82 homologs were found in PanDaTox collection
for query gene Bmur_0112 on replicon NC_014150
Organism: Brachyspira murdochii DSM 12563



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_014150  Bmur_0112  methylenetetrahydrofolate reductase  100 
 
 
306 aa  616  1e-175  Brachyspira murdochii DSM 12563  Bacteria  normal  n/a   
 
 
-
 
NC_013512  Sdel_0207  methylenetetrahydrofolate reductase  39.34 
 
 
304 aa  219  3.9999999999999997e-56  Sulfurospirillum deleyianum DSM 6946  Bacteria  hitchhiker  0.00833446  n/a   
 
 
-
 
NC_007575  Suden_1666  methylenetetrahydrofolate reductase  40 
 
 
303 aa  213  2.9999999999999995e-54  Sulfurimonas denitrificans DSM 1251  Bacteria  normal  n/a   
 
 
-
 
NC_007644  Moth_1191  methylenetetrahydrofolate reductase  29.84 
 
 
306 aa  127  3e-28  Moorella thermoacetica ATCC 39073  Bacteria  normal  0.211578  normal 
 
 
-
 
NC_007517  Gmet_0504  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  27.6 
 
 
605 aa  125  1e-27  Geobacter metallireducens GS-15  Bacteria  normal  0.0120544  normal 
 
 
-
 
NC_010320  Teth514_1210  methylenetetrahydrofolate reductase  31.25 
 
 
303 aa  121  1.9999999999999998e-26  Thermoanaerobacter sp. X514  Bacteria  hitchhiker  0.000000116637  n/a   
 
 
-
 
NC_007413  Ava_2992  methylenetetrahydrofolate reductase  27.48 
 
 
357 aa  118  1.9999999999999998e-25  Anabaena variabilis ATCC 29413  Bacteria  normal  0.0109931  normal  0.735442 
 
 
-
 
NC_008554  Sfum_3130  methylenetetrahydrofolate reductase  27.87 
 
 
310 aa  117  3e-25  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  normal 
 
 
-
 
NC_008816  A9601_01701  methylenetetrahydrofolate reductase  34.98 
 
 
296 aa  117  3e-25  Prochlorococcus marinus str. AS9601  Bacteria  normal  0.982527  n/a   
 
 
-
 
NC_010424  Daud_0880  methylenetetrahydrofolate reductase  26.26 
 
 
314 aa  115  1.0000000000000001e-24  Candidatus Desulforudis audaxviator MP104C  Bacteria  normal  0.958062  n/a   
 
 
-
 
NC_011884  Cyan7425_1687  methylenetetrahydrofolate reductase  27.61 
 
 
312 aa  114  2.0000000000000002e-24  Cyanothece sp. PCC 7425  Bacteria  normal  normal  0.634042 
 
 
-
 
NC_009091  P9301_01721  methylenetetrahydrofolate reductase  33.96 
 
 
296 aa  114  2.0000000000000002e-24  Prochlorococcus marinus str. MIT 9301  Bacteria  normal  n/a   
 
 
-
 
NC_010424  Daud_0117  methylenetetrahydrofolate reductase  29.77 
 
 
306 aa  113  4.0000000000000004e-24  Candidatus Desulforudis audaxviator MP104C  Bacteria  normal  n/a   
 
 
-
 
NC_011729  PCC7424_0350  methylenetetrahydrofolate reductase  29.51 
 
 
300 aa  113  4.0000000000000004e-24  Cyanothece sp. PCC 7424  Bacteria  n/a    normal 
 
 
-
 
NC_007577  PMT9312_0155  methylenetetrahydrofolate reductase  32.58 
 
 
296 aa  112  5e-24  Prochlorococcus marinus str. MIT 9312  Bacteria  normal  n/a   
 
 
-
 
NC_009636  Smed_1783  methylenetetrahydrofolate reductase  25.75 
 
 
367 aa  110  3e-23  Sinorhizobium medicae WSM419  Bacteria  normal  0.182207  hitchhiker  0.00669682 
 
 
-
 
NC_013161  Cyan8802_2074  methylenetetrahydrofolate reductase  29.33 
 
 
296 aa  110  3e-23  Cyanothece sp. PCC 8802  Bacteria  hitchhiker  0.00402744  normal 
 
 
-
 
NC_014248  Aazo_4669  methylenetetrahydrofolate reductase  27.76 
 
 
304 aa  110  3e-23  'Nostoc azollae' 0708  Bacteria  normal  n/a   
 
 
-
 
NC_012034  Athe_0325  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  29.79 
 
 
605 aa  110  4.0000000000000004e-23  Anaerocellum thermophilum DSM 6725  Bacteria  normal  n/a   
 
 
-
 
NC_009483  Gura_0708  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  29.81 
 
 
604 aa  110  4.0000000000000004e-23  Geobacter uraniireducens Rf4  Bacteria  normal  0.537957  n/a   
 
 
-
 
NC_011726  PCC8801_2050  methylenetetrahydrofolate reductase  28.81 
 
 
296 aa  109  6e-23  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_011146  Gbem_0613  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  28.14 
 
 
610 aa  109  6e-23  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_002939  GSU2974  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  28.98 
 
 
605 aa  109  7.000000000000001e-23  Geobacter sulfurreducens PCA  Bacteria  normal  n/a   
 
 
-
 
NC_009943  Dole_1151  methylenetetrahydrofolate reductase  27.78 
 
 
309 aa  109  7.000000000000001e-23  Desulfococcus oleovorans Hxd3  Bacteria  normal  n/a   
 
 
-
 
NC_013525  Tter_1187  homocysteine S-methyltransferase  26.97 
 
 
629 aa  109  7.000000000000001e-23  Thermobaculum terrenum ATCC BAA-798  Bacteria  n/a    n/a   
 
 
-
 
NC_012918  GM21_0627  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  26.1 
 
 
610 aa  108  1e-22  Geobacter sp. M21  Bacteria  n/a    unclonable  1.07944e-34 
 
 
-
 
NC_013385  Adeg_0345  methylenetetrahydrofolate reductase  26.76 
 
 
312 aa  107  2e-22  Ammonifex degensii KC4  Bacteria  normal  0.997494  n/a   
 
 
-
 
NC_007604  Synpcc7942_1309  hypothetical protein  27.3 
 
 
310 aa  107  3e-22  Synechococcus elongatus PCC 7942  Bacteria  normal  0.401481  normal 
 
 
-
 
NC_008819  NATL1_02251  methylenetetrahydrofolate reductase  31.37 
 
 
293 aa  106  6e-22  Prochlorococcus marinus str. NATL1A  Bacteria  normal  0.0232498  normal 
 
 
-
 
NC_011899  Hore_19580  methylenetetrahydrofolate reductase  27.39 
 
 
309 aa  105  7e-22  Halothermothrix orenii H 168  Bacteria  normal  n/a   
 
 
-
 
NC_008312  Tery_4692  methylenetetrahydrofolate reductase  27.45 
 
 
296 aa  105  8e-22  Trichodesmium erythraeum IMS101  Bacteria  normal  0.575485  normal 
 
 
-
 
NC_013216  Dtox_1285  methylenetetrahydrofolate reductase  27.36 
 
 
314 aa  105  1e-21  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  normal  0.354589 
 
 
-
 
NC_007513  Syncc9902_0288  hypothetical protein  27.27 
 
 
297 aa  104  2e-21  Synechococcus sp. CC9902  Bacteria  normal  n/a   
 
 
-
 
NC_007335  PMN2A_1519  methylenetetrahydrofolate reductase  30.98 
 
 
293 aa  103  4e-21  Prochlorococcus marinus str. NATL2A  Bacteria  normal  n/a   
 
 
-
 
NC_008817  P9515_01811  methylenetetrahydrofolate reductase  31.37 
 
 
296 aa  103  5e-21  Prochlorococcus marinus str. MIT 9515  Bacteria  normal  n/a   
 
 
-
 
NC_009943  Dole_0458  methylenetetrahydrofolate reductase  27.84 
 
 
321 aa  103  5e-21  Desulfococcus oleovorans Hxd3  Bacteria  normal  n/a   
 
 
-
 
NC_007498  Pcar_0238  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  26.19 
 
 
609 aa  102  8e-21  Pelobacter carbinolicus DSM 2380  Bacteria  normal  n/a   
 
 
-
 
NC_009483  Gura_1171  methylenetetrahydrofolate reductase  28.38 
 
 
297 aa  101  2e-20  Geobacter uraniireducens Rf4  Bacteria  normal  0.173306  n/a   
 
 
-
 
NC_011772  BCG9842_B0867  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  28.7 
 
 
610 aa  99  1e-19  Bacillus cereus G9842  Bacteria  normal  normal 
 
 
-
 
NC_011725  BCB4264_A4367  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  28.26 
 
 
610 aa  98.6  1e-19  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_005945  BAS4157  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  28.7 
 
 
610 aa  97.8  2e-19  Bacillus anthracis str. Sterne  Bacteria  normal  n/a   
 
 
-
 
NC_005957  BT9727_3996  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  28.7 
 
 
610 aa  97.8  2e-19  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  n/a   
 
 
-
 
NC_003909  BCE_4333  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  28.7 
 
 
610 aa  97.8  2e-19  Bacillus cereus ATCC 10987  Bacteria  normal  n/a   
 
 
-
 
NC_006274  BCZK4006  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  28.7 
 
 
610 aa  97.8  2e-19  Bacillus cereus E33L  Bacteria  normal  n/a   
 
 
-
 
NC_008609  Ppro_0283  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  27.76 
 
 
615 aa  97.4  2e-19  Pelobacter propionicus DSM 2379  Bacteria  normal  n/a   
 
 
-
 
NC_011658  BCAH187_A4386  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  28.7 
 
 
610 aa  97.8  2e-19  Bacillus cereus AH187  Bacteria  normal  n/a   
 
 
-
 
NC_010184  BcerKBAB4_4109  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  27.83 
 
 
610 aa  97.8  2e-19  Bacillus weihenstephanensis KBAB4  Bacteria  normal  n/a   
 
 
-
 
NC_007530  GBAA_4479  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  28.7 
 
 
610 aa  97.8  2e-19  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  n/a   
 
 
-
 
NC_011898  Ccel_2474  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  27.69 
 
 
615 aa  97.1  3e-19  Clostridium cellulolyticum H10  Bacteria  normal  n/a   
 
 
-
 
NC_011773  BCAH820_4275  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  28.7 
 
 
610 aa  97.1  3e-19  Bacillus cereus AH820  Bacteria  n/a    normal 
 
 
-
 
NC_002976  SERP0035  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  29.32 
 
 
612 aa  96.7  4e-19  Staphylococcus epidermidis RP62A  Bacteria  normal  n/a   
 
 
-
 
NC_009972  Haur_3632  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  26.38 
 
 
617 aa  95.9  8e-19  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  n/a   
 
 
-
 
NC_013173  Dbac_0626  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  25.22 
 
 
599 aa  95.9  8e-19  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  0.490063  n/a   
 
 
-
 
NC_011831  Cagg_1947  methylenetetrahydrofolate reductase  27.5 
 
 
307 aa  94.4  2e-18  Chloroflexus aggregans DSM 9485  Bacteria  normal  hitchhiker  0.00287398 
 
 
-
 
NC_007355  Mbar_A2312  methylenetetrahydrofolate reductase  26.25 
 
 
292 aa  94  3e-18  Methanosarcina barkeri str. Fusaro  Archaea  normal  normal 
 
 
-
 
NC_008148  Rxyl_0843  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  28.14 
 
 
611 aa  94  3e-18  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  n/a   
 
 
-
 
NC_007516  Syncc9605_2405  hypothetical protein  24.07 
 
 
301 aa  93.6  4e-18  Synechococcus sp. CC9605  Bacteria  normal  normal 
 
 
-
 
NC_004116  SAG2048  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  27.24 
 
 
614 aa  92.8  6e-18  Streptococcus agalactiae 2603V/R  Bacteria  normal  n/a   
 
 
-
 
NC_007517  Gmet_1160  methylenetetrahydrofolate reductase  25.84 
 
 
299 aa  92  1e-17  Geobacter metallireducens GS-15  Bacteria  hitchhiker  0.0000209189  normal  0.0125682 
 
 
-
 
NC_009976  P9211_01691  methylenetetrahydrofolate reductase  28.67 
 
 
309 aa  91.3  2e-17  Prochlorococcus marinus str. MIT 9211  Bacteria  normal  normal 
 
 
-
 
NC_009767  Rcas_3006  methylenetetrahydrofolate reductase  25.76 
 
 
309 aa  91.3  2e-17  Roseiflexus castenholzii DSM 13941  Bacteria  normal  normal 
 
 
-
 
NC_009674  Bcer98_2984  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  27.83 
 
 
614 aa  90.9  3e-17  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  n/a   
 
 
-
 
NC_009632  SaurJH1_0415  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  27.64 
 
 
613 aa  89.7  5e-17  Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  n/a   
 
 
-
 
NC_009487  SaurJH9_0405  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  27.64 
 
 
613 aa  89.7  5e-17  Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  n/a   
 
 
-
 
NC_008820  P9303_26821  methylenetetrahydrofolate reductase  25.52 
 
 
298 aa  89.7  5e-17  Prochlorococcus marinus str. MIT 9303  Bacteria  n/a    normal 
 
 
-
 
NC_013205  Aaci_1583  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  24.61 
 
 
637 aa  89.7  6e-17  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  n/a   
 
 
-
 
NC_008009  Acid345_3426  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  27.51 
 
 
617 aa  89  1e-16  Candidatus Koribacter versatilis Ellin345  Bacteria  normal  0.41819  normal 
 
 
-
 
NC_007955  Mbur_1847  methylenetetrahydrofolate reductase  24.08 
 
 
294 aa  87.4  3e-16  Methanococcoides burtonii DSM 6242  Archaea  normal  n/a   
 
 
-
 
NC_009523  RoseRS_2032  methylenetetrahydrofolate reductase  25.68 
 
 
309 aa  85.1  0.000000000000001  Roseiflexus sp. RS-1  Bacteria  normal  normal  0.264771 
 
 
-
 
NC_009253  Dred_1750  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  27.37 
 
 
598 aa  85.5  0.000000000000001  Desulfotomaculum reducens MI-1  Bacteria  normal  n/a   
 
 
-
 
NC_013411  GYMC61_1524  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  25.38 
 
 
615 aa  84.7  0.000000000000002  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_012793  GWCH70_0708  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  24.81 
 
 
616 aa  82.8  0.000000000000007  Geobacillus sp. WCH70  Bacteria  normal  0.0266464  n/a   
 
 
-
 
NC_002939  GSU0860  methylenetetrahydrofolate reductase family protein  23.13 
 
 
301 aa  82  0.00000000000001  Geobacter sulfurreducens PCA  Bacteria  normal  0.0656354  n/a   
 
 
-
 
NC_013440  Hoch_4784  homocysteine S-methyltransferase  23.08 
 
 
643 aa  73.6  0.000000000004  Haliangium ochraceum DSM 14365  Bacteria  normal  normal 
 
 
-
 
NC_011661  Dtur_1634  methylenetetrahydrofolate reductase  26.25 
 
 
288 aa  57.4  0.0000003  Dictyoglomus turgidum DSM 6724  Bacteria  normal  n/a   
 
 
-
 
NC_009486  Tpet_0654  methylenetetrahydrofolate reductase  25.12 
 
 
281 aa  53.5  0.000004  Thermotoga petrophila RKU-1  Bacteria  normal  0.495611  n/a   
 
 
-
 
NC_010483  TRQ2_0678  methylenetetrahydrofolate reductase  25.58 
 
 
281 aa  52.8  0.000008  Thermotoga sp. RQ2  Bacteria  normal  0.431353  n/a   
 
 
-
 
NC_013131  Caci_1041  methylenetetrahydrofolate reductase  23.97 
 
 
259 aa  47.8  0.0002  Catenulispora acidiphila DSM 44928  Bacteria  normal  0.569103  normal  0.0517108 
 
 
-
 
NC_009921  Franean1_6374  methylenetetrahydrofolate reductase  20.34 
 
 
257 aa  45.1  0.002  Frankia sp. EAN1pec  Bacteria  normal  normal 
 
 
-
 
NC_011830  Dhaf_0077  methylenetetrahydrofolate reductase  21.64 
 
 
523 aa  44.7  0.002  Desulfitobacterium hafniense DCB-2  Bacteria  normal  0.026551  n/a   
 
 
-
 
NC_009045  PICST_83803  predicted protein  31.25 
 
 
635 aa  43.1  0.006  Scheffersomyces stipitis CBS 6054  Eukaryota  normal  0.163002  decreased coverage  0.000293877 
 
 
-
 
NC_013595  Sros_8985  5 10-methylenetetrahydrofolate reductase-like protein  23.53 
 
 
259 aa  42.7  0.007  Streptosporangium roseum DSM 43021  Bacteria  normal  normal 
 
 
-
 
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