More than 300 homologs were found in PanDaTox collection
for query gene Rmet_2950 on replicon NC_007973
Organism: Cupriavidus metallidurans CH34



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_007973  Rmet_2950  response regulator receiver sensor signal transduction histidine kinase  100 
 
 
378 aa  774    Cupriavidus metallidurans CH34  Bacteria  normal  0.37884  normal 
 
 
-
 
NC_007347  Reut_A2813  response regulator receiver sensor signal transduction histidine kinase  80.32 
 
 
377 aa  614  1e-175  Ralstonia eutropha JMP134  Bacteria  normal  0.963287  n/a   
 
 
-
 
NC_007952  Bxe_B2007  response regulator receiver sensor signal transduction histidine kinase  61.02 
 
 
388 aa  456  1e-127  Burkholderia xenovorans LB400  Bacteria  hitchhiker  0.000116465  normal  0.0324755 
 
 
-
 
NC_010676  Bphyt_4751  response regulator receiver sensor signal transduction histidine kinase  61.46 
 
 
384 aa  440  9.999999999999999e-123  Burkholderia phytofirmans PsJN  Bacteria  normal  0.0259995  normal  0.0850645 
 
 
-
 
NC_010682  Rpic_2976  response regulator receiver sensor signal transduction histidine kinase  56.57 
 
 
368 aa  396  1e-109  Ralstonia pickettii 12J  Bacteria  normal  0.598418  normal 
 
 
-
 
NC_012856  Rpic12D_2566  response regulator receiver sensor signal transduction histidine kinase  56.87 
 
 
369 aa  398  1e-109  Ralstonia pickettii 12D  Bacteria  normal  normal  0.236818 
 
 
-
 
NC_003295  RSc2737  two component response regulator transcription regulator protein  55.74 
 
 
374 aa  379  1e-104  Ralstonia solanacearum GMI1000  Bacteria  normal  normal 
 
 
-
 
NC_008781  Pnap_3728  response regulator receiver sensor signal transduction histidine kinase  41.49 
 
 
395 aa  264  1e-69  Polaromonas naphthalenivorans CJ2  Bacteria  normal  0.439666  normal  0.0786529 
 
 
-
 
NC_007952  Bxe_B2691  response regulator receiver domain-containing protein  70 
 
 
134 aa  171  2e-41  Burkholderia xenovorans LB400  Bacteria  normal  normal 
 
 
-
 
NC_010681  Bphyt_1289  response regulator receiver protein  65 
 
 
134 aa  156  5.0000000000000005e-37  Burkholderia phytofirmans PsJN  Bacteria  normal  0.295021  normal  0.0758601 
 
 
-
 
NC_013061  Phep_1525  ATP-binding region ATPase domain protein  23.94 
 
 
359 aa  127  3e-28  Pedobacter heparinus DSM 2366  Bacteria  normal  0.331233  normal  0.636632 
 
 
-
 
NC_007973  Rmet_2949  response regulator receiver domain-containing protein  36.51 
 
 
332 aa  109  9.000000000000001e-23  Cupriavidus metallidurans CH34  Bacteria  normal  normal 
 
 
-
 
NC_007347  Reut_A2812  response regulator receiver  36.9 
 
 
335 aa  108  1e-22  Ralstonia eutropha JMP134  Bacteria  normal  0.101507  n/a   
 
 
-
 
NC_003295  RSc2738  response regulator transcription regulator protein  39.62 
 
 
336 aa  108  2e-22  Ralstonia solanacearum GMI1000  Bacteria  normal  normal 
 
 
-
 
NC_007952  Bxe_B2689  response regulator receiver domain-containing protein  40.85 
 
 
339 aa  107  2e-22  Burkholderia xenovorans LB400  Bacteria  normal  0.579235  normal 
 
 
-
 
NC_012856  Rpic12D_2567  response regulator receiver protein  38.36 
 
 
339 aa  107  4e-22  Ralstonia pickettii 12D  Bacteria  normal  normal  0.342173 
 
 
-
 
NC_010682  Rpic_2977  response regulator receiver protein  38.1 
 
 
339 aa  106  6e-22  Ralstonia pickettii 12J  Bacteria  normal  normal 
 
 
-
 
NC_010681  Bphyt_1291  response regulator receiver protein  38.82 
 
 
336 aa  106  8e-22  Burkholderia phytofirmans PsJN  Bacteria  normal  0.127237  normal  0.0846123 
 
 
-
 
NC_013132  Cpin_1315  response regulator receiver sensor signal transduction histidine kinase  22.37 
 
 
365 aa  99.8  7e-20  Chitinophaga pinensis DSM 2588  Bacteria  normal  normal 
 
 
-
 
NC_008312  Tery_0615  response regulator receiver sensor signal transduction histidine kinase  25.06 
 
 
395 aa  97.1  5e-19  Trichodesmium erythraeum IMS101  Bacteria  normal  hitchhiker  0.00858549 
 
 
-
 
NC_014148  Plim_3060  response regulator receiver  38.71 
 
 
410 aa  94.7  3e-18  Planctomyces limnophilus DSM 3776  Bacteria  normal  n/a   
 
 
-
 
NC_008346  Swol_2547  response regulator receiver protein  36.42 
 
 
395 aa  94  4e-18  Syntrophomonas wolfei subsp. wolfei str. Goettingen  Bacteria  normal  n/a   
 
 
-
 
NC_013037  Dfer_2392  response regulator receiver sensor signal transduction histidine kinase  22.02 
 
 
363 aa  93.6  6e-18  Dyadobacter fermentans DSM 18053  Bacteria  normal  normal 
 
 
-
 
NC_011729  PCC7424_1421  response regulator receiver sensor signal transduction histidine kinase  24.82 
 
 
404 aa  92.4  1e-17  Cyanothece sp. PCC 7424  Bacteria  n/a    normal 
 
 
-
 
NC_008781  Pnap_3729  response regulator receiver protein  41.8 
 
 
323 aa  91.3  3e-17  Polaromonas naphthalenivorans CJ2  Bacteria  normal  0.800159  normal  0.0418103 
 
 
-
 
NC_010814  Glov_3153  response regulator receiver sensor signal transduction histidine kinase  25.2 
 
 
366 aa  91.3  3e-17  Geobacter lovleyi SZ  Bacteria  normal  n/a   
 
 
-
 
NC_011146  Gbem_3634  response regulator receiver sensor signal transduction histidine kinase  23.16 
 
 
379 aa  90.5  4e-17  Geobacter bemidjiensis Bem  Bacteria  normal  0.0261897  n/a   
 
 
-
 
NC_007517  Gmet_3473  response regulator receiver domain-containing protein  36.51 
 
 
823 aa  90.1  5e-17  Geobacter metallireducens GS-15  Bacteria  normal  normal 
 
 
-
 
NC_009483  Gura_0224  response regulator receiver sensor signal transduction histidine kinase  24.94 
 
 
379 aa  89  1e-16  Geobacter uraniireducens Rf4  Bacteria  normal  n/a   
 
 
-
 
NC_007760  Adeh_3383  periplasmic sensor signal transduction histidine kinase  31.98 
 
 
548 aa  88.2  2e-16  Anaeromyxobacter dehalogenans 2CP-C  Bacteria  normal  0.918408  n/a   
 
 
-
 
NC_007908  Rfer_1980  response regulator receiver modulated metal dependent phosphohydrolase  35.03 
 
 
449 aa  87.4  4e-16  Rhodoferax ferrireducens T118  Bacteria  normal  0.247955  n/a   
 
 
-
 
NC_012918  GM21_3739  response regulator receiver sensor signal transduction histidine kinase  23.34 
 
 
379 aa  86.7  6e-16  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_008312  Tery_3155  adenylate/guanylate cyclase  33.77 
 
 
1172 aa  85.9  9e-16  Trichodesmium erythraeum IMS101  Bacteria  normal  0.386213  hitchhiker  0.00095291 
 
 
-
 
NC_002939  GSU0149  sensor histidine kinase/response regulator  25.33 
 
 
371 aa  85.9  0.000000000000001  Geobacter sulfurreducens PCA  Bacteria  normal  n/a   
 
 
-
 
NC_008781  Pnap_3513  integral membrane sensor signal transduction histidine kinase  27.39 
 
 
425 aa  85.9  0.000000000000001  Polaromonas naphthalenivorans CJ2  Bacteria  normal  0.600596  normal 
 
 
-
 
NC_012918  GM21_2551  response regulator receiver sensor signal transduction histidine kinase  22.89 
 
 
396 aa  85.1  0.000000000000002  Geobacter sp. M21  Bacteria  n/a    hitchhiker  1.14529e-19 
 
 
-
 
NC_011146  Gbem_1662  response regulator receiver sensor signal transduction histidine kinase  22.41 
 
 
396 aa  84.3  0.000000000000003  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_007948  Bpro_4046  periplasmic sensor signal transduction histidine kinase  29.46 
 
 
434 aa  82.8  0.000000000000009  Polaromonas sp. JS666  Bacteria  normal  normal  0.421947 
 
 
-
 
NC_002947  PP_2942  response regulator  32.61 
 
 
456 aa  82  0.00000000000001  Pseudomonas putida KT2440  Bacteria  normal  0.714666  normal  0.271158 
 
 
-
 
NC_014248  Aazo_2338  GAF sensor-containing adenylate/guanylate cyclase  35.17 
 
 
1180 aa  82  0.00000000000002  'Nostoc azollae' 0708  Bacteria  normal  0.0263037  n/a   
 
 
-
 
NC_009483  Gura_2017  integral membrane sensor signal transduction histidine kinase  29.3 
 
 
422 aa  81.6  0.00000000000002  Geobacter uraniireducens Rf4  Bacteria  normal  0.224575  n/a   
 
 
-
 
NC_008609  Ppro_3175  response regulator receiver sensor signal transduction histidine kinase  27.37 
 
 
370 aa  81.3  0.00000000000002  Pelobacter propionicus DSM 2379  Bacteria  normal  0.768346  n/a   
 
 
-
 
NC_011145  AnaeK_3466  integral membrane sensor signal transduction histidine kinase  29.39 
 
 
548 aa  81.3  0.00000000000002  Anaeromyxobacter sp. K  Bacteria  normal  0.0535402  n/a   
 
 
-
 
NC_010814  Glov_2289  response regulator receiver protein  33.88 
 
 
135 aa  80.9  0.00000000000003  Geobacter lovleyi SZ  Bacteria  normal  n/a   
 
 
-
 
NC_011312  VSAL_I1157  autoinducer regulatory protein AinR  25.67 
 
 
822 aa  80.9  0.00000000000003  Aliivibrio salmonicida LFI1238  Bacteria  normal  n/a   
 
 
-
 
NC_007492  Pfl01_4555  response regulator receiver Signal transduction histidine kinase  22.9 
 
 
467 aa  81.3  0.00000000000003  Pseudomonas fluorescens Pf0-1  Bacteria  normal  normal 
 
 
-
 
NC_011891  A2cp1_3530  histidine kinase  29.39 
 
 
548 aa  81.3  0.00000000000003  Anaeromyxobacter dehalogenans 2CP-1  Bacteria  normal  n/a   
 
 
-
 
NC_009512  Pput_2745  response regulator receiver protein  32.07 
 
 
456 aa  80.9  0.00000000000004  Pseudomonas putida F1  Bacteria  normal  0.862781  normal 
 
 
-
 
NC_007517  Gmet_3472  response regulator receiver domain-containing protein  35.25 
 
 
187 aa  80.5  0.00000000000004  Geobacter metallireducens GS-15  Bacteria  normal  normal 
 
 
-
 
NC_007973  Rmet_1542  response regulator receiver domain-containing protein  28.22 
 
 
309 aa  80.9  0.00000000000004  Cupriavidus metallidurans CH34  Bacteria  decreased coverage  0.000150385  normal  0.319028 
 
 
-
 
NC_008390  Bamb_1597  response regulator receiver modulated diguanylate cyclase/phosphodiesterase  34.11 
 
 
860 aa  80.5  0.00000000000004  Burkholderia ambifaria AMMD  Bacteria  normal  0.711633  n/a   
 
 
-
 
NC_011769  DvMF_1088  signal transduction histidine kinase, nitrogen specific, NtrB  28.73 
 
 
822 aa  80.1  0.00000000000006  Desulfovibrio vulgaris str. 'Miyazaki F'  Bacteria  n/a    normal  0.436726 
 
 
-
 
NC_007517  Gmet_3477  PAS/PAC sensor hybrid histidine kinase  33.88 
 
 
1465 aa  80.1  0.00000000000006  Geobacter metallireducens GS-15  Bacteria  normal  normal 
 
 
-
 
NC_007952  Bxe_B2690  hypothetical protein  67.74 
 
 
62 aa  80.1  0.00000000000006  Burkholderia xenovorans LB400  Bacteria  normal  0.604414  normal 
 
 
-
 
NC_008043  TM1040_3371  histidine kinase  28.69 
 
 
887 aa  80.1  0.00000000000006  Ruegeria sp. TM1040  Bacteria  normal  normal  0.564838 
 
 
-
 
NC_007413  Ava_2239  adenylate/guanylate cyclase  34.48 
 
 
1156 aa  79.7  0.00000000000007  Anabaena variabilis ATCC 29413  Bacteria  normal  0.159061  normal 
 
 
-
 
NC_007517  Gmet_2677  response regulator receiver sensor signal transduction histidine kinase  24.33 
 
 
395 aa  79.7  0.00000000000007  Geobacter metallireducens GS-15  Bacteria  normal  0.971959  normal  0.344308 
 
 
-
 
NC_010571  Oter_2708  response regulator receiver protein  36.44 
 
 
141 aa  79.7  0.00000000000008  Opitutus terrae PB90-1  Bacteria  normal  0.0523429  normal 
 
 
-
 
NC_012918  GM21_2364  response regulator receiver protein  36.22 
 
 
806 aa  79.3  0.00000000000009  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_010814  Glov_1745  response regulator receiver sensor signal transduction histidine kinase  22.31 
 
 
417 aa  79.3  0.00000000000009  Geobacter lovleyi SZ  Bacteria  normal  0.0330192  n/a   
 
 
-
 
NC_013440  Hoch_0050  two component, sigma54 specific, transcriptional regulator, Fis family  35.22 
 
 
515 aa  79.3  0.00000000000009  Haliangium ochraceum DSM 14365  Bacteria  normal  normal  0.0532507 
 
 
-
 
NC_009523  RoseRS_0231  GAF sensor hybrid histidine kinase  27.31 
 
 
844 aa  79.7  0.00000000000009  Roseiflexus sp. RS-1  Bacteria  normal  0.794534  normal  0.63544 
 
 
-
 
NC_014212  Mesil_0932  multi-sensor signal transduction histidine kinase  28.88 
 
 
827 aa  79.3  0.0000000000001  Meiothermus silvanus DSM 9946  Bacteria  normal  normal  0.202098 
 
 
-
 
NC_007517  Gmet_0696  histidine kinase  28.15 
 
 
248 aa  79.3  0.0000000000001  Geobacter metallireducens GS-15  Bacteria  hitchhiker  0.0073771  normal 
 
 
-
 
NC_008825  Mpe_A2447  signal transduction protein  35.03 
 
 
965 aa  79.3  0.0000000000001  Methylibium petroleiphilum PM1  Bacteria  normal  0.936876  normal 
 
 
-
 
NC_008751  Dvul_0403  response regulator receiver sensor signal transduction histidine kinase  27.59 
 
 
374 aa  79.3  0.0000000000001  Desulfovibrio vulgaris DP4  Bacteria  normal  normal  0.150899 
 
 
-
 
NC_010581  Bind_1884  response regulator receiver sensor signal transduction histidine kinase  25 
 
 
389 aa  78.2  0.0000000000002  Beijerinckia indica subsp. indica ATCC 9039  Bacteria  normal  0.329348  normal 
 
 
-
 
NC_010505  Mrad2831_5226  response regulator receiver sensor signal transduction histidine kinase  25.92 
 
 
388 aa  78.6  0.0000000000002  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  normal 
 
 
-
 
NC_009483  Gura_0737  integral membrane sensor signal transduction histidine kinase  26.01 
 
 
644 aa  78.2  0.0000000000002  Geobacter uraniireducens Rf4  Bacteria  hitchhiker  0.00181069  n/a   
 
 
-
 
NC_008228  Patl_4152  histidine kinase  24.35 
 
 
662 aa  78.2  0.0000000000002  Pseudoalteromonas atlantica T6c  Bacteria  normal  n/a   
 
 
-
 
NC_011060  Ppha_1021  putative PAS/PAC sensor protein  31.11 
 
 
564 aa  77.8  0.0000000000003  Pelodictyon phaeoclathratiforme BU-1  Bacteria  normal  n/a   
 
 
-
 
NC_009675  Anae109_2440  response regulator receiver sensor signal transduction histidine kinase  27.95 
 
 
375 aa  77.8  0.0000000000003  Anaeromyxobacter sp. Fw109-5  Bacteria  normal  0.467167  normal  0.627522 
 
 
-
 
NC_009637  MmarC7_0372  integral membrane sensor signal transduction histidine kinase  24.9 
 
 
614 aa  77.8  0.0000000000003  Methanococcus maripaludis C7  Archaea  normal  0.899415  normal  0.0476359 
 
 
-
 
NC_008752  Aave_3093  integral membrane sensor signal transduction histidine kinase  28.4 
 
 
595 aa  77.8  0.0000000000003  Acidovorax citrulli AAC00-1  Bacteria  hitchhiker  0.00296366  normal  0.187641 
 
 
-
 
NC_007517  Gmet_0202  response regulator receiver sensor signal transduction histidine kinase  23.78 
 
 
374 aa  77.8  0.0000000000003  Geobacter metallireducens GS-15  Bacteria  normal  hitchhiker  0.00101669 
 
 
-
 
NC_013132  Cpin_1404  response regulator receiver protein  31.69 
 
 
154 aa  77.4  0.0000000000003  Chitinophaga pinensis DSM 2588  Bacteria  normal  normal 
 
 
-
 
NC_008463  PA14_26830  putative two-component response regulator  37.61 
 
 
303 aa  77.8  0.0000000000003  Pseudomonas aeruginosa UCBPP-PA14  Bacteria  normal  normal 
 
 
-
 
NC_013132  Cpin_2257  GAF sensor hybrid histidine kinase  29.13 
 
 
1162 aa  77.4  0.0000000000004  Chitinophaga pinensis DSM 2588  Bacteria  normal  normal 
 
 
-
 
NC_011769  DvMF_1131  response regulator receiver sensor signal transduction histidine kinase  23.9 
 
 
500 aa  77.4  0.0000000000004  Desulfovibrio vulgaris str. 'Miyazaki F'  Bacteria  n/a    normal 
 
 
-
 
NC_014248  Aazo_4317  response regulator receiver modulated GAF sensor protein  29.01 
 
 
317 aa  77.4  0.0000000000004  'Nostoc azollae' 0708  Bacteria  normal  0.248315  n/a   
 
 
-
 
NC_011662  Tmz1t_3193  PAS/PAC sensor signal transduction histidine kinase  28.94 
 
 
902 aa  77  0.0000000000005  Thauera sp. MZ1T  Bacteria  normal  0.0583373  n/a   
 
 
-
 
NC_007298  Daro_3962  two component, sigma54 specific, Fis family transcriptional regulator  35.66 
 
 
495 aa  77  0.0000000000005  Dechloromonas aromatica RCB  Bacteria  normal  normal 
 
 
-
 
NC_010510  Mrad2831_6179  response regulator receiver sensor signal transduction histidine kinase  25.75 
 
 
389 aa  77  0.0000000000005  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  normal  0.271486 
 
 
-
 
NC_009135  MmarC5_0464  integral membrane sensor signal transduction histidine kinase  23.48 
 
 
614 aa  76.3  0.0000000000007  Methanococcus maripaludis C5  Archaea  normal  0.778528  n/a   
 
 
-
 
NC_010581  Bind_1161  two component, sigma54 specific, Fis family transcriptional regulator  40.2 
 
 
496 aa  76.3  0.0000000000007  Beijerinckia indica subsp. indica ATCC 9039  Bacteria  normal  0.175427  normal 
 
 
-
 
NC_012918  GM21_2368  putative PAS/PAC sensor protein  31.54 
 
 
270 aa  76.3  0.0000000000007  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_007519  Dde_0696  periplasmic sensor signal transduction histidine kinase  26.92 
 
 
570 aa  76.6  0.0000000000007  Desulfovibrio desulfuricans subsp. desulfuricans str. G20  Bacteria  normal  n/a   
 
 
-
 
NC_010681  Bphyt_1290  putative CheA signal transduction histidine kinase  70.18 
 
 
62 aa  76.6  0.0000000000007  Burkholderia phytofirmans PsJN  Bacteria  normal  0.294116  normal  0.0703987 
 
 
-
 
NC_009975  MmarC6_1547  integral membrane sensor signal transduction histidine kinase  25.86 
 
 
613 aa  76.6  0.0000000000007  Methanococcus maripaludis C6  Archaea  normal  n/a   
 
 
-
 
NC_010676  Bphyt_6245  integral membrane sensor hybrid histidine kinase  31.08 
 
 
857 aa  76.3  0.0000000000008  Burkholderia phytofirmans PsJN  Bacteria  normal  normal 
 
 
-
 
NC_008609  Ppro_2723  putative PAS/PAC sensor protein  31.76 
 
 
285 aa  76.3  0.0000000000009  Pelobacter propionicus DSM 2379  Bacteria  normal  n/a   
 
 
-
 
NC_008255  CHU_2793  two-component response regulator  26.49 
 
 
154 aa  76.3  0.0000000000009  Cytophaga hutchinsonii ATCC 33406  Bacteria  normal  normal  0.0292911 
 
 
-
 
NC_013205  Aaci_0515  PAS/PAC sensor signal transduction histidine kinase  30.08 
 
 
533 aa  75.9  0.000000000001  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  n/a   
 
 
-
 
NC_007492  Pfl01_4550  response regulator receiver domain-containing protein  33.33 
 
 
451 aa  75.5  0.000000000001  Pseudomonas fluorescens Pf0-1  Bacteria  normal  0.01769  normal 
 
 
-
 
NC_007498  Pcar_2015  two component hybrid sensor response regulator  23.83 
 
 
391 aa  75.5  0.000000000001  Pelobacter carbinolicus DSM 2380  Bacteria  normal  n/a   
 
 
-
 
NC_013440  Hoch_5165  response regulator receiver sensor hybrid histidine kinase  26.02 
 
 
593 aa  75.9  0.000000000001  Haliangium ochraceum DSM 14365  Bacteria  normal  normal 
 
 
-
 
NC_007760  Adeh_1277  periplasmic sensor signal transduction histidine kinase  31.2 
 
 
630 aa  75.9  0.000000000001  Anaeromyxobacter dehalogenans 2CP-C  Bacteria  normal  0.449456  n/a   
 
 
-
 
NC_007952  Bxe_B2006  periplasmic sensor hybrid histidine kinase  25.56 
 
 
852 aa  75.5  0.000000000001  Burkholderia xenovorans LB400  Bacteria  hitchhiker  0.000507491  normal  0.0782006 
 
 
-
 
NC_013223  Dret_0969  histidine kinase  28.28 
 
 
801 aa  75.5  0.000000000001  Desulfohalobium retbaense DSM 5692  Bacteria  hitchhiker  0.0000115814  hitchhiker  0.0000040144 
 
 
-
 
NC_010551  BamMC406_1617  response regulator receiver modulated diguanylate cyclase/phosphodiesterase  35.66 
 
 
860 aa  76.3  0.000000000001  Burkholderia ambifaria MC40-6  Bacteria  normal  normal 
 
 
-
 
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