More than 300 homologs were found in PanDaTox collection
for query gene Pcal_1897 on replicon NC_009073
Organism: Pyrobaculum calidifontis JCM 11548



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_009073  Pcal_1897  methenyltetrahydrofolate cyclohydrolase  100 
 
 
308 aa  609  1e-173  Pyrobaculum calidifontis JCM 11548  Archaea  n/a    normal 
 
 
-
 
NC_009376  Pars_2192  tetrahydrofolate dehydrogenase/cyclohydrolase  77.7 
 
 
311 aa  469  1.0000000000000001e-131  Pyrobaculum arsenaticum DSM 13514  Archaea  normal  normal 
 
 
-
 
NC_008701  Pisl_0104  tetrahydrofolate dehydrogenase/cyclohydrolase  73.44 
 
 
311 aa  432  1e-120  Pyrobaculum islandicum DSM 4184  Archaea  normal  0.0409732  normal 
 
 
-
 
NC_010525  Tneu_1909  methylenetetrahydrofolate dehydrogenase (NADP(+))  75.16 
 
 
311 aa  419  1e-116  Thermoproteus neutrophilus V24Sta  Archaea  decreased coverage  0.000677718  normal  0.128415 
 
 
-
 
NC_012034  Athe_0982  Methenyltetrahydrofolate cyclohydrolase  38.57 
 
 
289 aa  195  8.000000000000001e-49  Anaerocellum thermophilum DSM 6725  Bacteria  hitchhiker  0.000669614  n/a   
 
 
-
 
NC_012029  Hlac_1624  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  42.19 
 
 
307 aa  192  7e-48  Halorubrum lacusprofundi ATCC 49239  Archaea  normal  normal 
 
 
-
 
NC_012039  Cla_0581  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  38.44 
 
 
298 aa  191  1e-47  Campylobacter lari RM2100  Bacteria  normal  0.388564  n/a   
 
 
-
 
NC_009714  CHAB381_1036  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  37.5 
 
 
284 aa  188  1e-46  Campylobacter hominis ATCC BAA-381  Bacteria  normal  n/a   
 
 
-
 
NC_011126  HY04AAS1_0893  Methenyltetrahydrofolate cyclohydrolase  38.57 
 
 
278 aa  185  9e-46  Hydrogenobaculum sp. Y04AAS1  Bacteria  normal  n/a   
 
 
-
 
NC_013922  Nmag_2300  Methenyltetrahydrofolate cyclohydrolase  41.53 
 
 
297 aa  184  1.0000000000000001e-45  Natrialba magadii ATCC 43099  Archaea  normal  n/a   
 
 
-
 
NC_013202  Hmuk_2214  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  39.33 
 
 
297 aa  184  2.0000000000000003e-45  Halomicrobium mukohataei DSM 12286  Archaea  normal  0.621742  normal  0.605059 
 
 
-
 
NC_013158  Huta_2943  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  39.67 
 
 
297 aa  183  3e-45  Halorhabdus utahensis DSM 12940  Archaea  normal  0.420051  n/a   
 
 
-
 
NC_003912  CJE0942  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  37.29 
 
 
282 aa  182  7e-45  Campylobacter jejuni RM1221  Bacteria  normal  n/a   
 
 
-
 
NC_009715  CCV52592_0799  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  35.23 
 
 
288 aa  182  8.000000000000001e-45  Campylobacter curvus 525.92  Bacteria  normal  n/a   
 
 
-
 
NC_013517  Sterm_1178  Methylenetetrahydrofolate dehydrogenase (NADP(+))  38.8 
 
 
285 aa  182  9.000000000000001e-45  Sebaldella termitidis ATCC 33386  Bacteria  hitchhiker  0.0000000836934  n/a   
 
 
-
 
NC_010424  Daud_0103  methenyltetrahydrofolate cyclohydrolase  39.12 
 
 
294 aa  181  1e-44  Candidatus Desulforudis audaxviator MP104C  Bacteria  normal  n/a   
 
 
-
 
NC_008787  CJJ81176_0871  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  37.29 
 
 
282 aa  181  2e-44  Campylobacter jejuni subsp. jejuni 81-176  Bacteria  normal  0.0134315  n/a   
 
 
-
 
NC_007644  Moth_1516  methenyltetrahydrofolate cyclohydrolase  38.91 
 
 
280 aa  180  2e-44  Moorella thermoacetica ATCC 39073  Bacteria  normal  normal 
 
 
-
 
NC_013512  Sdel_0845  Methylenetetrahydrofolate dehydrogenase (NADP(+))  36.27 
 
 
281 aa  179  7e-44  Sulfurospirillum deleyianum DSM 6946  Bacteria  normal  n/a   
 
 
-
 
NC_013743  Htur_1699  Methenyltetrahydrofolate cyclohydrolase  40.53 
 
 
297 aa  178  8e-44  Haloterrigena turkmenica DSM 5511  Archaea  n/a    n/a   
 
 
-
 
NC_009707  JJD26997_1004  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  36.95 
 
 
282 aa  178  1e-43  Campylobacter jejuni subsp. doylei 269.97  Bacteria  normal  0.226194  n/a   
 
 
-
 
NC_009487  SaurJH9_1123  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  35.74 
 
 
286 aa  176  3e-43  Staphylococcus aureus subsp. aureus JH9  Bacteria  hitchhiker  0.000919852  n/a   
 
 
-
 
NC_009632  SaurJH1_1145  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  35.74 
 
 
286 aa  176  3e-43  Staphylococcus aureus subsp. aureus JH1  Bacteria  hitchhiker  0.00105319  n/a   
 
 
-
 
NC_010831  Cphamn1_1442  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  35.69 
 
 
298 aa  177  3e-43  Chlorobium phaeobacteroides BS1  Bacteria  normal  0.56836  normal 
 
 
-
 
NC_007512  Plut_0927  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  37.87 
 
 
307 aa  176  4e-43  Chlorobium luteolum DSM 273  Bacteria  normal  normal 
 
 
-
 
NC_009012  Cthe_1093  methenyltetrahydrofolate cyclohydrolase  36.18 
 
 
285 aa  176  4e-43  Clostridium thermocellum ATCC 27405  Bacteria  hitchhiker  0.000000512009  n/a   
 
 
-
 
NC_007514  Cag_0779  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  36.88 
 
 
295 aa  176  5e-43  Chlorobium chlorochromatii CaD3  Bacteria  normal  n/a   
 
 
-
 
NC_009802  CCC13826_0832  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  36.86 
 
 
283 aa  176  5e-43  Campylobacter concisus 13826  Bacteria  normal  0.048214  n/a   
 
 
-
 
NC_005945  BAS4085  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  37.07 
 
 
286 aa  174  9.999999999999999e-43  Bacillus anthracis str. Sterne  Bacteria  hitchhiker  0.00334729  n/a   
 
 
-
 
NC_007530  GBAA_4405  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  37.07 
 
 
286 aa  174  9.999999999999999e-43  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  n/a   
 
 
-
 
NC_011059  Paes_1178  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  37.37 
 
 
295 aa  174  9.999999999999999e-43  Prosthecochloris aestuarii DSM 271  Bacteria  normal  normal  0.545639 
 
 
-
 
NC_009674  Bcer98_2874  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  36.52 
 
 
286 aa  174  9.999999999999999e-43  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  0.126852  n/a   
 
 
-
 
NC_010184  BcerKBAB4_4033  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  37.41 
 
 
286 aa  174  1.9999999999999998e-42  Bacillus weihenstephanensis KBAB4  Bacteria  normal  0.781388  n/a   
 
 
-
 
NC_007955  Mbur_1814  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  36.03 
 
 
286 aa  174  1.9999999999999998e-42  Methanococcoides burtonii DSM 6242  Archaea  normal  0.279285  n/a   
 
 
-
 
NC_011898  Ccel_0604  tetrahydrofolate dehydrogenase/cyclohydrolase  37.33 
 
 
284 aa  174  1.9999999999999998e-42  Clostridium cellulolyticum H10  Bacteria  normal  n/a   
 
 
-
 
NC_008639  Cpha266_0997  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  38.54 
 
 
308 aa  173  2.9999999999999996e-42  Chlorobium phaeobacteroides DSM 266  Bacteria  normal  n/a   
 
 
-
 
NC_013385  Adeg_1278  Methylenetetrahydrofolate dehydrogenase (NADP(+))  40.55 
 
 
282 aa  173  3.9999999999999995e-42  Ammonifex degensii KC4  Bacteria  normal  0.568567  n/a   
 
 
-
 
NC_010085  Nmar_1117  methylenetetrahydrofolate dehydrogenase  36.3 
 
 
287 aa  173  3.9999999999999995e-42  Nitrosopumilus maritimus SCM1  Archaea  n/a    normal  0.434415 
 
 
-
 
NC_005957  BT9727_3923  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  36.73 
 
 
286 aa  172  5e-42  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  n/a   
 
 
-
 
NC_006274  BCZK3934  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  36.73 
 
 
286 aa  172  5e-42  Bacillus cereus E33L  Bacteria  normal  0.0428362  n/a   
 
 
-
 
NC_011773  BCAH820_4201  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  36.73 
 
 
286 aa  172  5e-42  Bacillus cereus AH820  Bacteria  n/a    hitchhiker  3.73931e-16 
 
 
-
 
NC_012560  Avin_23540  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  39.85 
 
 
284 aa  172  5e-42  Azotobacter vinelandii DJ  Bacteria  normal  n/a   
 
 
-
 
NC_007355  Mbar_A2315  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  37.54 
 
 
287 aa  171  1e-41  Methanosarcina barkeri str. Fusaro  Archaea  normal  normal 
 
 
-
 
NC_011772  BCG9842_B0943  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  36.73 
 
 
286 aa  171  1e-41  Bacillus cereus G9842  Bacteria  normal  hitchhiker  0.00348961 
 
 
-
 
NC_011725  BCB4264_A4291  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  36.73 
 
 
286 aa  171  1e-41  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_008527  LACR_0921  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  38.01 
 
 
295 aa  171  1e-41  Lactococcus lactis subsp. cremoris SK11  Bacteria  unclonable  0.0000659615  n/a   
 
 
-
 
NC_011658  BCAH187_A4311  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  36.73 
 
 
286 aa  171  1e-41  Bacillus cereus AH187  Bacteria  normal  0.0277859  n/a   
 
 
-
 
NC_008599  CFF8240_1174  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  35.91 
 
 
283 aa  171  1e-41  Campylobacter fetus subsp. fetus 82-40  Bacteria  normal  0.840508  n/a   
 
 
-
 
NC_003909  BCE_4254  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  36.73 
 
 
286 aa  171  2e-41  Bacillus cereus ATCC 10987  Bacteria  normal  0.246013  n/a   
 
 
-
 
NC_011899  Hore_06480  tetrahydrofolate dehydrogenase/cyclohydrolase  36.52 
 
 
283 aa  171  2e-41  Halothermothrix orenii H 168  Bacteria  hitchhiker  0.000000303472  n/a   
 
 
-
 
NC_014165  Tbis_0661  methylenetetrahydrofolate dehydrogenase (NADP(+))  39.4 
 
 
284 aa  171  2e-41  Thermobispora bispora DSM 43833  Bacteria  normal  0.839068  normal  0.303542 
 
 
-
 
NC_009483  Gura_1169  methylenetetrahydrofolate dehydrogenase (NADP(+))  38.44 
 
 
280 aa  170  3e-41  Geobacter uraniireducens Rf4  Bacteria  hitchhiker  0.00000103166  n/a   
 
 
-
 
NC_007633  MCAP_0706  methylene-tetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase  35.96 
 
 
284 aa  169  4e-41  Mycoplasma capricolum subsp. capricolum ATCC 27343  Bacteria  normal  n/a   
 
 
-
 
NC_013595  Sros_1250  Methylenetetrahydrofolate dehydrogenase (NADP(+))  39.86 
 
 
282 aa  169  4e-41  Streptosporangium roseum DSM 43021  Bacteria  normal  normal  0.0286426 
 
 
-
 
NC_008576  Mmc1_3712  methenyltetrahydrofolate cyclohydrolase  38.28 
 
 
285 aa  169  4e-41  Magnetococcus sp. MC-1  Bacteria  normal  normal 
 
 
-
 
NC_008463  PA14_41350  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  39.18 
 
 
284 aa  169  7e-41  Pseudomonas aeruginosa UCBPP-PA14  Bacteria  normal  normal  0.471362 
 
 
-
 
NC_011884  Cyan7425_0973  Methylenetetrahydrofolate dehydrogenase (NADP(+))  39.25 
 
 
293 aa  168  9e-41  Cyanothece sp. PCC 7425  Bacteria  normal  0.150063  normal  0.215441 
 
 
-
 
NC_002967  TDE0013  methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase  38.03 
 
 
293 aa  168  1e-40  Treponema denticola ATCC 35405  Bacteria  normal  n/a   
 
 
-
 
NC_002976  SERP0648  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  34.59 
 
 
286 aa  167  1e-40  Staphylococcus epidermidis RP62A  Bacteria  normal  n/a   
 
 
-
 
NC_008340  Mlg_0591  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  35.37 
 
 
286 aa  167  1e-40  Alkalilimnicola ehrlichii MLHE-1  Bacteria  hitchhiker  0.0000074286  unclonable  2.0108800000000004e-18 
 
 
-
 
NC_010803  Clim_1112  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  40.07 
 
 
296 aa  168  1e-40  Chlorobium limicola DSM 245  Bacteria  normal  n/a   
 
 
-
 
NC_010655  Amuc_1641  Methenyltetrahydrofolate cyclohydrolase  35.45 
 
 
291 aa  168  1e-40  Akkermansia muciniphila ATCC BAA-835  Bacteria  normal  normal  0.794405 
 
 
-
 
NC_009656  PSPA7_3507  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  39.18 
 
 
284 aa  167  2e-40  Pseudomonas aeruginosa PA7  Bacteria  normal  n/a   
 
 
-
 
NC_007517  Gmet_1162  methenyltetrahydrofolate cyclohydrolase  36.52 
 
 
285 aa  167  2e-40  Geobacter metallireducens GS-15  Bacteria  hitchhiker  0.00000000377219  hitchhiker  0.00798692 
 
 
-
 
NC_009253  Dred_1073  methylenetetrahydrofolate dehydrogenase (NADP(+))  36.08 
 
 
284 aa  167  2e-40  Desulfotomaculum reducens MI-1  Bacteria  normal  0.174822  n/a   
 
 
-
 
NC_011060  Ppha_1205  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  38.77 
 
 
295 aa  167  2e-40  Pelodictyon phaeoclathratiforme BU-1  Bacteria  normal  n/a   
 
 
-
 
NC_008148  Rxyl_0827  methenyltetrahydrofolate cyclohydrolase  38.57 
 
 
284 aa  165  9e-40  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  0.997708  n/a   
 
 
-
 
NC_011726  PCC8801_1592  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  36.39 
 
 
292 aa  165  1.0000000000000001e-39  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_012918  GM21_2719  Methylenetetrahydrofolate dehydrogenase (NADP(+))  36.39 
 
 
281 aa  164  1.0000000000000001e-39  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_013501  Rmar_0952  Methenyltetrahydrofolate cyclohydrolase  40.81 
 
 
293 aa  165  1.0000000000000001e-39  Rhodothermus marinus DSM 4252  Bacteria  normal  n/a   
 
 
-
 
NC_007413  Ava_2703  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  36.27 
 
 
299 aa  164  2.0000000000000002e-39  Anabaena variabilis ATCC 29413  Bacteria  hitchhiker  0.00240961  normal  0.676317 
 
 
-
 
NC_008044  TM1040_2356  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  37.12 
 
 
300 aa  164  2.0000000000000002e-39  Ruegeria sp. TM1040  Bacteria  normal  normal  0.531119 
 
 
-
 
NC_013161  Cyan8802_1617  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  37.07 
 
 
292 aa  163  4.0000000000000004e-39  Cyanothece sp. PCC 8802  Bacteria  normal  normal 
 
 
-
 
NC_008789  Hhal_0610  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  38.04 
 
 
290 aa  163  4.0000000000000004e-39  Halorhodospira halophila SL1  Bacteria  normal  0.565768  n/a   
 
 
-
 
NC_008312  Tery_4172  methenyltetrahydrofolate cyclohydrolase  36.73 
 
 
287 aa  162  4.0000000000000004e-39  Trichodesmium erythraeum IMS101  Bacteria  normal  normal  0.280923 
 
 
-
 
NC_011146  Gbem_1497  tetrahydrofolate dehydrogenase/cyclohydrolase  35.71 
 
 
281 aa  162  4.0000000000000004e-39  Geobacter bemidjiensis Bem  Bacteria  hitchhiker  0.0000244416  n/a   
 
 
-
 
NC_011830  Dhaf_3496  Methylenetetrahydrofolate dehydrogenase (NADP(+))  33.9 
 
 
284 aa  162  5.0000000000000005e-39  Desulfitobacterium hafniense DCB-2  Bacteria  normal  n/a   
 
 
-
 
NC_011729  PCC7424_0607  Methenyltetrahydrofolate cyclohydrolase  36.52 
 
 
301 aa  162  9e-39  Cyanothece sp. PCC 7424  Bacteria  n/a    normal 
 
 
-
 
NC_004116  SAG0494  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  36.39 
 
 
284 aa  161  1e-38  Streptococcus agalactiae 2603V/R  Bacteria  normal  n/a   
 
 
-
 
NC_006055  Mfl167  methylenetetrahydrofolate dehydrogenase  35.52 
 
 
286 aa  161  1e-38  Mesoplasma florum L1  Bacteria  hitchhiker  0.00296067  n/a   
 
 
-
 
NC_010718  Nther_1700  5,10-methylenetetrahydrofolate dehydrogenase (NADP+), Methenyltetrahydrofolate cyclohydrolase  35.62 
 
 
284 aa  161  1e-38  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  normal  0.335496 
 
 
-
 
NC_008530  LGAS_0751  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  33.79 
 
 
282 aa  161  1e-38  Lactobacillus gasseri ATCC 33323  Bacteria  normal  0.0811051  hitchhiker  0.000994915 
 
 
-
 
NC_011832  Mpal_0744  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  35.15 
 
 
280 aa  160  2e-38  Methanosphaerula palustris E1-9c  Archaea  normal  normal 
 
 
-
 
NC_004578  PSPTO_3733  methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase  37.07 
 
 
284 aa  160  2e-38  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  0.0898876  n/a   
 
 
-
 
NC_009439  Pmen_2048  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  37.64 
 
 
284 aa  160  2e-38  Pseudomonas mendocina ymp  Bacteria  normal  0.629007  normal  0.184517 
 
 
-
 
NC_014148  Plim_3436  Methylenetetrahydrofolate dehydrogenase (NADP(+))  36.12 
 
 
291 aa  161  2e-38  Planctomyces limnophilus DSM 3776  Bacteria  normal  n/a   
 
 
-
 
NC_002939  GSU0862  folD bifunctional protein  38.1 
 
 
285 aa  160  3e-38  Geobacter sulfurreducens PCA  Bacteria  normal  n/a   
 
 
-
 
NC_007575  Suden_1113  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  34.58 
 
 
285 aa  160  3e-38  Sulfurimonas denitrificans DSM 1251  Bacteria  normal  0.947222  n/a   
 
 
-
 
NC_009512  Pput_3472  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  38.72 
 
 
299 aa  160  4e-38  Pseudomonas putida F1  Bacteria  normal  hitchhiker  0.000179618 
 
 
-
 
NC_010501  PputW619_1739  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  38.72 
 
 
284 aa  159  4e-38  Pseudomonas putida W619  Bacteria  normal  normal  0.168227 
 
 
-
 
NC_010322  PputGB1_1899  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  37.59 
 
 
290 aa  160  4e-38  Pseudomonas putida GB-1  Bacteria  normal  0.605339  normal  0.0542462 
 
 
-
 
NC_002947  PP_2265  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  37.59 
 
 
284 aa  159  5e-38  Pseudomonas putida KT2440  Bacteria  normal  0.382632  decreased coverage  0.000766726 
 
 
-
 
NC_010320  Teth514_1535  methenyltetrahydrofolate cyclohydrolase  32.3 
 
 
286 aa  159  5e-38  Thermoanaerobacter sp. X514  Bacteria  normal  0.0500443  n/a   
 
 
-
 
NC_007005  Psyr_1743  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  37.07 
 
 
284 aa  159  5e-38  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  0.83996  normal 
 
 
-
 
NC_014158  Tpau_0941  Methylenetetrahydrofolate dehydrogenase (NADP(+))  38.82 
 
 
294 aa  159  5e-38  Tsukamurella paurometabola DSM 20162  Bacteria  normal  n/a   
 
 
-
 
NC_013159  Svir_05000  methenyltetrahydrofolate cyclohydrolase /5,10-methylenetetrahydrofolate dehydrogenase (NADP+)  39.37 
 
 
284 aa  159  6e-38  Saccharomonospora viridis DSM 43017  Bacteria  normal  normal 
 
 
-
 
NC_011666  Msil_1881  Methenyltetrahydrofolate cyclohydrolase  36.4 
 
 
318 aa  159  8e-38  Methylocella silvestris BL2  Bacteria  n/a    normal 
 
 
-
 
NC_009712  Mboo_2188  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  36.73 
 
 
278 aa  158  8e-38  Candidatus Methanoregula boonei 6A8  Archaea  normal  0.590033  normal 
 
 
-
 
NC_010117  COXBURSA331_A0419  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  34.35 
 
 
283 aa  157  1e-37  Coxiella burnetii RSA 331  Bacteria  hitchhiker  0.0000000000859171  n/a   
 
 
-
 
NC_014248  Aazo_1506  methenyltetrahydrofolate cyclohydrolase  37.25 
 
 
294 aa  157  1e-37  'Nostoc azollae' 0708  Bacteria  normal  n/a   
 
 
-
 
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