More than 300 homologs were found in PanDaTox collection
for query gene Svir_05000 on replicon NC_013159
Organism: Saccharomonospora viridis DSM 43017



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Replicon accession
Locus tag
Product
% identity
Alignment on query gene
Alignment on homolog gene
Length
Bit score

E-value
Organism name
Kingdom
Plasmid clonability
Plasmid unclonability p-value
Fosmid clonability
Fosmid unclonability p-value
Coverage Plot
PanDaTox homologs
Experimental validation
NC_013159  Svir_05000  methenyltetrahydrofolate cyclohydrolase /5,10-methylenetetrahydrofolate dehydrogenase (NADP+)  100 
 
 		 284 aa  560  1.0000000000000001e-159  Saccharomonospora viridis DSM 43017  Bacteria  normal  1  normal  1 
 
 
-
 
NC_014158  Tpau_0941  Methylenetetrahydrofolate dehydrogenase (NADP(+))  73.59 
 
 		 294 aa  416  9.999999999999999e-116  Tsukamurella paurometabola DSM 20162  Bacteria  normal  1  n/a   
 
 
-
 
NC_008705  Mkms_1221  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  71.63 
 
 		 288 aa  402  1e-111  Mycobacterium sp. KMS  Bacteria  normal  0.0946593  normal  1 
 
 
-
 
NC_009077  Mjls_1231  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  71.63 
 
 		 288 aa  402  1e-111  Mycobacterium sp. JLS  Bacteria  normal  0.60166  normal  0.154902 
 
 
-
 
NC_014165  Tbis_0661  methylenetetrahydrofolate dehydrogenase (NADP(+))  71.07 
 
 		 284 aa  397  1e-109  Thermobispora bispora DSM 43833  Bacteria  normal  0.839068  normal  0.303542 
 
 
-
 
NC_013510  Tcur_4213  Methylenetetrahydrofolate dehydrogenase (NADP(+))  74.17 
 
 		 283 aa  395  1e-109  Thermomonospora curvata DSM 43183  Bacteria  normal  1  n/a   
 
 
-
 
NC_008726  Mvan_1550  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  70.5 
 
 		 288 aa  393  1e-108  Mycobacterium vanbaalenii PYR-1  Bacteria  normal  1  normal  0.103372 
 
 
-
 
NC_008578  Acel_0385  methenyltetrahydrofolate cyclohydrolase  71.23 
 
 		 293 aa  388  1e-107  Acidothermus cellulolyticus 11B  Bacteria  normal  1  normal  1 
 
 
-
 
NC_013093  Amir_6498  Methenyltetrahydrofolate cyclohydrolase  73.93 
 
 		 288 aa  387  1e-106  Actinosynnema mirum DSM 43827  Bacteria  normal  1  n/a   
 
 
-
 
NC_009338  Mflv_4879  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  70.14 
 
 		 286 aa  385  1e-106  Mycobacterium gilvum PYR-GCK  Bacteria  normal  1  normal  0.0903189 
 
 
-
 
NC_009565  TBFG_13392  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  68.57 
 
 		 281 aa  385  1e-106  Mycobacterium tuberculosis F11  Bacteria  normal  1  normal  0.0406677 
 
 
-
 
NC_013595  Sros_1250  Methylenetetrahydrofolate dehydrogenase (NADP(+))  69.64 
 
 		 282 aa  381  1e-105  Streptosporangium roseum DSM 43021  Bacteria  normal  1  normal  0.0286426 
 
 
-
 
NC_013441  Gbro_1757  Methylenetetrahydrofolate dehydrogenase (NADP(+))  67.5 
 
 		 300 aa  377  1e-103  Gordonia bronchialis DSM 43247  Bacteria  normal  0.985055  n/a   
 
 
-
 
NC_013757  Gobs_4416  Methylenetetrahydrofolate dehydrogenase (NADP(+))  72 
 
 		 289 aa  375  1e-103  Geodermatophilus obscurus DSM 43160  Bacteria  normal  1  n/a   
 
 
-
 
NC_007333  Tfu_2571  methenyltetrahydrofolate cyclohydrolase  70.92 
 
 		 283 aa  369  1e-101  Thermobifida fusca YX  Bacteria  normal  1  n/a   
 
 
-
 
NC_014210  Ndas_3963  Methenyltetrahydrofolate cyclohydrolase  70 
 
 		 285 aa  364  1e-99  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009953  Sare_4175  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  67.37 
 
 		 286 aa  362  3e-99  Salinispora arenicola CNS-205  Bacteria  normal  0.643036  hitchhiker  0.00167554 
 
 
-
 
NC_013131  Caci_7979  Methenyltetrahydrofolate cyclohydrolase  65.71 
 
 		 282 aa  362  5.0000000000000005e-99  Catenulispora acidiphila DSM 44928  Bacteria  normal  0.733694  normal  1 
 
 
-
 
NC_009380  Strop_3795  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  65.96 
 
 		 286 aa  355  3.9999999999999996e-97  Salinispora tropica CNB-440  Bacteria  normal  0.335106  normal  1 
 
 
-
 
NC_008146  Mmcs_1204  methenyltetrahydrofolate cyclohydrolase  71.66 
 
 		 248 aa  353  2e-96  Mycobacterium sp. MCS  Bacteria  normal  0.176488  n/a   
 
 
-
 
NC_013169  Ksed_07820  methenyltetrahydrofolate cyclohydrolase /5,10-methylenetetrahydrofolate dehydrogenase (NADP+)  64.29 
 
 		 282 aa  349  3e-95  Kytococcus sedentarius DSM 20547  Bacteria  normal  0.474597  normal  0.925749 
 
 
-
 
NC_008699  Noca_3582  methenyltetrahydrofolate cyclohydrolase  69.4 
 
 		 283 aa  345  4e-94  Nocardioides sp. JS614  Bacteria  normal  1  n/a   
 
 
-
 
NC_013235  Namu_1278  Methylenetetrahydrofolate dehydrogenase (NADP(+))  69.78 
 
 		 287 aa  343  2.9999999999999997e-93  Nakamurella multipartita DSM 44233  Bacteria  normal  0.233978  normal  0.555199 
 
 
-
 
NC_011886  Achl_1190  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  59.59 
 
 		 300 aa  338  4e-92  Arthrobacter chlorophenolicus A6  Bacteria  n/a    hitchhiker  0.000000347657 
 
 
-
 
NC_008541  Arth_1116  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  58.97 
 
 		 302 aa  335  5e-91  Arthrobacter sp. FB24  Bacteria  normal  0.100033  n/a   
 
 
-
 
NC_012803  Mlut_04690  methenyltetrahydrofolate cyclohydrolase /5,10-methylenetetrahydrofolate dehydrogenase (NADP+)  60.9 
 
 		 303 aa  334  7.999999999999999e-91  Micrococcus luteus NCTC 2665  Bacteria  normal  1  n/a   
 
 
-
 
NC_013172  Bfae_21360  methenyltetrahydrofolate cyclohydrolase /5,10-methylenetetrahydrofolate dehydrogenase (NADP+)  62.2 
 
 		 299 aa  325  5e-88  Brachybacterium faecium DSM 4810  Bacteria  normal  0.388828  n/a   
 
 
-
 
NC_014151  Cfla_2500  Methylenetetrahydrofolate dehydrogenase (NADP(+))  64.14 
 
 		 293 aa  320  9.999999999999999e-87  Cellulomonas flavigena DSM 20109  Bacteria  normal  1  normal  1 
 
 
-
 
NC_010816  BLD_0746  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  55.56 
 
 		 291 aa  316  4e-85  Bifidobacterium longum DJO10A  Bacteria  normal  0.0724319  n/a   
 
 
-
 
NC_013530  Xcel_0755  Methenyltetrahydrofolate cyclohydrolase  61.99 
 
 		 293 aa  315  7e-85  Xylanimonas cellulosilytica DSM 15894  Bacteria  normal  0.0513262  n/a   
 
 
-
 
NC_009664  Krad_3980  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  61.64 
 
 		 295 aa  310  1e-83  Kineococcus radiotolerans SRS30216  Bacteria  normal  1  normal  0.578436 
 
 
-
 
NC_013721  HMPREF0424_0600  tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein  53.85 
 
 		 294 aa  300  3e-80  Gardnerella vaginalis 409-05  Bacteria  n/a    normal  1 
 
 
-
 
NC_013174  Jden_0695  Methenyltetrahydrofolate cyclohydrolase  59.59 
 
 		 297 aa  296  2e-79  Jonesia denitrificans DSM 20603  Bacteria  normal  1  normal  1 
 
 
-
 
NC_013521  Sked_27930  methenyltetrahydrofolate cyclohydrolase /5,10-methylenetetrahydrofolate dehydrogenase (NADP+)  61.72 
 
 		 295 aa  295  4e-79  Sanguibacter keddieii DSM 10542  Bacteria  normal  0.772386  normal  1 
 
 
-
 
NC_008699  Noca_0641  methenyltetrahydrofolate cyclohydrolase  54.68 
 
 		 296 aa  287  1e-76  Nocardioides sp. JS614  Bacteria  normal  1  n/a   
 
 
-
 
NC_013124  Afer_0323  Methenyltetrahydrofolate cyclohydrolase  54.2 
 
 		 289 aa  275  8e-73  Acidimicrobium ferrooxidans DSM 10331  Bacteria  normal  0.044033  n/a   
 
 
-
 
NC_013739  Cwoe_3588  Methylenetetrahydrofolate dehydrogenase (NADP(+))  54.29 
 
 		 283 aa  274  1.0000000000000001e-72  Conexibacter woesei DSM 14684  Bacteria  normal  0.24704  normal  0.653023 
 
 
-
 
NC_007498  Pcar_2461  putative methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase  48.6 
 
 		 290 aa  267  1e-70  Pelobacter carbinolicus DSM 2380  Bacteria  unclonable  2.7031099999999997e-20  n/a   
 
 
-
 
NC_007644  Moth_1516  methenyltetrahydrofolate cyclohydrolase  50.71 
 
 		 280 aa  266  2.9999999999999995e-70  Moorella thermoacetica ATCC 39073  Bacteria  normal  1  normal  1 
 
 
-
 
NC_010718  Nther_1700  5,10-methylenetetrahydrofolate dehydrogenase (NADP+), Methenyltetrahydrofolate cyclohydrolase  47.02 
 
 		 284 aa  265  5.999999999999999e-70  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  1  normal  0.335496 
 
 
-
 
NC_013161  Cyan8802_1617  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  50.53 
 
 		 292 aa  262  4.999999999999999e-69  Cyanothece sp. PCC 8802  Bacteria  normal  1  normal  1 
 
 
-
 
NC_008312  Tery_4172  methenyltetrahydrofolate cyclohydrolase  46.4 
 
 		 287 aa  262  6e-69  Trichodesmium erythraeum IMS101  Bacteria  normal  1  normal  0.280923 
 
 
-
 
NC_011726  PCC8801_1592  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  50.18 
 
 		 292 aa  260  2e-68  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_011662  Tmz1t_3190  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  50 
 
 		 295 aa  259  3e-68  Thauera sp. MZ1T  Bacteria  normal  0.905813  n/a   
 
 
-
 
NC_011729  PCC7424_0607  Methenyltetrahydrofolate cyclohydrolase  48.57 
 
 		 301 aa  259  3e-68  Cyanothece sp. PCC 7424  Bacteria  n/a    normal  1 
 
 
-
 
NC_007413  Ava_2703  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  47.93 
 
 		 299 aa  259  4e-68  Anabaena variabilis ATCC 29413  Bacteria  hitchhiker  0.00240961  normal  0.676317 
 
 
-
 
NC_011883  Ddes_2215  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  51.07 
 
 		 285 aa  258  9e-68  Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774  Bacteria  normal  1  n/a   
 
 
-
 
NC_011884  Cyan7425_0973  Methylenetetrahydrofolate dehydrogenase (NADP(+))  48.75 
 
 		 293 aa  257  1e-67  Cyanothece sp. PCC 7425  Bacteria  normal  0.150063  normal  0.215441 
 
 
-
 
NC_007908  Rfer_2209  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  48.4 
 
 		 287 aa  257  1e-67  Rhodoferax ferrireducens T118  Bacteria  normal  0.699057  n/a   
 
 
-
 
NC_002939  GSU0862  folD bifunctional protein  50.54 
 
 		 285 aa  257  2e-67  Geobacter sulfurreducens PCA  Bacteria  normal  1  n/a   
 
 
-
 
NC_007517  Gmet_1162  methenyltetrahydrofolate cyclohydrolase  46.98 
 
 		 285 aa  256  2e-67  Geobacter metallireducens GS-15  Bacteria  hitchhiker  0.00000000377219  hitchhiker  0.00798692 
 
 
-
 
NC_012918  GM21_2719  Methylenetetrahydrofolate dehydrogenase (NADP(+))  49.29 
 
 		 281 aa  256  3e-67  Geobacter sp. M21  Bacteria  n/a    normal  1 
 
 
-
 
NC_011725  BCB4264_A4291  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  46.45 
 
 		 286 aa  256  4e-67  Bacillus cereus B4264  Bacteria  normal  1  n/a   
 
 
-
 
NC_007347  Reut_A1299  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  49.65 
 
 		 283 aa  256  4e-67  Ralstonia eutropha JMP134  Bacteria  normal  0.293991  n/a   
 
 
-
 
NC_011992  Dtpsy_1654  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  48.41 
 
 		 282 aa  256  4e-67  Acidovorax ebreus TPSY  Bacteria  normal  1  n/a   
 
 
-
 
NC_014248  Aazo_1506  methenyltetrahydrofolate cyclohydrolase  49.12 
 
 		 294 aa  255  5e-67  'Nostoc azollae' 0708  Bacteria  normal  1  n/a   
 
 
-
 
NC_009483  Gura_1169  methylenetetrahydrofolate dehydrogenase (NADP(+))  48.93 
 
 		 280 aa  255  6e-67  Geobacter uraniireducens Rf4  Bacteria  hitchhiker  0.00000103166  n/a   
 
 
-
 
NC_011772  BCG9842_B0943  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  46.45 
 
 		 286 aa  255  6e-67  Bacillus cereus G9842  Bacteria  normal  1  hitchhiker  0.00348961 
 
 
-
 
NC_013743  Htur_1699  Methenyltetrahydrofolate cyclohydrolase  50.17 
 
 		 297 aa  255  7e-67  Haloterrigena turkmenica DSM 5511  Archaea  n/a    n/a   
 
 
-
 
NC_008782  Ajs_2128  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  48.06 
 
 		 282 aa  254  8e-67  Acidovorax sp. JS42  Bacteria  normal  1  normal  0.616371 
 
 
-
 
NC_011658  BCAH187_A4311  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  45.74 
 
 		 286 aa  254  9e-67  Bacillus cereus AH187  Bacteria  normal  0.0277859  n/a   
 
 
-
 
NC_011146  Gbem_1497  tetrahydrofolate dehydrogenase/cyclohydrolase  48.57 
 
 		 281 aa  254  9e-67  Geobacter bemidjiensis Bem  Bacteria  hitchhiker  0.0000244416  n/a   
 
 
-
 
NC_010184  BcerKBAB4_4033  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  45.74 
 
 		 286 aa  254  1.0000000000000001e-66  Bacillus weihenstephanensis KBAB4  Bacteria  normal  0.781388  n/a   
 
 
-
 
NC_003909  BCE_4254  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  45.74 
 
 		 286 aa  254  2.0000000000000002e-66  Bacillus cereus ATCC 10987  Bacteria  normal  0.246013  n/a   
 
 
-
 
NC_005957  BT9727_3923  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  45.39 
 
 		 286 aa  253  3e-66  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  1  n/a   
 
 
-
 
NC_011899  Hore_06480  tetrahydrofolate dehydrogenase/cyclohydrolase  49.28 
 
 		 283 aa  253  3e-66  Halothermothrix orenii H 168  Bacteria  hitchhiker  0.000000303472  n/a   
 
 
-
 
NC_011773  BCAH820_4201  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  45.39 
 
 		 286 aa  253  3e-66  Bacillus cereus AH820  Bacteria  n/a    hitchhiker  3.73931e-16 
 
 
-
 
NC_009674  Bcer98_2874  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  44.33 
 
 		 286 aa  252  5.000000000000001e-66  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  0.126852  n/a   
 
 
-
 
NC_012791  Vapar_2159  Methylenetetrahydrofolate dehydrogenase (NADP(+))  46.67 
 
 		 283 aa  252  6e-66  Variovorax paradoxus S110  Bacteria  normal  0.639508  n/a   
 
 
-
 
NC_010002  Daci_3983  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  47.7 
 
 		 284 aa  252  6e-66  Delftia acidovorans SPH-1  Bacteria  normal  0.763661  normal  0.0287042 
 
 
-
 
NC_008554  Sfum_2686  methylenetetrahydrofolate dehydrogenase (NADP(+))  45.33 
 
 		 295 aa  251  7e-66  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  0.204372  normal  0.0139654 
 
 
-
 
NC_006274  BCZK3934  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  45.04 
 
 		 286 aa  251  8.000000000000001e-66  Bacillus cereus E33L  Bacteria  normal  0.0428362  n/a   
 
 
-
 
NC_012793  GWCH70_2324  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  46.15 
 
 		 290 aa  251  8.000000000000001e-66  Geobacillus sp. WCH70  Bacteria  hitchhiker  0.0000000808824  n/a   
 
 
-
 
NC_013162  Coch_1786  Methenyltetrahydrofolate cyclohydrolase  47.39 
 
 		 291 aa  251  9.000000000000001e-66  Capnocytophaga ochracea DSM 7271  Bacteria  normal  0.431166  n/a   
 
 
-
 
NC_005945  BAS4085  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  45.04 
 
 		 286 aa  251  1e-65  Bacillus anthracis str. Sterne  Bacteria  hitchhiker  0.00334729  n/a   
 
 
-
 
NC_007530  GBAA_4405  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  45.04 
 
 		 286 aa  251  1e-65  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  1  n/a   
 
 
-
 
NC_008009  Acid345_4424  methenyltetrahydrofolate cyclohydrolase  46.36 
 
 		 307 aa  251  1e-65  Candidatus Koribacter versatilis Ellin345  Bacteria  normal  1  normal  1 
 
 
-
 
NC_008148  Rxyl_0827  methenyltetrahydrofolate cyclohydrolase  51.8 
 
 		 284 aa  251  1e-65  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  0.997708  n/a   
 
 
-
 
NC_010814  Glov_0508  Methenyltetrahydrofolate cyclohydrolase  47.55 
 
 		 284 aa  251  1e-65  Geobacter lovleyi SZ  Bacteria  decreased coverage  0.0000347177  n/a   
 
 
-
 
NC_008025  Dgeo_0699  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  51.23 
 
 		 289 aa  250  2e-65  Deinococcus geothermalis DSM 11300  Bacteria  normal  0.09451  normal  1 
 
 
-
 
NC_008340  Mlg_0591  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  46.81 
 
 		 286 aa  250  2e-65  Alkalilimnicola ehrlichii MLHE-1  Bacteria  hitchhiker  0.0000074286  unclonable  2.0108800000000004e-18 
 
 
-
 
NC_008781  Pnap_1778  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  47.16 
 
 		 281 aa  249  3e-65  Polaromonas naphthalenivorans CJ2  Bacteria  normal  1  normal  0.0122285 
 
 
-
 
NC_008825  Mpe_A2131  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  46.83 
 
 		 283 aa  249  3e-65  Methylibium petroleiphilum PM1  Bacteria  normal  0.386646  normal  1 
 
 
-
 
NC_008752  Aave_2459  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  47.87 
 
 		 283 aa  249  4e-65  Acidovorax citrulli AAC00-1  Bacteria  normal  0.0798593  normal  1 
 
 
-
 
NC_012034  Athe_0982  Methenyltetrahydrofolate cyclohydrolase  47.18 
 
 		 289 aa  249  4e-65  Anaerocellum thermophilum DSM 6725  Bacteria  hitchhiker  0.000669614  n/a   
 
 
-
 
NC_012039  Cla_0581  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  44.17 
 
 		 298 aa  248  7e-65  Campylobacter lari RM2100  Bacteria  normal  0.388564  n/a   
 
 
-
 
NC_007796  Mhun_0022  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  50.79 
 
 		 279 aa  248  9e-65  Methanospirillum hungatei JF-1  Archaea  normal  1  normal  1 
 
 
-
 
NC_009656  PSPA7_3507  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  49.12 
 
 		 284 aa  248  9e-65  Pseudomonas aeruginosa PA7  Bacteria  normal  1  n/a   
 
 
-
 
NC_002967  TDE0013  methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase  45.49 
 
 		 293 aa  248  1e-64  Treponema denticola ATCC 35405  Bacteria  normal  1  n/a   
 
 
-
 
NC_013922  Nmag_2300  Methenyltetrahydrofolate cyclohydrolase  49.12 
 
 		 297 aa  247  1e-64  Natrialba magadii ATCC 43099  Archaea  normal  1  n/a   
 
 
-
 
NC_013422  Hneap_0646  Methylenetetrahydrofolate dehydrogenase (NADP(+))  48.42 
 
 		 286 aa  247  1e-64  Halothiobacillus neapolitanus c2  Bacteria  normal  1  n/a   
 
 
-
 
NC_013501  Rmar_0952  Methenyltetrahydrofolate cyclohydrolase  49.48 
 
 		 293 aa  246  2e-64  Rhodothermus marinus DSM 4252  Bacteria  normal  1  n/a   
 
 
-
 
NC_009712  Mboo_2188  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  47.83 
 
 		 278 aa  246  3e-64  Candidatus Methanoregula boonei 6A8  Archaea  normal  0.590033  normal  1 
 
 
-
 
NC_011898  Ccel_0604  tetrahydrofolate dehydrogenase/cyclohydrolase  44.8 
 
 		 284 aa  246  3e-64  Clostridium cellulolyticum H10  Bacteria  normal  1  n/a   
 
 
-
 
NC_007298  Daro_0448  methenyltetrahydrofolate cyclohydrolase  46.45 
 
 		 284 aa  246  4e-64  Dechloromonas aromatica RCB  Bacteria  normal  0.326868  normal  0.769812 
 
 
-
 
NC_009439  Pmen_2048  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  47.7 
 
 		 284 aa  245  4.9999999999999997e-64  Pseudomonas mendocina ymp  Bacteria  normal  0.629007  normal  0.184517 
 
 
-
 
NC_013173  Dbac_3223  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  49.45 
 
 		 281 aa  246  4.9999999999999997e-64  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  1  n/a   
 
 
-
 
NC_009012  Cthe_1093  methenyltetrahydrofolate cyclohydrolase  43.77 
 
 		 285 aa  245  4.9999999999999997e-64  Clostridium thermocellum ATCC 27405  Bacteria  hitchhiker  0.000000512009  n/a   
 
 
-
 
NC_007973  Rmet_1192  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  49.29 
 
 		 285 aa  245  4.9999999999999997e-64  Cupriavidus metallidurans CH34  Bacteria  decreased coverage  0.000194196  normal  1 
 
 
-
 
NC_008463  PA14_41350  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  48.41 
 
 		 284 aa  245  6e-64  Pseudomonas aeruginosa UCBPP-PA14  Bacteria  normal  1  normal  0.471362 
 
 
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