119 homologs were found in PanDaTox collection
for query gene Maeo_0614 on replicon NC_009635
Organism: Methanococcus aeolicus Nankai-3



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_009635  Maeo_0614  bifunctional formaldehyde-activating enzyme/3-hexulose-6-phosphate synthase  100 
 
 
391 aa  783    Methanococcus aeolicus Nankai-3  Archaea  normal  n/a   
 
 
-
 
NC_007796  Mhun_1628  bifunctional formaldehyde-activating enzyme/3-hexulose-6-phosphate synthase  40.86 
 
 
393 aa  257  3e-67  Methanospirillum hungatei JF-1  Archaea  normal  normal 
 
 
-
 
NC_007955  Mbur_1994  bifunctional formaldehyde-activating enzyme/3-hexulose-6-phosphate synthase  40.55 
 
 
396 aa  257  3e-67  Methanococcoides burtonii DSM 6242  Archaea  normal  n/a   
 
 
-
 
NC_007355  Mbar_A0935  bifunctional formaldehyde-activating enzyme/3-hexulose-6-phosphate synthase  41.56 
 
 
392 aa  256  6e-67  Methanosarcina barkeri str. Fusaro  Archaea  hitchhiker  0.0033619  normal 
 
 
-
 
NC_009712  Mboo_0772  bifunctional formaldehyde-activating enzyme/3-hexulose-6-phosphate synthase  39.69 
 
 
393 aa  255  1.0000000000000001e-66  Candidatus Methanoregula boonei 6A8  Archaea  normal  normal  0.58783 
 
 
-
 
NC_009051  Memar_1085  bifunctional formaldehyde-activating enzyme/3-hexulose-6-phosphate synthase  41.01 
 
 
393 aa  248  2e-64  Methanoculleus marisnigri JR1  Archaea  normal  0.136979  n/a   
 
 
-
 
NC_011832  Mpal_1036  bifunctional formaldehyde-activating enzyme/3-hexulose-6-phosphate synthase  40.4 
 
 
393 aa  247  2e-64  Methanosphaerula palustris E1-9c  Archaea  normal  normal 
 
 
-
 
NC_008942  Mlab_0996  bifunctional formaldehyde-activating enzyme/3-hexulose-6-phosphate synthase  37.38 
 
 
403 aa  242  1e-62  Methanocorpusculum labreanum Z  Archaea  normal  normal  0.566431 
 
 
-
 
NC_008553  Mthe_0988  bifunctional formaldehyde-activating enzyme/3-hexulose-6-phosphate synthase  38.69 
 
 
392 aa  233  3e-60  Methanosaeta thermophila PT  Archaea  normal  n/a   
 
 
-
 
NC_013926  Aboo_0457  Orotidine 5'-phosphate decarboxylase  34.8 
 
 
426 aa  108  1e-22  Aciduliprofundum boonei T469  Archaea  normal  n/a   
 
 
-
 
NC_009975  MmarC6_1403  bifunctional hexulose-6-phosphate synthase/ribonuclease regulator  34.1 
 
 
438 aa  106  8e-22  Methanococcus maripaludis C6  Archaea  normal  0.175956  n/a   
 
 
-
 
NC_009954  Cmaq_1871  orotidine 5'-phosphate decarboxylase  37.26 
 
 
217 aa  105  1e-21  Caldivirga maquilingensis IC-167  Archaea  normal  0.563194  normal  0.356021 
 
 
-
 
CP001800  Ssol_1184  Orotidine 5'-phosphate decarboxylase  34.23 
 
 
225 aa  101  2e-20  Sulfolobus solfataricus 98/2  Archaea  normal  0.0998927  n/a   
 
 
-
 
NC_009135  MmarC5_0321  bifunctional hexulose-6-phosphate synthase/ribonuclease regulator  33.18 
 
 
438 aa  102  2e-20  Methanococcus maripaludis C5  Archaea  normal  n/a   
 
 
-
 
NC_009634  Mevan_0582  bifunctional hexulose-6-phosphate synthase/ribonuclease regulator  35.24 
 
 
437 aa  102  2e-20  Methanococcus vannielii SB  Archaea  normal  0.062003  n/a   
 
 
-
 
NC_009637  MmarC7_0516  bifunctional hexulose-6-phosphate synthase/ribonuclease regulator  33.18 
 
 
438 aa  101  3e-20  Methanococcus maripaludis C7  Archaea  normal  0.35671  normal 
 
 
-
 
NC_008553  Mthe_0455  bifunctional hexulose-6-phosphate synthase/ribonuclease regulator  35.92 
 
 
428 aa  97.1  5e-19  Methanosaeta thermophila PT  Archaea  normal  n/a   
 
 
-
 
NC_009440  Msed_0227  orotidine 5'-phosphate decarboxylase  32.09 
 
 
227 aa  96.3  9e-19  Metallosphaera sedula DSM 5348  Archaea  normal  decreased coverage  0.0096121 
 
 
-
 
NC_009712  Mboo_0707  bifunctional hexulose-6-phosphate synthase/ribonuclease regulator  36.54 
 
 
428 aa  94.7  2e-18  Candidatus Methanoregula boonei 6A8  Archaea  normal  normal  0.172064 
 
 
-
 
NC_007355  Mbar_A1170  bifunctional hexulose-6-phosphate synthase/ribonuclease regulator  38.98 
 
 
413 aa  94.7  3e-18  Methanosarcina barkeri str. Fusaro  Archaea  normal  normal 
 
 
-
 
NC_009051  Memar_0744  bifunctional hexulose-6-phosphate synthase/ribonuclease regulator  32.17 
 
 
429 aa  94  4e-18  Methanoculleus marisnigri JR1  Archaea  normal  0.225207  n/a   
 
 
-
 
NC_010525  Tneu_0708  orotidine 5'-phosphate decarboxylase  30.14 
 
 
222 aa  91.3  3e-17  Thermoproteus neutrophilus V24Sta  Archaea  normal  0.942951  normal 
 
 
-
 
NC_011832  Mpal_2121  bifunctional hexulose-6-phosphate synthase/ribonuclease regulator  35.38 
 
 
428 aa  90.1  6e-17  Methanosphaerula palustris E1-9c  Archaea  normal  normal 
 
 
-
 
NC_008942  Mlab_1453  bifunctional hexulose-6-phosphate synthase/ribonuclease regulator  31.4 
 
 
427 aa  87.8  3e-16  Methanocorpusculum labreanum Z  Archaea  normal  normal  0.395706 
 
 
-
 
NC_007796  Mhun_0647  bifunctional hexulose-6-phosphate synthase/ribonuclease regulator  30.91 
 
 
429 aa  83.2  0.000000000000007  Methanospirillum hungatei JF-1  Archaea  normal  0.101947  normal  0.0867495 
 
 
-
 
NC_008541  Arth_3708  hexulose-6-phosphate synthase  30.05 
 
 
207 aa  79.3  0.0000000000001  Arthrobacter sp. FB24  Bacteria  normal  n/a   
 
 
-
 
NC_013517  Sterm_3212  3-hexulose-6-phosphate synthase  30.77 
 
 
211 aa  78.6  0.0000000000002  Sebaldella termitidis ATCC 33386  Bacteria  normal  n/a   
 
 
-
 
NC_009376  Pars_1830  orotidine 5'-phosphate decarboxylase  35.51 
 
 
221 aa  76.3  0.0000000000009  Pyrobaculum arsenaticum DSM 13514  Archaea  hitchhiker  0.000143542  normal  0.0955115 
 
 
-
 
NC_008698  Tpen_0372  orotidine 5'-phosphate decarboxylase  29.41 
 
 
231 aa  73.9  0.000000000004  Thermofilum pendens Hrk 5  Archaea  normal  n/a   
 
 
-
 
NC_009073  Pcal_0568  hexulose-6-phosphate synthase  30.5 
 
 
217 aa  73.9  0.000000000004  Pyrobaculum calidifontis JCM 11548  Archaea  n/a    normal 
 
 
-
 
NC_014148  Plim_1285  formaldehyde-activating enzyme  36.65 
 
 
165 aa  73.9  0.000000000005  Planctomyces limnophilus DSM 3776  Bacteria  normal  n/a   
 
 
-
 
NC_011083  SeHA_C2929  3-hexulose-6-phosphate synthase  29.55 
 
 
211 aa  73.9  0.000000000005  Salmonella enterica subsp. enterica serovar Heidelberg str. SL476  Bacteria  normal  hitchhiker  0.0000000015488 
 
 
-
 
NC_008701  Pisl_1686  orotidine 5'-phosphate decarboxylase  34.06 
 
 
221 aa  70.9  0.00000000003  Pyrobaculum islandicum DSM 4184  Archaea  normal  normal  0.0279692 
 
 
-
 
NC_007955  Mbur_0367  formaldehyde-activating enzyme  33.96 
 
 
160 aa  70.1  0.00000000006  Methanococcoides burtonii DSM 6242  Archaea  normal  0.203725  n/a   
 
 
-
 
NC_013526  Tter_2273  Orotidine 5'-phosphate decarboxylase  28.43 
 
 
240 aa  70.1  0.00000000007  Thermobaculum terrenum ATCC BAA-798  Bacteria  normal  n/a   
 
 
-
 
NC_013132  Cpin_5671  Orotidine 5'-phosphate decarboxylase  31.28 
 
 
211 aa  69.7  0.00000000008  Chitinophaga pinensis DSM 2588  Bacteria  normal  normal  0.587401 
 
 
-
 
CP001509  ECD_03433  3-keto-L-gulonate 6-phosphate decarboxylase  28.64 
 
 
220 aa  68.9  0.0000000001  Escherichia coli BL21(DE3)  Bacteria  normal  n/a   
 
 
-
 
NC_002976  SERP0216  hexulose-6-phosphate synthase, putative  26.73 
 
 
210 aa  68.9  0.0000000001  Staphylococcus epidermidis RP62A  Bacteria  normal  n/a   
 
 
-
 
NC_012892  B21_03384  hypothetical protein  28.64 
 
 
220 aa  68.9  0.0000000001  Escherichia coli BL21  Bacteria  normal  n/a   
 
 
-
 
NC_011083  SeHA_C3998  3-keto-L-gulonate-6-phosphate decarboxylase  29.67 
 
 
220 aa  68.6  0.0000000002  Salmonella enterica subsp. enterica serovar Heidelberg str. SL476  Bacteria  normal  normal  0.92923 
 
 
-
 
CP001637  EcDH1_0129  3-dehydro-L-gulonate-6-phosphate decarboxylase  28.16 
 
 
220 aa  67.8  0.0000000003  Escherichia coli DH1  Bacteria  normal  n/a   
 
 
-
 
NC_009800  EcHS_A3785  3-keto-L-gulonate-6-phosphate decarboxylase  28.16 
 
 
220 aa  67.8  0.0000000003  Escherichia coli HS  Bacteria  normal  n/a   
 
 
-
 
NC_010468  EcolC_0133  3-keto-L-gulonate-6-phosphate decarboxylase  28.16 
 
 
220 aa  67.8  0.0000000003  Escherichia coli ATCC 8739  Bacteria  normal  normal 
 
 
-
 
NC_011094  SeSA_A3873  3-keto-L-gulonate-6-phosphate decarboxylase  29.67 
 
 
216 aa  67.8  0.0000000003  Salmonella enterica subsp. enterica serovar Schwarzengrund str. CVM19633  Bacteria  normal  normal 
 
 
-
 
NC_011149  SeAg_B3889  3-keto-L-gulonate-6-phosphate decarboxylase  29.67 
 
 
220 aa  67.8  0.0000000003  Salmonella enterica subsp. enterica serovar Agona str. SL483  Bacteria  normal  n/a   
 
 
-
 
NC_010498  EcSMS35_3904  3-keto-L-gulonate-6-phosphate decarboxylase  28.64 
 
 
220 aa  67.4  0.0000000004  Escherichia coli SMS-3-5  Bacteria  normal  normal 
 
 
-
 
NC_011205  SeD_A4060  3-keto-L-gulonate-6-phosphate decarboxylase  29.67 
 
 
220 aa  67.4  0.0000000004  Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853  Bacteria  normal  normal 
 
 
-
 
NC_009801  EcE24377A_4078  3-keto-L-gulonate-6-phosphate decarboxylase  28.16 
 
 
220 aa  67  0.0000000005  Escherichia coli E24377A  Bacteria  normal  n/a   
 
 
-
 
NC_007355  Mbar_A2060  formaldehyde-activating enzyme  32.7 
 
 
178 aa  66.6  0.0000000006  Methanosarcina barkeri str. Fusaro  Archaea  normal  0.189028  normal  0.41416 
 
 
-
 
NC_002977  MCA3043  hexulose-6-phosphate synthase  28.5 
 
 
215 aa  66.6  0.0000000007  Methylococcus capsulatus str. Bath  Bacteria  normal  0.146405  n/a   
 
 
-
 
NC_002977  MCA3049  hexulose-6-phosphate synthase  28.5 
 
 
215 aa  66.6  0.0000000007  Methylococcus capsulatus str. Bath  Bacteria  normal  n/a   
 
 
-
 
NC_011080  SNSL254_A3953  3-keto-L-gulonate-6-phosphate decarboxylase  27.67 
 
 
220 aa  66.2  0.0000000008  Salmonella enterica subsp. enterica serovar Newport str. SL254  Bacteria  normal  0.362563  normal 
 
 
-
 
NC_009720  Xaut_0032  formaldehyde-activating protein  32.08 
 
 
169 aa  65.5  0.000000001  Xanthobacter autotrophicus Py2  Bacteria  normal  normal  0.848098 
 
 
-
 
NC_007947  Mfla_1654  orotidine 5'-phosphate decarboxylase  30.53 
 
 
209 aa  65.5  0.000000002  Methylobacillus flagellatus KT  Bacteria  unclonable  0.000000000168104  normal  0.271517 
 
 
-
 
NC_009477  SaurJH9_2736  orotidine 5'-phosphate decarboxylase  26.11 
 
 
210 aa  64.7  0.000000002  Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  n/a   
 
 
-
 
NC_009619  SaurJH1_2812  orotidine 5'-phosphate decarboxylase  26.11 
 
 
210 aa  64.7  0.000000002  Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  n/a   
 
 
-
 
NC_002977  MCA2738  hexulose-6-phosphate synthase/SIS domain-containing protein  28.99 
 
 
389 aa  64.7  0.000000003  Methylococcus capsulatus str. Bath  Bacteria  normal  n/a   
 
 
-
 
NC_010505  Mrad2831_0533  formaldehyde-activating enzyme  30.72 
 
 
170 aa  64.3  0.000000003  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  normal 
 
 
-
 
NC_010725  Mpop_1785  formaldehyde-activating enzyme  30.72 
 
 
170 aa  64.7  0.000000003  Methylobacterium populi BJ001  Bacteria  normal  normal 
 
 
-
 
NC_008825  Mpe_A2612  formaldehyde-activating enzyme  31.21 
 
 
169 aa  63.9  0.000000005  Methylibium petroleiphilum PM1  Bacteria  normal  0.0416881  normal 
 
 
-
 
NC_010524  Lcho_3147  formaldehyde-activating enzyme  32.92 
 
 
169 aa  63.9  0.000000005  Leptothrix cholodnii SP-6  Bacteria  n/a    normal 
 
 
-
 
NC_007947  Mfla_0250  hexulose-6-phosphate synthase  29.17 
 
 
228 aa  63.2  0.000000008  Methylobacillus flagellatus KT  Bacteria  unclonable  0.00000000013709  normal  0.0274377 
 
 
-
 
NC_007947  Mfla_2524  putative formaldehyde-activating enzyme  32.37 
 
 
183 aa  62.4  0.00000001  Methylobacillus flagellatus KT  Bacteria  normal  normal 
 
 
-
 
NC_010172  Mext_1834  formaldehyde-activating enzyme  30.12 
 
 
170 aa  62.4  0.00000001  Methylobacterium extorquens PA1  Bacteria  normal  normal 
 
 
-
 
NC_010511  M446_5783  formaldehyde-activating enzyme  31.29 
 
 
171 aa  62.8  0.00000001  Methylobacterium sp. 4-46  Bacteria  normal  0.0971644  normal 
 
 
-
 
NC_011757  Mchl_2169  formaldehyde-activating enzyme  30.12 
 
 
170 aa  62.4  0.00000001  Methylobacterium chloromethanicum CM4  Bacteria  normal  0.783809  normal  0.178175 
 
 
-
 
NC_011894  Mnod_6007  formaldehyde-activating enzyme  30.72 
 
 
171 aa  62.4  0.00000001  Methylobacterium nodulans ORS 2060  Bacteria  normal  0.100814  n/a   
 
 
-
 
NC_012917  PC1_3696  3-keto-L-gulonate-6-phosphate decarboxylase  28.7 
 
 
218 aa  61.6  0.00000002  Pectobacterium carotovorum subsp. carotovorum PC1  Bacteria  normal  n/a   
 
 
-
 
NC_013517  Sterm_1849  3-hexulose-6-phosphate synthase  28.42 
 
 
212 aa  60.8  0.00000004  Sebaldella termitidis ATCC 33386  Bacteria  normal  n/a   
 
 
-
 
NC_009487  SaurJH9_0593  orotidine 5'-phosphate decarboxylase  26.7 
 
 
210 aa  60.5  0.00000005  Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  n/a   
 
 
-
 
NC_009632  SaurJH1_0607  orotidine 5'-phosphate decarboxylase  26.7 
 
 
210 aa  60.5  0.00000005  Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  n/a   
 
 
-
 
NC_002977  MCA2866  formaldehyde-activating enzyme  31.01 
 
 
170 aa  59.7  0.00000008  Methylococcus capsulatus str. Bath  Bacteria  normal  n/a   
 
 
-
 
NC_013421  Pecwa_3893  3-keto-L-gulonate-6-phosphate decarboxylase  27.98 
 
 
218 aa  59.7  0.00000008  Pectobacterium wasabiae WPP163  Bacteria  normal  n/a   
 
 
-
 
NC_011666  Msil_2390  formaldehyde-activating enzyme  31.06 
 
 
175 aa  59.7  0.00000008  Methylocella silvestris BL2  Bacteria  n/a    normal 
 
 
-
 
NC_007952  Bxe_B2436  formaldehyde-activating protein  29.75 
 
 
169 aa  59.3  0.0000001  Burkholderia xenovorans LB400  Bacteria  normal  normal  0.397979 
 
 
-
 
NC_010623  Bphy_5474  formaldehyde-activating enzyme  30.36 
 
 
177 aa  58.9  0.0000001  Burkholderia phymatum STM815  Bacteria  normal  0.0338658  normal  0.0655052 
 
 
-
 
NC_010625  Bphy_6487  formaldehyde-activating enzyme  28.48 
 
 
169 aa  59.3  0.0000001  Burkholderia phymatum STM815  Bacteria  normal  0.497311  normal  0.302319 
 
 
-
 
NC_009832  Spro_3937  3-keto-L-gulonate-6-phosphate decarboxylase  28.32 
 
 
218 aa  58.2  0.0000003  Serratia proteamaculans 568  Bacteria  normal  normal 
 
 
-
 
NC_011666  Msil_1799  formaldehyde-activating enzyme  35.34 
 
 
178 aa  56.6  0.0000007  Methylocella silvestris BL2  Bacteria  n/a    normal 
 
 
-
 
NC_012791  Vapar_3079  formaldehyde-activating enzyme  30.67 
 
 
170 aa  55.8  0.000001  Variovorax paradoxus S110  Bacteria  normal  n/a   
 
 
-
 
NC_008528  OEOE_0131  hexulose-6-phosphate synthase  23.79 
 
 
207 aa  55.5  0.000002  Oenococcus oeni PSU-1  Bacteria  normal  n/a   
 
 
-
 
NC_008825  Mpe_A2627  putative formaldehyde-activating enzyme  30.3 
 
 
177 aa  55.1  0.000002  Methylibium petroleiphilum PM1  Bacteria  normal  0.212894  normal 
 
 
-
 
NC_012791  Vapar_3063  formaldehyde-activating enzyme  28.99 
 
 
177 aa  55.5  0.000002  Variovorax paradoxus S110  Bacteria  normal  n/a   
 
 
-
 
NC_009720  Xaut_1365  formaldehyde-activating protein  29.81 
 
 
191 aa  54.3  0.000004  Xanthobacter autotrophicus Py2  Bacteria  normal  0.745489  normal 
 
 
-
 
NC_010524  Lcho_3132  formaldehyde-activating enzyme  33.12 
 
 
181 aa  54.3  0.000004  Leptothrix cholodnii SP-6  Bacteria  n/a    normal 
 
 
-
 
NC_012880  Dd703_0115  3-keto-L-gulonate-6-phosphate decarboxylase  33.33 
 
 
215 aa  52.8  0.000009  Dickeya dadantii Ech703  Bacteria  normal  0.0197016  n/a   
 
 
-
 
NC_010172  Mext_1450  formaldehyde-activating enzyme  32.8 
 
 
179 aa  52.4  0.00001  Methylobacterium extorquens PA1  Bacteria  normal  normal  0.485811 
 
 
-
 
NC_011757  Mchl_1725  formaldehyde-activating enzyme  32.8 
 
 
179 aa  52.4  0.00001  Methylobacterium chloromethanicum CM4  Bacteria  normal  0.393787  normal  0.0143668 
 
 
-
 
NC_010511  M446_4369  formaldehyde-activating enzyme  29.94 
 
 
181 aa  51.6  0.00002  Methylobacterium sp. 4-46  Bacteria  normal  0.279882  normal 
 
 
-
 
NC_014148  Plim_3519  formaldehyde-activating enzyme  30.25 
 
 
211 aa  51.2  0.00003  Planctomyces limnophilus DSM 3776  Bacteria  normal  n/a   
 
 
-
 
NC_009051  Memar_0975  formaldehyde-activating enzyme  31.65 
 
 
167 aa  50.8  0.00004  Methanoculleus marisnigri JR1  Archaea  normal  0.0927434  n/a   
 
 
-
 
NC_011894  Mnod_4915  formaldehyde-activating enzyme  31.75 
 
 
181 aa  50.4  0.00005  Methylobacterium nodulans ORS 2060  Bacteria  normal  0.090523  n/a   
 
 
-
 
NC_009720  Xaut_1627  formaldehyde-activating protein  33.08 
 
 
179 aa  50.1  0.00008  Xanthobacter autotrophicus Py2  Bacteria  normal  0.67854  normal 
 
 
-
 
NC_012912  Dd1591_0292  3-keto-L-gulonate-6-phosphate decarboxylase  33.33 
 
 
214 aa  49.3  0.0001  Dickeya zeae Ech1591  Bacteria  normal  0.0962107  n/a   
 
 
-
 
NC_009456  VC0395_0987  3-keto-L-gulonate-6-phosphate decarboxylase  24.67 
 
 
215 aa  48.1  0.0002  Vibrio cholerae O395  Bacteria  normal  0.304875  n/a   
 
 
-
 
NC_010725  Mpop_1445  formaldehyde-activating enzyme  31.2 
 
 
179 aa  48.5  0.0002  Methylobacterium populi BJ001  Bacteria  normal  normal  0.318243 
 
 
-
 
NC_013517  Sterm_0145  3-dehydro-L-gulonate-6-phosphate decarboxylase  24.78 
 
 
212 aa  47.4  0.0004  Sebaldella termitidis ATCC 33386  Bacteria  normal  n/a   
 
 
-
 
NC_010505  Mrad2831_2016  formaldehyde-activating enzyme  30.65 
 
 
179 aa  47.8  0.0004  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  0.560353  normal  0.585828 
 
 
-
 
NC_013517  Sterm_0127  3-dehydro-L-gulonate-6-phosphate decarboxylase  24.78 
 
 
212 aa  47.4  0.0004  Sebaldella termitidis ATCC 33386  Bacteria  normal  n/a   
 
 
-
 
NC_011149  SeAg_B4664  3-keto-L-gulonate-6-phosphate decarboxylase  25.23 
 
 
216 aa  47.4  0.0005  Salmonella enterica subsp. enterica serovar Agona str. SL483  Bacteria  normal  0.482194  n/a   
 
 
-
 
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