More than 300 homologs were found in PanDaTox collection
for query gene Amuc_0042 on replicon NC_010655
Organism: Akkermansia muciniphila ATCC BAA-835



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_010655  Amuc_0042  protein-(glutamine-N5) methyltransferase, release factor-specific  100 
 
 
301 aa  615  1e-175  Akkermansia muciniphila ATCC BAA-835  Bacteria  normal  normal  0.24008 
 
 
-
 
NC_011145  AnaeK_0393  protein-(glutamine-N5) methyltransferase, release factor-specific  38.51 
 
 
286 aa  178  9e-44  Anaeromyxobacter sp. K  Bacteria  normal  n/a   
 
 
-
 
NC_009675  Anae109_4214  HemK family modification methylase  38.18 
 
 
285 aa  175  8e-43  Anaeromyxobacter sp. Fw109-5  Bacteria  normal  0.603488  normal 
 
 
-
 
NC_011891  A2cp1_0395  modification methylase, HemK family  37.84 
 
 
286 aa  175  8e-43  Anaeromyxobacter dehalogenans 2CP-1  Bacteria  normal  n/a   
 
 
-
 
NC_007760  Adeh_0365  HemK family modification methylase  38.38 
 
 
286 aa  171  1e-41  Anaeromyxobacter dehalogenans 2CP-C  Bacteria  normal  0.850958  n/a   
 
 
-
 
NC_008554  Sfum_1714  HemK family modification methylase  38.26 
 
 
288 aa  165  9e-40  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  0.69784  normal  0.935147 
 
 
-
 
NC_010571  Oter_3497  protein-(glutamine-N5) methyltransferase, release factor-specific  38.83 
 
 
284 aa  163  3e-39  Opitutus terrae PB90-1  Bacteria  normal  0.531289  normal  0.236776 
 
 
-
 
NC_002939  GSU3103  HemK family modification methylase  36.24 
 
 
284 aa  162  9e-39  Geobacter sulfurreducens PCA  Bacteria  normal  n/a   
 
 
-
 
NC_011899  Hore_17960  modification methylase, HemK family  36.75 
 
 
285 aa  161  1e-38  Halothermothrix orenii H 168  Bacteria  hitchhiker  0.0000000857444  n/a   
 
 
-
 
NC_011662  Tmz1t_1425  modification methylase, HemK family  37.2 
 
 
289 aa  160  2e-38  Thauera sp. MZ1T  Bacteria  normal  0.949307  n/a   
 
 
-
 
NC_007498  Pcar_2691  putative protoporphyrinogen oxidase  38.67 
 
 
287 aa  159  7e-38  Pelobacter carbinolicus DSM 2380  Bacteria  normal  0.0268628  n/a   
 
 
-
 
NC_009483  Gura_4060  HemK family modification methylase  35.47 
 
 
284 aa  159  8e-38  Geobacter uraniireducens Rf4  Bacteria  normal  0.867838  n/a   
 
 
-
 
NC_013440  Hoch_2497  protein-(glutamine-N5) methyltransferase, release factor-specific  38.73 
 
 
288 aa  156  3e-37  Haliangium ochraceum DSM 14365  Bacteria  normal  0.327963  normal  0.48077 
 
 
-
 
NC_008009  Acid345_4471  HemK family modification methylase  35.86 
 
 
280 aa  156  4e-37  Candidatus Koribacter versatilis Ellin345  Bacteria  normal  0.44182  normal 
 
 
-
 
NC_013517  Sterm_2448  modification methylase, HemK family  35.43 
 
 
361 aa  154  2e-36  Sebaldella termitidis ATCC 33386  Bacteria  normal  n/a   
 
 
-
 
NC_008346  Swol_2396  peptide release factor-glutamine N5-methyltransferase  37.29 
 
 
282 aa  153  2.9999999999999998e-36  Syntrophomonas wolfei subsp. wolfei str. Goettingen  Bacteria  hitchhiker  0.0000357803  n/a   
 
 
-
 
NC_007517  Gmet_0381  modification methylase HemK  34.8 
 
 
284 aa  150  3e-35  Geobacter metallireducens GS-15  Bacteria  normal  normal 
 
 
-
 
NC_010814  Glov_1030  protein-(glutamine-N5) methyltransferase, release factor-specific  33.56 
 
 
286 aa  149  7e-35  Geobacter lovleyi SZ  Bacteria  normal  0.864294  n/a   
 
 
-
 
NC_010644  Emin_1094  protein-(glutamine-N5) methyltransferase, release factor-specific  32.57 
 
 
277 aa  147  1.0000000000000001e-34  Elusimicrobium minutum Pei191  Bacteria  normal  0.747327  normal 
 
 
-
 
NC_009012  Cthe_2428  HemK family modification methylase  36.13 
 
 
302 aa  146  3e-34  Clostridium thermocellum ATCC 27405  Bacteria  normal  0.185206  n/a   
 
 
-
 
NC_007298  Daro_3684  modification methylase HemK  33.89 
 
 
270 aa  146  5e-34  Dechloromonas aromatica RCB  Bacteria  normal  normal 
 
 
-
 
NC_013171  Apre_0752  modification methylase, HemK family  33.09 
 
 
262 aa  145  7.0000000000000006e-34  Anaerococcus prevotii DSM 20548  Bacteria  decreased coverage  0.0000000141124  n/a   
 
 
-
 
NC_007947  Mfla_2476  HemK family modification methylase  36.49 
 
 
284 aa  145  7.0000000000000006e-34  Methylobacillus flagellatus KT  Bacteria  normal  normal 
 
 
-
 
NC_011772  BCG9842_B5501  protein-(glutamine-N5) methyltransferase, release factor-specific  33 
 
 
283 aa  145  7.0000000000000006e-34  Bacillus cereus G9842  Bacteria  hitchhiker  0.0000000174977  unclonable  6.52131e-26 
 
 
-
 
NC_008609  Ppro_3005  HemK family modification methylase  35.92 
 
 
288 aa  145  7.0000000000000006e-34  Pelobacter propionicus DSM 2379  Bacteria  normal  n/a   
 
 
-
 
NC_008639  Cpha266_1875  HemK family modification methylase  36.25 
 
 
301 aa  145  9e-34  Chlorobium phaeobacteroides DSM 266  Bacteria  normal  0.210428  n/a   
 
 
-
 
NC_013501  Rmar_1808  modification methylase, HemK family  34.32 
 
 
304 aa  145  1e-33  Rhodothermus marinus DSM 4252  Bacteria  normal  n/a   
 
 
-
 
NC_013411  GYMC61_3434  protein-(glutamine-N5) methyltransferase, release factor-specific  35.16 
 
 
293 aa  143  4e-33  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_010320  Teth514_0093  HemK family modification methylase  34.58 
 
 
279 aa  142  6e-33  Thermoanaerobacter sp. X514  Bacteria  normal  0.165478  n/a   
 
 
-
 
NC_011059  Paes_1585  protein-(glutamine-N5) methyltransferase, release factor-specific  35.1 
 
 
297 aa  142  6e-33  Prosthecochloris aestuarii DSM 271  Bacteria  normal  0.123528  normal  0.907026 
 
 
-
 
NC_011725  BCB4264_A5451  protein-(glutamine-N5) methyltransferase, release factor-specific  32.34 
 
 
283 aa  142  8e-33  Bacillus cereus B4264  Bacteria  hitchhiker  0.00030744  n/a   
 
 
-
 
NC_011060  Ppha_1085  protein-(glutamine-N5) methyltransferase, release factor-specific  35.67 
 
 
299 aa  141  9.999999999999999e-33  Pelodictyon phaeoclathratiforme BU-1  Bacteria  hitchhiker  0.00355762  n/a   
 
 
-
 
NC_009943  Dole_0473  HemK family modification methylase  33.88 
 
 
297 aa  140  3e-32  Desulfococcus oleovorans Hxd3  Bacteria  unclonable  0.000000000302756  n/a   
 
 
-
 
NC_013456  VEA_004202  Polypeptide chain release factor methylase  33.77 
 
 
284 aa  139  4.999999999999999e-32  Vibrio sp. Ex25  Bacteria  normal  0.19334  n/a   
 
 
-
 
NC_007512  Plut_1490  modification methylase HemK  37 
 
 
296 aa  139  7e-32  Chlorobium luteolum DSM 273  Bacteria  normal  normal 
 
 
-
 
NC_009457  VC0395_A1755  hemK protein  34.33 
 
 
286 aa  138  8.999999999999999e-32  Vibrio cholerae O395  Bacteria  hitchhiker  0.0000000114264  n/a   
 
 
-
 
NC_005957  BT9727_5012  HemK family modification methylase  31.68 
 
 
283 aa  138  1e-31  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  hitchhiker  0.000084912  n/a   
 
 
-
 
NC_012793  GWCH70_3321  modification methylase, HemK family  34.2 
 
 
288 aa  138  1e-31  Geobacillus sp. WCH70  Bacteria  hitchhiker  0.000192098  n/a   
 
 
-
 
NC_009674  Bcer98_3849  HemK family modification methylase  32.34 
 
 
283 aa  138  1e-31  Bacillus cytotoxicus NVH 391-98  Bacteria  hitchhiker  0.00000350241  n/a   
 
 
-
 
NC_005945  BAS5177  HemK family modification methylase  31.68 
 
 
283 aa  137  2e-31  Bacillus anthracis str. Sterne  Bacteria  normal  0.825959  n/a   
 
 
-
 
NC_007530  GBAA_5571  HemK family modification methylase  31.68 
 
 
283 aa  137  2e-31  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  hitchhiker  0.0023749  n/a   
 
 
-
 
NC_010803  Clim_1694  protein-(glutamine-N5) methyltransferase, release factor-specific  36.48 
 
 
296 aa  137  2e-31  Chlorobium limicola DSM 245  Bacteria  normal  0.886603  n/a   
 
 
-
 
NC_011773  BCAH820_5420  protein-(glutamine-N5) methyltransferase, release factor-specific  31.68 
 
 
283 aa  137  2e-31  Bacillus cereus AH820  Bacteria  n/a    unclonable  9.97899e-62 
 
 
-
 
NC_011658  BCAH187_A5506  protein-(glutamine-N5) methyltransferase, release factor-specific  31.68 
 
 
283 aa  137  3.0000000000000003e-31  Bacillus cereus AH187  Bacteria  hitchhiker  0.000000117496  n/a   
 
 
-
 
NC_007514  Cag_1425  modification methylase HemK  34 
 
 
297 aa  137  3.0000000000000003e-31  Chlorobium chlorochromatii CaD3  Bacteria  normal  n/a   
 
 
-
 
NC_003909  BCE_5455  HemK family modification methylase  31.35 
 
 
283 aa  136  4e-31  Bacillus cereus ATCC 10987  Bacteria  hitchhiker  0.00426366  n/a   
 
 
-
 
NC_011071  Smal_0690  protein-(glutamine-N5) methyltransferase, release factor-specific  32.87 
 
 
285 aa  136  5e-31  Stenotrophomonas maltophilia R551-3  Bacteria  normal  normal  0.38901 
 
 
-
 
NC_013515  Smon_0616  modification methylase, HemK family  28.16 
 
 
359 aa  136  5e-31  Streptobacillus moniliformis DSM 12112  Bacteria  n/a    n/a   
 
 
-
 
NC_008390  Bamb_0413  HemK family modification methylase  36.3 
 
 
280 aa  136  5e-31  Burkholderia ambifaria AMMD  Bacteria  normal  n/a   
 
 
-
 
NC_009455  DehaBAV1_1021  HemK family modification methylase  33.9 
 
 
277 aa  135  6.0000000000000005e-31  Dehalococcoides sp. BAV1  Bacteria  normal  n/a   
 
 
-
 
NC_006274  BCZK5028  HemK family modification methylase  31.68 
 
 
283 aa  135  6.0000000000000005e-31  Bacillus cereus E33L  Bacteria  normal  0.497663  n/a   
 
 
-
 
NC_008528  OEOE_1581  methylase of polypeptide chain release factor  33.81 
 
 
275 aa  135  8e-31  Oenococcus oeni PSU-1  Bacteria  normal  n/a   
 
 
-
 
NC_010508  Bcenmc03_0481  protein-(glutamine-N5) methyltransferase, release factor-specific  36.36 
 
 
280 aa  134  9.999999999999999e-31  Burkholderia cenocepacia MC0-3  Bacteria  normal  normal  0.589534 
 
 
-
 
NC_008751  Dvul_0450  HemK family modification methylase  32.03 
 
 
295 aa  135  9.999999999999999e-31  Desulfovibrio vulgaris DP4  Bacteria  normal  normal 
 
 
-
 
NC_010084  Bmul_2889  protein-(glutamine-N5) methyltransferase, release factor-specific  35.34 
 
 
280 aa  135  9.999999999999999e-31  Burkholderia multivorans ATCC 17616  Bacteria  normal  normal  0.479944 
 
 
-
 
NC_009253  Dred_3169  HemK family modification methylase  34.55 
 
 
289 aa  135  9.999999999999999e-31  Desulfotomaculum reducens MI-1  Bacteria  normal  0.0174624  n/a   
 
 
-
 
NC_008025  Dgeo_0068  HemK family modification methylase  34.34 
 
 
283 aa  134  1.9999999999999998e-30  Deinococcus geothermalis DSM 11300  Bacteria  normal  normal 
 
 
-
 
NC_013223  Dret_2082  protein-(glutamine-N5) methyltransferase, release factor-specific  34.21 
 
 
300 aa  134  1.9999999999999998e-30  Desulfohalobium retbaense DSM 5692  Bacteria  hitchhiker  0.0000794612  normal 
 
 
-
 
NC_008781  Pnap_0774  HemK family modification methylase  36.29 
 
 
283 aa  133  3e-30  Polaromonas naphthalenivorans CJ2  Bacteria  normal  normal  0.0850729 
 
 
-
 
NC_008060  Bcen_2596  HemK family modification methylase  36.36 
 
 
280 aa  133  3e-30  Burkholderia cenocepacia AU 1054  Bacteria  normal  0.944902  n/a   
 
 
-
 
NC_008542  Bcen2424_0509  HemK family modification methylase  36.36 
 
 
280 aa  133  3e-30  Burkholderia cenocepacia HI2424  Bacteria  normal  0.0843228  n/a   
 
 
-
 
NC_010551  BamMC406_0439  protein-(glutamine-N5) methyltransferase, release factor-specific  35.59 
 
 
280 aa  133  3.9999999999999996e-30  Burkholderia ambifaria MC40-6  Bacteria  normal  normal  0.490288 
 
 
-
 
NC_010831  Cphamn1_0851  protein-(glutamine-N5) methyltransferase, release factor-specific  34.11 
 
 
297 aa  133  3.9999999999999996e-30  Chlorobium phaeobacteroides BS1  Bacteria  normal  0.0252199  normal 
 
 
-
 
NC_011830  Dhaf_4832  modification methylase, HemK family  31.17 
 
 
285 aa  132  5e-30  Desulfitobacterium hafniense DCB-2  Bacteria  hitchhiker  0.0000233725  n/a   
 
 
-
 
NC_010511  M446_4749  protein-(glutamine-N5) methyltransferase, release factor-specific  35.22 
 
 
295 aa  131  1.0000000000000001e-29  Methylobacterium sp. 4-46  Bacteria  normal  normal 
 
 
-
 
NC_010498  EcSMS35_1930  N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase  31.58 
 
 
277 aa  131  1.0000000000000001e-29  Escherichia coli SMS-3-5  Bacteria  hitchhiker  0.00345869  normal  0.0875835 
 
 
-
 
NC_010622  Bphy_2722  protein-(glutamine-N5) methyltransferase, release factor-specific  32.86 
 
 
283 aa  131  2.0000000000000002e-29  Burkholderia phymatum STM815  Bacteria  normal  normal 
 
 
-
 
NC_009783  VIBHAR_01251  hypothetical protein  32.45 
 
 
285 aa  131  2.0000000000000002e-29  Vibrio harveyi ATCC BAA-1116  Bacteria  n/a    n/a   
 
 
-
 
NC_010730  SYO3AOP1_0166  protein-(glutamine-N5) methyltransferase, release factor-specific  33.58 
 
 
291 aa  131  2.0000000000000002e-29  Sulfurihydrogenibium sp. YO3AOP1  Bacteria  normal  n/a   
 
 
-
 
NC_010184  BcerKBAB4_5126  HemK family modification methylase  32.34 
 
 
283 aa  130  2.0000000000000002e-29  Bacillus weihenstephanensis KBAB4  Bacteria  normal  0.0481456  n/a   
 
 
-
 
NC_013216  Dtox_0065  modification methylase, HemK family  35.33 
 
 
289 aa  130  2.0000000000000002e-29  Desulfotomaculum acetoxidans DSM 771  Bacteria  hitchhiker  0.0000000787039  hitchhiker  0.00284292 
 
 
-
 
NC_007644  Moth_2396  HemK family modification methylase  34.43 
 
 
283 aa  130  3e-29  Moorella thermoacetica ATCC 39073  Bacteria  normal  normal  0.299117 
 
 
-
 
NC_008527  LACR_0614  methylase of polypeptide chain release factor  35.58 
 
 
271 aa  130  3e-29  Lactococcus lactis subsp. cremoris SK11  Bacteria  normal  n/a   
 
 
-
 
NC_008576  Mmc1_3505  HemK family modification methylase  32.46 
 
 
289 aa  130  3e-29  Magnetococcus sp. MC-1  Bacteria  normal  0.216122  normal 
 
 
-
 
NC_004116  SAG1076  HemK family modification methylase  31.8 
 
 
276 aa  129  6e-29  Streptococcus agalactiae 2603V/R  Bacteria  normal  0.260993  n/a   
 
 
-
 
NC_014148  Plim_3974  modification methylase, HemK family  30.23 
 
 
307 aa  129  6e-29  Planctomyces limnophilus DSM 3776  Bacteria  normal  n/a   
 
 
-
 
NC_007404  Tbd_2494  modification methylase HemK  35.79 
 
 
287 aa  129  6e-29  Thiobacillus denitrificans ATCC 25259  Bacteria  normal  0.977942  normal 
 
 
-
 
NC_008700  Sama_2565  hemK family protein  34.55 
 
 
285 aa  129  6e-29  Shewanella amazonensis SB2B  Bacteria  normal  0.264482  normal  0.189465 
 
 
-
 
NC_002936  DET1211  HemK family modification methylase  34.24 
 
 
277 aa  129  8.000000000000001e-29  Dehalococcoides ethenogenes 195  Bacteria  normal  n/a   
 
 
-
 
NC_007510  Bcep18194_A3596  modification methylase HemK  35.51 
 
 
280 aa  129  8.000000000000001e-29  Burkholderia sp. 383  Bacteria  normal  normal  0.900559 
 
 
-
 
NC_014150  Bmur_1660  protein-(glutamine-N5) methyltransferase, release factor-specific  31.16 
 
 
287 aa  129  8.000000000000001e-29  Brachyspira murdochii DSM 12563  Bacteria  normal  n/a   
 
 
-
 
NC_008531  LEUM_1783  methylase of polypeptide chain release factor  34.85 
 
 
330 aa  129  8.000000000000001e-29  Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293  Bacteria  normal  n/a   
 
 
-
 
NC_004578  PSPTO_1110  hemK protein  32.16 
 
 
277 aa  128  9.000000000000001e-29  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  n/a   
 
 
-
 
NC_011146  Gbem_3708  protein-(glutamine-N5) methyltransferase, release factor-specific  35.46 
 
 
285 aa  128  1.0000000000000001e-28  Geobacter bemidjiensis Bem  Bacteria  normal  0.432001  n/a   
 
 
-
 
NC_013385  Adeg_0064  protein-(glutamine-N5) methyltransferase, release factor-specific  34.8 
 
 
287 aa  128  1.0000000000000001e-28  Ammonifex degensii KC4  Bacteria  hitchhiker  0.000000292458  n/a   
 
 
-
 
CP001637  EcDH1_2435  modification methylase, HemK family  31.23 
 
 
277 aa  127  2.0000000000000002e-28  Escherichia coli DH1  Bacteria  hitchhiker  0.000273113  n/a   
 
 
-
 
NC_009800  EcHS_A1317  N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase  31.23 
 
 
277 aa  127  2.0000000000000002e-28  Escherichia coli HS  Bacteria  hitchhiker  0.000000106766  n/a   
 
 
-
 
NC_007519  Dde_2985  HemK family modification methylase  31.51 
 
 
297 aa  127  2.0000000000000002e-28  Desulfovibrio desulfuricans subsp. desulfuricans str. G20  Bacteria  normal  n/a   
 
 
-
 
NC_010468  EcolC_2414  N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase  31.23 
 
 
277 aa  127  2.0000000000000002e-28  Escherichia coli ATCC 8739  Bacteria  normal  0.0911991  hitchhiker  0.0000261137 
 
 
-
 
NC_009436  Ent638_2336  N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase  33.09 
 
 
276 aa  127  2.0000000000000002e-28  Enterobacter sp. 638  Bacteria  normal  normal 
 
 
-
 
NC_010658  SbBS512_E1376  N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase  31.23 
 
 
277 aa  127  2.0000000000000002e-28  Shigella boydii CDC 3083-94  Bacteria  hitchhiker  0.000091189  n/a   
 
 
-
 
NC_009513  Lreu_0453  HemK family modification methylase  32.2 
 
 
288 aa  127  2.0000000000000002e-28  Lactobacillus reuteri DSM 20016  Bacteria  normal  n/a   
 
 
-
 
NC_008345  Sfri_0724  modification methylase, HemK family protein  29.24 
 
 
284 aa  127  2.0000000000000002e-28  Shewanella frigidimarina NCIMB 400  Bacteria  normal  n/a   
 
 
-
 
CP001509  ECD_01187  N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase  31.23 
 
 
277 aa  126  4.0000000000000003e-28  Escherichia coli BL21(DE3)  Bacteria  normal  0.368391  n/a   
 
 
-
 
NC_011898  Ccel_3373  modification methylase, HemK family  34.77 
 
 
285 aa  126  4.0000000000000003e-28  Clostridium cellulolyticum H10  Bacteria  normal  0.359412  n/a   
 
 
-
 
NC_007908  Rfer_1279  HemK family modification methylase  33.44 
 
 
280 aa  126  4.0000000000000003e-28  Rhodoferax ferrireducens T118  Bacteria  normal  n/a   
 
 
-
 
NC_009524  PsycPRwf_1772  HemK family modification methylase  30.1 
 
 
314 aa  126  4.0000000000000003e-28  Psychrobacter sp. PRwf-1  Bacteria  normal  normal 
 
 
-
 
NC_012892  B21_01197  hypothetical protein  31.23 
 
 
277 aa  126  4.0000000000000003e-28  Escherichia coli BL21  Bacteria  normal  0.337876  n/a   
 
 
-
 
NC_011353  ECH74115_1693  N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase  31.23 
 
 
277 aa  126  5e-28  Escherichia coli O157:H7 str. EC4115  Bacteria  hitchhiker  0.0062068  normal 
 
 
-
 
NC_012918  GM21_3803  modification methylase, HemK family  34.75 
 
 
285 aa  125  6e-28  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
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