More than 300 homologs were found in PanDaTox collection
for query gene Mpal_2157 on replicon NC_011832
Organism: Methanosphaerula palustris E1-9c



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_011832  Mpal_2157  response regulator receiver protein  100 
 
 
140 aa  282  1.0000000000000001e-75  Methanosphaerula palustris E1-9c  Archaea  normal  normal 
 
 
-
 
NC_009712  Mboo_1937  response regulator receiver protein  43.48 
 
 
209 aa  140  8e-33  Candidatus Methanoregula boonei 6A8  Archaea  normal  0.224265  normal 
 
 
-
 
NC_009712  Mboo_1936  response regulator receiver protein  49.19 
 
 
221 aa  135  1e-31  Candidatus Methanoregula boonei 6A8  Archaea  normal  0.941096  normal 
 
 
-
 
NC_011832  Mpal_2156  response regulator receiver protein  45.59 
 
 
212 aa  130  5e-30  Methanosphaerula palustris E1-9c  Archaea  normal  normal 
 
 
-
 
NC_009051  Memar_0309  response regulator receiver protein  43.38 
 
 
211 aa  129  1.0000000000000001e-29  Methanoculleus marisnigri JR1  Archaea  normal  n/a   
 
 
-
 
NC_009051  Memar_0295  response regulator receiver protein  43.38 
 
 
211 aa  129  1.0000000000000001e-29  Methanoculleus marisnigri JR1  Archaea  normal  n/a   
 
 
-
 
NC_007796  Mhun_1618  response regulator receiver domain-containing protein  44.12 
 
 
208 aa  128  2.0000000000000002e-29  Methanospirillum hungatei JF-1  Archaea  normal  normal 
 
 
-
 
NC_009712  Mboo_2365  response regulator receiver protein  38.97 
 
 
221 aa  113  7.999999999999999e-25  Candidatus Methanoregula boonei 6A8  Archaea  normal  0.878823  normal 
 
 
-
 
NC_009712  Mboo_0965  response regulator receiver protein  42.15 
 
 
411 aa  101  3e-21  Candidatus Methanoregula boonei 6A8  Archaea  normal  0.656429  normal  0.215977 
 
 
-
 
NC_009712  Mboo_1478  response regulator receiver protein  39.5 
 
 
426 aa  98.2  3e-20  Candidatus Methanoregula boonei 6A8  Archaea  normal  0.274981  normal 
 
 
-
 
NC_007796  Mhun_1472  response regulator receiver domain-containing protein  38.21 
 
 
216 aa  94.7  3e-19  Methanospirillum hungatei JF-1  Archaea  normal  normal 
 
 
-
 
NC_013522  Taci_0090  two component transcriptional regulator, winged helix family  35.16 
 
 
228 aa  81.3  0.000000000000004  Thermanaerovibrio acidaminovorans DSM 6589  Bacteria  normal  n/a   
 
 
-
 
NC_007969  Pcryo_2096  CheA signal transduction histidine kinases  35 
 
 
2301 aa  81.3  0.000000000000004  Psychrobacter cryohalolentis K5  Bacteria  normal  normal 
 
 
-
 
NC_007335  PMN2A_1537  two component LuxR family transcriptional regulator  31.85 
 
 
242 aa  80.1  0.00000000000001  Prochlorococcus marinus str. NATL2A  Bacteria  normal  n/a   
 
 
-
 
NC_008819  NATL1_02441  two-component response regulator  31.85 
 
 
242 aa  79.7  0.00000000000001  Prochlorococcus marinus str. NATL1A  Bacteria  normal  0.72299  normal 
 
 
-
 
NC_007796  Mhun_1613  response regulator receiver domain-containing protein  29.85 
 
 
211 aa  79.7  0.00000000000001  Methanospirillum hungatei JF-1  Archaea  normal  normal 
 
 
-
 
NC_009976  P9211_17451  two-component response regulator  30.43 
 
 
269 aa  79.3  0.00000000000002  Prochlorococcus marinus str. MIT 9211  Bacteria  normal  normal 
 
 
-
 
NC_007204  Psyc_1813  putative hybrid two-component sensor and regulatory protein  32.48 
 
 
2284 aa  78.2  0.00000000000004  Psychrobacter arcticus 273-4  Bacteria  normal  0.409027  normal 
 
 
-
 
NC_013216  Dtox_1955  two component transcriptional regulator, winged helix family  35.54 
 
 
236 aa  77.8  0.00000000000005  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  0.295041  normal 
 
 
-
 
NC_007796  Mhun_2638  response regulator receiver domain-containing protein  32.17 
 
 
220 aa  77  0.00000000000008  Methanospirillum hungatei JF-1  Archaea  normal  normal 
 
 
-
 
NC_011146  Gbem_1865  two component transcriptional regulator, winged helix family  31.88 
 
 
226 aa  75.9  0.0000000000002  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_009523  RoseRS_3737  two component transcriptional regulator  30.3 
 
 
231 aa  75.5  0.0000000000002  Roseiflexus sp. RS-1  Bacteria  normal  hitchhiker  0.00273603 
 
 
-
 
NC_008312  Tery_3999  adenylate/guanylate cyclase  33.06 
 
 
351 aa  75.5  0.0000000000002  Trichodesmium erythraeum IMS101  Bacteria  normal  normal  0.558191 
 
 
-
 
NC_009485  BBta_4316  sensor histidine kinase  30.08 
 
 
1695 aa  75.5  0.0000000000002  Bradyrhizobium sp. BTAi1  Bacteria  normal  normal  0.946527 
 
 
-
 
NC_009524  PsycPRwf_2155  CheA signal transduction histidine kinase  30.58 
 
 
1609 aa  75.5  0.0000000000002  Psychrobacter sp. PRwf-1  Bacteria  normal  normal 
 
 
-
 
NC_012848  Rleg_5109  GAF sensor hybrid histidine kinase  32.79 
 
 
2099 aa  75.1  0.0000000000003  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  normal  0.0669819 
 
 
-
 
NC_007347  Reut_A2619  response regulator receiver:CheW-like protein:ATP-binding region, ATPase-like:Hpt  27.5 
 
 
1956 aa  75.1  0.0000000000003  Ralstonia eutropha JMP134  Bacteria  normal  n/a   
 
 
-
 
NC_013739  Cwoe_5381  two component transcriptional regulator, winged helix family  32.8 
 
 
235 aa  75.1  0.0000000000003  Conexibacter woesei DSM 14684  Bacteria  normal  0.0242785  normal 
 
 
-
 
NC_013037  Dfer_0393  histidine kinase  34.68 
 
 
1200 aa  74.7  0.0000000000004  Dyadobacter fermentans DSM 18053  Bacteria  normal  normal  0.564913 
 
 
-
 
NC_007604  Synpcc7942_1860  two component LuxR family transcriptional regulator  28.57 
 
 
235 aa  74.7  0.0000000000004  Synechococcus elongatus PCC 7942  Bacteria  normal  normal 
 
 
-
 
NC_007760  Adeh_1556  response regulator receiver modulated diguanylate cyclase  36.59 
 
 
300 aa  74.7  0.0000000000004  Anaeromyxobacter dehalogenans 2CP-C  Bacteria  normal  n/a   
 
 
-
 
NC_011729  PCC7424_5208  response regulator receiver protein  29.37 
 
 
184 aa  74.7  0.0000000000004  Cyanothece sp. PCC 7424  Bacteria  n/a    hitchhiker  0.0000000457636 
 
 
-
 
NC_007404  Tbd_0216  two component transcriptional regulator  32 
 
 
230 aa  74.3  0.0000000000005  Thiobacillus denitrificans ATCC 25259  Bacteria  normal  normal  0.305183 
 
 
-
 
NC_008554  Sfum_1934  two component, sigma54 specific, Fis family transcriptional regulator  38.52 
 
 
476 aa  74.3  0.0000000000005  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  0.808753  normal  0.132653 
 
 
-
 
NC_012793  GWCH70_0170  two component transcriptional regulator, winged helix family  29.66 
 
 
232 aa  74.3  0.0000000000005  Geobacillus sp. WCH70  Bacteria  normal  n/a   
 
 
-
 
NC_007413  Ava_2239  adenylate/guanylate cyclase  30.83 
 
 
1156 aa  73.9  0.0000000000006  Anabaena variabilis ATCC 29413  Bacteria  normal  0.159061  normal 
 
 
-
 
NC_008789  Hhal_0365  response regulator receiver modulated diguanylate cyclase  40.91 
 
 
308 aa  73.9  0.0000000000006  Halorhodospira halophila SL1  Bacteria  normal  n/a   
 
 
-
 
NC_011901  Tgr7_2900  putative CheA signal transduction histidine kinase  34.43 
 
 
1974 aa  73.9  0.0000000000006  Thioalkalivibrio sp. HL-EbGR7  Bacteria  normal  n/a   
 
 
-
 
NC_013385  Adeg_0644  two component transcriptional regulator, winged helix family  30.25 
 
 
236 aa  73.9  0.0000000000006  Ammonifex degensii KC4  Bacteria  normal  n/a   
 
 
-
 
NC_013216  Dtox_1077  two component transcriptional regulator, winged helix family  29.85 
 
 
235 aa  73.9  0.0000000000007  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  normal 
 
 
-
 
NC_007912  Sde_2977  response regulator receiver domain-containing protein  35.34 
 
 
303 aa  73.9  0.0000000000007  Saccharophagus degradans 2-40  Bacteria  normal  normal  0.13601 
 
 
-
 
NC_007912  Sde_3629  putative CheA signal transduction histidine kinases  34.17 
 
 
2336 aa  73.9  0.0000000000007  Saccharophagus degradans 2-40  Bacteria  normal  normal 
 
 
-
 
NC_009523  RoseRS_3924  response regulator receiver modulated diguanylate cyclase  27.34 
 
 
443 aa  73.6  0.0000000000008  Roseiflexus sp. RS-1  Bacteria  normal  0.350169  normal 
 
 
-
 
NC_009943  Dole_2739  two component, sigma54 specific, Fis family transcriptional regulator  38.18 
 
 
451 aa  73.6  0.0000000000008  Desulfococcus oleovorans Hxd3  Bacteria  normal  0.693002  n/a   
 
 
-
 
NC_009901  Spea_2969  two component transcriptional regulator  32.82 
 
 
229 aa  73.6  0.0000000000008  Shewanella pealeana ATCC 700345  Bacteria  decreased coverage  0.000000855765  n/a   
 
 
-
 
NC_002947  PP_4959  response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)  32.8 
 
 
708 aa  73.6  0.0000000000009  Pseudomonas putida KT2440  Bacteria  normal  0.714982  normal 
 
 
-
 
NC_008347  Mmar10_1277  response regulator receiver modulated diguanylate cyclase  32.82 
 
 
454 aa  73.6  0.0000000000009  Maricaulis maris MCS10  Bacteria  normal  0.410696  normal  0.0388481 
 
 
-
 
NC_009523  RoseRS_0161  response regulator receiver protein  34.19 
 
 
132 aa  73.6  0.0000000000009  Roseiflexus sp. RS-1  Bacteria  normal  normal 
 
 
-
 
NC_011831  Cagg_0599  response regulator receiver modulated diguanylate cyclase  29.6 
 
 
313 aa  72.8  0.000000000001  Chloroflexus aggregans DSM 9485  Bacteria  normal  0.464892  normal  0.548622 
 
 
-
 
NC_002978  WD0221  response regulator PleD  35.54 
 
 
460 aa  72.8  0.000000000001  Wolbachia endosymbiont of Drosophila melanogaster  Bacteria  normal  n/a   
 
 
-
 
NC_009512  Pput_4832  response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)  30.83 
 
 
708 aa  73.2  0.000000000001  Pseudomonas putida F1  Bacteria  normal  normal 
 
 
-
 
NC_009767  Rcas_1504  two component transcriptional regulator  29.37 
 
 
231 aa  72.8  0.000000000001  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.263867  normal  0.57819 
 
 
-
 
NC_007492  Pfl01_5255  diguanylate cyclase/phosphodiesterase  34.71 
 
 
707 aa  72.8  0.000000000001  Pseudomonas fluorescens Pf0-1  Bacteria  normal  0.864356  normal 
 
 
-
 
NC_007604  Synpcc7942_1110  response regulator receiver domain-containing protein  28.81 
 
 
208 aa  73.2  0.000000000001  Synechococcus elongatus PCC 7942  Bacteria  hitchhiker  0.00277439  normal 
 
 
-
 
NC_011830  Dhaf_1237  two component transcriptional regulator, winged helix family  33.83 
 
 
234 aa  73.6  0.000000000001  Desulfitobacterium hafniense DCB-2  Bacteria  normal  0.178035  n/a   
 
 
-
 
NC_012856  Rpic12D_0564  CheA signal transduction histidine kinase  28.1 
 
 
2012 aa  72.8  0.000000000001  Ralstonia pickettii 12D  Bacteria  normal  0.472069  normal 
 
 
-
 
NC_011368  Rleg2_5393  GAF sensor hybrid histidine kinase  32.56 
 
 
2099 aa  73.2  0.000000000001  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  0.0480029  normal  0.0859175 
 
 
-
 
NC_013173  Dbac_2662  two component transcriptional regulator, winged helix family  31.2 
 
 
231 aa  73.2  0.000000000001  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  n/a   
 
 
-
 
NC_004578  PSPTO_5030  sensor histidine kinase/response regulator  31.25 
 
 
1987 aa  72  0.000000000002  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  n/a   
 
 
-
 
NC_007005  Psyr_0492  response regulator receiver:CheW-like protein:ATP-binding region, ATPase-like:Hpt  31.25 
 
 
1992 aa  72  0.000000000002  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  normal 
 
 
-
 
NC_010682  Rpic_0616  CheA signal transduction histidine kinase  27.27 
 
 
2009 aa  72  0.000000000002  Ralstonia pickettii 12J  Bacteria  normal  normal 
 
 
-
 
NC_009636  Smed_0234  response regulator receiver protein  29.17 
 
 
121 aa  72.4  0.000000000002  Sinorhizobium medicae WSM419  Bacteria  normal  0.695764  normal  0.176079 
 
 
-
 
NC_007516  Syncc9605_2427  two component LuxR family transcriptional regulator  26.67 
 
 
245 aa  72.4  0.000000000002  Synechococcus sp. CC9605  Bacteria  normal  0.27075  normal 
 
 
-
 
NC_009675  Anae109_3956  response regulator receiver protein  33.91 
 
 
128 aa  72.4  0.000000000002  Anaeromyxobacter sp. Fw109-5  Bacteria  normal  normal  0.314568 
 
 
-
 
NC_013172  Bfae_20650  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  32.23 
 
 
231 aa  72  0.000000000002  Brachybacterium faecium DSM 4810  Bacteria  normal  0.0260682  n/a   
 
 
-
 
NC_013161  Cyan8802_3207  response regulator receiver protein  29.77 
 
 
186 aa  72.4  0.000000000002  Cyanothece sp. PCC 8802  Bacteria  normal  normal 
 
 
-
 
NC_013385  Adeg_1011  two component transcriptional regulator, winged helix family  30.58 
 
 
231 aa  72.8  0.000000000002  Ammonifex degensii KC4  Bacteria  normal  n/a   
 
 
-
 
NC_010322  PputGB1_5008  response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)  31.67 
 
 
708 aa  72.4  0.000000000002  Pseudomonas putida GB-1  Bacteria  normal  0.100946  normal 
 
 
-
 
NC_011726  PCC8801_2889  response regulator receiver protein  29.77 
 
 
186 aa  72.4  0.000000000002  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_010581  Bind_3302  two component transcriptional regulator  32.61 
 
 
230 aa  72  0.000000000003  Beijerinckia indica subsp. indica ATCC 9039  Bacteria  normal  0.288231  normal  0.346827 
 
 
-
 
NC_003295  RSc0672  putative composite two component regulatory (sensor histidine kinase and response regulator hybrid) transcription regulator protein  27.27 
 
 
2048 aa  72  0.000000000003  Ralstonia solanacearum GMI1000  Bacteria  normal  0.843202  normal 
 
 
-
 
NC_004578  PSPTO_5014  response regulator/sensory box/GGDEF domain/EAL domain protein  31.4 
 
 
719 aa  71.6  0.000000000003  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  n/a   
 
 
-
 
NC_007348  Reut_B4068  response regulator receiver  33.96 
 
 
377 aa  72  0.000000000003  Ralstonia eutropha JMP134  Bacteria  normal  0.706307  n/a   
 
 
-
 
NC_012918  GM21_0975  response regulator receiver sensor signal transduction histidine kinase  38.18 
 
 
383 aa  71.6  0.000000000003  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_007492  Pfl01_5304  CheA Signal transduction histidine Kinases (STHK)  30 
 
 
1971 aa  71.6  0.000000000003  Pseudomonas fluorescens Pf0-1  Bacteria  normal  normal  0.266028 
 
 
-
 
NC_007498  Pcar_2015  two component hybrid sensor response regulator  30.58 
 
 
391 aa  71.6  0.000000000003  Pelobacter carbinolicus DSM 2380  Bacteria  normal  n/a   
 
 
-
 
NC_009972  Haur_1097  response regulator receiver protein  33.33 
 
 
131 aa  72  0.000000000003  Herpetosiphon aurantiacus ATCC 23779  Bacteria  hitchhiker  0.00801176  n/a   
 
 
-
 
NC_008025  Dgeo_1069  response regulator receiver protein  30.58 
 
 
128 aa  71.6  0.000000000003  Deinococcus geothermalis DSM 11300  Bacteria  normal  0.0511705  normal  0.476202 
 
 
-
 
NC_009976  P9211_01871  two-component response regulator  31.15 
 
 
242 aa  71.6  0.000000000003  Prochlorococcus marinus str. MIT 9211  Bacteria  normal  normal 
 
 
-
 
NC_013216  Dtox_1554  two component transcriptional regulator, winged helix family  34.68 
 
 
229 aa  71.6  0.000000000003  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  hitchhiker  0.00709514 
 
 
-
 
NC_009972  Haur_0605  adenylate/guanylate cyclase  36.29 
 
 
355 aa  71.2  0.000000000004  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  0.657653  n/a   
 
 
-
 
NC_010515  Bcenmc03_5666  two component LuxR family transcriptional regulator  38.71 
 
 
312 aa  71.2  0.000000000004  Burkholderia cenocepacia MC0-3  Bacteria  normal  normal  0.917296 
 
 
-
 
NC_009767  Rcas_3309  response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)  34.15 
 
 
900 aa  71.6  0.000000000004  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.269875  normal  0.342346 
 
 
-
 
NC_007005  Psyr_0509  PAS:GGDEF  31.4 
 
 
719 aa  71.6  0.000000000004  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  normal 
 
 
-
 
NC_009972  Haur_0719  multi-sensor signal transduction histidine kinase  34.19 
 
 
531 aa  71.6  0.000000000004  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  n/a   
 
 
-
 
NC_011146  Gbem_3274  response regulator receiver sensor signal transduction histidine kinase  38.18 
 
 
383 aa  71.2  0.000000000004  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_007604  Synpcc7942_1817  response regulator receiver domain-containing protein  31.36 
 
 
121 aa  71.2  0.000000000004  Synechococcus elongatus PCC 7942  Bacteria  normal  normal  0.202035 
 
 
-
 
NC_007798  NSE_0512  response regulator PleD  35.16 
 
 
456 aa  71.2  0.000000000004  Neorickettsia sennetsu str. Miyayama  Bacteria  normal  n/a   
 
 
-
 
NC_007908  Rfer_2262  response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)  34.29 
 
 
853 aa  71.2  0.000000000004  Rhodoferax ferrireducens T118  Bacteria  normal  n/a   
 
 
-
 
NC_014165  Tbis_0845  response regulator receiver protein  29.06 
 
 
125 aa  71.6  0.000000000004  Thermobispora bispora DSM 43833  Bacteria  normal  0.455865  normal  0.167506 
 
 
-
 
NC_007955  Mbur_2445  response regulator receiver  32.23 
 
 
125 aa  71.2  0.000000000004  Methanococcoides burtonii DSM 6242  Archaea  normal  0.942791  n/a   
 
 
-
 
NC_007973  Rmet_0673  CheA signal transduction histidine kinases  26.45 
 
 
1989 aa  71.2  0.000000000004  Cupriavidus metallidurans CH34  Bacteria  normal  0.765625  normal  0.432631 
 
 
-
 
NC_009675  Anae109_0650  response regulator receiver protein  34.17 
 
 
123 aa  71.6  0.000000000004  Anaeromyxobacter sp. Fw109-5  Bacteria  normal  0.438565  normal 
 
 
-
 
NC_007005  Psyr_1098  PAS:GGDEF  27.27 
 
 
705 aa  71.2  0.000000000005  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  normal 
 
 
-
 
NC_013730  Slin_4321  histidine kinase  31.5 
 
 
1355 aa  71.2  0.000000000005  Spirosoma linguale DSM 74  Bacteria  normal  normal  0.295286 
 
 
-
 
NC_008061  Bcen_3730  two component LuxR family transcriptional regulator  38.71 
 
 
312 aa  71.2  0.000000000005  Burkholderia cenocepacia AU 1054  Bacteria  normal  n/a   
 
 
-
 
NC_011884  Cyan7425_0790  multi-sensor signal transduction histidine kinase  32.52 
 
 
566 aa  70.9  0.000000000005  Cyanothece sp. PCC 7425  Bacteria  normal  0.391268  normal 
 
 
-
 
NC_011661  Dtur_1237  two component transcriptional regulator, winged helix family  34.4 
 
 
232 aa  71.2  0.000000000005  Dictyoglomus turgidum DSM 6724  Bacteria  normal  n/a   
 
 
-
 
NC_008543  Bcen2424_4638  two component LuxR family transcriptional regulator  38.71 
 
 
312 aa  71.2  0.000000000005  Burkholderia cenocepacia HI2424  Bacteria  normal  normal 
 
 
-
 
NC_013422  Hneap_0134  response regulator receiver protein  31.09 
 
 
123 aa  71.2  0.000000000005  Halothiobacillus neapolitanus c2  Bacteria  normal  0.81317  n/a   
 
 
-
 
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