252 decreased-coverage genes were found for selected organism/s



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Locus tag
Gene type
Replicon accession
From
To
Strand
Gene Length
Product
Protein accession
Plasmid clonability
Plasmid unclonability p-value
Fosmid clonability
Fosmid unclonability p-value
Organism name
Kingdom
Coverage Plot
PanDaTox homologs
Experimental validation
M446_0036  CDS  NC_010511  37700  39727  -  2028  methylmalonyl-CoA mutase, large subunit  YP_001767058  normal  0.0637775  decreased coverage  0.00272797  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_0037  CDS  NC_010511  40013  41308  +  1296  crotonyl-CoA reductase  YP_001767059  normal  1  decreased coverage  0.00205217  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_0106  CDS  NC_010511  124073  126649  -  2577  hypothetical protein  YP_001767125  decreased coverage  0.00890818  normal  0.867993  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_0234  CDS  NC_010511  284088  286163  -  2076  3-hydroxyacyl-CoA dehydrogenase NAD-binding  YP_001767240  normal  1  decreased coverage  0.00586824  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_0235  CDS  NC_010511  286262  287464  -  1203  acetyl-CoA acetyltransferase  YP_001767241  normal  1  decreased coverage  0.00445966  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_0240  CDS  NC_010511  293180  293671  +  492  CheW protein  YP_001767246  normal  1  decreased coverage  0.00382894  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_0294  CDS  NC_010511  359361  361580  +  2220  aldehyde oxidase and xanthine dehydrogenase molybdopterin binding  YP_001767299  normal  1  decreased coverage  0.00152892  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_0295  CDS  NC_010511  362109  365852  -  3744  ribonucleotide-diphosphate reductase subunit alpha  YP_001767300  normal  1  decreased coverage  0.00235826  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_0296  CDS  NC_010511  366469  366885  +  417  NADH:ubiquinone oxidoreductase subunit  YP_001767301  normal  0.511676  decreased coverage  0.000705293  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_0297  CDS  NC_010511  366947  367579  +  633  hypothetical protein  YP_001767302  normal  0.445535  decreased coverage  0.00079076  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_0405  CDS  NC_010511  489836  491935  +  2100  penicillin-binding protein 1C  YP_001767408  decreased coverage  0.00905597  normal  0.606283  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_0420    NC_010511  504469  504759  +  291      decreased coverage  0.00669044  normal  0.0142176  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_0434  CDS  NC_010511  517852  518505  +  654  ABC transporter related  YP_001767435  normal  0.554012  decreased coverage  0.00307291  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_0435  CDS  NC_010511  518745  519986  +  1242  capsule polysaccharide export protein-like protein  YP_001767436  normal  1  decreased coverage  0.00121431  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_0436  CDS  NC_010511  519999  520772  +  774  hypothetical protein  YP_001767437  normal  1  decreased coverage  0.00271012  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_0437    NC_010511  520912  521952  +  1041      normal  1  decreased coverage  0.00280053  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_0494  CDS  NC_010511  583263  584426  -  1164  N-acetylglucosamine-6-phosphate deacetylase  YP_001767491  normal  1  decreased coverage  0.000235914  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_0495  CDS  NC_010511  584423  585442  -  1020  glutamine--fructose-6-phosphate transaminase (isomerizing)  YP_001767492  normal  1  decreased coverage  0.000215608  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_0496  CDS  NC_010511  585439  586338  -  900  N-acetylmuramic acid-6-phosphate etherase  YP_001767493  normal  1  decreased coverage  0.000201517  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_0497  CDS  NC_010511  586456  588075  -  1620  extracellular solute-binding protein  YP_001767494  normal  1  decreased coverage  0.00026016  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_0515  CDS  NC_010511  613309  614469  -  1161  DHH superfamily phosphohydrolase  YP_001767512  decreased coverage  0.00174696  hitchhiker  0.000956825  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_0583    NC_010511  686572  689052  +  2481      normal  1  decreased coverage  0.00150779  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_0584  CDS  NC_010511  689196  689447  +  252  hypothetical protein  YP_001767579  normal  0.18507  decreased coverage  0.00189585  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_0585  CDS  NC_010511  689457  689729  -  273  hypothetical protein  YP_001767580  normal  0.293332  decreased coverage  0.00178671  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_0586  CDS  NC_010511  689848  690240  +  393  hypothetical protein  YP_001767581  normal  0.211329  decreased coverage  0.00177483  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_0626  CDS  NC_010511  728134  728781  -  648  SNARE associated Golgi protein  YP_001767621  normal  0.228359  decreased coverage  0.00442875  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_0627  CDS  NC_010511  728843  729343  -  501  hypothetical protein  YP_001767622  normal  0.299074  decreased coverage  0.00428994  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_0628  CDS  NC_010511  729340  731046  -  1707  ATP dependent DNA ligase  YP_001767623  normal  0.639244  decreased coverage  0.00714589  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_0629  CDS  NC_010511  731043  732140  -  1098  putative mRNA 3-end processing factor  YP_001767624  normal  0.88354  decreased coverage  0.00579405  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_0950  CDS  NC_010511  1076397  1077404  +  1008  extensin family protein  YP_001767933  decreased coverage  0.00924534  normal  1  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_0951  CDS  NC_010511  1077367  1077825  -  459  hypothetical protein  YP_001767934  decreased coverage  0.00820335  normal  1  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_1094  CDS  NC_010511  1218655  1220049  -  1395  cytochrome P450  YP_001768056  normal  1  decreased coverage  0.00217839  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_1360  CDS  NC_010511  1499887  1500060  -  174  hypothetical protein  YP_001768310  decreased coverage  0.00813462  normal  0.0520803  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_1416  CDS  NC_010511  1558001  1558918  +  918  hypothetical protein  YP_001768366  decreased coverage  0.0078754  normal  0.193293  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_1585  CDS  NC_010511  1770277  1773120  +  2844  arginine decarboxylase  YP_001768520  normal  1  decreased coverage  0.00962069  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_1630    NC_010511  1824559  1824756  +  198      normal  0.219549  decreased coverage  0.00961071  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_1634  CDS  NC_010511  1826843  1828225  -  1383  phospho-2-dehydro-3-deoxyheptonate aldolase  YP_001768562  normal  1  decreased coverage  0.00700823  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_1656  CDS  NC_010511  1852493  1853200  +  708  histidine utilization repressor  YP_001768583  decreased coverage  0.00445076  normal  0.818618  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_1767  CDS  NC_010511  1981208  1982092  +  885  hypothetical protein  YP_001768691  decreased coverage  0.000998556  normal  0.212334  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_1776    NC_010511  1991609  1991989  -  381      normal  0.030503  decreased coverage  0.00442875  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_1777    NC_010511  1992080  1992241  +  162      normal  0.132474  decreased coverage  0.00428994  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_1778  CDS  NC_010511  1992409  1994229  -  1821  multi-sensor signal transduction histidine kinase  YP_001768700  normal  0.415214  decreased coverage  0.0072817  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_1779  CDS  NC_010511  1994342  1994587  -  246  heavy metal transport/detoxification protein  YP_001768701  normal  0.616941  decreased coverage  0.00478886  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_1780  CDS  NC_010511  1994890  1996374  +  1485  diguanylate phosphodiesterase  YP_001768702  normal  0.459436  decreased coverage  0.0080021  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_1781  CDS  NC_010511  1996382  1997341  -  960  hypothetical protein  YP_001768703  normal  0.8404  decreased coverage  0.00637263  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_2030  CDS  NC_010511  2265825  2266565  -  741  hypothetical protein  YP_001768928  decreased coverage  0.00948439  normal  0.0263672  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_2031  CDS  NC_010511  2266555  2267031  -  477  putative general secretion pathway protein H precursor  YP_001768929  decreased coverage  0.00566537  normal  0.0245477  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_2032  CDS  NC_010511  2267326  2268093  -  768  hypothetical protein  YP_001768930  decreased coverage  0.00792656  normal  0.0108899  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_2045  CDS  NC_010511  2279800  2282238  -  2439  PAS/PAC sensor hybrid histidine kinase  YP_001768942  normal  1  decreased coverage  0.000148537  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_2100  CDS  NC_010511  2351997  2352629  -  633  pyridoxamine 5'-phosphate oxidase  YP_001768996  normal  1  decreased coverage  0.00869837  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_2101  CDS  NC_010511  2352717  2353205  +  489  hypothetical protein  YP_001768997  normal  1  decreased coverage  0.00853617  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_2104  CDS  NC_010511  2356023  2356601  +  579  hypothetical protein  YP_001769000  normal  0.707478  decreased coverage  0.00974706  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_2105  CDS  NC_010511  2356606  2357340  -  735  pseudouridine synthase  YP_001769001  normal  1  decreased coverage  0.00908459  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_2112  CDS  NC_010511  2363503  2363973  +  471  hypothetical protein  YP_001769008  normal  1  decreased coverage  0.00624927  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_2113  CDS  NC_010511  2363995  2365038  -  1044  protein of unknown function DUF900 hydrolase family protein  YP_001769009  normal  1  decreased coverage  0.00719162  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_2114  CDS  NC_010511  2365251  2366231  +  981  arginine/ornithine transport system ATPase  YP_001769010  normal  1  decreased coverage  0.00605272  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_2123  CDS  NC_010511  2372884  2373333  +  450  AsnC family transcriptional regulator  YP_001769019  normal  0.0513877  decreased coverage  0.00440064  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_2143  CDS  NC_010511  2391064  2392083  +  1020  putative signal peptide  YP_001769039  decreased coverage  0.00697757  normal  0.275291  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_2199  CDS  NC_010511  2445555  2447171  -  1617  AMP-dependent synthetase and ligase  YP_001769094  decreased coverage  0.00574882  normal  0.320928  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_2213  CDS  NC_010511  2467223  2467843  -  621  urease, gamma subunit  YP_001769108  normal  1  decreased coverage  0.0025871  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_2214  CDS  NC_010511  2467920  2468768  -  849  urease accessory protein UreD  YP_001769109  normal  1  decreased coverage  0.00280053  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_2243  CDS  NC_010511  2499735  2500868  -  1134  glutamate--cysteine ligase GCS2  YP_001769138  decreased coverage  0.0053932  normal  0.199506  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_2244  CDS  NC_010511  2500937  2501734  -  798  hypothetical protein  YP_001769139  decreased coverage  0.00252887  normal  0.186395  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_2258  CDS  NC_010511  2515643  2515981  +  339  hypothetical protein  YP_001769152  normal  1  decreased coverage  0.00160562  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_2259  CDS  NC_010511  2516289  2516717  +  429  ATP-dependent Clp protease adaptor protein ClpS  YP_001769153  normal  1  decreased coverage  0.0015949  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_2260  CDS  NC_010511  2516739  2519192  +  2454  ATP-dependent Clp protease, ATP-binding subunit clpA  YP_001769154  normal  1  decreased coverage  0.00108561  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_2265  CDS  NC_010511  2523592  2524920  -  1329  TRAP transporter solute receptor TAXI family protein  YP_001769159  normal  1  decreased coverage  0.00194673  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_2266  CDS  NC_010511  2525171  2525368  -  198  hypothetical protein  YP_001769160  normal  1  decreased coverage  0.00138576  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_2267  CDS  NC_010511  2525647  2526363  -  717  ABC transporter related  YP_001769161  normal  1  decreased coverage  0.00164993  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_2268  CDS  NC_010511  2526360  2527148  -  789  ABC transporter related  YP_001769162  normal  0.434627  decreased coverage  0.00162775  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_2289  CDS  NC_010511  2546970  2548142  -  1173  methyltransferase type 11  YP_001769183  decreased coverage  0.00766724  normal  0.036458  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_2307  CDS  NC_010511  2567413  2568306  -  894  inner-membrane translocator  YP_001769201  normal  1  decreased coverage  0.00760667  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_2309  CDS  NC_010511  2570285  2571094  -  810  ABC transporter related  YP_001769203  normal  1  decreased coverage  0.0078002  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_2310  CDS  NC_010511  2571329  2571991  +  663  TetR family transcriptional regulator  YP_001769204  normal  0.987325  decreased coverage  0.00710043  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_2311  CDS  NC_010511  2571963  2573195  -  1233  putative phenylacetate-CoA ligase  YP_001769205  normal  1  decreased coverage  0.00962069  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_2312  CDS  NC_010511  2573262  2573759  -  498  hypothetical protein  YP_001769206  normal  0.571534  decreased coverage  0.00751047  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_2329  CDS  NC_010511  2593606  2594241  -  636  glutathione S-transferase domain-containing protein  YP_001769222  decreased coverage  0.00249355  normal  0.144066  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_2339  CDS  NC_010511  2603577  2606456  -  2880  diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)  YP_001769232  decreased coverage  0.00277698  normal  0.215878  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_2389  CDS  NC_010511  2657315  2657890  +  576  TadE family protein  YP_001769281  decreased coverage  0.007335  hitchhiker  0.00469436  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_2394  CDS  NC_010511  2661056  2662153  +  1098  GTP-dependent nucleic acid-binding protein EngD  YP_001769286  normal  0.207486  decreased coverage  0.00637263  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_2443  CDS  NC_010511  2705937  2706698  -  762  precorrin-6x reductase  YP_001769332  decreased coverage  0.00747936  normal  0.0784333  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_2444  CDS  NC_010511  2706697  2707941  +  1245  precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit  YP_001769333  decreased coverage  0.000686479  normal  0.0788368  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_2664  CDS  NC_010511  2955157  2955693  +  537  inorganic pyrophosphatase  YP_001769537  decreased coverage  0.00365311  normal  0.143617  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_2739    NC_010511  3044022  3044447  -  426      normal  0.972827  decreased coverage  0.00696256  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_2940  CDS  NC_010511  3255358  3256566  -  1209  hypothetical protein  YP_001769786  normal  1  decreased coverage  0.00513133  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_2966  CDS  NC_010511  3290208  3291368  -  1161  diguanylate cyclase  YP_001769812  normal  0.0175816  decreased coverage  0.00586824  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_2967  CDS  NC_010511  3291669  3292952  +  1284  uncharacterized membrane-anchored protein  YP_001769813  normal  0.104827  decreased coverage  0.00682829  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_2980  CDS  NC_010511  3303748  3303969  +  222  cold-shock DNA-binding domain-containing protein  YP_001769826  decreased coverage  0.0073832  normal  0.0936276  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_3054  CDS  NC_010511  3379659  3379919  -  261  hypothetical protein  YP_001769899  decreased coverage  0.00949087  normal  0.0156802  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_3055  CDS  NC_010511  3380320  3382107  -  1788  cyclic beta-1,2-glucan ABC transporter  YP_001769900  normal  0.0704257  decreased coverage  0.00962069  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_3099  CDS  NC_010511  3430028  3430459  +  432  MerR family transcriptional regulator  YP_001769943  hitchhiker  0.00609185  decreased coverage  0.00847969  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_3101  CDS  NC_010511  3432201  3432836  -  636  riboflavin synthase, alpha subunit  YP_001769945  decreased coverage  0.00905036  decreased coverage  0.00949736  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_3104  CDS  NC_010511  3434661  3435962  -  1302  serine hydroxymethyltransferase  YP_001769948  normal  0.425727  decreased coverage  0.00549191  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_3131  CDS  NC_010511  3465664  3466110  +  447  ribose-5-phosphate isomerase B  YP_001769974  normal  1  decreased coverage  0.00448812  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_3132  CDS  NC_010511  3466131  3467057  +  927  ribokinase-like domain-containing protein  YP_001769975  normal  1  decreased coverage  0.00509823  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_3133    NC_010511  3467201  3467368  -  168      normal  1  decreased coverage  0.004318  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_3184  CDS  NC_010511  3523001  3523900  -  900  hypothetical protein  YP_001770024  normal  1  decreased coverage  0.00255327  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_3187  CDS  NC_010511  3527242  3528408  -  1167  amidohydrolase  YP_001770027  normal  1  decreased coverage  0.0033512  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_3188  CDS  NC_010511  3528615  3529493  +  879  aldose 1-epimerase  YP_001770028  normal  1  decreased coverage  0.00301236  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
M446_3189  CDS  NC_010511  3529607  3530569  +  963  integrase family protein  YP_001770029  normal  1  decreased coverage  0.00303256  Methylobacterium sp. 4-46  Bacteria 
 
 
-
 
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