More than 300 homologs were found in PanDaTox collection
for query gene Bmur_1444 on replicon NC_014150
Organism: Brachyspira murdochii DSM 12563



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Replicon accession
Locus tag
Product
% identity
Alignment on query gene
Alignment on homolog gene
Length
Bit score

E-value
Organism name
Kingdom
Plasmid clonability
Plasmid unclonability p-value
Fosmid clonability
Fosmid unclonability p-value
Coverage Plot
PanDaTox homologs
Experimental validation
NC_014150  Bmur_1444  Methylenetetrahydrofolate dehydrogenase (NADP(+))  100 
 
 		 278 aa  561  1.0000000000000001e-159  Brachyspira murdochii DSM 12563  Bacteria  normal  1  n/a   
 
 
-
 
NC_009012  Cthe_1093  methenyltetrahydrofolate cyclohydrolase  47.27 
 
 		 285 aa  261  1e-68  Clostridium thermocellum ATCC 27405  Bacteria  hitchhiker  0.000000512009  n/a   
 
 
-
 
NC_007644  Moth_1516  methenyltetrahydrofolate cyclohydrolase  43.84 
 
 		 280 aa  256  2e-67  Moorella thermoacetica ATCC 39073  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009715  CCV52592_0799  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  45.39 
 
 		 288 aa  252  4.0000000000000004e-66  Campylobacter curvus 525.92  Bacteria  normal  1  n/a   
 
 
-
 
NC_007604  Synpcc7942_0777  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  42.86 
 
 		 289 aa  248  7e-65  Synechococcus elongatus PCC 7942  Bacteria  normal  0.71594  normal  0.0994354 
 
 
-
 
NC_008576  Mmc1_3712  methenyltetrahydrofolate cyclohydrolase  42.35 
 
 		 285 aa  248  1e-64  Magnetococcus sp. MC-1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009802  CCC13826_0832  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  45.02 
 
 		 283 aa  247  1e-64  Campylobacter concisus 13826  Bacteria  normal  0.048214  n/a   
 
 
-
 
NC_011898  Ccel_0604  tetrahydrofolate dehydrogenase/cyclohydrolase  45.72 
 
 		 284 aa  248  1e-64  Clostridium cellulolyticum H10  Bacteria  normal  1  n/a   
 
 
-
 
NC_008340  Mlg_0591  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  40.81 
 
 		 286 aa  243  3e-63  Alkalilimnicola ehrlichii MLHE-1  Bacteria  hitchhiker  0.0000074286  unclonable  2.0108800000000004e-18 
 
 
-
 
NC_012793  GWCH70_2324  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  43.17 
 
 		 290 aa  242  6e-63  Geobacillus sp. WCH70  Bacteria  hitchhiker  0.0000000808824  n/a   
 
 
-
 
NC_009714  CHAB381_1036  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  44.28 
 
 		 284 aa  240  2e-62  Campylobacter hominis ATCC BAA-381  Bacteria  normal  1  n/a   
 
 
-
 
NC_010320  Teth514_1535  methenyltetrahydrofolate cyclohydrolase  44.24 
 
 		 286 aa  239  5e-62  Thermoanaerobacter sp. X514  Bacteria  normal  0.0500443  n/a   
 
 
-
 
NC_009674  Bcer98_2874  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  43.32 
 
 		 286 aa  238  9e-62  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  0.126852  n/a   
 
 
-
 
NC_002967  TDE0013  methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase  42.01 
 
 		 293 aa  237  2e-61  Treponema denticola ATCC 35405  Bacteria  normal  1  n/a   
 
 
-
 
NC_009487  SaurJH9_1123  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  40.71 
 
 		 286 aa  237  2e-61  Staphylococcus aureus subsp. aureus JH9  Bacteria  hitchhiker  0.000919852  n/a   
 
 
-
 
NC_004311  BRA0781  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  43.26 
 
 		 299 aa  237  2e-61  Brucella suis 1330  Bacteria  normal  1  n/a   
 
 
-
 
NC_009632  SaurJH1_1145  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  40.71 
 
 		 286 aa  237  2e-61  Staphylococcus aureus subsp. aureus JH1  Bacteria  hitchhiker  0.00105319  n/a   
 
 
-
 
NC_009504  BOV_A0731  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  43.26 
 
 		 299 aa  237  2e-61  Brucella ovis ATCC 25840  Bacteria  normal  1  n/a   
 
 
-
 
NC_009668  Oant_3959  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  43.62 
 
 		 299 aa  236  3e-61  Ochrobactrum anthropi ATCC 49188  Bacteria  normal  0.791035  n/a   
 
 
-
 
NC_010814  Glov_0508  Methenyltetrahydrofolate cyclohydrolase  42.8 
 
 		 284 aa  236  3e-61  Geobacter lovleyi SZ  Bacteria  decreased coverage  0.0000347177  n/a   
 
 
-
 
NC_008527  LACR_0921  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  42.07 
 
 		 295 aa  236  4e-61  Lactococcus lactis subsp. cremoris SK11  Bacteria  unclonable  0.0000659615  n/a   
 
 
-
 
NC_011729  PCC7424_0607  Methenyltetrahydrofolate cyclohydrolase  42.7 
 
 		 301 aa  235  6e-61  Cyanothece sp. PCC 7424  Bacteria  n/a    normal  1 
 
 
-
 
NC_002976  SERP0648  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  42.55 
 
 		 286 aa  235  7e-61  Staphylococcus epidermidis RP62A  Bacteria  normal  1  n/a   
 
 
-
 
NC_012034  Athe_0982  Methenyltetrahydrofolate cyclohydrolase  44.06 
 
 		 289 aa  234  8e-61  Anaerocellum thermophilum DSM 6725  Bacteria  hitchhiker  0.000669614  n/a   
 
 
-
 
NC_008530  LGAS_0751  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  42.03 
 
 		 282 aa  234  1.0000000000000001e-60  Lactobacillus gasseri ATCC 33323  Bacteria  normal  0.0811051  hitchhiker  0.000994915 
 
 
-
 
NC_005945  BAS4085  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  42.24 
 
 		 286 aa  233  2.0000000000000002e-60  Bacillus anthracis str. Sterne  Bacteria  hitchhiker  0.00334729  n/a   
 
 
-
 
NC_006274  BCZK3934  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  42.24 
 
 		 286 aa  233  2.0000000000000002e-60  Bacillus cereus E33L  Bacteria  normal  0.0428362  n/a   
 
 
-
 
NC_007530  GBAA_4405  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  42.24 
 
 		 286 aa  233  2.0000000000000002e-60  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  1  n/a   
 
 
-
 
NC_010184  BcerKBAB4_4033  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  42.24 
 
 		 286 aa  233  3e-60  Bacillus weihenstephanensis KBAB4  Bacteria  normal  0.781388  n/a   
 
 
-
 
NC_008599  CFF8240_1174  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  42.44 
 
 		 283 aa  233  3e-60  Campylobacter fetus subsp. fetus 82-40  Bacteria  normal  0.840508  n/a   
 
 
-
 
NC_009483  Gura_1169  methylenetetrahydrofolate dehydrogenase (NADP(+))  41.67 
 
 		 280 aa  232  5e-60  Geobacter uraniireducens Rf4  Bacteria  hitchhiker  0.00000103166  n/a   
 
 
-
 
NC_010424  Daud_0103  methenyltetrahydrofolate cyclohydrolase  41.18 
 
 		 294 aa  232  5e-60  Candidatus Desulforudis audaxviator MP104C  Bacteria  normal  1  n/a   
 
 
-
 
NC_011725  BCB4264_A4291  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  42.24 
 
 		 286 aa  232  6e-60  Bacillus cereus B4264  Bacteria  normal  1  n/a   
 
 
-
 
NC_011772  BCG9842_B0943  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  42.24 
 
 		 286 aa  232  6e-60  Bacillus cereus G9842  Bacteria  normal  1  hitchhiker  0.00348961 
 
 
-
 
NC_005957  BT9727_3923  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  41.88 
 
 		 286 aa  231  7.000000000000001e-60  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  1  n/a   
 
 
-
 
NC_011773  BCAH820_4201  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  41.88 
 
 		 286 aa  231  7.000000000000001e-60  Bacillus cereus AH820  Bacteria  n/a    hitchhiker  3.73931e-16 
 
 
-
 
NC_011830  Dhaf_3496  Methylenetetrahydrofolate dehydrogenase (NADP(+))  42.8 
 
 		 284 aa  231  9e-60  Desulfitobacterium hafniense DCB-2  Bacteria  normal  1  n/a   
 
 
-
 
NC_009455  DehaBAV1_0637  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  43.36 
 
 		 296 aa  230  2e-59  Dehalococcoides sp. BAV1  Bacteria  normal  1  n/a   
 
 
-
 
NC_007517  Gmet_1162  methenyltetrahydrofolate cyclohydrolase  40.94 
 
 		 285 aa  230  2e-59  Geobacter metallireducens GS-15  Bacteria  hitchhiker  0.00000000377219  hitchhiker  0.00798692 
 
 
-
 
NC_008254  Meso_0152  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  40.48 
 
 		 298 aa  230  2e-59  Chelativorans sp. BNC1  Bacteria  normal  0.386  n/a   
 
 
-
 
NC_011658  BCAH187_A4311  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  41.52 
 
 		 286 aa  229  3e-59  Bacillus cereus AH187  Bacteria  normal  0.0277859  n/a   
 
 
-
 
NC_003909  BCE_4254  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  41.16 
 
 		 286 aa  229  4e-59  Bacillus cereus ATCC 10987  Bacteria  normal  0.246013  n/a   
 
 
-
 
NC_007493  RSP_0661  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  39.22 
 
 		 296 aa  229  4e-59  Rhodobacter sphaeroides 2.4.1  Bacteria  normal  1  n/a   
 
 
-
 
NC_009049  Rsph17029_2314  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  39.22 
 
 		 296 aa  229  5e-59  Rhodobacter sphaeroides ATCC 17029  Bacteria  normal  1  normal  0.206347 
 
 
-
 
NC_004116  SAG0494  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  40.74 
 
 		 284 aa  228  9e-59  Streptococcus agalactiae 2603V/R  Bacteria  normal  1  n/a   
 
 
-
 
NC_008309  HS_1221  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  42.65 
 
 		 282 aa  228  1e-58  Haemophilus somnus 129PT  Bacteria  decreased coverage  0.00020406  n/a   
 
 
-
 
NC_008686  Pden_2614  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  38.03 
 
 		 298 aa  226  2e-58  Paracoccus denitrificans PD1222  Bacteria  normal  0.508138  normal  1 
 
 
-
 
NC_009831  Ssed_1539  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  40.5 
 
 		 284 aa  227  2e-58  Shewanella sediminis HAW-EB3  Bacteria  hitchhiker  0.00454653  hitchhiker  0.000334608 
 
 
-
 
NC_007984  BCI_0122  5,10-methylene-tetrahydrofolate dehydrogenase  42.65 
 
 		 285 aa  227  2e-58  Baumannia cicadellinicola str. Hc (Homalodisca coagulata)  Bacteria  normal  0.0634333  n/a   
 
 
-
 
NC_009428  Rsph17025_0571  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  39.93 
 
 		 296 aa  227  2e-58  Rhodobacter sphaeroides ATCC 17025  Bacteria  normal  1  normal  1 
 
 
-
 
NC_008688  Pden_4905  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  38.03 
 
 		 302 aa  226  3e-58  Paracoccus denitrificans PD1222  Bacteria  normal  1  normal  0.171078 
 
 
-
 
NC_010718  Nther_1700  5,10-methylenetetrahydrofolate dehydrogenase (NADP+), Methenyltetrahydrofolate cyclohydrolase  39.43 
 
 		 284 aa  226  4e-58  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  1  normal  0.335496 
 
 
-
 
NC_012880  Dd703_2658  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  38.93 
 
 		 289 aa  226  4e-58  Dickeya dadantii Ech703  Bacteria  normal  0.241402  n/a   
 
 
-
 
NC_012850  Rleg_0385  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  40.07 
 
 		 299 aa  226  4e-58  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  1  normal  1 
 
 
-
 
NC_002936  DET0668  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  42.66 
 
 		 296 aa  225  5.0000000000000005e-58  Dehalococcoides ethenogenes 195  Bacteria  normal  1  n/a   
 
 
-
 
NC_002936  DET0702  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  42.66 
 
 		 296 aa  225  5.0000000000000005e-58  Dehalococcoides ethenogenes 195  Bacteria  normal  1  n/a   
 
 
-
 
NC_013552  DhcVS_606  methylenetetrahydrofolate dehydrogenase (NADP+)/methenyltetrahydrofolate cyclohydrolase  42.66 
 
 		 296 aa  225  5.0000000000000005e-58  Dehalococcoides sp. VS  Bacteria  normal  1  n/a   
 
 
-
 
NC_002978  WD0555  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  41.61 
 
 		 292 aa  224  8e-58  Wolbachia endosymbiont of Drosophila melanogaster  Bacteria  normal  0.752061  n/a   
 
 
-
 
NC_011138  MADE_02962  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  38.93 
 
 		 284 aa  224  8e-58  Alteromonas macleodii 'Deep ecotype'  Bacteria  hitchhiker  0.00178937  n/a   
 
 
-
 
NC_007760  Adeh_1247  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  40.79 
 
 		 282 aa  224  1e-57  Anaeromyxobacter dehalogenans 2CP-C  Bacteria  normal  1  n/a   
 
 
-
 
NC_009439  Pmen_3458  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  40.15 
 
 		 303 aa  224  2e-57  Pseudomonas mendocina ymp  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009636  Smed_0290  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  38.54 
 
 		 299 aa  224  2e-57  Sinorhizobium medicae WSM419  Bacteria  normal  0.154774  normal  1 
 
 
-
 
NC_012912  Dd1591_1250  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  38.93 
 
 		 289 aa  223  2e-57  Dickeya zeae Ech1591  Bacteria  normal  0.0185449  n/a   
 
 
-
 
NC_011146  Gbem_1497  tetrahydrofolate dehydrogenase/cyclohydrolase  39.86 
 
 		 281 aa  224  2e-57  Geobacter bemidjiensis Bem  Bacteria  hitchhiker  0.0000244416  n/a   
 
 
-
 
NC_008044  TM1040_2356  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  40.28 
 
 		 300 aa  223  2e-57  Ruegeria sp. TM1040  Bacteria  normal  1  normal  0.531119 
 
 
-
 
NC_008148  Rxyl_0827  methenyltetrahydrofolate cyclohydrolase  39.11 
 
 		 284 aa  224  2e-57  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  0.997708  n/a   
 
 
-
 
NC_014148  Plim_3436  Methylenetetrahydrofolate dehydrogenase (NADP(+))  40.58 
 
 		 291 aa  223  3e-57  Planctomyces limnophilus DSM 3776  Bacteria  normal  1  n/a   
 
 
-
 
NC_010338  Caul_1714  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  36.43 
 
 		 298 aa  223  3e-57  Caulobacter sp. K31  Bacteria  normal  0.0298416  normal  0.218409 
 
 
-
 
NC_011369  Rleg2_1627  Methenyltetrahydrofolate cyclohydrolase  39.01 
 
 		 298 aa  223  3e-57  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  0.189064  normal  0.743111 
 
 
-
 
NC_011145  AnaeK_2618  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  40.43 
 
 		 282 aa  223  3e-57  Anaeromyxobacter sp. K  Bacteria  normal  0.442042  n/a   
 
 
-
 
NC_004347  SO_1792  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  40 
 
 		 284 aa  222  4e-57  Shewanella oneidensis MR-1  Bacteria  n/a    n/a   
 
 
-
 
NC_009379  Pnuc_0731  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  43.91 
 
 		 284 aa  222  4e-57  Polynucleobacter necessarius subsp. asymbioticus QLW-P1DMWA-1  Bacteria  normal  0.945506  n/a   
 
 
-
 
NC_012918  GM21_2719  Methylenetetrahydrofolate dehydrogenase (NADP(+))  39.86 
 
 		 281 aa  223  4e-57  Geobacter sp. M21  Bacteria  n/a    normal  1 
 
 
-
 
NC_008322  Shewmr7_2565  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  40.71 
 
 		 284 aa  222  4e-57  Shewanella sp. MR-7  Bacteria  unclonable  0.00000214044  normal  0.0576142 
 
 
-
 
NC_013501  Rmar_0952  Methenyltetrahydrofolate cyclohydrolase  39.3 
 
 		 293 aa  222  4.9999999999999996e-57  Rhodothermus marinus DSM 4252  Bacteria  normal  1  n/a   
 
 
-
 
NC_011891  A2cp1_2712  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  40.07 
 
 		 282 aa  222  7e-57  Anaeromyxobacter dehalogenans 2CP-1  Bacteria  normal  1  n/a   
 
 
-
 
NC_008700  Sama_1222  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  39.78 
 
 		 284 aa  221  7e-57  Shewanella amazonensis SB2B  Bacteria  hitchhiker  0.0000458246  normal  1 
 
 
-
 
NC_011884  Cyan7425_0973  Methylenetetrahydrofolate dehydrogenase (NADP(+))  38.95 
 
 		 293 aa  221  7e-57  Cyanothece sp. PCC 7425  Bacteria  normal  0.150063  normal  0.215441 
 
 
-
 
NC_007794  Saro_3300  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  38.25 
 
 		 297 aa  221  7e-57  Novosphingobium aromaticivorans DSM 12444  Bacteria  normal  1  n/a   
 
 
-
 
NC_013739  Cwoe_3588  Methylenetetrahydrofolate dehydrogenase (NADP(+))  37.36 
 
 		 283 aa  222  7e-57  Conexibacter woesei DSM 14684  Bacteria  normal  0.24704  normal  0.653023 
 
 
-
 
CP001509  ECD_00479  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  39.29 
 
 		 288 aa  221  8e-57  Escherichia coli BL21(DE3)  Bacteria  normal  0.382611  n/a   
 
 
-
 
CP001637  EcDH1_3084  Methenyltetrahydrofolate cyclohydrolase  39.29 
 
 		 288 aa  221  8e-57  Escherichia coli DH1  Bacteria  hitchhiker  0.00232553  n/a   
 
 
-
 
NC_009800  EcHS_A0603  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  39.29 
 
 		 288 aa  221  8e-57  Escherichia coli HS  Bacteria  hitchhiker  0.00000146653  n/a   
 
 
-
 
NC_012892  B21_00484  hypothetical protein  39.29 
 
 		 288 aa  221  8e-57  Escherichia coli BL21  Bacteria  normal  0.502644  n/a   
 
 
-
 
NC_009832  Spro_1168  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  37.37 
 
 		 288 aa  221  8e-57  Serratia proteamaculans 568  Bacteria  normal  0.0275067  normal  0.0260565 
 
 
-
 
NC_009801  EcE24377A_0570  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  39.29 
 
 		 288 aa  221  8e-57  Escherichia coli E24377A  Bacteria  hitchhiker  0.000783688  n/a   
 
 
-
 
NC_011353  ECH74115_0630  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  39.29 
 
 		 288 aa  221  8e-57  Escherichia coli O157:H7 str. EC4115  Bacteria  normal  0.0455226  normal  0.700436 
 
 
-
 
NC_010498  EcSMS35_0574  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  39.29 
 
 		 288 aa  221  8e-57  Escherichia coli SMS-3-5  Bacteria  normal  0.0921889  normal  1 
 
 
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NC_009675  Anae109_2520  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  39.35 
 
 		 281 aa  221  8e-57  Anaeromyxobacter sp. Fw109-5  Bacteria  normal  0.412381  normal  0.0135619 
 
 
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NC_010658  SbBS512_E0445  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  39.29 
 
 		 288 aa  221  8e-57  Shigella boydii CDC 3083-94  Bacteria  hitchhiker  0.0000211626  n/a   
 
 
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NC_010468  EcolC_3093  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  39.29 
 
 		 288 aa  221  8e-57  Escherichia coli ATCC 8739  Bacteria  normal  0.0976764  normal  1 
 
 
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NC_010655  Amuc_1641  Methenyltetrahydrofolate cyclohydrolase  39.29 
 
 		 291 aa  221  8e-57  Akkermansia muciniphila ATCC BAA-835  Bacteria  normal  1  normal  0.794405 
 
 
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NC_011366  Rleg2_5643  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  39.02 
 
 		 299 aa  221  9.999999999999999e-57  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  0.667833  normal  1 
 
 
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NC_010506  Swoo_3115  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  39.43 
 
 		 286 aa  221  9.999999999999999e-57  Shewanella woodyi ATCC 51908  Bacteria  hitchhiker  0.00000143268  decreased coverage  0.000000300932 
 
 
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NC_008577  Shewana3_2663  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  40.36 
 
 		 284 aa  221  9.999999999999999e-57  Shewanella sp. ANA-3  Bacteria  hitchhiker  0.00000544114  normal  0.482373 
 
 
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NC_013161  Cyan8802_1617  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  39.44 
 
 		 292 aa  221  9.999999999999999e-57  Cyanothece sp. PCC 8802  Bacteria  normal  1  normal  1 
 
 
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NC_009368  OSTLU_27405  predicted protein  39.86 
 
 		 300 aa  221  9.999999999999999e-57  Ostreococcus lucimarinus CCE9901  Eukaryota  normal  1  normal  0.179734 
 
 
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NC_008321  Shewmr4_2497  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  40.36 
 
 		 284 aa  221  9.999999999999999e-57  Shewanella sp. MR-4  Bacteria  decreased coverage  0.000000101338  normal  0.0187987 
 
 
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NC_008789  Hhal_0610  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  40.07 
 
 		 290 aa  220  1.9999999999999999e-56  Halorhodospira halophila SL1  Bacteria  normal  0.565768  n/a   
 
 
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NC_009436  Ent638_0986  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  38.08 
 
 		 288 aa  220  1.9999999999999999e-56  Enterobacter sp. 638  Bacteria  normal  0.276679  normal  0.0778918 
 
 
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