More than 300 homologs were found in PanDaTox collection
for query gene Hlac_1624 on replicon NC_012029
Organism: Halorubrum lacusprofundi ATCC 49239



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Replicon accession
Locus tag
Product
% identity
Alignment on query gene
Alignment on homolog gene
Length
Bit score

E-value
Organism name
Kingdom
Plasmid clonability
Plasmid unclonability p-value
Fosmid clonability
Fosmid unclonability p-value
Coverage Plot
PanDaTox homologs
Experimental validation
NC_012029  Hlac_1624  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  100 
 
 		 307 aa  608  1e-173  Halorubrum lacusprofundi ATCC 49239  Archaea  normal  1  normal  1 
 
 
-
 
NC_013743  Htur_1699  Methenyltetrahydrofolate cyclohydrolase  72.88 
 
 		 297 aa  437  1e-121  Haloterrigena turkmenica DSM 5511  Archaea  n/a    n/a   
 
 
-
 
NC_013922  Nmag_2300  Methenyltetrahydrofolate cyclohydrolase  72.2 
 
 		 297 aa  429  1e-119  Natrialba magadii ATCC 43099  Archaea  normal  1  n/a   
 
 
-
 
NC_013158  Huta_2943  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  74.4 
 
 		 297 aa  429  1e-119  Halorhabdus utahensis DSM 12940  Archaea  normal  0.420051  n/a   
 
 
-
 
NC_013202  Hmuk_2214  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  72.88 
 
 		 297 aa  424  1e-117  Halomicrobium mukohataei DSM 12286  Archaea  normal  0.621742  normal  0.605059 
 
 
-
 
NC_013745  Htur_4705  Methenyltetrahydrofolate cyclohydrolase  70.51 
 
 		 297 aa  396  1e-109  Haloterrigena turkmenica DSM 5511  Archaea  normal  0.0492192  n/a   
 
 
-
 
NC_012918  GM21_2719  Methylenetetrahydrofolate dehydrogenase (NADP(+))  56.69 
 
 		 281 aa  314  9.999999999999999e-85  Geobacter sp. M21  Bacteria  n/a    normal  1 
 
 
-
 
NC_011146  Gbem_1497  tetrahydrofolate dehydrogenase/cyclohydrolase  55.99 
 
 		 281 aa  313  2.9999999999999996e-84  Geobacter bemidjiensis Bem  Bacteria  hitchhiker  0.0000244416  n/a   
 
 
-
 
NC_009483  Gura_1169  methylenetetrahydrofolate dehydrogenase (NADP(+))  55.63 
 
 		 280 aa  309  4e-83  Geobacter uraniireducens Rf4  Bacteria  hitchhiker  0.00000103166  n/a   
 
 
-
 
NC_007517  Gmet_1162  methenyltetrahydrofolate cyclohydrolase  54.74 
 
 		 285 aa  306  3e-82  Geobacter metallireducens GS-15  Bacteria  hitchhiker  0.00000000377219  hitchhiker  0.00798692 
 
 
-
 
NC_002939  GSU0862  folD bifunctional protein  56.49 
 
 		 285 aa  305  6e-82  Geobacter sulfurreducens PCA  Bacteria  normal  1  n/a   
 
 
-
 
NC_007644  Moth_1516  methenyltetrahydrofolate cyclohydrolase  56.69 
 
 		 280 aa  304  1.0000000000000001e-81  Moorella thermoacetica ATCC 39073  Bacteria  normal  1  normal  1 
 
 
-
 
NC_014148  Plim_3436  Methylenetetrahydrofolate dehydrogenase (NADP(+))  55.02 
 
 		 291 aa  302  5.000000000000001e-81  Planctomyces limnophilus DSM 3776  Bacteria  normal  1  n/a   
 
 
-
 
NC_009012  Cthe_1093  methenyltetrahydrofolate cyclohydrolase  50 
 
 		 285 aa  295  8e-79  Clostridium thermocellum ATCC 27405  Bacteria  hitchhiker  0.000000512009  n/a   
 
 
-
 
NC_010718  Nther_1700  5,10-methylenetetrahydrofolate dehydrogenase (NADP+), Methenyltetrahydrofolate cyclohydrolase  52.65 
 
 		 284 aa  294  2e-78  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  1  normal  0.335496 
 
 
-
 
NC_007514  Cag_0779  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  51.75 
 
 		 295 aa  293  4e-78  Chlorobium chlorochromatii CaD3  Bacteria  normal  1  n/a   
 
 
-
 
NC_010655  Amuc_1641  Methenyltetrahydrofolate cyclohydrolase  52.76 
 
 		 291 aa  291  7e-78  Akkermansia muciniphila ATCC BAA-835  Bacteria  normal  1  normal  0.794405 
 
 
-
 
NC_010831  Cphamn1_1442  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  50.7 
 
 		 298 aa  290  3e-77  Chlorobium phaeobacteroides BS1  Bacteria  normal  0.56836  normal  1 
 
 
-
 
NC_012034  Athe_0982  Methenyltetrahydrofolate cyclohydrolase  50.17 
 
 		 289 aa  289  4e-77  Anaerocellum thermophilum DSM 6725  Bacteria  hitchhiker  0.000669614  n/a   
 
 
-
 
NC_007512  Plut_0927  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  51.75 
 
 		 307 aa  288  6e-77  Chlorobium luteolum DSM 273  Bacteria  normal  1  normal  1 
 
 
-
 
NC_010424  Daud_0103  methenyltetrahydrofolate cyclohydrolase  54.39 
 
 		 294 aa  288  7e-77  Candidatus Desulforudis audaxviator MP104C  Bacteria  normal  1  n/a   
 
 
-
 
NC_009714  CHAB381_1036  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  49.3 
 
 		 284 aa  287  1e-76  Campylobacter hominis ATCC BAA-381  Bacteria  normal  1  n/a   
 
 
-
 
NC_008639  Cpha266_0997  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  51.22 
 
 		 308 aa  287  2e-76  Chlorobium phaeobacteroides DSM 266  Bacteria  normal  1  n/a   
 
 
-
 
NC_011059  Paes_1178  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  50.7 
 
 		 295 aa  285  5e-76  Prosthecochloris aestuarii DSM 271  Bacteria  normal  1  normal  0.545639 
 
 
-
 
NC_008044  TM1040_2356  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  56.45 
 
 		 300 aa  285  5e-76  Ruegeria sp. TM1040  Bacteria  normal  1  normal  0.531119 
 
 
-
 
NC_008609  Ppro_0480  methenyltetrahydrofolate cyclohydrolase  54.77 
 
 		 283 aa  285  1.0000000000000001e-75  Pelobacter propionicus DSM 2379  Bacteria  hitchhiker  0.00000146162  n/a   
 
 
-
 
NC_010814  Glov_0508  Methenyltetrahydrofolate cyclohydrolase  54.58 
 
 		 284 aa  284  1.0000000000000001e-75  Geobacter lovleyi SZ  Bacteria  decreased coverage  0.0000347177  n/a   
 
 
-
 
NC_011060  Ppha_1205  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  50.7 
 
 		 295 aa  284  1.0000000000000001e-75  Pelodictyon phaeoclathratiforme BU-1  Bacteria  normal  1  n/a   
 
 
-
 
NC_008576  Mmc1_3712  methenyltetrahydrofolate cyclohydrolase  52.74 
 
 		 285 aa  285  1.0000000000000001e-75  Magnetococcus sp. MC-1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_011662  Tmz1t_3190  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  53.87 
 
 		 295 aa  281  7.000000000000001e-75  Thauera sp. MZ1T  Bacteria  normal  0.905813  n/a   
 
 
-
 
NC_010803  Clim_1112  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  51.05 
 
 		 296 aa  281  9e-75  Chlorobium limicola DSM 245  Bacteria  normal  1  n/a   
 
 
-
 
NC_013739  Cwoe_3588  Methylenetetrahydrofolate dehydrogenase (NADP(+))  53.66 
 
 		 283 aa  281  9e-75  Conexibacter woesei DSM 14684  Bacteria  normal  0.24704  normal  0.653023 
 
 
-
 
NC_011899  Hore_06480  tetrahydrofolate dehydrogenase/cyclohydrolase  51.23 
 
 		 283 aa  281  1e-74  Halothermothrix orenii H 168  Bacteria  hitchhiker  0.000000303472  n/a   
 
 
-
 
NC_013501  Rmar_0952  Methenyltetrahydrofolate cyclohydrolase  53.85 
 
 		 293 aa  281  1e-74  Rhodothermus marinus DSM 4252  Bacteria  normal  1  n/a   
 
 
-
 
NC_002967  TDE0013  methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase  51.21 
 
 		 293 aa  280  3e-74  Treponema denticola ATCC 35405  Bacteria  normal  1  n/a   
 
 
-
 
NC_011883  Ddes_2215  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  52.65 
 
 		 285 aa  278  8e-74  Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774  Bacteria  normal  1  n/a   
 
 
-
 
NC_008554  Sfum_2686  methylenetetrahydrofolate dehydrogenase (NADP(+))  46.92 
 
 		 295 aa  278  1e-73  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  0.204372  normal  0.0139654 
 
 
-
 
NC_009455  DehaBAV1_0637  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  49.47 
 
 		 296 aa  276  3e-73  Dehalococcoides sp. BAV1  Bacteria  normal  1  n/a   
 
 
-
 
NC_002936  DET0668  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  48.77 
 
 		 296 aa  276  4e-73  Dehalococcoides ethenogenes 195  Bacteria  normal  1  n/a   
 
 
-
 
NC_002936  DET0702  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  48.77 
 
 		 296 aa  276  4e-73  Dehalococcoides ethenogenes 195  Bacteria  normal  1  n/a   
 
 
-
 
NC_013552  DhcVS_606  methylenetetrahydrofolate dehydrogenase (NADP+)/methenyltetrahydrofolate cyclohydrolase  48.77 
 
 		 296 aa  275  5e-73  Dehalococcoides sp. VS  Bacteria  normal  1  n/a   
 
 
-
 
NC_007520  Tcr_0723  methylenetetrahydrofolate dehydrogenase (NADP+)  50.88 
 
 		 309 aa  275  5e-73  Thiomicrospira crunogena XCL-2  Bacteria  hitchhiker  0.00000000206547  n/a   
 
 
-
 
NC_008340  Mlg_0591  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  50.18 
 
 		 286 aa  275  5e-73  Alkalilimnicola ehrlichii MLHE-1  Bacteria  hitchhiker  0.0000074286  unclonable  2.0108800000000004e-18 
 
 
-
 
NC_009715  CCV52592_0799  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  48.59 
 
 		 288 aa  275  7e-73  Campylobacter curvus 525.92  Bacteria  normal  1  n/a   
 
 
-
 
NC_007298  Daro_0448  methenyltetrahydrofolate cyclohydrolase  51.41 
 
 		 284 aa  274  1.0000000000000001e-72  Dechloromonas aromatica RCB  Bacteria  normal  0.326868  normal  0.769812 
 
 
-
 
NC_009712  Mboo_2188  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  50.7 
 
 		 278 aa  274  1.0000000000000001e-72  Candidatus Methanoregula boonei 6A8  Archaea  normal  0.590033  normal  1 
 
 
-
 
NC_013162  Coch_1786  Methenyltetrahydrofolate cyclohydrolase  50.35 
 
 		 291 aa  274  2.0000000000000002e-72  Capnocytophaga ochracea DSM 7271  Bacteria  normal  0.431166  n/a   
 
 
-
 
NC_009441  Fjoh_0243  methenyltetrahydrofolate cyclohydrolase  47.59 
 
 		 295 aa  273  2.0000000000000002e-72  Flavobacterium johnsoniae UW101  Bacteria  normal  0.424565  n/a   
 
 
-
 
NC_007519  Dde_0296  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  50.89 
 
 		 286 aa  272  5.000000000000001e-72  Desulfovibrio desulfuricans subsp. desulfuricans str. G20  Bacteria  normal  1  n/a   
 
 
-
 
NC_007802  Jann_0983  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  51.34 
 
 		 308 aa  271  8.000000000000001e-72  Jannaschia sp. CCS1  Bacteria  normal  0.170937  normal  1 
 
 
-
 
NC_012793  GWCH70_2324  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  49.65 
 
 		 290 aa  271  1e-71  Geobacillus sp. WCH70  Bacteria  hitchhiker  0.0000000808824  n/a   
 
 
-
 
NC_010622  Bphy_1475  methenyltetrahydrofolate cyclohydrolase  50.7 
 
 		 285 aa  271  1e-71  Burkholderia phymatum STM815  Bacteria  normal  0.996402  normal  1 
 
 
-
 
NC_009943  Dole_2033  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  46.62 
 
 		 303 aa  270  2e-71  Desulfococcus oleovorans Hxd3  Bacteria  hitchhiker  0.00000535348  n/a   
 
 
-
 
NC_003912  CJE0942  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  47.54 
 
 		 282 aa  270  2.9999999999999997e-71  Campylobacter jejuni RM1221  Bacteria  normal  1  n/a   
 
 
-
 
NC_009675  Anae109_2520  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  53.87 
 
 		 281 aa  270  2.9999999999999997e-71  Anaeromyxobacter sp. Fw109-5  Bacteria  normal  0.412381  normal  0.0135619 
 
 
-
 
NC_007614  Nmul_A0357  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  53.17 
 
 		 288 aa  270  2.9999999999999997e-71  Nitrosospira multiformis ATCC 25196  Bacteria  normal  0.991729  n/a   
 
 
-
 
NC_009802  CCC13826_0832  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  48.8 
 
 		 283 aa  270  2.9999999999999997e-71  Campylobacter concisus 13826  Bacteria  normal  0.048214  n/a   
 
 
-
 
NC_010681  Bphyt_2595  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  52.31 
 
 		 286 aa  270  2.9999999999999997e-71  Burkholderia phytofirmans PsJN  Bacteria  normal  0.439263  hitchhiker  0.00799235 
 
 
-
 
NC_011145  AnaeK_2618  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  53.87 
 
 		 282 aa  269  4e-71  Anaeromyxobacter sp. K  Bacteria  normal  0.442042  n/a   
 
 
-
 
NC_010531  Pnec_0703  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  49.3 
 
 		 284 aa  269  4e-71  Polynucleobacter necessarius subsp. necessarius STIR1  Bacteria  normal  0.32895  normal  0.316701 
 
 
-
 
NC_008752  Aave_2459  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  49.65 
 
 		 283 aa  269  5e-71  Acidovorax citrulli AAC00-1  Bacteria  normal  0.0798593  normal  1 
 
 
-
 
NC_011891  A2cp1_2712  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  53.87 
 
 		 282 aa  269  5e-71  Anaeromyxobacter dehalogenans 2CP-1  Bacteria  normal  1  n/a   
 
 
-
 
NC_008751  Dvul_2658  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  50 
 
 		 286 aa  269  5e-71  Desulfovibrio vulgaris DP4  Bacteria  normal  0.51858  normal  1 
 
 
-
 
NC_007951  Bxe_A1536  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  51.96 
 
 		 286 aa  268  5.9999999999999995e-71  Burkholderia xenovorans LB400  Bacteria  normal  1  normal  0.341066 
 
 
-
 
NC_010524  Lcho_0175  methenyltetrahydrofolate cyclohydrolase  50.35 
 
 		 301 aa  268  8e-71  Leptothrix cholodnii SP-6  Bacteria  n/a    normal  1 
 
 
-
 
NC_008787  CJJ81176_0871  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  46.83 
 
 		 282 aa  268  8.999999999999999e-71  Campylobacter jejuni subsp. jejuni 81-176  Bacteria  normal  0.0134315  n/a   
 
 
-
 
NC_013456  VEA_004081  methylenetetrahydrofolate dehydrogenase (NADP+)/methenyltetrahydrofolate cyclohydrolase  51.24 
 
 		 286 aa  268  1e-70  Vibrio sp. Ex25  Bacteria  normal  0.897306  n/a   
 
 
-
 
NC_007760  Adeh_1247  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  53.52 
 
 		 282 aa  267  1e-70  Anaeromyxobacter dehalogenans 2CP-C  Bacteria  normal  1  n/a   
 
 
-
 
NC_008782  Ajs_2128  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  49.12 
 
 		 282 aa  267  2e-70  Acidovorax sp. JS42  Bacteria  normal  1  normal  0.616371 
 
 
-
 
NC_013173  Dbac_3223  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  49.82 
 
 		 281 aa  267  2e-70  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  1  n/a   
 
 
-
 
NC_011992  Dtpsy_1654  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  49.12 
 
 		 282 aa  267  2e-70  Acidovorax ebreus TPSY  Bacteria  normal  1  n/a   
 
 
-
 
NC_008553  Mthe_1242  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  48.41 
 
 		 280 aa  266  2.9999999999999995e-70  Methanosaeta thermophila PT  Archaea  normal  0.92121  n/a   
 
 
-
 
NC_011898  Ccel_0604  tetrahydrofolate dehydrogenase/cyclohydrolase  47.22 
 
 		 284 aa  266  4e-70  Clostridium cellulolyticum H10  Bacteria  normal  1  n/a   
 
 
-
 
NC_013512  Sdel_0845  Methylenetetrahydrofolate dehydrogenase (NADP(+))  47.89 
 
 		 281 aa  266  5e-70  Sulfurospirillum deleyianum DSM 6946  Bacteria  normal  1  n/a   
 
 
-
 
NC_009674  Bcer98_2874  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  45.94 
 
 		 286 aa  266  5e-70  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  0.126852  n/a   
 
 
-
 
NC_013517  Sterm_1178  Methylenetetrahydrofolate dehydrogenase (NADP(+))  47.54 
 
 		 285 aa  265  7e-70  Sebaldella termitidis ATCC 33386  Bacteria  hitchhiker  0.0000000836934  n/a   
 
 
-
 
NC_009783  VIBHAR_01391  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  50.88 
 
 		 286 aa  265  8e-70  Vibrio harveyi ATCC BAA-1116  Bacteria  n/a    n/a   
 
 
-
 
NC_009428  Rsph17025_0571  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  52.3 
 
 		 296 aa  265  1e-69  Rhodobacter sphaeroides ATCC 17025  Bacteria  normal  1  normal  1 
 
 
-
 
NC_011832  Mpal_0744  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  49.83 
 
 		 280 aa  264  1e-69  Methanosphaerula palustris E1-9c  Archaea  normal  1  normal  1 
 
 
-
 
NC_010501  PputW619_1739  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  50.7 
 
 		 284 aa  264  1e-69  Pseudomonas putida W619  Bacteria  normal  1  normal  0.168227 
 
 
-
 
NC_008599  CFF8240_1174  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  48.24 
 
 		 283 aa  264  1e-69  Campylobacter fetus subsp. fetus 82-40  Bacteria  normal  0.840508  n/a   
 
 
-
 
NC_009051  Memar_1834  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  50.17 
 
 		 283 aa  263  2e-69  Methanoculleus marisnigri JR1  Archaea  normal  1  n/a   
 
 
-
 
NC_007347  Reut_A1299  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  50 
 
 		 283 aa  263  2e-69  Ralstonia eutropha JMP134  Bacteria  normal  0.293991  n/a   
 
 
-
 
NC_009049  Rsph17029_2314  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  53 
 
 		 296 aa  263  2e-69  Rhodobacter sphaeroides ATCC 17029  Bacteria  normal  1  normal  0.206347 
 
 
-
 
NC_010084  Bmul_1130  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  50.18 
 
 		 285 aa  263  2e-69  Burkholderia multivorans ATCC 17616  Bacteria  normal  1  normal  0.675331 
 
 
-
 
NC_007963  Csal_2048  methenyltetrahydrofolate cyclohydrolase  50.35 
 
 		 287 aa  264  2e-69  Chromohalobacter salexigens DSM 3043  Bacteria  decreased coverage  0.0000169412  n/a   
 
 
-
 
NC_008789  Hhal_0610  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  50.88 
 
 		 290 aa  264  2e-69  Halorhodospira halophila SL1  Bacteria  normal  0.565768  n/a   
 
 
-
 
NC_007005  Psyr_1743  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  51.58 
 
 		 284 aa  263  3e-69  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  0.83996  normal  1 
 
 
-
 
NC_007493  RSP_0661  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  53 
 
 		 296 aa  263  3e-69  Rhodobacter sphaeroides 2.4.1  Bacteria  normal  1  n/a   
 
 
-
 
NC_008781  Pnap_1778  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  48.24 
 
 		 281 aa  263  3e-69  Polaromonas naphthalenivorans CJ2  Bacteria  normal  1  normal  0.0122285 
 
 
-
 
NC_009439  Pmen_3471  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  49.83 
 
 		 307 aa  263  3e-69  Pseudomonas mendocina ymp  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009656  PSPA7_3507  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  50.53 
 
 		 284 aa  263  3e-69  Pseudomonas aeruginosa PA7  Bacteria  normal  1  n/a   
 
 
-
 
NC_007354  Ecaj_0680  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  48.46 
 
 		 300 aa  263  4e-69  Ehrlichia canis str. Jake  Bacteria  normal  1  n/a   
 
 
-
 
NC_009707  JJD26997_1004  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  45.77 
 
 		 282 aa  263  4e-69  Campylobacter jejuni subsp. doylei 269.97  Bacteria  normal  0.226194  n/a   
 
 
-
 
NC_008825  Mpe_A2131  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  49.65 
 
 		 283 aa  262  4.999999999999999e-69  Methylibium petroleiphilum PM1  Bacteria  normal  0.386646  normal  1 
 
 
-
 
NC_008254  Meso_0152  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  50.34 
 
 		 298 aa  262  4.999999999999999e-69  Chelativorans sp. BNC1  Bacteria  normal  0.386  n/a   
 
 
-
 
NC_011004  Rpal_0417  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  50.53 
 
 		 295 aa  261  8e-69  Rhodopseudomonas palustris TIE-1  Bacteria  normal  0.940252  n/a   
 
 
-
 
NC_007492  Pfl01_3699  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  49.82 
 
 		 284 aa  261  8e-69  Pseudomonas fluorescens Pf0-1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_008463  PA14_41350  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  50.18 
 
 		 284 aa  261  8e-69  Pseudomonas aeruginosa UCBPP-PA14  Bacteria  normal  1  normal  0.471362 
 
 
-
 
NC_002947  PP_2265  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  50.35 
 
 		 284 aa  261  8.999999999999999e-69  Pseudomonas putida KT2440  Bacteria  normal  0.382632  decreased coverage  0.000766726 
 
 
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