More than 300 homologs were found in PanDaTox collection
for query gene Amir_4015 on replicon NC_013093
Organism: Actinosynnema mirum DSM 43827



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Replicon accession
Locus tag
Product
% identity
Alignment on query gene
Alignment on homolog gene
Length
Bit score

E-value
Organism name
Kingdom
Plasmid clonability
Plasmid unclonability p-value
Fosmid clonability
Fosmid unclonability p-value
Coverage Plot
PanDaTox homologs
Experimental validation
NC_013093  Amir_4015  Methylenetetrahydrofolate dehydrogenase (NADP(+))  100 
 
 		 285 aa  563  1e-160  Actinosynnema mirum DSM 43827  Bacteria  normal  0.305417  n/a   
 
 
-
 
NC_013131  Caci_8052  Methylenetetrahydrofolate dehydrogenase (NADP(+))  69.45 
 
 		 278 aa  360  2e-98  Catenulispora acidiphila DSM 44928  Bacteria  normal  1  normal  0.592231 
 
 
-
 
NC_009953  Sare_0067  methylenetetrahydrofolate dehydrogenase (NADP(+))  67.03 
 
 		 279 aa  352  2.9999999999999997e-96  Salinispora arenicola CNS-205  Bacteria  normal  0.582205  normal  1 
 
 
-
 
NC_013159  Svir_11680  methenyltetrahydrofolate cyclohydrolase /5,10-methylenetetrahydrofolate dehydrogenase (NADP+)  67.03 
 
 		 286 aa  335  3.9999999999999995e-91  Saccharomonospora viridis DSM 43017  Bacteria  normal  1  normal  1 
 
 
-
 
NC_014158  Tpau_1907  Methylenetetrahydrofolate dehydrogenase (NADP(+))  66.67 
 
 		 295 aa  331  8e-90  Tsukamurella paurometabola DSM 20162  Bacteria  normal  0.0709854  n/a   
 
 
-
 
NC_007912  Sde_1920  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  56.73 
 
 		 280 aa  324  1e-87  Saccharophagus degradans 2-40  Bacteria  hitchhiker  0.00000000163065  normal  1 
 
 
-
 
NC_007204  Psyc_0673  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  56.07 
 
 		 295 aa  315  4e-85  Psychrobacter arcticus 273-4  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009524  PsycPRwf_1815  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  54.9 
 
 		 291 aa  315  6e-85  Psychrobacter sp. PRwf-1  Bacteria  normal  1  normal  0.0140055 
 
 
-
 
NC_007969  Pcryo_0640  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  55.71 
 
 		 298 aa  312  3.9999999999999997e-84  Psychrobacter cryohalolentis K5  Bacteria  normal  0.314265  normal  1 
 
 
-
 
NC_009654  Mmwyl1_3759  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  53.99 
 
 		 280 aa  307  1.0000000000000001e-82  Marinomonas sp. MWYL1  Bacteria  normal  1  normal  0.585683 
 
 
-
 
NC_008576  Mmc1_3712  methenyltetrahydrofolate cyclohydrolase  52.33 
 
 		 285 aa  278  5e-74  Magnetococcus sp. MC-1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_007644  Moth_1516  methenyltetrahydrofolate cyclohydrolase  51.6 
 
 		 280 aa  276  3e-73  Moorella thermoacetica ATCC 39073  Bacteria  normal  1  normal  1 
 
 
-
 
NC_003910  CPS_3133  FolD bifunctional protein  53.85 
 
 		 282 aa  269  4e-71  Colwellia psychrerythraea 34H  Bacteria  normal  0.203744  n/a   
 
 
-
 
NC_008825  Mpe_A2131  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  50.9 
 
 		 283 aa  266  2.9999999999999995e-70  Methylibium petroleiphilum PM1  Bacteria  normal  0.386646  normal  1 
 
 
-
 
NC_010814  Glov_0508  Methenyltetrahydrofolate cyclohydrolase  52.31 
 
 		 284 aa  263  3e-69  Geobacter lovleyi SZ  Bacteria  decreased coverage  0.0000347177  n/a   
 
 
-
 
NC_007517  Gmet_1162  methenyltetrahydrofolate cyclohydrolase  48.91 
 
 		 285 aa  260  2e-68  Geobacter metallireducens GS-15  Bacteria  hitchhiker  0.00000000377219  hitchhiker  0.00798692 
 
 
-
 
NC_012918  GM21_2719  Methylenetetrahydrofolate dehydrogenase (NADP(+))  48.75 
 
 		 281 aa  259  5.0000000000000005e-68  Geobacter sp. M21  Bacteria  n/a    normal  1 
 
 
-
 
NC_011146  Gbem_1497  tetrahydrofolate dehydrogenase/cyclohydrolase  48.39 
 
 		 281 aa  258  8e-68  Geobacter bemidjiensis Bem  Bacteria  hitchhiker  0.0000244416  n/a   
 
 
-
 
NC_007794  Saro_3300  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  51.05 
 
 		 297 aa  258  8e-68  Novosphingobium aromaticivorans DSM 12444  Bacteria  normal  1  n/a   
 
 
-
 
NC_011206  Lferr_1552  Methylenetetrahydrofolate dehydrogenase (NADP(+))  51.26 
 
 		 288 aa  258  1e-67  Acidithiobacillus ferrooxidans ATCC 53993  Bacteria  normal  1  hitchhiker  0.0000645737 
 
 
-
 
NC_011761  AFE_1877  methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase  51.26 
 
 		 288 aa  258  1e-67  Acidithiobacillus ferrooxidans ATCC 23270  Bacteria  normal  0.337489  n/a   
 
 
-
 
NC_009483  Gura_1169  methylenetetrahydrofolate dehydrogenase (NADP(+))  47.86 
 
 		 280 aa  256  3e-67  Geobacter uraniireducens Rf4  Bacteria  hitchhiker  0.00000103166  n/a   
 
 
-
 
NC_010718  Nther_1700  5,10-methylenetetrahydrofolate dehydrogenase (NADP+), Methenyltetrahydrofolate cyclohydrolase  50.97 
 
 		 284 aa  255  7e-67  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  1  normal  0.335496 
 
 
-
 
NC_007947  Mfla_0073  methenyltetrahydrofolate cyclohydrolase  48.55 
 
 		 289 aa  254  1.0000000000000001e-66  Methylobacillus flagellatus KT  Bacteria  hitchhiker  0.0002304  normal  1 
 
 
-
 
NC_012560  Avin_23540  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  49.29 
 
 		 284 aa  253  2.0000000000000002e-66  Azotobacter vinelandii DJ  Bacteria  normal  1  n/a   
 
 
-
 
NC_008789  Hhal_0610  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  48.23 
 
 		 290 aa  252  4.0000000000000004e-66  Halorhodospira halophila SL1  Bacteria  normal  0.565768  n/a   
 
 
-
 
NC_011899  Hore_06480  tetrahydrofolate dehydrogenase/cyclohydrolase  47.52 
 
 		 283 aa  252  4.0000000000000004e-66  Halothermothrix orenii H 168  Bacteria  hitchhiker  0.000000303472  n/a   
 
 
-
 
NC_002939  GSU0862  folD bifunctional protein  50.72 
 
 		 285 aa  251  8.000000000000001e-66  Geobacter sulfurreducens PCA  Bacteria  normal  1  n/a   
 
 
-
 
NC_010524  Lcho_1643  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  49.82 
 
 		 287 aa  250  2e-65  Leptothrix cholodnii SP-6  Bacteria  n/a    normal  0.0588013 
 
 
-
 
NC_013173  Dbac_3223  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  47.83 
 
 		 281 aa  250  2e-65  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  1  n/a   
 
 
-
 
NC_009439  Pmen_2048  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  50.54 
 
 		 284 aa  250  2e-65  Pseudomonas mendocina ymp  Bacteria  normal  0.629007  normal  0.184517 
 
 
-
 
NC_008309  HS_1221  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  44.68 
 
 		 282 aa  249  2e-65  Haemophilus somnus 129PT  Bacteria  decreased coverage  0.00020406  n/a   
 
 
-
 
NC_008463  PA14_41350  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  50.54 
 
 		 284 aa  250  2e-65  Pseudomonas aeruginosa UCBPP-PA14  Bacteria  normal  1  normal  0.471362 
 
 
-
 
NC_009012  Cthe_1093  methenyltetrahydrofolate cyclohydrolase  43.62 
 
 		 285 aa  249  5e-65  Clostridium thermocellum ATCC 27405  Bacteria  hitchhiker  0.000000512009  n/a   
 
 
-
 
NC_002947  PP_2265  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  49.82 
 
 		 284 aa  247  1e-64  Pseudomonas putida KT2440  Bacteria  normal  0.382632  decreased coverage  0.000766726 
 
 
-
 
NC_009512  Pput_3472  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  49.82 
 
 		 299 aa  248  1e-64  Pseudomonas putida F1  Bacteria  normal  1  hitchhiker  0.000179618 
 
 
-
 
NC_010322  PputGB1_1899  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  49.82 
 
 		 290 aa  247  1e-64  Pseudomonas putida GB-1  Bacteria  normal  0.605339  normal  0.0542462 
 
 
-
 
NC_010506  Swoo_3115  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  48.21 
 
 		 286 aa  247  1e-64  Shewanella woodyi ATCC 51908  Bacteria  hitchhiker  0.00000143268  decreased coverage  0.000000300932 
 
 
-
 
NC_011901  Tgr7_0937  Methylenetetrahydrofolate dehydrogenase (NADP(+))  50.72 
 
 		 285 aa  247  1e-64  Thioalkalivibrio sp. HL-EbGR7  Bacteria  normal  0.693292  n/a   
 
 
-
 
NC_007948  Bpro_2675  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  50.6 
 
 		 281 aa  248  1e-64  Polaromonas sp. JS666  Bacteria  normal  1  normal  1 
 
 
-
 
NC_004578  PSPTO_3733  methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase  50.54 
 
 		 284 aa  247  2e-64  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  0.0898876  n/a   
 
 
-
 
NC_009656  PSPA7_3507  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  50.54 
 
 		 284 aa  246  2e-64  Pseudomonas aeruginosa PA7  Bacteria  normal  1  n/a   
 
 
-
 
NC_007298  Daro_0448  methenyltetrahydrofolate cyclohydrolase  46.98 
 
 		 284 aa  246  2e-64  Dechloromonas aromatica RCB  Bacteria  normal  0.326868  normal  0.769812 
 
 
-
 
NC_009092  Shew_2510  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  47.86 
 
 		 284 aa  247  2e-64  Shewanella loihica PV-4  Bacteria  hitchhiker  0.00000100149  normal  1 
 
 
-
 
NC_009675  Anae109_2520  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  52.14 
 
 		 281 aa  246  3e-64  Anaeromyxobacter sp. Fw109-5  Bacteria  normal  0.412381  normal  0.0135619 
 
 
-
 
NC_008752  Aave_2459  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  47.69 
 
 		 283 aa  246  4e-64  Acidovorax citrulli AAC00-1  Bacteria  normal  0.0798593  normal  1 
 
 
-
 
NC_009511  Swit_2872  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  50 
 
 		 304 aa  246  4e-64  Sphingomonas wittichii RW1  Bacteria  normal  1  normal  0.0451182 
 
 
-
 
NC_008781  Pnap_1778  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  46.95 
 
 		 281 aa  246  4e-64  Polaromonas naphthalenivorans CJ2  Bacteria  normal  1  normal  0.0122285 
 
 
-
 
NC_007005  Psyr_1743  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  50.18 
 
 		 284 aa  245  6e-64  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  0.83996  normal  1 
 
 
-
 
NC_010501  PputW619_1739  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  49.82 
 
 		 284 aa  245  6e-64  Pseudomonas putida W619  Bacteria  normal  1  normal  0.168227 
 
 
-
 
NC_008609  Ppro_0480  methenyltetrahydrofolate cyclohydrolase  49.1 
 
 		 283 aa  244  9e-64  Pelobacter propionicus DSM 2379  Bacteria  hitchhiker  0.00000146162  n/a   
 
 
-
 
NC_009783  VIBHAR_01391  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  48.75 
 
 		 286 aa  244  9e-64  Vibrio harveyi ATCC BAA-1116  Bacteria  n/a    n/a   
 
 
-
 
NC_009952  Dshi_1285  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  49.47 
 
 		 299 aa  244  9.999999999999999e-64  Dinoroseobacter shibae DFL 12  Bacteria  normal  0.0250299  normal  0.367155 
 
 
-
 
NC_011145  AnaeK_2618  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  56.4 
 
 		 282 aa  244  9.999999999999999e-64  Anaeromyxobacter sp. K  Bacteria  normal  0.442042  n/a   
 
 
-
 
NC_004347  SO_1792  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  47.5 
 
 		 284 aa  244  1.9999999999999999e-63  Shewanella oneidensis MR-1  Bacteria  n/a    n/a   
 
 
-
 
NC_008340  Mlg_0591  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  47.54 
 
 		 286 aa  243  1.9999999999999999e-63  Alkalilimnicola ehrlichii MLHE-1  Bacteria  hitchhiker  0.0000074286  unclonable  2.0108800000000004e-18 
 
 
-
 
NC_013456  VEA_004081  methylenetetrahydrofolate dehydrogenase (NADP+)/methenyltetrahydrofolate cyclohydrolase  47.67 
 
 		 286 aa  243  3e-63  Vibrio sp. Ex25  Bacteria  normal  0.897306  n/a   
 
 
-
 
NC_007347  Reut_A1299  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  49.11 
 
 		 283 aa  243  3e-63  Ralstonia eutropha JMP134  Bacteria  normal  0.293991  n/a   
 
 
-
 
NC_013501  Rmar_0952  Methenyltetrahydrofolate cyclohydrolase  47.26 
 
 		 293 aa  243  3e-63  Rhodothermus marinus DSM 4252  Bacteria  normal  1  n/a   
 
 
-
 
NC_013739  Cwoe_3588  Methylenetetrahydrofolate dehydrogenase (NADP(+))  50.9 
 
 		 283 aa  243  3e-63  Conexibacter woesei DSM 14684  Bacteria  normal  0.24704  normal  0.653023 
 
 
-
 
NC_009831  Ssed_1539  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  47.14 
 
 		 284 aa  243  3e-63  Shewanella sediminis HAW-EB3  Bacteria  hitchhiker  0.00454653  hitchhiker  0.000334608 
 
 
-
 
NC_011891  A2cp1_2712  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  55.6 
 
 		 282 aa  242  3.9999999999999997e-63  Anaeromyxobacter dehalogenans 2CP-1  Bacteria  normal  1  n/a   
 
 
-
 
NC_003910  CPS_3791  FolD bifunctional protein  45.04 
 
 		 284 aa  242  5e-63  Colwellia psychrerythraea 34H  Bacteria  normal  0.0390017  n/a   
 
 
-
 
NC_008700  Sama_1222  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  47.5 
 
 		 284 aa  242  5e-63  Shewanella amazonensis SB2B  Bacteria  hitchhiker  0.0000458246  normal  1 
 
 
-
 
NC_010424  Daud_0103  methenyltetrahydrofolate cyclohydrolase  48.74 
 
 		 294 aa  241  7e-63  Candidatus Desulforudis audaxviator MP104C  Bacteria  normal  1  n/a   
 
 
-
 
NC_007760  Adeh_1247  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  55.6 
 
 		 282 aa  241  7.999999999999999e-63  Anaeromyxobacter dehalogenans 2CP-C  Bacteria  normal  1  n/a   
 
 
-
 
NC_009438  Sputcn32_1488  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  46.79 
 
 		 284 aa  241  1e-62  Shewanella putrefaciens CN-32  Bacteria  hitchhiker  0.000000791428  n/a   
 
 
-
 
NC_009802  CCC13826_0832  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  46.57 
 
 		 283 aa  241  1e-62  Campylobacter concisus 13826  Bacteria  normal  0.048214  n/a   
 
 
-
 
NC_011726  PCC8801_1592  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  46.76 
 
 		 292 aa  241  1e-62  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_008322  Shewmr7_2565  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  47.5 
 
 		 284 aa  241  1e-62  Shewanella sp. MR-7  Bacteria  unclonable  0.00000214044  normal  0.0576142 
 
 
-
 
NC_013421  Pecwa_1347  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  46.07 
 
 		 287 aa  240  2e-62  Pectobacterium wasabiae WPP163  Bacteria  normal  0.921359  n/a   
 
 
-
 
NC_007492  Pfl01_3699  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  49.1 
 
 		 284 aa  240  2e-62  Pseudomonas fluorescens Pf0-1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_010002  Daci_3983  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  47.52 
 
 		 284 aa  240  2e-62  Delftia acidovorans SPH-1  Bacteria  normal  0.763661  normal  0.0287042 
 
 
-
 
NC_014148  Plim_3436  Methylenetetrahydrofolate dehydrogenase (NADP(+))  44.6 
 
 		 291 aa  240  2e-62  Planctomyces limnophilus DSM 3776  Bacteria  normal  1  n/a   
 
 
-
 
NC_013161  Cyan8802_1617  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  46.1 
 
 		 292 aa  240  2e-62  Cyanothece sp. PCC 8802  Bacteria  normal  1  normal  1 
 
 
-
 
NC_012917  PC1_2931  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  45.71 
 
 		 287 aa  240  2e-62  Pectobacterium carotovorum subsp. carotovorum PC1  Bacteria  normal  0.775448  n/a   
 
 
-
 
NC_008062  Bcen_5937  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  48.61 
 
 		 285 aa  240  2e-62  Burkholderia cenocepacia AU 1054  Bacteria  normal  0.282272  n/a   
 
 
-
 
NC_008321  Shewmr4_2497  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  47.5 
 
 		 284 aa  240  2e-62  Shewanella sp. MR-4  Bacteria  decreased coverage  0.000000101338  normal  0.0187987 
 
 
-
 
NC_008577  Shewana3_2663  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  47.5 
 
 		 284 aa  240  2e-62  Shewanella sp. ANA-3  Bacteria  hitchhiker  0.00000544114  normal  0.482373 
 
 
-
 
NC_013440  Hoch_3221  Methylenetetrahydrofolate dehydrogenase (NADP(+))  47.18 
 
 		 287 aa  239  2.9999999999999997e-62  Haliangium ochraceum DSM 14365  Bacteria  normal  0.690635  normal  0.130494 
 
 
-
 
NC_010084  Bmul_1130  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  48.21 
 
 		 285 aa  239  2.9999999999999997e-62  Burkholderia multivorans ATCC 17616  Bacteria  normal  1  normal  0.675331 
 
 
-
 
NC_007604  Synpcc7942_0777  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  48.58 
 
 		 289 aa  239  2.9999999999999997e-62  Synechococcus elongatus PCC 7942  Bacteria  normal  0.71594  normal  0.0994354 
 
 
-
 
NC_008740  Maqu_1842  methylenetetrahydrofolate dehydrogenase (NADP(+))  48.39 
 
 		 304 aa  239  2.9999999999999997e-62  Marinobacter aquaeolei VT8  Bacteria  normal  0.0144811  n/a   
 
 
-
 
NC_012912  Dd1591_1250  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  46.79 
 
 		 289 aa  239  2.9999999999999997e-62  Dickeya zeae Ech1591  Bacteria  normal  0.0185449  n/a   
 
 
-
 
NC_008345  Sfri_2598  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  45.71 
 
 		 284 aa  239  2.9999999999999997e-62  Shewanella frigidimarina NCIMB 400  Bacteria  hitchhiker  0.00000158898  n/a   
 
 
-
 
NC_008782  Ajs_2128  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  47.16 
 
 		 282 aa  239  2.9999999999999997e-62  Acidovorax sp. JS42  Bacteria  normal  1  normal  0.616371 
 
 
-
 
NC_009901  Spea_2683  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  47.14 
 
 		 284 aa  239  4e-62  Shewanella pealeana ATCC 700345  Bacteria  hitchhiker  0.000000347397  n/a   
 
 
-
 
NC_011992  Dtpsy_1654  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  46.81 
 
 		 282 aa  239  5e-62  Acidovorax ebreus TPSY  Bacteria  normal  1  n/a   
 
 
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NC_009997  Sbal195_1625  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  47.14 
 
 		 284 aa  239  5e-62  Shewanella baltica OS195  Bacteria  unclonable  0.000000188982  normal  1 
 
 
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NC_011662  Tmz1t_3190  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  47.72 
 
 		 295 aa  238  5.999999999999999e-62  Thauera sp. MZ1T  Bacteria  normal  0.905813  n/a   
 
 
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NC_007802  Jann_0983  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  48.77 
 
 		 308 aa  238  5.999999999999999e-62  Jannaschia sp. CCS1  Bacteria  normal  0.170937  normal  1 
 
 
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NC_011884  Cyan7425_0973  Methylenetetrahydrofolate dehydrogenase (NADP(+))  45.55 
 
 		 293 aa  238  5.999999999999999e-62  Cyanothece sp. PCC 7425  Bacteria  normal  0.150063  normal  0.215441 
 
 
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NC_008542  Bcen2424_2140  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  48.61 
 
 		 285 aa  238  6.999999999999999e-62  Burkholderia cenocepacia HI2424  Bacteria  normal  0.812811  n/a   
 
 
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NC_010508  Bcenmc03_2158  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  48.61 
 
 		 286 aa  238  8e-62  Burkholderia cenocepacia MC0-3  Bacteria  normal  1  normal  1 
 
 
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NC_009052  Sbal_1602  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  47.14 
 
 		 284 aa  238  1e-61  Shewanella baltica OS155  Bacteria  unclonable  0.00000000125138  n/a   
 
 
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NC_009665  Shew185_1591  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  47.14 
 
 		 284 aa  238  1e-61  Shewanella baltica OS185  Bacteria  unclonable  0.0000000000513684  n/a   
 
 
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NC_011663  Sbal223_2752  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  47.14 
 
 		 284 aa  238  1e-61  Shewanella baltica OS223  Bacteria  unclonable  0.00000000267118  normal  0.0701472 
 
 
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NC_008686  Pden_2614  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  49.29 
 
 		 298 aa  238  1e-61  Paracoccus denitrificans PD1222  Bacteria  normal  0.508138  normal  1 
 
 
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NC_007963  Csal_2048  methenyltetrahydrofolate cyclohydrolase  47.5 
 
 		 287 aa  238  1e-61  Chromohalobacter salexigens DSM 3043  Bacteria  decreased coverage  0.0000169412  n/a   
 
 
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NC_010338  Caul_1714  bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase  47.59 
 
 		 298 aa  238  1e-61  Caulobacter sp. K31  Bacteria  normal  0.0298416  normal  0.218409 
 
 
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