More than 300 homologs were found in PanDaTox collection
for query gene TDE0013 on replicon NC_002967
Organism: Treponema denticola ATCC 35405



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Replicon accession
Locus tag
Product
% identity
Alignment on query gene
Alignment on homolog gene
Length
Bit score

E-value
Organism name
Kingdom
Plasmid clonability
Plasmid unclonability p-value
Fosmid clonability
Fosmid unclonability p-value
Coverage Plot
PanDaTox homologs
Experimental validation
NC_002967  TDE0013  methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase  100 
 
 		 293 aa  584  1e-166  Treponema denticola ATCC 35405  Bacteria  normal  1  n/a   
 
 
-
 
NC_013501  Rmar_0952  Methenyltetrahydrofolate cyclohydrolase  57.29 
 
 		 293 aa  342  5e-93  Rhodothermus marinus DSM 4252  Bacteria  normal  1  n/a   
 
 
-
 
NC_007514  Cag_0779  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  55.63 
 
 		 295 aa  333  2e-90  Chlorobium chlorochromatii CaD3  Bacteria  normal  1  n/a   
 
 
-
 
NC_008639  Cpha266_0997  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  56.8 
 
 		 308 aa  333  2e-90  Chlorobium phaeobacteroides DSM 266  Bacteria  normal  1  n/a   
 
 
-
 
NC_012034  Athe_0982  Methenyltetrahydrofolate cyclohydrolase  57.97 
 
 		 289 aa  330  1e-89  Anaerocellum thermophilum DSM 6725  Bacteria  hitchhiker  0.000669614  n/a   
 
 
-
 
NC_011059  Paes_1178  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  55.97 
 
 		 295 aa  328  9e-89  Prosthecochloris aestuarii DSM 271  Bacteria  normal  1  normal  0.545639 
 
 
-
 
NC_009455  DehaBAV1_0637  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  58.64 
 
 		 296 aa  326  3e-88  Dehalococcoides sp. BAV1  Bacteria  normal  1  n/a   
 
 
-
 
NC_013552  DhcVS_606  methylenetetrahydrofolate dehydrogenase (NADP+)/methenyltetrahydrofolate cyclohydrolase  58.31 
 
 		 296 aa  325  4.0000000000000003e-88  Dehalococcoides sp. VS  Bacteria  normal  1  n/a   
 
 
-
 
NC_005945  BAS4085  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  55.9 
 
 		 286 aa  325  4.0000000000000003e-88  Bacillus anthracis str. Sterne  Bacteria  hitchhiker  0.00334729  n/a   
 
 
-
 
NC_007530  GBAA_4405  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  55.9 
 
 		 286 aa  325  4.0000000000000003e-88  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  1  n/a   
 
 
-
 
NC_002936  DET0668  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  58.31 
 
 		 296 aa  325  5e-88  Dehalococcoides ethenogenes 195  Bacteria  normal  1  n/a   
 
 
-
 
NC_002936  DET0702  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  58.31 
 
 		 296 aa  325  5e-88  Dehalococcoides ethenogenes 195  Bacteria  normal  1  n/a   
 
 
-
 
NC_011725  BCB4264_A4291  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  55.9 
 
 		 286 aa  325  6e-88  Bacillus cereus B4264  Bacteria  normal  1  n/a   
 
 
-
 
NC_012793  GWCH70_2324  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  55.36 
 
 		 290 aa  325  6e-88  Geobacillus sp. WCH70  Bacteria  hitchhiker  0.0000000808824  n/a   
 
 
-
 
NC_011772  BCG9842_B0943  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  55.9 
 
 		 286 aa  324  1e-87  Bacillus cereus G9842  Bacteria  normal  1  hitchhiker  0.00348961 
 
 
-
 
NC_011773  BCAH820_4201  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  55.56 
 
 		 286 aa  323  2e-87  Bacillus cereus AH820  Bacteria  n/a    hitchhiker  3.73931e-16 
 
 
-
 
NC_005957  BT9727_3923  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  55.56 
 
 		 286 aa  323  2e-87  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  1  n/a   
 
 
-
 
NC_006274  BCZK3934  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  55.56 
 
 		 286 aa  323  2e-87  Bacillus cereus E33L  Bacteria  normal  0.0428362  n/a   
 
 
-
 
NC_010655  Amuc_1641  Methenyltetrahydrofolate cyclohydrolase  53.29 
 
 		 291 aa  323  2e-87  Akkermansia muciniphila ATCC BAA-835  Bacteria  normal  1  normal  0.794405 
 
 
-
 
NC_007512  Plut_0927  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  54.61 
 
 		 307 aa  323  2e-87  Chlorobium luteolum DSM 273  Bacteria  normal  1  normal  1 
 
 
-
 
NC_007644  Moth_1516  methenyltetrahydrofolate cyclohydrolase  56.25 
 
 		 280 aa  323  2e-87  Moorella thermoacetica ATCC 39073  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009674  Bcer98_2874  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  55.56 
 
 		 286 aa  323  2e-87  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  0.126852  n/a   
 
 
-
 
NC_011658  BCAH187_A4311  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  55.56 
 
 		 286 aa  323  2e-87  Bacillus cereus AH187  Bacteria  normal  0.0277859  n/a   
 
 
-
 
NC_003909  BCE_4254  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  55.21 
 
 		 286 aa  323  3e-87  Bacillus cereus ATCC 10987  Bacteria  normal  0.246013  n/a   
 
 
-
 
NC_007517  Gmet_1162  methenyltetrahydrofolate cyclohydrolase  56.99 
 
 		 285 aa  322  7e-87  Geobacter metallireducens GS-15  Bacteria  hitchhiker  0.00000000377219  hitchhiker  0.00798692 
 
 
-
 
NC_010184  BcerKBAB4_4033  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  55.56 
 
 		 286 aa  321  9.999999999999999e-87  Bacillus weihenstephanensis KBAB4  Bacteria  normal  0.781388  n/a   
 
 
-
 
NC_009012  Cthe_1093  methenyltetrahydrofolate cyclohydrolase  55.02 
 
 		 285 aa  321  9.999999999999999e-87  Clostridium thermocellum ATCC 27405  Bacteria  hitchhiker  0.000000512009  n/a   
 
 
-
 
NC_010831  Cphamn1_1442  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  53.74 
 
 		 298 aa  318  6e-86  Chlorobium phaeobacteroides BS1  Bacteria  normal  0.56836  normal  1 
 
 
-
 
NC_011662  Tmz1t_3190  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  55.9 
 
 		 295 aa  318  7e-86  Thauera sp. MZ1T  Bacteria  normal  0.905813  n/a   
 
 
-
 
NC_010803  Clim_1112  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  54.76 
 
 		 296 aa  317  1e-85  Chlorobium limicola DSM 245  Bacteria  normal  1  n/a   
 
 
-
 
NC_009483  Gura_1169  methylenetetrahydrofolate dehydrogenase (NADP(+))  56.45 
 
 		 280 aa  315  7e-85  Geobacter uraniireducens Rf4  Bacteria  hitchhiker  0.00000103166  n/a   
 
 
-
 
NC_011060  Ppha_1205  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  54.27 
 
 		 295 aa  315  7e-85  Pelodictyon phaeoclathratiforme BU-1  Bacteria  normal  1  n/a   
 
 
-
 
NC_009802  CCC13826_0832  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  56.29 
 
 		 283 aa  314  9e-85  Campylobacter concisus 13826  Bacteria  normal  0.048214  n/a   
 
 
-
 
NC_014148  Plim_3436  Methylenetetrahydrofolate dehydrogenase (NADP(+))  57.68 
 
 		 291 aa  313  9.999999999999999e-85  Planctomyces limnophilus DSM 3776  Bacteria  normal  1  n/a   
 
 
-
 
NC_011898  Ccel_0604  tetrahydrofolate dehydrogenase/cyclohydrolase  53.77 
 
 		 284 aa  309  4e-83  Clostridium cellulolyticum H10  Bacteria  normal  1  n/a   
 
 
-
 
NC_014230  CA2559_05920  putative methenyltetrahydrofolate cyclohydrolase  52.92 
 
 		 294 aa  308  6.999999999999999e-83  Croceibacter atlanticus HTCC2559  Bacteria  normal  0.298179  n/a   
 
 
-
 
NC_012918  GM21_2719  Methylenetetrahydrofolate dehydrogenase (NADP(+))  55.59 
 
 		 281 aa  308  9e-83  Geobacter sp. M21  Bacteria  n/a    normal  1 
 
 
-
 
NC_010718  Nther_1700  5,10-methylenetetrahydrofolate dehydrogenase (NADP+), Methenyltetrahydrofolate cyclohydrolase  53.47 
 
 		 284 aa  308  9e-83  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  1  normal  0.335496 
 
 
-
 
NC_011146  Gbem_1497  tetrahydrofolate dehydrogenase/cyclohydrolase  55.24 
 
 		 281 aa  306  2.0000000000000002e-82  Geobacter bemidjiensis Bem  Bacteria  hitchhiker  0.0000244416  n/a   
 
 
-
 
NC_009715  CCV52592_0799  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  52.8 
 
 		 288 aa  306  4.0000000000000004e-82  Campylobacter curvus 525.92  Bacteria  normal  1  n/a   
 
 
-
 
NC_002939  GSU0862  folD bifunctional protein  55.79 
 
 		 285 aa  301  1e-80  Geobacter sulfurreducens PCA  Bacteria  normal  1  n/a   
 
 
-
 
NC_010424  Daud_0103  methenyltetrahydrofolate cyclohydrolase  51.37 
 
 		 294 aa  300  1e-80  Candidatus Desulforudis audaxviator MP104C  Bacteria  normal  1  n/a   
 
 
-
 
NC_010814  Glov_0508  Methenyltetrahydrofolate cyclohydrolase  54.51 
 
 		 284 aa  299  3e-80  Geobacter lovleyi SZ  Bacteria  decreased coverage  0.0000347177  n/a   
 
 
-
 
NC_009441  Fjoh_0243  methenyltetrahydrofolate cyclohydrolase  51.03 
 
 		 295 aa  299  3e-80  Flavobacterium johnsoniae UW101  Bacteria  normal  0.424565  n/a   
 
 
-
 
NC_007298  Daro_0448  methenyltetrahydrofolate cyclohydrolase  54.11 
 
 		 284 aa  299  4e-80  Dechloromonas aromatica RCB  Bacteria  normal  0.326868  normal  0.769812 
 
 
-
 
NC_008686  Pden_2614  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  53.92 
 
 		 298 aa  298  6e-80  Paracoccus denitrificans PD1222  Bacteria  normal  0.508138  normal  1 
 
 
-
 
NC_008255  CHU_1716  methenyltetrahydrofolate cyclohydrolase  52.8 
 
 		 290 aa  298  6e-80  Cytophaga hutchinsonii ATCC 33406  Bacteria  normal  0.0294463  normal  1 
 
 
-
 
NC_007005  Psyr_2225  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  52.94 
 
 		 300 aa  298  8e-80  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  0.0740597  normal  0.676073 
 
 
-
 
NC_008527  LACR_0921  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  53.68 
 
 		 295 aa  298  9e-80  Lactococcus lactis subsp. cremoris SK11  Bacteria  unclonable  0.0000659615  n/a   
 
 
-
 
NC_009439  Pmen_3458  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  52.41 
 
 		 303 aa  296  4e-79  Pseudomonas mendocina ymp  Bacteria  normal  1  normal  1 
 
 
-
 
NC_008340  Mlg_0591  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  52.23 
 
 		 286 aa  295  6e-79  Alkalilimnicola ehrlichii MLHE-1  Bacteria  hitchhiker  0.0000074286  unclonable  2.0108800000000004e-18 
 
 
-
 
NC_009714  CHAB381_1036  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  51.4 
 
 		 284 aa  295  7e-79  Campylobacter hominis ATCC BAA-381  Bacteria  normal  1  n/a   
 
 
-
 
NC_008688  Pden_4905  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  53.98 
 
 		 302 aa  295  7e-79  Paracoccus denitrificans PD1222  Bacteria  normal  1  normal  0.171078 
 
 
-
 
NC_011899  Hore_06480  tetrahydrofolate dehydrogenase/cyclohydrolase  53.08 
 
 		 283 aa  295  8e-79  Halothermothrix orenii H 168  Bacteria  hitchhiker  0.000000303472  n/a   
 
 
-
 
NC_011883  Ddes_2215  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  52.6 
 
 		 285 aa  293  2e-78  Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774  Bacteria  normal  1  n/a   
 
 
-
 
NC_008576  Mmc1_3712  methenyltetrahydrofolate cyclohydrolase  52.58 
 
 		 285 aa  293  2e-78  Magnetococcus sp. MC-1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_013411  GYMC61_0247  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  51.39 
 
 		 284 aa  293  3e-78  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_009632  SaurJH1_1145  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  48.81 
 
 		 286 aa  292  4e-78  Staphylococcus aureus subsp. aureus JH1  Bacteria  hitchhiker  0.00105319  n/a   
 
 
-
 
NC_013162  Coch_1786  Methenyltetrahydrofolate cyclohydrolase  51.4 
 
 		 291 aa  292  4e-78  Capnocytophaga ochracea DSM 7271  Bacteria  normal  0.431166  n/a   
 
 
-
 
NC_009487  SaurJH9_1123  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  48.81 
 
 		 286 aa  292  4e-78  Staphylococcus aureus subsp. aureus JH9  Bacteria  hitchhiker  0.000919852  n/a   
 
 
-
 
NC_008554  Sfum_2686  methylenetetrahydrofolate dehydrogenase (NADP(+))  51.02 
 
 		 295 aa  292  6e-78  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  0.204372  normal  0.0139654 
 
 
-
 
NC_008609  Ppro_0480  methenyltetrahydrofolate cyclohydrolase  54.9 
 
 		 283 aa  291  8e-78  Pelobacter propionicus DSM 2379  Bacteria  hitchhiker  0.00000146162  n/a   
 
 
-
 
NC_008599  CFF8240_1174  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  53.15 
 
 		 283 aa  291  9e-78  Campylobacter fetus subsp. fetus 82-40  Bacteria  normal  0.840508  n/a   
 
 
-
 
NC_004116  SAG0494  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  50 
 
 		 284 aa  290  2e-77  Streptococcus agalactiae 2603V/R  Bacteria  normal  1  n/a   
 
 
-
 
NC_013132  Cpin_6931  Methenyltetrahydrofolate cyclohydrolase  51.9 
 
 		 294 aa  290  2e-77  Chitinophaga pinensis DSM 2588  Bacteria  normal  1  normal  0.650439 
 
 
-
 
NC_010730  SYO3AOP1_1067  Methenyltetrahydrofolate cyclohydrolase  52.96 
 
 		 285 aa  290  2e-77  Sulfurihydrogenibium sp. YO3AOP1  Bacteria  normal  1  n/a   
 
 
-
 
NC_009439  Pmen_3471  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  51.92 
 
 		 307 aa  290  2e-77  Pseudomonas mendocina ymp  Bacteria  normal  1  normal  1 
 
 
-
 
NC_008751  Dvul_2658  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  51.03 
 
 		 286 aa  289  4e-77  Desulfovibrio vulgaris DP4  Bacteria  normal  0.51858  normal  1 
 
 
-
 
NC_009368  OSTLU_27405  predicted protein  51.56 
 
 		 300 aa  288  8e-77  Ostreococcus lucimarinus CCE9901  Eukaryota  normal  1  normal  0.179734 
 
 
-
 
NC_007794  Saro_3300  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  51.02 
 
 		 297 aa  287  1e-76  Novosphingobium aromaticivorans DSM 12444  Bacteria  normal  1  n/a   
 
 
-
 
NC_009049  Rsph17029_2314  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  52.56 
 
 		 296 aa  286  2e-76  Rhodobacter sphaeroides ATCC 17029  Bacteria  normal  1  normal  0.206347 
 
 
-
 
NC_002950  PG1116  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  48.44 
 
 		 296 aa  286  2e-76  Porphyromonas gingivalis W83  Bacteria  n/a    normal  0.991607 
 
 
-
 
NC_010571  Oter_3793  methenyltetrahydrofolate cyclohydrolase  51.38 
 
 		 293 aa  286  2.9999999999999996e-76  Opitutus terrae PB90-1  Bacteria  normal  0.0648  normal  0.492726 
 
 
-
 
NC_010322  PputGB1_2105  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  52.94 
 
 		 303 aa  286  2.9999999999999996e-76  Pseudomonas putida GB-1  Bacteria  normal  0.538628  normal  0.603824 
 
 
-
 
NC_007493  RSP_0661  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  52.56 
 
 		 296 aa  286  2.9999999999999996e-76  Rhodobacter sphaeroides 2.4.1  Bacteria  normal  1  n/a   
 
 
-
 
NC_009428  Rsph17025_0571  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  53.58 
 
 		 296 aa  286  2.9999999999999996e-76  Rhodobacter sphaeroides ATCC 17025  Bacteria  normal  1  normal  1 
 
 
-
 
NC_008044  TM1040_2356  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  52.04 
 
 		 300 aa  286  4e-76  Ruegeria sp. TM1040  Bacteria  normal  1  normal  0.531119 
 
 
-
 
NC_009719  Plav_1372  methenyltetrahydrofolate cyclohydrolase  50.34 
 
 		 298 aa  286  4e-76  Parvibaculum lavamentivorans DS-1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_004311  BRA0781  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  52.7 
 
 		 299 aa  285  7e-76  Brucella suis 1330  Bacteria  normal  1  n/a   
 
 
-
 
NC_009504  BOV_A0731  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  52.7 
 
 		 299 aa  285  7e-76  Brucella ovis ATCC 25840  Bacteria  normal  1  n/a   
 
 
-
 
NC_009720  Xaut_4086  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  54.67 
 
 		 295 aa  285  7e-76  Xanthobacter autotrophicus Py2  Bacteria  normal  1  normal  1 
 
 
-
 
NC_007520  Tcr_0723  methylenetetrahydrofolate dehydrogenase (NADP+)  53.31 
 
 		 309 aa  285  9e-76  Thiomicrospira crunogena XCL-2  Bacteria  hitchhiker  0.00000000206547  n/a   
 
 
-
 
NC_008740  Maqu_1842  methylenetetrahydrofolate dehydrogenase (NADP(+))  53.66 
 
 		 304 aa  285  9e-76  Marinobacter aquaeolei VT8  Bacteria  normal  0.0144811  n/a   
 
 
-
 
NC_013158  Huta_2943  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  50.51 
 
 		 297 aa  285  9e-76  Halorhabdus utahensis DSM 12940  Archaea  normal  0.420051  n/a   
 
 
-
 
NC_008781  Pnap_1778  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  48.96 
 
 		 281 aa  284  1.0000000000000001e-75  Polaromonas naphthalenivorans CJ2  Bacteria  normal  1  normal  0.0122285 
 
 
-
 
NC_007519  Dde_0296  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  50.86 
 
 		 286 aa  284  1.0000000000000001e-75  Desulfovibrio desulfuricans subsp. desulfuricans str. G20  Bacteria  normal  1  n/a   
 
 
-
 
NC_009668  Oant_3959  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  52.36 
 
 		 299 aa  284  1.0000000000000001e-75  Ochrobactrum anthropi ATCC 49188  Bacteria  normal  0.791035  n/a   
 
 
-
 
NC_007614  Nmul_A0357  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  51.03 
 
 		 288 aa  283  2.0000000000000002e-75  Nitrosospira multiformis ATCC 25196  Bacteria  normal  0.991729  n/a   
 
 
-
 
NC_008825  Mpe_A2131  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  50.86 
 
 		 283 aa  283  2.0000000000000002e-75  Methylibium petroleiphilum PM1  Bacteria  normal  0.386646  normal  1 
 
 
-
 
NC_008752  Aave_2459  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  50.17 
 
 		 283 aa  283  3.0000000000000004e-75  Acidovorax citrulli AAC00-1  Bacteria  normal  0.0798593  normal  1 
 
 
-
 
NC_013730  Slin_1575  Methenyltetrahydrofolate cyclohydrolase  49.48 
 
 		 295 aa  283  3.0000000000000004e-75  Spirosoma linguale DSM 74  Bacteria  normal  0.251532  normal  0.0116003 
 
 
-
 
NC_002976  SERP0648  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  48.97 
 
 		 286 aa  282  4.0000000000000003e-75  Staphylococcus epidermidis RP62A  Bacteria  normal  1  n/a   
 
 
-
 
NC_013037  Dfer_1212  Methenyltetrahydrofolate cyclohydrolase  47.4 
 
 		 293 aa  282  5.000000000000001e-75  Dyadobacter fermentans DSM 18053  Bacteria  decreased coverage  0.000340013  decreased coverage  0.0000458774 
 
 
-
 
NC_013173  Dbac_3223  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  51.74 
 
 		 281 aa  282  6.000000000000001e-75  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  1  n/a   
 
 
-
 
NC_012039  Cla_0581  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  49.3 
 
 		 298 aa  281  7.000000000000001e-75  Campylobacter lari RM2100  Bacteria  normal  0.388564  n/a   
 
 
-
 
NC_004578  PSPTO_2453  methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase  51.21 
 
 		 300 aa  281  8.000000000000001e-75  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  0.0165644  n/a   
 
 
-
 
NC_013922  Nmag_2300  Methenyltetrahydrofolate cyclohydrolase  51.03 
 
 		 297 aa  281  1e-74  Natrialba magadii ATCC 43099  Archaea  normal  1  n/a   
 
 
-
 
NC_013202  Hmuk_2214  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  48.63 
 
 		 297 aa  280  2e-74  Halomicrobium mukohataei DSM 12286  Archaea  normal  0.621742  normal  0.605059 
 
 
-
 
NC_012029  Hlac_1624  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  51.21 
 
 		 307 aa  280  2e-74  Halorubrum lacusprofundi ATCC 49239  Archaea  normal  1  normal  1 
 
 
-
 
NC_010581  Bind_0805  methenyltetrahydrofolate cyclohydrolase  50.83 
 
 		 320 aa  280  3e-74  Beijerinckia indica subsp. indica ATCC 9039  Bacteria  normal  1  normal  1 
 
 
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