More than 300 homologs were found in PanDaTox collection
for query gene Rmet_5323 on replicon NC_007974
Organism: Cupriavidus metallidurans CH34



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_007974  Rmet_5323  transcriptional regulator two component heavy metal regulatory response ZniR  100 
 
 
206 aa  415  9.999999999999999e-116  Cupriavidus metallidurans CH34  Bacteria  normal  normal  0.844748 
 
 
-
 
NC_010683  Rpic_4984  two component transcriptional regulator, LuxR family  71.94 
 
 
201 aa  287  7e-77  Ralstonia pickettii 12J  Bacteria  normal  normal  0.0145131 
 
 
-
 
NC_012856  Rpic12D_2528  two component transcriptional regulator, LuxR family  71.94 
 
 
201 aa  287  7e-77  Ralstonia pickettii 12D  Bacteria  normal  normal  0.0341229 
 
 
-
 
NC_010682  Rpic_2943  two component transcriptional regulator, LuxR family  71.57 
 
 
201 aa  287  9e-77  Ralstonia pickettii 12J  Bacteria  normal  normal 
 
 
-
 
NC_010682  Rpic_1673  two component transcriptional regulator, LuxR family  71.57 
 
 
201 aa  287  9e-77  Ralstonia pickettii 12J  Bacteria  normal  0.619826  normal 
 
 
-
 
NC_009485  BBta_1549  LuxR transcriptional regulator  65.82 
 
 
201 aa  259  2e-68  Bradyrhizobium sp. BTAi1  Bacteria  normal  0.355184  normal  0.152747 
 
 
-
 
NC_010505  Mrad2831_4715  two component LuxR family transcriptional regulator  53.72 
 
 
196 aa  197  6e-50  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  normal 
 
 
-
 
NC_010571  Oter_0804  two component LuxR family transcriptional regulator  43 
 
 
204 aa  134  7.000000000000001e-31  Opitutus terrae PB90-1  Bacteria  normal  normal 
 
 
-
 
NC_009668  Oant_2873  two component LuxR family transcriptional regulator  38.12 
 
 
216 aa  130  1.0000000000000001e-29  Ochrobactrum anthropi ATCC 49188  Bacteria  normal  n/a   
 
 
-
 
NC_011729  PCC7424_2881  two component transcriptional regulator, LuxR family  33.81 
 
 
212 aa  119  3e-26  Cyanothece sp. PCC 7424  Bacteria  n/a    normal 
 
 
-
 
NC_008687  Pden_3311  response regulator receiver protein  49.58 
 
 
321 aa  119  3e-26  Paracoccus denitrificans PD1222  Bacteria  normal  normal  0.479786 
 
 
-
 
NC_004578  PSPTO_4080  DNA-binding response regulator, LuxR family  35.5 
 
 
222 aa  115  3e-25  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  0.542388  n/a   
 
 
-
 
NC_012850  Rleg_2665  response regulator receiver protein  44.54 
 
 
133 aa  114  1.0000000000000001e-24  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  0.0531061  normal 
 
 
-
 
NC_011369  Rleg2_2336  response regulator receiver protein  44.54 
 
 
133 aa  112  3e-24  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  0.103968  normal  0.760096 
 
 
-
 
NC_008312  Tery_4323  two component LuxR family transcriptional regulator  32.86 
 
 
215 aa  110  2.0000000000000002e-23  Trichodesmium erythraeum IMS101  Bacteria  normal  0.115662  normal  0.727411 
 
 
-
 
NC_013161  Cyan8802_1605  two component transcriptional regulator, LuxR family  30.23 
 
 
216 aa  109  3e-23  Cyanothece sp. PCC 8802  Bacteria  normal  normal 
 
 
-
 
NC_011726  PCC8801_1580  two component transcriptional regulator, LuxR family  30.23 
 
 
216 aa  109  3e-23  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_011884  Cyan7425_5215  two component transcriptional regulator, LuxR family  31.47 
 
 
217 aa  103  2e-21  Cyanothece sp. PCC 7425  Bacteria  normal  normal 
 
 
-
 
NC_011891  A2cp1_2938  two component transcriptional regulator, LuxR family  34.74 
 
 
215 aa  103  2e-21  Anaeromyxobacter dehalogenans 2CP-1  Bacteria  normal  n/a   
 
 
-
 
NC_007760  Adeh_2754  two component LuxR family transcriptional regulator  34.74 
 
 
215 aa  103  2e-21  Anaeromyxobacter dehalogenans 2CP-C  Bacteria  normal  0.221671  n/a   
 
 
-
 
NC_011145  AnaeK_2846  two component transcriptional regulator, LuxR family  34.74 
 
 
215 aa  103  2e-21  Anaeromyxobacter sp. K  Bacteria  normal  0.243379  n/a   
 
 
-
 
NC_007413  Ava_0301  two component LuxR family transcriptional regulator  31.88 
 
 
231 aa  102  4e-21  Anabaena variabilis ATCC 29413  Bacteria  normal  0.54347  normal 
 
 
-
 
NC_007413  Ava_3628  two component LuxR family transcriptional regulator  30.39 
 
 
225 aa  100  1e-20  Anabaena variabilis ATCC 29413  Bacteria  normal  0.717242  normal  0.142765 
 
 
-
 
NC_014248  Aazo_2887  LuxR family two component transcriptional regulator  30.39 
 
 
225 aa  100  1e-20  'Nostoc azollae' 0708  Bacteria  normal  0.526109  n/a   
 
 
-
 
NC_013730  Slin_1040  response regulator receiver sensor signal transduction histidine kinase  45 
 
 
365 aa  100  2e-20  Spirosoma linguale DSM 74  Bacteria  normal  normal 
 
 
-
 
NC_008688  Pden_4740  two component LuxR family transcriptional regulator  39.47 
 
 
160 aa  99.4  4e-20  Paracoccus denitrificans PD1222  Bacteria  normal  0.318753  normal  0.272493 
 
 
-
 
NC_009675  Anae109_2743  two component LuxR family transcriptional regulator  33.8 
 
 
215 aa  98.6  5e-20  Anaeromyxobacter sp. Fw109-5  Bacteria  normal  0.231043  normal 
 
 
-
 
NC_009674  Bcer98_0802  two component transcriptional regulator  36.05 
 
 
220 aa  97.8  9e-20  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  n/a   
 
 
-
 
NC_011884  Cyan7425_4627  two component transcriptional regulator, LuxR family  29.73 
 
 
226 aa  97.4  1e-19  Cyanothece sp. PCC 7425  Bacteria  normal  normal 
 
 
-
 
NC_013061  Phep_2522  response regulator receiver  31.73 
 
 
229 aa  97.8  1e-19  Pedobacter heparinus DSM 2366  Bacteria  normal  0.661278  normal 
 
 
-
 
NC_013757  Gobs_1518  response regulator receiver modulated diguanylate cyclase  42.11 
 
 
767 aa  96.3  3e-19  Geodermatophilus obscurus DSM 43160  Bacteria  normal  0.0706082  n/a   
 
 
-
 
NC_013730  Slin_3553  transcriptional regulator, Crp/Fnr family  44.8 
 
 
348 aa  95.5  4e-19  Spirosoma linguale DSM 74  Bacteria  normal  normal  0.528491 
 
 
-
 
NC_011729  PCC7424_2267  two component transcriptional regulator, AraC family  42.5 
 
 
265 aa  95.5  5e-19  Cyanothece sp. PCC 7424  Bacteria  n/a    hitchhiker  0.00808217 
 
 
-
 
NC_010180  BcerKBAB4_5471  two component transcriptional regulator  41.8 
 
 
221 aa  95.1  6e-19  Bacillus weihenstephanensis KBAB4  Bacteria  hitchhiker  0.00800002  hitchhiker  0.0013378 
 
 
-
 
NC_011726  PCC8801_1812  two component transcriptional regulator, LuxR family  29.44 
 
 
231 aa  94.7  9e-19  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_007413  Ava_0065  response regulator receiver domain-containing protein  32.95 
 
 
196 aa  94.7  9e-19  Anabaena variabilis ATCC 29413  Bacteria  normal  0.670969  normal  0.0252366 
 
 
-
 
NC_013161  Cyan8802_1838  two component transcriptional regulator, LuxR family  29.44 
 
 
231 aa  94.7  9e-19  Cyanothece sp. PCC 8802  Bacteria  normal  normal 
 
 
-
 
NC_010184  BcerKBAB4_2424  two component transcriptional regulator  40.16 
 
 
221 aa  94.4  1e-18  Bacillus weihenstephanensis KBAB4  Bacteria  normal  0.0245011  n/a   
 
 
-
 
NC_003909  BCE_2749  transcription response regulator-like protein  40.16 
 
 
221 aa  94.4  1e-18  Bacillus cereus ATCC 10987  Bacteria  decreased coverage  0.00061025  n/a   
 
 
-
 
NC_011772  BCG9842_B2563  transcriptional regulatory protein ResD  40.16 
 
 
221 aa  94.4  1e-18  Bacillus cereus G9842  Bacteria  normal  hitchhiker  0.00803163 
 
 
-
 
NC_014248  Aazo_2987  LuxR family two component transcriptional regulator  31 
 
 
231 aa  93.6  2e-18  'Nostoc azollae' 0708  Bacteria  normal  n/a   
 
 
-
 
NC_013061  Phep_2492  response regulator receiver  41.67 
 
 
352 aa  94  2e-18  Pedobacter heparinus DSM 2366  Bacteria  normal  0.570528  normal  0.0101485 
 
 
-
 
NC_011729  PCC7424_2022  response regulator receiver modulated diguanylate cyclase/phosphodiesterase  37.32 
 
 
589 aa  93.6  2e-18  Cyanothece sp. PCC 7424  Bacteria  n/a    normal 
 
 
-
 
NC_013730  Slin_1271  transcriptional regulator, Crp/Fnr family  43.33 
 
 
350 aa  92.8  3e-18  Spirosoma linguale DSM 74  Bacteria  normal  normal 
 
 
-
 
NC_009972  Haur_4308  response regulator receiver modulated diguanylate cyclase  33.33 
 
 
552 aa  92.8  3e-18  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  n/a   
 
 
-
 
NC_013501  Rmar_2360  response regulator receiver protein  45.86 
 
 
523 aa  92  5e-18  Rhodothermus marinus DSM 4252  Bacteria  normal  n/a   
 
 
-
 
NC_013730  Slin_1037  response regulator receiver protein  42.75 
 
 
247 aa  92  6e-18  Spirosoma linguale DSM 74  Bacteria  normal  normal 
 
 
-
 
NC_013440  Hoch_4952  response regulator receiver protein  39.34 
 
 
317 aa  91.7  7e-18  Haliangium ochraceum DSM 14365  Bacteria  normal  normal 
 
 
-
 
NC_007604  Synpcc7942_1860  two component LuxR family transcriptional regulator  31.65 
 
 
235 aa  91.7  7e-18  Synechococcus elongatus PCC 7942  Bacteria  normal  normal 
 
 
-
 
NC_008577  Shewana3_3184  two component transcriptional regulator  33.33 
 
 
237 aa  91.7  8e-18  Shewanella sp. ANA-3  Bacteria  normal  0.0220819  normal 
 
 
-
 
NC_009972  Haur_1474  response regulator receiver modulated metal dependent phosphohydrolase  35.75 
 
 
345 aa  91.3  9e-18  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  n/a   
 
 
-
 
NC_004347  SO_3594  transcriptional regulatory protein RstA, putative  33.33 
 
 
237 aa  90.9  1e-17  Shewanella oneidensis MR-1  Bacteria  n/a    n/a   
 
 
-
 
NC_011729  PCC7424_2955  two component transcriptional regulator, LuxR family  31.03 
 
 
231 aa  91.3  1e-17  Cyanothece sp. PCC 7424  Bacteria  n/a    normal  0.800941 
 
 
-
 
NC_007516  Syncc9605_2427  two component LuxR family transcriptional regulator  31.72 
 
 
245 aa  90.5  1e-17  Synechococcus sp. CC9605  Bacteria  normal  0.27075  normal 
 
 
-
 
NC_013161  Cyan8802_3680  two component transcriptional regulator, LuxR family  28.83 
 
 
223 aa  90.9  1e-17  Cyanothece sp. PCC 8802  Bacteria  normal  normal  0.233635 
 
 
-
 
NC_008010  Dgeo_2844  two component transcriptional regulator  36.54 
 
 
248 aa  91.3  1e-17  Deinococcus geothermalis DSM 11300  Bacteria  normal  n/a   
 
 
-
 
NC_008321  Shewmr4_3006  two component transcriptional regulator  33.33 
 
 
237 aa  90.9  1e-17  Shewanella sp. MR-4  Bacteria  hitchhiker  0.00000324706  normal  0.0671955 
 
 
-
 
NC_008322  Shewmr7_3087  two component transcriptional regulator  33.33 
 
 
237 aa  90.9  1e-17  Shewanella sp. MR-7  Bacteria  unclonable  0.00000126315  normal  0.467683 
 
 
-
 
NC_011726  PCC8801_2430  two component transcriptional regulator, LuxR family  28.83 
 
 
223 aa  90.9  1e-17  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_009092  Shew_0896  two component transcriptional regulator  34.27 
 
 
237 aa  89.7  2e-17  Shewanella loihica PV-4  Bacteria  unclonable  0.0000000189871  normal  0.423328 
 
 
-
 
NC_014248  Aazo_3807  AraC family two component transcriptional regulator  40.88 
 
 
289 aa  89.7  2e-17  'Nostoc azollae' 0708  Bacteria  normal  0.536318  n/a   
 
 
-
 
NC_007513  Syncc9902_2107  two component LuxR family transcriptional regulator  31.84 
 
 
245 aa  90.1  2e-17  Synechococcus sp. CC9902  Bacteria  normal  n/a   
 
 
-
 
NC_007794  Saro_2907  two component transcriptional regulator  38.58 
 
 
250 aa  90.1  2e-17  Novosphingobium aromaticivorans DSM 12444  Bacteria  normal  n/a   
 
 
-
 
NC_009901  Spea_0878  two component transcriptional regulator  32.53 
 
 
237 aa  89.7  2e-17  Shewanella pealeana ATCC 700345  Bacteria  hitchhiker  0.00260237  n/a   
 
 
-
 
NC_008700  Sama_2800  response regulator receiver protein  32.67 
 
 
236 aa  90.1  2e-17  Shewanella amazonensis SB2B  Bacteria  normal  0.0122786  normal 
 
 
-
 
NC_013037  Dfer_5316  transcriptional regulator, Crp/Fnr family  41.32 
 
 
354 aa  90.1  2e-17  Dyadobacter fermentans DSM 18053  Bacteria  normal  normal  0.100222 
 
 
-
 
NC_013037  Dfer_3651  two component transcriptional regulator, winged helix family  41.46 
 
 
228 aa  89.7  3e-17  Dyadobacter fermentans DSM 18053  Bacteria  normal  normal  0.0435949 
 
 
-
 
NC_007517  Gmet_1026  two component transcriptional regulator  37.69 
 
 
224 aa  89.7  3e-17  Geobacter metallireducens GS-15  Bacteria  normal  hitchhiker  0.000442073 
 
 
-
 
NC_009997  Sbal195_1104  two component transcriptional regulator  32.47 
 
 
237 aa  89.4  4e-17  Shewanella baltica OS195  Bacteria  hitchhiker  0.00308001  normal  0.0226787 
 
 
-
 
NC_014148  Plim_1485  response regulator receiver  32 
 
 
235 aa  89.4  4e-17  Planctomyces limnophilus DSM 3776  Bacteria  normal  0.236897  n/a   
 
 
-
 
NC_009438  Sputcn32_1010  two component transcriptional regulator  33.78 
 
 
237 aa  89.4  4e-17  Shewanella putrefaciens CN-32  Bacteria  hitchhiker  0.0000199702  n/a   
 
 
-
 
NC_011663  Sbal223_3287  two component transcriptional regulator, winged helix family  32.47 
 
 
237 aa  89.4  4e-17  Shewanella baltica OS223  Bacteria  hitchhiker  0.0000200523  normal  0.324308 
 
 
-
 
NC_009665  Shew185_1071  two component transcriptional regulator  32.47 
 
 
237 aa  89.4  4e-17  Shewanella baltica OS185  Bacteria  hitchhiker  0.0000676378  n/a   
 
 
-
 
NC_013132  Cpin_1224  two component transcriptional regulator, winged helix family  28.29 
 
 
227 aa  89  4e-17  Chitinophaga pinensis DSM 2588  Bacteria  normal  0.0117785  hitchhiker  0.00926138 
 
 
-
 
NC_008312  Tery_4491  two component LuxR family transcriptional regulator  29.65 
 
 
233 aa  89  4e-17  Trichodesmium erythraeum IMS101  Bacteria  normal  normal  0.697305 
 
 
-
 
NC_008700  Sama_2699  response regulator receiver protein  38.3 
 
 
233 aa  89.4  4e-17  Shewanella amazonensis SB2B  Bacteria  normal  0.824129  normal 
 
 
-
 
NC_009052  Sbal_1002  two component transcriptional regulator  32.47 
 
 
237 aa  89.4  4e-17  Shewanella baltica OS155  Bacteria  unclonable  0.000000000471824  n/a   
 
 
-
 
NC_007413  Ava_0649  response regulator receiver Signal transduction histidine kinase  35.58 
 
 
387 aa  89  5e-17  Anabaena variabilis ATCC 29413  Bacteria  normal  0.736737  normal  0.226718 
 
 
-
 
NC_013132  Cpin_5556  transcriptional regulator, Crp/Fnr family  38.28 
 
 
352 aa  89  5e-17  Chitinophaga pinensis DSM 2588  Bacteria  normal  0.487576  normal  0.0420739 
 
 
-
 
NC_009486  Tpet_0521  two component transcriptional regulator  32.35 
 
 
223 aa  89  5e-17  Thermotoga petrophila RKU-1  Bacteria  normal  0.720367  n/a   
 
 
-
 
NC_007413  Ava_2324  two component LuxR family transcriptional regulator  27.75 
 
 
245 aa  89  5e-17  Anabaena variabilis ATCC 29413  Bacteria  normal  0.42123  normal 
 
 
-
 
NC_009441  Fjoh_3460  two component transcriptional regulator  37.6 
 
 
238 aa  89  5e-17  Flavobacterium johnsoniae UW101  Bacteria  normal  0.0108229  n/a   
 
 
-
 
NC_013162  Coch_0209  two component transcriptional regulator, winged helix family  39.37 
 
 
251 aa  89  5e-17  Capnocytophaga ochracea DSM 7271  Bacteria  normal  n/a   
 
 
-
 
NC_012034  Athe_1456  two component transcriptional regulator, winged helix family  33.66 
 
 
223 aa  89  5e-17  Anaerocellum thermophilum DSM 6725  Bacteria  decreased coverage  0.000183373  n/a   
 
 
-
 
NC_013411  GYMC61_1696  two component transcriptional regulator, winged helix family  32.68 
 
 
224 aa  88.6  6e-17  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_007413  Ava_4889  two component AraC family transcriptional regulator  40.34 
 
 
288 aa  88.6  7e-17  Anabaena variabilis ATCC 29413  Bacteria  normal  0.298891  hitchhiker  0.00503781 
 
 
-
 
NC_007575  Suden_0884  two component transcriptional regulator  31.39 
 
 
218 aa  88.2  8e-17  Sulfurimonas denitrificans DSM 1251  Bacteria  normal  0.68851  n/a   
 
 
-
 
NC_007908  Rfer_0510  two component transcriptional regulator  34.71 
 
 
234 aa  88.2  8e-17  Rhodoferax ferrireducens T118  Bacteria  normal  n/a   
 
 
-
 
NC_011884  Cyan7425_0584  response regulator receiver protein  38.41 
 
 
216 aa  87.8  9e-17  Cyanothece sp. PCC 7425  Bacteria  normal  0.0767221  normal 
 
 
-
 
NC_010506  Swoo_1030  two component transcriptional regulator  33.11 
 
 
237 aa  87.8  9e-17  Shewanella woodyi ATCC 51908  Bacteria  hitchhiker  0.000000542446  normal  0.656047 
 
 
-
 
NC_009439  Pmen_0794  two component transcriptional regulator  35.76 
 
 
232 aa  87.4  1e-16  Pseudomonas mendocina ymp  Bacteria  normal  0.665518  normal 
 
 
-
 
NC_013947  Snas_2104  two component transcriptional regulator, winged helix family  30.85 
 
 
225 aa  87.4  1e-16  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  0.302064  normal  0.805943 
 
 
-
 
NC_009831  Ssed_0981  two component transcriptional regulator  33.11 
 
 
237 aa  87.4  1e-16  Shewanella sediminis HAW-EB3  Bacteria  normal  0.0593139  normal 
 
 
-
 
NC_011884  Cyan7425_0981  two component transcriptional regulator, LuxR family  26.05 
 
 
221 aa  87.8  1e-16  Cyanothece sp. PCC 7425  Bacteria  normal  normal  0.416641 
 
 
-
 
NC_013501  Rmar_0513  two component transcriptional regulator, winged helix family  35.88 
 
 
228 aa  87.8  1e-16  Rhodothermus marinus DSM 4252  Bacteria  normal  0.985837  n/a   
 
 
-
 
NC_009338  Mflv_1000  multi-sensor hybrid histidine kinase  37.88 
 
 
1161 aa  87  2e-16  Mycobacterium gilvum PYR-GCK  Bacteria  normal  normal 
 
 
-
 
NC_007335  PMN2A_1537  two component LuxR family transcriptional regulator  30.43 
 
 
242 aa  86.7  2e-16  Prochlorococcus marinus str. NATL2A  Bacteria  normal  n/a   
 
 
-
 
NC_014230  CA2559_09498  two-component system, transcriptional regulatory protein  38.33 
 
 
236 aa  86.7  2e-16  Croceibacter atlanticus HTCC2559  Bacteria  normal  n/a   
 
 
-
 
NC_008758  Pnap_4558  two component heavy metal response transcriptional regulator  31.5 
 
 
226 aa  87  2e-16  Polaromonas naphthalenivorans CJ2  Bacteria  normal  normal 
 
 
-
 
NC_008819  NATL1_02441  two-component response regulator  30.3 
 
 
242 aa  86.7  2e-16  Prochlorococcus marinus str. NATL1A  Bacteria  normal  0.72299  normal 
 
 
-
 
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