More than 300 homologs were found in PanDaTox collection
for query gene Nther_0916 on replicon NC_010718
Organism: Natranaerobius thermophilus JW/NM-WN-LF



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_010718  Nther_0916  two component transcriptional regulator, winged helix family  100 
 
 
234 aa  474  1e-133  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  0.0276045  hitchhiker  9.727110000000001e-18 
 
 
-
 
NC_013170  Ccur_11690  response regulator with CheY-like receiver domain protein and winged-helix DNA-binding domain protein  47.83 
 
 
236 aa  228  6e-59  Cryptobacterium curtum DSM 15641  Bacteria  normal  0.52451  normal 
 
 
-
 
NC_013165  Shel_00330  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  48.71 
 
 
240 aa  228  8e-59  Slackia heliotrinireducens DSM 20476  Bacteria  decreased coverage  0.00972196  normal 
 
 
-
 
NC_013204  Elen_0258  two component transcriptional regulator, winged helix family  48.66 
 
 
236 aa  224  1e-57  Eggerthella lenta DSM 2243  Bacteria  normal  0.606292  normal 
 
 
-
 
NC_011898  Ccel_1714  two component transcriptional regulator, winged helix family  49.33 
 
 
234 aa  224  1e-57  Clostridium cellulolyticum H10  Bacteria  normal  0.233786  n/a   
 
 
-
 
NC_010320  Teth514_1155  two component transcriptional regulator  46.19 
 
 
231 aa  219  1.9999999999999999e-56  Thermoanaerobacter sp. X514  Bacteria  decreased coverage  0.000000430064  n/a   
 
 
-
 
NC_010320  Teth514_0766  two component transcriptional regulator  45.74 
 
 
231 aa  217  1e-55  Thermoanaerobacter sp. X514  Bacteria  normal  0.585906  n/a   
 
 
-
 
NC_009972  Haur_0804  two component transcriptional regulator  43.3 
 
 
236 aa  216  2e-55  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  0.324741  n/a   
 
 
-
 
NC_002939  GSU2145  DNA-binding response regulator  43.95 
 
 
232 aa  215  5.9999999999999996e-55  Geobacter sulfurreducens PCA  Bacteria  normal  n/a   
 
 
-
 
NC_013203  Apar_1349  two component transcriptional regulator, winged helix family  45.95 
 
 
237 aa  213  2.9999999999999995e-54  Atopobium parvulum DSM 20469  Bacteria  normal  normal  0.421984 
 
 
-
 
NC_011830  Dhaf_1367  two component transcriptional regulator, winged helix family  47.3 
 
 
230 aa  211  5.999999999999999e-54  Desulfitobacterium hafniense DCB-2  Bacteria  hitchhiker  0.000000177207  n/a   
 
 
-
 
NC_009767  Rcas_0960  two component transcriptional regulator  45.09 
 
 
236 aa  209  2e-53  Roseiflexus castenholzii DSM 13941  Bacteria  normal  normal  0.0214647 
 
 
-
 
NC_009523  RoseRS_3485  two component transcriptional regulator  45.09 
 
 
236 aa  209  2e-53  Roseiflexus sp. RS-1  Bacteria  normal  normal 
 
 
-
 
NC_013205  Aaci_1104  two component transcriptional regulator, winged helix family  43.11 
 
 
233 aa  207  8e-53  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  n/a   
 
 
-
 
NC_011831  Cagg_1100  two component transcriptional regulator, winged helix family  44.84 
 
 
236 aa  207  1e-52  Chloroflexus aggregans DSM 9485  Bacteria  normal  unclonable  0.0000000182155 
 
 
-
 
NC_002936  DET1058  DNA-binding response regulator  45.95 
 
 
227 aa  206  2e-52  Dehalococcoides ethenogenes 195  Bacteria  decreased coverage  0.000187393  n/a   
 
 
-
 
NC_011830  Dhaf_2286  two component transcriptional regulator, winged helix family  43.56 
 
 
231 aa  206  3e-52  Desulfitobacterium hafniense DCB-2  Bacteria  hitchhiker  0.000000000000188753  n/a   
 
 
-
 
NC_012034  Athe_1456  two component transcriptional regulator, winged helix family  45.05 
 
 
223 aa  206  3e-52  Anaerocellum thermophilum DSM 6725  Bacteria  decreased coverage  0.000183373  n/a   
 
 
-
 
NC_011899  Hore_13280  two component transcriptional regulator, winged helix family  45.95 
 
 
227 aa  206  3e-52  Halothermothrix orenii H 168  Bacteria  hitchhiker  0.0000000536961  n/a   
 
 
-
 
NC_009972  Haur_4663  two component transcriptional regulator  42.04 
 
 
232 aa  205  5e-52  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  n/a   
 
 
-
 
NC_009767  Rcas_0997  two component transcriptional regulator  43.5 
 
 
230 aa  205  5e-52  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.679101  normal 
 
 
-
 
NC_009012  Cthe_1847  two component transcriptional regulator  44.1 
 
 
234 aa  205  5e-52  Clostridium thermocellum ATCC 27405  Bacteria  hitchhiker  0.00000121968  n/a   
 
 
-
 
NC_008699  Noca_3782  response regulator receiver  42.73 
 
 
297 aa  205  6e-52  Nocardioides sp. JS614  Bacteria  normal  n/a   
 
 
-
 
NC_008607  Ppro_3691  two component transcriptional regulator  43.75 
 
 
230 aa  204  7e-52  Pelobacter propionicus DSM 2379  Bacteria  normal  n/a   
 
 
-
 
NC_011831  Cagg_2709  two component transcriptional regulator, winged helix family  46.32 
 
 
236 aa  204  9e-52  Chloroflexus aggregans DSM 9485  Bacteria  decreased coverage  0.0011921  normal 
 
 
-
 
NC_009767  Rcas_0353  two component transcriptional regulator  42.22 
 
 
230 aa  203  2e-51  Roseiflexus castenholzii DSM 13941  Bacteria  normal  normal  0.683455 
 
 
-
 
NC_013947  Snas_0721  two component transcriptional regulator, winged helix family  44.39 
 
 
233 aa  203  2e-51  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  0.811558  normal 
 
 
-
 
NC_010001  Cphy_2121  two component transcriptional regulator  43.56 
 
 
231 aa  202  4e-51  Clostridium phytofermentans ISDg  Bacteria  normal  n/a   
 
 
-
 
NC_014210  Ndas_4670  two component transcriptional regulator, winged helix family  40.89 
 
 
234 aa  201  6e-51  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  normal 
 
 
-
 
NC_009972  Haur_2358  two component transcriptional regulator  43.56 
 
 
231 aa  201  6e-51  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  0.0136772  n/a   
 
 
-
 
NC_010424  Daud_1897  two component transcriptional regulator  44.39 
 
 
227 aa  201  7e-51  Candidatus Desulforudis audaxviator MP104C  Bacteria  normal  0.151466  n/a   
 
 
-
 
NC_009767  Rcas_2782  two component transcriptional regulator  41.96 
 
 
231 aa  200  9.999999999999999e-51  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.92379  normal 
 
 
-
 
NC_013385  Adeg_1028  two component transcriptional regulator, winged helix family  45.02 
 
 
237 aa  200  9.999999999999999e-51  Ammonifex degensii KC4  Bacteria  normal  n/a   
 
 
-
 
NC_014158  Tpau_0093  two component transcriptional regulator, winged helix family  40.87 
 
 
232 aa  201  9.999999999999999e-51  Tsukamurella paurometabola DSM 20162  Bacteria  normal  n/a   
 
 
-
 
NC_013171  Apre_1215  two component transcriptional regulator, winged helix family  43.23 
 
 
237 aa  199  1.9999999999999998e-50  Anaerococcus prevotii DSM 20548  Bacteria  normal  n/a   
 
 
-
 
NC_013552  DhcVS_926  two-component system, OmpR family, response regulator  44.59 
 
 
227 aa  200  1.9999999999999998e-50  Dehalococcoides sp. VS  Bacteria  hitchhiker  0.00200634  n/a   
 
 
-
 
NC_009455  DehaBAV1_0937  two component transcriptional regulator  45.5 
 
 
227 aa  200  1.9999999999999998e-50  Dehalococcoides sp. BAV1  Bacteria  normal  0.834094  n/a   
 
 
-
 
NC_009523  RoseRS_3818  two component transcriptional regulator  43.5 
 
 
230 aa  199  3.9999999999999996e-50  Roseiflexus sp. RS-1  Bacteria  normal  0.386967  normal  0.165932 
 
 
-
 
NC_011831  Cagg_3302  two component transcriptional regulator, winged helix family  41.33 
 
 
231 aa  199  3.9999999999999996e-50  Chloroflexus aggregans DSM 9485  Bacteria  normal  hitchhiker  0.000343135 
 
 
-
 
NC_013169  Ksed_03700  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  43.24 
 
 
226 aa  198  5e-50  Kytococcus sedentarius DSM 20547  Bacteria  normal  normal  0.132847 
 
 
-
 
NC_008148  Rxyl_2983  two component transcriptional regulator  45.05 
 
 
228 aa  198  6e-50  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  n/a   
 
 
-
 
NC_010001  Cphy_1954  two component transcriptional regulator  42.15 
 
 
229 aa  197  7.999999999999999e-50  Clostridium phytofermentans ISDg  Bacteria  decreased coverage  0.000155813  n/a   
 
 
-
 
NC_011831  Cagg_0393  two component transcriptional regulator, winged helix family  43.17 
 
 
227 aa  197  2.0000000000000003e-49  Chloroflexus aggregans DSM 9485  Bacteria  normal  normal  0.202895 
 
 
-
 
NC_012793  GWCH70_2675  two component transcriptional regulator, winged helix family  42.48 
 
 
234 aa  196  3e-49  Geobacillus sp. WCH70  Bacteria  normal  0.661044  n/a   
 
 
-
 
NC_014212  Mesil_0142  two component transcriptional regulator, winged helix family  45.74 
 
 
221 aa  196  3e-49  Meiothermus silvanus DSM 9946  Bacteria  normal  normal  0.709604 
 
 
-
 
NC_013530  Xcel_2485  two component transcriptional regulator, winged helix family  41.18 
 
 
243 aa  195  4.0000000000000005e-49  Xylanimonas cellulosilytica DSM 15894  Bacteria  normal  n/a   
 
 
-
 
NC_014151  Cfla_3537  two component transcriptional regulator, winged helix family  37.55 
 
 
237 aa  195  5.000000000000001e-49  Cellulomonas flavigena DSM 20109  Bacteria  normal  normal  0.555413 
 
 
-
 
NC_008578  Acel_0088  two component transcriptional regulator  41.44 
 
 
228 aa  195  5.000000000000001e-49  Acidothermus cellulolyticus 11B  Bacteria  normal  normal 
 
 
-
 
NC_012803  Mlut_18360  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  40.61 
 
 
239 aa  194  9e-49  Micrococcus luteus NCTC 2665  Bacteria  normal  n/a   
 
 
-
 
NC_012803  Mlut_03750  PhoP-like protein  42.41 
 
 
226 aa  194  1e-48  Micrococcus luteus NCTC 2665  Bacteria  normal  0.181369  n/a   
 
 
-
 
NC_009953  Sare_3070  two component transcriptional regulator  43.5 
 
 
230 aa  194  1e-48  Salinispora arenicola CNS-205  Bacteria  normal  hitchhiker  0.00000463151 
 
 
-
 
NC_009380  Strop_0624  two component transcriptional regulator  42.79 
 
 
240 aa  193  2e-48  Salinispora tropica CNB-440  Bacteria  normal  normal 
 
 
-
 
NC_013159  Svir_02690  response regulator with CheY-like receiver domain protein and winged-helix DNA-binding domain protein  43.3 
 
 
229 aa  193  2e-48  Saccharomonospora viridis DSM 43017  Bacteria  normal  normal 
 
 
-
 
NC_014165  Tbis_0499  winged helix family two component transcriptional regulator  42.86 
 
 
229 aa  193  2e-48  Thermobispora bispora DSM 43833  Bacteria  normal  normal 
 
 
-
 
NC_011898  Ccel_1658  two component transcriptional regulator, winged helix family  42.34 
 
 
230 aa  192  3e-48  Clostridium cellulolyticum H10  Bacteria  normal  0.515101  n/a   
 
 
-
 
NC_013216  Dtox_1077  two component transcriptional regulator, winged helix family  43.23 
 
 
235 aa  192  3e-48  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  normal 
 
 
-
 
NC_010814  Glov_2933  two component transcriptional regulator, winged helix family  42.79 
 
 
233 aa  192  4e-48  Geobacter lovleyi SZ  Bacteria  normal  0.0164541  n/a   
 
 
-
 
NC_010001  Cphy_3429  two component transcriptional regulator  41.7 
 
 
233 aa  192  4e-48  Clostridium phytofermentans ISDg  Bacteria  normal  0.0608192  n/a   
 
 
-
 
NC_007413  Ava_1944  two component transcriptional regulator  42.11 
 
 
238 aa  192  4e-48  Anabaena variabilis ATCC 29413  Bacteria  normal  normal 
 
 
-
 
NC_009253  Dred_1903  two component transcriptional regulator  45.33 
 
 
230 aa  192  4e-48  Desulfotomaculum reducens MI-1  Bacteria  normal  n/a   
 
 
-
 
NC_013172  Bfae_09290  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  42.15 
 
 
229 aa  191  6e-48  Brachybacterium faecium DSM 4810  Bacteria  normal  n/a   
 
 
-
 
NC_011898  Ccel_1892  two component transcriptional regulator, winged helix family  43.24 
 
 
228 aa  191  9e-48  Clostridium cellulolyticum H10  Bacteria  hitchhiker  0.0000392  n/a   
 
 
-
 
NC_013169  Ksed_04920  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  40.17 
 
 
222 aa  191  9e-48  Kytococcus sedentarius DSM 20547  Bacteria  normal  normal 
 
 
-
 
NC_010718  Nther_1220  two component transcriptional regulator, winged helix family  40.89 
 
 
233 aa  191  1e-47  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  hitchhiker  0.00991602 
 
 
-
 
NC_007644  Moth_0070  two component transcriptional regulator  42.22 
 
 
229 aa  190  1e-47  Moorella thermoacetica ATCC 39073  Bacteria  normal  normal  0.834843 
 
 
-
 
NC_009253  Dred_0707  two component transcriptional regulator  43.72 
 
 
232 aa  191  1e-47  Desulfotomaculum reducens MI-1  Bacteria  normal  n/a   
 
 
-
 
NC_009513  Lreu_0019  two component transcriptional regulator  42.73 
 
 
235 aa  189  2e-47  Lactobacillus reuteri DSM 20016  Bacteria  normal  n/a   
 
 
-
 
NC_013595  Sros_1549  response regulator receiver protein  40.36 
 
 
241 aa  190  2e-47  Streptosporangium roseum DSM 43021  Bacteria  normal  0.0273908  normal 
 
 
-
 
NC_011830  Dhaf_1673  two component transcriptional regulator, winged helix family  42.48 
 
 
233 aa  190  2e-47  Desulfitobacterium hafniense DCB-2  Bacteria  normal  n/a   
 
 
-
 
NC_011772  BCG9842_B0458  DNA-binding response regulator  40 
 
 
229 aa  189  2e-47  Bacillus cereus G9842  Bacteria  normal  hitchhiker  0.00396749 
 
 
-
 
NC_009565  TBFG_10499  two component system sensor transduction protein regX3  40.81 
 
 
227 aa  189  2e-47  Mycobacterium tuberculosis F11  Bacteria  decreased coverage  2.46064e-66  normal 
 
 
-
 
NC_009972  Haur_3061  two component transcriptional regulator  43.81 
 
 
227 aa  189  2.9999999999999997e-47  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  0.799336  n/a   
 
 
-
 
NC_013385  Adeg_0644  two component transcriptional regulator, winged helix family  40.95 
 
 
236 aa  189  2.9999999999999997e-47  Ammonifex degensii KC4  Bacteria  normal  n/a   
 
 
-
 
NC_011773  BCAH820_4786  DNA-binding response regulator  40.44 
 
 
229 aa  189  2.9999999999999997e-47  Bacillus cereus AH820  Bacteria  n/a    normal 
 
 
-
 
NC_014151  Cfla_3676  two component transcriptional regulator, winged helix family  39.21 
 
 
243 aa  189  2.9999999999999997e-47  Cellulomonas flavigena DSM 20109  Bacteria  normal  normal 
 
 
-
 
NC_011729  PCC7424_2845  two component transcriptional regulator, winged helix family  41.81 
 
 
234 aa  189  4e-47  Cyanothece sp. PCC 7424  Bacteria  n/a    normal 
 
 
-
 
NC_007333  Tfu_2910  response regulator receiver  41.89 
 
 
230 aa  189  4e-47  Thermobifida fusca YX  Bacteria  normal  n/a   
 
 
-
 
NC_011830  Dhaf_0940  two component transcriptional regulator, winged helix family  42.6 
 
 
237 aa  189  4e-47  Desulfitobacterium hafniense DCB-2  Bacteria  normal  0.324642  n/a   
 
 
-
 
NC_008346  Swol_1681  response regulator receiver protein  43.3 
 
 
227 aa  189  4e-47  Syntrophomonas wolfei subsp. wolfei str. Goettingen  Bacteria  normal  0.0956507  n/a   
 
 
-
 
NC_008010  Dgeo_2564  two component transcriptional regulator  42.86 
 
 
244 aa  188  5e-47  Deinococcus geothermalis DSM 11300  Bacteria  normal  n/a   
 
 
-
 
NC_010320  Teth514_0439  two component transcriptional regulator  44.09 
 
 
225 aa  188  5e-47  Thermoanaerobacter sp. X514  Bacteria  unclonable  0.000000000223011  n/a   
 
 
-
 
NC_008532  STER_1116  DNA-binding response regulator  43.29 
 
 
235 aa  188  5.999999999999999e-47  Streptococcus thermophilus LMD-9  Bacteria  normal  0.310768  n/a   
 
 
-
 
NC_013235  Namu_2566  two component transcriptional regulator, winged helix family  39.01 
 
 
229 aa  188  7e-47  Nakamurella multipartita DSM 44233  Bacteria  hitchhiker  0.000356007  hitchhiker  0.00345607 
 
 
-
 
NC_010814  Glov_0588  two component transcriptional regulator, winged helix family  43.56 
 
 
226 aa  188  7e-47  Geobacter lovleyi SZ  Bacteria  normal  0.944339  n/a   
 
 
-
 
NC_005945  BAS4565  DNA-binding response regulator  40.44 
 
 
233 aa  187  8e-47  Bacillus anthracis str. Sterne  Bacteria  normal  n/a   
 
 
-
 
NC_009487  SaurJH9_0018  two component transcriptional regulator  44.64 
 
 
233 aa  188  8e-47  Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  0.70243  n/a   
 
 
-
 
NC_013510  Tcur_1461  two component transcriptional regulator, winged helix family  38.43 
 
 
225 aa  187  8e-47  Thermomonospora curvata DSM 43183  Bacteria  normal  0.616357  n/a   
 
 
-
 
NC_009632  SaurJH1_0018  response regulator receiver  44.64 
 
 
233 aa  188  8e-47  Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  n/a   
 
 
-
 
NC_009674  Bcer98_2250  two component transcriptional regulator  41.26 
 
 
225 aa  188  8e-47  Bacillus cytotoxicus NVH 391-98  Bacteria  decreased coverage  0.00000295266  n/a   
 
 
-
 
NC_007530  GBAA_4920  DNA-binding response regulator  40.44 
 
 
229 aa  187  9e-47  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  n/a   
 
 
-
 
NC_009012  Cthe_2333  two component transcriptional regulator  40.53 
 
 
232 aa  187  9e-47  Clostridium thermocellum ATCC 27405  Bacteria  normal  n/a   
 
 
-
 
NC_002939  GSU1102  DNA-binding response regulator  44.25 
 
 
225 aa  187  1e-46  Geobacter sulfurreducens PCA  Bacteria  normal  n/a   
 
 
-
 
NC_013947  Snas_5345  two component transcriptional regulator, winged helix family  39.01 
 
 
230 aa  187  1e-46  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  normal  0.264155 
 
 
-
 
NC_011658  BCAH187_A4803  DNA-binding response regulator  40 
 
 
229 aa  187  1e-46  Bacillus cereus AH187  Bacteria  normal  n/a   
 
 
-
 
NC_005957  BT9727_4400  DNA-binding response regulator  40 
 
 
233 aa  187  1e-46  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  n/a   
 
 
-
 
NC_011725  BCB4264_A4781  DNA-binding response regulator  40 
 
 
229 aa  187  1e-46  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_014210  Ndas_4322  two component transcriptional regulator, winged helix family  41.89 
 
 
231 aa  187  1e-46  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  normal 
 
 
-
 
NC_011831  Cagg_0243  two component transcriptional regulator, winged helix family  40.53 
 
 
235 aa  187  1e-46  Chloroflexus aggregans DSM 9485  Bacteria  normal  0.0646165  normal 
 
 
-
 
NC_008527  LACR_0444  DNA-binding response regulator  41.07 
 
 
233 aa  187  1e-46  Lactococcus lactis subsp. cremoris SK11  Bacteria  normal  n/a   
 
 
-
 
NC_008541  Arth_1441  two component transcriptional regulator  39.46 
 
 
247 aa  187  1e-46  Arthrobacter sp. FB24  Bacteria  normal  0.167327  n/a   
 
 
-
 
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