More than 300 homologs were found in PanDaTox collection
for query gene Jann_1147 on replicon NC_007802
Organism: Jannaschia sp. CCS1



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_004310  BR0018  biotin carboxylase  59.91 
 
 
673 aa  663    Brucella suis 1330  Bacteria  normal  n/a   
 
 
-
 
NC_008687  Pden_3639  carbamoyl-phosphate synthase L chain, ATP-binding  69.41 
 
 
642 aa  805    Paracoccus denitrificans PD1222  Bacteria  normal  normal 
 
 
-
 
NC_009049  Rsph17029_1171  carbamoyl-phosphate synthase L chain, ATP-binding  66.93 
 
 
646 aa  778    Rhodobacter sphaeroides ATCC 17029  Bacteria  normal  0.42621  normal 
 
 
-
 
NC_007493  RSP_2509  3-methylcrotonoyl-CoA carboxylase, alpha subunit  66.77 
 
 
646 aa  776    Rhodobacter sphaeroides 2.4.1  Bacteria  normal  0.509464  n/a   
 
 
-
 
NC_007802  Jann_1147  3-methylcrotonoyl-CoA carboxylase, alpha subunit  100 
 
 
667 aa  1333    Jannaschia sp. CCS1  Bacteria  normal  normal  0.221564 
 
 
-
 
NC_009667  Oant_0039  carbamoyl-phosphate synthase L chain ATP-binding  60.82 
 
 
655 aa  664    Ochrobactrum anthropi ATCC 49188  Bacteria  normal  0.540073  n/a   
 
 
-
 
NC_009952  Dshi_1301  carbamoyl-phosphate synthase L chain ATP-binding  73.56 
 
 
661 aa  811    Dinoroseobacter shibae DFL 12  Bacteria  normal  0.206291  normal  0.197906 
 
 
-
 
NC_008044  TM1040_0738  3-methylcrotonoyl-CoA carboxylase, alpha subunit  69.35 
 
 
645 aa  833    Ruegeria sp. TM1040  Bacteria  normal  0.623779  normal 
 
 
-
 
NC_009505  BOV_0015  biotin carboxylase  59.91 
 
 
673 aa  665    Brucella ovis ATCC 25840  Bacteria  normal  n/a   
 
 
-
 
NC_009428  Rsph17025_2010  carbamoyl-phosphate synthase L chain, ATP-binding  66.98 
 
 
646 aa  765    Rhodobacter sphaeroides ATCC 17025  Bacteria  normal  normal 
 
 
-
 
NC_009620  Smed_4535  carbamoyl-phosphate synthase L chain ATP-binding  56.63 
 
 
662 aa  630  1e-179  Sinorhizobium medicae WSM419  Bacteria  normal  normal 
 
 
-
 
NC_009719  Plav_2788  carbamoyl-phosphate synthase L chain ATP-binding  54.88 
 
 
673 aa  609  1e-173  Parvibaculum lavamentivorans DS-1  Bacteria  normal  0.683073  normal  0.298513 
 
 
-
 
NC_010511  M446_2316  carbamoyl-phosphate synthase L chain ATP-binding  57.25 
 
 
662 aa  601  1e-170  Methylobacterium sp. 4-46  Bacteria  normal  0.0459588  normal  0.101585 
 
 
-
 
NC_007969  Pcryo_0342  carbamoyl-phosphate synthase L chain, ATP-binding  50.5 
 
 
704 aa  602  1e-170  Psychrobacter cryohalolentis K5  Bacteria  normal  normal 
 
 
-
 
NC_007204  Psyc_0311  3-methylcrotonoyl-CoA carboxylase, alpha subunit  50.07 
 
 
706 aa  596  1e-169  Psychrobacter arcticus 273-4  Bacteria  normal  normal 
 
 
-
 
NC_011071  Smal_0196  Carbamoyl-phosphate synthase L chain ATP-binding  55.26 
 
 
660 aa  594  1e-168  Stenotrophomonas maltophilia R551-3  Bacteria  normal  0.469913  normal 
 
 
-
 
NC_007948  Bpro_4157  3-methylcrotonoyl-CoA carboxylase, alpha subunit  53.83 
 
 
663 aa  594  1e-168  Polaromonas sp. JS666  Bacteria  normal  0.825758  normal 
 
 
-
 
NC_008781  Pnap_0475  carbamoyl-phosphate synthase L chain, ATP-binding  52.62 
 
 
670 aa  586  1e-166  Polaromonas naphthalenivorans CJ2  Bacteria  normal  normal 
 
 
-
 
NC_008752  Aave_4351  3-methylcrotonoyl-CoA carboxylase, alpha subunit  55.74 
 
 
677 aa  585  1.0000000000000001e-165  Acidovorax citrulli AAC00-1  Bacteria  normal  normal 
 
 
-
 
NC_009720  Xaut_1855  carbamoyl-phosphate synthase L chain ATP-binding  52.8 
 
 
666 aa  578  1e-164  Xanthobacter autotrophicus Py2  Bacteria  normal  0.181486  normal 
 
 
-
 
NC_008782  Ajs_3759  3-methylcrotonoyl-CoA carboxylase, alpha subunit  53.3 
 
 
672 aa  580  1e-164  Acidovorax sp. JS42  Bacteria  normal  normal  0.746239 
 
 
-
 
NC_011992  Dtpsy_3040  Carbamoyl-phosphate synthase L chain ATP-binding  53.3 
 
 
672 aa  580  1e-164  Acidovorax ebreus TPSY  Bacteria  normal  0.233889  n/a   
 
 
-
 
NC_008048  Sala_1533  carbamoyl-phosphate synthase L chain, ATP-binding  55.85 
 
 
612 aa  580  1e-164  Sphingopyxis alaskensis RB2256  Bacteria  normal  0.385954  normal 
 
 
-
 
NC_008254  Meso_0918  3-methylcrotonoyl-CoA carboxylase, alpha subunit  57.42 
 
 
650 aa  581  1e-164  Chelativorans sp. BNC1  Bacteria  normal  n/a   
 
 
-
 
NC_010623  Bphy_3559  carbamoyl-phosphate synthase L chain ATP-binding  51.84 
 
 
670 aa  578  1.0000000000000001e-163  Burkholderia phymatum STM815  Bacteria  normal  normal  0.733851 
 
 
-
 
NC_007517  Gmet_3292  3-methylcrotonoyl-CoA carboxylase, alpha subunit  52.52 
 
 
668 aa  575  1.0000000000000001e-163  Geobacter metallireducens GS-15  Bacteria  normal  normal 
 
 
-
 
NC_007347  Reut_A1463  3-methylcrotonoyl-CoA carboxylase, alpha subunit  53.13 
 
 
674 aa  574  1.0000000000000001e-162  Ralstonia eutropha JMP134  Bacteria  normal  n/a   
 
 
-
 
NC_011981  Avi_7691  acetyl-CoA carboxylase biotin carboxylase  52.63 
 
 
662 aa  570  1e-161  Agrobacterium vitis S4  Bacteria  normal  0.817206  n/a   
 
 
-
 
NC_010002  Daci_5970  carbamoyl-phosphate synthase L chain ATP-binding  54.72 
 
 
672 aa  571  1e-161  Delftia acidovorans SPH-1  Bacteria  normal  normal 
 
 
-
 
NC_003910  CPS_1600  methylcrotonyl-CoA carboxylase, alpha subunit  47.45 
 
 
681 aa  560  1e-158  Colwellia psychrerythraea 34H  Bacteria  normal  n/a   
 
 
-
 
NC_010338  Caul_3151  carbamoyl-phosphate synthase L chain ATP-binding  53.32 
 
 
657 aa  559  1e-158  Caulobacter sp. K31  Bacteria  normal  normal  0.111688 
 
 
-
 
NC_010676  Bphyt_4689  Carbamoyl-phosphate synthase L chain ATP-binding  50.29 
 
 
692 aa  561  1e-158  Burkholderia phytofirmans PsJN  Bacteria  normal  normal 
 
 
-
 
NC_008825  Mpe_A3356  3-methylcrotonoyl-CoA carboxylase, alpha subunit  52.42 
 
 
672 aa  560  1e-158  Methylibium petroleiphilum PM1  Bacteria  normal  normal  0.782884 
 
 
-
 
NC_007908  Rfer_3830  carbamoyl-phosphate synthase L chain, ATP-binding  52.79 
 
 
674 aa  561  1e-158  Rhodoferax ferrireducens T118  Bacteria  normal  n/a   
 
 
-
 
NC_008740  Maqu_2125  carbamoyl-phosphate synthase L chain, ATP-binding  51.49 
 
 
662 aa  556  1e-157  Marinobacter aquaeolei VT8  Bacteria  normal  n/a   
 
 
-
 
NC_010524  Lcho_2116  carbamoyl-phosphate synthase L chain ATP-binding  51.56 
 
 
692 aa  558  1e-157  Leptothrix cholodnii SP-6  Bacteria  n/a    normal  0.278717 
 
 
-
 
NC_010717  PXO_03803  biotin carboxylase  53.45 
 
 
675 aa  557  1e-157  Xanthomonas oryzae pv. oryzae PXO99A  Bacteria  normal  n/a   
 
 
-
 
NC_007973  Rmet_0608  3-methylcrotonoyl-CoA carboxylase, subunit alpha  52.01 
 
 
679 aa  557  1e-157  Cupriavidus metallidurans CH34  Bacteria  decreased coverage  0.00695575  normal  0.371744 
 
 
-
 
NC_003295  RSc0265  acyl-CoA carboxylase subunit alpha  52.42 
 
 
712 aa  553  1e-156  Ralstonia solanacearum GMI1000  Bacteria  normal  normal 
 
 
-
 
NC_010086  Bmul_3469  carbamoyl-phosphate synthase L chain ATP-binding  52.02 
 
 
670 aa  553  1e-156  Burkholderia multivorans ATCC 17616  Bacteria  normal  normal 
 
 
-
 
NC_007298  Daro_0089  3-methylcrotonoyl-CoA carboxylase, alpha subunit  51.42 
 
 
666 aa  553  1e-156  Dechloromonas aromatica RCB  Bacteria  normal  normal 
 
 
-
 
NC_007347  Reut_A0151  3-methylcrotonoyl-CoA carboxylase, alpha subunit  52.21 
 
 
674 aa  552  1e-156  Ralstonia eutropha JMP134  Bacteria  normal  n/a   
 
 
-
 
NC_007952  Bxe_B0963  3-methylcrotonoyl-CoA carboxylase, alpha subunit  51.24 
 
 
679 aa  552  1e-156  Burkholderia xenovorans LB400  Bacteria  normal  normal  0.5845 
 
 
-
 
NC_012791  Vapar_4719  Carbamoyl-phosphate synthase L chain ATP-binding  53.12 
 
 
667 aa  555  1e-156  Variovorax paradoxus S110  Bacteria  normal  n/a   
 
 
-
 
NC_008391  Bamb_4585  carbamoyl-phosphate synthase L chain, ATP-binding  52.75 
 
 
666 aa  555  1e-156  Burkholderia ambifaria AMMD  Bacteria  normal  normal  0.747689 
 
 
-
 
NC_008347  Mmar10_1727  carbamoyl-phosphate synthase L chain, ATP-binding  52.37 
 
 
667 aa  553  1e-156  Maricaulis maris MCS10  Bacteria  normal  0.807685  normal  0.290764 
 
 
-
 
NC_012854  Rleg_6512  Carbamoyl-phosphate synthase L chain ATP-binding  50.46 
 
 
621 aa  549  1e-155  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  normal  0.0609774 
 
 
-
 
NC_011368  Rleg2_4376  Carbamoyl-phosphate synthase L chain ATP-binding  52.37 
 
 
621 aa  548  1e-155  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  0.672577  normal 
 
 
-
 
NC_009524  PsycPRwf_2064  carbamoyl-phosphate synthase L chain, ATP-binding  63.12 
 
 
700 aa  548  1e-155  Psychrobacter sp. PRwf-1  Bacteria  normal  normal 
 
 
-
 
NC_010552  BamMC406_5118  carbamoyl-phosphate synthase L chain ATP-binding  52.45 
 
 
666 aa  551  1e-155  Burkholderia ambifaria MC40-6  Bacteria  normal  normal 
 
 
-
 
NC_012856  Rpic12D_0123  Carbamoyl-phosphate synthase L chain ATP-binding  51.45 
 
 
674 aa  547  1e-154  Ralstonia pickettii 12D  Bacteria  normal  normal 
 
 
-
 
NC_008543  Bcen2424_5237  carbamoyl-phosphate synthase L chain, ATP-binding  51.87 
 
 
665 aa  543  1e-153  Burkholderia cenocepacia HI2424  Bacteria  normal  0.578975  normal  0.758885 
 
 
-
 
NC_011894  Mnod_0291  Carbamoyl-phosphate synthase L chain ATP-binding  67.62 
 
 
649 aa  542  1e-153  Methylobacterium nodulans ORS 2060  Bacteria  normal  0.647216  n/a   
 
 
-
 
NC_010682  Rpic_0116  Carbamoyl-phosphate synthase L chain ATP-binding  51.47 
 
 
674 aa  544  1e-153  Ralstonia pickettii 12J  Bacteria  normal  normal 
 
 
-
 
NC_010515  Bcenmc03_5035  carbamoyl-phosphate synthase L chain ATP-binding  51.87 
 
 
665 aa  543  1e-153  Burkholderia cenocepacia MC0-3  Bacteria  normal  0.70526  normal 
 
 
-
 
NC_008061  Bcen_3130  carbamoyl-phosphate synthase L chain, ATP-binding  51.87 
 
 
665 aa  543  1e-153  Burkholderia cenocepacia AU 1054  Bacteria  normal  n/a   
 
 
-
 
NC_010338  Caul_1876  carbamoyl-phosphate synthase L chain ATP-binding  53.78 
 
 
621 aa  541  9.999999999999999e-153  Caulobacter sp. K31  Bacteria  normal  normal 
 
 
-
 
NC_011662  Tmz1t_0751  Carbamoyl-phosphate synthase L chain ATP-binding  52.08 
 
 
667 aa  541  9.999999999999999e-153  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_007511  Bcep18194_B0426  3-methylcrotonoyl-CoA carboxylase, alpha subunit  51.87 
 
 
665 aa  538  1e-151  Burkholderia sp. 383  Bacteria  normal  0.967801  normal 
 
 
-
 
NC_009665  Shew185_2849  carbamoyl-phosphate synthase L chain ATP-binding  47.09 
 
 
686 aa  536  1e-151  Shewanella baltica OS185  Bacteria  normal  n/a   
 
 
-
 
NC_011663  Sbal223_1527  Carbamoyl-phosphate synthase L chain ATP-binding  47.09 
 
 
685 aa  535  1e-151  Shewanella baltica OS223  Bacteria  normal  normal 
 
 
-
 
NC_009997  Sbal195_2976  carbamoyl-phosphate synthase L chain ATP-binding  47.24 
 
 
680 aa  538  1e-151  Shewanella baltica OS195  Bacteria  normal  normal  0.870775 
 
 
-
 
NC_009052  Sbal_2831  carbamoyl-phosphate synthase L chain ATP-binding  46.8 
 
 
680 aa  534  1e-150  Shewanella baltica OS155  Bacteria  normal  n/a   
 
 
-
 
NC_011666  Msil_3434  Carbamoyl-phosphate synthase L chain ATP-binding  52.92 
 
 
626 aa  534  1e-150  Methylocella silvestris BL2  Bacteria  n/a    normal 
 
 
-
 
NC_004578  PSPTO_2736  biotin carboxylase/biotin-containing subunit  49.24 
 
 
649 aa  530  1e-149  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  n/a   
 
 
-
 
NC_006368  lpp1792  hypothetical protein  44.49 
 
 
654 aa  531  1e-149  Legionella pneumophila str. Paris  Bacteria  n/a    n/a   
 
 
-
 
NC_006369  lpl1793  hypothetical protein  44.29 
 
 
654 aa  530  1e-149  Legionella pneumophila str. Lens  Bacteria  n/a    n/a   
 
 
-
 
NC_009078  BURPS1106A_A1956  putative acetyl-CoA carboxylase, biotin carboxylase  52.62 
 
 
664 aa  530  1e-149  Burkholderia pseudomallei 1106a  Bacteria  normal  n/a   
 
 
-
 
NC_009438  Sputcn32_1716  carbamoyl-phosphate synthase L chain, ATP-binding  46.47 
 
 
689 aa  530  1e-149  Shewanella putrefaciens CN-32  Bacteria  normal  n/a   
 
 
-
 
NC_007794  Saro_1642  carbamoyl-phosphate synthase L chain, ATP-binding  65.6 
 
 
623 aa  530  1e-149  Novosphingobium aromaticivorans DSM 12444  Bacteria  normal  0.473054  n/a   
 
 
-
 
NC_009079  BMA10247_A1605  putative acetyl-CoA carboxylase, biotin carboxylase  52.02 
 
 
664 aa  526  1e-148  Burkholderia mallei NCTC 10247  Bacteria  normal  0.585456  n/a   
 
 
-
 
NC_008835  BMA10229_0651  putative acetyl-CoA carboxylase, biotin carboxylase  52.02 
 
 
664 aa  526  1e-148  Burkholderia mallei NCTC 10229  Bacteria  normal  0.547961  n/a   
 
 
-
 
NC_008784  BMASAVP1_0539  putative acetyl-CoA carboxylase, biotin carboxylase  52.02 
 
 
664 aa  526  1e-148  Burkholderia mallei SAVP1  Bacteria  normal  n/a   
 
 
-
 
NC_009727  CBUD_1070  methylcrotonyl-CoA carboxylase biotin-containing subunit  43.78 
 
 
661 aa  526  1e-148  Coxiella burnetii Dugway 5J108-111  Bacteria  normal  n/a   
 
 
-
 
NC_008577  Shewana3_1669  3-methylcrotonoyl-CoA carboxylase, alpha subunit  46.75 
 
 
674 aa  528  1e-148  Shewanella sp. ANA-3  Bacteria  normal  normal 
 
 
-
 
NC_010117  COXBURSA331_A0962  biotin carboxylase  43.78 
 
 
661 aa  526  1e-148  Coxiella burnetii RSA 331  Bacteria  normal  n/a   
 
 
-
 
NC_008228  Patl_2928  carbamoyl-phosphate synthase L chain, ATP-binding  46.35 
 
 
675 aa  526  1e-148  Pseudoalteromonas atlantica T6c  Bacteria  normal  0.321789  n/a   
 
 
-
 
NC_008463  PA14_38480  alpha subunit of geranoyl-CoA carboxylase, GnyA  50.83 
 
 
655 aa  525  1e-148  Pseudomonas aeruginosa UCBPP-PA14  Bacteria  normal  normal 
 
 
-
 
NC_008321  Shewmr4_2325  3-methylcrotonoyl-CoA carboxylase, alpha subunit  46.1 
 
 
679 aa  526  1e-148  Shewanella sp. MR-4  Bacteria  normal  normal  0.676879 
 
 
-
 
NC_008322  Shewmr7_2397  3-methylcrotonoyl-CoA carboxylase, alpha subunit  46.1 
 
 
679 aa  528  1e-148  Shewanella sp. MR-7  Bacteria  normal  0.63603  normal  0.616301 
 
 
-
 
NC_006349  BMAA0805  putative acetyl-CoA carboxylase, biotin carboxylase  52.02 
 
 
664 aa  523  1e-147  Burkholderia mallei ATCC 23344  Bacteria  normal  n/a   
 
 
-
 
NC_011138  MADE_02415  methylcrotonyl-CoA carboxylase, alpha subunit  46.5 
 
 
666 aa  523  1e-147  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  n/a   
 
 
-
 
NC_008740  Maqu_2807  carbamoyl-phosphate synthase L chain, ATP-binding  47.6 
 
 
652 aa  524  1e-147  Marinobacter aquaeolei VT8  Bacteria  normal  0.167198  n/a   
 
 
-
 
NC_007492  Pfl01_3659  3-methylcrotonoyl-CoA carboxylase, alpha subunit  48.54 
 
 
649 aa  521  1e-146  Pseudomonas fluorescens Pf0-1  Bacteria  hitchhiker  0.00262153  normal  0.0752572 
 
 
-
 
NC_009092  Shew_2573  carbamoyl-phosphate synthase L chain, ATP-binding  45.55 
 
 
677 aa  519  1e-146  Shewanella loihica PV-4  Bacteria  normal  normal 
 
 
-
 
NC_008700  Sama_1359  3-methylcrotonyl-CoA carboxylase alpha subunit  48.14 
 
 
673 aa  519  1e-146  Shewanella amazonensis SB2B  Bacteria  normal  normal  0.812437 
 
 
-
 
NC_010501  PputW619_1809  carbamoyl-phosphate synthase L chain ATP-binding  48.81 
 
 
650 aa  520  1e-146  Pseudomonas putida W619  Bacteria  normal  normal  0.202229 
 
 
-
 
NC_009656  PSPA7_3277  alpha subunit of geranoyl-CoA carboxylase, GnyA  50.38 
 
 
655 aa  521  1e-146  Pseudomonas aeruginosa PA7  Bacteria  normal  n/a   
 
 
-
 
NC_008228  Patl_0319  carbamoyl-phosphate synthase L chain, ATP-binding  44.14 
 
 
689 aa  521  1e-146  Pseudoalteromonas atlantica T6c  Bacteria  normal  n/a   
 
 
-
 
NC_004347  SO_1894  acetyl-CoA carboxylase, biotin carboxylase, putative  46.43 
 
 
694 aa  517  1.0000000000000001e-145  Shewanella oneidensis MR-1  Bacteria  n/a    n/a   
 
 
-
 
NC_007005  Psyr_2467  carbamoyl-phosphate synthase subunit L  49.23 
 
 
649 aa  516  1.0000000000000001e-145  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  0.30197  normal  0.0144387 
 
 
-
 
NC_008786  Veis_0847  carbamoyl-phosphate synthase L chain, ATP-binding  61.16 
 
 
730 aa  516  1.0000000000000001e-145  Verminephrobacter eiseniae EF01-2  Bacteria  normal  normal 
 
 
-
 
NC_013457  VEA_000380  methylcrotonyl-CoA carboxylase biotin-containing subunit  44.21 
 
 
686 aa  518  1.0000000000000001e-145  Vibrio sp. Ex25  Bacteria  normal  n/a   
 
 
-
 
NC_009439  Pmen_2030  3-methylcrotonoyl-CoA carboxylase, alpha subunit  49.7 
 
 
644 aa  514  1e-144  Pseudomonas mendocina ymp  Bacteria  normal  0.0317693  normal  0.435789 
 
 
-
 
NC_009439  Pmen_2694  carbamoyl-phosphate synthase L chain, ATP-binding  47.85 
 
 
661 aa  513  1e-144  Pseudomonas mendocina ymp  Bacteria  normal  0.250479  normal  0.322946 
 
 
-
 
NC_009512  Pput_1774  carbamoyl-phosphate synthase L chain, ATP-binding  48.2 
 
 
650 aa  509  1e-143  Pseudomonas putida F1  Bacteria  hitchhiker  0.00809985  hitchhiker  0.00202818 
 
 
-
 
NC_012560  Avin_49520  acetyl-CoA carboxylase, biotin carboxylase  50.37 
 
 
658 aa  509  1e-143  Azotobacter vinelandii DJ  Bacteria  normal  0.296412  n/a   
 
 
-
 
NC_009831  Ssed_1455  carbamoyl-phosphate synthase L chain, ATP-binding  44.27 
 
 
691 aa  512  1e-143  Shewanella sediminis HAW-EB3  Bacteria  normal  0.419117  normal 
 
 
-
 
NC_010322  PputGB1_3665  carbamoyl-phosphate synthase L chain ATP-binding  47.73 
 
 
650 aa  511  1e-143  Pseudomonas putida GB-1  Bacteria  hitchhiker  0.000243321  hitchhiker  0.000000000183935 
 
 
-
 
NC_008345  Sfri_2730  carbamoyl-phosphate synthase L chain, ATP-binding  46.45 
 
 
676 aa  509  1e-143  Shewanella frigidimarina NCIMB 400  Bacteria  normal  n/a   
 
 
-
 
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