More than 300 homologs were found in PanDaTox collection
for query gene Francci3_1492 on replicon NC_007777
Organism: Frankia sp. CcI3



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_007777  Francci3_1492  methenyltetrahydrofolate cyclohydrolase  100 
 
 
276 aa  532  1e-150  Frankia sp. CcI3  Bacteria  normal  0.310861  normal 
 
 
-
 
NC_009921  Franean1_4183  methylenetetrahydrofolate dehydrogenase (NADP(+))  72.89 
 
 
275 aa  355  3.9999999999999996e-97  Frankia sp. EAN1pec  Bacteria  normal  0.0949993  normal  0.629252 
 
 
-
 
NC_013947  Snas_5040  Methylenetetrahydrofolate dehydrogenase (NADP(+))  59.57 
 
 
276 aa  267  1e-70  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  0.462607  normal  0.33784 
 
 
-
 
NC_011886  Achl_3465  Methylenetetrahydrofolate dehydrogenase (NADP(+))  47.48 
 
 
291 aa  224  2e-57  Arthrobacter chlorophenolicus A6  Bacteria  n/a    normal 
 
 
-
 
NC_010718  Nther_1700  5,10-methylenetetrahydrofolate dehydrogenase (NADP+), Methenyltetrahydrofolate cyclohydrolase  42.34 
 
 
284 aa  221  9e-57  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  normal  0.335496 
 
 
-
 
NC_007644  Moth_1516  methenyltetrahydrofolate cyclohydrolase  43.12 
 
 
280 aa  221  9.999999999999999e-57  Moorella thermoacetica ATCC 39073  Bacteria  normal  normal 
 
 
-
 
NC_011146  Gbem_1497  tetrahydrofolate dehydrogenase/cyclohydrolase  42.24 
 
 
281 aa  218  7e-56  Geobacter bemidjiensis Bem  Bacteria  hitchhiker  0.0000244416  n/a   
 
 
-
 
NC_009767  Rcas_0735  methenyltetrahydrofolate cyclohydrolase  46.38 
 
 
288 aa  218  1e-55  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.768044  normal 
 
 
-
 
NC_012034  Athe_0982  Methenyltetrahydrofolate cyclohydrolase  43.31 
 
 
289 aa  217  2e-55  Anaerocellum thermophilum DSM 6725  Bacteria  hitchhiker  0.000669614  n/a   
 
 
-
 
NC_012918  GM21_2719  Methylenetetrahydrofolate dehydrogenase (NADP(+))  41.3 
 
 
281 aa  216  2.9999999999999998e-55  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_013757  Gobs_2877  Methylenetetrahydrofolate dehydrogenase (NADP(+))  50.55 
 
 
279 aa  214  9.999999999999999e-55  Geodermatophilus obscurus DSM 43160  Bacteria  normal  0.0989232  n/a   
 
 
-
 
NC_009487  SaurJH9_1123  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  40.94 
 
 
286 aa  214  1.9999999999999998e-54  Staphylococcus aureus subsp. aureus JH9  Bacteria  hitchhiker  0.000919852  n/a   
 
 
-
 
NC_009632  SaurJH1_1145  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  40.94 
 
 
286 aa  214  1.9999999999999998e-54  Staphylococcus aureus subsp. aureus JH1  Bacteria  hitchhiker  0.00105319  n/a   
 
 
-
 
NC_007517  Gmet_1162  methenyltetrahydrofolate cyclohydrolase  42.18 
 
 
285 aa  212  5.999999999999999e-54  Geobacter metallireducens GS-15  Bacteria  hitchhiker  0.00000000377219  hitchhiker  0.00798692 
 
 
-
 
NC_009483  Gura_1169  methylenetetrahydrofolate dehydrogenase (NADP(+))  40.58 
 
 
280 aa  211  1e-53  Geobacter uraniireducens Rf4  Bacteria  hitchhiker  0.00000103166  n/a   
 
 
-
 
NC_013173  Dbac_3223  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  44 
 
 
281 aa  211  1e-53  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  n/a   
 
 
-
 
NC_009714  CHAB381_1036  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  39.35 
 
 
284 aa  209  4e-53  Campylobacter hominis ATCC BAA-381  Bacteria  normal  n/a   
 
 
-
 
NC_008148  Rxyl_0827  methenyltetrahydrofolate cyclohydrolase  44.09 
 
 
284 aa  209  4e-53  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  0.997708  n/a   
 
 
-
 
NC_008609  Ppro_0480  methenyltetrahydrofolate cyclohydrolase  41.09 
 
 
283 aa  208  6e-53  Pelobacter propionicus DSM 2379  Bacteria  hitchhiker  0.00000146162  n/a   
 
 
-
 
NC_013595  Sros_0348  Methylenetetrahydrofolate dehydrogenase (NADP(+))  51.09 
 
 
279 aa  207  1e-52  Streptosporangium roseum DSM 43021  Bacteria  normal  normal 
 
 
-
 
NC_011772  BCG9842_B0943  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  40.43 
 
 
286 aa  207  1e-52  Bacillus cereus G9842  Bacteria  normal  hitchhiker  0.00348961 
 
 
-
 
NC_012793  GWCH70_2324  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  41.94 
 
 
290 aa  207  1e-52  Geobacillus sp. WCH70  Bacteria  hitchhiker  0.0000000808824  n/a   
 
 
-
 
NC_013411  GYMC61_0247  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  44.44 
 
 
284 aa  208  1e-52  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_006274  BCZK3934  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  40.79 
 
 
286 aa  206  3e-52  Bacillus cereus E33L  Bacteria  normal  0.0428362  n/a   
 
 
-
 
NC_011658  BCAH187_A4311  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  40.79 
 
 
286 aa  206  3e-52  Bacillus cereus AH187  Bacteria  normal  0.0277859  n/a   
 
 
-
 
NC_003909  BCE_4254  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  40.79 
 
 
286 aa  206  4e-52  Bacillus cereus ATCC 10987  Bacteria  normal  0.246013  n/a   
 
 
-
 
NC_005957  BT9727_3923  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  40.79 
 
 
286 aa  206  4e-52  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  n/a   
 
 
-
 
NC_011725  BCB4264_A4291  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  40.43 
 
 
286 aa  206  4e-52  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_011773  BCAH820_4201  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  40.79 
 
 
286 aa  206  4e-52  Bacillus cereus AH820  Bacteria  n/a    hitchhiker  3.73931e-16 
 
 
-
 
NC_009674  Bcer98_2874  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  40.07 
 
 
286 aa  206  4e-52  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  0.126852  n/a   
 
 
-
 
NC_009012  Cthe_1093  methenyltetrahydrofolate cyclohydrolase  37.32 
 
 
285 aa  206  5e-52  Clostridium thermocellum ATCC 27405  Bacteria  hitchhiker  0.000000512009  n/a   
 
 
-
 
NC_010814  Glov_0508  Methenyltetrahydrofolate cyclohydrolase  42.09 
 
 
284 aa  206  5e-52  Geobacter lovleyi SZ  Bacteria  decreased coverage  0.0000347177  n/a   
 
 
-
 
NC_013739  Cwoe_3588  Methylenetetrahydrofolate dehydrogenase (NADP(+))  45.85 
 
 
283 aa  206  5e-52  Conexibacter woesei DSM 14684  Bacteria  normal  0.24704  normal  0.653023 
 
 
-
 
NC_002976  SERP0648  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  40.22 
 
 
286 aa  205  8e-52  Staphylococcus epidermidis RP62A  Bacteria  normal  n/a   
 
 
-
 
NC_008527  LACR_0921  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  41.67 
 
 
295 aa  204  9e-52  Lactococcus lactis subsp. cremoris SK11  Bacteria  unclonable  0.0000659615  n/a   
 
 
-
 
NC_011831  Cagg_0060  Methenyltetrahydrofolate cyclohydrolase  43.77 
 
 
285 aa  204  1e-51  Chloroflexus aggregans DSM 9485  Bacteria  normal  normal  0.296483 
 
 
-
 
NC_005945  BAS4085  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  40.43 
 
 
286 aa  204  2e-51  Bacillus anthracis str. Sterne  Bacteria  hitchhiker  0.00334729  n/a   
 
 
-
 
NC_007530  GBAA_4405  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  40.43 
 
 
286 aa  204  2e-51  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  n/a   
 
 
-
 
NC_009253  Dred_1073  methylenetetrahydrofolate dehydrogenase (NADP(+))  40.22 
 
 
284 aa  202  3e-51  Desulfotomaculum reducens MI-1  Bacteria  normal  0.174822  n/a   
 
 
-
 
NC_010184  BcerKBAB4_4033  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  40.07 
 
 
286 aa  203  3e-51  Bacillus weihenstephanensis KBAB4  Bacteria  normal  0.781388  n/a   
 
 
-
 
NC_009051  Memar_1834  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  45.42 
 
 
283 aa  203  3e-51  Methanoculleus marisnigri JR1  Archaea  normal  n/a   
 
 
-
 
NC_009523  RoseRS_4392  methylenetetrahydrofolate dehydrogenase (NADP(+))  45.29 
 
 
288 aa  202  3e-51  Roseiflexus sp. RS-1  Bacteria  normal  0.553346  normal 
 
 
-
 
NC_008752  Aave_2459  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  42.09 
 
 
283 aa  203  3e-51  Acidovorax citrulli AAC00-1  Bacteria  normal  0.0798593  normal 
 
 
-
 
NC_012791  Vapar_2159  Methylenetetrahydrofolate dehydrogenase (NADP(+))  42.81 
 
 
283 aa  203  3e-51  Variovorax paradoxus S110  Bacteria  normal  0.639508  n/a   
 
 
-
 
NC_007298  Daro_0448  methenyltetrahydrofolate cyclohydrolase  41.67 
 
 
284 aa  202  5e-51  Dechloromonas aromatica RCB  Bacteria  normal  0.326868  normal  0.769812 
 
 
-
 
NC_011883  Ddes_2215  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  42.7 
 
 
285 aa  201  9.999999999999999e-51  Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774  Bacteria  normal  n/a   
 
 
-
 
NC_009972  Haur_4471  methenyltetrahydrofolate cyclohydrolase  42.24 
 
 
286 aa  201  9.999999999999999e-51  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  n/a   
 
 
-
 
NC_008576  Mmc1_3712  methenyltetrahydrofolate cyclohydrolase  42.65 
 
 
285 aa  201  9.999999999999999e-51  Magnetococcus sp. MC-1  Bacteria  normal  normal 
 
 
-
 
NC_011899  Hore_06480  tetrahydrofolate dehydrogenase/cyclohydrolase  39.71 
 
 
283 aa  200  1.9999999999999998e-50  Halothermothrix orenii H 168  Bacteria  hitchhiker  0.000000303472  n/a   
 
 
-
 
NC_008781  Pnap_1778  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  42.03 
 
 
281 aa  200  3e-50  Polaromonas naphthalenivorans CJ2  Bacteria  normal  normal  0.0122285 
 
 
-
 
NC_002939  GSU0862  folD bifunctional protein  41.52 
 
 
285 aa  199  5e-50  Geobacter sulfurreducens PCA  Bacteria  normal  n/a   
 
 
-
 
NC_008554  Sfum_2686  methylenetetrahydrofolate dehydrogenase (NADP(+))  38.89 
 
 
295 aa  198  7.999999999999999e-50  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  0.204372  normal  0.0139654 
 
 
-
 
NC_009802  CCC13826_0832  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  41.37 
 
 
283 aa  197  1.0000000000000001e-49  Campylobacter concisus 13826  Bacteria  normal  0.048214  n/a   
 
 
-
 
NC_007925  RPC_0059  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  43.46 
 
 
295 aa  197  1.0000000000000001e-49  Rhodopseudomonas palustris BisB18  Bacteria  normal  normal 
 
 
-
 
NC_004311  BRA0781  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  43.36 
 
 
299 aa  197  2.0000000000000003e-49  Brucella suis 1330  Bacteria  normal  n/a   
 
 
-
 
NC_009504  BOV_A0731  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  43.36 
 
 
299 aa  197  2.0000000000000003e-49  Brucella ovis ATCC 25840  Bacteria  normal  n/a   
 
 
-
 
NC_009715  CCV52592_0799  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  40.79 
 
 
288 aa  197  2.0000000000000003e-49  Campylobacter curvus 525.92  Bacteria  normal  n/a   
 
 
-
 
NC_008599  CFF8240_1174  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  39.35 
 
 
283 aa  197  2.0000000000000003e-49  Campylobacter fetus subsp. fetus 82-40  Bacteria  normal  0.840508  n/a   
 
 
-
 
NC_009338  Mflv_4879  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  44.77 
 
 
286 aa  196  3e-49  Mycobacterium gilvum PYR-GCK  Bacteria  normal  normal  0.0903189 
 
 
-
 
NC_007347  Reut_A1299  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  42.09 
 
 
283 aa  196  4.0000000000000005e-49  Ralstonia eutropha JMP134  Bacteria  normal  0.293991  n/a   
 
 
-
 
NC_011884  Cyan7425_0973  Methylenetetrahydrofolate dehydrogenase (NADP(+))  42.6 
 
 
293 aa  195  6e-49  Cyanothece sp. PCC 7425  Bacteria  normal  0.150063  normal  0.215441 
 
 
-
 
NC_011830  Dhaf_3496  Methylenetetrahydrofolate dehydrogenase (NADP(+))  39.19 
 
 
284 aa  195  6e-49  Desulfitobacterium hafniense DCB-2  Bacteria  normal  n/a   
 
 
-
 
NC_007778  RPB_0108  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  43.26 
 
 
295 aa  195  6e-49  Rhodopseudomonas palustris HaA2  Bacteria  normal  0.55778  normal 
 
 
-
 
NC_011662  Tmz1t_3190  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  42.81 
 
 
295 aa  195  8.000000000000001e-49  Thauera sp. MZ1T  Bacteria  normal  0.905813  n/a   
 
 
-
 
NC_002967  TDE0013  methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase  39.44 
 
 
293 aa  193  2e-48  Treponema denticola ATCC 35405  Bacteria  normal  n/a   
 
 
-
 
NC_011004  Rpal_0417  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  43.11 
 
 
295 aa  194  2e-48  Rhodopseudomonas palustris TIE-1  Bacteria  normal  0.940252  n/a   
 
 
-
 
NC_009668  Oant_3959  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  42.31 
 
 
299 aa  193  2e-48  Ochrobactrum anthropi ATCC 49188  Bacteria  normal  0.791035  n/a   
 
 
-
 
NC_009428  Rsph17025_0571  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  44.09 
 
 
296 aa  194  2e-48  Rhodobacter sphaeroides ATCC 17025  Bacteria  normal  normal 
 
 
-
 
NC_007973  Rmet_1192  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  42.03 
 
 
285 aa  193  2e-48  Cupriavidus metallidurans CH34  Bacteria  decreased coverage  0.000194196  normal 
 
 
-
 
NC_008751  Dvul_2658  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  43.11 
 
 
286 aa  194  2e-48  Desulfovibrio vulgaris DP4  Bacteria  normal  0.51858  normal 
 
 
-
 
NC_008340  Mlg_0591  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  41.01 
 
 
286 aa  194  2e-48  Alkalilimnicola ehrlichii MLHE-1  Bacteria  hitchhiker  0.0000074286  unclonable  2.0108800000000004e-18 
 
 
-
 
NC_010424  Daud_1022  methenyltetrahydrofolate cyclohydrolase  40.15 
 
 
287 aa  193  3e-48  Candidatus Desulforudis audaxviator MP104C  Bacteria  normal  0.394203  n/a   
 
 
-
 
NC_007575  Suden_1113  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  37.99 
 
 
285 aa  193  3e-48  Sulfurimonas denitrificans DSM 1251  Bacteria  normal  0.947222  n/a   
 
 
-
 
NC_009379  Pnuc_0731  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  41.01 
 
 
284 aa  193  3e-48  Polynucleobacter necessarius subsp. asymbioticus QLW-P1DMWA-1  Bacteria  normal  0.945506  n/a   
 
 
-
 
NC_013743  Htur_1699  Methenyltetrahydrofolate cyclohydrolase  40.78 
 
 
297 aa  192  4e-48  Haloterrigena turkmenica DSM 5511  Archaea  n/a    n/a   
 
 
-
 
NC_009455  DehaBAV1_0637  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  41.52 
 
 
296 aa  192  5e-48  Dehalococcoides sp. BAV1  Bacteria  normal  n/a   
 
 
-
 
NC_007519  Dde_0296  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  40.93 
 
 
286 aa  192  5e-48  Desulfovibrio desulfuricans subsp. desulfuricans str. G20  Bacteria  normal  n/a   
 
 
-
 
NC_011898  Ccel_0604  tetrahydrofolate dehydrogenase/cyclohydrolase  38.91 
 
 
284 aa  192  5e-48  Clostridium cellulolyticum H10  Bacteria  normal  n/a   
 
 
-
 
NC_007948  Bpro_2675  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  41.3 
 
 
281 aa  192  5e-48  Polaromonas sp. JS666  Bacteria  normal  normal 
 
 
-
 
NC_007614  Nmul_A0357  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  39.93 
 
 
288 aa  192  6e-48  Nitrosospira multiformis ATCC 25196  Bacteria  normal  0.991729  n/a   
 
 
-
 
NC_013202  Hmuk_2214  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  39.58 
 
 
297 aa  191  7e-48  Halomicrobium mukohataei DSM 12286  Archaea  normal  0.621742  normal  0.605059 
 
 
-
 
NC_007796  Mhun_0022  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  41.61 
 
 
279 aa  192  7e-48  Methanospirillum hungatei JF-1  Archaea  normal  normal 
 
 
-
 
NC_009485  BBta_0269  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  43.82 
 
 
294 aa  192  7e-48  Bradyrhizobium sp. BTAi1  Bacteria  normal  normal 
 
 
-
 
NC_007493  RSP_0661  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  43.73 
 
 
296 aa  191  8e-48  Rhodobacter sphaeroides 2.4.1  Bacteria  normal  n/a   
 
 
-
 
NC_009049  Rsph17029_2314  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  43.37 
 
 
296 aa  191  8e-48  Rhodobacter sphaeroides ATCC 17029  Bacteria  normal  normal  0.206347 
 
 
-
 
NC_002936  DET0668  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  41.87 
 
 
296 aa  191  1e-47  Dehalococcoides ethenogenes 195  Bacteria  normal  n/a   
 
 
-
 
NC_002936  DET0702  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  41.87 
 
 
296 aa  191  1e-47  Dehalococcoides ethenogenes 195  Bacteria  normal  n/a   
 
 
-
 
NC_011832  Mpal_0744  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  40.15 
 
 
280 aa  191  1e-47  Methanosphaerula palustris E1-9c  Archaea  normal  normal 
 
 
-
 
NC_013512  Sdel_0845  Methylenetetrahydrofolate dehydrogenase (NADP(+))  37.55 
 
 
281 aa  191  1e-47  Sulfurospirillum deleyianum DSM 6946  Bacteria  normal  n/a   
 
 
-
 
NC_008825  Mpe_A2131  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  41.3 
 
 
283 aa  191  1e-47  Methylibium petroleiphilum PM1  Bacteria  normal  0.386646  normal 
 
 
-
 
NC_013922  Nmag_2300  Methenyltetrahydrofolate cyclohydrolase  40.14 
 
 
297 aa  191  1e-47  Natrialba magadii ATCC 43099  Archaea  normal  n/a   
 
 
-
 
NC_011661  Dtur_1636  Methenyltetrahydrofolate cyclohydrolase  36.96 
 
 
281 aa  191  2e-47  Dictyoglomus turgidum DSM 6724  Bacteria  normal  n/a   
 
 
-
 
NC_013552  DhcVS_606  methylenetetrahydrofolate dehydrogenase (NADP+)/methenyltetrahydrofolate cyclohydrolase  41.87 
 
 
296 aa  190  2e-47  Dehalococcoides sp. VS  Bacteria  normal  n/a   
 
 
-
 
NC_007958  RPD_0694  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  42.05 
 
 
295 aa  190  2e-47  Rhodopseudomonas palustris BisB5  Bacteria  normal  normal 
 
 
-
 
NC_011126  HY04AAS1_0893  Methenyltetrahydrofolate cyclohydrolase  38.71 
 
 
278 aa  191  2e-47  Hydrogenobaculum sp. Y04AAS1  Bacteria  normal  n/a   
 
 
-
 
NC_012029  Hlac_1624  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  40.14 
 
 
307 aa  190  2e-47  Halorubrum lacusprofundi ATCC 49239  Archaea  normal  normal 
 
 
-
 
NC_007204  Psyc_0673  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  37.18 
 
 
295 aa  189  2.9999999999999997e-47  Psychrobacter arcticus 273-4  Bacteria  normal  normal 
 
 
-
 
NC_007908  Rfer_2209  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  41.67 
 
 
287 aa  189  2.9999999999999997e-47  Rhodoferax ferrireducens T118  Bacteria  normal  0.699057  n/a   
 
 
-
 
NC_013501  Rmar_0952  Methenyltetrahydrofolate cyclohydrolase  42.81 
 
 
293 aa  190  2.9999999999999997e-47  Rhodothermus marinus DSM 4252  Bacteria  normal  n/a   
 
 
-
 
NC_010320  Teth514_1535  methenyltetrahydrofolate cyclohydrolase  35.64 
 
 
286 aa  189  4e-47  Thermoanaerobacter sp. X514  Bacteria  normal  0.0500443  n/a   
 
 
-
 
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