More than 300 homologs were found in PanDaTox collection
for query gene Mesil_2092 on replicon NC_014212
Organism: Meiothermus silvanus DSM 9946



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_014212  Mesil_2092  response regulator receiver protein  100 
 
 
298 aa  600  1e-170  Meiothermus silvanus DSM 9946  Bacteria  normal  0.748601  normal 
 
 
-
 
NC_008025  Dgeo_1069  response regulator receiver protein  40.34 
 
 
128 aa  97.4  2e-19  Deinococcus geothermalis DSM 11300  Bacteria  normal  0.0511705  normal  0.476202 
 
 
-
 
NC_010531  Pnec_1772  two component transcriptional regulator, Fis family  33.03 
 
 
227 aa  85.5  9e-16  Polynucleobacter necessarius subsp. necessarius STIR1  Bacteria  normal  normal  0.979845 
 
 
-
 
NC_013739  Cwoe_5381  two component transcriptional regulator, winged helix family  37.19 
 
 
235 aa  84.7  0.000000000000002  Conexibacter woesei DSM 14684  Bacteria  normal  0.0242785  normal 
 
 
-
 
NC_011726  PCC8801_4019  response regulator receiver protein  31.62 
 
 
396 aa  81.6  0.00000000000001  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_013161  Cyan8802_4057  response regulator receiver protein  31.62 
 
 
396 aa  81.6  0.00000000000001  Cyanothece sp. PCC 8802  Bacteria  normal  normal 
 
 
-
 
NC_013061  Phep_4008  response regulator receiver  41.18 
 
 
1374 aa  81.3  0.00000000000002  Pedobacter heparinus DSM 2366  Bacteria  normal  0.702059  normal 
 
 
-
 
NC_009767  Rcas_3177  adenylate/guanylate cyclase with GAF and PAS/PAC sensors  39.34 
 
 
971 aa  81.3  0.00000000000002  Roseiflexus castenholzii DSM 13941  Bacteria  normal  normal 
 
 
-
 
NC_008554  Sfum_3211  response regulator receiver sensor signal transduction histidine kinase  31.67 
 
 
394 aa  80.9  0.00000000000002  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  normal 
 
 
-
 
NC_007947  Mfla_0181  two component, sigma54 specific, Fis family transcriptional regulator  41.6 
 
 
423 aa  80.5  0.00000000000003  Methylobacillus flagellatus KT  Bacteria  normal  decreased coverage  0.000041492 
 
 
-
 
NC_008025  Dgeo_2199  response regulator receiver/SARP domain-containing protein  31.21 
 
 
344 aa  80.5  0.00000000000003  Deinococcus geothermalis DSM 11300  Bacteria  normal  normal  0.425276 
 
 
-
 
NC_009523  RoseRS_2694  putative PAS/PAC sensor protein  38.52 
 
 
969 aa  79.3  0.00000000000006  Roseiflexus sp. RS-1  Bacteria  normal  0.0176534  normal 
 
 
-
 
NC_011729  PCC7424_3968  response regulator receiver protein  32.79 
 
 
125 aa  79.3  0.00000000000007  Cyanothece sp. PCC 7424  Bacteria  n/a    normal 
 
 
-
 
NC_008825  Mpe_A0275  putative two component response regulator transcription regulator protein  37.76 
 
 
229 aa  79.3  0.00000000000008  Methylibium petroleiphilum PM1  Bacteria  normal  0.625871  normal  0.0173821 
 
 
-
 
NC_009675  Anae109_0467  response regulator receiver protein  39.32 
 
 
124 aa  79.3  0.00000000000008  Anaeromyxobacter sp. Fw109-5  Bacteria  normal  0.117091  normal  0.827791 
 
 
-
 
NC_009379  Pnuc_2074  two component Fis family transcriptional regulator  40 
 
 
227 aa  78.6  0.0000000000001  Polynucleobacter necessarius subsp. asymbioticus QLW-P1DMWA-1  Bacteria  normal  n/a   
 
 
-
 
NC_007413  Ava_2563  periplasmic sensor hybrid histidine kinase  30.32 
 
 
935 aa  78.6  0.0000000000001  Anabaena variabilis ATCC 29413  Bacteria  normal  normal  0.851477 
 
 
-
 
NC_007651  BTH_I0135  DNA-binding response regulator  37.4 
 
 
228 aa  78.6  0.0000000000001  Burkholderia thailandensis E264  Bacteria  normal  0.719023  n/a   
 
 
-
 
NC_011831  Cagg_2626  response regulator receiver sensor signal transduction histidine kinase  27.56 
 
 
392 aa  78.6  0.0000000000001  Chloroflexus aggregans DSM 9485  Bacteria  normal  normal 
 
 
-
 
NC_012918  GM21_0758  response regulator receiver protein  32.23 
 
 
132 aa  77.8  0.0000000000002  Geobacter sp. M21  Bacteria  n/a    normal  0.0540632 
 
 
-
 
NC_011146  Gbem_0743  response regulator receiver protein  32.79 
 
 
132 aa  77.8  0.0000000000002  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_007520  Tcr_0541  two component transcriptional regulator  27.96 
 
 
230 aa  77.8  0.0000000000002  Thiomicrospira crunogena XCL-2  Bacteria  normal  n/a   
 
 
-
 
NC_009767  Rcas_3604  putative PAS/PAC sensor protein  35.24 
 
 
619 aa  77.8  0.0000000000002  Roseiflexus castenholzii DSM 13941  Bacteria  normal  normal  0.562878 
 
 
-
 
NC_011146  Gbem_2025  response regulator receiver sensor signal transduction histidine kinase  36.11 
 
 
452 aa  77.8  0.0000000000002  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_010505  Mrad2831_4812  response regulator receiver protein  31.9 
 
 
121 aa  77  0.0000000000003  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  hitchhiker  0.00197217 
 
 
-
 
NC_007404  Tbd_0216  two component transcriptional regulator  32.79 
 
 
230 aa  77  0.0000000000003  Thiobacillus denitrificans ATCC 25259  Bacteria  normal  normal  0.305183 
 
 
-
 
NC_009457  VC0395_A0568  response regulator  38.89 
 
 
368 aa  77  0.0000000000003  Vibrio cholerae O395  Bacteria  hitchhiker  0.00216047  n/a   
 
 
-
 
NC_007951  Bxe_A4409  two component Fis family transcriptional regulator  40 
 
 
229 aa  76.6  0.0000000000004  Burkholderia xenovorans LB400  Bacteria  normal  0.352798  normal 
 
 
-
 
NC_012918  GM21_2194  response regulator receiver sensor signal transduction histidine kinase  33.62 
 
 
452 aa  77  0.0000000000004  Geobacter sp. M21  Bacteria  n/a    normal  0.514859 
 
 
-
 
NC_009485  BBta_6738  response regulator receiver, CheY1  33.62 
 
 
121 aa  76.6  0.0000000000004  Bradyrhizobium sp. BTAi1  Bacteria  normal  0.079904  normal 
 
 
-
 
NC_010681  Bphyt_0316  two component transcriptional regulator, Fis family  40 
 
 
229 aa  76.6  0.0000000000005  Burkholderia phytofirmans PsJN  Bacteria  normal  normal 
 
 
-
 
NC_007908  Rfer_0566  response regulator receiver domain-containing protein  34.45 
 
 
120 aa  75.9  0.0000000000007  Rhodoferax ferrireducens T118  Bacteria  normal  n/a   
 
 
-
 
NC_013889  TK90_2268  two component, sigma54 specific, transcriptional regulator, Fis family  37.42 
 
 
459 aa  75.9  0.0000000000007  Thioalkalivibrio sp. K90mix  Bacteria  normal  hitchhiker  0.00701331 
 
 
-
 
NC_007925  RPC_4677  response regulator receiver domain-containing protein  32.76 
 
 
121 aa  75.9  0.0000000000007  Rhodopseudomonas palustris BisB18  Bacteria  normal  normal 
 
 
-
 
NC_010524  Lcho_4000  two component Fis family transcriptional regulator  40.5 
 
 
240 aa  75.9  0.0000000000007  Leptothrix cholodnii SP-6  Bacteria  n/a    hitchhiker  0.000000203773 
 
 
-
 
NC_013456  VEA_002881  response regulator  40.57 
 
 
368 aa  75.9  0.0000000000007  Vibrio sp. Ex25  Bacteria  normal  n/a   
 
 
-
 
NC_009767  Rcas_3309  response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)  36.07 
 
 
900 aa  75.9  0.0000000000008  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.269875  normal  0.342346 
 
 
-
 
NC_013730  Slin_2666  two component transcriptional regulator, AraC family  29.37 
 
 
251 aa  75.9  0.0000000000008  Spirosoma linguale DSM 74  Bacteria  normal  0.21287  normal  0.224489 
 
 
-
 
NC_009831  Ssed_2316  response regulator receiver protein  37.84 
 
 
226 aa  75.1  0.000000000001  Shewanella sediminis HAW-EB3  Bacteria  decreased coverage  0.00000147543  hitchhiker  0.000888492 
 
 
-
 
NC_009523  RoseRS_0702  response regulator receiver modulated metal dependent phosphohydrolase  34.21 
 
 
331 aa  75.5  0.000000000001  Roseiflexus sp. RS-1  Bacteria  normal  0.140022  normal 
 
 
-
 
NC_013385  Adeg_1011  two component transcriptional regulator, winged helix family  33.61 
 
 
231 aa  75.5  0.000000000001  Ammonifex degensii KC4  Bacteria  normal  n/a   
 
 
-
 
NC_008699  Noca_1865  response regulator receiver  33.59 
 
 
224 aa  75.5  0.000000000001  Nocardioides sp. JS614  Bacteria  normal  0.59899  n/a   
 
 
-
 
NC_009783  VIBHAR_03091  hypothetical protein  39.62 
 
 
368 aa  75.5  0.000000000001  Vibrio harveyi ATCC BAA-1116  Bacteria  n/a    n/a   
 
 
-
 
NC_009483  Gura_3147  response regulator receiver protein  35 
 
 
121 aa  74.3  0.000000000002  Geobacter uraniireducens Rf4  Bacteria  normal  n/a   
 
 
-
 
NC_011725  BCB4264_A3169  regulatory protein VanR  34.29 
 
 
229 aa  74.3  0.000000000002  Bacillus cereus B4264  Bacteria  normal  0.16404  n/a   
 
 
-
 
NC_010524  Lcho_1536  response regulator receiver protein  35.4 
 
 
122 aa  74.3  0.000000000002  Leptothrix cholodnii SP-6  Bacteria  n/a    normal  0.0284047 
 
 
-
 
NC_007347  Reut_A2623  response regulator receiver  33.59 
 
 
160 aa  74.3  0.000000000002  Ralstonia eutropha JMP134  Bacteria  normal  n/a   
 
 
-
 
NC_009664  Krad_3620  two component transcriptional regulator, winged helix family  33.06 
 
 
239 aa  74.7  0.000000000002  Kineococcus radiotolerans SRS30216  Bacteria  normal  0.0253056  normal  0.477246 
 
 
-
 
NC_009675  Anae109_3535  response regulator receiver protein  36.28 
 
 
134 aa  74.7  0.000000000002  Anaeromyxobacter sp. Fw109-5  Bacteria  normal  0.283754  normal  0.0368978 
 
 
-
 
NC_011884  Cyan7425_1391  response regulator receiver sensor signal transduction histidine kinase  36.67 
 
 
373 aa  74.3  0.000000000002  Cyanothece sp. PCC 7425  Bacteria  normal  0.540189  normal 
 
 
-
 
NC_008340  Mlg_0356  response regulator receiver protein  33.88 
 
 
121 aa  74.7  0.000000000002  Alkalilimnicola ehrlichii MLHE-1  Bacteria  normal  0.0780111  normal  0.957515 
 
 
-
 
NC_013385  Adeg_1897  two component transcriptional regulator, winged helix family  32.5 
 
 
229 aa  74.3  0.000000000002  Ammonifex degensii KC4  Bacteria  normal  n/a   
 
 
-
 
NC_013440  Hoch_4153  two component, sigma54 specific, transcriptional regulator, Fis family  28.79 
 
 
466 aa  74.7  0.000000000002  Haliangium ochraceum DSM 14365  Bacteria  normal  normal  0.11717 
 
 
-
 
NC_008781  Pnap_3629  two component Fis family transcriptional regulator  40 
 
 
224 aa  74.7  0.000000000002  Polaromonas naphthalenivorans CJ2  Bacteria  normal  normal  0.334527 
 
 
-
 
NC_007005  Psyr_1099  response regulator receiver  31.15 
 
 
129 aa  73.9  0.000000000003  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  normal 
 
 
-
 
NC_009253  Dred_2145  multi-sensor hybrid histidine kinase  30.97 
 
 
1271 aa  73.9  0.000000000003  Desulfotomaculum reducens MI-1  Bacteria  normal  0.152151  n/a   
 
 
-
 
NC_011662  Tmz1t_1352  response regulator receiver protein  43.12 
 
 
410 aa  73.9  0.000000000003  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_010483  TRQ2_1174  two component transcriptional regulator  31.93 
 
 
239 aa  73.9  0.000000000003  Thermotoga sp. RQ2  Bacteria  normal  0.0181894  n/a   
 
 
-
 
NC_007912  Sde_3108  response regulator receiver domain-containing protein  34.17 
 
 
120 aa  73.9  0.000000000003  Saccharophagus degradans 2-40  Bacteria  normal  normal 
 
 
-
 
NC_009616  Tmel_0843  response regulator receiver protein  33.88 
 
 
122 aa  73.6  0.000000000003  Thermosipho melanesiensis BI429  Bacteria  normal  0.774989  n/a   
 
 
-
 
NC_008340  Mlg_0355  response regulator receiver protein  30.97 
 
 
161 aa  73.9  0.000000000003  Alkalilimnicola ehrlichii MLHE-1  Bacteria  normal  0.384709  normal  0.97064 
 
 
-
 
NC_013595  Sros_2264  Serine phosphatase RsbU regulator of sigma subunit-like protein  35.04 
 
 
525 aa  73.6  0.000000000003  Streptosporangium roseum DSM 43021  Bacteria  normal  normal  0.0874374 
 
 
-
 
NC_009486  Tpet_1136  two component transcriptional regulator  31.93 
 
 
239 aa  73.9  0.000000000003  Thermotoga petrophila RKU-1  Bacteria  hitchhiker  0.000000652217  n/a   
 
 
-
 
NC_009080  BMA10247_2360  DNA-binding response regulator  39.13 
 
 
227 aa  73.6  0.000000000004  Burkholderia mallei NCTC 10247  Bacteria  normal  0.405701  n/a   
 
 
-
 
NC_011080  SNSL254_A1880  response regulator of RpoS  38.66 
 
 
337 aa  73.6  0.000000000004  Salmonella enterica subsp. enterica serovar Newport str. SL254  Bacteria  normal  0.239117  normal  0.804945 
 
 
-
 
NC_004578  PSPTO_1290  DNA-binding response regulator  34.35 
 
 
245 aa  73.6  0.000000000004  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  n/a   
 
 
-
 
NC_006348  BMA0149  DNA-binding response regulator  39.13 
 
 
227 aa  73.6  0.000000000004  Burkholderia mallei ATCC 23344  Bacteria  normal  0.0760476  n/a   
 
 
-
 
NC_007347  Reut_A3402  helix-turn-helix, Fis-type  39.13 
 
 
236 aa  73.6  0.000000000004  Ralstonia eutropha JMP134  Bacteria  normal  0.0473986  n/a   
 
 
-
 
NC_009076  BURPS1106A_0168  Fis family DNA-binding response regulator  39.13 
 
 
227 aa  73.6  0.000000000004  Burkholderia pseudomallei 1106a  Bacteria  normal  0.75283  n/a   
 
 
-
 
NC_007434  BURPS1710b_0353  DNA-binding response regulator  39.13 
 
 
227 aa  73.6  0.000000000004  Burkholderia pseudomallei 1710b  Bacteria  normal  0.450752  n/a   
 
 
-
 
NC_011083  SeHA_C1943  response regulator of RpoS  38.66 
 
 
337 aa  73.6  0.000000000004  Salmonella enterica subsp. enterica serovar Heidelberg str. SL476  Bacteria  normal  normal  0.941531 
 
 
-
 
NC_007614  Nmul_A0389  two component, sigma54 specific, Fis family transcriptional regulator  38.05 
 
 
432 aa  73.6  0.000000000004  Nitrosospira multiformis ATCC 25196  Bacteria  normal  n/a   
 
 
-
 
NC_011146  Gbem_1708  response regulator receiver modulated diguanylate cyclase/phosphodiesterase  32.48 
 
 
869 aa  73.6  0.000000000004  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_011149  SeAg_B1392  response regulator of RpoS  38.66 
 
 
337 aa  73.6  0.000000000004  Salmonella enterica subsp. enterica serovar Agona str. SL483  Bacteria  hitchhiker  0.00188361  n/a   
 
 
-
 
NC_007948  Bpro_1136  response regulator receiver domain-containing protein  33.6 
 
 
132 aa  73.6  0.000000000004  Polaromonas sp. JS666  Bacteria  normal  normal  0.638067 
 
 
-
 
NC_008836  BMA10229_A2282  DNA-binding response regulator  39.13 
 
 
227 aa  73.6  0.000000000004  Burkholderia mallei NCTC 10229  Bacteria  normal  0.0153588  n/a   
 
 
-
 
NC_007973  Rmet_3559  response regulator receiver domain-containing protein  39.37 
 
 
238 aa  73.6  0.000000000004  Cupriavidus metallidurans CH34  Bacteria  normal  0.0874597  normal 
 
 
-
 
NC_008785  BMASAVP1_A2798  DNA-binding response regulator  39.13 
 
 
227 aa  73.6  0.000000000004  Burkholderia mallei SAVP1  Bacteria  normal  n/a   
 
 
-
 
NC_011094  SeSA_A1886  response regulator of RpoS  38.66 
 
 
337 aa  73.6  0.000000000004  Salmonella enterica subsp. enterica serovar Schwarzengrund str. CVM19633  Bacteria  normal  0.0489347  normal  0.205124 
 
 
-
 
NC_009074  BURPS668_0158  Fis family DNA-binding response regulator  39.13 
 
 
227 aa  73.6  0.000000000004  Burkholderia pseudomallei 668  Bacteria  normal  0.135474  n/a   
 
 
-
 
NC_011312  VSAL_I1082  response regulator  35.78 
 
 
367 aa  73.2  0.000000000005  Aliivibrio salmonicida LFI1238  Bacteria  normal  n/a   
 
 
-
 
NC_007517  Gmet_2453  two component, sigma54 specific, Fis family transcriptional regulator  33.88 
 
 
461 aa  73.2  0.000000000005  Geobacter metallireducens GS-15  Bacteria  hitchhiker  0.0000196128  normal 
 
 
-
 
NC_002939  GSU1320  sigma-54 dependent DNA-binding response regulator  29.52 
 
 
460 aa  72.8  0.000000000006  Geobacter sulfurreducens PCA  Bacteria  normal  n/a   
 
 
-
 
NC_009976  P9211_17451  two-component response regulator  34.11 
 
 
269 aa  72.8  0.000000000006  Prochlorococcus marinus str. MIT 9211  Bacteria  normal  normal 
 
 
-
 
NC_014165  Tbis_0479  response regulator receiver modulated serine phosphatase  34.45 
 
 
529 aa  72.8  0.000000000006  Thermobispora bispora DSM 43833  Bacteria  normal  0.53029  normal 
 
 
-
 
NC_008752  Aave_4525  two component Fis family transcriptional regulator  39.13 
 
 
238 aa  72.8  0.000000000006  Acidovorax citrulli AAC00-1  Bacteria  normal  normal 
 
 
-
 
NC_010622  Bphy_0042  two component Fis family transcriptional regulator  39.13 
 
 
229 aa  72.8  0.000000000007  Burkholderia phymatum STM815  Bacteria  normal  normal 
 
 
-
 
NC_011884  Cyan7425_4868  response regulator receiver protein  35 
 
 
143 aa  72.8  0.000000000007  Cyanothece sp. PCC 7425  Bacteria  normal  normal 
 
 
-
 
NC_014165  Tbis_3089  winged helix family two component transcriptional regulator  32.23 
 
 
224 aa  72.8  0.000000000007  Thermobispora bispora DSM 43833  Bacteria  normal  0.136258  normal 
 
 
-
 
NC_008781  Pnap_0436  response regulator receiver protein  32.26 
 
 
370 aa  72.8  0.000000000007  Polaromonas naphthalenivorans CJ2  Bacteria  normal  normal 
 
 
-
 
NC_008816  A9601_18291  two-component response regulator  34.07 
 
 
248 aa  72.4  0.000000000008  Prochlorococcus marinus str. AS9601  Bacteria  normal  0.276613  n/a   
 
 
-
 
NC_009483  Gura_3143  response regulator receiver protein  32.23 
 
 
124 aa  72.4  0.000000000008  Geobacter uraniireducens Rf4  Bacteria  normal  n/a   
 
 
-
 
NC_007912  Sde_3838  response regulator receiver domain-containing protein  28.26 
 
 
234 aa  72.4  0.000000000008  Saccharophagus degradans 2-40  Bacteria  hitchhiker  0.0000539223  normal 
 
 
-
 
NC_007954  Sden_3294  response regulator receiver  36.89 
 
 
120 aa  72.4  0.000000000008  Shewanella denitrificans OS217  Bacteria  normal  n/a   
 
 
-
 
NC_013173  Dbac_0913  response regulator receiver sensor hybrid histidine kinase  40.95 
 
 
544 aa  72.4  0.000000000008  Desulfomicrobium baculatum DSM 4028  Bacteria  normal  n/a   
 
 
-
 
NC_008254  Meso_0600  CheA signal transduction histidine kinase  32.11 
 
 
706 aa  72.8  0.000000000008  Chelativorans sp. BNC1  Bacteria  normal  n/a   
 
 
-
 
NC_002947  PP_2165  response regulator  32.88 
 
 
393 aa  72.4  0.000000000009  Pseudomonas putida KT2440  Bacteria  normal  0.0249002  normal  0.813701 
 
 
-
 
NC_013440  Hoch_0280  response regulator receiver protein  33.96 
 
 
295 aa  72.4  0.000000000009  Haliangium ochraceum DSM 14365  Bacteria  normal  normal  0.932912 
 
 
-
 
NC_007604  Synpcc7942_2416  two component transcriptional regulator  36.67 
 
 
255 aa  72.4  0.000000000009  Synechococcus elongatus PCC 7942  Bacteria  normal  normal  0.0279623 
 
 
-
 
NC_011831  Cagg_0497  response regulator receiver protein  40.19 
 
 
124 aa  72.4  0.000000000009  Chloroflexus aggregans DSM 9485  Bacteria  normal  0.41839  hitchhiker  0.0000227207 
 
 
-
 
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