More than 300 homologs were found in PanDaTox collection
for query gene Tmel_0460 on replicon NC_009616
Organism: Thermosipho melanesiensis BI429



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_009616  Tmel_0460  response regulator receiver protein  100 
 
 
119 aa  237  4e-62  Thermosipho melanesiensis BI429  Bacteria  normal  0.903697  n/a   
 
 
-
 
NC_009718  Fnod_1426  response regulator receiver protein  76.72 
 
 
118 aa  191  3e-48  Fervidobacterium nodosum Rt17-B1  Bacteria  normal  n/a   
 
 
-
 
NC_009486  Tpet_1423  response regulator receiver protein  66.09 
 
 
116 aa  147  4e-35  Thermotoga petrophila RKU-1  Bacteria  normal  n/a   
 
 
-
 
NC_010483  TRQ2_1469  response regulator receiver protein  66.09 
 
 
116 aa  147  4e-35  Thermotoga sp. RQ2  Bacteria  normal  n/a   
 
 
-
 
NC_010003  Pmob_1627  response regulator receiver protein  59.48 
 
 
119 aa  141  4e-33  Petrotoga mobilis SJ95  Bacteria  normal  n/a   
 
 
-
 
NC_008609  Ppro_0029  response regulator receiver protein  46.02 
 
 
126 aa  110  5e-24  Pelobacter propionicus DSM 2379  Bacteria  normal  n/a   
 
 
-
 
NC_007498  Pcar_2959  two component signal transduction response regulator  49.12 
 
 
128 aa  108  2.0000000000000002e-23  Pelobacter carbinolicus DSM 2380  Bacteria  normal  0.888929  n/a   
 
 
-
 
NC_014150  Bmur_0458  response regulator receiver protein  44.17 
 
 
120 aa  108  2.0000000000000002e-23  Brachyspira murdochii DSM 12563  Bacteria  hitchhiker  0.000275929  n/a   
 
 
-
 
NC_010814  Glov_0406  response regulator receiver protein  44.25 
 
 
126 aa  105  3e-22  Geobacter lovleyi SZ  Bacteria  normal  n/a   
 
 
-
 
NC_011146  Gbem_3403  response regulator receiver protein  44.25 
 
 
124 aa  103  6e-22  Geobacter bemidjiensis Bem  Bacteria  normal  0.809384  n/a   
 
 
-
 
NC_012918  GM21_3466  response regulator receiver protein  43.36 
 
 
125 aa  101  3e-21  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_009483  Gura_0854  response regulator receiver protein  42.98 
 
 
124 aa  100  7e-21  Geobacter uraniireducens Rf4  Bacteria  normal  n/a   
 
 
-
 
NC_008554  Sfum_0187  response regulator receiver protein  50.45 
 
 
122 aa  98.6  2e-20  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  0.283319  normal 
 
 
-
 
NC_002939  GSU3253  response regulator  40.71 
 
 
123 aa  93.2  1e-18  Geobacter sulfurreducens PCA  Bacteria  normal  n/a   
 
 
-
 
NC_010718  Nther_0252  response regulator receiver protein  48.78 
 
 
239 aa  91.3  4e-18  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  normal  0.114255 
 
 
-
 
NC_011831  Cagg_2217  two component transcriptional regulator, winged helix family  39.13 
 
 
276 aa  90.9  6e-18  Chloroflexus aggregans DSM 9485  Bacteria  hitchhiker  0.00294817  normal 
 
 
-
 
NC_007517  Gmet_3179  response regulator receiver domain-containing protein  41.59 
 
 
120 aa  90.5  7e-18  Geobacter metallireducens GS-15  Bacteria  normal  normal  0.164981 
 
 
-
 
NC_010814  Glov_2786  two component, sigma54 specific, transcriptional regulator, Fis family  39.83 
 
 
480 aa  89  2e-17  Geobacter lovleyi SZ  Bacteria  normal  0.543097  n/a   
 
 
-
 
NC_008609  Ppro_0435  response regulator receiver protein  40.68 
 
 
124 aa  89  2e-17  Pelobacter propionicus DSM 2379  Bacteria  hitchhiker  0.00876892  n/a   
 
 
-
 
NC_002939  GSU1003  nitrogen regulation protein NR(I)  40.35 
 
 
481 aa  87.4  5e-17  Geobacter sulfurreducens PCA  Bacteria  normal  0.158383  n/a   
 
 
-
 
NC_007519  Dde_3609  response regulator receiver domain-containing protein  44.07 
 
 
122 aa  86.3  1e-16  Desulfovibrio desulfuricans subsp. desulfuricans str. G20  Bacteria  normal  n/a   
 
 
-
 
NC_007517  Gmet_2563  two component, sigma54 specific, Fis family transcriptional regulator  38.6 
 
 
480 aa  85.5  2e-16  Geobacter metallireducens GS-15  Bacteria  normal  hitchhiker  0.00247378 
 
 
-
 
NC_009483  Gura_0916  two component, sigma-54 specific, Fis family transcriptional regulator  38.14 
 
 
480 aa  85.5  2e-16  Geobacter uraniireducens Rf4  Bacteria  normal  n/a   
 
 
-
 
NC_009455  DehaBAV1_1106  response regulator receiver protein  48.75 
 
 
180 aa  85.1  3e-16  Dehalococcoides sp. BAV1  Bacteria  normal  0.0674112  n/a   
 
 
-
 
NC_002936  DET1294  DNA-binding response regulator  45.78 
 
 
180 aa  84.7  4e-16  Dehalococcoides ethenogenes 195  Bacteria  unclonable  0.00000125664  n/a   
 
 
-
 
NC_013552  DhcVS_1078  DNA-binding response regulator  46.99 
 
 
180 aa  84.7  4e-16  Dehalococcoides sp. VS  Bacteria  unclonable  0.00000000000063084  n/a   
 
 
-
 
NC_009943  Dole_1364  two component, sigma54 specific, Fis family transcriptional regulator  35.96 
 
 
485 aa  83.6  8e-16  Desulfococcus oleovorans Hxd3  Bacteria  normal  n/a   
 
 
-
 
NC_011769  DvMF_2332  response regulator receiver protein  43.97 
 
 
122 aa  83.6  9e-16  Desulfovibrio vulgaris str. 'Miyazaki F'  Bacteria  n/a    normal 
 
 
-
 
NC_008609  Ppro_3079  two component, sigma54 specific, Fis family transcriptional regulator  39.81 
 
 
480 aa  83.6  9e-16  Pelobacter propionicus DSM 2379  Bacteria  hitchhiker  0.00177638  n/a   
 
 
-
 
NC_003909  BCE_1413  DNA-binding response regulator  45.05 
 
 
223 aa  82  0.000000000000003  Bacillus cereus ATCC 10987  Bacteria  normal  n/a   
 
 
-
 
NC_011830  Dhaf_3739  two component transcriptional regulator, winged helix family  45.28 
 
 
230 aa  82  0.000000000000003  Desulfitobacterium hafniense DCB-2  Bacteria  decreased coverage  0.0000000000466515  n/a   
 
 
-
 
NC_011658  BCAH187_A1453  DNA-binding response regulator  45.05 
 
 
223 aa  82  0.000000000000003  Bacillus cereus AH187  Bacteria  normal  n/a   
 
 
-
 
NC_005945  BAS1213  DNA-binding response regulator  45.05 
 
 
223 aa  81.3  0.000000000000004  Bacillus anthracis str. Sterne  Bacteria  normal  0.203275  n/a   
 
 
-
 
NC_005957  BT9727_1191  response regulator  45.05 
 
 
223 aa  81.3  0.000000000000004  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  n/a   
 
 
-
 
NC_006274  BCZK1193  response regulator  45.05 
 
 
223 aa  81.3  0.000000000000004  Bacillus cereus E33L  Bacteria  normal  n/a   
 
 
-
 
NC_007530  GBAA_1312  DNA-binding response regulator  45.05 
 
 
223 aa  81.3  0.000000000000004  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  n/a   
 
 
-
 
NC_011773  BCAH820_1389  DNA-binding response regulator  45.05 
 
 
223 aa  81.3  0.000000000000004  Bacillus cereus AH820  Bacteria  n/a    normal 
 
 
-
 
NC_012918  GM21_1525  response regulator receiver modulated diguanylate cyclase  40.43 
 
 
316 aa  80.9  0.000000000000005  Geobacter sp. M21  Bacteria  n/a    hitchhiker  2.15223e-23 
 
 
-
 
NC_013173  Dbac_1110  response regulator receiver protein  38.46 
 
 
117 aa  80.9  0.000000000000006  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  n/a   
 
 
-
 
NC_011059  Paes_0769  two component transcriptional regulator, winged helix family  40.5 
 
 
236 aa  80.5  0.000000000000006  Prosthecochloris aestuarii DSM 271  Bacteria  normal  normal 
 
 
-
 
NC_004116  SAG0616  DNA-binding response regulator VncR  46.09 
 
 
217 aa  80.5  0.000000000000007  Streptococcus agalactiae 2603V/R  Bacteria  normal  n/a   
 
 
-
 
NC_013205  Aaci_2784  response regulator receiver protein  37.84 
 
 
125 aa  80.5  0.000000000000007  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  0.0945133  n/a   
 
 
-
 
NC_011146  Gbem_2715  response regulator receiver modulated diguanylate cyclase  40.43 
 
 
314 aa  80.5  0.000000000000007  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_009674  Bcer98_1200  two component transcriptional regulator  45.19 
 
 
238 aa  79.7  0.00000000000001  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  n/a   
 
 
-
 
NC_011772  BCG9842_B3993  DNA-binding response regulator  44.14 
 
 
223 aa  80.1  0.00000000000001  Bacillus cereus G9842  Bacteria  normal  normal  0.910988 
 
 
-
 
NC_011725  BCB4264_A1351  DNA-binding response regulator  44.14 
 
 
223 aa  80.1  0.00000000000001  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_013205  Aaci_1728  two component transcriptional regulator, winged helix family  40.54 
 
 
233 aa  79.7  0.00000000000001  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  n/a   
 
 
-
 
NC_011831  Cagg_2019  GAF sensor hybrid histidine kinase  31.67 
 
 
1016 aa  79.3  0.00000000000002  Chloroflexus aggregans DSM 9485  Bacteria  normal  0.25506  normal 
 
 
-
 
NC_009483  Gura_0495  two component, sigma-54 specific, Fis family transcriptional regulator  39.32 
 
 
456 aa  79  0.00000000000002  Geobacter uraniireducens Rf4  Bacteria  normal  n/a   
 
 
-
 
NC_011830  Dhaf_2159  two component transcriptional regulator, winged helix family  43.1 
 
 
227 aa  79  0.00000000000002  Desulfitobacterium hafniense DCB-2  Bacteria  hitchhiker  0.00177162  n/a   
 
 
-
 
NC_002939  GSU1658  response regulator/GGDEF domain-containing protein  34.51 
 
 
458 aa  78.2  0.00000000000003  Geobacter sulfurreducens PCA  Bacteria  normal  0.939598  n/a   
 
 
-
 
NC_013223  Dret_2392  two component, sigma54 specific, transcriptional regulator, Fis family  45 
 
 
458 aa  78.2  0.00000000000003  Desulfohalobium retbaense DSM 5692  Bacteria  normal  0.0321511  normal 
 
 
-
 
NC_008262  CPR_2077  vncR, response regulator  44.35 
 
 
217 aa  78.2  0.00000000000003  Clostridium perfringens SM101  Bacteria  decreased coverage  0.00119329  n/a   
 
 
-
 
NC_009487  SaurJH9_1476  two component transcriptional regulator  40 
 
 
219 aa  78.6  0.00000000000003  Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  n/a   
 
 
-
 
NC_009632  SaurJH1_1505  response regulator receiver  40 
 
 
219 aa  78.6  0.00000000000003  Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  0.404603  n/a   
 
 
-
 
NC_010814  Glov_3210  response regulator receiver modulated diguanylate cyclase with PAS/PAC sensor  41.74 
 
 
425 aa  78.2  0.00000000000003  Geobacter lovleyi SZ  Bacteria  normal  0.141244  n/a   
 
 
-
 
NC_012918  GM21_1405  two component, sigma54 specific, transcriptional regulator, Fis family  35.59 
 
 
478 aa  78.2  0.00000000000003  Geobacter sp. M21  Bacteria  n/a    hitchhiker  0.0000117702 
 
 
-
 
NC_010184  BcerKBAB4_1215  two component transcriptional regulator  44.14 
 
 
223 aa  78.6  0.00000000000003  Bacillus weihenstephanensis KBAB4  Bacteria  normal  0.533573  n/a   
 
 
-
 
NC_011146  Gbem_2805  two component, sigma54 specific, transcriptional regulator, Fis family  35.59 
 
 
478 aa  78.2  0.00000000000004  Geobacter bemidjiensis Bem  Bacteria  normal  0.228775  n/a   
 
 
-
 
NC_011830  Dhaf_2193  two component transcriptional regulator, winged helix family  43.7 
 
 
237 aa  78.2  0.00000000000004  Desulfitobacterium hafniense DCB-2  Bacteria  normal  0.0620475  n/a   
 
 
-
 
NC_011369  Rleg2_3569  response regulator receiver protein  37.07 
 
 
119 aa  77.8  0.00000000000004  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  normal  0.146165 
 
 
-
 
NC_008751  Dvul_2829  response regulator receiver protein  42.24 
 
 
126 aa  77.4  0.00000000000006  Desulfovibrio vulgaris DP4  Bacteria  normal  0.597834  normal 
 
 
-
 
NC_010814  Glov_3603  response regulator receiver protein  38.66 
 
 
131 aa  77.4  0.00000000000006  Geobacter lovleyi SZ  Bacteria  normal  0.656399  n/a   
 
 
-
 
NC_009718  Fnod_0785  two component transcriptional regulator  40 
 
 
229 aa  77.4  0.00000000000007  Fervidobacterium nodosum Rt17-B1  Bacteria  normal  0.0635827  n/a   
 
 
-
 
NC_012793  GWCH70_3334  response regulator receiver protein  33.63 
 
 
120 aa  77  0.00000000000008  Geobacillus sp. WCH70  Bacteria  normal  n/a   
 
 
-
 
NC_002939  GSU1117  response regulator  35.9 
 
 
127 aa  76.3  0.0000000000001  Geobacter sulfurreducens PCA  Bacteria  normal  n/a   
 
 
-
 
NC_009483  Gura_1986  two component heavy metal response transcriptional regulator  36.21 
 
 
223 aa  76.6  0.0000000000001  Geobacter uraniireducens Rf4  Bacteria  normal  0.0566795  n/a   
 
 
-
 
NC_009943  Dole_2810  response regulator receiver protein  35.66 
 
 
127 aa  76.6  0.0000000000001  Desulfococcus oleovorans Hxd3  Bacteria  normal  0.0130618  n/a   
 
 
-
 
NC_007517  Gmet_2710  CheA signal transduction histidine kinase  38.84 
 
 
777 aa  76.6  0.0000000000001  Geobacter metallireducens GS-15  Bacteria  normal  normal 
 
 
-
 
NC_008527  LACR_1701  DNA-binding response regulator  38.74 
 
 
230 aa  76.6  0.0000000000001  Lactococcus lactis subsp. cremoris SK11  Bacteria  hitchhiker  0.00672994  n/a   
 
 
-
 
NC_012850  Rleg_3862  response regulator receiver protein  37.07 
 
 
119 aa  76.6  0.0000000000001  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  0.762525  normal  0.105944 
 
 
-
 
NC_002939  GSU1495  sigma-54 dependent DNA-binding response regulator  36.45 
 
 
458 aa  75.9  0.0000000000002  Geobacter sulfurreducens PCA  Bacteria  normal  0.301103  n/a   
 
 
-
 
NC_009253  Dred_2981  two component transcriptional regulator  38.33 
 
 
229 aa  75.9  0.0000000000002  Desulfotomaculum reducens MI-1  Bacteria  unclonable  0.0000000201285  n/a   
 
 
-
 
NC_011146  Gbem_1342  two component transcriptional regulator, winged helix family  37.61 
 
 
234 aa  75.5  0.0000000000002  Geobacter bemidjiensis Bem  Bacteria  normal  0.0144629  n/a   
 
 
-
 
NC_007643  Rru_A2820  multi-sensor hybrid histidine kinase / cell cycle control histidine kinase CckA  34.75 
 
 
829 aa  75.5  0.0000000000002  Rhodospirillum rubrum ATCC 11170  Bacteria  normal  n/a   
 
 
-
 
NC_007948  Bpro_1956  two component transcriptional regulator  36.45 
 
 
223 aa  75.9  0.0000000000002  Polaromonas sp. JS666  Bacteria  decreased coverage  0.0000121146  normal  0.806146 
 
 
-
 
NC_013411  GYMC61_3444  response regulator receiver protein  33.62 
 
 
120 aa  75.5  0.0000000000002  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_009674  Bcer98_1021  two component transcriptional regulator  43.24 
 
 
223 aa  75.9  0.0000000000002  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  n/a   
 
 
-
 
NC_012918  GM21_2942  two component transcriptional regulator, winged helix family  36.7 
 
 
234 aa  75.1  0.0000000000003  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_009441  Fjoh_4970  two component transcriptional regulator  35.14 
 
 
228 aa  75.1  0.0000000000003  Flavobacterium johnsoniae UW101  Bacteria  normal  0.375881  n/a   
 
 
-
 
NC_010571  Oter_2939  response regulator receiver protein  48.15 
 
 
125 aa  75.1  0.0000000000003  Opitutus terrae PB90-1  Bacteria  normal  0.302842  normal 
 
 
-
 
NC_007517  Gmet_2679  response regulator receiver domain-containing protein  34.75 
 
 
129 aa  75.1  0.0000000000003  Geobacter metallireducens GS-15  Bacteria  normal  0.380915  normal  0.27601 
 
 
-
 
NC_007650  BTH_II1189  response regulator  34.48 
 
 
229 aa  75.1  0.0000000000003  Burkholderia thailandensis E264  Bacteria  normal  n/a   
 
 
-
 
NC_014230  CA2559_09498  two-component system, transcriptional regulatory protein  39.42 
 
 
236 aa  75.1  0.0000000000003  Croceibacter atlanticus HTCC2559  Bacteria  normal  n/a   
 
 
-
 
NC_013216  Dtox_3783  histidine kinase  42.57 
 
 
544 aa  75.1  0.0000000000003  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  0.401083  normal 
 
 
-
 
NC_008528  OEOE_1773  DNA-binding response regulator  33.91 
 
 
224 aa  75.1  0.0000000000003  Oenococcus oeni PSU-1  Bacteria  normal  n/a   
 
 
-
 
NC_010184  BcerKBAB4_1399  two component transcriptional regulator  43.27 
 
 
238 aa  75.1  0.0000000000003  Bacillus weihenstephanensis KBAB4  Bacteria  normal  0.129694  n/a   
 
 
-
 
NC_011899  Hore_10620  response regulator receiver protein  38.98 
 
 
122 aa  74.7  0.0000000000004  Halothermothrix orenii H 168  Bacteria  hitchhiker  0.00212992  n/a   
 
 
-
 
NC_009675  Anae109_1530  response regulator receiver protein  34.45 
 
 
127 aa  74.7  0.0000000000004  Anaeromyxobacter sp. Fw109-5  Bacteria  normal  0.754323  normal 
 
 
-
 
NC_013061  Phep_1345  response regulator receiver  38.32 
 
 
227 aa  74.7  0.0000000000004  Pedobacter heparinus DSM 2366  Bacteria  normal  normal  0.71904 
 
 
-
 
NC_008532  STER_0354  DNA-binding response regulator  38.89 
 
 
229 aa  74.7  0.0000000000004  Streptococcus thermophilus LMD-9  Bacteria  unclonable  0.00000041064  n/a   
 
 
-
 
NC_008554  Sfum_0821  response regulator receiver modulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase  36.7 
 
 
1139 aa  74.7  0.0000000000004  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  normal  0.187038 
 
 
-
 
NC_013730  Slin_3615  putative two component, sigma54 specific, transcriptional regulator, Fis family  33.91 
 
 
383 aa  74.3  0.0000000000005  Spirosoma linguale DSM 74  Bacteria  normal  normal  0.176603 
 
 
-
 
NC_013501  Rmar_0987  two component transcriptional regulator, winged helix family  38.32 
 
 
233 aa  74.3  0.0000000000005  Rhodothermus marinus DSM 4252  Bacteria  normal  0.195539  n/a   
 
 
-
 
NC_007760  Adeh_2009  two component, sigma54 specific, Fis family transcriptional regulator  35.59 
 
 
463 aa  74.3  0.0000000000005  Anaeromyxobacter dehalogenans 2CP-C  Bacteria  normal  n/a   
 
 
-
 
NC_013522  Taci_0717  two component transcriptional regulator, winged helix family  37.38 
 
 
226 aa  74.3  0.0000000000005  Thermanaerovibrio acidaminovorans DSM 6589  Bacteria  hitchhiker  0.000154116  n/a   
 
 
-
 
NC_011769  DvMF_0215  two component, sigma54 specific, transcriptional regulator, Fis family  35.09 
 
 
528 aa  74.7  0.0000000000005  Desulfovibrio vulgaris str. 'Miyazaki F'  Bacteria  n/a    normal  0.0571306 
 
 
-
 
NC_013595  Sros_8872  response regulator receiver protein  37.39 
 
 
234 aa  73.9  0.0000000000007  Streptosporangium roseum DSM 43021  Bacteria  normal  0.347509  normal 
 
 
-
 
NC_009455  DehaBAV1_0241  response regulator receiver protein  33.88 
 
 
123 aa  73.9  0.0000000000007  Dehalococcoides sp. BAV1  Bacteria  normal  n/a   
 
 
-
 
NC_009523  RoseRS_0805  two component transcriptional regulator  39.13 
 
 
229 aa  73.9  0.0000000000007  Roseiflexus sp. RS-1  Bacteria  normal  normal 
 
 
-
 
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