More than 300 homologs were found in PanDaTox collection
for query gene Htur_2765 on replicon NC_013743
Organism: Haloterrigena turkmenica DSM 5511



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Replicon accession
Locus tag
Product
% identity
Alignment on query gene
Alignment on homolog gene
Length
Bit score

E-value
Organism name
Kingdom
Plasmid clonability
Plasmid unclonability p-value
Fosmid clonability
Fosmid unclonability p-value
Coverage Plot
PanDaTox homologs
Experimental validation
NC_013743  Htur_2765  3-isopropylmalate dehydratase, large subunit  100 
 
 		 473 aa  968    Haloterrigena turkmenica DSM 5511  Archaea  n/a    n/a   
 
 
-
 
NC_012029  Hlac_0872  isopropylmalate isomerase large subunit  82.03 
 
 		 473 aa  811    Halorubrum lacusprofundi ATCC 49239  Archaea  normal  1  normal  1 
 
 
-
 
NC_013922  Nmag_0901  3-isopropylmalate dehydratase, large subunit  92.96 
 
 		 474 aa  909    Natrialba magadii ATCC 43099  Archaea  normal  1  n/a   
 
 
-
 
NC_013158  Huta_0642  isopropylmalate isomerase large subunit  90.23 
 
 		 473 aa  886    Halorhabdus utahensis DSM 12940  Archaea  normal  1  n/a   
 
 
-
 
NC_013202  Hmuk_2656  isopropylmalate isomerase large subunit  90.47 
 
 		 473 aa  887    Halomicrobium mukohataei DSM 12286  Archaea  normal  1  normal  1 
 
 
-
 
NC_011729  PCC7424_0849  isopropylmalate isomerase large subunit  63.6 
 
 		 467 aa  632  1e-180  Cyanothece sp. PCC 7424  Bacteria  n/a    normal  0.339438 
 
 
-
 
NC_013161  Cyan8802_0214  isopropylmalate isomerase large subunit  63.6 
 
 		 468 aa  632  1e-180  Cyanothece sp. PCC 8802  Bacteria  hitchhiker  0.00986239  hitchhiker  0.0021568 
 
 
-
 
NC_011726  PCC8801_0217  isopropylmalate isomerase large subunit  63.6 
 
 		 468 aa  632  1e-180  Cyanothece sp. PCC 8801  Bacteria  n/a    n/a   
 
 
-
 
NC_011884  Cyan7425_1136  isopropylmalate isomerase large subunit  61.88 
 
 		 468 aa  611  9.999999999999999e-175  Cyanothece sp. PCC 7425  Bacteria  normal  0.638522  normal  1 
 
 
-
 
NC_007413  Ava_3967  isopropylmalate isomerase large subunit  62.1 
 
 		 467 aa  610  1e-173  Anabaena variabilis ATCC 29413  Bacteria  normal  0.177679  normal  0.0198383 
 
 
-
 
NC_007604  Synpcc7942_1898  isopropylmalate isomerase large subunit  62.88 
 
 		 468 aa  607  9.999999999999999e-173  Synechococcus elongatus PCC 7942  Bacteria  hitchhiker  0.00568531  normal  0.587637 
 
 
-
 
NC_007335  PMN2A_1622  isopropylmalate isomerase large subunit  59.79 
 
 		 469 aa  598  1e-170  Prochlorococcus marinus str. NATL2A  Bacteria  normal  1  n/a   
 
 
-
 
NC_008819  NATL1_03341  isopropylmalate isomerase large subunit  59.53 
 
 		 469 aa  598  1e-170  Prochlorococcus marinus str. NATL1A  Bacteria  normal  0.6876  normal  1 
 
 
-
 
NC_014248  Aazo_5028  3-isopropylmalate dehydratase large subunit  60.81 
 
 		 467 aa  599  1e-170  'Nostoc azollae' 0708  Bacteria  normal  0.44739  n/a   
 
 
-
 
NC_009091  P9301_02791  isopropylmalate isomerase large subunit  58.03 
 
 		 467 aa  590  1e-167  Prochlorococcus marinus str. MIT 9301  Bacteria  normal  0.0248029  n/a   
 
 
-
 
NC_014212  Mesil_1604  3-isopropylmalate dehydratase, large subunit  59.28 
 
 		 474 aa  583  1.0000000000000001e-165  Meiothermus silvanus DSM 9946  Bacteria  normal  0.135102  normal  0.0211413 
 
 
-
 
NC_009976  P9211_02821  isopropylmalate isomerase large subunit  59.74 
 
 		 471 aa  582  1.0000000000000001e-165  Prochlorococcus marinus str. MIT 9211  Bacteria  normal  1  normal  1 
 
 
-
 
NC_007516  Syncc9605_0256  isopropylmalate isomerase large subunit  58.89 
 
 		 472 aa  575  1.0000000000000001e-163  Synechococcus sp. CC9605  Bacteria  normal  0.809992  normal  1 
 
 
-
 
NC_013946  Mrub_1850  3-isopropylmalate dehydratase large subunit  58.53 
 
 		 474 aa  575  1.0000000000000001e-163  Meiothermus ruber DSM 1279  Bacteria  normal  1  normal  1 
 
 
-
 
NC_008817  P9515_02891  isopropylmalate isomerase large subunit  56.1 
 
 		 469 aa  573  1.0000000000000001e-162  Prochlorococcus marinus str. MIT 9515  Bacteria  normal  0.81083  n/a   
 
 
-
 
NC_008820  P9303_24691  isopropylmalate isomerase large subunit  58.89 
 
 		 478 aa  573  1.0000000000000001e-162  Prochlorococcus marinus str. MIT 9303  Bacteria  n/a    normal  1 
 
 
-
 
NC_008816  A9601_02781  isopropylmalate isomerase large subunit  56.96 
 
 		 468 aa  573  1.0000000000000001e-162  Prochlorococcus marinus str. AS9601  Bacteria  normal  1  n/a   
 
 
-
 
NC_014148  Plim_0323  3-isopropylmalate dehydratase, large subunit  60.91 
 
 		 468 aa  573  1.0000000000000001e-162  Planctomyces limnophilus DSM 3776  Bacteria  decreased coverage  0.000670591  n/a   
 
 
-
 
NC_007577  PMT9312_0258  isopropylmalate isomerase large subunit  57.6 
 
 		 469 aa  572  1.0000000000000001e-162  Prochlorococcus marinus str. MIT 9312  Bacteria  normal  1  n/a   
 
 
-
 
NC_007513  Syncc9902_2088  isopropylmalate isomerase large subunit  58.89 
 
 		 472 aa  558  1e-157  Synechococcus sp. CC9902  Bacteria  normal  1  n/a   
 
 
-
 
NC_010571  Oter_2680  isopropylmalate isomerase large subunit  56.72 
 
 		 472 aa  554  1e-156  Opitutus terrae PB90-1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_010655  Amuc_0666  3-isopropylmalate dehydratase, large subunit  53.88 
 
 		 470 aa  513  1e-144  Akkermansia muciniphila ATCC BAA-835  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009972  Haur_4441  isopropylmalate isomerase large subunit  53.09 
 
 		 471 aa  486  1e-136  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  1  n/a   
 
 
-
 
NC_013411  GYMC61_0861  isopropylmalate isomerase large subunit  53.42 
 
 		 471 aa  481  1e-135  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_012793  GWCH70_2591  isopropylmalate isomerase large subunit  53.19 
 
 		 471 aa  478  1e-133  Geobacillus sp. WCH70  Bacteria  hitchhiker  0.00933091  n/a   
 
 
-
 
NC_013521  Sked_11100  3-isopropylmalate dehydratase, large subunit  52.99 
 
 		 479 aa  469  1.0000000000000001e-131  Sanguibacter keddieii DSM 10542  Bacteria  normal  1  normal  1 
 
 
-
 
NC_014151  Cfla_2316  3-isopropylmalate dehydratase, large subunit  53 
 
 		 487 aa  468  1.0000000000000001e-131  Cellulomonas flavigena DSM 20109  Bacteria  normal  1  hitchhiker  0.000114053 
 
 
-
 
NC_013159  Svir_09060  3-isopropylmalate dehydratase, large subunit  52.9 
 
 		 471 aa  469  1.0000000000000001e-131  Saccharomonospora viridis DSM 43017  Bacteria  normal  0.918212  normal  1 
 
 
-
 
NC_013525  Tter_0194  3-isopropylmalate dehydratase, large subunit  53.53 
 
 		 469 aa  465  9.999999999999999e-131  Thermobaculum terrenum ATCC BAA-798  Bacteria  n/a    n/a   
 
 
-
 
NC_009484  Acry_2149  isopropylmalate isomerase large subunit  52.56 
 
 		 466 aa  465  9.999999999999999e-131  Acidiphilium cryptum JF-5  Bacteria  normal  0.754808  n/a   
 
 
-
 
NC_007333  Tfu_0626  isopropylmalate isomerase large subunit  52.59 
 
 		 465 aa  466  9.999999999999999e-131  Thermobifida fusca YX  Bacteria  normal  1  n/a   
 
 
-
 
NC_011365  Gdia_3280  isopropylmalate isomerase large subunit  51.28 
 
 		 467 aa  466  9.999999999999999e-131  Gluconacetobacter diazotrophicus PAl 5  Bacteria  normal  0.215534  normal  1 
 
 
-
 
NC_007406  Nwi_2785  isopropylmalate isomerase large subunit  53.55 
 
 		 468 aa  468  9.999999999999999e-131  Nitrobacter winogradskyi Nb-255  Bacteria  normal  0.378068  normal  1 
 
 
-
 
NC_014158  Tpau_1546  aconitate hydratase domain protein  50.11 
 
 		 488 aa  463  1e-129  Tsukamurella paurometabola DSM 20162  Bacteria  normal  0.406052  n/a   
 
 
-
 
NC_013530  Xcel_2357  3-isopropylmalate dehydratase, large subunit  52.15 
 
 		 517 aa  464  1e-129  Xylanimonas cellulosilytica DSM 15894  Bacteria  normal  1  n/a   
 
 
-
 
NC_009523  RoseRS_1961  isopropylmalate isomerase large subunit  51.05 
 
 		 474 aa  463  1e-129  Roseiflexus sp. RS-1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_008148  Rxyl_0278  isopropylmalate isomerase large subunit  52.48 
 
 		 469 aa  461  1e-129  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  1  n/a   
 
 
-
 
NC_013757  Gobs_4053  3-isopropylmalate dehydratase, large subunit  51.5 
 
 		 474 aa  462  1e-129  Geodermatophilus obscurus DSM 43160  Bacteria  normal  1  n/a   
 
 
-
 
NC_011004  Rpal_0240  isopropylmalate isomerase large subunit  52.7 
 
 		 469 aa  462  1e-129  Rhodopseudomonas palustris TIE-1  Bacteria  normal  1  n/a   
 
 
-
 
NC_011757  Mchl_4757  isopropylmalate isomerase large subunit  52.26 
 
 		 469 aa  459  9.999999999999999e-129  Methylobacterium chloromethanicum CM4  Bacteria  normal  1  normal  1 
 
 
-
 
NC_010725  Mpop_4879  isopropylmalate isomerase large subunit  52.26 
 
 		 469 aa  458  9.999999999999999e-129  Methylobacterium populi BJ001  Bacteria  normal  0.29662  normal  0.101077 
 
 
-
 
NC_011886  Achl_2256  isopropylmalate isomerase large subunit  51.17 
 
 		 484 aa  460  9.999999999999999e-129  Arthrobacter chlorophenolicus A6  Bacteria  n/a    hitchhiker  0.000000000783708 
 
 
-
 
NC_007778  RPB_0348  isopropylmalate isomerase large subunit  52.04 
 
 		 470 aa  459  9.999999999999999e-129  Rhodopseudomonas palustris HaA2  Bacteria  normal  1  normal  1 
 
 
-
 
NC_012803  Mlut_08740  3-isopropylmalate dehydratase, large subunit  50.95 
 
 		 484 aa  459  9.999999999999999e-129  Micrococcus luteus NCTC 2665  Bacteria  decreased coverage  0.000460564  n/a   
 
 
-
 
NC_007958  RPD_0504  isopropylmalate isomerase large subunit  52.04 
 
 		 470 aa  460  9.999999999999999e-129  Rhodopseudomonas palustris BisB5  Bacteria  normal  1  normal  1 
 
 
-
 
NC_012669  Bcav_1573  3-isopropylmalate dehydratase, large subunit  52.59 
 
 		 493 aa  459  9.999999999999999e-129  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.488131  normal  1 
 
 
-
 
NC_010172  Mext_4355  isopropylmalate isomerase large subunit  52.26 
 
 		 480 aa  459  9.999999999999999e-129  Methylobacterium extorquens PA1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_008541  Arth_2519  isopropylmalate isomerase large subunit  50.96 
 
 		 484 aa  459  9.999999999999999e-129  Arthrobacter sp. FB24  Bacteria  normal  0.252815  n/a   
 
 
-
 
NC_014210  Ndas_0185  3-isopropylmalate dehydratase, large subunit  52.16 
 
 		 468 aa  459  9.999999999999999e-129  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  0.08009  normal  1 
 
 
-
 
NC_013947  Snas_4999  3-isopropylmalate dehydratase large subunit  50.54 
 
 		 470 aa  456  1e-127  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  0.653294  normal  0.386887 
 
 
-
 
NC_010511  M446_0819  isopropylmalate isomerase large subunit  52.77 
 
 		 470 aa  456  1e-127  Methylobacterium sp. 4-46  Bacteria  normal  1  normal  1 
 
 
-
 
NC_007925  RPC_0227  isopropylmalate isomerase large subunit  52.04 
 
 		 473 aa  457  1e-127  Rhodopseudomonas palustris BisB18  Bacteria  normal  1  hitchhiker  0.00400027 
 
 
-
 
NC_009565  TBFG_13003  isopropylmalate isomerase large subunit  50.86 
 
 		 473 aa  455  1e-127  Mycobacterium tuberculosis F11  Bacteria  normal  1  normal  1 
 
 
-
 
NC_013235  Namu_1478  3-isopropylmalate dehydratase, large subunit  50.95 
 
 		 486 aa  456  1e-127  Nakamurella multipartita DSM 44233  Bacteria  normal  0.333411  normal  0.827202 
 
 
-
 
NC_011894  Mnod_1416  isopropylmalate isomerase large subunit  52.25 
 
 		 470 aa  456  1e-127  Methylobacterium nodulans ORS 2060  Bacteria  normal  0.941586  n/a   
 
 
-
 
NC_008699  Noca_3298  3-isopropylmalate dehydratase, large subunit  51.79 
 
 		 471 aa  456  1e-127  Nocardioides sp. JS614  Bacteria  normal  0.405916  n/a   
 
 
-
 
NC_013441  Gbro_3215  3-isopropylmalate dehydratase, large subunit  51.06 
 
 		 477 aa  456  1e-127  Gordonia bronchialis DSM 43247  Bacteria  normal  0.056695  n/a   
 
 
-
 
NC_008726  Mvan_2135  isopropylmalate isomerase large subunit  51.49 
 
 		 481 aa  457  1e-127  Mycobacterium vanbaalenii PYR-1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009767  Rcas_1549  isopropylmalate isomerase large subunit  50.64 
 
 		 472 aa  457  1e-127  Roseiflexus castenholzii DSM 13941  Bacteria  normal  0.269438  normal  0.14031 
 
 
-
 
NC_009338  Mflv_4227  isopropylmalate isomerase large subunit  51.28 
 
 		 481 aa  454  1.0000000000000001e-126  Mycobacterium gilvum PYR-GCK  Bacteria  normal  1  normal  0.888543 
 
 
-
 
NC_013172  Bfae_18560  3-isopropylmalate dehydratase, large subunit  51.72 
 
 		 479 aa  452  1.0000000000000001e-126  Brachybacterium faecium DSM 4810  Bacteria  normal  0.242112  n/a   
 
 
-
 
NC_014158  Tpau_2848  3-isopropylmalate dehydratase, large subunit  50.53 
 
 		 481 aa  452  1.0000000000000001e-126  Tsukamurella paurometabola DSM 20162  Bacteria  normal  1  n/a   
 
 
-
 
NC_010465  YPK_3537  isopropylmalate isomerase large subunit  50.64 
 
 		 476 aa  452  1.0000000000000001e-126  Yersinia pseudotuberculosis YPIII  Bacteria  normal  1  n/a   
 
 
-
 
NC_009485  BBta_0363  isopropylmalate isomerase large subunit  52.34 
 
 		 468 aa  454  1.0000000000000001e-126  Bradyrhizobium sp. BTAi1  Bacteria  normal  0.271446  normal  0.532793 
 
 
-
 
NC_007964  Nham_3584  isopropylmalate isomerase large subunit  52.7 
 
 		 468 aa  452  1.0000000000000001e-126  Nitrobacter hamburgensis X14  Bacteria  normal  0.931395  n/a   
 
 
-
 
NC_009708  YpsIP31758_3407  isopropylmalate isomerase large subunit  50.64 
 
 		 476 aa  452  1.0000000000000001e-126  Yersinia pseudotuberculosis IP 31758  Bacteria  normal  1  n/a   
 
 
-
 
NC_010159  YpAngola_A2938  isopropylmalate isomerase large subunit  50.64 
 
 		 476 aa  452  1.0000000000000001e-126  Yersinia pestis Angola  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009355  OSTLU_28677  predicted protein  52.35 
 
 		 722 aa  452  1.0000000000000001e-126  Ostreococcus lucimarinus CCE9901  Eukaryota  normal  1  n/a   
 
 
-
 
NC_009719  Plav_1423  3-isopropylmalate dehydratase, large subunit  50.11 
 
 		 473 aa  452  1.0000000000000001e-126  Parvibaculum lavamentivorans DS-1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_013131  Caci_8049  3-isopropylmalate dehydratase, large subunit  50.75 
 
 		 468 aa  453  1.0000000000000001e-126  Catenulispora acidiphila DSM 44928  Bacteria  normal  0.200463  normal  1 
 
 
-
 
NC_013132  Cpin_1982  isopropylmalate isomerase large subunit  49.46 
 
 		 465 aa  453  1.0000000000000001e-126  Chitinophaga pinensis DSM 2588  Bacteria  normal  0.211248  normal  0.733676 
 
 
-
 
BN001301  ANIA_05886  alpha isopropylmalate isomerase (Eurofung)  50.74 
 
 		 772 aa  450  1e-125  Aspergillus nidulans FGSC A4  Eukaryota  decreased coverage  0.00198619  normal  0.994666 
 
 
-
 
NC_004310  BR1906  isopropylmalate isomerase large subunit  51.72 
 
 		 469 aa  451  1e-125  Brucella suis 1330  Bacteria  normal  0.276241  n/a   
 
 
-
 
NC_013595  Sros_8018  3-isopropylmalate dehydratase, large subunit  51.84 
 
 		 459 aa  451  1e-125  Streptosporangium roseum DSM 43021  Bacteria  normal  1  normal  1 
 
 
-
 
NC_006670  CNA02270  3-isopropylmalate dehydratase, putative  49.58 
 
 		 762 aa  449  1e-125  Cryptococcus neoformans var. neoformans JEC21  Eukaryota  normal  0.0205062  n/a   
 
 
-
 
NC_009505  BOV_1834  isopropylmalate isomerase large subunit  51.72 
 
 		 469 aa  451  1e-125  Brucella ovis ATCC 25840  Bacteria  normal  0.538456  n/a   
 
 
-
 
NC_009783  VIBHAR_00815  isopropylmalate isomerase large subunit  49.78 
 
 		 466 aa  448  1e-125  Vibrio harveyi ATCC BAA-1116  Bacteria  n/a    n/a   
 
 
-
 
NC_010505  Mrad2831_0764  isopropylmalate isomerase large subunit  51.07 
 
 		 470 aa  449  1e-125  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  1  normal  0.266094 
 
 
-
 
NC_008044  TM1040_2508  isopropylmalate isomerase large subunit  52.34 
 
 		 467 aa  448  1e-125  Ruegeria sp. TM1040  Bacteria  normal  1  normal  1 
 
 
-
 
NC_008146  Mmcs_1921  isopropylmalate isomerase large subunit  50.21 
 
 		 481 aa  448  1e-125  Mycobacterium sp. MCS  Bacteria  normal  1  n/a   
 
 
-
 
NC_010085  Nmar_0422  3-isopropylmalate dehydratase large subunit  50.53 
 
 		 471 aa  451  1e-125  Nitrosopumilus maritimus SCM1  Archaea  n/a    normal  0.0695199 
 
 
-
 
NC_009077  Mjls_1901  isopropylmalate isomerase large subunit  50.74 
 
 		 481 aa  451  1e-125  Mycobacterium sp. JLS  Bacteria  normal  1  normal  0.918864 
 
 
-
 
NC_013412  GYMC61_3567  isopropylmalate isomerase large subunit  50.63 
 
 		 477 aa  449  1e-125  Geobacillus sp. Y412MC61  Bacteria  normal  1  n/a   
 
 
-
 
NC_013456  VEA_001658  3-isopropylmalate dehydratase large subunit  49.57 
 
 		 466 aa  449  1e-125  Vibrio sp. Ex25  Bacteria  normal  1  n/a   
 
 
-
 
NC_008705  Mkms_1967  isopropylmalate isomerase large subunit  50.21 
 
 		 481 aa  448  1e-125  Mycobacterium sp. KMS  Bacteria  normal  1  normal  1 
 
 
-
 
NC_013421  Pecwa_3797  isopropylmalate isomerase large subunit  50.11 
 
 		 466 aa  446  1.0000000000000001e-124  Pectobacterium wasabiae WPP163  Bacteria  normal  1  n/a   
 
 
-
 
NC_011725  BCB4264_A1455  isopropylmalate isomerase large subunit  51.4 
 
 		 464 aa  446  1.0000000000000001e-124  Bacillus cereus B4264  Bacteria  normal  1  n/a   
 
 
-
 
NC_011071  Smal_3334  3-isopropylmalate dehydratase, large subunit  49.36 
 
 		 472 aa  446  1.0000000000000001e-124  Stenotrophomonas maltophilia R551-3  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009049  Rsph17029_2523  isopropylmalate isomerase large subunit  50.86 
 
 		 475 aa  445  1.0000000000000001e-124  Rhodobacter sphaeroides ATCC 17029  Bacteria  normal  0.520601  normal  1 
 
 
-
 
NC_007643  Rru_A1189  isopropylmalate isomerase large subunit  49.57 
 
 		 472 aa  445  1.0000000000000001e-124  Rhodospirillum rubrum ATCC 11170  Bacteria  normal  0.672672  n/a   
 
 
-
 
NC_013205  Aaci_2225  3-isopropylmalate dehydratase, large subunit  53.45 
 
 		 471 aa  446  1.0000000000000001e-124  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  0.918253  n/a   
 
 
-
 
NC_013510  Tcur_3463  3-isopropylmalate dehydratase, large subunit  52.04 
 
 		 465 aa  448  1.0000000000000001e-124  Thermomonospora curvata DSM 43183  Bacteria  normal  0.0762821  n/a   
 
 
-
 
NC_012880  Dd703_0630  3-isopropylmalate dehydratase, large subunit  51.18 
 
 		 466 aa  446  1.0000000000000001e-124  Dickeya dadantii Ech703  Bacteria  normal  1  n/a   
 
 
-
 
NC_009636  Smed_3059  isopropylmalate isomerase large subunit  51.07 
 
 		 469 aa  448  1.0000000000000001e-124  Sinorhizobium medicae WSM419  Bacteria  normal  1  normal  1 
 
 
-
 
NC_008255  CHU_3742  isopropylmalate isomerase large subunit  46.87 
 
 		 466 aa  446  1.0000000000000001e-124  Cytophaga hutchinsonii ATCC 33406  Bacteria  normal  1  normal  1 
 
 
-
 
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