More than 300 homologs were found in PanDaTox collection
for query gene Tcur_1694 on replicon NC_013510
Organism: Thermomonospora curvata DSM 43183



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_013510  Tcur_1694  two component transcriptional regulator, winged helix family  100 
 
 
217 aa  426  1e-118  Thermomonospora curvata DSM 43183  Bacteria  hitchhiker  0.00296965  n/a   
 
 
-
 
NC_014165  Tbis_2298  winged helix family two component transcriptional regulator  82.03 
 
 
217 aa  348  3e-95  Thermobispora bispora DSM 43833  Bacteria  normal  normal  0.359979 
 
 
-
 
NC_007333  Tfu_1941  response regulator receiver  76.96 
 
 
217 aa  338  5e-92  Thermobifida fusca YX  Bacteria  normal  n/a   
 
 
-
 
NC_013595  Sros_6773  response regulator receiver protein  79.53 
 
 
215 aa  335  2.9999999999999997e-91  Streptosporangium roseum DSM 43021  Bacteria  normal  normal 
 
 
-
 
NC_014210  Ndas_2885  two component transcriptional regulator, winged helix family  75.58 
 
 
217 aa  324  6e-88  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  normal  0.56822 
 
 
-
 
NC_013131  Caci_1627  two component transcriptional regulator, winged helix family  75.58 
 
 
218 aa  322  2e-87  Catenulispora acidiphila DSM 44928  Bacteria  normal  normal  0.393195 
 
 
-
 
NC_013595  Sros_0304  response regulator receiver protein  71.89 
 
 
218 aa  301  4.0000000000000003e-81  Streptosporangium roseum DSM 43021  Bacteria  normal  0.818258  normal 
 
 
-
 
NC_013947  Snas_5939  two component transcriptional regulator, winged helix family  68.66 
 
 
218 aa  296  1e-79  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  normal 
 
 
-
 
NC_013131  Caci_1032  two component transcriptional regulator, winged helix family  70.05 
 
 
218 aa  293  1e-78  Catenulispora acidiphila DSM 44928  Bacteria  normal  normal  0.015145 
 
 
-
 
NC_008726  Mvan_3839  two component transcriptional regulator  70.89 
 
 
214 aa  288  4e-77  Mycobacterium vanbaalenii PYR-1  Bacteria  normal  normal 
 
 
-
 
NC_009921  Franean1_6946  two component transcriptional regulator  67.28 
 
 
219 aa  288  6e-77  Frankia sp. EAN1pec  Bacteria  normal  normal  0.383627 
 
 
-
 
NC_013521  Sked_25330  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  66.2 
 
 
214 aa  282  3.0000000000000004e-75  Sanguibacter keddieii DSM 10542  Bacteria  normal  normal 
 
 
-
 
NC_013131  Caci_8629  two component transcriptional regulator, winged helix family  66.36 
 
 
218 aa  266  1e-70  Catenulispora acidiphila DSM 44928  Bacteria  normal  0.0375098  normal 
 
 
-
 
NC_013595  Sros_0839  response regulator receiver protein  66.82 
 
 
217 aa  266  2e-70  Streptosporangium roseum DSM 43021  Bacteria  normal  normal 
 
 
-
 
NC_009953  Sare_1458  two component transcriptional regulator  64.52 
 
 
222 aa  265  2.9999999999999995e-70  Salinispora arenicola CNS-205  Bacteria  normal  hitchhiker  0.00630531 
 
 
-
 
NC_013159  Svir_24140  response regulator with CheY-like receiver domain protein and winged-helix DNA-binding domain protein  66.82 
 
 
231 aa  265  2.9999999999999995e-70  Saccharomonospora viridis DSM 43017  Bacteria  decreased coverage  0.00201668  decreased coverage  0.0036779 
 
 
-
 
NC_013947  Snas_0152  two component transcriptional regulator, winged helix family  63.59 
 
 
218 aa  264  8.999999999999999e-70  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  normal  0.541846 
 
 
-
 
NC_009380  Strop_1496  response regulator receiver  64.52 
 
 
222 aa  264  1e-69  Salinispora tropica CNB-440  Bacteria  normal  0.23196  normal  0.62159 
 
 
-
 
NC_013947  Snas_4521  two component transcriptional regulator, winged helix family  61.75 
 
 
223 aa  261  4.999999999999999e-69  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  normal  0.315032 
 
 
-
 
NC_014211  Ndas_4944  two component transcriptional regulator, winged helix family  60.83 
 
 
224 aa  253  1.0000000000000001e-66  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  normal 
 
 
-
 
NC_013235  Namu_3750  two component transcriptional regulator, winged helix family  63.13 
 
 
220 aa  250  1e-65  Nakamurella multipartita DSM 44233  Bacteria  normal  0.169526  normal  0.108117 
 
 
-
 
NC_013131  Caci_6645  two component transcriptional regulator, winged helix family  60.83 
 
 
217 aa  248  7e-65  Catenulispora acidiphila DSM 44928  Bacteria  normal  normal  0.129361 
 
 
-
 
NC_009921  Franean1_0082  two component transcriptional regulator  61.29 
 
 
219 aa  244  6e-64  Frankia sp. EAN1pec  Bacteria  normal  normal 
 
 
-
 
NC_013093  Amir_1526  two component transcriptional regulator, winged helix family  65.44 
 
 
225 aa  243  1.9999999999999999e-63  Actinosynnema mirum DSM 43827  Bacteria  normal  n/a   
 
 
-
 
NC_014210  Ndas_4784  two component transcriptional regulator, winged helix family  59.17 
 
 
218 aa  242  3e-63  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  0.0755771  normal 
 
 
-
 
NC_013739  Cwoe_0520  two component transcriptional regulator, winged helix family  58.72 
 
 
226 aa  241  5e-63  Conexibacter woesei DSM 14684  Bacteria  normal  0.896215  normal 
 
 
-
 
NC_013131  Caci_5788  two component transcriptional regulator, winged helix family  61.29 
 
 
235 aa  234  7e-61  Catenulispora acidiphila DSM 44928  Bacteria  normal  0.767422  normal 
 
 
-
 
NC_013947  Snas_6028  two component transcriptional regulator, winged helix family  61.29 
 
 
227 aa  231  5e-60  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  normal  0.497989 
 
 
-
 
NC_013595  Sros_5651  response regulator receiver protein  57.28 
 
 
222 aa  231  7.000000000000001e-60  Streptosporangium roseum DSM 43021  Bacteria  normal  0.205762  normal 
 
 
-
 
NC_013595  Sros_4756  response regulator receiver protein  59.91 
 
 
231 aa  229  2e-59  Streptosporangium roseum DSM 43021  Bacteria  normal  0.666575  normal  0.223314 
 
 
-
 
NC_014158  Tpau_0520  two component transcriptional regulator, winged helix family  59.45 
 
 
224 aa  228  5e-59  Tsukamurella paurometabola DSM 20162  Bacteria  normal  n/a   
 
 
-
 
NC_009921  Franean1_7133  two component transcriptional regulator  58.99 
 
 
243 aa  227  1e-58  Frankia sp. EAN1pec  Bacteria  normal  0.0709918  normal 
 
 
-
 
NC_013521  Sked_26840  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  57.6 
 
 
227 aa  226  2e-58  Sanguibacter keddieii DSM 10542  Bacteria  normal  normal  0.871857 
 
 
-
 
NC_013739  Cwoe_3363  two component transcriptional regulator, winged helix family  55.81 
 
 
218 aa  226  2e-58  Conexibacter woesei DSM 14684  Bacteria  normal  normal  0.0369165 
 
 
-
 
NC_013093  Amir_4514  two component transcriptional regulator, winged helix family  61.19 
 
 
222 aa  224  7e-58  Actinosynnema mirum DSM 43827  Bacteria  normal  0.0331921  n/a   
 
 
-
 
NC_013530  Xcel_1424  two component transcriptional regulator, winged helix family  58.53 
 
 
227 aa  223  2e-57  Xylanimonas cellulosilytica DSM 15894  Bacteria  normal  0.962771  n/a   
 
 
-
 
NC_013739  Cwoe_1412  two component transcriptional regulator, winged helix family  57.48 
 
 
228 aa  218  5e-56  Conexibacter woesei DSM 14684  Bacteria  normal  normal  0.789808 
 
 
-
 
NC_007777  Francci3_2444  two component transcriptional regulator  58.99 
 
 
221 aa  218  7.999999999999999e-56  Frankia sp. CcI3  Bacteria  normal  0.237692  normal 
 
 
-
 
NC_013131  Caci_0470  two component transcriptional regulator, winged helix family  59.07 
 
 
234 aa  215  2.9999999999999998e-55  Catenulispora acidiphila DSM 44928  Bacteria  normal  normal 
 
 
-
 
NC_014211  Ndas_5374  two component transcriptional regulator, winged helix family  51.61 
 
 
218 aa  212  3.9999999999999995e-54  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  normal 
 
 
-
 
NC_009523  RoseRS_2625  two component transcriptional regulator  49.77 
 
 
231 aa  200  9.999999999999999e-51  Roseiflexus sp. RS-1  Bacteria  normal  0.983258  normal 
 
 
-
 
NC_011661  Dtur_0537  two component transcriptional regulator, winged helix family  42.34 
 
 
224 aa  185  5e-46  Dictyoglomus turgidum DSM 6724  Bacteria  normal  0.0716782  n/a   
 
 
-
 
NC_009921  Franean1_3859  two component transcriptional regulator  48.42 
 
 
235 aa  181  9.000000000000001e-45  Frankia sp. EAN1pec  Bacteria  normal  0.0389848  normal 
 
 
-
 
NC_011369  Rleg2_0704  two component transcriptional regulator, winged helix family  46.64 
 
 
227 aa  180  2e-44  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  0.205827  normal  0.593451 
 
 
-
 
NC_008699  Noca_1613  response regulator receiver  48.65 
 
 
225 aa  179  2.9999999999999997e-44  Nocardioides sp. JS614  Bacteria  normal  0.97266  n/a   
 
 
-
 
NC_012850  Rleg_0767  two component transcriptional regulator, winged helix family  46.19 
 
 
229 aa  179  4e-44  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  0.870104  normal 
 
 
-
 
NC_014151  Cfla_0861  two component transcriptional regulator, winged helix family  48.17 
 
 
225 aa  177  9e-44  Cellulomonas flavigena DSM 20109  Bacteria  normal  0.156886  normal 
 
 
-
 
NC_013595  Sros_3423  response regulator receiver protein  48.64 
 
 
224 aa  175  4e-43  Streptosporangium roseum DSM 43021  Bacteria  normal  0.699539  normal  0.107362 
 
 
-
 
NC_013947  Snas_2104  two component transcriptional regulator, winged helix family  46.82 
 
 
225 aa  175  5e-43  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  0.302064  normal  0.805943 
 
 
-
 
NC_002947  PP_1438  DNA-binding response regulator CzrR  45.25 
 
 
224 aa  173  9.999999999999999e-43  Pseudomonas putida KT2440  Bacteria  normal  normal 
 
 
-
 
NC_009512  Pput_4283  two component heavy metal response transcriptional regulator  45.25 
 
 
224 aa  173  9.999999999999999e-43  Pseudomonas putida F1  Bacteria  normal  0.0230752  normal 
 
 
-
 
NC_011831  Cagg_3502  two component transcriptional regulator, winged helix family  48.42 
 
 
232 aa  173  1.9999999999999998e-42  Chloroflexus aggregans DSM 9485  Bacteria  normal  normal 
 
 
-
 
NC_009767  Rcas_2599  two component transcriptional regulator  48.42 
 
 
232 aa  173  1.9999999999999998e-42  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.268704  normal 
 
 
-
 
NC_007492  Pfl01_3624  two component heavy metal response transcriptional regulator  44.34 
 
 
224 aa  171  9e-42  Pseudomonas fluorescens Pf0-1  Bacteria  normal  normal 
 
 
-
 
NC_010322  PputGB1_4369  two component heavy metal response transcriptional regulator  44.8 
 
 
224 aa  171  1e-41  Pseudomonas putida GB-1  Bacteria  normal  normal  0.0732935 
 
 
-
 
NC_010003  Pmob_0851  two component transcriptional regulator  44.29 
 
 
222 aa  171  1e-41  Petrotoga mobilis SJ95  Bacteria  normal  n/a   
 
 
-
 
NC_008537  Arth_4535  two component transcriptional regulator  44.55 
 
 
227 aa  170  1e-41  Arthrobacter sp. FB24  Bacteria  normal  n/a   
 
 
-
 
NC_013730  Slin_2929  two component transcriptional regulator, winged helix family  45.05 
 
 
230 aa  170  1e-41  Spirosoma linguale DSM 74  Bacteria  normal  0.0551332  normal 
 
 
-
 
NC_002939  GSU0451  DNA-binding response regulator  43.64 
 
 
224 aa  170  2e-41  Geobacter sulfurreducens PCA  Bacteria  normal  0.313098  n/a   
 
 
-
 
NC_007777  Francci3_2401  two component transcriptional regulator  47.3 
 
 
283 aa  170  2e-41  Frankia sp. CcI3  Bacteria  normal  0.0476592  normal  0.0197415 
 
 
-
 
NC_010831  Cphamn1_0990  two component transcriptional regulator, winged helix family  41.28 
 
 
222 aa  169  3e-41  Chlorobium phaeobacteroides BS1  Bacteria  hitchhiker  0.000957791  decreased coverage  0.0000715536 
 
 
-
 
NC_002947  PP_0047  DNA-binding heavy metal response regulator, putative  43.44 
 
 
224 aa  169  3e-41  Pseudomonas putida KT2440  Bacteria  normal  0.116112  hitchhiker  0.00000494979 
 
 
-
 
NC_010322  PputGB1_0061  two component heavy metal response transcriptional regulator  43.44 
 
 
224 aa  169  3e-41  Pseudomonas putida GB-1  Bacteria  normal  normal  0.0868462 
 
 
-
 
NC_007498  Pcar_3081  two component signal transduction response regulator  43.64 
 
 
223 aa  169  3e-41  Pelobacter carbinolicus DSM 2380  Bacteria  normal  n/a   
 
 
-
 
NC_010501  PputW619_0064  two component heavy metal response transcriptional regulator  43.44 
 
 
224 aa  169  3e-41  Pseudomonas putida W619  Bacteria  normal  hitchhiker  0.000118539 
 
 
-
 
NC_010001  Cphy_0196  two component transcriptional regulator  43.69 
 
 
226 aa  169  3e-41  Clostridium phytofermentans ISDg  Bacteria  normal  n/a   
 
 
-
 
NC_009512  Pput_0061  two component heavy metal response transcriptional regulator  43.44 
 
 
224 aa  169  3e-41  Pseudomonas putida F1  Bacteria  normal  0.382659  hitchhiker  0.0034413 
 
 
-
 
NC_013730  Slin_1849  two component transcriptional regulator, winged helix family  41.7 
 
 
228 aa  168  5e-41  Spirosoma linguale DSM 74  Bacteria  normal  0.418833  normal 
 
 
-
 
NC_011729  PCC7424_5018  two component transcriptional regulator, winged helix family  44.8 
 
 
226 aa  168  5e-41  Cyanothece sp. PCC 7424  Bacteria  n/a    normal 
 
 
-
 
NC_008752  Aave_3002  two component transcriptional regulator  45.7 
 
 
230 aa  168  5e-41  Acidovorax citrulli AAC00-1  Bacteria  normal  0.67465  normal  0.369251 
 
 
-
 
NC_011729  PCC7424_4628  two component transcriptional regulator, winged helix family  42.6 
 
 
224 aa  168  6e-41  Cyanothece sp. PCC 7424  Bacteria  n/a    hitchhiker  0.000289587 
 
 
-
 
NC_007644  Moth_1478  two component transcriptional regulator  42.73 
 
 
240 aa  167  9e-41  Moorella thermoacetica ATCC 39073  Bacteria  hitchhiker  0.0000111909  normal 
 
 
-
 
NC_013171  Apre_0086  two component transcriptional regulator, winged helix family  41.82 
 
 
223 aa  167  1e-40  Anaerococcus prevotii DSM 20548  Bacteria  hitchhiker  0.00000430601  n/a   
 
 
-
 
NC_013203  Apar_0090  two component transcriptional regulator, winged helix family  43.14 
 
 
226 aa  167  1e-40  Atopobium parvulum DSM 20469  Bacteria  normal  normal 
 
 
-
 
NC_008699  Noca_1598  response regulator receiver  44.55 
 
 
226 aa  166  2e-40  Nocardioides sp. JS614  Bacteria  normal  n/a   
 
 
-
 
NC_013730  Slin_4793  two component transcriptional regulator, winged helix family  43.64 
 
 
225 aa  166  2.9999999999999998e-40  Spirosoma linguale DSM 74  Bacteria  normal  normal 
 
 
-
 
NC_009664  Krad_1806  two component transcriptional regulator, winged helix family  45.45 
 
 
225 aa  166  2.9999999999999998e-40  Kineococcus radiotolerans SRS30216  Bacteria  normal  0.0205791  normal  0.258829 
 
 
-
 
NC_007517  Gmet_3383  two component transcriptional regulator  41.82 
 
 
224 aa  165  4e-40  Geobacter metallireducens GS-15  Bacteria  normal  normal 
 
 
-
 
NC_008347  Mmar10_0943  two component transcriptional regulator  44.8 
 
 
223 aa  165  4e-40  Maricaulis maris MCS10  Bacteria  normal  0.0172896  normal  0.994999 
 
 
-
 
NC_009012  Cthe_0799  two component transcriptional regulator  40.72 
 
 
225 aa  165  4e-40  Clostridium thermocellum ATCC 27405  Bacteria  normal  n/a   
 
 
-
 
NC_013730  Slin_2552  two component transcriptional regulator, winged helix family  41.59 
 
 
230 aa  164  8e-40  Spirosoma linguale DSM 74  Bacteria  hitchhiker  0.0000276879  normal  0.180215 
 
 
-
 
NC_009997  Sbal195_0632  two component transcriptional regulator  41.96 
 
 
227 aa  164  8e-40  Shewanella baltica OS195  Bacteria  normal  0.157641  normal 
 
 
-
 
NC_009665  Shew185_0604  two component transcriptional regulator  41.96 
 
 
227 aa  164  8e-40  Shewanella baltica OS185  Bacteria  decreased coverage  0.00704602  n/a   
 
 
-
 
NC_007298  Daro_2259  two component heavy metal response transcriptional regulator  45.29 
 
 
225 aa  164  1.0000000000000001e-39  Dechloromonas aromatica RCB  Bacteria  normal  normal 
 
 
-
 
NC_012034  Athe_0280  two component transcriptional regulator, winged helix family  40.45 
 
 
225 aa  164  1.0000000000000001e-39  Anaerocellum thermophilum DSM 6725  Bacteria  normal  n/a   
 
 
-
 
NC_009456  VC0395_0990  transcriptional regulator  42.53 
 
 
224 aa  164  1.0000000000000001e-39  Vibrio cholerae O395  Bacteria  hitchhiker  0.000166767  n/a   
 
 
-
 
NC_009439  Pmen_1174  two component heavy metal response transcriptional regulator  43.05 
 
 
224 aa  164  1.0000000000000001e-39  Pseudomonas mendocina ymp  Bacteria  normal  0.216853  normal 
 
 
-
 
NC_009486  Tpet_0521  two component transcriptional regulator  42.66 
 
 
223 aa  163  2.0000000000000002e-39  Thermotoga petrophila RKU-1  Bacteria  normal  0.720367  n/a   
 
 
-
 
NC_012918  GM21_0227  two component transcriptional regulator, winged helix family  43.64 
 
 
224 aa  163  2.0000000000000002e-39  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_009511  Swit_4516  two component transcriptional regulator  44.09 
 
 
225 aa  163  2.0000000000000002e-39  Sphingomonas wittichii RW1  Bacteria  normal  0.158523  normal 
 
 
-
 
NC_010676  Bphyt_5224  two component heavy metal response transcriptional regulator, winged helix family  44.55 
 
 
225 aa  162  3e-39  Burkholderia phytofirmans PsJN  Bacteria  normal  0.57611  normal 
 
 
-
 
NC_011662  Tmz1t_3985  two component heavy metal response transcriptional regulator, winged helix family  44.59 
 
 
226 aa  162  3e-39  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_009565  TBFG_10613  two component system DNA binding transcriptional regulatory protein tcrA  43.64 
 
 
253 aa  162  3e-39  Mycobacterium tuberculosis F11  Bacteria  hitchhiker  0.0000000499525  normal  0.750249 
 
 
-
 
NC_002977  MCA2330  DNA-binding response regulator  43.18 
 
 
228 aa  162  4.0000000000000004e-39  Methylococcus capsulatus str. Bath  Bacteria  normal  n/a   
 
 
-
 
NC_010571  Oter_1727  two component transcriptional regulator  45.16 
 
 
228 aa  162  4.0000000000000004e-39  Opitutus terrae PB90-1  Bacteria  normal  0.284746  normal 
 
 
-
 
NC_010001  Cphy_1620  two component transcriptional regulator  40.27 
 
 
227 aa  162  5.0000000000000005e-39  Clostridium phytofermentans ISDg  Bacteria  hitchhiker  0.000174219  n/a   
 
 
-
 
NC_011726  PCC8801_1416  two component transcriptional regulator, winged helix family  41.63 
 
 
225 aa  161  6e-39  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_013730  Slin_0919  two component transcriptional regulator, winged helix family  42.73 
 
 
223 aa  161  6e-39  Spirosoma linguale DSM 74  Bacteria  normal  normal  0.682864 
 
 
-
 
NC_013161  Cyan8802_1445  two component transcriptional regulator, winged helix family  41.63 
 
 
225 aa  161  6e-39  Cyanothece sp. PCC 8802  Bacteria  normal  normal 
 
 
-
 
NC_009654  Mmwyl1_0419  two component transcriptional regulator  43.95 
 
 
229 aa  161  7e-39  Marinomonas sp. MWYL1  Bacteria  normal  0.509677  normal 
 
 
-
 
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