More than 300 homologs were found in PanDaTox collection
for query gene Hore_06480 on replicon NC_011899
Organism: Halothermothrix orenii H 168



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Replicon accession
Locus tag
Product
% identity
Alignment on query gene
Alignment on homolog gene
Length
Bit score

E-value
Organism name
Kingdom
Plasmid clonability
Plasmid unclonability p-value
Fosmid clonability
Fosmid unclonability p-value
Coverage Plot
PanDaTox homologs
Experimental validation
NC_011899  Hore_06480  tetrahydrofolate dehydrogenase/cyclohydrolase  100 
 
 		 283 aa  568  1e-161  Halothermothrix orenii H 168  Bacteria  hitchhiker  0.000000303472  n/a   
 
 
-
 
NC_007644  Moth_1516  methenyltetrahydrofolate cyclohydrolase  63.8 
 
 		 280 aa  349  2e-95  Moorella thermoacetica ATCC 39073  Bacteria  normal  1  normal  1 
 
 
-
 
NC_012034  Athe_0982  Methenyltetrahydrofolate cyclohydrolase  62.5 
 
 		 289 aa  337  9.999999999999999e-92  Anaerocellum thermophilum DSM 6725  Bacteria  hitchhiker  0.000669614  n/a   
 
 
-
 
NC_010424  Daud_0103  methenyltetrahydrofolate cyclohydrolase  59.06 
 
 		 294 aa  327  2.0000000000000001e-88  Candidatus Desulforudis audaxviator MP104C  Bacteria  normal  1  n/a   
 
 
-
 
NC_013501  Rmar_0952  Methenyltetrahydrofolate cyclohydrolase  57.88 
 
 		 293 aa  318  5e-86  Rhodothermus marinus DSM 4252  Bacteria  normal  1  n/a   
 
 
-
 
NC_010718  Nther_1700  5,10-methylenetetrahydrofolate dehydrogenase (NADP+), Methenyltetrahydrofolate cyclohydrolase  55.4 
 
 		 284 aa  318  7e-86  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  1  normal  0.335496 
 
 
-
 
NC_012918  GM21_2719  Methylenetetrahydrofolate dehydrogenase (NADP(+))  56.79 
 
 		 281 aa  317  1e-85  Geobacter sp. M21  Bacteria  n/a    normal  1 
 
 
-
 
NC_011146  Gbem_1497  tetrahydrofolate dehydrogenase/cyclohydrolase  56.07 
 
 		 281 aa  315  4e-85  Geobacter bemidjiensis Bem  Bacteria  hitchhiker  0.0000244416  n/a   
 
 
-
 
NC_009483  Gura_1169  methylenetetrahydrofolate dehydrogenase (NADP(+))  56.43 
 
 		 280 aa  315  7e-85  Geobacter uraniireducens Rf4  Bacteria  hitchhiker  0.00000103166  n/a   
 
 
-
 
NC_009012  Cthe_1093  methenyltetrahydrofolate cyclohydrolase  56.38 
 
 		 285 aa  313  9.999999999999999e-85  Clostridium thermocellum ATCC 27405  Bacteria  hitchhiker  0.000000512009  n/a   
 
 
-
 
NC_007517  Gmet_1162  methenyltetrahydrofolate cyclohydrolase  55.83 
 
 		 285 aa  314  9.999999999999999e-85  Geobacter metallireducens GS-15  Bacteria  hitchhiker  0.00000000377219  hitchhiker  0.00798692 
 
 
-
 
NC_006274  BCZK3934  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  57.09 
 
 		 286 aa  311  6.999999999999999e-84  Bacillus cereus E33L  Bacteria  normal  0.0428362  n/a   
 
 
-
 
NC_005957  BT9727_3923  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  57.09 
 
 		 286 aa  311  7.999999999999999e-84  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  1  n/a   
 
 
-
 
NC_011773  BCAH820_4201  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  57.09 
 
 		 286 aa  311  7.999999999999999e-84  Bacillus cereus AH820  Bacteria  n/a    hitchhiker  3.73931e-16 
 
 
-
 
NC_011772  BCG9842_B0943  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  56.38 
 
 		 286 aa  310  2e-83  Bacillus cereus G9842  Bacteria  normal  1  hitchhiker  0.00348961 
 
 
-
 
NC_009674  Bcer98_2874  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  57.3 
 
 		 286 aa  310  2e-83  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  0.126852  n/a   
 
 
-
 
NC_005945  BAS4085  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  56.74 
 
 		 286 aa  309  2.9999999999999997e-83  Bacillus anthracis str. Sterne  Bacteria  hitchhiker  0.00334729  n/a   
 
 
-
 
NC_011725  BCB4264_A4291  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  56.38 
 
 		 286 aa  309  2.9999999999999997e-83  Bacillus cereus B4264  Bacteria  normal  1  n/a   
 
 
-
 
NC_007530  GBAA_4405  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  56.74 
 
 		 286 aa  309  2.9999999999999997e-83  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  1  n/a   
 
 
-
 
NC_012039  Cla_0581  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  54.35 
 
 		 298 aa  309  2.9999999999999997e-83  Campylobacter lari RM2100  Bacteria  normal  0.388564  n/a   
 
 
-
 
NC_011658  BCAH187_A4311  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  56.74 
 
 		 286 aa  309  2.9999999999999997e-83  Bacillus cereus AH187  Bacteria  normal  0.0277859  n/a   
 
 
-
 
NC_003909  BCE_4254  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  56.74 
 
 		 286 aa  309  4e-83  Bacillus cereus ATCC 10987  Bacteria  normal  0.246013  n/a   
 
 
-
 
NC_009714  CHAB381_1036  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  55.4 
 
 		 284 aa  309  4e-83  Campylobacter hominis ATCC BAA-381  Bacteria  normal  1  n/a   
 
 
-
 
NC_010184  BcerKBAB4_4033  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  56.74 
 
 		 286 aa  308  6.999999999999999e-83  Bacillus weihenstephanensis KBAB4  Bacteria  normal  0.781388  n/a   
 
 
-
 
NC_008340  Mlg_0591  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  55.6 
 
 		 286 aa  305  6e-82  Alkalilimnicola ehrlichii MLHE-1  Bacteria  hitchhiker  0.0000074286  unclonable  2.0108800000000004e-18 
 
 
-
 
NC_008609  Ppro_0480  methenyltetrahydrofolate cyclohydrolase  57.86 
 
 		 283 aa  305  7e-82  Pelobacter propionicus DSM 2379  Bacteria  hitchhiker  0.00000146162  n/a   
 
 
-
 
NC_008576  Mmc1_3712  methenyltetrahydrofolate cyclohydrolase  54.55 
 
 		 285 aa  305  7e-82  Magnetococcus sp. MC-1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_011883  Ddes_2215  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  56.74 
 
 		 285 aa  303  3.0000000000000004e-81  Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774  Bacteria  normal  1  n/a   
 
 
-
 
NC_003912  CJE0942  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  54.15 
 
 		 282 aa  302  4.0000000000000003e-81  Campylobacter jejuni RM1221  Bacteria  normal  1  n/a   
 
 
-
 
NC_010730  SYO3AOP1_1067  Methenyltetrahydrofolate cyclohydrolase  55.76 
 
 		 285 aa  302  4.0000000000000003e-81  Sulfurihydrogenibium sp. YO3AOP1  Bacteria  normal  1  n/a   
 
 
-
 
NC_013202  Hmuk_2214  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  53.4 
 
 		 297 aa  301  8.000000000000001e-81  Halomicrobium mukohataei DSM 12286  Archaea  normal  0.621742  normal  0.605059 
 
 
-
 
NC_013173  Dbac_3223  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  55.56 
 
 		 281 aa  300  2e-80  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  1  n/a   
 
 
-
 
NC_008787  CJJ81176_0871  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  53.43 
 
 		 282 aa  300  2e-80  Campylobacter jejuni subsp. jejuni 81-176  Bacteria  normal  0.0134315  n/a   
 
 
-
 
NC_009802  CCC13826_0832  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  56.23 
 
 		 283 aa  299  4e-80  Campylobacter concisus 13826  Bacteria  normal  0.048214  n/a   
 
 
-
 
NC_010524  Lcho_1643  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  55.64 
 
 		 287 aa  298  8e-80  Leptothrix cholodnii SP-6  Bacteria  n/a    normal  0.0588013 
 
 
-
 
NC_011145  AnaeK_2618  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  57.55 
 
 		 282 aa  297  1e-79  Anaeromyxobacter sp. K  Bacteria  normal  0.442042  n/a   
 
 
-
 
NC_010814  Glov_0508  Methenyltetrahydrofolate cyclohydrolase  55.2 
 
 		 284 aa  298  1e-79  Geobacter lovleyi SZ  Bacteria  decreased coverage  0.0000347177  n/a   
 
 
-
 
NC_012793  GWCH70_2324  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  55 
 
 		 290 aa  297  1e-79  Geobacillus sp. WCH70  Bacteria  hitchhiker  0.0000000808824  n/a   
 
 
-
 
NC_008782  Ajs_2128  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  54.68 
 
 		 282 aa  297  1e-79  Acidovorax sp. JS42  Bacteria  normal  1  normal  0.616371 
 
 
-
 
NC_009715  CCV52592_0799  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  54.32 
 
 		 288 aa  296  2e-79  Campylobacter curvus 525.92  Bacteria  normal  1  n/a   
 
 
-
 
NC_011891  A2cp1_2712  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  57.91 
 
 		 282 aa  296  2e-79  Anaeromyxobacter dehalogenans 2CP-1  Bacteria  normal  1  n/a   
 
 
-
 
NC_007512  Plut_0927  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  53.85 
 
 		 307 aa  297  2e-79  Chlorobium luteolum DSM 273  Bacteria  normal  1  normal  1 
 
 
-
 
NC_008752  Aave_2459  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  54.87 
 
 		 283 aa  296  2e-79  Acidovorax citrulli AAC00-1  Bacteria  normal  0.0798593  normal  1 
 
 
-
 
NC_008309  HS_1221  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  53.38 
 
 		 282 aa  296  2e-79  Haemophilus somnus 129PT  Bacteria  decreased coverage  0.00020406  n/a   
 
 
-
 
NC_007760  Adeh_1247  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  57.91 
 
 		 282 aa  296  3e-79  Anaeromyxobacter dehalogenans 2CP-C  Bacteria  normal  1  n/a   
 
 
-
 
NC_011992  Dtpsy_1654  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  54.32 
 
 		 282 aa  296  3e-79  Acidovorax ebreus TPSY  Bacteria  normal  1  n/a   
 
 
-
 
NC_002939  GSU0862  folD bifunctional protein  54.77 
 
 		 285 aa  296  4e-79  Geobacter sulfurreducens PCA  Bacteria  normal  1  n/a   
 
 
-
 
NC_009707  JJD26997_1004  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  52.71 
 
 		 282 aa  295  4e-79  Campylobacter jejuni subsp. doylei 269.97  Bacteria  normal  0.226194  n/a   
 
 
-
 
NC_002967  TDE0013  methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase  53.08 
 
 		 293 aa  295  8e-79  Treponema denticola ATCC 35405  Bacteria  normal  1  n/a   
 
 
-
 
NC_007514  Cag_0779  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  53.85 
 
 		 295 aa  295  8e-79  Chlorobium chlorochromatii CaD3  Bacteria  normal  1  n/a   
 
 
-
 
NC_011884  Cyan7425_0973  Methylenetetrahydrofolate dehydrogenase (NADP(+))  53.05 
 
 		 293 aa  294  1e-78  Cyanothece sp. PCC 7425  Bacteria  normal  0.150063  normal  0.215441 
 
 
-
 
NC_014148  Plim_3436  Methylenetetrahydrofolate dehydrogenase (NADP(+))  54.39 
 
 		 291 aa  293  2e-78  Planctomyces limnophilus DSM 3776  Bacteria  normal  1  n/a   
 
 
-
 
NC_011060  Ppha_1205  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  53.85 
 
 		 295 aa  293  2e-78  Pelodictyon phaeoclathratiforme BU-1  Bacteria  normal  1  n/a   
 
 
-
 
NC_013158  Huta_2943  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  52.38 
 
 		 297 aa  293  2e-78  Halorhabdus utahensis DSM 12940  Archaea  normal  0.420051  n/a   
 
 
-
 
NC_008639  Cpha266_0997  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  52.92 
 
 		 308 aa  292  3e-78  Chlorobium phaeobacteroides DSM 266  Bacteria  normal  1  n/a   
 
 
-
 
NC_013411  GYMC61_0247  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  55.36 
 
 		 284 aa  292  4e-78  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_008312  Tery_4172  methenyltetrahydrofolate cyclohydrolase  51.42 
 
 		 287 aa  292  4e-78  Trichodesmium erythraeum IMS101  Bacteria  normal  1  normal  0.280923 
 
 
-
 
NC_011059  Paes_1178  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  53.85 
 
 		 295 aa  291  6e-78  Prosthecochloris aestuarii DSM 271  Bacteria  normal  1  normal  0.545639 
 
 
-
 
NC_008789  Hhal_0610  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  54.12 
 
 		 290 aa  291  9e-78  Halorhodospira halophila SL1  Bacteria  normal  0.565768  n/a   
 
 
-
 
NC_010831  Cphamn1_1442  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  53.15 
 
 		 298 aa  291  9e-78  Chlorobium phaeobacteroides BS1  Bacteria  normal  0.56836  normal  1 
 
 
-
 
NC_007347  Reut_A1299  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  54.15 
 
 		 283 aa  290  1e-77  Ralstonia eutropha JMP134  Bacteria  normal  0.293991  n/a   
 
 
-
 
NC_009675  Anae109_2520  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  56.57 
 
 		 281 aa  290  2e-77  Anaeromyxobacter sp. Fw109-5  Bacteria  normal  0.412381  normal  0.0135619 
 
 
-
 
NC_013889  TK90_0603  Methylenetetrahydrofolate dehydrogenase (NADP(+))  53.02 
 
 		 287 aa  290  2e-77  Thioalkalivibrio sp. K90mix  Bacteria  normal  0.399589  normal  0.311345 
 
 
-
 
NC_008599  CFF8240_1174  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  53.6 
 
 		 283 aa  290  2e-77  Campylobacter fetus subsp. fetus 82-40  Bacteria  normal  0.840508  n/a   
 
 
-
 
NC_011898  Ccel_0604  tetrahydrofolate dehydrogenase/cyclohydrolase  54.51 
 
 		 284 aa  290  3e-77  Clostridium cellulolyticum H10  Bacteria  normal  1  n/a   
 
 
-
 
NC_013512  Sdel_0845  Methylenetetrahydrofolate dehydrogenase (NADP(+))  51.81 
 
 		 281 aa  289  4e-77  Sulfurospirillum deleyianum DSM 6946  Bacteria  normal  1  n/a   
 
 
-
 
NC_007614  Nmul_A0357  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  54.71 
 
 		 288 aa  289  4e-77  Nitrosospira multiformis ATCC 25196  Bacteria  normal  0.991729  n/a   
 
 
-
 
NC_010002  Daci_3983  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  53.43 
 
 		 284 aa  288  5.0000000000000004e-77  Delftia acidovorans SPH-1  Bacteria  normal  0.763661  normal  0.0287042 
 
 
-
 
NC_011729  PCC7424_0607  Methenyltetrahydrofolate cyclohydrolase  51.59 
 
 		 301 aa  288  5.0000000000000004e-77  Cyanothece sp. PCC 7424  Bacteria  n/a    normal  1 
 
 
-
 
NC_009487  SaurJH9_1123  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  50.36 
 
 		 286 aa  288  7e-77  Staphylococcus aureus subsp. aureus JH9  Bacteria  hitchhiker  0.000919852  n/a   
 
 
-
 
NC_009632  SaurJH1_1145  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  50.36 
 
 		 286 aa  288  7e-77  Staphylococcus aureus subsp. aureus JH1  Bacteria  hitchhiker  0.00105319  n/a   
 
 
-
 
NC_013517  Sterm_1178  Methylenetetrahydrofolate dehydrogenase (NADP(+))  52.35 
 
 		 285 aa  288  8e-77  Sebaldella termitidis ATCC 33386  Bacteria  hitchhiker  0.0000000836934  n/a   
 
 
-
 
NC_013440  Hoch_3221  Methylenetetrahydrofolate dehydrogenase (NADP(+))  55.71 
 
 		 287 aa  288  9e-77  Haliangium ochraceum DSM 14365  Bacteria  normal  0.690635  normal  0.130494 
 
 
-
 
NC_007963  Csal_2048  methenyltetrahydrofolate cyclohydrolase  54.26 
 
 		 287 aa  286  2e-76  Chromohalobacter salexigens DSM 3043  Bacteria  decreased coverage  0.0000169412  n/a   
 
 
-
 
NC_009668  Oant_3959  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  54.7 
 
 		 299 aa  286  2.9999999999999996e-76  Ochrobactrum anthropi ATCC 49188  Bacteria  normal  0.791035  n/a   
 
 
-
 
NC_011726  PCC8801_1592  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  51.05 
 
 		 292 aa  286  2.9999999999999996e-76  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_011126  HY04AAS1_0893  Methenyltetrahydrofolate cyclohydrolase  52.9 
 
 		 278 aa  285  4e-76  Hydrogenobaculum sp. Y04AAS1  Bacteria  normal  1  n/a   
 
 
-
 
NC_009438  Sputcn32_1488  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  53.85 
 
 		 284 aa  285  4e-76  Shewanella putrefaciens CN-32  Bacteria  hitchhiker  0.000000791428  n/a   
 
 
-
 
NC_008781  Pnap_1778  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  52.54 
 
 		 281 aa  285  5e-76  Polaromonas naphthalenivorans CJ2  Bacteria  normal  1  normal  0.0122285 
 
 
-
 
NC_007519  Dde_0296  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  53.38 
 
 		 286 aa  285  5e-76  Desulfovibrio desulfuricans subsp. desulfuricans str. G20  Bacteria  normal  1  n/a   
 
 
-
 
NC_008751  Dvul_2658  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  52.84 
 
 		 286 aa  285  5.999999999999999e-76  Desulfovibrio vulgaris DP4  Bacteria  normal  0.51858  normal  1 
 
 
-
 
NC_013456  VEA_004081  methylenetetrahydrofolate dehydrogenase (NADP+)/methenyltetrahydrofolate cyclohydrolase  53.57 
 
 		 286 aa  284  1.0000000000000001e-75  Vibrio sp. Ex25  Bacteria  normal  0.897306  n/a   
 
 
-
 
NC_007604  Synpcc7942_0777  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  52.19 
 
 		 289 aa  284  1.0000000000000001e-75  Synechococcus elongatus PCC 7942  Bacteria  normal  0.71594  normal  0.0994354 
 
 
-
 
NC_011901  Tgr7_0937  Methylenetetrahydrofolate dehydrogenase (NADP(+))  54.32 
 
 		 285 aa  284  1.0000000000000001e-75  Thioalkalivibrio sp. HL-EbGR7  Bacteria  normal  0.693292  n/a   
 
 
-
 
NC_008527  LACR_0921  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  53.45 
 
 		 295 aa  284  1.0000000000000001e-75  Lactococcus lactis subsp. cremoris SK11  Bacteria  unclonable  0.0000659615  n/a   
 
 
-
 
NC_014248  Aazo_1506  methenyltetrahydrofolate cyclohydrolase  50.71 
 
 		 294 aa  283  2.0000000000000002e-75  'Nostoc azollae' 0708  Bacteria  normal  1  n/a   
 
 
-
 
NC_007298  Daro_0448  methenyltetrahydrofolate cyclohydrolase  54.35 
 
 		 284 aa  283  2.0000000000000002e-75  Dechloromonas aromatica RCB  Bacteria  normal  0.326868  normal  0.769812 
 
 
-
 
NC_013161  Cyan8802_1617  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  50.7 
 
 		 292 aa  283  3.0000000000000004e-75  Cyanothece sp. PCC 8802  Bacteria  normal  1  normal  1 
 
 
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NC_004116  SAG0494  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  52.69 
 
 		 284 aa  283  3.0000000000000004e-75  Streptococcus agalactiae 2603V/R  Bacteria  normal  1  n/a   
 
 
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NC_004311  BRA0781  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  53.66 
 
 		 299 aa  283  3.0000000000000004e-75  Brucella suis 1330  Bacteria  normal  1  n/a   
 
 
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NC_008825  Mpe_A2131  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  52.35 
 
 		 283 aa  283  3.0000000000000004e-75  Methylibium petroleiphilum PM1  Bacteria  normal  0.386646  normal  1 
 
 
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NC_009504  BOV_A0731  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  53.66 
 
 		 299 aa  283  3.0000000000000004e-75  Brucella ovis ATCC 25840  Bacteria  normal  1  n/a   
 
 
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NC_008463  PA14_41350  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  53.74 
 
 		 284 aa  282  4.0000000000000003e-75  Pseudomonas aeruginosa UCBPP-PA14  Bacteria  normal  1  normal  0.471362 
 
 
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NC_008554  Sfum_2686  methylenetetrahydrofolate dehydrogenase (NADP(+))  51.89 
 
 		 295 aa  282  5.000000000000001e-75  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  0.204372  normal  0.0139654 
 
 
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NC_010803  Clim_1112  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  52.1 
 
 		 296 aa  282  6.000000000000001e-75  Chlorobium limicola DSM 245  Bacteria  normal  1  n/a   
 
 
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NC_010506  Swoo_3115  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  52.1 
 
 		 286 aa  281  6.000000000000001e-75  Shewanella woodyi ATCC 51908  Bacteria  hitchhiker  0.00000143268  decreased coverage  0.000000300932 
 
 
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NC_009783  VIBHAR_01391  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  53.21 
 
 		 286 aa  281  7.000000000000001e-75  Vibrio harveyi ATCC BAA-1116  Bacteria  n/a    n/a   
 
 
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NC_010322  PputGB1_2105  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  54.84 
 
 		 303 aa  281  7.000000000000001e-75  Pseudomonas putida GB-1  Bacteria  normal  0.538628  normal  0.603824 
 
 
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NC_013743  Htur_1699  Methenyltetrahydrofolate cyclohydrolase  50.52 
 
 		 297 aa  281  7.000000000000001e-75  Haloterrigena turkmenica DSM 5511  Archaea  n/a    n/a   
 
 
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NC_009831  Ssed_1539  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  53.36 
 
 		 284 aa  281  1e-74  Shewanella sediminis HAW-EB3  Bacteria  hitchhiker  0.00454653  hitchhiker  0.000334608 
 
 
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