More than 300 homologs were found in PanDaTox collection
for query gene Cagg_3190 on replicon NC_011831
Organism: Chloroflexus aggregans DSM 9485



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_011831  Cagg_3190  glucose-6-phosphate 1-dehydrogenase  100 
 
 
513 aa  1055    Chloroflexus aggregans DSM 9485  Bacteria  normal  normal  0.767054 
 
 
-
 
NC_013525  Tter_0413  glucose-6-phosphate 1-dehydrogenase  60.89 
 
 
514 aa  643    Thermobaculum terrenum ATCC BAA-798  Bacteria  n/a    n/a   
 
 
-
 
NC_009767  Rcas_1852  glucose-6-phosphate 1-dehydrogenase  68.18 
 
 
518 aa  709    Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.214037  normal  0.860492 
 
 
-
 
NC_009523  RoseRS_2562  glucose-6-phosphate 1-dehydrogenase  67.38 
 
 
513 aa  692    Roseiflexus sp. RS-1  Bacteria  normal  normal 
 
 
-
 
NC_009972  Haur_3021  glucose-6-phosphate 1-dehydrogenase  60.55 
 
 
508 aa  631  1e-180  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  0.0908495  n/a   
 
 
-
 
NC_011726  PCC8801_3806  glucose-6-phosphate 1-dehydrogenase  59.37 
 
 
509 aa  611  9.999999999999999e-175  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_013161  Cyan8802_3858  glucose-6-phosphate 1-dehydrogenase  59.37 
 
 
509 aa  611  9.999999999999999e-175  Cyanothece sp. PCC 8802  Bacteria  normal  normal 
 
 
-
 
NC_011884  Cyan7425_3427  glucose-6-phosphate 1-dehydrogenase  59.49 
 
 
509 aa  613  9.999999999999999e-175  Cyanothece sp. PCC 7425  Bacteria  normal  0.349036  normal  0.556859 
 
 
-
 
NC_011729  PCC7424_1498  glucose-6-phosphate 1-dehydrogenase  57.71 
 
 
509 aa  596  1e-169  Cyanothece sp. PCC 7424  Bacteria  n/a    hitchhiker  0.0000000000000268393 
 
 
-
 
NC_007604  Synpcc7942_2334  glucose-6-phosphate 1-dehydrogenase  56.42 
 
 
511 aa  586  1e-166  Synechococcus elongatus PCC 7942  Bacteria  normal  normal 
 
 
-
 
NC_008312  Tery_0684  glucose-6-phosphate 1-dehydrogenase  57.51 
 
 
509 aa  584  1.0000000000000001e-165  Trichodesmium erythraeum IMS101  Bacteria  normal  normal  0.10488 
 
 
-
 
NC_014248  Aazo_1091  glucose-6-phosphate 1-dehydrogenase  56.05 
 
 
509 aa  572  1.0000000000000001e-162  'Nostoc azollae' 0708  Bacteria  normal  n/a   
 
 
-
 
NC_007413  Ava_1682  glucose-6-phosphate 1-dehydrogenase  55.77 
 
 
509 aa  570  1e-161  Anabaena variabilis ATCC 29413  Bacteria  normal  normal 
 
 
-
 
NC_008148  Rxyl_0051  glucose-6-phosphate 1-dehydrogenase  57.83 
 
 
510 aa  570  1e-161  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  n/a   
 
 
-
 
NC_010571  Oter_3908  glucose-6-phosphate 1-dehydrogenase  53.62 
 
 
512 aa  543  1e-153  Opitutus terrae PB90-1  Bacteria  normal  0.313337  normal  0.337503 
 
 
-
 
NC_007760  Adeh_1439  glucose-6-phosphate 1-dehydrogenase  54.27 
 
 
503 aa  539  9.999999999999999e-153  Anaeromyxobacter dehalogenans 2CP-C  Bacteria  normal  0.074785  n/a   
 
 
-
 
NC_011145  AnaeK_2421  glucose-6-phosphate 1-dehydrogenase  54.27 
 
 
503 aa  541  9.999999999999999e-153  Anaeromyxobacter sp. K  Bacteria  normal  n/a   
 
 
-
 
NC_013595  Sros_6016  Glucose-6-phosphate dehydrogenase  55.03 
 
 
545 aa  541  9.999999999999999e-153  Streptosporangium roseum DSM 43021  Bacteria  normal  normal  0.558765 
 
 
-
 
NC_002620  TC0457  glucose-6-phosphate 1-dehydrogenase  53.36 
 
 
507 aa  535  1e-151  Chlamydia muridarum Nigg  Bacteria  unclonable  0.00414605  n/a   
 
 
-
 
NC_011891  A2cp1_2508  glucose-6-phosphate 1-dehydrogenase  53.66 
 
 
501 aa  537  1e-151  Anaeromyxobacter dehalogenans 2CP-1  Bacteria  normal  n/a   
 
 
-
 
NC_008025  Dgeo_1974  glucose-6-phosphate 1-dehydrogenase  53.71 
 
 
560 aa  538  1e-151  Deinococcus geothermalis DSM 11300  Bacteria  normal  normal  0.588725 
 
 
-
 
NC_008578  Acel_1124  glucose-6-phosphate 1-dehydrogenase  54.51 
 
 
508 aa  536  1e-151  Acidothermus cellulolyticus 11B  Bacteria  normal  decreased coverage  0.00734175 
 
 
-
 
NC_013510  Tcur_2210  glucose-6-phosphate 1-dehydrogenase  53.94 
 
 
507 aa  532  1e-150  Thermomonospora curvata DSM 43183  Bacteria  hitchhiker  0.00000230024  n/a   
 
 
-
 
NC_013530  Xcel_1555  glucose-6-phosphate 1-dehydrogenase  53.24 
 
 
514 aa  534  1e-150  Xylanimonas cellulosilytica DSM 15894  Bacteria  normal  n/a   
 
 
-
 
NC_013721  HMPREF0424_0185  glucose-6-phosphate dehydrogenase  51.47 
 
 
526 aa  531  1e-149  Gardnerella vaginalis 409-05  Bacteria  n/a    normal 
 
 
-
 
NC_007517  Gmet_2619  glucose-6-phosphate 1-dehydrogenase  54.1 
 
 
512 aa  529  1e-149  Geobacter metallireducens GS-15  Bacteria  normal  0.930273  normal 
 
 
-
 
NC_013521  Sked_19960  glucose-6-phosphate 1-dehydrogenase  52.75 
 
 
513 aa  527  1e-148  Sanguibacter keddieii DSM 10542  Bacteria  normal  0.401043  normal 
 
 
-
 
NC_009953  Sare_3319  glucose-6-phosphate 1-dehydrogenase  53.16 
 
 
505 aa  527  1e-148  Salinispora arenicola CNS-205  Bacteria  normal  hitchhiker  0.00190936 
 
 
-
 
NC_013093  Amir_5189  glucose-6-phosphate 1-dehydrogenase  52.13 
 
 
513 aa  523  1e-147  Actinosynnema mirum DSM 43827  Bacteria  normal  0.663685  n/a   
 
 
-
 
NC_013131  Caci_2244  glucose-6-phosphate 1-dehydrogenase  53.16 
 
 
540 aa  523  1e-147  Catenulispora acidiphila DSM 44928  Bacteria  normal  hitchhiker  0.0000605955 
 
 
-
 
NC_014210  Ndas_2976  glucose-6-phosphate 1-dehydrogenase  52.82 
 
 
517 aa  524  1e-147  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  0.925027  normal 
 
 
-
 
NC_014151  Cfla_1936  glucose-6-phosphate 1-dehydrogenase  51.65 
 
 
513 aa  522  1e-147  Cellulomonas flavigena DSM 20109  Bacteria  normal  0.0192784  normal 
 
 
-
 
NC_008726  Mvan_2718  glucose-6-phosphate 1-dehydrogenase  52.66 
 
 
509 aa  523  1e-147  Mycobacterium vanbaalenii PYR-1  Bacteria  normal  0.838131  normal  0.152629 
 
 
-
 
NC_009675  Anae109_3326  glucose-6-phosphate 1-dehydrogenase  54.38 
 
 
505 aa  522  1e-147  Anaeromyxobacter sp. Fw109-5  Bacteria  normal  0.0774281  normal 
 
 
-
 
NC_011886  Achl_1835  glucose-6-phosphate 1-dehydrogenase  52.27 
 
 
523 aa  519  1e-146  Arthrobacter chlorophenolicus A6  Bacteria  n/a    hitchhiker  0.000000247882 
 
 
-
 
NC_012669  Bcav_2163  glucose-6-phosphate 1-dehydrogenase  52.35 
 
 
508 aa  519  1e-146  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.153713  normal 
 
 
-
 
NC_014158  Tpau_2524  glucose-6-phosphate 1-dehydrogenase  54.03 
 
 
512 aa  521  1e-146  Tsukamurella paurometabola DSM 20162  Bacteria  normal  n/a   
 
 
-
 
NC_013441  Gbro_2372  glucose-6-phosphate 1-dehydrogenase  52.07 
 
 
512 aa  521  1e-146  Gordonia bronchialis DSM 43247  Bacteria  normal  0.340366  n/a   
 
 
-
 
NC_009077  Mjls_2452  glucose-6-phosphate 1-dehydrogenase  53.35 
 
 
523 aa  521  1e-146  Mycobacterium sp. JLS  Bacteria  decreased coverage  0.00235023  normal 
 
 
-
 
NC_008009  Acid345_2812  glucose-6-phosphate 1-dehydrogenase  51.56 
 
 
514 aa  520  1e-146  Candidatus Koribacter versatilis Ellin345  Bacteria  normal  normal 
 
 
-
 
NC_008146  Mmcs_2412  glucose-6-phosphate 1-dehydrogenase  53.35 
 
 
523 aa  521  1e-146  Mycobacterium sp. MCS  Bacteria  normal  n/a   
 
 
-
 
NC_008705  Mkms_2458  glucose-6-phosphate 1-dehydrogenase  53.35 
 
 
523 aa  521  1e-146  Mycobacterium sp. KMS  Bacteria  normal  0.230445  normal 
 
 
-
 
NC_010816  BLD_1241  glucose-6-phosphate 1-dehydrogenase  52.37 
 
 
515 aa  520  1e-146  Bifidobacterium longum DJO10A  Bacteria  normal  n/a   
 
 
-
 
NC_007333  Tfu_2005  glucose-6-phosphate 1-dehydrogenase  52.05 
 
 
534 aa  516  1.0000000000000001e-145  Thermobifida fusca YX  Bacteria  normal  n/a   
 
 
-
 
NC_013174  Jden_1262  glucose-6-phosphate 1-dehydrogenase  51.85 
 
 
513 aa  517  1.0000000000000001e-145  Jonesia denitrificans DSM 20603  Bacteria  normal  normal 
 
 
-
 
NC_008819  NATL1_15091  glucose-6-phosphate 1-dehydrogenase  51.98 
 
 
507 aa  515  1.0000000000000001e-145  Prochlorococcus marinus str. NATL1A  Bacteria  normal  normal 
 
 
-
 
NC_008541  Arth_2094  glucose-6-phosphate 1-dehydrogenase  52.07 
 
 
520 aa  515  1.0000000000000001e-145  Arthrobacter sp. FB24  Bacteria  normal  0.175031  n/a   
 
 
-
 
NC_008609  Ppro_2250  glucose-6-phosphate 1-dehydrogenase  51.83 
 
 
502 aa  517  1.0000000000000001e-145  Pelobacter propionicus DSM 2379  Bacteria  hitchhiker  0.000181168  n/a   
 
 
-
 
NC_008699  Noca_2538  glucose-6-phosphate 1-dehydrogenase  52.54 
 
 
516 aa  517  1.0000000000000001e-145  Nocardioides sp. JS614  Bacteria  normal  n/a   
 
 
-
 
NC_009664  Krad_2924  glucose-6-phosphate 1-dehydrogenase  52.86 
 
 
513 aa  515  1.0000000000000001e-145  Kineococcus radiotolerans SRS30216  Bacteria  normal  0.559692  normal 
 
 
-
 
NC_014165  Tbis_1983  glucose-6-phosphate 1-dehydrogenase  52.91 
 
 
529 aa  514  1e-144  Thermobispora bispora DSM 43833  Bacteria  normal  0.1665  normal  0.69024 
 
 
-
 
NC_007335  PMN2A_0676  glucose-6-phosphate 1-dehydrogenase  51.79 
 
 
507 aa  514  1e-144  Prochlorococcus marinus str. NATL2A  Bacteria  normal  n/a   
 
 
-
 
NC_009338  Mflv_3694  glucose-6-phosphate 1-dehydrogenase  51.17 
 
 
513 aa  514  1e-144  Mycobacterium gilvum PYR-GCK  Bacteria  normal  normal 
 
 
-
 
NC_012803  Mlut_11400  glucose-6-phosphate 1-dehydrogenase  52.23 
 
 
520 aa  510  1e-143  Micrococcus luteus NCTC 2665  Bacteria  normal  0.178593  n/a   
 
 
-
 
NC_009091  P9301_11811  glucose-6-phosphate 1-dehydrogenase  50 
 
 
507 aa  510  1e-143  Prochlorococcus marinus str. MIT 9301  Bacteria  normal  n/a   
 
 
-
 
NC_009976  P9211_11141  glucose-6-phosphate 1-dehydrogenase  51.19 
 
 
507 aa  510  1e-143  Prochlorococcus marinus str. MIT 9211  Bacteria  normal  normal 
 
 
-
 
NC_013159  Svir_15950  glucose-6-phosphate 1-dehydrogenase  52.37 
 
 
509 aa  508  1e-143  Saccharomonospora viridis DSM 43017  Bacteria  normal  0.0643236  normal  0.567165 
 
 
-
 
NC_008820  P9303_09401  glucose-6-phosphate 1-dehydrogenase  51.79 
 
 
507 aa  508  9.999999999999999e-143  Prochlorococcus marinus str. MIT 9303  Bacteria  n/a    normal  0.100308 
 
 
-
 
NC_013235  Namu_2260  glucose-6-phosphate 1-dehydrogenase  52.03 
 
 
516 aa  506  9.999999999999999e-143  Nakamurella multipartita DSM 44233  Bacteria  hitchhiker  0.000083899  normal  0.182304 
 
 
-
 
NC_009565  TBFG_11475  glucose-6-phosphate 1-dehydrogenase  51.77 
 
 
514 aa  506  9.999999999999999e-143  Mycobacterium tuberculosis F11  Bacteria  normal  0.0642944  normal  0.747487 
 
 
-
 
NC_008816  A9601_11801  glucose-6-phosphate 1-dehydrogenase  50.59 
 
 
507 aa  507  9.999999999999999e-143  Prochlorococcus marinus str. AS9601  Bacteria  normal  n/a   
 
 
-
 
NC_009380  Strop_3092  glucose-6-phosphate 1-dehydrogenase  51.58 
 
 
505 aa  504  1e-141  Salinispora tropica CNB-440  Bacteria  normal  normal  0.325189 
 
 
-
 
NC_007577  PMT9312_1085  glucose-6-phosphate 1-dehydrogenase  49.8 
 
 
507 aa  504  1e-141  Prochlorococcus marinus str. MIT 9312  Bacteria  normal  0.620961  n/a   
 
 
-
 
NC_014148  Plim_1200  glucose-6-phosphate 1-dehydrogenase  51.79 
 
 
522 aa  503  1e-141  Planctomyces limnophilus DSM 3776  Bacteria  normal  n/a   
 
 
-
 
NC_011899  Hore_16270  glucose-6-phosphate 1-dehydrogenase  49.39 
 
 
498 aa  502  1e-141  Halothermothrix orenii H 168  Bacteria  normal  n/a   
 
 
-
 
NC_013730  Slin_2700  glucose-6-phosphate 1-dehydrogenase  52.15 
 
 
499 aa  503  1e-141  Spirosoma linguale DSM 74  Bacteria  normal  0.130161  normal  0.149418 
 
 
-
 
NC_008817  P9515_11641  glucose-6-phosphate 1-dehydrogenase  49.6 
 
 
507 aa  502  1e-141  Prochlorococcus marinus str. MIT 9515  Bacteria  normal  0.789994  n/a   
 
 
-
 
NC_013172  Bfae_15250  glucose-6-phosphate 1-dehydrogenase  51.58 
 
 
517 aa  500  1e-140  Brachybacterium faecium DSM 4810  Bacteria  normal  0.10089  n/a   
 
 
-
 
NC_013947  Snas_2419  glucose-6-phosphate 1-dehydrogenase  49.61 
 
 
511 aa  500  1e-140  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  normal  0.421958 
 
 
-
 
NC_007516  Syncc9605_1918  glucose-6-phosphate 1-dehydrogenase  52.38 
 
 
507 aa  500  1e-140  Synechococcus sp. CC9605  Bacteria  normal  0.691213  normal 
 
 
-
 
NC_007519  Dde_3471  glucose-6-phosphate 1-dehydrogenase  50.5 
 
 
513 aa  501  1e-140  Desulfovibrio desulfuricans subsp. desulfuricans str. G20  Bacteria  normal  n/a   
 
 
-
 
NC_007644  Moth_2302  glucose-6-phosphate 1-dehydrogenase  51.55 
 
 
504 aa  498  1e-140  Moorella thermoacetica ATCC 39073  Bacteria  decreased coverage  0.00258738  normal 
 
 
-
 
NC_013757  Gobs_2055  glucose-6-phosphate 1-dehydrogenase  51.42 
 
 
505 aa  501  1e-140  Geodermatophilus obscurus DSM 43160  Bacteria  normal  n/a   
 
 
-
 
NC_010003  Pmob_1133  glucose-6-phosphate 1-dehydrogenase  49.39 
 
 
520 aa  496  1e-139  Petrotoga mobilis SJ95  Bacteria  normal  n/a   
 
 
-
 
NC_013169  Ksed_13180  glucose-6-phosphate 1-dehydrogenase  52.26 
 
 
515 aa  496  1e-139  Kytococcus sedentarius DSM 20547  Bacteria  normal  0.12336  normal 
 
 
-
 
NC_010320  Teth514_1417  glucose-6-phosphate 1-dehydrogenase  50.21 
 
 
485 aa  497  1e-139  Thermoanaerobacter sp. X514  Bacteria  normal  0.588108  n/a   
 
 
-
 
NC_009921  Franean1_2073  glucose-6-phosphate 1-dehydrogenase  51.22 
 
 
510 aa  498  1e-139  Frankia sp. EAN1pec  Bacteria  normal  0.398009  normal  0.0869756 
 
 
-
 
NC_007777  Francci3_1647  glucose-6-phosphate 1-dehydrogenase  51.33 
 
 
510 aa  497  1e-139  Frankia sp. CcI3  Bacteria  normal  0.336303  normal 
 
 
-
 
NC_007484  Noc_2062  glucose-6-phosphate 1-dehydrogenase  50.2 
 
 
507 aa  492  9.999999999999999e-139  Nitrosococcus oceani ATCC 19707  Bacteria  normal  0.155375  n/a   
 
 
-
 
NC_007513  Syncc9902_0748  glucose-6-phosphate 1-dehydrogenase  52.37 
 
 
507 aa  492  9.999999999999999e-139  Synechococcus sp. CC9902  Bacteria  normal  0.619417  n/a   
 
 
-
 
NC_007958  RPD_3476  glucose-6-phosphate 1-dehydrogenase  50.91 
 
 
503 aa  492  9.999999999999999e-139  Rhodopseudomonas palustris BisB5  Bacteria  normal  normal  0.320789 
 
 
-
 
NC_011004  Rpal_4157  glucose-6-phosphate 1-dehydrogenase  49.61 
 
 
504 aa  490  1e-137  Rhodopseudomonas palustris TIE-1  Bacteria  normal  0.173775  n/a   
 
 
-
 
NC_013061  Phep_1675  glucose-6-phosphate 1-dehydrogenase  49.2 
 
 
503 aa  491  1e-137  Pedobacter heparinus DSM 2366  Bacteria  normal  normal 
 
 
-
 
NC_009485  BBta_6317  glucose-6-phosphate 1-dehydrogenase  50.7 
 
 
507 aa  489  1e-137  Bradyrhizobium sp. BTAi1  Bacteria  normal  0.510788  normal 
 
 
-
 
NC_007925  RPC_3672  glucose-6-phosphate 1-dehydrogenase  51.32 
 
 
504 aa  490  1e-137  Rhodopseudomonas palustris BisB18  Bacteria  normal  normal 
 
 
-
 
NC_012793  GWCH70_2277  glucose-6-phosphate 1-dehydrogenase  49.17 
 
 
496 aa  486  1e-136  Geobacillus sp. WCH70  Bacteria  decreased coverage  0.000000172481  n/a   
 
 
-
 
NC_009484  Acry_1275  glucose-6-phosphate 1-dehydrogenase  51.61 
 
 
534 aa  486  1e-136  Acidiphilium cryptum JF-5  Bacteria  normal  0.685141  n/a   
 
 
-
 
NC_009475  BBta_p0094  glucose-6-phosphate 1-dehydrogenase  50.89 
 
 
508 aa  487  1e-136  Bradyrhizobium sp. BTAi1  Bacteria  n/a    normal  0.27048 
 
 
-
 
NC_008309  HS_1651  glucose-6-phosphate 1-dehydrogenase  50.51 
 
 
496 aa  486  1e-136  Haemophilus somnus 129PT  Bacteria  normal  n/a   
 
 
-
 
NC_013037  Dfer_5182  glucose-6-phosphate 1-dehydrogenase  47.19 
 
 
502 aa  485  1e-136  Dyadobacter fermentans DSM 18053  Bacteria  normal  0.875269  normal  0.100868 
 
 
-
 
NC_013132  Cpin_1481  glucose-6-phosphate 1-dehydrogenase  47.07 
 
 
501 aa  484  1e-135  Chitinophaga pinensis DSM 2588  Bacteria  hitchhiker  0.0000384376  normal  0.373558 
 
 
-
 
NC_010483  TRQ2_1661  glucose-6-phosphate 1-dehydrogenase  50.5 
 
 
496 aa  484  1e-135  Thermotoga sp. RQ2  Bacteria  normal  n/a   
 
 
-
 
NC_009456  VC0395_0341  glucose-6-phosphate 1-dehydrogenase  50.2 
 
 
501 aa  483  1e-135  Vibrio cholerae O395  Bacteria  decreased coverage  0.00000000308614  n/a   
 
 
-
 
NC_013456  VEA_003323  glucose-6-phosphate 1-dehydrogenase  49.8 
 
 
500 aa  484  1e-135  Vibrio sp. Ex25  Bacteria  normal  0.899023  n/a   
 
 
-
 
NC_010511  M446_6708  glucose-6-phosphate 1-dehydrogenase  51.87 
 
 
507 aa  480  1e-134  Methylobacterium sp. 4-46  Bacteria  normal  0.0735699  normal 
 
 
-
 
NC_007778  RPB_1890  glucose-6-phosphate 1-dehydrogenase  50.2 
 
 
504 aa  479  1e-134  Rhodopseudomonas palustris HaA2  Bacteria  normal  0.414124  normal 
 
 
-
 
NC_013205  Aaci_2551  glucose-6-phosphate 1-dehydrogenase  48.88 
 
 
520 aa  481  1e-134  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  0.269357  n/a   
 
 
-
 
NC_009783  VIBHAR_02429  glucose-6-phosphate 1-dehydrogenase  48.89 
 
 
526 aa  478  1e-134  Vibrio harveyi ATCC BAA-1116  Bacteria  n/a    n/a   
 
 
-
 
NC_007964  Nham_3271  glucose-6-phosphate 1-dehydrogenase  49.8 
 
 
504 aa  481  1e-134  Nitrobacter hamburgensis X14  Bacteria  normal  n/a   
 
 
-
 
NC_009486  Tpet_1595  glucose-6-phosphate 1-dehydrogenase  50.41 
 
 
496 aa  479  1e-134  Thermotoga petrophila RKU-1  Bacteria  normal  n/a   
 
 
-
 
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