More than 300 homologs were found in PanDaTox collection
for query gene Rmar_2518 on replicon NC_013501
Organism: Rhodothermus marinus DSM 4252



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_013501  Rmar_2518  response regulator receiver protein  100 
 
 
519 aa  1058    Rhodothermus marinus DSM 4252  Bacteria  normal  0.487815  n/a   
 
 
-
 
NC_013037  Dfer_5047  response regulator receiver protein  47.01 
 
 
521 aa  520  1e-146  Dyadobacter fermentans DSM 18053  Bacteria  normal  normal 
 
 
-
 
NC_013061  Phep_4282  PglZ domain protein  47.06 
 
 
518 aa  513  1e-144  Pedobacter heparinus DSM 2366  Bacteria  normal  0.769544  normal 
 
 
-
 
NC_009441  Fjoh_2906  response regulator receiver protein  44.51 
 
 
517 aa  486  1e-136  Flavobacterium johnsoniae UW101  Bacteria  normal  0.568683  n/a   
 
 
-
 
NC_013730  Slin_3042  response regulator receiver protein  45.77 
 
 
524 aa  479  1e-134  Spirosoma linguale DSM 74  Bacteria  normal  normal  0.0742856 
 
 
-
 
NC_002950  PG0928  response regulator  45.7 
 
 
518 aa  476  1e-133  Porphyromonas gingivalis W83  Bacteria  n/a    normal  0.581359 
 
 
-
 
NC_008255  CHU_1040  two-component response regulator  41.51 
 
 
518 aa  476  1e-133  Cytophaga hutchinsonii ATCC 33406  Bacteria  normal  0.429651  normal 
 
 
-
 
NC_013132  Cpin_1282  response regulator receiver protein  43.13 
 
 
517 aa  471  1.0000000000000001e-131  Chitinophaga pinensis DSM 2588  Bacteria  hitchhiker  0.00300616  normal 
 
 
-
 
NC_014230  CA2559_08151  response regulator  41.95 
 
 
516 aa  450  1e-125  Croceibacter atlanticus HTCC2559  Bacteria  normal  n/a   
 
 
-
 
NC_002939  GSU2693  response regulator  42.34 
 
 
128 aa  87  8e-16  Geobacter sulfurreducens PCA  Bacteria  normal  n/a   
 
 
-
 
NC_008740  Maqu_2223  response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)  35.07 
 
 
725 aa  85.9  0.000000000000001  Marinobacter aquaeolei VT8  Bacteria  normal  0.847933  n/a   
 
 
-
 
NC_012918  GM21_2942  two component transcriptional regulator, winged helix family  34.85 
 
 
234 aa  84.7  0.000000000000004  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_012918  GM21_0009  multi-sensor signal transduction histidine kinase  30.84 
 
 
509 aa  84.7  0.000000000000004  Geobacter sp. M21  Bacteria  n/a    normal  0.923259 
 
 
-
 
NC_009483  Gura_1334  two component transcriptional regulator  36.36 
 
 
243 aa  83.6  0.000000000000007  Geobacter uraniireducens Rf4  Bacteria  normal  0.592557  n/a   
 
 
-
 
NC_009483  Gura_3647  two component, sigma-54 specific, Fis family transcriptional regulator  33.61 
 
 
471 aa  83.6  0.000000000000008  Geobacter uraniireducens Rf4  Bacteria  normal  0.0209004  n/a   
 
 
-
 
NC_011146  Gbem_1342  two component transcriptional regulator, winged helix family  34.85 
 
 
234 aa  83.2  0.000000000000009  Geobacter bemidjiensis Bem  Bacteria  normal  0.0144629  n/a   
 
 
-
 
NC_011146  Gbem_0010  multi-sensor signal transduction histidine kinase  31.28 
 
 
511 aa  82.8  0.00000000000001  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_011146  Gbem_1522  two component, sigma54 specific, transcriptional regulator, Fis family  36.8 
 
 
461 aa  82  0.00000000000003  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_007517  Gmet_0010  PAS/PAC sensor hybrid histidine kinase  34.03 
 
 
508 aa  81.3  0.00000000000004  Geobacter metallireducens GS-15  Bacteria  normal  0.0502065  normal 
 
 
-
 
NC_012918  GM21_2694  two component, sigma54 specific, transcriptional regulator, Fis family  36 
 
 
461 aa  81.3  0.00000000000004  Geobacter sp. M21  Bacteria  n/a    hitchhiker  7.62039e-17 
 
 
-
 
NC_008554  Sfum_2806  two component, sigma54 specific, Fis family transcriptional regulator  34.88 
 
 
450 aa  81.3  0.00000000000004  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  normal 
 
 
-
 
NC_008576  Mmc1_3443  response regulator receiver protein  31.69 
 
 
223 aa  80.9  0.00000000000005  Magnetococcus sp. MC-1  Bacteria  normal  normal 
 
 
-
 
NC_008228  Patl_1603  two component, sigma54 specific, Fis family transcriptional regulator  39.45 
 
 
449 aa  80.5  0.00000000000007  Pseudoalteromonas atlantica T6c  Bacteria  normal  n/a   
 
 
-
 
NC_009972  Haur_1267  response regulator receiver sensor signal transduction histidine kinase  30.25 
 
 
542 aa  80.1  0.00000000000008  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  n/a   
 
 
-
 
NC_008554  Sfum_3765  two component, sigma54 specific, Fis family transcriptional regulator  37.6 
 
 
463 aa  79.7  0.0000000000001  Syntrophobacter fumaroxidans MPOB  Bacteria  decreased coverage  0.000821276  normal 
 
 
-
 
NC_011769  DvMF_1988  response regulator receiver protein  41.28 
 
 
119 aa  79.3  0.0000000000002  Desulfovibrio vulgaris str. 'Miyazaki F'  Bacteria  n/a    normal 
 
 
-
 
NC_008609  Ppro_0507  two component transcriptional regulator  33.33 
 
 
236 aa  78.6  0.0000000000003  Pelobacter propionicus DSM 2379  Bacteria  normal  n/a   
 
 
-
 
NC_013173  Dbac_2037  response regulator receiver protein  34.17 
 
 
120 aa  77.8  0.0000000000004  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  n/a   
 
 
-
 
NC_013223  Dret_0097  two component, sigma54 specific, transcriptional regulator, Fis family  32.56 
 
 
448 aa  77.8  0.0000000000004  Desulfohalobium retbaense DSM 5692  Bacteria  normal  normal 
 
 
-
 
NC_009523  RoseRS_0338  response regulator receiver modulated metal dependent phosphohydrolase  33.11 
 
 
513 aa  78.2  0.0000000000004  Roseiflexus sp. RS-1  Bacteria  normal  normal  0.102838 
 
 
-
 
NC_010814  Glov_1694  two component, sigma54 specific, transcriptional regulator, Fis family  33.61 
 
 
472 aa  77.8  0.0000000000004  Geobacter lovleyi SZ  Bacteria  normal  n/a   
 
 
-
 
NC_012918  GM21_0684  two component, sigma54 specific, transcriptional regulator, Fis family  33.61 
 
 
469 aa  77.8  0.0000000000005  Geobacter sp. M21  Bacteria  n/a    hitchhiker  0.0000000000150794 
 
 
-
 
NC_008554  Sfum_1934  two component, sigma54 specific, Fis family transcriptional regulator  34.65 
 
 
476 aa  77.8  0.0000000000005  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  0.808753  normal  0.132653 
 
 
-
 
NC_002939  GSU0598  sigma-54 dependent DNA-binding response regulator  33.06 
 
 
470 aa  77.4  0.0000000000006  Geobacter sulfurreducens PCA  Bacteria  normal  0.885444  n/a   
 
 
-
 
NC_007517  Gmet_2924  two component, sigma54 specific, Fis family transcriptional regulator  32.26 
 
 
470 aa  77  0.0000000000007  Geobacter metallireducens GS-15  Bacteria  normal  0.777319  hitchhiker  0.0000000000564278 
 
 
-
 
NC_007517  Gmet_0702  two component, sigma54 specific, Fis family transcriptional regulator  36.72 
 
 
460 aa  77  0.0000000000008  Geobacter metallireducens GS-15  Bacteria  normal  normal 
 
 
-
 
NC_002939  GSU1879  DNA-binding response regulator  32.58 
 
 
238 aa  76.6  0.0000000000009  Geobacter sulfurreducens PCA  Bacteria  decreased coverage  0.000557668  n/a   
 
 
-
 
NC_010814  Glov_3569  two component transcriptional regulator, winged helix family  33.33 
 
 
235 aa  76.6  0.0000000000009  Geobacter lovleyi SZ  Bacteria  normal  n/a   
 
 
-
 
NC_011145  AnaeK_0113  two component, sigma54 specific, transcriptional regulator, Fis family  33.33 
 
 
459 aa  76.6  0.0000000000009  Anaeromyxobacter sp. K  Bacteria  normal  0.212971  n/a   
 
 
-
 
NC_011898  Ccel_1982  two component transcriptional regulator, AraC family  32.35 
 
 
544 aa  76.6  0.000000000001  Clostridium cellulolyticum H10  Bacteria  normal  0.184696  n/a   
 
 
-
 
NC_007517  Gmet_1291  two component transcriptional regulator  32.58 
 
 
240 aa  75.5  0.000000000002  Geobacter metallireducens GS-15  Bacteria  hitchhiker  0.0000572556  hitchhiker  0.0000375019 
 
 
-
 
NC_011769  DvMF_1544  response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)  34.78 
 
 
739 aa  75.5  0.000000000002  Desulfovibrio vulgaris str. 'Miyazaki F'  Bacteria  n/a    normal  0.498595 
 
 
-
 
NC_007908  Rfer_2741  two component, sigma54 specific, Fis family transcriptional regulator  34.68 
 
 
474 aa  75.5  0.000000000002  Rhodoferax ferrireducens T118  Bacteria  normal  0.0363909  n/a   
 
 
-
 
NC_012918  GM21_2828  two component, sigma54 specific, transcriptional regulator, Fis family  40.2 
 
 
444 aa  75.1  0.000000000003  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_011145  AnaeK_0673  two component, sigma54 specific, transcriptional regulator, Fis family  33.07 
 
 
457 aa  75.1  0.000000000003  Anaeromyxobacter sp. K  Bacteria  normal  n/a   
 
 
-
 
NC_011891  A2cp1_0673  two component, sigma54 specific, transcriptional regulator, Fis family  33.07 
 
 
458 aa  75.1  0.000000000003  Anaeromyxobacter dehalogenans 2CP-1  Bacteria  normal  n/a   
 
 
-
 
NC_013132  Cpin_0673  two component transcriptional regulator, winged helix family  31.79 
 
 
235 aa  75.1  0.000000000003  Chitinophaga pinensis DSM 2588  Bacteria  normal  0.996485  normal 
 
 
-
 
NC_007760  Adeh_0639  two component, sigma54 specific, Fis family transcriptional regulator  33.33 
 
 
455 aa  75.1  0.000000000003  Anaeromyxobacter dehalogenans 2CP-C  Bacteria  normal  n/a   
 
 
-
 
NC_008554  Sfum_3268  two component, sigma54 specific, Fis family transcriptional regulator  36.51 
 
 
483 aa  75.1  0.000000000003  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  0.474695  normal 
 
 
-
 
NC_011138  MADE_01723  two-component system response regulator  34.71 
 
 
446 aa  74.7  0.000000000004  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  n/a   
 
 
-
 
NC_002939  GSU0963  sigma-54 dependent DNA-binding response regulator  36.36 
 
 
467 aa  74.7  0.000000000004  Geobacter sulfurreducens PCA  Bacteria  normal  n/a   
 
 
-
 
NC_002939  GSU1658  response regulator/GGDEF domain-containing protein  33.06 
 
 
458 aa  74.7  0.000000000004  Geobacter sulfurreducens PCA  Bacteria  normal  0.939598  n/a   
 
 
-
 
NC_002939  GSU2915  sigma-54 dependent DNA-binding response regulator  37.3 
 
 
457 aa  74.7  0.000000000004  Geobacter sulfurreducens PCA  Bacteria  normal  n/a   
 
 
-
 
NC_011891  A2cp1_0124  two component, sigma54 specific, transcriptional regulator, Fis family  32.65 
 
 
459 aa  74.7  0.000000000004  Anaeromyxobacter dehalogenans 2CP-1  Bacteria  normal  0.99079  n/a   
 
 
-
 
NC_007760  Adeh_0106  two component, sigma54 specific, Fis family transcriptional regulator  32.65 
 
 
459 aa  74.3  0.000000000004  Anaeromyxobacter dehalogenans 2CP-C  Bacteria  normal  0.327572  n/a   
 
 
-
 
NC_009943  Dole_2739  two component, sigma54 specific, Fis family transcriptional regulator  32 
 
 
451 aa  74.7  0.000000000004  Desulfococcus oleovorans Hxd3  Bacteria  normal  0.693002  n/a   
 
 
-
 
NC_007908  Rfer_2735  response regulator receiver domain-containing protein  39.42 
 
 
242 aa  74.3  0.000000000004  Rhodoferax ferrireducens T118  Bacteria  normal  0.284606  n/a   
 
 
-
 
NC_010814  Glov_2633  two component, sigma54 specific, transcriptional regulator, Fis family  30.85 
 
 
467 aa  74.7  0.000000000004  Geobacter lovleyi SZ  Bacteria  normal  n/a   
 
 
-
 
NC_010814  Glov_2786  two component, sigma54 specific, transcriptional regulator, Fis family  41.35 
 
 
480 aa  74.3  0.000000000004  Geobacter lovleyi SZ  Bacteria  normal  0.543097  n/a   
 
 
-
 
NC_008699  Noca_1748  response regulator receiver  35.04 
 
 
123 aa  74.3  0.000000000004  Nocardioides sp. JS614  Bacteria  normal  0.122601  n/a   
 
 
-
 
NC_009483  Gura_0495  two component, sigma-54 specific, Fis family transcriptional regulator  35.94 
 
 
456 aa  74.3  0.000000000005  Geobacter uraniireducens Rf4  Bacteria  normal  n/a   
 
 
-
 
NC_011145  AnaeK_1869  two component, sigma54 specific, transcriptional regulator, Fis family  33.33 
 
 
464 aa  73.9  0.000000000006  Anaeromyxobacter sp. K  Bacteria  normal  n/a   
 
 
-
 
NC_011725  BCB4264_A3169  regulatory protein VanR  29.32 
 
 
229 aa  73.9  0.000000000006  Bacillus cereus B4264  Bacteria  normal  0.16404  n/a   
 
 
-
 
NC_007517  Gmet_0555  two component, sigma54 specific, Fis family transcriptional regulator  37.3 
 
 
457 aa  73.9  0.000000000006  Geobacter metallireducens GS-15  Bacteria  normal  normal 
 
 
-
 
NC_011146  Gbem_1426  two component, sigma54 specific, transcriptional regulator, Fis family  40.2 
 
 
444 aa  73.9  0.000000000006  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_013165  Shel_11290  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  30.48 
 
 
234 aa  73.9  0.000000000006  Slackia heliotrinireducens DSM 20476  Bacteria  normal  normal 
 
 
-
 
NC_011891  A2cp1_1954  two component, sigma54 specific, transcriptional regulator, Fis family  33.33 
 
 
464 aa  73.9  0.000000000007  Anaeromyxobacter dehalogenans 2CP-1  Bacteria  normal  0.611403  n/a   
 
 
-
 
NC_007404  Tbd_0085  response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)  32.03 
 
 
738 aa  73.9  0.000000000007  Thiobacillus denitrificans ATCC 25259  Bacteria  normal  normal  0.127866 
 
 
-
 
NC_011769  DvMF_2550  multi-sensor signal transduction histidine kinase  34.17 
 
 
685 aa  73.6  0.000000000008  Desulfovibrio vulgaris str. 'Miyazaki F'  Bacteria  n/a    normal 
 
 
-
 
NC_010814  Glov_3521  two component, sigma54 specific, transcriptional regulator, Fis family  28.83 
 
 
440 aa  73.2  0.00000000001  Geobacter lovleyi SZ  Bacteria  normal  n/a   
 
 
-
 
NC_011146  Gbem_0671  two component, sigma54 specific, transcriptional regulator, Fis family  31.09 
 
 
469 aa  73.2  0.00000000001  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_009483  Gura_1428  two component, sigma-54 specific, Fis family transcriptional regulator  36.29 
 
 
460 aa  73.2  0.00000000001  Geobacter uraniireducens Rf4  Bacteria  normal  n/a   
 
 
-
 
NC_011663  Sbal223_1467  response regulator receiver protein  41.86 
 
 
367 aa  73.2  0.00000000001  Shewanella baltica OS223  Bacteria  normal  0.0140274  normal 
 
 
-
 
NC_011083  SeHA_C4505  transcriptional regulatory protein ZraR  32.39 
 
 
441 aa  72.8  0.00000000001  Salmonella enterica subsp. enterica serovar Heidelberg str. SL476  Bacteria  normal  normal  0.11324 
 
 
-
 
NC_009665  Shew185_2906  response regulator receiver protein  41.86 
 
 
367 aa  73.2  0.00000000001  Shewanella baltica OS185  Bacteria  normal  0.0132666  n/a   
 
 
-
 
NC_009943  Dole_2807  two component, sigma54 specific, Fis family transcriptional regulator  34.85 
 
 
466 aa  73.2  0.00000000001  Desulfococcus oleovorans Hxd3  Bacteria  normal  0.75933  n/a   
 
 
-
 
NC_013235  Namu_2566  two component transcriptional regulator, winged helix family  32.43 
 
 
229 aa  73.2  0.00000000001  Nakamurella multipartita DSM 44233  Bacteria  hitchhiker  0.000356007  hitchhiker  0.00345607 
 
 
-
 
NC_007498  Pcar_0768  two component signal transduction response regulator  32.64 
 
 
236 aa  72.8  0.00000000001  Pelobacter carbinolicus DSM 2380  Bacteria  hitchhiker  0.00000000566504  n/a   
 
 
-
 
NC_009052  Sbal_2896  response regulator receiver protein  41.86 
 
 
367 aa  73.2  0.00000000001  Shewanella baltica OS155  Bacteria  hitchhiker  0.00201335  n/a   
 
 
-
 
NC_011369  Rleg2_3169  two component, sigma54 specific, transcriptional regulator, Fis family  27.17 
 
 
444 aa  73.2  0.00000000001  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  0.254755  normal  0.187976 
 
 
-
 
NC_011831  Cagg_2217  two component transcriptional regulator, winged helix family  32.88 
 
 
276 aa  72.8  0.00000000001  Chloroflexus aggregans DSM 9485  Bacteria  hitchhiker  0.00294817  normal 
 
 
-
 
NC_007519  Dde_0533  histidine kinase  37.5 
 
 
244 aa  73.2  0.00000000001  Desulfovibrio desulfuricans subsp. desulfuricans str. G20  Bacteria  normal  n/a   
 
 
-
 
NC_011094  SeSA_A4385  transcriptional regulatory protein ZraR  32.39 
 
 
441 aa  73.2  0.00000000001  Salmonella enterica subsp. enterica serovar Schwarzengrund str. CVM19633  Bacteria  normal  normal  0.712665 
 
 
-
 
NC_007760  Adeh_0417  two component, sigma54 specific, Fis family transcriptional regulator  31.5 
 
 
474 aa  73.2  0.00000000001  Anaeromyxobacter dehalogenans 2CP-C  Bacteria  normal  0.45134  n/a   
 
 
-
 
NC_007760  Adeh_2009  two component, sigma54 specific, Fis family transcriptional regulator  32.59 
 
 
463 aa  72.8  0.00000000001  Anaeromyxobacter dehalogenans 2CP-C  Bacteria  normal  n/a   
 
 
-
 
NC_009943  Dole_2331  response regulator receiver protein  35.11 
 
 
142 aa  73.2  0.00000000001  Desulfococcus oleovorans Hxd3  Bacteria  hitchhiker  0.00000000425244  n/a   
 
 
-
 
NC_011145  AnaeK_0445  two component, sigma54 specific, transcriptional regulator, Fis family  31.5 
 
 
481 aa  73.2  0.00000000001  Anaeromyxobacter sp. K  Bacteria  normal  n/a   
 
 
-
 
NC_009997  Sbal195_3038  response regulator receiver protein  40.7 
 
 
367 aa  72.8  0.00000000001  Shewanella baltica OS195  Bacteria  normal  0.0232368  normal 
 
 
-
 
NC_009441  Fjoh_3924  response regulator receiver protein  29.91 
 
 
121 aa  73.2  0.00000000001  Flavobacterium johnsoniae UW101  Bacteria  normal  0.405001  n/a   
 
 
-
 
NC_009901  Spea_3601  response regulator receiver protein  28.23 
 
 
224 aa  73.2  0.00000000001  Shewanella pealeana ATCC 700345  Bacteria  normal  n/a   
 
 
-
 
NC_011205  SeD_A4581  transcriptional regulatory protein ZraR  32.39 
 
 
441 aa  72.8  0.00000000001  Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853  Bacteria  normal  normal 
 
 
-
 
NC_009943  Dole_1350  response regulator receiver protein  32.03 
 
 
147 aa  72.8  0.00000000001  Desulfococcus oleovorans Hxd3  Bacteria  hitchhiker  0.00189482  n/a   
 
 
-
 
NC_010001  Cphy_0618  two component AraC family transcriptional regulator  35 
 
 
258 aa  73.2  0.00000000001  Clostridium phytofermentans ISDg  Bacteria  decreased coverage  0.00000605397  n/a   
 
 
-
 
NC_010184  BcerKBAB4_0499  two component transcriptional regulator  31.93 
 
 
223 aa  73.2  0.00000000001  Bacillus weihenstephanensis KBAB4  Bacteria  normal  n/a   
 
 
-
 
NC_010814  Glov_2245  two component, sigma54 specific, transcriptional regulator, Fis family  30.43 
 
 
460 aa  72.8  0.00000000001  Geobacter lovleyi SZ  Bacteria  normal  n/a   
 
 
-
 
NC_008751  Dvul_2720  multi-sensor signal transduction histidine kinase  31.25 
 
 
657 aa  73.2  0.00000000001  Desulfovibrio vulgaris DP4  Bacteria  normal  normal  0.312815 
 
 
-
 
NC_011138  MADE_01227  two-component hybrid sensor and regulator  36.13 
 
 
699 aa  72.8  0.00000000001  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  n/a   
 
 
-
 
NC_011729  PCC7424_1976  multi-sensor signal transduction histidine kinase  32.84 
 
 
1383 aa  72  0.00000000002  Cyanothece sp. PCC 7424  Bacteria  n/a    normal  0.624185 
 
 
-
 
NC_011831  Cagg_2051  two component transcriptional regulator, winged helix family  34.78 
 
 
247 aa  72.8  0.00000000002  Chloroflexus aggregans DSM 9485  Bacteria  normal  0.520505  normal 
 
 
-
 
NC_007760  Adeh_0411  two component transcriptional regulator  31.62 
 
 
230 aa  72.4  0.00000000002  Anaeromyxobacter dehalogenans 2CP-C  Bacteria  normal  n/a   
 
 
-
 
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