More than 300 homologs were found in PanDaTox collection
for query gene Pisl_0104 on replicon NC_008701
Organism: Pyrobaculum islandicum DSM 4184



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Replicon accession
Locus tag
Product
% identity
Alignment on query gene
Alignment on homolog gene
Length
Bit score

E-value
Organism name
Kingdom
Plasmid clonability
Plasmid unclonability p-value
Fosmid clonability
Fosmid unclonability p-value
Coverage Plot
PanDaTox homologs
Experimental validation
NC_008701  Pisl_0104  tetrahydrofolate dehydrogenase/cyclohydrolase  100 
 
 		 311 aa  623  1e-177  Pyrobaculum islandicum DSM 4184  Archaea  normal  0.0409732  normal  1 
 
 
-
 
NC_010525  Tneu_1909  methylenetetrahydrofolate dehydrogenase (NADP(+))  85.85 
 
 		 311 aa  517  1e-146  Thermoproteus neutrophilus V24Sta  Archaea  decreased coverage  0.000677718  normal  0.128415 
 
 
-
 
NC_009376  Pars_2192  tetrahydrofolate dehydrogenase/cyclohydrolase  70.65 
 
 		 311 aa  439  9.999999999999999e-123  Pyrobaculum arsenaticum DSM 13514  Archaea  normal  1  normal  1 
 
 
-
 
NC_009073  Pcal_1897  methenyltetrahydrofolate cyclohydrolase  73.44 
 
 		 308 aa  432  1e-120  Pyrobaculum calidifontis JCM 11548  Archaea  n/a    normal  1 
 
 
-
 
NC_012034  Athe_0982  Methenyltetrahydrofolate cyclohydrolase  38.44 
 
 		 289 aa  199  6e-50  Anaerocellum thermophilum DSM 6725  Bacteria  hitchhiker  0.000669614  n/a   
 
 
-
 
NC_009714  CHAB381_1036  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  38.49 
 
 		 284 aa  189  5e-47  Campylobacter hominis ATCC BAA-381  Bacteria  normal  1  n/a   
 
 
-
 
NC_012029  Hlac_1624  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  38.72 
 
 		 307 aa  185  7e-46  Halorubrum lacusprofundi ATCC 49239  Archaea  normal  1  normal  1 
 
 
-
 
NC_009674  Bcer98_2874  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  39.46 
 
 		 286 aa  184  2.0000000000000003e-45  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  0.126852  n/a   
 
 
-
 
NC_007644  Moth_1516  methenyltetrahydrofolate cyclohydrolase  39.66 
 
 		 280 aa  184  2.0000000000000003e-45  Moorella thermoacetica ATCC 39073  Bacteria  normal  1  normal  1 
 
 
-
 
NC_010831  Cphamn1_1442  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  39.79 
 
 		 298 aa  183  4.0000000000000006e-45  Chlorobium phaeobacteroides BS1  Bacteria  normal  0.56836  normal  1 
 
 
-
 
NC_005945  BAS4085  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  39.12 
 
 		 286 aa  182  5.0000000000000004e-45  Bacillus anthracis str. Sterne  Bacteria  hitchhiker  0.00334729  n/a   
 
 
-
 
NC_007530  GBAA_4405  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  39.12 
 
 		 286 aa  182  5.0000000000000004e-45  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  1  n/a   
 
 
-
 
NC_011126  HY04AAS1_0893  Methenyltetrahydrofolate cyclohydrolase  39.45 
 
 		 278 aa  182  6e-45  Hydrogenobaculum sp. Y04AAS1  Bacteria  normal  1  n/a   
 
 
-
 
NC_011773  BCAH820_4201  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  38.78 
 
 		 286 aa  181  1e-44  Bacillus cereus AH820  Bacteria  n/a    hitchhiker  3.73931e-16 
 
 
-
 
NC_005957  BT9727_3923  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  38.78 
 
 		 286 aa  181  1e-44  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  1  n/a   
 
 
-
 
NC_011772  BCG9842_B0943  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  39.12 
 
 		 286 aa  181  1e-44  Bacillus cereus G9842  Bacteria  normal  1  hitchhiker  0.00348961 
 
 
-
 
NC_011725  BCB4264_A4291  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  39.12 
 
 		 286 aa  181  1e-44  Bacillus cereus B4264  Bacteria  normal  1  n/a   
 
 
-
 
NC_006274  BCZK3934  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  38.78 
 
 		 286 aa  180  2e-44  Bacillus cereus E33L  Bacteria  normal  0.0428362  n/a   
 
 
-
 
NC_010184  BcerKBAB4_4033  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  39.46 
 
 		 286 aa  181  2e-44  Bacillus weihenstephanensis KBAB4  Bacteria  normal  0.781388  n/a   
 
 
-
 
NC_009632  SaurJH1_1145  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  37.41 
 
 		 286 aa  180  2.9999999999999997e-44  Staphylococcus aureus subsp. aureus JH1  Bacteria  hitchhiker  0.00105319  n/a   
 
 
-
 
NC_011059  Paes_1178  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  38.08 
 
 		 295 aa  180  2.9999999999999997e-44  Prosthecochloris aestuarii DSM 271  Bacteria  normal  1  normal  0.545639 
 
 
-
 
NC_011658  BCAH187_A4311  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  38.78 
 
 		 286 aa  180  2.9999999999999997e-44  Bacillus cereus AH187  Bacteria  normal  0.0277859  n/a   
 
 
-
 
NC_009487  SaurJH9_1123  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  37.41 
 
 		 286 aa  180  2.9999999999999997e-44  Staphylococcus aureus subsp. aureus JH9  Bacteria  hitchhiker  0.000919852  n/a   
 
 
-
 
NC_003909  BCE_4254  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  38.44 
 
 		 286 aa  179  7e-44  Bacillus cereus ATCC 10987  Bacteria  normal  0.246013  n/a   
 
 
-
 
NC_007512  Plut_0927  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  40.88 
 
 		 307 aa  178  1e-43  Chlorobium luteolum DSM 273  Bacteria  normal  1  normal  1 
 
 
-
 
NC_013385  Adeg_1278  Methylenetetrahydrofolate dehydrogenase (NADP(+))  39.59 
 
 		 282 aa  177  2e-43  Ammonifex degensii KC4  Bacteria  normal  0.568567  n/a   
 
 
-
 
NC_009012  Cthe_1093  methenyltetrahydrofolate cyclohydrolase  37.04 
 
 		 285 aa  177  2e-43  Clostridium thermocellum ATCC 27405  Bacteria  hitchhiker  0.000000512009  n/a   
 
 
-
 
NC_010424  Daud_0103  methenyltetrahydrofolate cyclohydrolase  38.75 
 
 		 294 aa  176  3e-43  Candidatus Desulforudis audaxviator MP104C  Bacteria  normal  1  n/a   
 
 
-
 
NC_002976  SERP0648  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  35.96 
 
 		 286 aa  176  6e-43  Staphylococcus epidermidis RP62A  Bacteria  normal  1  n/a   
 
 
-
 
NC_013202  Hmuk_2214  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  38.54 
 
 		 297 aa  176  7e-43  Halomicrobium mukohataei DSM 12286  Archaea  normal  0.621742  normal  0.605059 
 
 
-
 
NC_007514  Cag_0779  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  37.42 
 
 		 295 aa  174  9.999999999999999e-43  Chlorobium chlorochromatii CaD3  Bacteria  normal  1  n/a   
 
 
-
 
NC_011060  Ppha_1205  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  41.91 
 
 		 295 aa  174  1.9999999999999998e-42  Pelodictyon phaeoclathratiforme BU-1  Bacteria  normal  1  n/a   
 
 
-
 
NC_013158  Huta_2943  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  38.21 
 
 		 297 aa  173  2.9999999999999996e-42  Halorhabdus utahensis DSM 12940  Archaea  normal  0.420051  n/a   
 
 
-
 
NC_012039  Cla_0581  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  36.99 
 
 		 298 aa  173  2.9999999999999996e-42  Campylobacter lari RM2100  Bacteria  normal  0.388564  n/a   
 
 
-
 
NC_010803  Clim_1112  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  41.61 
 
 		 296 aa  173  2.9999999999999996e-42  Chlorobium limicola DSM 245  Bacteria  normal  1  n/a   
 
 
-
 
NC_013743  Htur_1699  Methenyltetrahydrofolate cyclohydrolase  38.21 
 
 		 297 aa  172  3.9999999999999995e-42  Haloterrigena turkmenica DSM 5511  Archaea  n/a    n/a   
 
 
-
 
NC_009483  Gura_1169  methylenetetrahydrofolate dehydrogenase (NADP(+))  40.66 
 
 		 280 aa  172  5e-42  Geobacter uraniireducens Rf4  Bacteria  hitchhiker  0.00000103166  n/a   
 
 
-
 
NC_010655  Amuc_1641  Methenyltetrahydrofolate cyclohydrolase  36.67 
 
 		 291 aa  172  6.999999999999999e-42  Akkermansia muciniphila ATCC BAA-835  Bacteria  normal  1  normal  0.794405 
 
 
-
 
NC_002939  GSU0862  folD bifunctional protein  40.07 
 
 		 285 aa  172  7.999999999999999e-42  Geobacter sulfurreducens PCA  Bacteria  normal  1  n/a   
 
 
-
 
NC_011898  Ccel_0604  tetrahydrofolate dehydrogenase/cyclohydrolase  37.28 
 
 		 284 aa  171  1e-41  Clostridium cellulolyticum H10  Bacteria  normal  1  n/a   
 
 
-
 
NC_010718  Nther_1700  5,10-methylenetetrahydrofolate dehydrogenase (NADP+), Methenyltetrahydrofolate cyclohydrolase  38.75 
 
 		 284 aa  171  1e-41  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  1  normal  0.335496 
 
 
-
 
NC_013517  Sterm_1178  Methylenetetrahydrofolate dehydrogenase (NADP(+))  38.57 
 
 		 285 aa  171  1e-41  Sebaldella termitidis ATCC 33386  Bacteria  hitchhiker  0.0000000836934  n/a   
 
 
-
 
NC_008576  Mmc1_3712  methenyltetrahydrofolate cyclohydrolase  39.06 
 
 		 285 aa  171  1e-41  Magnetococcus sp. MC-1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009715  CCV52592_0799  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  36.59 
 
 		 288 aa  172  1e-41  Campylobacter curvus 525.92  Bacteria  normal  1  n/a   
 
 
-
 
NC_009802  CCC13826_0832  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  35.84 
 
 		 283 aa  170  2e-41  Campylobacter concisus 13826  Bacteria  normal  0.048214  n/a   
 
 
-
 
NC_010085  Nmar_1117  methylenetetrahydrofolate dehydrogenase  36.05 
 
 		 287 aa  171  2e-41  Nitrosopumilus maritimus SCM1  Archaea  n/a    normal  0.434415 
 
 
-
 
NC_007413  Ava_2703  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  38.49 
 
 		 299 aa  171  2e-41  Anabaena variabilis ATCC 29413  Bacteria  hitchhiker  0.00240961  normal  0.676317 
 
 
-
 
NC_013922  Nmag_2300  Methenyltetrahydrofolate cyclohydrolase  38.49 
 
 		 297 aa  170  3e-41  Natrialba magadii ATCC 43099  Archaea  normal  1  n/a   
 
 
-
 
NC_014248  Aazo_1506  methenyltetrahydrofolate cyclohydrolase  37.33 
 
 		 294 aa  169  5e-41  'Nostoc azollae' 0708  Bacteria  normal  1  n/a   
 
 
-
 
NC_013161  Cyan8802_1617  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  37.11 
 
 		 292 aa  169  6e-41  Cyanothece sp. PCC 8802  Bacteria  normal  1  normal  1 
 
 
-
 
NC_008609  Ppro_0480  methenyltetrahydrofolate cyclohydrolase  40.51 
 
 		 283 aa  169  6e-41  Pelobacter propionicus DSM 2379  Bacteria  hitchhiker  0.00000146162  n/a   
 
 
-
 
NC_008639  Cpha266_0997  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  38.54 
 
 		 308 aa  169  6e-41  Chlorobium phaeobacteroides DSM 266  Bacteria  normal  1  n/a   
 
 
-
 
NC_010730  SYO3AOP1_1067  Methenyltetrahydrofolate cyclohydrolase  38.01 
 
 		 285 aa  169  7e-41  Sulfurihydrogenibium sp. YO3AOP1  Bacteria  normal  1  n/a   
 
 
-
 
NC_011726  PCC8801_1592  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  37.11 
 
 		 292 aa  169  8e-41  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_008599  CFF8240_1174  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  35.07 
 
 		 283 aa  169  8e-41  Campylobacter fetus subsp. fetus 82-40  Bacteria  normal  0.840508  n/a   
 
 
-
 
NC_013512  Sdel_0845  Methylenetetrahydrofolate dehydrogenase (NADP(+))  37.01 
 
 		 281 aa  168  9e-41  Sulfurospirillum deleyianum DSM 6946  Bacteria  normal  1  n/a   
 
 
-
 
NC_011899  Hore_06480  tetrahydrofolate dehydrogenase/cyclohydrolase  36.33 
 
 		 283 aa  168  1e-40  Halothermothrix orenii H 168  Bacteria  hitchhiker  0.000000303472  n/a   
 
 
-
 
NC_014158  Tpau_0941  Methylenetetrahydrofolate dehydrogenase (NADP(+))  39.04 
 
 		 294 aa  168  1e-40  Tsukamurella paurometabola DSM 20162  Bacteria  normal  1  n/a   
 
 
-
 
NC_011884  Cyan7425_0973  Methylenetetrahydrofolate dehydrogenase (NADP(+))  39.43 
 
 		 293 aa  168  1e-40  Cyanothece sp. PCC 7425  Bacteria  normal  0.150063  normal  0.215441 
 
 
-
 
NC_011758  Mchl_5700  Methenyltetrahydrofolate cyclohydrolase  37.28 
 
 		 306 aa  168  1e-40  Methylobacterium chloromethanicum CM4  Bacteria  normal  1  normal  1 
 
 
-
 
NC_012918  GM21_2719  Methylenetetrahydrofolate dehydrogenase (NADP(+))  38.6 
 
 		 281 aa  167  2e-40  Geobacter sp. M21  Bacteria  n/a    normal  1 
 
 
-
 
NC_010322  PputGB1_2105  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  37.16 
 
 		 303 aa  167  2e-40  Pseudomonas putida GB-1  Bacteria  normal  0.538628  normal  0.603824 
 
 
-
 
NC_007633  MCAP_0706  methylene-tetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase  38.08 
 
 		 284 aa  167  2e-40  Mycoplasma capricolum subsp. capricolum ATCC 27343  Bacteria  normal  1  n/a   
 
 
-
 
NC_008148  Rxyl_0827  methenyltetrahydrofolate cyclohydrolase  37.87 
 
 		 284 aa  167  2e-40  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  0.997708  n/a   
 
 
-
 
NC_008527  LACR_0921  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  37.37 
 
 		 295 aa  167  2e-40  Lactococcus lactis subsp. cremoris SK11  Bacteria  unclonable  0.0000659615  n/a   
 
 
-
 
NC_013456  VEA_004081  methylenetetrahydrofolate dehydrogenase (NADP+)/methenyltetrahydrofolate cyclohydrolase  38.75 
 
 		 286 aa  167  2e-40  Vibrio sp. Ex25  Bacteria  normal  0.897306  n/a   
 
 
-
 
NC_007575  Suden_1113  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  35.74 
 
 		 285 aa  166  2.9999999999999998e-40  Sulfurimonas denitrificans DSM 1251  Bacteria  normal  0.947222  n/a   
 
 
-
 
NC_011146  Gbem_1497  tetrahydrofolate dehydrogenase/cyclohydrolase  36.27 
 
 		 281 aa  167  2.9999999999999998e-40  Geobacter bemidjiensis Bem  Bacteria  hitchhiker  0.0000244416  n/a   
 
 
-
 
NC_011832  Mpal_0744  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  36.54 
 
 		 280 aa  166  2.9999999999999998e-40  Methanosphaerula palustris E1-9c  Archaea  normal  1  normal  1 
 
 
-
 
NC_002967  TDE0013  methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase  36.45 
 
 		 293 aa  166  4e-40  Treponema denticola ATCC 35405  Bacteria  normal  1  n/a   
 
 
-
 
NC_009439  Pmen_3458  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  35.57 
 
 		 303 aa  166  4e-40  Pseudomonas mendocina ymp  Bacteria  normal  1  normal  1 
 
 
-
 
NC_013501  Rmar_0952  Methenyltetrahydrofolate cyclohydrolase  39.34 
 
 		 293 aa  166  5.9999999999999996e-40  Rhodothermus marinus DSM 4252  Bacteria  normal  1  n/a   
 
 
-
 
NC_003912  CJE0942  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  36.52 
 
 		 282 aa  166  5.9999999999999996e-40  Campylobacter jejuni RM1221  Bacteria  normal  1  n/a   
 
 
-
 
NC_009253  Dred_1073  methylenetetrahydrofolate dehydrogenase (NADP(+))  36.86 
 
 		 284 aa  166  6.9999999999999995e-40  Desulfotomaculum reducens MI-1  Bacteria  normal  0.174822  n/a   
 
 
-
 
NC_008312  Tery_4172  methenyltetrahydrofolate cyclohydrolase  36.43 
 
 		 287 aa  166  6.9999999999999995e-40  Trichodesmium erythraeum IMS101  Bacteria  normal  1  normal  0.280923 
 
 
-
 
NC_009439  Pmen_3471  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  35.55 
 
 		 307 aa  165  9e-40  Pseudomonas mendocina ymp  Bacteria  normal  1  normal  1 
 
 
-
 
NC_007517  Gmet_1162  methenyltetrahydrofolate cyclohydrolase  36.39 
 
 		 285 aa  165  9e-40  Geobacter metallireducens GS-15  Bacteria  hitchhiker  0.00000000377219  hitchhiker  0.00798692 
 
 
-
 
NC_008787  CJJ81176_0871  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  36.52 
 
 		 282 aa  164  1.0000000000000001e-39  Campylobacter jejuni subsp. jejuni 81-176  Bacteria  normal  0.0134315  n/a   
 
 
-
 
NC_011666  Msil_1881  Methenyltetrahydrofolate cyclohydrolase  36.01 
 
 		 318 aa  164  2.0000000000000002e-39  Methylocella silvestris BL2  Bacteria  n/a    normal  1 
 
 
-
 
NC_009832  Spro_1168  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  37.06 
 
 		 288 aa  164  2.0000000000000002e-39  Serratia proteamaculans 568  Bacteria  normal  0.0275067  normal  0.0260565 
 
 
-
 
NC_009049  Rsph17029_2314  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  37.76 
 
 		 296 aa  164  2.0000000000000002e-39  Rhodobacter sphaeroides ATCC 17029  Bacteria  normal  1  normal  0.206347 
 
 
-
 
NC_012793  GWCH70_2324  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  37.8 
 
 		 290 aa  164  2.0000000000000002e-39  Geobacillus sp. WCH70  Bacteria  hitchhiker  0.0000000808824  n/a   
 
 
-
 
NC_004116  SAG0494  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  35.95 
 
 		 284 aa  163  3e-39  Streptococcus agalactiae 2603V/R  Bacteria  normal  1  n/a   
 
 
-
 
NC_008044  TM1040_2356  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  37.04 
 
 		 300 aa  163  4.0000000000000004e-39  Ruegeria sp. TM1040  Bacteria  normal  1  normal  0.531119 
 
 
-
 
NC_009428  Rsph17025_0571  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  38.01 
 
 		 296 aa  163  4.0000000000000004e-39  Rhodobacter sphaeroides ATCC 17025  Bacteria  normal  1  normal  1 
 
 
-
 
NC_010814  Glov_0508  Methenyltetrahydrofolate cyclohydrolase  38.46 
 
 		 284 aa  162  5.0000000000000005e-39  Geobacter lovleyi SZ  Bacteria  decreased coverage  0.0000347177  n/a   
 
 
-
 
NC_007005  Psyr_2225  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  35.67 
 
 		 300 aa  162  5.0000000000000005e-39  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  0.0740597  normal  0.676073 
 
 
-
 
NC_009457  VC0395_A1533  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  38.6 
 
 		 311 aa  162  5.0000000000000005e-39  Vibrio cholerae O395  Bacteria  normal  1  n/a   
 
 
-
 
NC_013510  Tcur_4213  Methylenetetrahydrofolate dehydrogenase (NADP(+))  39.56 
 
 		 283 aa  162  5.0000000000000005e-39  Thermomonospora curvata DSM 43183  Bacteria  normal  1  n/a   
 
 
-
 
NC_009783  VIBHAR_01391  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  38.24 
 
 		 286 aa  162  6e-39  Vibrio harveyi ATCC BAA-1116  Bacteria  n/a    n/a   
 
 
-
 
NC_008340  Mlg_0591  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  35.03 
 
 		 286 aa  162  6e-39  Alkalilimnicola ehrlichii MLHE-1  Bacteria  hitchhiker  0.0000074286  unclonable  2.0108800000000004e-18 
 
 
-
 
NC_007493  RSP_0661  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  37.41 
 
 		 296 aa  162  9e-39  Rhodobacter sphaeroides 2.4.1  Bacteria  normal  1  n/a   
 
 
-
 
NC_009707  JJD26997_1004  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  35.84 
 
 		 282 aa  161  1e-38  Campylobacter jejuni subsp. doylei 269.97  Bacteria  normal  0.226194  n/a   
 
 
-
 
NC_008309  HS_1221  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  38.4 
 
 		 282 aa  161  1e-38  Haemophilus somnus 129PT  Bacteria  decreased coverage  0.00020406  n/a   
 
 
-
 
NC_013159  Svir_05000  methenyltetrahydrofolate cyclohydrolase /5,10-methylenetetrahydrofolate dehydrogenase (NADP+)  37.99 
 
 		 284 aa  160  2e-38  Saccharomonospora viridis DSM 43017  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009636  Smed_0290  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  37.1 
 
 		 299 aa  160  2e-38  Sinorhizobium medicae WSM419  Bacteria  normal  0.154774  normal  1 
 
 
-
 
NC_008009  Acid345_4424  methenyltetrahydrofolate cyclohydrolase  34.71 
 
 		 307 aa  161  2e-38  Candidatus Koribacter versatilis Ellin345  Bacteria  normal  1  normal  1 
 
 
-
 
NC_013595  Sros_1250  Methylenetetrahydrofolate dehydrogenase (NADP(+))  38.55 
 
 		 282 aa  160  2e-38  Streptosporangium roseum DSM 43021  Bacteria  normal  1  normal  0.0286426 
 
 
-
 
NC_007355  Mbar_A2315  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  37.31 
 
 		 287 aa  160  3e-38  Methanosarcina barkeri str. Fusaro  Archaea  normal  1  normal  1 
 
 
-
 
NC_007492  Pfl01_3699  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  36.18 
 
 		 284 aa  159  4e-38  Pseudomonas fluorescens Pf0-1  Bacteria  normal  1  normal  1 
 
 
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