More than 300 homologs were found in PanDaTox collection
for query gene VC0395_A1460 on replicon NC_009457
Organism: Vibrio cholerae O395



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_009457  VC0395_A1460  pyruvate formate lyase-activating enzyme 1  100 
 
 
246 aa  517  1e-146  Vibrio cholerae O395  Bacteria  normal  n/a   
 
 
-
 
NC_013456  VEA_003978  pyruvate formate-lyase activating enzyme  86.59 
 
 
246 aa  457  9.999999999999999e-129  Vibrio sp. Ex25  Bacteria  normal  n/a   
 
 
-
 
NC_011312  VSAL_I1953  pyruvate formate lyase-activating enzyme 1  81.56 
 
 
245 aa  442  1e-123  Aliivibrio salmonicida LFI1238  Bacteria  normal  n/a   
 
 
-
 
NC_012917  PC1_1728  pyruvate formate lyase-activating enzyme 1  75.2 
 
 
246 aa  407  1.0000000000000001e-112  Pectobacterium carotovorum subsp. carotovorum PC1  Bacteria  normal  0.548183  n/a   
 
 
-
 
NC_013421  Pecwa_1996  pyruvate formate lyase-activating enzyme 1  74.8 
 
 
246 aa  405  1.0000000000000001e-112  Pectobacterium wasabiae WPP163  Bacteria  normal  n/a   
 
 
-
 
NC_009436  Ent638_1422  pyruvate formate lyase-activating enzyme 1  73.98 
 
 
246 aa  400  1e-111  Enterobacter sp. 638  Bacteria  normal  normal 
 
 
-
 
NC_010498  EcSMS35_2219  pyruvate formate lyase-activating enzyme 1  73.58 
 
 
246 aa  398  9.999999999999999e-111  Escherichia coli SMS-3-5  Bacteria  normal  normal  0.542279 
 
 
-
 
CP001509  ECD_00906  pyruvate formate lyase activating enzyme 1  73.58 
 
 
246 aa  398  9.999999999999999e-111  Escherichia coli BL21(DE3)  Bacteria  normal  0.84876  n/a   
 
 
-
 
CP001637  EcDH1_2741  pyruvate formate-lyase activating enzyme  73.58 
 
 
246 aa  398  9.999999999999999e-111  Escherichia coli DH1  Bacteria  normal  n/a   
 
 
-
 
NC_009800  EcHS_A1008  pyruvate formate lyase-activating enzyme 1  73.58 
 
 
246 aa  398  9.999999999999999e-111  Escherichia coli HS  Bacteria  normal  0.312248  n/a   
 
 
-
 
NC_010468  EcolC_2694  pyruvate formate lyase-activating enzyme 1  73.58 
 
 
246 aa  398  9.999999999999999e-111  Escherichia coli ATCC 8739  Bacteria  normal  normal  0.489101 
 
 
-
 
NC_010658  SbBS512_E2426  pyruvate formate lyase-activating enzyme 1  73.58 
 
 
255 aa  397  9.999999999999999e-111  Shigella boydii CDC 3083-94  Bacteria  normal  0.0764987  n/a   
 
 
-
 
NC_012892  B21_00913  hypothetical protein  73.58 
 
 
246 aa  398  9.999999999999999e-111  Escherichia coli BL21  Bacteria  normal  0.880778  n/a   
 
 
-
 
NC_011353  ECH74115_1063  pyruvate formate lyase-activating enzyme 1  73.58 
 
 
246 aa  398  9.999999999999999e-111  Escherichia coli O157:H7 str. EC4115  Bacteria  normal  normal 
 
 
-
 
NC_011149  SeAg_B0975  pyruvate formate lyase-activating enzyme 1  73.25 
 
 
265 aa  394  1e-109  Salmonella enterica subsp. enterica serovar Agona str. SL483  Bacteria  normal  0.462536  n/a   
 
 
-
 
NC_011083  SeHA_C1068  pyruvate formate lyase-activating enzyme 1  73.25 
 
 
265 aa  394  1e-109  Salmonella enterica subsp. enterica serovar Heidelberg str. SL476  Bacteria  normal  normal  0.763935 
 
 
-
 
NC_011094  SeSA_A1083  pyruvate formate lyase-activating enzyme 1  73.25 
 
 
265 aa  394  1e-109  Salmonella enterica subsp. enterica serovar Schwarzengrund str. CVM19633  Bacteria  normal  0.704189  normal 
 
 
-
 
NC_009708  YpsIP31758_2591  pyruvate formate lyase-activating enzyme 1  74.49 
 
 
244 aa  396  1e-109  Yersinia pseudotuberculosis IP 31758  Bacteria  normal  n/a   
 
 
-
 
NC_011205  SeD_A1034  pyruvate formate lyase-activating enzyme 1  73.25 
 
 
265 aa  394  1e-109  Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853  Bacteria  normal  0.633483  normal  0.712061 
 
 
-
 
NC_010465  YPK_2679  pyruvate formate lyase-activating enzyme 1  74.49 
 
 
265 aa  396  1e-109  Yersinia pseudotuberculosis YPIII  Bacteria  normal  n/a   
 
 
-
 
NC_010159  YpAngola_A1618  pyruvate formate lyase-activating enzyme 1  74.49 
 
 
244 aa  396  1e-109  Yersinia pestis Angola  Bacteria  normal  0.344326  normal 
 
 
-
 
NC_009801  EcE24377A_0980  pyruvate formate lyase-activating enzyme 1  73.47 
 
 
265 aa  397  1e-109  Escherichia coli E24377A  Bacteria  normal  0.777271  n/a   
 
 
-
 
NC_011080  SNSL254_A1003  pyruvate formate lyase-activating enzyme 1  73.25 
 
 
265 aa  394  1e-109  Salmonella enterica subsp. enterica serovar Newport str. SL254  Bacteria  normal  normal 
 
 
-
 
NC_012912  Dd1591_2346  pyruvate formate lyase-activating enzyme 1  71.95 
 
 
246 aa  392  1e-108  Dickeya zeae Ech1591  Bacteria  normal  n/a   
 
 
-
 
NC_009832  Spro_1701  pyruvate formate lyase-activating enzyme 1  72.76 
 
 
246 aa  392  1e-108  Serratia proteamaculans 568  Bacteria  normal  normal  0.276107 
 
 
-
 
NC_009783  VIBHAR_01544  pyruvate formate-lyase 1 activating enzyme  83.26 
 
 
215 aa  390  1e-107  Vibrio harveyi ATCC BAA-1116  Bacteria  n/a    n/a   
 
 
-
 
NC_012880  Dd703_2245  pyruvate formate lyase-activating enzyme 1  71.14 
 
 
246 aa  389  1e-107  Dickeya dadantii Ech703  Bacteria  normal  n/a   
 
 
-
 
NC_009438  Sputcn32_2379  pyruvate formate lyase-activating enzyme 1  67.48 
 
 
246 aa  355  2.9999999999999997e-97  Shewanella putrefaciens CN-32  Bacteria  normal  0.0648375  n/a   
 
 
-
 
NC_008309  HS_1147  pyruvate formate lyase-activating enzyme 1  67.07 
 
 
246 aa  352  2e-96  Haemophilus somnus 129PT  Bacteria  normal  0.223371  n/a   
 
 
-
 
NC_004347  SO_2913  pyruvate formate lyase-activating enzyme 1  66.67 
 
 
246 aa  352  2.9999999999999997e-96  Shewanella oneidensis MR-1  Bacteria  n/a    n/a   
 
 
-
 
NC_008322  Shewmr7_1560  pyruvate formate lyase-activating enzyme 1  66.26 
 
 
246 aa  351  5.9999999999999994e-96  Shewanella sp. MR-7  Bacteria  normal  0.0861855  normal  0.127939 
 
 
-
 
NC_008709  Ping_3308  pyruvate formate lyase-activating enzyme 1  66.67 
 
 
246 aa  351  5.9999999999999994e-96  Psychromonas ingrahamii 37  Bacteria  normal  0.760643  normal 
 
 
-
 
NC_008577  Shewana3_1554  pyruvate formate lyase-activating enzyme 1  66.26 
 
 
246 aa  350  8e-96  Shewanella sp. ANA-3  Bacteria  normal  normal  0.202343 
 
 
-
 
NC_008321  Shewmr4_1493  pyruvate formate lyase-activating enzyme 1  65.85 
 
 
246 aa  350  8.999999999999999e-96  Shewanella sp. MR-4  Bacteria  normal  0.0621061  normal  0.601453 
 
 
-
 
NC_009052  Sbal_2672  pyruvate formate lyase-activating enzyme 1  66.26 
 
 
246 aa  350  1e-95  Shewanella baltica OS155  Bacteria  normal  0.209524  n/a   
 
 
-
 
NC_009997  Sbal195_2770  pyruvate formate lyase-activating enzyme 1  66.26 
 
 
246 aa  349  3e-95  Shewanella baltica OS195  Bacteria  normal  0.789492  normal  0.831123 
 
 
-
 
NC_011663  Sbal223_1693  pyruvate formate lyase-activating enzyme 1  66.26 
 
 
246 aa  349  3e-95  Shewanella baltica OS223  Bacteria  hitchhiker  0.00927712  hitchhiker  0.00567391 
 
 
-
 
NC_009665  Shew185_2691  pyruvate formate lyase-activating enzyme 1  66.26 
 
 
246 aa  349  3e-95  Shewanella baltica OS185  Bacteria  hitchhiker  0.00335137  n/a   
 
 
-
 
NC_009901  Spea_1671  pyruvate formate lyase-activating enzyme 1  63.41 
 
 
246 aa  342  4e-93  Shewanella pealeana ATCC 700345  Bacteria  normal  0.0803873  n/a   
 
 
-
 
NC_009831  Ssed_1707  pyruvate formate lyase-activating enzyme 1  65.04 
 
 
246 aa  341  5.999999999999999e-93  Shewanella sediminis HAW-EB3  Bacteria  normal  normal  0.0231805 
 
 
-
 
NC_008700  Sama_1497  pyruvate formate lyase-activating enzyme 1  62.6 
 
 
246 aa  340  1e-92  Shewanella amazonensis SB2B  Bacteria  normal  normal 
 
 
-
 
NC_010506  Swoo_2884  pyruvate formate lyase-activating enzyme 1  63.41 
 
 
246 aa  338  4e-92  Shewanella woodyi ATCC 51908  Bacteria  hitchhiker  0.00506631  hitchhiker  0.00000444162 
 
 
-
 
NC_009092  Shew_2391  pyruvate formate lyase-activating enzyme 1  66.52 
 
 
246 aa  337  9.999999999999999e-92  Shewanella loihica PV-4  Bacteria  normal  0.227753  normal  0.208715 
 
 
-
 
NC_007954  Sden_2407  pyruvate formate lyase-activating enzyme 1  61.48 
 
 
245 aa  327  8e-89  Shewanella denitrificans OS217  Bacteria  normal  n/a   
 
 
-
 
NC_008345  Sfri_2474  pyruvate formate lyase-activating enzyme 1  64.07 
 
 
245 aa  325  6e-88  Shewanella frigidimarina NCIMB 400  Bacteria  normal  n/a   
 
 
-
 
NC_012793  GWCH70_3391  pyruvate formate-lyase activating enzyme  50.63 
 
 
249 aa  267  1e-70  Geobacillus sp. WCH70  Bacteria  normal  n/a   
 
 
-
 
NC_005957  BT9727_0425  formate acetyltransferase activating enzyme (pyruvate formate-lyase activating enzyme)  49.58 
 
 
243 aa  263  1e-69  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  n/a   
 
 
-
 
NC_011725  BCB4264_A0513  pyruvate formate-lyase-activating enzyme  49.16 
 
 
243 aa  263  2e-69  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_010184  BcerKBAB4_0427  pyruvate formate-lyase activating enzyme  50 
 
 
243 aa  263  2e-69  Bacillus weihenstephanensis KBAB4  Bacteria  normal  n/a   
 
 
-
 
NC_005945  BAS0482  pyruvate formate-lyase-activating enzyme  49.58 
 
 
243 aa  263  2e-69  Bacillus anthracis str. Sterne  Bacteria  normal  n/a   
 
 
-
 
NC_011773  BCAH820_0491  pyruvate formate-lyase-activating enzyme  49.58 
 
 
243 aa  263  2e-69  Bacillus cereus AH820  Bacteria  n/a    normal 
 
 
-
 
NC_007530  GBAA_0510  pyruvate formate-lyase-activating enzyme  49.58 
 
 
243 aa  263  2e-69  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  n/a   
 
 
-
 
NC_009012  Cthe_0506  pyruvate formate-lyase activating enzyme  51.48 
 
 
238 aa  263  3e-69  Clostridium thermocellum ATCC 27405  Bacteria  normal  0.0339577  n/a   
 
 
-
 
NC_006274  BCZK0421  formate acetyltransferase activating enzyme (pyruvate formate-lyase activating enzyme)  49.16 
 
 
243 aa  261  4.999999999999999e-69  Bacillus cereus E33L  Bacteria  normal  n/a   
 
 
-
 
NC_011898  Ccel_2581  pyruvate formate-lyase activating enzyme  51.48 
 
 
240 aa  262  4.999999999999999e-69  Clostridium cellulolyticum H10  Bacteria  normal  n/a   
 
 
-
 
NC_003909  BCE_0564  pyruvate formate-lyase-activating enzyme  49.16 
 
 
243 aa  261  6.999999999999999e-69  Bacillus cereus ATCC 10987  Bacteria  normal  n/a   
 
 
-
 
NC_011658  BCAH187_A0566  pyruvate formate-lyase-activating enzyme  49.16 
 
 
243 aa  261  6.999999999999999e-69  Bacillus cereus AH187  Bacteria  normal  n/a   
 
 
-
 
NC_011772  BCG9842_B4810  pyruvate formate-lyase-activating enzyme  48.74 
 
 
243 aa  261  8.999999999999999e-69  Bacillus cereus G9842  Bacteria  normal  normal 
 
 
-
 
NC_009674  Bcer98_0432  pyruvate formate-lyase activating enzyme  49.57 
 
 
243 aa  258  9e-68  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  n/a   
 
 
-
 
NC_011899  Hore_23160  pyruvate formate-lyase activating enzyme  49.16 
 
 
247 aa  248  9e-65  Halothermothrix orenii H 168  Bacteria  normal  n/a   
 
 
-
 
NC_010001  Cphy_2820  pyruvate formate-lyase activating enzyme  52.02 
 
 
250 aa  242  5e-63  Clostridium phytofermentans ISDg  Bacteria  decreased coverage  0.0000000272816  n/a   
 
 
-
 
NC_008532  STER_1605  pyruvate-formate lyase activating enzyme  49.79 
 
 
266 aa  238  5e-62  Streptococcus thermophilus LMD-9  Bacteria  normal  n/a   
 
 
-
 
NC_008527  LACR_1999  pyruvate-formate lyase activating enzyme  50.43 
 
 
263 aa  232  4.0000000000000004e-60  Lactococcus lactis subsp. cremoris SK11  Bacteria  normal  0.637211  n/a   
 
 
-
 
NC_008262  CPR_1170  pyruvate formate-lyase activating enzyme  46.29 
 
 
235 aa  228  6e-59  Clostridium perfringens SM101  Bacteria  normal  0.763287  n/a   
 
 
-
 
NC_008261  CPF_1357  pyruvate formate-lyase activating enzyme  46.29 
 
 
235 aa  228  7e-59  Clostridium perfringens ATCC 13124  Bacteria  normal  n/a   
 
 
-
 
NC_004116  SAG1398  pyruvate formate-lyase-activating enzyme  50.42 
 
 
262 aa  227  1e-58  Streptococcus agalactiae 2603V/R  Bacteria  normal  n/a   
 
 
-
 
NC_002976  SERP2365  pyruvate formate-lyase-activating enzyme  49.35 
 
 
251 aa  222  4.9999999999999996e-57  Staphylococcus epidermidis RP62A  Bacteria  normal  n/a   
 
 
-
 
NC_013515  Smon_0297  pyruvate formate-lyase activating enzyme  45.15 
 
 
247 aa  220  9.999999999999999e-57  Streptobacillus moniliformis DSM 12112  Bacteria  n/a    n/a   
 
 
-
 
NC_013521  Sked_16340  pyruvate formate-lyase 1-activating enzyme  42.32 
 
 
287 aa  219  1.9999999999999999e-56  Sanguibacter keddieii DSM 10542  Bacteria  normal  0.243728  normal 
 
 
-
 
NC_011729  PCC7424_2837  pyruvate formate-lyase activating enzyme  44.92 
 
 
255 aa  217  2e-55  Cyanothece sp. PCC 7424  Bacteria  n/a    normal  0.128251 
 
 
-
 
NC_009632  SaurJH1_0217  pyruvate formate-lyase activating enzyme  48.48 
 
 
251 aa  216  2e-55  Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  n/a   
 
 
-
 
NC_009487  SaurJH9_0211  pyruvate formate-lyase activating enzyme  48.48 
 
 
251 aa  216  2e-55  Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  n/a   
 
 
-
 
NC_009253  Dred_0038  pyruvate formate-lyase activating enzyme  44.49 
 
 
229 aa  216  2.9999999999999998e-55  Desulfotomaculum reducens MI-1  Bacteria  normal  n/a   
 
 
-
 
NC_013517  Sterm_2719  pyruvate formate-lyase activating enzyme  45.64 
 
 
241 aa  213  1.9999999999999998e-54  Sebaldella termitidis ATCC 33386  Bacteria  normal  n/a   
 
 
-
 
NC_010655  Amuc_1542  pyruvate formate-lyase activating enzyme  41.18 
 
 
259 aa  209  3e-53  Akkermansia muciniphila ATCC BAA-835  Bacteria  hitchhiker  0.00863407  normal 
 
 
-
 
NC_013721  HMPREF0424_0885  pyruvate formate-lyase 1-activating enzyme  42.06 
 
 
293 aa  204  9e-52  Gardnerella vaginalis 409-05  Bacteria  n/a    normal 
 
 
-
 
NC_010816  BLD_0692  pyruvate-formate lyase-activating enzyme  40.95 
 
 
293 aa  200  1.9999999999999998e-50  Bifidobacterium longum DJO10A  Bacteria  normal  0.104164  n/a   
 
 
-
 
NC_008346  Swol_1049  pyruvate formate lyase activating enzyme  39.41 
 
 
246 aa  197  1.0000000000000001e-49  Syntrophomonas wolfei subsp. wolfei str. Goettingen  Bacteria  normal  n/a   
 
 
-
 
NC_007298  Daro_2097  radical SAM family protein  43.16 
 
 
264 aa  196  2.0000000000000003e-49  Dechloromonas aromatica RCB  Bacteria  normal  normal 
 
 
-
 
NC_013093  Amir_2417  pyruvate formate-lyase activating enzyme  42.79 
 
 
281 aa  197  2.0000000000000003e-49  Actinosynnema mirum DSM 43827  Bacteria  hitchhiker  0.000000163232  n/a   
 
 
-
 
NC_007925  RPC_1081  pyruvate formate-lyase activating  42.11 
 
 
267 aa  195  7e-49  Rhodopseudomonas palustris BisB18  Bacteria  normal  0.257983  normal 
 
 
-
 
NC_007925  RPC_2981  pyruvate formate-lyase activating  42.11 
 
 
267 aa  194  8.000000000000001e-49  Rhodopseudomonas palustris BisB18  Bacteria  normal  0.743712  normal  0.290746 
 
 
-
 
NC_014151  Cfla_1722  pyruvate formate-lyase activating enzyme  38.53 
 
 
293 aa  194  8.000000000000001e-49  Cellulomonas flavigena DSM 20109  Bacteria  normal  0.461343  normal  0.162758 
 
 
-
 
NC_007964  Nham_0890  pyruvate formate-lyase activating  37.08 
 
 
275 aa  192  4e-48  Nitrobacter hamburgensis X14  Bacteria  normal  0.999298  n/a   
 
 
-
 
NC_013530  Xcel_1894  pyruvate formate-lyase activating enzyme  37.8 
 
 
334 aa  190  1e-47  Xylanimonas cellulosilytica DSM 15894  Bacteria  normal  0.703525  n/a   
 
 
-
 
NC_007643  Rru_A2999  radical SAM family protein  39.66 
 
 
265 aa  189  2.9999999999999997e-47  Rhodospirillum rubrum ATCC 11170  Bacteria  normal  n/a   
 
 
-
 
NC_013203  Apar_0654  pyruvate formate-lyase activating enzyme  43.3 
 
 
260 aa  182  4.0000000000000006e-45  Atopobium parvulum DSM 20469  Bacteria  hitchhiker  0.00347583  normal 
 
 
-
 
NC_013174  Jden_1397  pyruvate formate-lyase activating enzyme  38.26 
 
 
310 aa  162  7e-39  Jonesia denitrificans DSM 20603  Bacteria  normal  normal  0.559642 
 
 
-
 
NC_013235  Namu_3207  pyruvate formate-lyase activating enzyme  37.55 
 
 
267 aa  160  1e-38  Nakamurella multipartita DSM 44233  Bacteria  decreased coverage  0.000377553  hitchhiker  0.000844358 
 
 
-
 
NC_010001  Cphy_1175  glycyl-radical activating family protein  34.39 
 
 
263 aa  155  7e-37  Clostridium phytofermentans ISDg  Bacteria  normal  0.0579151  n/a   
 
 
-
 
NC_009253  Dred_2966  glycyl-radical activating family protein  31.67 
 
 
297 aa  145  5e-34  Desulfotomaculum reducens MI-1  Bacteria  normal  n/a   
 
 
-
 
NC_007498  Pcar_1396  glycerol dehydratase activating enzyme  35.53 
 
 
322 aa  140  1.9999999999999998e-32  Pelobacter carbinolicus DSM 2380  Bacteria  normal  0.214688  n/a   
 
 
-
 
NC_013517  Sterm_1938  glycyl-radical enzyme activating protein family  31.5 
 
 
273 aa  135  4e-31  Sebaldella termitidis ATCC 33386  Bacteria  normal  0.239617  n/a   
 
 
-
 
NC_009356  OSTLU_36094  predicted protein  33.98 
 
 
324 aa  135  5e-31  Ostreococcus lucimarinus CCE9901  Eukaryota  normal  n/a   
 
 
-
 
NC_004116  SAG0325  pyruvate formate-lyase-activating enzyme  31.08 
 
 
258 aa  127  2.0000000000000002e-28  Streptococcus agalactiae 2603V/R  Bacteria  normal  0.719518  n/a   
 
 
-
 
NC_007519  Dde_3054  radical-activating enzyme  30.69 
 
 
302 aa  125  5e-28  Desulfovibrio desulfuricans subsp. desulfuricans str. G20  Bacteria  normal  0.969131  n/a   
 
 
-
 
NC_013517  Sterm_3704  glycyl-radical enzyme activating protein family  31.36 
 
 
304 aa  125  5e-28  Sebaldella termitidis ATCC 33386  Bacteria  normal  n/a   
 
 
-
 
NC_013421  Pecwa_4091  glycyl-radical enzyme activating protein family  32.16 
 
 
305 aa  125  6e-28  Pectobacterium wasabiae WPP163  Bacteria  normal  n/a   
 
 
-
 
NC_009438  Sputcn32_0207  glycyl-radical activating family protein  31.37 
 
 
306 aa  125  6e-28  Shewanella putrefaciens CN-32  Bacteria  normal  n/a   
 
 
-
 
NC_002939  GSU2102  pyruvate formate-lyase-activating enzyme, putative  28.16 
 
 
298 aa  125  9e-28  Geobacter sulfurreducens PCA  Bacteria  normal  0.510382  n/a   
 
 
-
 
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