More than 300 homologs were found in PanDaTox collection
for query gene M446_5172 on replicon NC_010511
Organism: Methylobacterium sp. 4-46



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Replicon accession
Locus tag
Product
% identity
Alignment on query gene
Alignment on homolog gene
Length
Bit score

E-value
Organism name
Kingdom
Plasmid clonability
Plasmid unclonability p-value
Fosmid clonability
Fosmid unclonability p-value
Coverage Plot
PanDaTox homologs
Experimental validation
NC_010511  M446_5172  response regulator receiver protein  100 
 
 		 129 aa  251  2.0000000000000002e-66  Methylobacterium sp. 4-46  Bacteria  normal  0.611676  normal  0.0583946 
 
 
-
 
NC_009379  Pnuc_2074  two component Fis family transcriptional regulator  40.98 
 
 		 227 aa  85.9  2e-16  Polynucleobacter necessarius subsp. asymbioticus QLW-P1DMWA-1  Bacteria  normal  1  n/a   
 
 
-
 
NC_010531  Pnec_1772  two component transcriptional regulator, Fis family  40.98 
 
 		 227 aa  85.5  2e-16  Polynucleobacter necessarius subsp. necessarius STIR1  Bacteria  normal  1  normal  0.979845 
 
 
-
 
NC_010322  PputGB1_3548  response regulator receiver protein  41.23 
 
 		 117 aa  85.1  3e-16  Pseudomonas putida GB-1  Bacteria  normal  1  normal  0.0400953 
 
 
-
 
NC_003295  RSc0078  two component response regulator transcription regulator protein  43.33 
 
 		 239 aa  85.1  3e-16  Ralstonia solanacearum GMI1000  Bacteria  decreased coverage  0.00000511995  normal  1 
 
 
-
 
NC_012856  Rpic12D_3348  two component transcriptional regulator, Fis family  41.27 
 
 		 237 aa  85.1  3e-16  Ralstonia pickettii 12D  Bacteria  normal  1  normal  1 
 
 
-
 
NC_007973  Rmet_3559  response regulator receiver domain-containing protein  43.33 
 
 		 238 aa  85.1  3e-16  Cupriavidus metallidurans CH34  Bacteria  normal  0.0874597  normal  1 
 
 
-
 
NC_010682  Rpic_3671  two component transcriptional regulator, Fis family  41.27 
 
 		 236 aa  84.3  4e-16  Ralstonia pickettii 12J  Bacteria  normal  1  normal  1 
 
 
-
 
NC_008825  Mpe_A0671  two component LuxR family transcriptional regulator  44.54 
 
 		 333 aa  84.3  5e-16  Methylibium petroleiphilum PM1  Bacteria  normal  0.0205263  normal  1 
 
 
-
 
NC_008825  Mpe_A0275  putative two component response regulator transcription regulator protein  42.06 
 
 		 229 aa  84  7e-16  Methylibium petroleiphilum PM1  Bacteria  normal  0.625871  normal  0.0173821 
 
 
-
 
NC_002947  PP_3833  response regulator receiver protein  41.23 
 
 		 117 aa  82.8  0.000000000000001  Pseudomonas putida KT2440  Bacteria  normal  1  normal  1 
 
 
-
 
NC_007347  Reut_A3402  helix-turn-helix, Fis-type  40.83 
 
 		 236 aa  83.2  0.000000000000001  Ralstonia eutropha JMP134  Bacteria  normal  0.0473986  n/a   
 
 
-
 
NC_012791  Vapar_4238  two component transcriptional regulator, LuxR family  43.7 
 
 		 356 aa  82  0.000000000000002  Variovorax paradoxus S110  Bacteria  normal  1  n/a   
 
 
-
 
NC_007604  Synpcc7942_1221  response regulator receiver domain-containing protein  42.06 
 
 		 125 aa  82.8  0.000000000000002  Synechococcus elongatus PCC 7942  Bacteria  normal  1  normal  1 
 
 
-
 
NC_010524  Lcho_4000  two component Fis family transcriptional regulator  43.33 
 
 		 240 aa  82  0.000000000000002  Leptothrix cholodnii SP-6  Bacteria  n/a    hitchhiker  0.000000203773 
 
 
-
 
NC_008781  Pnap_3629  two component Fis family transcriptional regulator  42.52 
 
 		 224 aa  82  0.000000000000002  Polaromonas naphthalenivorans CJ2  Bacteria  normal  1  normal  0.334527 
 
 
-
 
NC_009512  Pput_1937  response regulator receiver protein  40.35 
 
 		 117 aa  82.4  0.000000000000002  Pseudomonas putida F1  Bacteria  normal  0.29733  normal  1 
 
 
-
 
NC_011884  Cyan7425_0981  two component transcriptional regulator, LuxR family  38.66 
 
 		 221 aa  82  0.000000000000003  Cyanothece sp. PCC 7425  Bacteria  normal  1  normal  0.416641 
 
 
-
 
NC_010622  Bphy_0042  two component Fis family transcriptional regulator  42.02 
 
 		 229 aa  82  0.000000000000003  Burkholderia phymatum STM815  Bacteria  normal  1  normal  1 
 
 
-
 
NC_010681  Bphyt_0316  two component transcriptional regulator, Fis family  43.8 
 
 		 229 aa  81.6  0.000000000000004  Burkholderia phytofirmans PsJN  Bacteria  normal  1  normal  1 
 
 
-
 
NC_013124  Afer_0558  two component transcriptional regulator, winged helix family  42.31 
 
 		 237 aa  81.3  0.000000000000004  Acidimicrobium ferrooxidans DSM 10331  Bacteria  normal  1  n/a   
 
 
-
 
NC_007614  Nmul_A0389  two component, sigma54 specific, Fis family transcriptional regulator  41.13 
 
 		 432 aa  80.9  0.000000000000006  Nitrosospira multiformis ATCC 25196  Bacteria  normal  1  n/a   
 
 
-
 
NC_008786  Veis_2269  two component Fis family transcriptional regulator  42.5 
 
 		 224 aa  80.9  0.000000000000006  Verminephrobacter eiseniae EF01-2  Bacteria  normal  0.606138  normal  0.860572 
 
 
-
 
NC_007951  Bxe_A4409  two component Fis family transcriptional regulator  43.33 
 
 		 229 aa  80.1  0.000000000000008  Burkholderia xenovorans LB400  Bacteria  normal  0.352798  normal  1 
 
 
-
 
NC_009080  BMA10247_2360  DNA-binding response regulator  40.83 
 
 		 227 aa  79.7  0.00000000000001  Burkholderia mallei NCTC 10247  Bacteria  normal  0.405701  n/a   
 
 
-
 
NC_006348  BMA0149  DNA-binding response regulator  40.83 
 
 		 227 aa  79.7  0.00000000000001  Burkholderia mallei ATCC 23344  Bacteria  normal  0.0760476  n/a   
 
 
-
 
NC_007005  Psyr_1099  response regulator receiver  41.82 
 
 		 129 aa  79.3  0.00000000000001  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009074  BURPS668_0158  Fis family DNA-binding response regulator  40.83 
 
 		 227 aa  79.7  0.00000000000001  Burkholderia pseudomallei 668  Bacteria  normal  0.135474  n/a   
 
 
-
 
NC_007434  BURPS1710b_0353  DNA-binding response regulator  40.83 
 
 		 227 aa  79.7  0.00000000000001  Burkholderia pseudomallei 1710b  Bacteria  normal  0.450752  n/a   
 
 
-
 
NC_009076  BURPS1106A_0168  Fis family DNA-binding response regulator  40.83 
 
 		 227 aa  79.7  0.00000000000001  Burkholderia pseudomallei 1106a  Bacteria  normal  0.75283  n/a   
 
 
-
 
NC_010501  PputW619_3202  response regulator receiver protein  40.71 
 
 		 117 aa  80.1  0.00000000000001  Pseudomonas putida W619  Bacteria  normal  0.529191  normal  1 
 
 
-
 
NC_007760  Adeh_3844  response regulator receiver domain-containing protein  41.59 
 
 		 124 aa  79.7  0.00000000000001  Anaeromyxobacter dehalogenans 2CP-C  Bacteria  normal  1  n/a   
 
 
-
 
NC_010002  Daci_0516  two component Fis family transcriptional regulator  40.83 
 
 		 223 aa  79.7  0.00000000000001  Delftia acidovorans SPH-1  Bacteria  normal  1  normal  0.0663038 
 
 
-
 
NC_010084  Bmul_3117  two component Fis family transcriptional regulator  41.67 
 
 		 233 aa  79.7  0.00000000000001  Burkholderia multivorans ATCC 17616  Bacteria  decreased coverage  0.00594667  normal  1 
 
 
-
 
NC_008836  BMA10229_A2282  DNA-binding response regulator  40.83 
 
 		 227 aa  79.7  0.00000000000001  Burkholderia mallei NCTC 10229  Bacteria  normal  0.0153588  n/a   
 
 
-
 
NC_011891  A2cp1_3985  response regulator receiver protein  42.06 
 
 		 125 aa  79.7  0.00000000000001  Anaeromyxobacter dehalogenans 2CP-1  Bacteria  normal  1  n/a   
 
 
-
 
NC_010320  Teth514_1997  two component transcriptional regulator  35.04 
 
 		 234 aa  79.7  0.00000000000001  Thermoanaerobacter sp. X514  Bacteria  hitchhiker  0.000000742772  n/a   
 
 
-
 
NC_008781  Pnap_0436  response regulator receiver protein  37.82 
 
 		 370 aa  79.3  0.00000000000001  Polaromonas naphthalenivorans CJ2  Bacteria  normal  1  normal  1 
 
 
-
 
NC_008785  BMASAVP1_A2798  DNA-binding response regulator  40.83 
 
 		 227 aa  79.7  0.00000000000001  Burkholderia mallei SAVP1  Bacteria  normal  1  n/a   
 
 
-
 
NC_013525  Tter_1494  response regulator receiver protein  38.02 
 
 		 138 aa  79.3  0.00000000000002  Thermobaculum terrenum ATCC BAA-798  Bacteria  n/a    n/a   
 
 
-
 
NC_013730  Slin_2507  two component, sigma54 specific, transcriptional regulator, Fis family  36.89 
 
 		 488 aa  78.6  0.00000000000002  Spirosoma linguale DSM 74  Bacteria  normal  1  normal  0.182398 
 
 
-
 
NC_007413  Ava_2419  response regulator receiver domain-containing protein  42.52 
 
 		 124 aa  79.3  0.00000000000002  Anabaena variabilis ATCC 29413  Bacteria  normal  0.730066  hitchhiker  0.0000120546 
 
 
-
 
NC_007484  Noc_2401  phosphate regulon transcriptional regulatory protein phoB  37.82 
 
 		 229 aa  79.3  0.00000000000002  Nitrosococcus oceani ATCC 19707  Bacteria  normal  1  n/a   
 
 
-
 
NC_007510  Bcep18194_A6471  two component Fis family transcriptional regulator  40.83 
 
 		 233 aa  79  0.00000000000002  Burkholderia sp. 383  Bacteria  normal  1  normal  1 
 
 
-
 
NC_007651  BTH_I0135  DNA-binding response regulator  40.83 
 
 		 228 aa  79  0.00000000000002  Burkholderia thailandensis E264  Bacteria  normal  0.719023  n/a   
 
 
-
 
NC_010508  Bcenmc03_3136  two component Fis family transcriptional regulator  40.83 
 
 		 233 aa  79  0.00000000000002  Burkholderia cenocepacia MC0-3  Bacteria  normal  0.230449  normal  0.232677 
 
 
-
 
NC_008060  Bcen_2506  response regulator receiver protein  40.83 
 
 		 233 aa  79  0.00000000000002  Burkholderia cenocepacia AU 1054  Bacteria  decreased coverage  0.000665817  n/a   
 
 
-
 
NC_013440  Hoch_5989  two component, sigma54 specific, transcriptional regulator, Fis family  45.38 
 
 		 459 aa  78.6  0.00000000000002  Haliangium ochraceum DSM 14365  Bacteria  normal  0.999422  normal  1 
 
 
-
 
NC_009831  Ssed_2316  response regulator receiver protein  41.96 
 
 		 226 aa  78.2  0.00000000000003  Shewanella sediminis HAW-EB3  Bacteria  decreased coverage  0.00000147543  hitchhiker  0.000888492 
 
 
-
 
NC_007413  Ava_0301  two component LuxR family transcriptional regulator  35.16 
 
 		 231 aa  78.2  0.00000000000004  Anabaena variabilis ATCC 29413  Bacteria  normal  0.54347  normal  1 
 
 
-
 
NC_010623  Bphy_4784  response regulator receiver protein  39.81 
 
 		 131 aa  77.8  0.00000000000004  Burkholderia phymatum STM815  Bacteria  normal  0.724017  normal  0.683358 
 
 
-
 
NC_011145  AnaeK_3907  response regulator receiver protein  42.06 
 
 		 125 aa  77.8  0.00000000000004  Anaeromyxobacter sp. K  Bacteria  normal  1  n/a   
 
 
-
 
NC_007298  Daro_0031  helix-turn-helix, Fis-type  41.86 
 
 		 421 aa  77.8  0.00000000000005  Dechloromonas aromatica RCB  Bacteria  normal  1  normal  0.992354 
 
 
-
 
NC_009485  BBta_6738  response regulator receiver, CheY1  34.58 
 
 		 121 aa  77.8  0.00000000000005  Bradyrhizobium sp. BTAi1  Bacteria  normal  0.079904  normal  1 
 
 
-
 
NC_011992  Dtpsy_3240  two component transcriptional regulator, Fis family  40 
 
 		 232 aa  77.8  0.00000000000005  Acidovorax ebreus TPSY  Bacteria  normal  0.450687  n/a   
 
 
-
 
NC_010551  BamMC406_3058  two component Fis family transcriptional regulator  40.34 
 
 		 233 aa  77.8  0.00000000000005  Burkholderia ambifaria MC40-6  Bacteria  normal  0.151149  normal  1 
 
 
-
 
NC_008390  Bamb_3175  response regulator receiver protein  40.34 
 
 		 233 aa  77.4  0.00000000000005  Burkholderia ambifaria AMMD  Bacteria  normal  0.320814  n/a   
 
 
-
 
NC_008782  Ajs_3891  two component Fis family transcriptional regulator  40 
 
 		 232 aa  77.8  0.00000000000005  Acidovorax sp. JS42  Bacteria  normal  1  normal  0.569436 
 
 
-
 
NC_007925  RPC_4677  response regulator receiver domain-containing protein  33.91 
 
 		 121 aa  77.4  0.00000000000006  Rhodopseudomonas palustris BisB18  Bacteria  normal  1  normal  1 
 
 
-
 
NC_008340  Mlg_0356  response regulator receiver protein  37.19 
 
 		 121 aa  77.4  0.00000000000006  Alkalilimnicola ehrlichii MLHE-1  Bacteria  normal  0.0780111  normal  0.957515 
 
 
-
 
NC_008752  Aave_4525  two component Fis family transcriptional regulator  40.34 
 
 		 238 aa  77.4  0.00000000000006  Acidovorax citrulli AAC00-1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_007604  Synpcc7942_1816  periplasmic sensor hybrid histidine kinase  48.51 
 
 		 977 aa  77  0.00000000000008  Synechococcus elongatus PCC 7942  Bacteria  normal  0.218789  normal  0.39116 
 
 
-
 
NC_007413  Ava_2563  periplasmic sensor hybrid histidine kinase  38.79 
 
 		 935 aa  76.6  0.00000000000009  Anabaena variabilis ATCC 29413  Bacteria  normal  1  normal  0.851477 
 
 
-
 
NC_009972  Haur_2358  two component transcriptional regulator  37.5 
 
 		 231 aa  76.6  0.0000000000001  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  0.0136772  n/a   
 
 
-
 
NC_007947  Mfla_0181  two component, sigma54 specific, Fis family transcriptional regulator  42.24 
 
 		 423 aa  76.6  0.0000000000001  Methylobacillus flagellatus KT  Bacteria  normal  1  decreased coverage  0.000041492 
 
 
-
 
NC_009439  Pmen_2819  response regulator receiver protein  37.5 
 
 		 562 aa  76.3  0.0000000000001  Pseudomonas mendocina ymp  Bacteria  normal  1  normal  0.0360472 
 
 
-
 
NC_011769  DvMF_1993  two component, sigma54 specific, transcriptional regulator, Fis family  37.82 
 
 		 486 aa  75.5  0.0000000000002  Desulfovibrio vulgaris str. 'Miyazaki F'  Bacteria  n/a    normal  1 
 
 
-
 
NC_013757  Gobs_1518  response regulator receiver modulated diguanylate cyclase  42.15 
 
 		 767 aa  75.9  0.0000000000002  Geodermatophilus obscurus DSM 43160  Bacteria  normal  0.0706082  n/a   
 
 
-
 
NC_013161  Cyan8802_1264  response regulator receiver protein  35.25 
 
 		 122 aa  75.9  0.0000000000002  Cyanothece sp. PCC 8802  Bacteria  normal  0.0578681  hitchhiker  0.00155192 
 
 
-
 
NC_011884  Cyan7425_3747  response regulator receiver protein  33.88 
 
 		 121 aa  75.5  0.0000000000002  Cyanothece sp. PCC 7425  Bacteria  normal  1  normal  1 
 
 
-
 
NC_012918  GM21_1834  response regulator receiver protein  35.83 
 
 		 123 aa  75.5  0.0000000000002  Geobacter sp. M21  Bacteria  n/a    hitchhiker  0.00302805 
 
 
-
 
NC_007604  Synpcc7942_1860  two component LuxR family transcriptional regulator  40.19 
 
 		 235 aa  75.5  0.0000000000002  Synechococcus elongatus PCC 7942  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009674  Bcer98_3857  response regulator receiver protein  36.44 
 
 		 122 aa  75.9  0.0000000000002  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  0.161717  n/a   
 
 
-
 
NC_010483  TRQ2_0467  response regulator receiver protein  39.81 
 
 		 122 aa  75.5  0.0000000000002  Thermotoga sp. RQ2  Bacteria  normal  1  n/a   
 
 
-
 
NC_011146  Gbem_2384  response regulator receiver protein  35.83 
 
 		 123 aa  75.9  0.0000000000002  Geobacter bemidjiensis Bem  Bacteria  normal  1  n/a   
 
 
-
 
NC_011662  Tmz1t_4083  two component, sigma54 specific, transcriptional regulator, Fis family  42.86 
 
 		 415 aa  75.5  0.0000000000002  Thauera sp. MZ1T  Bacteria  normal  1  n/a   
 
 
-
 
NC_011726  PCC8801_1234  response regulator receiver protein  35.25 
 
 		 122 aa  75.9  0.0000000000002  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_004578  PSPTO_1278  sensory box protein/response regulator  42.7 
 
 		 705 aa  75.5  0.0000000000003  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  0.517683  n/a   
 
 
-
 
NC_007005  Psyr_1098  PAS:GGDEF  38.68 
 
 		 705 aa  75.1  0.0000000000003  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  1  normal  1 
 
 
-
 
NC_011004  Rpal_0146  response regulator receiver protein  31.03 
 
 		 121 aa  75.1  0.0000000000003  Rhodopseudomonas palustris TIE-1  Bacteria  normal  1  n/a   
 
 
-
 
NC_010506  Swoo_2294  two component transcriptional regulator  39.5 
 
 		 226 aa  75.1  0.0000000000003  Shewanella woodyi ATCC 51908  Bacteria  hitchhiker  0.000876575  normal  0.575243 
 
 
-
 
NC_009620  Smed_3762  putative adenylate/guanylate cyclase  42.24 
 
 		 520 aa  75.1  0.0000000000003  Sinorhizobium medicae WSM419  Bacteria  normal  0.978534  normal  1 
 
 
-
 
NC_013385  Adeg_1011  two component transcriptional regulator, winged helix family  39.5 
 
 		 231 aa  75.1  0.0000000000003  Ammonifex degensii KC4  Bacteria  normal  1  n/a   
 
 
-
 
NC_011729  PCC7424_3993  response regulator receiver protein  35.58 
 
 		 124 aa  75.1  0.0000000000003  Cyanothece sp. PCC 7424  Bacteria  n/a    normal  0.0199898 
 
 
-
 
NC_010511  M446_2198  response regulator receiver protein  43.9 
 
 		 127 aa  75.1  0.0000000000003  Methylobacterium sp. 4-46  Bacteria  normal  0.16592  normal  0.62826 
 
 
-
 
NC_007948  Bpro_4433  two component Fis family transcriptional regulator  39.37 
 
 		 225 aa  75.1  0.0000000000003  Polaromonas sp. JS666  Bacteria  normal  0.337273  normal  1 
 
 
-
 
NC_008312  Tery_3494  response regulator receiver protein  34.13 
 
 		 180 aa  75.1  0.0000000000003  Trichodesmium erythraeum IMS101  Bacteria  normal  0.342019  normal  1 
 
 
-
 
NC_008578  Acel_1874  response regulator receiver protein  37.78 
 
 		 320 aa  75.1  0.0000000000003  Acidothermus cellulolyticus 11B  Bacteria  normal  0.420153  normal  1 
 
 
-
 
NC_007498  Pcar_2345  two component signal transduction response regulator  38.46 
 
 		 455 aa  74.7  0.0000000000004  Pelobacter carbinolicus DSM 2380  Bacteria  hitchhiker  0.00459366  n/a   
 
 
-
 
NC_011884  Cyan7425_1062  response regulator receiver protein  35.29 
 
 		 120 aa  74.7  0.0000000000004  Cyanothece sp. PCC 7425  Bacteria  normal  0.58489  hitchhiker  0.0000344775 
 
 
-
 
NC_007908  Rfer_3587  response regulator receiver domain-containing protein  43.44 
 
 		 225 aa  74.7  0.0000000000004  Rhodoferax ferrireducens T118  Bacteria  normal  0.157723  n/a   
 
 
-
 
NC_009565  TBFG_10772  two component system response transcriptional positive regulator phoP  40 
 
 		 247 aa  74.7  0.0000000000004  Mycobacterium tuberculosis F11  Bacteria  normal  1  normal  0.864575 
 
 
-
 
NC_009664  Krad_0332  response regulator receiver protein  41.88 
 
 		 806 aa  74.7  0.0000000000004  Kineococcus radiotolerans SRS30216  Bacteria  normal  0.112355  normal  0.937153 
 
 
-
 
NC_008312  Tery_4323  two component LuxR family transcriptional regulator  33.61 
 
 		 215 aa  74.7  0.0000000000004  Trichodesmium erythraeum IMS101  Bacteria  normal  0.115662  normal  0.727411 
 
 
-
 
NC_008752  Aave_3524  two component LuxR family transcriptional regulator  41.18 
 
 		 353 aa  74.7  0.0000000000004  Acidovorax citrulli AAC00-1  Bacteria  normal  0.406085  normal  0.428998 
 
 
-
 
NC_011769  DvMF_1461  two component, sigma54 specific, transcriptional regulator, Fis family  43.22 
 
 		 491 aa  74.3  0.0000000000005  Desulfovibrio vulgaris str. 'Miyazaki F'  Bacteria  n/a    normal  0.750458 
 
 
-
 
NC_007413  Ava_2150  response regulator receiver Signal transduction histidine kinase  36.21 
 
 		 443 aa  74.3  0.0000000000005  Anabaena variabilis ATCC 29413  Bacteria  normal  1  normal  0.394463 
 
 
-
 
NC_011772  BCG9842_B5493  sporulation initiation phosphotransferase F  36.44 
 
 		 122 aa  74.3  0.0000000000005  Bacillus cereus G9842  Bacteria  hitchhiker  0.0000162821  unclonable  2.17721e-26 
 
 
-
 
NC_009486  Tpet_0452  response regulator receiver protein  38.83 
 
 		 122 aa  74.3  0.0000000000005  Thermotoga petrophila RKU-1  Bacteria  normal  0.17051  n/a   
 
 
-
 
NC_011726  PCC8801_1936  two component transcriptional regulator, winged helix family  36.36 
 
 		 246 aa  73.9  0.0000000000006  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
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