 aa  100  6e-20  Dehalococcoides sp. VS  Bacteria  normal  n/a   
 
 
-
 
NC_013173  Dbac_1807  response regulator receiver protein  42.62 
 
 
139 aa  100  7e-20  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  n/a   
 
 
-
 
NC_011769  DvMF_1260  two component, sigma54 specific, transcriptional regulator, Fis family  41.18 
 
 
452 aa  100  7e-20  Desulfovibrio vulgaris str. 'Miyazaki F'  Bacteria  n/a    hitchhiker  0.0000000000141339 
 
 
-
 
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