More than 300 homologs were found in PanDaTox collection
for query gene TRQ2_0085 on replicon NC_010483
Organism: Thermotoga sp. RQ2



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_010483  TRQ2_0085  response regulator receiver protein  100 
 
 
253 aa  507  1e-143  Thermotoga sp. RQ2  Bacteria  normal  0.7943  n/a   
 
 
-
 
NC_009486  Tpet_0085  response regulator receiver protein  100 
 
 
253 aa  507  1e-143  Thermotoga petrophila RKU-1  Bacteria  hitchhiker  0.0000252622  n/a   
 
 
-
 
NC_007644  Moth_2152  response regulator receiver modulated diguanylate cyclase  26.64 
 
 
273 aa  100  2e-20  Moorella thermoacetica ATCC 39073  Bacteria  normal  normal  0.0525986 
 
 
-
 
NC_013385  Adeg_1202  response regulator receiver protein  27.35 
 
 
270 aa  94.7  1e-18  Ammonifex degensii KC4  Bacteria  normal  0.0510958  n/a   
 
 
-
 
NC_010320  Teth514_1977  response regulator receiver protein  29.62 
 
 
266 aa  94.4  2e-18  Thermoanaerobacter sp. X514  Bacteria  normal  n/a   
 
 
-
 
NC_007644  Moth_0692  response regulator receiver modulated diguanylate cyclase  25.82 
 
 
270 aa  87.8  2e-16  Moorella thermoacetica ATCC 39073  Bacteria  normal  0.370043  unclonable  0.00000000838432 
 
 
-
 
NC_009253  Dred_1554  response regulator receiver modulated diguanylate cyclase  26.47 
 
 
419 aa  84.7  0.000000000000001  Desulfotomaculum reducens MI-1  Bacteria  normal  n/a   
 
 
-
 
NC_011145  AnaeK_3251  two component, sigma54 specific, transcriptional regulator, Fis family  36.28 
 
 
465 aa  84.7  0.000000000000001  Anaeromyxobacter sp. K  Bacteria  normal  n/a   
 
 
-
 
NC_011899  Hore_10620  response regulator receiver protein  36.44 
 
 
122 aa  74.7  0.000000000001  Halothermothrix orenii H 168  Bacteria  hitchhiker  0.00212992  n/a   
 
 
-
 
NC_007498  Pcar_2015  two component hybrid sensor response regulator  33.06 
 
 
391 aa  73.6  0.000000000003  Pelobacter carbinolicus DSM 2380  Bacteria  normal  n/a   
 
 
-
 
NC_013440  Hoch_2280  two component, sigma54 specific, transcriptional regulator, Fis family  31.03 
 
 
453 aa  73.6  0.000000000003  Haliangium ochraceum DSM 14365  Bacteria  normal  normal  0.620123 
 
 
-
 
NC_013037  Dfer_2749  two component, sigma54 specific, transcriptional regulator, Fis family  29.49 
 
 
486 aa  73.2  0.000000000004  Dyadobacter fermentans DSM 18053  Bacteria  normal  0.778475  normal  0.579466 
 
 
-
 
NC_013522  Taci_1321  response regulator receiver protein  33.33 
 
 
120 aa  72.8  0.000000000005  Thermanaerovibrio acidaminovorans DSM 6589  Bacteria  normal  n/a   
 
 
-
 
NC_010814  Glov_1377  two component, sigma54 specific, transcriptional regulator, Fis family  33.33 
 
 
462 aa  72.8  0.000000000005  Geobacter lovleyi SZ  Bacteria  normal  0.244526  n/a   
 
 
-
 
NC_011146  Gbem_2407  response regulator receiver modulated metal dependent phosphohydrolase  30.51 
 
 
347 aa  71.2  0.00000000001  Geobacter bemidjiensis Bem  Bacteria  normal  0.21688  n/a   
 
 
-
 
NC_007517  Gmet_0010  PAS/PAC sensor hybrid histidine kinase  31.58 
 
 
508 aa  71.2  0.00000000001  Geobacter metallireducens GS-15  Bacteria  normal  0.0502065  normal 
 
 
-
 
NC_011146  Gbem_2715  response regulator receiver modulated diguanylate cyclase  22.34 
 
 
314 aa  71.6  0.00000000001  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_013173  Dbac_2666  two component, sigma54 specific, transcriptional regulator, Fis family  33.65 
 
 
459 aa  70.9  0.00000000002  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  n/a   
 
 
-
 
NC_013223  Dret_2242  two component, sigma54 specific, transcriptional regulator, Fis family  33.33 
 
 
464 aa  70.9  0.00000000002  Desulfohalobium retbaense DSM 5692  Bacteria  normal  normal  0.719582 
 
 
-
 
NC_012918  GM21_1811  response regulator receiver modulated metal dependent phosphohydrolase  30.51 
 
 
347 aa  71.2  0.00000000002  Geobacter sp. M21  Bacteria  n/a    hitchhiker  0.00843757 
 
 
-
 
NC_011769  DvMF_1260  two component, sigma54 specific, transcriptional regulator, Fis family  31.86 
 
 
452 aa  70.9  0.00000000002  Desulfovibrio vulgaris str. 'Miyazaki F'  Bacteria  n/a    hitchhiker  0.0000000000141339 
 
 
-
 
NC_002939  GSU0008  sensory box histidine kinase/response regulator  33.04 
 
 
516 aa  70.1  0.00000000003  Geobacter sulfurreducens PCA  Bacteria  normal  n/a   
 
 
-
 
NC_013385  Adeg_0532  two component, sigma54 specific, transcriptional regulator, Fis family  32.03 
 
 
470 aa  70.5  0.00000000003  Ammonifex degensii KC4  Bacteria  hitchhiker  0.00706375  n/a   
 
 
-
 
NC_009483  Gura_0495  two component, sigma-54 specific, Fis family transcriptional regulator  33.33 
 
 
456 aa  70.1  0.00000000004  Geobacter uraniireducens Rf4  Bacteria  normal  n/a   
 
 
-
 
NC_010505  Mrad2831_0204  two component transcriptional regulator  33.05 
 
 
242 aa  69.7  0.00000000004  Methylobacterium radiotolerans JCM 2831  Bacteria  decreased coverage  0.00392261  normal 
 
 
-
 
NC_009675  Anae109_1951  two component, sigma54 specific, Fis family transcriptional regulator  29.77 
 
 
470 aa  69.3  0.00000000005  Anaeromyxobacter sp. Fw109-5  Bacteria  normal  0.516267  normal 
 
 
-
 
NC_010814  Glov_1826  two component, sigma54 specific, transcriptional regulator, Fis family  31.82 
 
 
455 aa  69.3  0.00000000006  Geobacter lovleyi SZ  Bacteria  normal  0.048867  n/a   
 
 
-
 
NC_011830  Dhaf_4140  response regulator receiver protein  34.19 
 
 
120 aa  68.9  0.00000000007  Desulfitobacterium hafniense DCB-2  Bacteria  hitchhiker  0.000406755  n/a   
 
 
-
 
NC_010718  Nther_0252  response regulator receiver protein  31.2 
 
 
239 aa  68.9  0.00000000007  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  normal  0.114255 
 
 
-
 
NC_011729  PCC7424_2841  response regulator receiver modulated GAF sensor protein  31.2 
 
 
308 aa  68.9  0.00000000007  Cyanothece sp. PCC 7424  Bacteria  n/a    normal  0.585847 
 
 
-
 
NC_008781  Pnap_1956  two component, sigma54 specific, Fis family transcriptional regulator  33.09 
 
 
486 aa  68.9  0.00000000007  Polaromonas naphthalenivorans CJ2  Bacteria  normal  0.696783  normal 
 
 
-
 
NC_013501  Rmar_0513  two component transcriptional regulator, winged helix family  31.4 
 
 
228 aa  68.6  0.00000000009  Rhodothermus marinus DSM 4252  Bacteria  normal  0.985837  n/a   
 
 
-
 
NC_011899  Hore_07590  response regulator receiver protein  30.58 
 
 
122 aa  68.6  0.00000000009  Halothermothrix orenii H 168  Bacteria  hitchhiker  0.00000000535524  n/a   
 
 
-
 
NC_010718  Nther_1407  response regulator receiver protein  30.83 
 
 
120 aa  68.2  0.0000000001  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  0.926591  normal 
 
 
-
 
NC_009675  Anae109_1105  two component, sigma54 specific, Fis family transcriptional regulator  32.48 
 
 
475 aa  68.2  0.0000000001  Anaeromyxobacter sp. Fw109-5  Bacteria  normal  0.926771  normal  0.835973 
 
 
-
 
NC_011899  Hore_16930  response regulator receiver protein  37.39 
 
 
117 aa  68.6  0.0000000001  Halothermothrix orenii H 168  Bacteria  normal  n/a   
 
 
-
 
NC_011769  DvMF_1991  response regulator receiver protein  34.86 
 
 
153 aa  68.6  0.0000000001  Desulfovibrio vulgaris str. 'Miyazaki F'  Bacteria  n/a    normal 
 
 
-
 
NC_002939  GSU1495  sigma-54 dependent DNA-binding response regulator  37.27 
 
 
458 aa  67.8  0.0000000002  Geobacter sulfurreducens PCA  Bacteria  normal  0.301103  n/a   
 
 
-
 
NC_012793  GWCH70_3334  response regulator receiver protein  30 
 
 
120 aa  67.8  0.0000000002  Geobacillus sp. WCH70  Bacteria  normal  n/a   
 
 
-
 
NC_012918  GM21_1525  response regulator receiver modulated diguanylate cyclase  30.53 
 
 
316 aa  67.4  0.0000000002  Geobacter sp. M21  Bacteria  n/a    hitchhiker  2.15223e-23 
 
 
-
 
NC_007517  Gmet_0555  two component, sigma54 specific, Fis family transcriptional regulator  29.91 
 
 
457 aa  67.4  0.0000000002  Geobacter metallireducens GS-15  Bacteria  normal  normal 
 
 
-
 
NC_007760  Adeh_1908  two component, sigma54 specific, Fis family transcriptional regulator  29.77 
 
 
473 aa  67.8  0.0000000002  Anaeromyxobacter dehalogenans 2CP-C  Bacteria  normal  n/a   
 
 
-
 
NC_009253  Dred_2382  response regulator receiver protein  28.69 
 
 
122 aa  67.8  0.0000000002  Desulfotomaculum reducens MI-1  Bacteria  normal  n/a   
 
 
-
 
NC_012560  Avin_11120  Response regulator, sigma54-dependent regulatory protein; AlgB  26.43 
 
 
448 aa  67.4  0.0000000002  Azotobacter vinelandii DJ  Bacteria  normal  n/a   
 
 
-
 
NC_011146  Gbem_0283  two component, sigma54 specific, transcriptional regulator, Fis family  32.48 
 
 
456 aa  67.4  0.0000000002  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_008609  Ppro_2968  response regulator receiver sensor signal transduction histidine kinase  29.17 
 
 
392 aa  67.4  0.0000000002  Pelobacter propionicus DSM 2379  Bacteria  normal  n/a   
 
 
-
 
NC_010725  Mpop_0949  two component transcriptional regulator, winged helix family  33.04 
 
 
229 aa  67.4  0.0000000002  Methylobacterium populi BJ001  Bacteria  normal  0.0140851  normal 
 
 
-
 
NC_012918  GM21_0268  two component, sigma54 specific, transcriptional regulator, Fis family  32.48 
 
 
456 aa  67.4  0.0000000002  Geobacter sp. M21  Bacteria  n/a    normal  0.0540037 
 
 
-
 
NC_011769  DvMF_1461  two component, sigma54 specific, transcriptional regulator, Fis family  29.73 
 
 
491 aa  67  0.0000000003  Desulfovibrio vulgaris str. 'Miyazaki F'  Bacteria  n/a    normal  0.750458 
 
 
-
 
NC_002947  PP_0133  two component, sigma54 specific, transcriptional regulator, Fis family  31.13 
 
 
448 aa  66.6  0.0000000003  Pseudomonas putida KT2440  Bacteria  normal  normal 
 
 
-
 
NC_013385  Adeg_2019  response regulator receiver protein  30.08 
 
 
123 aa  66.6  0.0000000003  Ammonifex degensii KC4  Bacteria  normal  n/a   
 
 
-
 
NC_007404  Tbd_0904  two component Fis family transcriptional regulator  29.32 
 
 
454 aa  67  0.0000000003  Thiobacillus denitrificans ATCC 25259  Bacteria  normal  0.629928  normal 
 
 
-
 
NC_010001  Cphy_2701  response regulator receiver protein  30.83 
 
 
120 aa  67  0.0000000003  Clostridium phytofermentans ISDg  Bacteria  decreased coverage  0.000335112  n/a   
 
 
-
 
NC_013440  Hoch_6827  response regulator receiver protein  25.61 
 
 
389 aa  67  0.0000000003  Haliangium ochraceum DSM 14365  Bacteria  normal  normal 
 
 
-
 
NC_009483  Gura_0009  multi-sensor signal transduction histidine kinase  28.12 
 
 
508 aa  67  0.0000000003  Geobacter uraniireducens Rf4  Bacteria  normal  n/a   
 
 
-
 
NC_008609  Ppro_3175  response regulator receiver sensor signal transduction histidine kinase  33.04 
 
 
370 aa  67  0.0000000003  Pelobacter propionicus DSM 2379  Bacteria  normal  0.768346  n/a   
 
 
-
 
NC_013223  Dret_0887  response regulator receiver modulated metal dependent phosphohydrolase  34.75 
 
 
496 aa  66.6  0.0000000003  Desulfohalobium retbaense DSM 5692  Bacteria  normal  0.384329  normal 
 
 
-
 
NC_009439  Pmen_0176  two-component response regulator AlgB  30.7 
 
 
450 aa  66.6  0.0000000004  Pseudomonas mendocina ymp  Bacteria  normal  normal 
 
 
-
 
NC_013205  Aaci_2784  response regulator receiver protein  30.83 
 
 
125 aa  66.2  0.0000000004  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  0.0945133  n/a   
 
 
-
 
NC_007520  Tcr_1444  two component, sigma54 specific, Fis family transcriptional regulator  33.33 
 
 
459 aa  66.6  0.0000000004  Thiomicrospira crunogena XCL-2  Bacteria  normal  n/a   
 
 
-
 
NC_013173  Dbac_3091  two component, sigma54 specific, transcriptional regulator, Fis family  33.9 
 
 
457 aa  66.6  0.0000000004  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  n/a   
 
 
-
 
NC_011726  PCC8801_1139  response regulator receiver modulated diguanylate cyclase  25 
 
 
308 aa  66.2  0.0000000004  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_008228  Patl_3049  two component, sigma54 specific, Fis family transcriptional regulator  31.86 
 
 
447 aa  66.2  0.0000000004  Pseudoalteromonas atlantica T6c  Bacteria  normal  n/a   
 
 
-
 
NC_009483  Gura_2678  two component, sigma-54 specific, Fis family transcriptional regulator  35.77 
 
 
457 aa  66.6  0.0000000004  Geobacter uraniireducens Rf4  Bacteria  normal  n/a   
 
 
-
 
NC_009512  Pput_0150  two component, sigma54 specific, Fis family transcriptional regulator  31.13 
 
 
448 aa  66.6  0.0000000004  Pseudomonas putida F1  Bacteria  normal  normal 
 
 
-
 
NC_013161  Cyan8802_1169  response regulator receiver modulated diguanylate cyclase  25 
 
 
308 aa  66.2  0.0000000004  Cyanothece sp. PCC 8802  Bacteria  normal  normal 
 
 
-
 
NC_012034  Athe_2159  response regulator receiver protein  29.17 
 
 
120 aa  66.6  0.0000000004  Anaerocellum thermophilum DSM 6725  Bacteria  hitchhiker  0.00200925  n/a   
 
 
-
 
NC_009656  PSPA7_6282  two-component response regulator AlgB  30.19 
 
 
449 aa  66.2  0.0000000005  Pseudomonas aeruginosa PA7  Bacteria  normal  n/a   
 
 
-
 
NC_011891  A2cp1_2056  two component, sigma54 specific, transcriptional regulator, Fis family  29.01 
 
 
473 aa  66.2  0.0000000005  Anaeromyxobacter dehalogenans 2CP-1  Bacteria  normal  0.732718  n/a   
 
 
-
 
NC_011145  AnaeK_1971  two component, sigma54 specific, transcriptional regulator, Fis family  29.01 
 
 
473 aa  66.2  0.0000000005  Anaeromyxobacter sp. K  Bacteria  normal  0.0887215  n/a   
 
 
-
 
NC_008463  PA14_72380  two-component response regulator AlgB  27.59 
 
 
449 aa  66.2  0.0000000005  Pseudomonas aeruginosa UCBPP-PA14  Bacteria  normal  0.415261  normal 
 
 
-
 
NC_013757  Gobs_1518  response regulator receiver modulated diguanylate cyclase  31.65 
 
 
767 aa  65.9  0.0000000005  Geodermatophilus obscurus DSM 43160  Bacteria  normal  0.0706082  n/a   
 
 
-
 
NC_008639  Cpha266_1801  integral membrane sensor hybrid histidine kinase  32.2 
 
 
699 aa  66.2  0.0000000005  Chlorobium phaeobacteroides DSM 266  Bacteria  unclonable  0.00000631548  n/a   
 
 
-
 
NC_011761  AFE_0185  type IV fimbriae expression regulatory protein PilR, putative  30 
 
 
445 aa  66.2  0.0000000005  Acidithiobacillus ferrooxidans ATCC 23270  Bacteria  normal  0.103259  n/a   
 
 
-
 
NC_004578  PSPTO_0334  alginate biosynthesis transcriptional regulatory protein AlgB  30.19 
 
 
448 aa  65.9  0.0000000006  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  0.368066  n/a   
 
 
-
 
NC_007005  Psyr_0263  helix-turn-helix, Fis-type  30.19 
 
 
448 aa  65.9  0.0000000006  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  normal 
 
 
-
 
NC_010524  Lcho_0901  two component LuxR family transcriptional regulator  30 
 
 
235 aa  65.9  0.0000000006  Leptothrix cholodnii SP-6  Bacteria  n/a    normal 
 
 
-
 
NC_007963  Csal_0246  nitrogen metabolism transcriptional regulator, NtrC, Fis family  30.77 
 
 
469 aa  65.9  0.0000000006  Chromohalobacter salexigens DSM 3043  Bacteria  normal  0.487777  n/a   
 
 
-
 
NC_008009  Acid345_3269  two component, sigma54 specific, Fis family transcriptional regulator  25.53 
 
 
467 aa  65.9  0.0000000006  Candidatus Koribacter versatilis Ellin345  Bacteria  normal  normal  0.382263 
 
 
-
 
NC_009943  Dole_1360  response regulator receiver sensor signal transduction histidine kinase  33.93 
 
 
403 aa  65.5  0.0000000007  Desulfococcus oleovorans Hxd3  Bacteria  normal  n/a   
 
 
-
 
NC_013173  Dbac_2713  two component, sigma54 specific, transcriptional regulator, Fis family  34.78 
 
 
454 aa  65.9  0.0000000007  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  n/a   
 
 
-
 
NC_013223  Dret_0548  two component, sigma54 specific, transcriptional regulator, Fis family  29.87 
 
 
452 aa  65.5  0.0000000008  Desulfohalobium retbaense DSM 5692  Bacteria  normal  0.902927  normal 
 
 
-
 
NC_007492  Pfl01_4221  two component transcriptional regulator  29.31 
 
 
240 aa  65.5  0.0000000008  Pseudomonas fluorescens Pf0-1  Bacteria  normal  0.430301  normal  0.246318 
 
 
-
 
NC_009675  Anae109_0732  two component, sigma54 specific, Fis family transcriptional regulator  28.1 
 
 
471 aa  65.5  0.0000000008  Anaeromyxobacter sp. Fw109-5  Bacteria  normal  0.121473  normal 
 
 
-
 
NC_008554  Sfum_0827  two component, sigma54 specific, Fis family transcriptional regulator  24.77 
 
 
447 aa  65.5  0.0000000008  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  normal 
 
 
-
 
NC_008751  Dvul_2845  two component, sigma54 specific, Fis family transcriptional regulator  32.48 
 
 
454 aa  65.5  0.0000000008  Desulfovibrio vulgaris DP4  Bacteria  normal  normal 
 
 
-
 
NC_011831  Cagg_1858  two component transcriptional regulator, winged helix family  32.77 
 
 
227 aa  65.5  0.0000000009  Chloroflexus aggregans DSM 9485  Bacteria  normal  normal 
 
 
-
 
NC_010322  PputGB1_0148  two component, sigma54 specific, Fis family transcriptional regulator  30.19 
 
 
448 aa  65.5  0.0000000009  Pseudomonas putida GB-1  Bacteria  normal  normal  0.837927 
 
 
-
 
NC_007912  Sde_2191  diguanylate cyclase/phosphodiesterase  31.62 
 
 
497 aa  65.5  0.0000000009  Saccharophagus degradans 2-40  Bacteria  normal  normal 
 
 
-
 
NC_002936  DET0624  response regulator  28.47 
 
 
334 aa  64.7  0.000000001  Dehalococcoides ethenogenes 195  Bacteria  normal  n/a   
 
 
-
 
NC_004578  PSPTO_0352  nitrogen regulation protein NR(I)  29.66 
 
 
478 aa  65.1  0.000000001  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  n/a   
 
 
-
 
NC_007333  Tfu_0343  response regulator receiver  30.89 
 
 
232 aa  65.1  0.000000001  Thermobifida fusca YX  Bacteria  normal  0.86362  n/a   
 
 
-
 
NC_007492  Pfl01_0046  two-component response regulator AlgB  30.19 
 
 
448 aa  64.7  0.000000001  Pseudomonas fluorescens Pf0-1  Bacteria  normal  normal  0.384971 
 
 
-
 
NC_007492  Pfl01_0339  nitrogen metabolism transcriptional regulator, NtrC, Fis family  29.66 
 
 
478 aa  64.7  0.000000001  Pseudomonas fluorescens Pf0-1  Bacteria  normal  normal 
 
 
-
 
NC_011146  Gbem_0080  response regulator receiver modulated metal dependent phosphohydrolase  33.91 
 
 
357 aa  65.1  0.000000001  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_011146  Gbem_1426  two component, sigma54 specific, transcriptional regulator, Fis family  30.51 
 
 
444 aa  65.1  0.000000001  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_011769  DvMF_2109  two component, sigma54 specific, transcriptional regulator, Fis family  32.46 
 
 
515 aa  64.7  0.000000001  Desulfovibrio vulgaris str. 'Miyazaki F'  Bacteria  n/a    normal 
 
 
-
 
NC_011891  A2cp1_1183  two component, sigma54 specific, transcriptional regulator, Fis family  30.33 
 
 
481 aa  64.7  0.000000001  Anaeromyxobacter dehalogenans 2CP-1  Bacteria  normal  n/a   
 
 
-
 
NC_010501  PputW619_5095  two component, sigma54 specific, Fis family transcriptional regulator  30.19 
 
 
448 aa  64.7  0.000000001  Pseudomonas putida W619  Bacteria  normal  normal  0.262214 
 
 
-
 
NC_011206  Lferr_0364  two component, sigma54 specific, transcriptional regulator, Fis family  29.38 
 
 
451 aa  65.1  0.000000001  Acidithiobacillus ferrooxidans ATCC 53993  Bacteria  normal  normal  0.48055 
 
 
-
 
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