237 homologs were found in PanDaTox collection
for query gene TDE1667 on replicon NC_002967
Organism: Treponema denticola ATCC 35405



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_002967  TDE1667  methylthioribose-1-phosphate isomerase  100 
 
 
352 aa  726    Treponema denticola ATCC 35405  Bacteria  hitchhiker  0.0000944772  n/a   
 
 
-
 
NC_014150  Bmur_0775  eIF-2B alpha/beta/delta-related uncharacterized protein  47.85 
 
 
357 aa  331  1e-89  Brachyspira murdochii DSM 12563  Bacteria  normal  0.369946  n/a   
 
 
-
 
NC_013947  Snas_2276  eIF-2B alpha/beta/delta-related uncharacterized protein  40.18 
 
 
348 aa  241  1e-62  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  normal 
 
 
-
 
NC_013757  Gobs_3385  eIF-2B alpha/beta/delta-related uncharacterized protein  39.4 
 
 
357 aa  232  7.000000000000001e-60  Geodermatophilus obscurus DSM 43160  Bacteria  normal  n/a   
 
 
-
 
NC_013093  Amir_0984  eIF-2B alpha/beta/delta-related uncharacterized protein  35.47 
 
 
343 aa  212  7e-54  Actinosynnema mirum DSM 43827  Bacteria  normal  n/a   
 
 
-
 
NC_009253  Dred_1773  eIF-2B alpha/beta/delta-related uncharacterized protein  36.17 
 
 
343 aa  191  1e-47  Desulfotomaculum reducens MI-1  Bacteria  normal  n/a   
 
 
-
 
NC_009972  Haur_4869  eIF-2B alpha/beta/delta-related uncharacterized protein  34.82 
 
 
359 aa  187  3e-46  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  n/a   
 
 
-
 
NC_009616  Tmel_0254  aIF-2BI family translation initiation factor  35.78 
 
 
346 aa  171  3e-41  Thermosipho melanesiensis BI429  Bacteria  normal  n/a   
 
 
-
 
NC_009718  Fnod_1519  aIF-2BI family translation initiation factor  35.8 
 
 
350 aa  168  1e-40  Fervidobacterium nodosum Rt17-B1  Bacteria  normal  0.889993  n/a   
 
 
-
 
NC_011899  Hore_18480  putative translation initiation factor, aIF-2BI family  35.61 
 
 
355 aa  166  5e-40  Halothermothrix orenii H 168  Bacteria  normal  0.0224403  n/a   
 
 
-
 
NC_010483  TRQ2_0016  aIF-2BI family translation initiation factor  35.4 
 
 
343 aa  164  2.0000000000000002e-39  Thermotoga sp. RQ2  Bacteria  normal  0.570831  n/a   
 
 
-
 
NC_009486  Tpet_0016  aIF-2BI family translation initiation factor  35.4 
 
 
343 aa  164  2.0000000000000002e-39  Thermotoga petrophila RKU-1  Bacteria  normal  0.339634  n/a   
 
 
-
 
NC_010003  Pmob_0810  aIF-2BI family translation initiation factor  32.94 
 
 
349 aa  162  1e-38  Petrotoga mobilis SJ95  Bacteria  normal  n/a   
 
 
-
 
NC_011661  Dtur_0929  translation initiation factor, aIF-2BI family  35.1 
 
 
344 aa  159  8e-38  Dictyoglomus turgidum DSM 6724  Bacteria  normal  0.119435  n/a   
 
 
-
 
NC_008009  Acid345_1175  translation initiation factor 2B subunit I  33.9 
 
 
354 aa  159  8e-38  Candidatus Koribacter versatilis Ellin345  Bacteria  normal  normal 
 
 
-
 
NC_008698  Tpen_0246  eIF-2B alpha/beta/delta-related uncharacterized proteins  31.82 
 
 
345 aa  158  2e-37  Thermofilum pendens Hrk 5  Archaea  normal  n/a   
 
 
-
 
NC_013440  Hoch_6765  translation initiation factor, aIF-2BI family  32.4 
 
 
369 aa  157  2e-37  Haliangium ochraceum DSM 14365  Bacteria  normal  normal 
 
 
-
 
NC_011831  Cagg_3560  translation initiation factor, aIF-2BI family  33.05 
 
 
357 aa  157  2e-37  Chloroflexus aggregans DSM 9485  Bacteria  normal  normal 
 
 
-
 
NC_012034  Athe_1360  translation initiation factor, aIF-2BI family  34.96 
 
 
342 aa  158  2e-37  Anaerocellum thermophilum DSM 6725  Bacteria  normal  0.0559648  n/a   
 
 
-
 
NC_010424  Daud_0648  aIF-2BI family translation initiation factor  29.86 
 
 
348 aa  156  6e-37  Candidatus Desulforudis audaxviator MP104C  Bacteria  normal  0.674044  n/a   
 
 
-
 
NC_013522  Taci_1036  translation initiation factor, aIF-2BI family  32.85 
 
 
347 aa  153  5e-36  Thermanaerovibrio acidaminovorans DSM 6589  Bacteria  normal  0.313313  n/a   
 
 
-
 
NC_007517  Gmet_0072  translation initiation factor 2B subunit I  32.29 
 
 
346 aa  151  2e-35  Geobacter metallireducens GS-15  Bacteria  normal  normal  0.25912 
 
 
-
 
NC_009675  Anae109_4334  eIF-2B alpha/beta/delta-related uncharacterized protein  32.01 
 
 
337 aa  145  1e-33  Anaeromyxobacter sp. Fw109-5  Bacteria  normal  normal 
 
 
-
 
NC_012793  GWCH70_0846  methylthioribose-1-phosphate isomerase  33.71 
 
 
356 aa  143  5e-33  Geobacillus sp. WCH70  Bacteria  normal  n/a   
 
 
-
 
NC_009253  Dred_2064  aIF-2BI family translation initiation factor  30.43 
 
 
346 aa  143  6e-33  Desulfotomaculum reducens MI-1  Bacteria  unclonable  0.0000000777983  n/a   
 
 
-
 
NC_007908  Rfer_3749  putative translation initiation factor, aIF-2BI/5-methylthioribose-1-phosphate isomerase  29.97 
 
 
354 aa  142  9e-33  Rhodoferax ferrireducens T118  Bacteria  normal  n/a   
 
 
-
 
NC_010814  Glov_3596  translation initiation factor, aIF-2BI family  31.27 
 
 
346 aa  141  1.9999999999999998e-32  Geobacter lovleyi SZ  Bacteria  normal  0.82629  n/a   
 
 
-
 
NC_010320  Teth514_1881  aIF-2BI family translation initiation factor  30.86 
 
 
345 aa  139  4.999999999999999e-32  Thermoanaerobacter sp. X514  Bacteria  normal  n/a   
 
 
-
 
NC_009440  Msed_2269  translation initiation factor 2B subunit I  32.27 
 
 
349 aa  139  4.999999999999999e-32  Metallosphaera sedula DSM 5348  Archaea  normal  normal 
 
 
-
 
CP001800  Ssol_0770  translation initiation factor, aIF-2BI family  32.01 
 
 
366 aa  139  7e-32  Sulfolobus solfataricus 98/2  Archaea  normal  0.301181  n/a   
 
 
-
 
NC_009455  DehaBAV1_0494  translation initiation factor 2B subunit I  30.86 
 
 
332 aa  139  7e-32  Dehalococcoides sp. BAV1  Bacteria  normal  0.93452  n/a   
 
 
-
 
NC_009012  Cthe_0621  translation initiation factor 2B subunit I  31.2 
 
 
342 aa  139  7.999999999999999e-32  Clostridium thermocellum ATCC 27405  Bacteria  normal  0.0997628  n/a   
 
 
-
 
NC_009483  Gura_4322  aIF-2BI family translation initiation factor  30.03 
 
 
346 aa  139  8.999999999999999e-32  Geobacter uraniireducens Rf4  Bacteria  normal  0.394096  n/a   
 
 
-
 
NC_002936  DET0518  aIF-2BI family translation initiation factor  30.26 
 
 
334 aa  138  1e-31  Dehalococcoides ethenogenes 195  Bacteria  normal  0.294825  n/a   
 
 
-
 
NC_013552  DhcVS_459  methylthioribose-1-phosphate isomerase  30.09 
 
 
332 aa  138  1e-31  Dehalococcoides sp. VS  Bacteria  normal  0.14852  n/a   
 
 
-
 
NC_008609  Ppro_0510  aIF-2BI family translation initiation factor  30.7 
 
 
346 aa  138  1e-31  Pelobacter propionicus DSM 2379  Bacteria  normal  n/a   
 
 
-
 
NC_009073  Pcal_2173  translation initiation factor IF-2B subunit alpha  31.67 
 
 
366 aa  138  1e-31  Pyrobaculum calidifontis JCM 11548  Archaea  n/a    normal 
 
 
-
 
NC_002939  GSU3379  aIF-2BI family translation initiation factor  30.59 
 
 
346 aa  137  4e-31  Geobacter sulfurreducens PCA  Bacteria  normal  n/a   
 
 
-
 
NC_010718  Nther_0419  translation initiation factor 2B subunit I family (IF-2BI)  31.4 
 
 
347 aa  136  6.0000000000000005e-31  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  0.04546  normal 
 
 
-
 
NC_010513  Xfasm12_2124  methylthioribose-1-phosphate isomerase  28.87 
 
 
354 aa  136  6.0000000000000005e-31  Xylella fastidiosa M12  Bacteria  normal  0.369854  n/a   
 
 
-
 
NC_008751  Dvul_2877  eIF-2B alpha/beta/delta-related uncharacterized proteins  29.65 
 
 
350 aa  135  8e-31  Desulfovibrio vulgaris DP4  Bacteria  normal  normal 
 
 
-
 
NC_010577  XfasM23_2043  methylthioribose-1-phosphate isomerase  29.17 
 
 
354 aa  135  9e-31  Xylella fastidiosa M23  Bacteria  normal  n/a   
 
 
-
 
NC_013926  Aboo_1543  translation initiation factor, aIF-2BI family  33.04 
 
 
333 aa  134  3e-30  Aciduliprofundum boonei T469  Archaea  normal  0.0321135  n/a   
 
 
-
 
NC_010184  BcerKBAB4_0327  methylthioribose-1-phosphate isomerase  31.73 
 
 
348 aa  134  3e-30  Bacillus weihenstephanensis KBAB4  Bacteria  normal  n/a   
 
 
-
 
NC_011725  BCB4264_A0394  methylthioribose-1-phosphate isomerase  31.05 
 
 
348 aa  133  3.9999999999999996e-30  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_009635  Maeo_0027  aIF-2BI family translation initiation factor  31.28 
 
 
337 aa  133  5e-30  Methanococcus aeolicus Nankai-3  Archaea  normal  n/a   
 
 
-
 
NC_010717  PXO_00735  methylthioribose-1-phosphate isomerase  30.18 
 
 
354 aa  132  6.999999999999999e-30  Xanthomonas oryzae pv. oryzae PXO99A  Bacteria  normal  0.214802  n/a   
 
 
-
 
NC_008576  Mmc1_1944  translation initiation factor 2B subunit I  32.3 
 
 
352 aa  131  1.0000000000000001e-29  Magnetococcus sp. MC-1  Bacteria  hitchhiker  0.00466755  normal  0.570212 
 
 
-
 
NC_010085  Nmar_0169  aIF-2BI family translation initiation factor  32.85 
 
 
345 aa  131  2.0000000000000002e-29  Nitrosopumilus maritimus SCM1  Archaea  n/a    hitchhiker  0.00178496 
 
 
-
 
NC_014150  Bmur_2613  translation initiation factor, aIF-2BI family  31.43 
 
 
349 aa  131  2.0000000000000002e-29  Brachyspira murdochii DSM 12563  Bacteria  normal  n/a   
 
 
-
 
NC_007498  Pcar_2170  aIF-2BI family translation initiation factor  29.39 
 
 
344 aa  131  2.0000000000000002e-29  Pelobacter carbinolicus DSM 2380  Bacteria  normal  n/a   
 
 
-
 
NC_007604  Synpcc7942_1992  translation initiation factor 2B subunit I  29.83 
 
 
348 aa  131  2.0000000000000002e-29  Synechococcus elongatus PCC 7942  Bacteria  normal  normal  0.337411 
 
 
-
 
NC_011658  BCAH187_A0441  methylthioribose-1-phosphate isomerase  31.07 
 
 
348 aa  131  2.0000000000000002e-29  Bacillus cereus AH187  Bacteria  normal  n/a   
 
 
-
 
NC_005945  BAS0332  methylthioribose-1-phosphate isomerase  30.9 
 
 
348 aa  130  3e-29  Bacillus anthracis str. Sterne  Bacteria  normal  n/a   
 
 
-
 
NC_007530  GBAA_0347  methylthioribose-1-phosphate isomerase  30.9 
 
 
347 aa  130  3e-29  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  n/a   
 
 
-
 
NC_011773  BCAH820_0379  methylthioribose-1-phosphate isomerase  30.9 
 
 
348 aa  130  3e-29  Bacillus cereus AH820  Bacteria  n/a    normal 
 
 
-
 
NC_005957  BT9727_0316  methylthioribose-1-phosphate isomerase  30.23 
 
 
348 aa  130  4.0000000000000003e-29  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  n/a   
 
 
-
 
NC_009972  Haur_2349  aIF-2BI family translation initiation factor  29.38 
 
 
358 aa  130  4.0000000000000003e-29  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  0.944221  n/a   
 
 
-
 
NC_014212  Mesil_1647  translation initiation factor, aIF-2BI family  30.37 
 
 
329 aa  130  5.0000000000000004e-29  Meiothermus silvanus DSM 9946  Bacteria  normal  normal 
 
 
-
 
NC_013946  Mrub_0999  aIF-2BI family translation initiation factor  31.25 
 
 
327 aa  129  6e-29  Meiothermus ruber DSM 1279  Bacteria  normal  0.260098  normal 
 
 
-
 
NC_011146  Gbem_3646  translation initiation factor, aIF-2BI family  31.25 
 
 
346 aa  128  1.0000000000000001e-28  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_008346  Swol_0779  S-methyl-5-thioribose-1-phosphate isomerase  30.88 
 
 
346 aa  128  1.0000000000000001e-28  Syntrophomonas wolfei subsp. wolfei str. Goettingen  Bacteria  normal  0.404257  n/a   
 
 
-
 
NC_011772  BCG9842_B4924  methylthioribose-1-phosphate isomerase  30.51 
 
 
348 aa  129  1.0000000000000001e-28  Bacillus cereus G9842  Bacteria  normal  0.64519  normal 
 
 
-
 
NC_006274  BCZK0319  methylthioribose-1-phosphate isomerase  30.88 
 
 
347 aa  128  2.0000000000000002e-28  Bacillus cereus E33L  Bacteria  normal  n/a   
 
 
-
 
NC_011883  Ddes_2312  translation initiation factor, aIF-2BI family  31.41 
 
 
378 aa  127  2.0000000000000002e-28  Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774  Bacteria  normal  n/a   
 
 
-
 
NC_013223  Dret_0503  translation initiation factor, aIF-2BI family  30.26 
 
 
350 aa  128  2.0000000000000002e-28  Desulfohalobium retbaense DSM 5692  Bacteria  normal  normal 
 
 
-
 
NC_012918  GM21_3753  translation initiation factor, aIF-2BI family  31.25 
 
 
346 aa  127  2.0000000000000002e-28  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_013216  Dtox_1186  translation initiation factor, aIF-2BI family  31.91 
 
 
345 aa  128  2.0000000000000002e-28  Desulfotomaculum acetoxidans DSM 771  Bacteria  hitchhiker  0.000144196  normal  0.031954 
 
 
-
 
NC_011769  DvMF_2235  translation initiation factor, aIF-2BI family  28.99 
 
 
350 aa  127  4.0000000000000003e-28  Desulfovibrio vulgaris str. 'Miyazaki F'  Bacteria  n/a    normal 
 
 
-
 
NC_010525  Tneu_0005  translation initiation factor IF-2B subunit alpha  30.86 
 
 
365 aa  126  5e-28  Thermoproteus neutrophilus V24Sta  Archaea  normal  normal 
 
 
-
 
NC_013501  Rmar_1491  translation initiation factor, aIF-2BI family  29.89 
 
 
353 aa  126  6e-28  Rhodothermus marinus DSM 4252  Bacteria  normal  0.626941  n/a   
 
 
-
 
NC_007519  Dde_0076  translation initiation factor 2B subunit I  30.88 
 
 
355 aa  124  2e-27  Desulfovibrio desulfuricans subsp. desulfuricans str. G20  Bacteria  normal  n/a   
 
 
-
 
NC_007796  Mhun_0623  putative translation initiation factor, aIF-2BI/5-methylthioribose-1-phosphate isomerase  30.46 
 
 
354 aa  124  2e-27  Methanospirillum hungatei JF-1  Archaea  normal  0.242304  normal  0.23951 
 
 
-
 
NC_009712  Mboo_1840  aIF-2BI family translation initiation factor  30.68 
 
 
348 aa  124  3e-27  Candidatus Methanoregula boonei 6A8  Archaea  normal  0.635739  normal 
 
 
-
 
NC_009376  Pars_0008  translation initiation factor IF-2B subunit alpha  32.56 
 
 
351 aa  124  3e-27  Pyrobaculum arsenaticum DSM 13514  Archaea  normal  0.679741  normal 
 
 
-
 
NC_007760  Adeh_4186  translation initiation factor 2B subunit I  29.86 
 
 
339 aa  123  4e-27  Anaeromyxobacter dehalogenans 2CP-C  Bacteria  normal  n/a   
 
 
-
 
NC_011830  Dhaf_3765  translation initiation factor, aIF-2BI family  30.12 
 
 
345 aa  123  5e-27  Desulfitobacterium hafniense DCB-2  Bacteria  normal  0.0692423  n/a   
 
 
-
 
NC_011891  A2cp1_4339  translation initiation factor, aIF-2BI family  29.86 
 
 
339 aa  123  5e-27  Anaeromyxobacter dehalogenans 2CP-1  Bacteria  normal  n/a   
 
 
-
 
NC_011145  AnaeK_4317  translation initiation factor, aIF-2BI family  29.86 
 
 
339 aa  123  6e-27  Anaeromyxobacter sp. K  Bacteria  normal  n/a   
 
 
-
 
NC_013173  Dbac_0191  translation initiation factor, aIF-2BI family  30.79 
 
 
348 aa  122  6e-27  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  n/a   
 
 
-
 
NC_009767  Rcas_0156  eIF-2B alpha/beta/delta-related uncharacterized protein  28.69 
 
 
354 aa  122  6e-27  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.232234  normal 
 
 
-
 
NC_011071  Smal_2579  methylthioribose-1-phosphate isomerase  29.64 
 
 
354 aa  122  9.999999999999999e-27  Stenotrophomonas maltophilia R551-3  Bacteria  normal  normal 
 
 
-
 
NC_009634  Mevan_0927  aIF-2BI family translation initiation factor  32.56 
 
 
323 aa  121  1.9999999999999998e-26  Methanococcus vannielii SB  Archaea  normal  n/a   
 
 
-
 
NC_011761  AFE_0893  translation initiation factor, putative, aIF-2BI family  29.18 
 
 
350 aa  120  3e-26  Acidithiobacillus ferrooxidans ATCC 23270  Bacteria  normal  0.592347  n/a   
 
 
-
 
NC_008463  PA14_23250  methylthioribose-1-phosphate isomerase  27.53 
 
 
358 aa  120  3e-26  Pseudomonas aeruginosa UCBPP-PA14  Bacteria  normal  hitchhiker  0.0078361 
 
 
-
 
NC_011206  Lferr_1015  translation initiation factor, aIF-2BI family  29.18 
 
 
350 aa  120  3e-26  Acidithiobacillus ferrooxidans ATCC 53993  Bacteria  normal  0.253315  unclonable  0.0000000000388932 
 
 
-
 
NC_006274  BCZK3789  methylthioribose-1-phosphate isomerase  30.81 
 
 
351 aa  120  3.9999999999999996e-26  Bacillus cereus E33L  Bacteria  normal  0.700016  n/a   
 
 
-
 
NC_007644  Moth_0703  translation initiation factor 2B subunit I  28.86 
 
 
351 aa  120  3.9999999999999996e-26  Moorella thermoacetica ATCC 39073  Bacteria  normal  hitchhiker  0.000787843 
 
 
-
 
NC_014148  Plim_1381  translation initiation factor, aIF-2BI family  28.33 
 
 
362 aa  120  4.9999999999999996e-26  Planctomyces limnophilus DSM 3776  Bacteria  normal  0.705402  n/a   
 
 
-
 
NC_013411  GYMC61_1741  methylthioribose-1-phosphate isomerase  31.58 
 
 
355 aa  120  4.9999999999999996e-26  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_009656  PSPA7_1960  methylthioribose-1-phosphate isomerase  27.25 
 
 
358 aa  120  4.9999999999999996e-26  Pseudomonas aeruginosa PA7  Bacteria  normal  n/a   
 
 
-
 
NC_011884  Cyan7425_3816  methylthioribose-1-phosphate isomerase  29.97 
 
 
350 aa  119  6e-26  Cyanothece sp. PCC 7425  Bacteria  normal  normal  0.732544 
 
 
-
 
NC_008312  Tery_2078  methylthioribose-1-phosphate isomerase  28.45 
 
 
353 aa  119  7.999999999999999e-26  Trichodesmium erythraeum IMS101  Bacteria  normal  normal  0.424406 
 
 
-
 
NC_009051  Memar_1694  aIF-2BI family translation initiation factor  29.23 
 
 
353 aa  119  7.999999999999999e-26  Methanoculleus marisnigri JR1  Archaea  normal  n/a   
 
 
-
 
NC_011658  BCAH187_A4159  methylthioribose-1-phosphate isomerase  30.52 
 
 
351 aa  119  7.999999999999999e-26  Bacillus cereus AH187  Bacteria  normal  0.109098  n/a   
 
 
-
 
NC_003909  BCE_4098  methylthioribose-1-phosphate isomerase  30.52 
 
 
351 aa  119  9.999999999999999e-26  Bacillus cereus ATCC 10987  Bacteria  normal  0.463174  n/a   
 
 
-
 
NC_005945  BAS3942  methylthioribose-1-phosphate isomerase  30.81 
 
 
351 aa  118  9.999999999999999e-26  Bacillus anthracis str. Sterne  Bacteria  normal  n/a   
 
 
-
 
NC_005957  BT9727_3774  methylthioribose-1-phosphate isomerase  30.9 
 
 
351 aa  118  9.999999999999999e-26  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  n/a   
 
 
-
 
NC_007530  GBAA_4251  methylthioribose-1-phosphate isomerase  30.81 
 
 
351 aa  118  9.999999999999999e-26  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  n/a   
 
 
-
 
NC_009954  Cmaq_0396  translation initiation factor IF-2B subunit alpha  29.97 
 
 
370 aa  119  9.999999999999999e-26  Caldivirga maquilingensis IC-167  Archaea  normal  0.359627  normal 
 
 
-
 
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