81 homologs were found in PanDaTox collection
for query gene Mflv_3461 on replicon NC_009338
Organism: Mycobacterium gilvum PYR-GCK



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_009338  Mflv_3461  methylenetetrahydrofolate reductase  100 
 
 
333 aa  653    Mycobacterium gilvum PYR-GCK  Bacteria  normal  normal  0.477393 
 
 
-
 
NC_009077  Mjls_1517  methylenetetrahydrofolate reductase  80.44 
 
 
327 aa  467  9.999999999999999e-131  Mycobacterium sp. JLS  Bacteria  normal  normal 
 
 
-
 
NC_008705  Mkms_1569  methylenetetrahydrofolate reductase  79.5 
 
 
327 aa  463  1e-129  Mycobacterium sp. KMS  Bacteria  normal  normal 
 
 
-
 
NC_008146  Mmcs_1546  methylenetetrahydrofolate reductase  79.5 
 
 
327 aa  463  1e-129  Mycobacterium sp. MCS  Bacteria  normal  0.50518  n/a   
 
 
-
 
NC_013385  Adeg_0345  methylenetetrahydrofolate reductase  31.96 
 
 
312 aa  99.4  7e-20  Ammonifex degensii KC4  Bacteria  normal  0.997494  n/a   
 
 
-
 
NC_010424  Daud_0117  methylenetetrahydrofolate reductase  32.55 
 
 
306 aa  92.4  1e-17  Candidatus Desulforudis audaxviator MP104C  Bacteria  normal  n/a   
 
 
-
 
NC_010424  Daud_0880  methylenetetrahydrofolate reductase  32.41 
 
 
314 aa  92.4  1e-17  Candidatus Desulforudis audaxviator MP104C  Bacteria  normal  0.958062  n/a   
 
 
-
 
NC_007644  Moth_1191  methylenetetrahydrofolate reductase  26.59 
 
 
306 aa  90.5  4e-17  Moorella thermoacetica ATCC 39073  Bacteria  normal  0.211578  normal 
 
 
-
 
NC_007577  PMT9312_0155  methylenetetrahydrofolate reductase  28.85 
 
 
296 aa  89.7  6e-17  Prochlorococcus marinus str. MIT 9312  Bacteria  normal  n/a   
 
 
-
 
NC_009091  P9301_01721  methylenetetrahydrofolate reductase  28.77 
 
 
296 aa  87.4  3e-16  Prochlorococcus marinus str. MIT 9301  Bacteria  normal  n/a   
 
 
-
 
NC_009636  Smed_1783  methylenetetrahydrofolate reductase  27.91 
 
 
367 aa  87.4  3e-16  Sinorhizobium medicae WSM419  Bacteria  normal  0.182207  hitchhiker  0.00669682 
 
 
-
 
NC_008816  A9601_01701  methylenetetrahydrofolate reductase  27.83 
 
 
296 aa  82.8  0.000000000000008  Prochlorococcus marinus str. AS9601  Bacteria  normal  0.982527  n/a   
 
 
-
 
NC_013216  Dtox_1285  methylenetetrahydrofolate reductase  26.55 
 
 
314 aa  80.5  0.00000000000003  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  normal  0.354589 
 
 
-
 
NC_008819  NATL1_02251  methylenetetrahydrofolate reductase  28.85 
 
 
293 aa  80.9  0.00000000000003  Prochlorococcus marinus str. NATL1A  Bacteria  normal  0.0232498  normal 
 
 
-
 
NC_011831  Cagg_1947  methylenetetrahydrofolate reductase  30.52 
 
 
307 aa  77.8  0.0000000000002  Chloroflexus aggregans DSM 9485  Bacteria  normal  hitchhiker  0.00287398 
 
 
-
 
NC_007335  PMN2A_1519  methylenetetrahydrofolate reductase  28.37 
 
 
293 aa  77.8  0.0000000000003  Prochlorococcus marinus str. NATL2A  Bacteria  normal  n/a   
 
 
-
 
NC_008817  P9515_01811  methylenetetrahydrofolate reductase  25 
 
 
296 aa  77  0.0000000000004  Prochlorococcus marinus str. MIT 9515  Bacteria  normal  n/a   
 
 
-
 
NC_009976  P9211_01691  methylenetetrahydrofolate reductase  28.04 
 
 
309 aa  75.9  0.0000000000009  Prochlorococcus marinus str. MIT 9211  Bacteria  normal  normal 
 
 
-
 
NC_008554  Sfum_3130  methylenetetrahydrofolate reductase  25.5 
 
 
310 aa  75.9  0.0000000000009  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  normal 
 
 
-
 
NC_009943  Dole_0458  methylenetetrahydrofolate reductase  26.36 
 
 
321 aa  75.1  0.000000000002  Desulfococcus oleovorans Hxd3  Bacteria  normal  n/a   
 
 
-
 
NC_007513  Syncc9902_0288  hypothetical protein  29.22 
 
 
297 aa  75.1  0.000000000002  Synechococcus sp. CC9902  Bacteria  normal  n/a   
 
 
-
 
NC_011884  Cyan7425_1687  methylenetetrahydrofolate reductase  26 
 
 
312 aa  74.3  0.000000000002  Cyanothece sp. PCC 7425  Bacteria  normal  normal  0.634042 
 
 
-
 
NC_009523  RoseRS_2032  methylenetetrahydrofolate reductase  29.86 
 
 
309 aa  73.9  0.000000000003  Roseiflexus sp. RS-1  Bacteria  normal  normal  0.264771 
 
 
-
 
NC_009767  Rcas_3006  methylenetetrahydrofolate reductase  30.33 
 
 
309 aa  74.3  0.000000000003  Roseiflexus castenholzii DSM 13941  Bacteria  normal  normal 
 
 
-
 
NC_008820  P9303_26821  methylenetetrahydrofolate reductase  27.4 
 
 
298 aa  73.9  0.000000000004  Prochlorococcus marinus str. MIT 9303  Bacteria  n/a    normal 
 
 
-
 
NC_007516  Syncc9605_2405  hypothetical protein  27.76 
 
 
301 aa  73.2  0.000000000006  Synechococcus sp. CC9605  Bacteria  normal  normal 
 
 
-
 
NC_007413  Ava_2992  methylenetetrahydrofolate reductase  26.96 
 
 
357 aa  71.2  0.00000000002  Anabaena variabilis ATCC 29413  Bacteria  normal  0.0109931  normal  0.735442 
 
 
-
 
NC_013161  Cyan8802_2074  methylenetetrahydrofolate reductase  25.58 
 
 
296 aa  71.2  0.00000000002  Cyanothece sp. PCC 8802  Bacteria  hitchhiker  0.00402744  normal 
 
 
-
 
NC_014248  Aazo_4669  methylenetetrahydrofolate reductase  26.92 
 
 
304 aa  71.2  0.00000000002  'Nostoc azollae' 0708  Bacteria  normal  n/a   
 
 
-
 
NC_011726  PCC8801_2050  methylenetetrahydrofolate reductase  25.58 
 
 
296 aa  70.9  0.00000000003  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_007355  Mbar_A2312  methylenetetrahydrofolate reductase  27.35 
 
 
292 aa  70.5  0.00000000004  Methanosarcina barkeri str. Fusaro  Archaea  normal  normal 
 
 
-
 
NC_007517  Gmet_1160  methylenetetrahydrofolate reductase  27.46 
 
 
299 aa  70.5  0.00000000004  Geobacter metallireducens GS-15  Bacteria  hitchhiker  0.0000209189  normal  0.0125682 
 
 
-
 
NC_008312  Tery_4692  methylenetetrahydrofolate reductase  25.24 
 
 
296 aa  69.7  0.00000000006  Trichodesmium erythraeum IMS101  Bacteria  normal  0.575485  normal 
 
 
-
 
NC_007604  Synpcc7942_1309  hypothetical protein  29.41 
 
 
310 aa  69.3  0.00000000008  Synechococcus elongatus PCC 7942  Bacteria  normal  0.401481  normal 
 
 
-
 
NC_002939  GSU0860  methylenetetrahydrofolate reductase family protein  26.69 
 
 
301 aa  68.2  0.0000000002  Geobacter sulfurreducens PCA  Bacteria  normal  0.0656354  n/a   
 
 
-
 
NC_009483  Gura_1171  methylenetetrahydrofolate reductase  26.94 
 
 
297 aa  67.8  0.0000000003  Geobacter uraniireducens Rf4  Bacteria  normal  0.173306  n/a   
 
 
-
 
NC_009943  Dole_1151  methylenetetrahydrofolate reductase  22.48 
 
 
309 aa  65.9  0.000000001  Desulfococcus oleovorans Hxd3  Bacteria  normal  n/a   
 
 
-
 
NC_007955  Mbur_1847  methylenetetrahydrofolate reductase  26.5 
 
 
294 aa  64.7  0.000000002  Methanococcoides burtonii DSM 6242  Archaea  normal  n/a   
 
 
-
 
NC_011729  PCC7424_0350  methylenetetrahydrofolate reductase  24.26 
 
 
300 aa  64.7  0.000000002  Cyanothece sp. PCC 7424  Bacteria  n/a    normal 
 
 
-
 
NC_013205  Aaci_1583  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  27.86 
 
 
637 aa  64.3  0.000000003  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  n/a   
 
 
-
 
NC_008009  Acid345_3426  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  25.76 
 
 
617 aa  62.4  0.00000001  Candidatus Koribacter versatilis Ellin345  Bacteria  normal  0.41819  normal 
 
 
-
 
NC_012793  GWCH70_0708  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  27.14 
 
 
616 aa  58.5  0.0000001  Geobacillus sp. WCH70  Bacteria  normal  0.0266464  n/a   
 
 
-
 
NC_002939  GSU2974  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  26.7 
 
 
605 aa  57.8  0.0000003  Geobacter sulfurreducens PCA  Bacteria  normal  n/a   
 
 
-
 
NC_012918  GM21_0627  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  26.21 
 
 
610 aa  56.6  0.0000005  Geobacter sp. M21  Bacteria  n/a    unclonable  1.07944e-34 
 
 
-
 
NC_013440  Hoch_4784  homocysteine S-methyltransferase  26.98 
 
 
643 aa  55.5  0.000001  Haliangium ochraceum DSM 14365  Bacteria  normal  normal 
 
 
-
 
NC_013411  GYMC61_1524  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  25.7 
 
 
615 aa  55.5  0.000001  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_012034  Athe_0325  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  23.88 
 
 
605 aa  55.5  0.000001  Anaerocellum thermophilum DSM 6725  Bacteria  normal  n/a   
 
 
-
 
NC_009632  SaurJH1_0415  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  39.06 
 
 
613 aa  54.7  0.000002  Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  n/a   
 
 
-
 
NC_009487  SaurJH9_0405  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  39.06 
 
 
613 aa  54.7  0.000002  Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  n/a   
 
 
-
 
NC_011146  Gbem_0613  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  25.73 
 
 
610 aa  54.3  0.000003  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_011830  Dhaf_0077  methylenetetrahydrofolate reductase  23.38 
 
 
523 aa  54.3  0.000003  Desulfitobacterium hafniense DCB-2  Bacteria  normal  0.026551  n/a   
 
 
-
 
NC_002976  SERP0035  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  39.68 
 
 
612 aa  53.9  0.000004  Staphylococcus epidermidis RP62A  Bacteria  normal  n/a   
 
 
-
 
NC_008609  Ppro_0283  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  26.7 
 
 
615 aa  53.9  0.000004  Pelobacter propionicus DSM 2379  Bacteria  normal  n/a   
 
 
-
 
NC_009483  Gura_0708  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  35.53 
 
 
604 aa  53.5  0.000005  Geobacter uraniireducens Rf4  Bacteria  normal  0.537957  n/a   
 
 
-
 
NC_011899  Hore_19580  methylenetetrahydrofolate reductase  47.54 
 
 
309 aa  53.1  0.000007  Halothermothrix orenii H 168  Bacteria  normal  n/a   
 
 
-
 
NC_011661  Dtur_1634  methylenetetrahydrofolate reductase  35.35 
 
 
288 aa  52.4  0.00001  Dictyoglomus turgidum DSM 6724  Bacteria  normal  n/a   
 
 
-
 
NC_007517  Gmet_0504  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  36.23 
 
 
605 aa  51.2  0.00002  Geobacter metallireducens GS-15  Bacteria  normal  0.0120544  normal 
 
 
-
 
NC_004116  SAG2048  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  24.07 
 
 
614 aa  51.6  0.00002  Streptococcus agalactiae 2603V/R  Bacteria  normal  n/a   
 
 
-
 
NC_013173  Dbac_1758  5,10-methylenetetrahydrofolate reductase  29.61 
 
 
295 aa  48.5  0.0001  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  n/a   
 
 
-
 
NC_013530  Xcel_0051  Methylenetetrahydrofolate reductase (NAD(P)H)  35.51 
 
 
323 aa  47.8  0.0002  Xylanimonas cellulosilytica DSM 15894  Bacteria  normal  0.756837  n/a   
 
 
-
 
NC_007498  Pcar_0238  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  25.63 
 
 
609 aa  47.4  0.0003  Pelobacter carbinolicus DSM 2380  Bacteria  normal  n/a   
 
 
-
 
NC_013525  Tter_1187  homocysteine S-methyltransferase  21.98 
 
 
629 aa  46.6  0.0006  Thermobaculum terrenum ATCC BAA-798  Bacteria  n/a    n/a   
 
 
-
 
NC_003909  BCE_4333  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  25.35 
 
 
610 aa  46.6  0.0006  Bacillus cereus ATCC 10987  Bacteria  normal  n/a   
 
 
-
 
NC_011773  BCAH820_4275  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  24.88 
 
 
610 aa  46.2  0.0007  Bacillus cereus AH820  Bacteria  n/a    normal 
 
 
-
 
NC_007530  GBAA_4479  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  24.88 
 
 
610 aa  46.2  0.0008  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  n/a   
 
 
-
 
NC_005945  BAS4157  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  24.88 
 
 
610 aa  46.2  0.0008  Bacillus anthracis str. Sterne  Bacteria  normal  n/a   
 
 
-
 
NC_006274  BCZK4006  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  24.88 
 
 
610 aa  46.2  0.0008  Bacillus cereus E33L  Bacteria  normal  n/a   
 
 
-
 
NC_005957  BT9727_3996  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  24.88 
 
 
610 aa  46.2  0.0008  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  n/a   
 
 
-
 
NC_011772  BCG9842_B0867  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  33.33 
 
 
610 aa  46.2  0.0009  Bacillus cereus G9842  Bacteria  normal  normal 
 
 
-
 
NC_010184  BcerKBAB4_4109  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  35.06 
 
 
610 aa  46.2  0.0009  Bacillus weihenstephanensis KBAB4  Bacteria  normal  n/a   
 
 
-
 
NC_011658  BCAH187_A4386  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  33.33 
 
 
610 aa  45.8  0.0009  Bacillus cereus AH187  Bacteria  normal  n/a   
 
 
-
 
NC_011725  BCB4264_A4367  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  35.06 
 
 
610 aa  46.2  0.0009  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_013521  Sked_00590  5,10-methylenetetrahydrofolate reductase  25.97 
 
 
354 aa  45.8  0.001  Sanguibacter keddieii DSM 10542  Bacteria  normal  normal  0.0768874 
 
 
-
 
NC_009674  Bcer98_2984  bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein  32.14 
 
 
614 aa  45.4  0.001  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  n/a   
 
 
-
 
NC_009718  Fnod_1279  methylenetetrahydrofolate reductase (NAD(P)H)  27.92 
 
 
313 aa  45.1  0.002  Fervidobacterium nodosum Rt17-B1  Bacteria  normal  n/a   
 
 
-
 
NC_010483  TRQ2_0678  methylenetetrahydrofolate reductase  21.98 
 
 
281 aa  44.3  0.003  Thermotoga sp. RQ2  Bacteria  normal  0.431353  n/a   
 
 
-
 
NC_008048  Sala_0035  5,10-methylenetetrahydrofolate reductase  27.53 
 
 
312 aa  43.5  0.005  Sphingopyxis alaskensis RB2256  Bacteria  normal  normal  0.116198 
 
 
-
 
NC_013174  Jden_0190  Methylenetetrahydrofolate reductase (NAD(P)H)  35.05 
 
 
339 aa  43.1  0.006  Jonesia denitrificans DSM 20603  Bacteria  normal  0.419014  normal 
 
 
-
 
NC_010571  Oter_4335  methylenetetrahydrofolate reductase  24.49 
 
 
538 aa  43.1  0.007  Opitutus terrae PB90-1  Bacteria  normal  0.359645  normal 
 
 
-
 
NC_011886  Achl_2125  Methylenetetrahydrofolate reductase (NAD(P)H)  25.73 
 
 
320 aa  42.7  0.008  Arthrobacter chlorophenolicus A6  Bacteria  n/a    hitchhiker  0.000000980876 
 
 
-
 
NC_008541  Arth_2367  Deleted entry  26.32 
 
 
323 aa  42.7  0.009  Arthrobacter sp. FB24  Bacteria  normal  0.38264  n/a   
 
 
-
 
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