More than 300 homologs were found in PanDaTox collection
for query gene M446_0245 on replicon NC_010511
Organism: Methylobacterium sp. 4-46



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_010511  M446_0245  response regulator receiver modulated CheB methylesterase  100 
 
 
355 aa  678    Methylobacterium sp. 4-46  Bacteria  normal  0.134095  normal  0.0445956 
 
 
-
 
NC_011894  Mnod_5454  response regulator receiver modulated CheB methylesterase  89.3 
 
 
355 aa  602  1.0000000000000001e-171  Methylobacterium nodulans ORS 2060  Bacteria  normal  0.114593  n/a   
 
 
-
 
NC_010172  Mext_2840  protein-glutamate methylesterase  70.77 
 
 
361 aa  469  1.0000000000000001e-131  Methylobacterium extorquens PA1  Bacteria  normal  normal 
 
 
-
 
NC_011757  Mchl_3066  response regulator receiver modulated CheB methylesterase  70.77 
 
 
361 aa  469  1.0000000000000001e-131  Methylobacterium chloromethanicum CM4  Bacteria  normal  0.285498  normal  0.979529 
 
 
-
 
NC_010505  Mrad2831_2187  response regulator receiver modulated CheB methylesterase  69.23 
 
 
355 aa  462  1e-129  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  normal 
 
 
-
 
NC_010725  Mpop_2958  response regulator receiver modulated CheB methylesterase  70.66 
 
 
361 aa  448  1e-125  Methylobacterium populi BJ001  Bacteria  normal  normal 
 
 
-
 
NC_011365  Gdia_3079  response regulator receiver modulated CheB methylesterase  58.67 
 
 
362 aa  348  1e-94  Gluconacetobacter diazotrophicus PAl 5  Bacteria  normal  hitchhiker  0.00742041 
 
 
-
 
NC_007614  Nmul_A0334  response regulator receiver (CheY-like) modulated CheB methylesterase  43.6 
 
 
355 aa  268  1e-70  Nitrosospira multiformis ATCC 25196  Bacteria  normal  0.395325  n/a   
 
 
-
 
NC_007948  Bpro_2467  response regulator receiver (CheY-like) modulated CheB methylesterase  39.72 
 
 
369 aa  256  6e-67  Polaromonas sp. JS666  Bacteria  normal  0.272955  normal  0.0644131 
 
 
-
 
NC_013161  Cyan8802_0791  response regulator receiver modulated CheB methylesterase  39.78 
 
 
367 aa  253  3e-66  Cyanothece sp. PCC 8802  Bacteria  normal  normal 
 
 
-
 
NC_011726  PCC8801_0765  response regulator receiver modulated CheB methylesterase  39.78 
 
 
367 aa  253  3e-66  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_008576  Mmc1_1835  response regulator receiver modulated CheB methylesterase  40 
 
 
376 aa  250  3e-65  Magnetococcus sp. MC-1  Bacteria  hitchhiker  0.00461138  normal 
 
 
-
 
NC_012918  GM21_1835  response regulator receiver modulated CheB methylesterase  41.89 
 
 
369 aa  242  7.999999999999999e-63  Geobacter sp. M21  Bacteria  n/a    hitchhiker  0.00395601 
 
 
-
 
NC_011146  Gbem_2383  response regulator receiver modulated CheB methylesterase  41 
 
 
369 aa  241  1e-62  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_009767  Rcas_4208  response regulator receiver modulated CheB methylesterase  39.3 
 
 
377 aa  241  2e-62  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.484579  normal  0.112955 
 
 
-
 
NC_007517  Gmet_2711  response regulator receiver (CheY-like) modulated CheB methylesterase  40.59 
 
 
347 aa  241  2e-62  Geobacter metallireducens GS-15  Bacteria  normal  normal 
 
 
-
 
NC_011146  Gbem_2026  response regulator receiver modulated CheB methylesterase  40.34 
 
 
351 aa  239  4e-62  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_012918  GM21_2193  response regulator receiver modulated CheB methylesterase  41.14 
 
 
351 aa  239  4e-62  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_011832  Mpal_1330  response regulator receiver modulated CheB methylesterase  40.48 
 
 
351 aa  239  6.999999999999999e-62  Methanosphaerula palustris E1-9c  Archaea  normal  normal 
 
 
-
 
NC_009523  RoseRS_0034  response regulator receiver modulated CheB methylesterase  39.1 
 
 
382 aa  234  2.0000000000000002e-60  Roseiflexus sp. RS-1  Bacteria  normal  normal 
 
 
-
 
NC_009767  Rcas_3196  response regulator receiver modulated CheB methylesterase  44.22 
 
 
346 aa  233  5e-60  Roseiflexus castenholzii DSM 13941  Bacteria  normal  normal  0.287158 
 
 
-
 
NC_009483  Gura_4172  response regulator receiver modulated CheB methylesterase  37.91 
 
 
347 aa  229  7e-59  Geobacter uraniireducens Rf4  Bacteria  normal  n/a   
 
 
-
 
NC_009675  Anae109_2298  response regulator receiver modulated CheB methylesterase  40.58 
 
 
338 aa  228  1e-58  Anaeromyxobacter sp. Fw109-5  Bacteria  normal  0.981818  normal 
 
 
-
 
NC_012918  GM21_2358  response regulator receiver modulated CheB methylesterase  39.26 
 
 
342 aa  228  1e-58  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_012918  GM21_3220  chemotaxis-specific methylesterase  40.34 
 
 
363 aa  228  1e-58  Geobacter sp. M21  Bacteria  n/a    normal  0.184496 
 
 
-
 
NC_007643  Rru_A1406  two component CheB methylesterase  38.74 
 
 
363 aa  227  3e-58  Rhodospirillum rubrum ATCC 11170  Bacteria  normal  0.890909  n/a   
 
 
-
 
NC_007796  Mhun_0988  response regulator receiver (CheY-like) modulated CheB methylesterase  38.84 
 
 
350 aa  227  3e-58  Methanospirillum hungatei JF-1  Archaea  hitchhiker  0.00710031  normal  0.382594 
 
 
-
 
NC_009483  Gura_2165  chemotaxis-specific methylesterase  36.63 
 
 
362 aa  227  3e-58  Geobacter uraniireducens Rf4  Bacteria  unclonable  0.00000000178188  n/a   
 
 
-
 
NC_011146  Gbem_1041  chemotaxis-specific methylesterase  38.64 
 
 
363 aa  226  4e-58  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_010465  YPK_1757  chemotaxis-specific methylesterase  38.16 
 
 
349 aa  225  9e-58  Yersinia pseudotuberculosis YPIII  Bacteria  normal  0.982649  n/a   
 
 
-
 
NC_009708  YpsIP31758_1645  chemotaxis-specific methylesterase  38.16 
 
 
349 aa  225  9e-58  Yersinia pseudotuberculosis IP 31758  Bacteria  normal  n/a   
 
 
-
 
NC_010159  YpAngola_A3519  chemotaxis-specific methylesterase  38.16 
 
 
349 aa  225  9e-58  Yersinia pestis Angola  Bacteria  normal  normal  0.480358 
 
 
-
 
NC_007517  Gmet_1075  chemotaxis-specific methylesterase  37.4 
 
 
363 aa  224  1e-57  Geobacter metallireducens GS-15  Bacteria  normal  hitchhiker  0.00340521 
 
 
-
 
NC_009485  BBta_2148  chemotaxis response regulator protein CheB-glutamate methylesterase  39.83 
 
 
352 aa  224  2e-57  Bradyrhizobium sp. BTAi1  Bacteria  normal  normal 
 
 
-
 
NC_011831  Cagg_2403  response regulator receiver modulated CheB methylesterase  39.26 
 
 
361 aa  221  9.999999999999999e-57  Chloroflexus aggregans DSM 9485  Bacteria  normal  normal  0.141209 
 
 
-
 
NC_009436  Ent638_2454  chemotaxis-specific methylesterase  35.83 
 
 
349 aa  221  1.9999999999999999e-56  Enterobacter sp. 638  Bacteria  normal  0.699312  normal 
 
 
-
 
NC_009832  Spro_2980  chemotaxis-specific methylesterase  37.82 
 
 
349 aa  220  3e-56  Serratia proteamaculans 568  Bacteria  normal  normal 
 
 
-
 
NC_007355  Mbar_A0985  chemotaxis protein-glutamate methylesterase  35.93 
 
 
364 aa  219  6e-56  Methanosarcina barkeri str. Fusaro  Archaea  normal  normal 
 
 
-
 
NC_009523  RoseRS_0994  response regulator receiver modulated CheB methylesterase  41.6 
 
 
346 aa  218  2e-55  Roseiflexus sp. RS-1  Bacteria  normal  normal 
 
 
-
 
NC_009485  BBta_7833  response regulator receiver modulated CheB methylesterase  39.33 
 
 
364 aa  218  2e-55  Bradyrhizobium sp. BTAi1  Bacteria  normal  normal 
 
 
-
 
NC_011353  ECH74115_2621  chemotaxis-specific methylesterase  35 
 
 
349 aa  216  2.9999999999999998e-55  Escherichia coli O157:H7 str. EC4115  Bacteria  normal  hitchhiker  0.000000506638 
 
 
-
 
NC_011149  SeAg_B1205  chemotaxis-specific methylesterase  35.28 
 
 
349 aa  216  4e-55  Salmonella enterica subsp. enterica serovar Agona str. SL483  Bacteria  normal  n/a   
 
 
-
 
NC_011205  SeD_A1328  chemotaxis-specific methylesterase  35.28 
 
 
349 aa  216  4e-55  Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853  Bacteria  normal  hitchhiker  0.0000000000107644 
 
 
-
 
NC_010498  EcSMS35_1301  chemotaxis-specific methylesterase  35 
 
 
349 aa  216  5e-55  Escherichia coli SMS-3-5  Bacteria  normal  hitchhiker  0.00345426 
 
 
-
 
NC_011080  SNSL254_A2077  chemotaxis-specific methylesterase  35.57 
 
 
349 aa  216  5e-55  Salmonella enterica subsp. enterica serovar Newport str. SL254  Bacteria  normal  hitchhiker  0.000000000000138075 
 
 
-
 
NC_011083  SeHA_C2132  chemotaxis-specific methylesterase  35.57 
 
 
349 aa  216  5e-55  Salmonella enterica subsp. enterica serovar Heidelberg str. SL476  Bacteria  normal  hitchhiker  0.0000000000000304139 
 
 
-
 
CP001509  ECD_01854  chemotaxis-specific methylesterase  35 
 
 
349 aa  216  5.9999999999999996e-55  Escherichia coli BL21(DE3)  Bacteria  normal  n/a   
 
 
-
 
NC_012880  Dd703_1516  chemotaxis-specific methylesterase  35.77 
 
 
350 aa  216  5.9999999999999996e-55  Dickeya dadantii Ech703  Bacteria  normal  n/a   
 
 
-
 
NC_012892  B21_01843  hypothetical protein  35 
 
 
349 aa  216  5.9999999999999996e-55  Escherichia coli BL21  Bacteria  normal  0.80551  n/a   
 
 
-
 
NC_010468  EcolC_1749  chemotaxis-specific methylesterase  35 
 
 
349 aa  216  5.9999999999999996e-55  Escherichia coli ATCC 8739  Bacteria  normal  normal 
 
 
-
 
NC_009800  EcHS_A1979  chemotaxis-specific methylesterase  35 
 
 
349 aa  216  5.9999999999999996e-55  Escherichia coli HS  Bacteria  normal  n/a   
 
 
-
 
NC_009801  EcE24377A_2116  chemotaxis-specific methylesterase  35 
 
 
349 aa  216  7e-55  Escherichia coli E24377A  Bacteria  normal  0.823717  n/a   
 
 
-
 
NC_013421  Pecwa_1859  chemotaxis-specific methylesterase  35.46 
 
 
350 aa  215  7e-55  Pectobacterium wasabiae WPP163  Bacteria  normal  n/a   
 
 
-
 
NC_011094  SeSA_A2072  chemotaxis-specific methylesterase  35.29 
 
 
349 aa  215  9e-55  Salmonella enterica subsp. enterica serovar Schwarzengrund str. CVM19633  Bacteria  normal  0.959311  hitchhiker  0.000931228 
 
 
-
 
CP001637  EcDH1_1757  response regulator receiver modulated CheB methylesterase  35 
 
 
349 aa  215  9.999999999999999e-55  Escherichia coli DH1  Bacteria  normal  0.416964  n/a   
 
 
-
 
NC_009972  Haur_0727  response regulator receiver modulated CheB methylesterase  37.11 
 
 
360 aa  214  9.999999999999999e-55  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  0.941174  n/a   
 
 
-
 
NC_007651  BTH_I3177  chemotaxis-specific methylesterase  37.6 
 
 
364 aa  215  9.999999999999999e-55  Burkholderia thailandensis E264  Bacteria  normal  n/a   
 
 
-
 
NC_012912  Dd1591_1544  chemotaxis-specific methylesterase  36.34 
 
 
350 aa  214  9.999999999999999e-55  Dickeya zeae Ech1591  Bacteria  normal  0.381226  n/a   
 
 
-
 
NC_010084  Bmul_0170  chemotaxis-specific methylesterase  38.18 
 
 
363 aa  215  9.999999999999999e-55  Burkholderia multivorans ATCC 17616  Bacteria  normal  normal  0.425756 
 
 
-
 
NC_008390  Bamb_0174  chemotaxis-specific methylesterase  37.93 
 
 
360 aa  214  9.999999999999999e-55  Burkholderia ambifaria AMMD  Bacteria  normal  0.51198  n/a   
 
 
-
 
NC_010551  BamMC406_0187  chemotaxis-specific methylesterase  38.14 
 
 
363 aa  215  9.999999999999999e-55  Burkholderia ambifaria MC40-6  Bacteria  normal  normal 
 
 
-
 
NC_007510  Bcep18194_A3363  chemotaxis-specific methylesterase  37.96 
 
 
363 aa  214  1.9999999999999998e-54  Burkholderia sp. 383  Bacteria  normal  0.0170519  normal 
 
 
-
 
NC_007947  Mfla_1930  chemotaxis-specific methylesterase  36.01 
 
 
355 aa  214  1.9999999999999998e-54  Methylobacillus flagellatus KT  Bacteria  normal  normal 
 
 
-
 
NC_012857  Rpic12D_4166  chemotaxis-specific methylesterase  37.33 
 
 
375 aa  214  1.9999999999999998e-54  Ralstonia pickettii 12D  Bacteria  normal  0.904429  normal 
 
 
-
 
NC_010678  Rpic_4054  chemotaxis-specific methylesterase  37.33 
 
 
375 aa  214  1.9999999999999998e-54  Ralstonia pickettii 12J  Bacteria  normal  normal 
 
 
-
 
NC_009943  Dole_0878  response regulator receiver modulated CheB methylesterase  39.23 
 
 
378 aa  213  2.9999999999999995e-54  Desulfococcus oleovorans Hxd3  Bacteria  normal  n/a   
 
 
-
 
NC_012560  Avin_27980  chemotaxis response regulator; CheB  39.2 
 
 
353 aa  214  2.9999999999999995e-54  Azotobacter vinelandii DJ  Bacteria  normal  0.151486  n/a   
 
 
-
 
NC_009675  Anae109_2366  response regulator receiver modulated CheB methylesterase  40.82 
 
 
352 aa  213  3.9999999999999995e-54  Anaeromyxobacter sp. Fw109-5  Bacteria  normal  0.73319  hitchhiker  0.0000774303 
 
 
-
 
NC_008060  Bcen_2846  chemotaxis-specific methylesterase  38.15 
 
 
360 aa  213  3.9999999999999995e-54  Burkholderia cenocepacia AU 1054  Bacteria  normal  0.0177184  n/a   
 
 
-
 
NC_008542  Bcen2424_0261  chemotaxis-specific methylesterase  38.15 
 
 
360 aa  213  3.9999999999999995e-54  Burkholderia cenocepacia HI2424  Bacteria  normal  0.100544  n/a   
 
 
-
 
NC_010508  Bcenmc03_0243  chemotaxis-specific methylesterase  38.15 
 
 
360 aa  213  3.9999999999999995e-54  Burkholderia cenocepacia MC0-3  Bacteria  normal  0.347664  normal 
 
 
-
 
NC_011145  AnaeK_2679  response regulator receiver modulated CheB methylesterase  45.48 
 
 
342 aa  213  4.9999999999999996e-54  Anaeromyxobacter sp. K  Bacteria  normal  0.204257  n/a   
 
 
-
 
NC_012917  PC1_2607  chemotaxis-specific methylesterase  35.18 
 
 
350 aa  213  5.999999999999999e-54  Pectobacterium carotovorum subsp. carotovorum PC1  Bacteria  normal  0.701564  n/a   
 
 
-
 
NC_011989  Avi_4309  protein-glutamate methylesterase  36.19 
 
 
364 aa  213  5.999999999999999e-54  Agrobacterium vitis S4  Bacteria  normal  n/a   
 
 
-
 
NC_011891  A2cp1_2774  response regulator receiver modulated CheB methylesterase  45.77 
 
 
342 aa  212  7e-54  Anaeromyxobacter dehalogenans 2CP-1  Bacteria  normal  0.0414067  n/a   
 
 
-
 
NC_011138  MADE_00415  chemotaxis-specific methylesterase  35.67 
 
 
348 aa  212  7e-54  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  n/a   
 
 
-
 
NC_006348  BMA2854  chemotaxis-specific methylesterase  37.05 
 
 
364 aa  212  9e-54  Burkholderia mallei ATCC 23344  Bacteria  normal  n/a   
 
 
-
 
NC_007434  BURPS1710b_0071  chemotaxis-specific methylesterase  37.05 
 
 
364 aa  212  9e-54  Burkholderia pseudomallei 1710b  Bacteria  normal  n/a   
 
 
-
 
NC_009076  BURPS1106A_3931  chemotaxis-specific methylesterase  37.05 
 
 
364 aa  212  9e-54  Burkholderia pseudomallei 1106a  Bacteria  normal  n/a   
 
 
-
 
NC_009074  BURPS668_3850  chemotaxis-specific methylesterase  37.05 
 
 
364 aa  212  9e-54  Burkholderia pseudomallei 668  Bacteria  normal  n/a   
 
 
-
 
NC_008785  BMASAVP1_A3429  chemotaxis-specific methylesterase  37.05 
 
 
364 aa  212  9e-54  Burkholderia mallei SAVP1  Bacteria  normal  n/a   
 
 
-
 
NC_008836  BMA10229_A1689  chemotaxis-specific methylesterase  37.05 
 
 
364 aa  212  9e-54  Burkholderia mallei NCTC 10229  Bacteria  normal  0.21493  n/a   
 
 
-
 
NC_010658  SbBS512_E2176  chemotaxis-specific methylesterase  34.44 
 
 
349 aa  211  1e-53  Shigella boydii CDC 3083-94  Bacteria  normal  n/a   
 
 
-
 
NC_003296  RSp1403  chemotaxis-specific methylesterase  37.7 
 
 
381 aa  210  2e-53  Ralstonia solanacearum GMI1000  Bacteria  normal  0.551695  normal  0.0191361 
 
 
-
 
NC_007954  Sden_3301  protein-glutamate methylesterase  39.03 
 
 
358 aa  211  2e-53  Shewanella denitrificans OS217  Bacteria  normal  n/a   
 
 
-
 
NC_007517  Gmet_2418  response regulator receiver (CheY-like) modulated CheB methylesterase  35.04 
 
 
355 aa  210  4e-53  Geobacter metallireducens GS-15  Bacteria  normal  0.033  normal 
 
 
-
 
NC_009483  Gura_2982  response regulator receiver modulated CheB methylesterase  35.56 
 
 
355 aa  209  7e-53  Geobacter uraniireducens Rf4  Bacteria  normal  n/a   
 
 
-
 
NC_007760  Adeh_1383  response regulator receiver (CheY-like) modulated CheB methylesterase  39.5 
 
 
362 aa  209  7e-53  Anaeromyxobacter dehalogenans 2CP-C  Bacteria  normal  n/a   
 
 
-
 
NC_002939  GSU1145  protein-glutamate methylesterase  35.39 
 
 
354 aa  209  8e-53  Geobacter sulfurreducens PCA  Bacteria  decreased coverage  0.00201495  n/a   
 
 
-
 
NC_009831  Ssed_0182  protein-glutamate methylesterase  37.82 
 
 
345 aa  209  8e-53  Shewanella sediminis HAW-EB3  Bacteria  normal  normal 
 
 
-
 
NC_010622  Bphy_2969  chemotaxis-specific methylesterase  37.15 
 
 
367 aa  208  9e-53  Burkholderia phymatum STM815  Bacteria  normal  hitchhiker  0.000910724 
 
 
-
 
NC_011663  Sbal223_2103  response regulator receiver modulated CheB methylesterase  35.31 
 
 
349 aa  208  1e-52  Shewanella baltica OS223  Bacteria  normal  0.262545  normal 
 
 
-
 
NC_011891  A2cp1_2570  response regulator receiver modulated CheB methylesterase  39.33 
 
 
362 aa  208  1e-52  Anaeromyxobacter dehalogenans 2CP-1  Bacteria  normal  n/a   
 
 
-
 
NC_011369  Rleg2_3257  response regulator receiver modulated CheB methylesterase  36.66 
 
 
365 aa  208  1e-52  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  0.238845  normal  0.250549 
 
 
-
 
NC_010717  PXO_04755  chemotaxis-specific methylesterase  38.1 
 
 
379 aa  207  2e-52  Xanthomonas oryzae pv. oryzae PXO99A  Bacteria  normal  n/a   
 
 
-
 
NC_009485  BBta_6730  chemotaxis response regulator protein CheB-glutamate methylesterase  37.91 
 
 
364 aa  207  2e-52  Bradyrhizobium sp. BTAi1  Bacteria  normal  0.324062  normal 
 
 
-
 
NC_010681  Bphyt_3809  chemotaxis-specific methylesterase  37.54 
 
 
362 aa  207  2e-52  Burkholderia phytofirmans PsJN  Bacteria  normal  normal 
 
 
-
 
NC_007575  Suden_0978  response regulator receiver (CheY-like) modulated CheB methylesterase  33.72 
 
 
352 aa  207  3e-52  Sulfurimonas denitrificans DSM 1251  Bacteria  normal  n/a   
 
 
-
 
NC_007908  Rfer_0906  chemotaxis-specific methylesterase  37.57 
 
 
351 aa  207  3e-52  Rhodoferax ferrireducens T118  Bacteria  normal  n/a   
 
 
-
 
NC_011145  AnaeK_2474  response regulator receiver modulated CheB methylesterase  39.33 
 
 
362 aa  206  4e-52  Anaeromyxobacter sp. K  Bacteria  normal  0.0236682  n/a   
 
 
-
 
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