More than 300 homologs were found in PanDaTox collection
for query gene Fnod_1338 on replicon NC_009718
Organism: Fervidobacterium nodosum Rt17-B1



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Replicon accession
Locus tag
Product
% identity
Alignment on query gene
Alignment on homolog gene
Length
Bit score

E-value
Organism name
Kingdom
Plasmid clonability
Plasmid unclonability p-value
Fosmid clonability
Fosmid unclonability p-value
Coverage Plot
PanDaTox homologs
Experimental validation
NC_009718  Fnod_1338  tetrahydrofolate dehydrogenase/cyclohydrolase  100 
 
 		 272 aa  548  1e-155  Fervidobacterium nodosum Rt17-B1  Bacteria  normal  1  n/a   
 
 
-
 
NC_009486  Tpet_1055  methenyltetrahydrofolate cyclohydrolase  54.21 
 
 		 271 aa  293  2e-78  Thermotoga petrophila RKU-1  Bacteria  normal  1  n/a   
 
 
-
 
NC_010483  TRQ2_1057  methenyltetrahydrofolate cyclohydrolase  53.85 
 
 		 271 aa  291  8e-78  Thermotoga sp. RQ2  Bacteria  normal  1  n/a   
 
 
-
 
NC_009616  Tmel_1907  tetrahydrofolate dehydrogenase/cyclohydrolase  50 
 
 		 271 aa  276  2e-73  Thermosipho melanesiensis BI429  Bacteria  normal  1  n/a   
 
 
-
 
NC_010003  Pmob_1757  tetrahydrofolate dehydrogenase/cyclohydrolase  47.13 
 
 		 273 aa  222  4.9999999999999996e-57  Petrotoga mobilis SJ95  Bacteria  normal  1  n/a   
 
 
-
 
NC_008025  Dgeo_0699  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  37.55 
 
 		 289 aa  199  5e-50  Deinococcus geothermalis DSM 11300  Bacteria  normal  0.09451  normal  1 
 
 
-
 
NC_011886  Achl_3465  Methylenetetrahydrofolate dehydrogenase (NADP(+))  43.65 
 
 		 291 aa  188  1e-46  Arthrobacter chlorophenolicus A6  Bacteria  n/a    normal  1 
 
 
-
 
NC_009012  Cthe_1093  methenyltetrahydrofolate cyclohydrolase  40 
 
 		 285 aa  185  8e-46  Clostridium thermocellum ATCC 27405  Bacteria  hitchhiker  0.000000512009  n/a   
 
 
-
 
NC_011832  Mpal_0744  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  38.77 
 
 		 280 aa  184  9e-46  Methanosphaerula palustris E1-9c  Archaea  normal  1  normal  1 
 
 
-
 
NC_010718  Nther_1700  5,10-methylenetetrahydrofolate dehydrogenase (NADP+), Methenyltetrahydrofolate cyclohydrolase  39.44 
 
 		 284 aa  184  1.0000000000000001e-45  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  1  normal  0.335496 
 
 
-
 
NC_013595  Sros_0348  Methylenetetrahydrofolate dehydrogenase (NADP(+))  43.43 
 
 		 279 aa  184  2.0000000000000003e-45  Streptosporangium roseum DSM 43021  Bacteria  normal  1  normal  1 
 
 
-
 
NC_008527  LACR_0921  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  40.14 
 
 		 295 aa  184  2.0000000000000003e-45  Lactococcus lactis subsp. cremoris SK11  Bacteria  unclonable  0.0000659615  n/a   
 
 
-
 
NC_013757  Gobs_2877  Methylenetetrahydrofolate dehydrogenase (NADP(+))  42 
 
 		 279 aa  183  3e-45  Geodermatophilus obscurus DSM 43160  Bacteria  normal  0.0989232  n/a   
 
 
-
 
NC_010814  Glov_0508  Methenyltetrahydrofolate cyclohydrolase  37.99 
 
 		 284 aa  182  5.0000000000000004e-45  Geobacter lovleyi SZ  Bacteria  decreased coverage  0.0000347177  n/a   
 
 
-
 
NC_013926  Aboo_0102  Methylenetetrahydrofolate dehydrogenase (NADP(+))  39.25 
 
 		 272 aa  182  6e-45  Aciduliprofundum boonei T469  Archaea  normal  0.538276  n/a   
 
 
-
 
NC_013411  GYMC61_0247  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  40.59 
 
 		 284 aa  181  8.000000000000001e-45  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_012793  GWCH70_2324  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  38.37 
 
 		 290 aa  181  1e-44  Geobacillus sp. WCH70  Bacteria  hitchhiker  0.0000000808824  n/a   
 
 
-
 
NC_011830  Dhaf_3496  Methylenetetrahydrofolate dehydrogenase (NADP(+))  40.3 
 
 		 284 aa  181  1e-44  Desulfitobacterium hafniense DCB-2  Bacteria  normal  1  n/a   
 
 
-
 
NC_013501  Rmar_0952  Methenyltetrahydrofolate cyclohydrolase  39.31 
 
 		 293 aa  180  2e-44  Rhodothermus marinus DSM 4252  Bacteria  normal  1  n/a   
 
 
-
 
NC_009712  Mboo_2188  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  37.74 
 
 		 278 aa  179  5.999999999999999e-44  Candidatus Methanoregula boonei 6A8  Archaea  normal  0.590033  normal  1 
 
 
-
 
NC_010320  Teth514_1535  methenyltetrahydrofolate cyclohydrolase  37.55 
 
 		 286 aa  177  1e-43  Thermoanaerobacter sp. X514  Bacteria  normal  0.0500443  n/a   
 
 
-
 
NC_009674  Bcer98_2874  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  39.47 
 
 		 286 aa  177  1e-43  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  0.126852  n/a   
 
 
-
 
NC_010184  BcerKBAB4_4033  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  38.35 
 
 		 286 aa  177  2e-43  Bacillus weihenstephanensis KBAB4  Bacteria  normal  0.781388  n/a   
 
 
-
 
NC_009972  Haur_4471  methenyltetrahydrofolate cyclohydrolase  36.94 
 
 		 286 aa  177  2e-43  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  1  n/a   
 
 
-
 
NC_008576  Mmc1_3712  methenyltetrahydrofolate cyclohydrolase  37.99 
 
 		 285 aa  176  4e-43  Magnetococcus sp. MC-1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_013203  Apar_0623  tetrahydrofolate dehydrogenase/cyclohydrolase  38.93 
 
 		 289 aa  176  5e-43  Atopobium parvulum DSM 20469  Bacteria  normal  0.902429  normal  1 
 
 
-
 
NC_005945  BAS4085  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  37.97 
 
 		 286 aa  175  6e-43  Bacillus anthracis str. Sterne  Bacteria  hitchhiker  0.00334729  n/a   
 
 
-
 
NC_007530  GBAA_4405  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  37.97 
 
 		 286 aa  175  6e-43  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  1  n/a   
 
 
-
 
NC_010424  Daud_1022  methenyltetrahydrofolate cyclohydrolase  40.4 
 
 		 287 aa  175  7e-43  Candidatus Desulforudis audaxviator MP104C  Bacteria  normal  0.394203  n/a   
 
 
-
 
NC_010571  Oter_3793  methenyltetrahydrofolate cyclohydrolase  36.84 
 
 		 293 aa  175  7e-43  Opitutus terrae PB90-1  Bacteria  normal  0.0648  normal  0.492726 
 
 
-
 
NC_009051  Memar_1834  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  39.2 
 
 		 283 aa  175  7e-43  Methanoculleus marisnigri JR1  Archaea  normal  1  n/a   
 
 
-
 
NC_005957  BT9727_3923  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  37.97 
 
 		 286 aa  175  9e-43  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  1  n/a   
 
 
-
 
NC_011773  BCAH820_4201  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  37.97 
 
 		 286 aa  175  9e-43  Bacillus cereus AH820  Bacteria  n/a    hitchhiker  3.73931e-16 
 
 
-
 
NC_006274  BCZK3934  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  37.97 
 
 		 286 aa  174  9.999999999999999e-43  Bacillus cereus E33L  Bacteria  normal  0.0428362  n/a   
 
 
-
 
NC_008532  STER_0660  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  37.68 
 
 		 284 aa  174  9.999999999999999e-43  Streptococcus thermophilus LMD-9  Bacteria  normal  1  n/a   
 
 
-
 
NC_013946  Mrub_2371  Methylenetetrahydrofolate dehydrogenase (NADP(+))  36.4 
 
 		 293 aa  174  1.9999999999999998e-42  Meiothermus ruber DSM 1279  Bacteria  normal  0.923762  normal  1 
 
 
-
 
NC_007604  Synpcc7942_0777  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  37.31 
 
 		 289 aa  174  1.9999999999999998e-42  Synechococcus elongatus PCC 7942  Bacteria  normal  0.71594  normal  0.0994354 
 
 
-
 
NC_003909  BCE_4254  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  37.59 
 
 		 286 aa  173  2.9999999999999996e-42  Bacillus cereus ATCC 10987  Bacteria  normal  0.246013  n/a   
 
 
-
 
NC_007413  Ava_2703  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  36.3 
 
 		 299 aa  173  2.9999999999999996e-42  Anabaena variabilis ATCC 29413  Bacteria  hitchhiker  0.00240961  normal  0.676317 
 
 
-
 
NC_011661  Dtur_1636  Methenyltetrahydrofolate cyclohydrolase  39.11 
 
 		 281 aa  173  2.9999999999999996e-42  Dictyoglomus turgidum DSM 6724  Bacteria  normal  1  n/a   
 
 
-
 
NC_011830  Dhaf_0557  Methylenetetrahydrofolate dehydrogenase (NADP(+))  40.14 
 
 		 281 aa  173  2.9999999999999996e-42  Desulfitobacterium hafniense DCB-2  Bacteria  normal  1  n/a   
 
 
-
 
NC_011658  BCAH187_A4311  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  37.59 
 
 		 286 aa  172  3.9999999999999995e-42  Bacillus cereus AH187  Bacteria  normal  0.0277859  n/a   
 
 
-
 
NC_007644  Moth_1516  methenyltetrahydrofolate cyclohydrolase  38.26 
 
 		 280 aa  172  5e-42  Moorella thermoacetica ATCC 39073  Bacteria  normal  1  normal  1 
 
 
-
 
NC_007519  Dde_0296  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  37.31 
 
 		 286 aa  172  5.999999999999999e-42  Desulfovibrio desulfuricans subsp. desulfuricans str. G20  Bacteria  normal  1  n/a   
 
 
-
 
NC_011725  BCB4264_A4291  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  37.22 
 
 		 286 aa  172  5.999999999999999e-42  Bacillus cereus B4264  Bacteria  normal  1  n/a   
 
 
-
 
NC_009714  CHAB381_1036  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  38.79 
 
 		 284 aa  171  7.999999999999999e-42  Campylobacter hominis ATCC BAA-381  Bacteria  normal  1  n/a   
 
 
-
 
NC_010322  PputGB1_2105  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  35.82 
 
 		 303 aa  171  9e-42  Pseudomonas putida GB-1  Bacteria  normal  0.538628  normal  0.603824 
 
 
-
 
NC_013173  Dbac_3223  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  36.7 
 
 		 281 aa  171  1e-41  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  1  n/a   
 
 
-
 
NC_011772  BCG9842_B0943  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  37.22 
 
 		 286 aa  171  1e-41  Bacillus cereus G9842  Bacteria  normal  1  hitchhiker  0.00348961 
 
 
-
 
NC_013131  Caci_8052  Methylenetetrahydrofolate dehydrogenase (NADP(+))  40.08 
 
 		 278 aa  171  1e-41  Catenulispora acidiphila DSM 44928  Bacteria  normal  1  normal  0.592231 
 
 
-
 
NC_010622  Bphy_1475  methenyltetrahydrofolate cyclohydrolase  40.48 
 
 		 285 aa  171  2e-41  Burkholderia phymatum STM815  Bacteria  normal  0.996402  normal  1 
 
 
-
 
NC_004116  SAG0494  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  35.38 
 
 		 284 aa  171  2e-41  Streptococcus agalactiae 2603V/R  Bacteria  normal  1  n/a   
 
 
-
 
NC_009483  Gura_1169  methylenetetrahydrofolate dehydrogenase (NADP(+))  37.88 
 
 		 280 aa  171  2e-41  Geobacter uraniireducens Rf4  Bacteria  hitchhiker  0.00000103166  n/a   
 
 
-
 
NC_008261  CPF_2077  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  37.69 
 
 		 277 aa  171  2e-41  Clostridium perfringens ATCC 13124  Bacteria  normal  0.0318039  n/a   
 
 
-
 
NC_013223  Dret_0218  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  34.42 
 
 		 282 aa  169  3e-41  Desulfohalobium retbaense DSM 5692  Bacteria  normal  0.859941  normal  0.971603 
 
 
-
 
NC_013889  TK90_0603  Methylenetetrahydrofolate dehydrogenase (NADP(+))  36.74 
 
 		 287 aa  169  3e-41  Thioalkalivibrio sp. K90mix  Bacteria  normal  0.399589  normal  0.311345 
 
 
-
 
NC_009455  DehaBAV1_0637  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  38.75 
 
 		 296 aa  170  3e-41  Dehalococcoides sp. BAV1  Bacteria  normal  1  n/a   
 
 
-
 
NC_008340  Mlg_0591  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  35.45 
 
 		 286 aa  169  3e-41  Alkalilimnicola ehrlichii MLHE-1  Bacteria  hitchhiker  0.0000074286  unclonable  2.0108800000000004e-18 
 
 
-
 
NC_011898  Ccel_0604  tetrahydrofolate dehydrogenase/cyclohydrolase  37.96 
 
 		 284 aa  169  4e-41  Clostridium cellulolyticum H10  Bacteria  normal  1  n/a   
 
 
-
 
NC_008554  Sfum_2686  methylenetetrahydrofolate dehydrogenase (NADP(+))  36.16 
 
 		 295 aa  169  4e-41  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  0.204372  normal  0.0139654 
 
 
-
 
NC_009767  Rcas_0735  methenyltetrahydrofolate cyclohydrolase  38.38 
 
 		 288 aa  169  6e-41  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.768044  normal  1 
 
 
-
 
NC_008825  Mpe_A2131  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  36.59 
 
 		 283 aa  169  6e-41  Methylibium petroleiphilum PM1  Bacteria  normal  0.386646  normal  1 
 
 
-
 
NC_008312  Tery_4172  methenyltetrahydrofolate cyclohydrolase  37.65 
 
 		 287 aa  169  6e-41  Trichodesmium erythraeum IMS101  Bacteria  normal  1  normal  0.280923 
 
 
-
 
NC_013093  Amir_4015  Methylenetetrahydrofolate dehydrogenase (NADP(+))  36.6 
 
 		 285 aa  168  7e-41  Actinosynnema mirum DSM 43827  Bacteria  normal  0.305417  n/a   
 
 
-
 
NC_013161  Cyan8802_1617  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  37.31 
 
 		 292 aa  168  7e-41  Cyanothece sp. PCC 8802  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009487  SaurJH9_1123  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  39.18 
 
 		 286 aa  168  8e-41  Staphylococcus aureus subsp. aureus JH9  Bacteria  hitchhiker  0.000919852  n/a   
 
 
-
 
NC_011726  PCC8801_1592  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  37.69 
 
 		 292 aa  168  8e-41  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_009632  SaurJH1_1145  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  39.18 
 
 		 286 aa  168  8e-41  Staphylococcus aureus subsp. aureus JH1  Bacteria  hitchhiker  0.00105319  n/a   
 
 
-
 
NC_011831  Cagg_0060  Methenyltetrahydrofolate cyclohydrolase  35.53 
 
 		 285 aa  167  1e-40  Chloroflexus aggregans DSM 9485  Bacteria  normal  1  normal  0.296483 
 
 
-
 
NC_009338  Mflv_4879  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  34.21 
 
 		 286 aa  167  2e-40  Mycobacterium gilvum PYR-GCK  Bacteria  normal  1  normal  0.0903189 
 
 
-
 
NC_002967  TDE0013  methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase  34.85 
 
 		 293 aa  167  2e-40  Treponema denticola ATCC 35405  Bacteria  normal  1  n/a   
 
 
-
 
NC_007347  Reut_A1299  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  36.68 
 
 		 283 aa  167  2e-40  Ralstonia eutropha JMP134  Bacteria  normal  0.293991  n/a   
 
 
-
 
NC_014150  Bmur_1444  Methylenetetrahydrofolate dehydrogenase (NADP(+))  39.48 
 
 		 278 aa  167  2e-40  Brachyspira murdochii DSM 12563  Bacteria  normal  1  n/a   
 
 
-
 
NC_008726  Mvan_1550  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  34.98 
 
 		 288 aa  167  2e-40  Mycobacterium vanbaalenii PYR-1  Bacteria  normal  1  normal  0.103372 
 
 
-
 
NC_009921  Franean1_4183  methylenetetrahydrofolate dehydrogenase (NADP(+))  42.15 
 
 		 275 aa  167  2e-40  Frankia sp. EAN1pec  Bacteria  normal  0.0949993  normal  0.629252 
 
 
-
 
NC_011059  Paes_1178  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  36.81 
 
 		 295 aa  167  2e-40  Prosthecochloris aestuarii DSM 271  Bacteria  normal  1  normal  0.545639 
 
 
-
 
NC_011884  Cyan7425_0973  Methylenetetrahydrofolate dehydrogenase (NADP(+))  36.3 
 
 		 293 aa  167  2e-40  Cyanothece sp. PCC 7425  Bacteria  normal  0.150063  normal  0.215441 
 
 
-
 
NC_010803  Clim_1112  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  38.71 
 
 		 296 aa  167  2e-40  Chlorobium limicola DSM 245  Bacteria  normal  1  n/a   
 
 
-
 
NC_011729  PCC7424_0607  Methenyltetrahydrofolate cyclohydrolase  36.6 
 
 		 301 aa  166  4e-40  Cyanothece sp. PCC 7424  Bacteria  n/a    normal  1 
 
 
-
 
NC_008262  CPR_1791  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  36.92 
 
 		 277 aa  166  4e-40  Clostridium perfringens SM101  Bacteria  normal  0.0128515  n/a   
 
 
-
 
NC_007512  Plut_0927  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  39.29 
 
 		 307 aa  166  5e-40  Chlorobium luteolum DSM 273  Bacteria  normal  1  normal  1 
 
 
-
 
NC_012034  Athe_0982  Methenyltetrahydrofolate cyclohydrolase  39.47 
 
 		 289 aa  166  5e-40  Anaerocellum thermophilum DSM 6725  Bacteria  hitchhiker  0.000669614  n/a   
 
 
-
 
NC_009565  TBFG_13392  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  35.11 
 
 		 281 aa  165  5.9999999999999996e-40  Mycobacterium tuberculosis F11  Bacteria  normal  1  normal  0.0406677 
 
 
-
 
NC_013552  DhcVS_606  methylenetetrahydrofolate dehydrogenase (NADP+)/methenyltetrahydrofolate cyclohydrolase  38.6 
 
 		 296 aa  165  5.9999999999999996e-40  Dehalococcoides sp. VS  Bacteria  normal  1  n/a   
 
 
-
 
NC_010424  Daud_0103  methenyltetrahydrofolate cyclohydrolase  37.74 
 
 		 294 aa  165  6.9999999999999995e-40  Candidatus Desulforudis audaxviator MP104C  Bacteria  normal  1  n/a   
 
 
-
 
NC_002936  DET0668  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  38.6 
 
 		 296 aa  165  8e-40  Dehalococcoides ethenogenes 195  Bacteria  normal  1  n/a   
 
 
-
 
NC_002936  DET0702  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  38.6 
 
 		 296 aa  165  8e-40  Dehalococcoides ethenogenes 195  Bacteria  normal  1  n/a   
 
 
-
 
NC_013739  Cwoe_3588  Methylenetetrahydrofolate dehydrogenase (NADP(+))  44.78 
 
 		 283 aa  165  8e-40  Conexibacter woesei DSM 14684  Bacteria  normal  0.24704  normal  0.653023 
 
 
-
 
NC_009253  Dred_1073  methylenetetrahydrofolate dehydrogenase (NADP(+))  35.16 
 
 		 284 aa  165  9e-40  Desulfotomaculum reducens MI-1  Bacteria  normal  0.174822  n/a   
 
 
-
 
NC_011146  Gbem_1497  tetrahydrofolate dehydrogenase/cyclohydrolase  36.9 
 
 		 281 aa  165  9e-40  Geobacter bemidjiensis Bem  Bacteria  hitchhiker  0.0000244416  n/a   
 
 
-
 
NC_012918  GM21_2719  Methylenetetrahydrofolate dehydrogenase (NADP(+))  36.9 
 
 		 281 aa  164  1.0000000000000001e-39  Geobacter sp. M21  Bacteria  n/a    normal  1 
 
 
-
 
NC_009379  Pnuc_0731  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  38.74 
 
 		 284 aa  164  1.0000000000000001e-39  Polynucleobacter necessarius subsp. asymbioticus QLW-P1DMWA-1  Bacteria  normal  0.945506  n/a   
 
 
-
 
NC_007777  Francci3_1492  methenyltetrahydrofolate cyclohydrolase  39.15 
 
 		 276 aa  164  1.0000000000000001e-39  Frankia sp. CcI3  Bacteria  normal  0.310861  normal  1 
 
 
-
 
NC_007794  Saro_3300  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  39.38 
 
 		 297 aa  164  1.0000000000000001e-39  Novosphingobium aromaticivorans DSM 12444  Bacteria  normal  1  n/a   
 
 
-
 
NC_007908  Rfer_2209  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  37.68 
 
 		 287 aa  164  1.0000000000000001e-39  Rhodoferax ferrireducens T118  Bacteria  normal  0.699057  n/a   
 
 
-
 
NC_013204  Elen_2861  tetrahydrofolate dehydrogenase/cyclohydrolase  37.73 
 
 		 289 aa  164  1.0000000000000001e-39  Eggerthella lenta DSM 2243  Bacteria  normal  1  normal  1 
 
 
-
 
NC_014248  Aazo_1506  methenyltetrahydrofolate cyclohydrolase  35.34 
 
 		 294 aa  164  1.0000000000000001e-39  'Nostoc azollae' 0708  Bacteria  normal  1  n/a   
 
 
-
 
NC_013515  Smon_0375  Methylenetetrahydrofolate dehydrogenase (NADP(+))  36.29 
 
 		 285 aa  164  1.0000000000000001e-39  Streptobacillus moniliformis DSM 12112  Bacteria  n/a    n/a   
 
 
-
 
NC_002939  GSU0862  folD bifunctional protein  34.93 
 
 		 285 aa  164  2.0000000000000002e-39  Geobacter sulfurreducens PCA  Bacteria  normal  1  n/a   
 
 
-
 
NC_013165  Shel_20930  methenyltetrahydrofolate cyclohydrolase /5,10-methylenetetrahydrofolate dehydrogenase (NADP+)  35.74 
 
 		 284 aa  164  2.0000000000000002e-39  Slackia heliotrinireducens DSM 20476  Bacteria  normal  1  normal  1 
 
 
-
 
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