More than 300 homologs were found in PanDaTox collection
for query gene Mpal_2460 on replicon NC_011832
Organism: Methanosphaerula palustris E1-9c



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_011832  Mpal_2460  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  100 
 
 
971 aa  1965    Methanosphaerula palustris E1-9c  Archaea  normal  normal 
 
 
-
 
NC_007298  Daro_2045  CheB methylesterase:MCP methyltransferase, CheR-type  59.01 
 
 
868 aa  973    Dechloromonas aromatica RCB  Bacteria  normal  normal 
 
 
-
 
NC_014248  Aazo_2376  signal transduction histidine kinase with CheB and CheR activity  39.47 
 
 
1407 aa  716    'Nostoc azollae' 0708  Bacteria  normal  n/a   
 
 
-
 
NC_007355  Mbar_A2183  hypothetical protein  44.36 
 
 
980 aa  754    Methanosarcina barkeri str. Fusaro  Archaea  normal  normal  0.850093 
 
 
-
 
NC_007413  Ava_0314  Signal transduction histidine kinase (STHK) with CheB and CheR activity  41.08 
 
 
1399 aa  735    Anabaena variabilis ATCC 29413  Bacteria  normal  normal 
 
 
-
 
NC_009712  Mboo_0327  putative PAS/PAC sensor protein  47.09 
 
 
1008 aa  887    Candidatus Methanoregula boonei 6A8  Archaea  normal  normal 
 
 
-
 
NC_007514  Cag_0563  putative PAS/PAC sensor protein  55.21 
 
 
1035 aa  963    Chlorobium chlorochromatii CaD3  Bacteria  normal  n/a   
 
 
-
 
NC_007517  Gmet_0780  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  58.08 
 
 
887 aa  999    Geobacter metallireducens GS-15  Bacteria  normal  normal 
 
 
-
 
NC_011060  Ppha_1653  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  54.71 
 
 
993 aa  1003    Pelodictyon phaeoclathratiforme BU-1  Bacteria  normal  n/a   
 
 
-
 
NC_010625  Bphy_6399  signal transduction histidine kinase with CheB and CheR activity  39.76 
 
 
1361 aa  638    Burkholderia phymatum STM815  Bacteria  normal  0.191888  normal 
 
 
-
 
NC_013173  Dbac_2162  MCP methyltransferase/methylesterase, CheR/CheB  59.81 
 
 
879 aa  1019    Desulfomicrobium baculatum DSM 4028  Bacteria  normal  n/a   
 
 
-
 
NC_007908  Rfer_2355  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  48.19 
 
 
1008 aa  775    Rhodoferax ferrireducens T118  Bacteria  normal  0.71741  n/a   
 
 
-
 
NC_007908  Rfer_3013  MCP methyltransferase, CheR-type  54.69 
 
 
877 aa  912    Rhodoferax ferrireducens T118  Bacteria  normal  0.404945  n/a   
 
 
-
 
NC_011060  Ppha_0229  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  59.4 
 
 
1138 aa  1004    Pelodictyon phaeoclathratiforme BU-1  Bacteria  normal  n/a   
 
 
-
 
NC_008340  Mlg_1118  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  48.99 
 
 
852 aa  776    Alkalilimnicola ehrlichii MLHE-1  Bacteria  normal  normal  0.742809 
 
 
-
 
NC_008639  Cpha266_1788  putative PAS/PAC sensor protein  57.58 
 
 
998 aa  1009    Chlorobium phaeobacteroides DSM 266  Bacteria  normal  n/a   
 
 
-
 
NC_008709  Ping_1840  MCP methyltransferase, CheR-type  54.52 
 
 
840 aa  927    Psychromonas ingrahamii 37  Bacteria  normal  0.59391  normal  0.603716 
 
 
-
 
NC_008709  Ping_2549  fused CheR-type MCP methyltransferase and PAS sensor protein  41.91 
 
 
1006 aa  707    Psychromonas ingrahamii 37  Bacteria  normal  normal 
 
 
-
 
NC_008709  Ping_3128  MCP methyltransferase, CheR-type  55.38 
 
 
840 aa  931    Psychromonas ingrahamii 37  Bacteria  normal  normal 
 
 
-
 
NC_010803  Clim_1600  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  55.74 
 
 
1000 aa  998    Chlorobium limicola DSM 245  Bacteria  normal  n/a   
 
 
-
 
NC_007348  Reut_B4915  PAS  39.34 
 
 
1384 aa  623  1e-177  Ralstonia eutropha JMP134  Bacteria  normal  n/a   
 
 
-
 
NC_007643  Rru_A1500  Signal transduction histidine kinase (STHK) with CheB and CheR activity  40.94 
 
 
1483 aa  617  1e-175  Rhodospirillum rubrum ATCC 11170  Bacteria  normal  n/a   
 
 
-
 
NC_008781  Pnap_1703  signal transduction histidine kinase with CheB and CheR activity  38.15 
 
 
1408 aa  611  1e-173  Polaromonas naphthalenivorans CJ2  Bacteria  normal  0.433463  normal 
 
 
-
 
NC_010581  Bind_0707  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  40.56 
 
 
1190 aa  603  1.0000000000000001e-171  Beijerinckia indica subsp. indica ATCC 9039  Bacteria  normal  normal 
 
 
-
 
NC_009620  Smed_4278  putative PAS/PAC sensor protein  38.43 
 
 
1027 aa  599  1e-170  Sinorhizobium medicae WSM419  Bacteria  normal  normal 
 
 
-
 
NC_009467  Acry_3169  signal transduction histidine kinase with CheB and CheR activity  40.31 
 
 
1445 aa  600  1e-170  Acidiphilium cryptum JF-5  Bacteria  normal  n/a   
 
 
-
 
NC_013173  Dbac_1410  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  37.36 
 
 
1120 aa  602  1e-170  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  0.132886  n/a   
 
 
-
 
NC_010580  Bind_3835  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  38.76 
 
 
1167 aa  598  1e-169  Beijerinckia indica subsp. indica ATCC 9039  Bacteria  normal  normal 
 
 
-
 
NC_009621  Smed_5776  putative PAS/PAC sensor protein  37.08 
 
 
1160 aa  593  1e-168  Sinorhizobium medicae WSM419  Bacteria  normal  0.491611  normal  0.0137055 
 
 
-
 
NC_013132  Cpin_4422  signal transduction histidine kinase with CheB and CheR activity  39.32 
 
 
1274 aa  590  1e-167  Chitinophaga pinensis DSM 2588  Bacteria  normal  0.381764  normal 
 
 
-
 
NC_008752  Aave_2417  signal transduction histidine kinase with CheB and CheR activity  38.91 
 
 
1535 aa  591  1e-167  Acidovorax citrulli AAC00-1  Bacteria  normal  0.117494  normal 
 
 
-
 
NC_008789  Hhal_1716  MCP methyltransferase, CheR-type  40.02 
 
 
856 aa  586  1e-166  Halorhodospira halophila SL1  Bacteria  normal  0.92135  n/a   
 
 
-
 
NC_013037  Dfer_5571  signal transduction histidine kinase with CheB and CheR activity  38.66 
 
 
1218 aa  583  1.0000000000000001e-165  Dyadobacter fermentans DSM 18053  Bacteria  normal  0.273526  normal 
 
 
-
 
NC_007961  Nham_4605  MCP methyltransferase, CheR-type  38.97 
 
 
1092 aa  585  1.0000000000000001e-165  Nitrobacter hamburgensis X14  Bacteria  normal  0.315944  n/a   
 
 
-
 
NC_010322  PputGB1_3018  signal transduction histidine kinase with CheB and CheR activity  39.05 
 
 
1371 aa  582  1.0000000000000001e-165  Pseudomonas putida GB-1  Bacteria  normal  normal  0.980757 
 
 
-
 
NC_008609  Ppro_3165  signal transduction histidine kinase with CheB and CheR activity  39.36 
 
 
1306 aa  576  1.0000000000000001e-163  Pelobacter propionicus DSM 2379  Bacteria  normal  n/a   
 
 
-
 
NC_007484  Noc_1601  CheB methylesterase, CheR methyltransferase, hybrid histidine kinase  39.26 
 
 
1222 aa  573  1.0000000000000001e-162  Nitrosococcus oceani ATCC 19707  Bacteria  normal  0.472526  n/a   
 
 
-
 
NC_013440  Hoch_3250  signal transduction histidine kinase with CheB and CheR activity  36.98 
 
 
1348 aa  575  1.0000000000000001e-162  Haliangium ochraceum DSM 14365  Bacteria  normal  0.534329  normal  0.0270765 
 
 
-
 
NC_007955  Mbur_0399  MCP methyltransferase, CheR-type  36.17 
 
 
820 aa  570  1e-161  Methanococcoides burtonii DSM 6242  Archaea  normal  n/a   
 
 
-
 
NC_013037  Dfer_5176  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  38.04 
 
 
1404 aa  566  1e-160  Dyadobacter fermentans DSM 18053  Bacteria  normal  normal  0.190634 
 
 
-
 
NC_007760  Adeh_3183  signal transduction histidine kinase  39.16 
 
 
1279 aa  564  1.0000000000000001e-159  Anaeromyxobacter dehalogenans 2CP-C  Bacteria  normal  n/a   
 
 
-
 
NC_011004  Rpal_3739  MCP methyltransferase, CheR-type  40.43 
 
 
1045 aa  565  1.0000000000000001e-159  Rhodopseudomonas palustris TIE-1  Bacteria  normal  n/a   
 
 
-
 
NC_008789  Hhal_0370  protein-glutamate O-methyltransferase  48.57 
 
 
639 aa  565  1.0000000000000001e-159  Halorhodospira halophila SL1  Bacteria  normal  0.181962  n/a   
 
 
-
 
NC_011145  AnaeK_0372  signal transduction histidine kinase with CheB and CheR activity  40.09 
 
 
1233 aa  560  1e-158  Anaeromyxobacter sp. K  Bacteria  normal  n/a   
 
 
-
 
NC_011891  A2cp1_3377  signal transduction histidine kinase with CheB and CheR activity  39.04 
 
 
1242 aa  560  1e-158  Anaeromyxobacter dehalogenans 2CP-1  Bacteria  normal  n/a   
 
 
-
 
NC_007912  Sde_3046  hypothetical protein  36.75 
 
 
1010 aa  548  1e-154  Saccharophagus degradans 2-40  Bacteria  normal  hitchhiker  0.00164382 
 
 
-
 
NC_010086  Bmul_3193  signal transduction histidine kinase with CheB and CheR activity  37.32 
 
 
1380 aa  545  1e-153  Burkholderia multivorans ATCC 17616  Bacteria  normal  normal  0.112764 
 
 
-
 
NC_013132  Cpin_7206  signal transduction histidine kinase with CheB and CheR activity  36.24 
 
 
1499 aa  540  9.999999999999999e-153  Chitinophaga pinensis DSM 2588  Bacteria  normal  normal 
 
 
-
 
NC_013205  Aaci_0673  signal transduction histidine kinase with CheB and CheR activity  34.98 
 
 
1215 aa  538  1e-151  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  n/a   
 
 
-
 
NC_010725  Mpop_1297  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  38.17 
 
 
1168 aa  535  1e-150  Methylobacterium populi BJ001  Bacteria  normal  normal 
 
 
-
 
NC_010511  M446_6211  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  38.42 
 
 
1061 aa  528  1e-148  Methylobacterium sp. 4-46  Bacteria  normal  0.820077  normal  0.703655 
 
 
-
 
NC_010725  Mpop_0310  MCP methyltransferase, CheR-type  38.24 
 
 
1149 aa  522  1e-146  Methylobacterium populi BJ001  Bacteria  normal  0.512157  normal 
 
 
-
 
NC_011368  Rleg2_5237  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  37.39 
 
 
1324 aa  521  1e-146  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  normal  0.395635 
 
 
-
 
NC_013061  Phep_3913  PAS sensor protein  34.59 
 
 
1337 aa  518  1.0000000000000001e-145  Pedobacter heparinus DSM 2366  Bacteria  normal  0.290527  normal  0.28306 
 
 
-
 
NC_010510  Mrad2831_6264  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  39.81 
 
 
1163 aa  519  1.0000000000000001e-145  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  normal 
 
 
-
 
NC_013440  Hoch_1404  signal transduction histidine kinase with CheB and CheR activity  38.53 
 
 
1759 aa  513  1e-144  Haliangium ochraceum DSM 14365  Bacteria  normal  normal 
 
 
-
 
NC_011894  Mnod_3755  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  38.66 
 
 
1063 aa  512  1e-143  Methylobacterium nodulans ORS 2060  Bacteria  normal  n/a   
 
 
-
 
NC_010505  Mrad2831_4430  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  37.85 
 
 
1158 aa  508  9.999999999999999e-143  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  normal 
 
 
-
 
NC_013440  Hoch_5252  signal transduction histidine kinase with CheB and CheR activity  36.49 
 
 
1698 aa  500  1e-140  Haliangium ochraceum DSM 14365  Bacteria  normal  normal 
 
 
-
 
NC_007953  Bxe_C0521  multi sensor hybrid histidine kinase  35.13 
 
 
1344 aa  500  1e-140  Burkholderia xenovorans LB400  Bacteria  normal  normal 
 
 
-
 
NC_007493  RSP_2229  methylesterase CheB/methylase CheR  36.61 
 
 
1170 aa  495  9.999999999999999e-139  Rhodobacter sphaeroides 2.4.1  Bacteria  normal  0.840236  n/a   
 
 
-
 
NC_013440  Hoch_3278  signal transduction histidine kinase with CheB and CheR activity  35.33 
 
 
2468 aa  494  9.999999999999999e-139  Haliangium ochraceum DSM 14365  Bacteria  normal  normal  0.0267066 
 
 
-
 
NC_009049  Rsph17029_0905  putative PAS/PAC sensor protein  36.61 
 
 
1170 aa  495  9.999999999999999e-139  Rhodobacter sphaeroides ATCC 17029  Bacteria  normal  normal  0.968727 
 
 
-
 
NC_010505  Mrad2831_5709  MCP methyltransferase, CheR-type  36.78 
 
 
853 aa  489  1e-136  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  normal  0.729466 
 
 
-
 
NC_013730  Slin_3102  signal transduction histidine kinase with CheB and CheR activity  38.59 
 
 
1418 aa  488  1e-136  Spirosoma linguale DSM 74  Bacteria  normal  normal 
 
 
-
 
NC_013440  Hoch_4639  signal transduction histidine kinase with CheB and CheR activity  34.91 
 
 
1453 aa  484  1e-135  Haliangium ochraceum DSM 14365  Bacteria  normal  0.432269  normal 
 
 
-
 
NC_008255  CHU_1237  chemotaxis response regulator (methyltransferase)  35.11 
 
 
1618 aa  482  1e-134  Cytophaga hutchinsonii ATCC 33406  Bacteria  normal  normal 
 
 
-
 
NC_009428  Rsph17025_2264  putative PAS/PAC sensor protein  36.42 
 
 
1165 aa  479  1e-133  Rhodobacter sphaeroides ATCC 17025  Bacteria  normal  0.620072  normal  0.0600346 
 
 
-
 
NC_007952  Bxe_B1520  signal transduction histidine kinase (STHK) with CheB and CheR activity  35.31 
 
 
1303 aa  476  1e-133  Burkholderia xenovorans LB400  Bacteria  normal  0.124967  normal 
 
 
-
 
NC_014230  CA2559_12648  Signal Transduction Histidine Kinase (STHK) with CheB and CheRactivity  31.29 
 
 
1200 aa  471  1.0000000000000001e-131  Croceibacter atlanticus HTCC2559  Bacteria  normal  n/a   
 
 
-
 
NC_008751  Dvul_2487  signal transduction histidine kinase with CheB and CheR activity  37.11 
 
 
1535 aa  471  1.0000000000000001e-131  Desulfovibrio vulgaris DP4  Bacteria  normal  0.162467  normal  0.455724 
 
 
-
 
NC_008044  TM1040_1028  signal transduction histidine kinase with CheB and CheR activity  35.27 
 
 
1248 aa  465  1e-129  Ruegeria sp. TM1040  Bacteria  normal  normal  0.507304 
 
 
-
 
NC_008576  Mmc1_3390  MCP methyltransferase, CheR-type  41.03 
 
 
617 aa  438  1e-121  Magnetococcus sp. MC-1  Bacteria  normal  normal 
 
 
-
 
NC_008044  TM1040_0460  MCP methyltransferase, CheR-type  34.15 
 
 
837 aa  417  9.999999999999999e-116  Ruegeria sp. TM1040  Bacteria  normal  0.604812  normal 
 
 
-
 
NC_010508  Bcenmc03_1302  signal transduction histidine kinase with CheB and CheR activity  34.14 
 
 
1220 aa  408  1.0000000000000001e-112  Burkholderia cenocepacia MC0-3  Bacteria  normal  normal  0.772751 
 
 
-
 
NC_002977  MCA1246  methyltransferase CheR, putative  33.41 
 
 
1378 aa  402  9.999999999999999e-111  Methylococcus capsulatus str. Bath  Bacteria  normal  0.271052  n/a   
 
 
-
 
NC_010086  Bmul_4696  signal transduction histidine kinase with CheB and CheR activity  32.93 
 
 
1214 aa  402  9.999999999999999e-111  Burkholderia multivorans ATCC 17616  Bacteria  normal  normal 
 
 
-
 
NC_008044  TM1040_2227  MCP methyltransferase, CheR-type  34.62 
 
 
824 aa  398  1e-109  Ruegeria sp. TM1040  Bacteria  normal  normal 
 
 
-
 
NC_007802  Jann_2564  MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor  32.56 
 
 
1089 aa  395  1e-108  Jannaschia sp. CCS1  Bacteria  normal  normal 
 
 
-
 
NC_010623  Bphy_5175  MCP methyltransferase, CheR-type  32.52 
 
 
823 aa  389  1e-106  Burkholderia phymatum STM815  Bacteria  normal  normal  0.367936 
 
 
-
 
NC_009622  Smed_6341  putative PAS/PAC sensor protein  41.2 
 
 
629 aa  375  1e-102  Sinorhizobium medicae WSM419  Bacteria  normal  0.433344  normal  0.230755 
 
 
-
 
NC_007348  Reut_B5191  CheB methylesterase:MCP methyltransferase, CheR-type  31.72 
 
 
813 aa  370  1e-101  Ralstonia eutropha JMP134  Bacteria  normal  n/a   
 
 
-
 
NC_010814  Glov_0566  MCP methyltransferase, CheR-type with PAS/PAC sensor  36.11 
 
 
1193 aa  370  1e-100  Geobacter lovleyi SZ  Bacteria  normal  n/a   
 
 
-
 
NC_010814  Glov_2975  diguanylate cyclase with PAS/PAC sensor  35.78 
 
 
1084 aa  363  6e-99  Geobacter lovleyi SZ  Bacteria  normal  n/a   
 
 
-
 
NC_013730  Slin_1989  MCP methyltransferase, CheR-type with PAS/PAC sensor  36.71 
 
 
1110 aa  356  8.999999999999999e-97  Spirosoma linguale DSM 74  Bacteria  normal  0.175442  normal  0.013335 
 
 
-
 
NC_007964  Nham_3990  MCP methyltransferase, CheR-type  43.81 
 
 
432 aa  340  9e-92  Nitrobacter hamburgensis X14  Bacteria  normal  n/a   
 
 
-
 
NC_010717  PXO_03023  methyltransferase  38.01 
 
 
604 aa  298  3e-79  Xanthomonas oryzae pv. oryzae PXO99A  Bacteria  normal  0.361036  n/a   
 
 
-
 
NC_013132  Cpin_3640  MCP methyltransferase, CheR-type with PAS/PAC sensor  34.49 
 
 
1303 aa  298  4e-79  Chitinophaga pinensis DSM 2588  Bacteria  normal  normal  0.581797 
 
 
-
 
NC_013440  Hoch_3427  MCP methyltransferase, CheR-type with PAS/PAC sensor  29.38 
 
 
2031 aa  292  2e-77  Haliangium ochraceum DSM 14365  Bacteria  normal  normal  0.0889636 
 
 
-
 
NC_014248  Aazo_0227  MCP methyltransferase  30.74 
 
 
631 aa  273  8.000000000000001e-72  'Nostoc azollae' 0708  Bacteria  normal  0.993793  n/a   
 
 
-
 
NC_011729  PCC7424_0433  MCP methyltransferase, CheR-type with PAS/PAC sensor  32.31 
 
 
618 aa  250  9e-65  Cyanothece sp. PCC 7424  Bacteria  n/a    normal 
 
 
-
 
NC_011884  Cyan7425_3121  MCP methyltransferase, CheR-type with PAS/PAC sensor  30.86 
 
 
617 aa  233  1e-59  Cyanothece sp. PCC 7425  Bacteria  normal  0.0152355  normal  0.805919 
 
 
-
 
NC_009622  Smed_6342  CheB methylesterase  41.39 
 
 
336 aa  224  6e-57  Sinorhizobium medicae WSM419  Bacteria  normal  0.582664  normal  0.191496 
 
 
-
 
NC_012918  GM21_1720  MCP methyltransferase, CheR-type  37.65 
 
 
278 aa  166  2.0000000000000002e-39  Geobacter sp. M21  Bacteria  n/a    hitchhiker  0.000122266 
 
 
-
 
NC_008576  Mmc1_2635  CheB methylesterase  38.03 
 
 
262 aa  164  8.000000000000001e-39  Magnetococcus sp. MC-1  Bacteria  normal  0.177706  normal 
 
 
-
 
NC_011146  Gbem_2497  MCP methyltransferase, CheR-type  38.15 
 
 
278 aa  162  4e-38  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_011830  Dhaf_4203  MCP methyltransferase, CheR-type  32.24 
 
 
264 aa  160  1e-37  Desulfitobacterium hafniense DCB-2  Bacteria  normal  0.0106813  n/a   
 
 
-
 
NC_008576  Mmc1_2113  MCP methyltransferase, CheR-type  27.31 
 
 
565 aa  158  4e-37  Magnetococcus sp. MC-1  Bacteria  normal  0.982588  normal 
 
 
-
 
NC_008576  Mmc1_3393  putative PAS/PAC sensor protein  41.84 
 
 
545 aa  157  1e-36  Magnetococcus sp. MC-1  Bacteria  normal  normal 
 
 
-
 
NC_010718  Nther_1604  MCP methyltransferase, CheR-type  35.6 
 
 
260 aa  156  2e-36  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  0.0143514  unclonable  1.76137e-23 
 
 
-
 
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