More than 300 homologs were found in PanDaTox collection
for query gene Hoch_3145 on replicon NC_013440
Organism: Haliangium ochraceum DSM 14365



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_013440  Hoch_3145  binding-protein-dependent transport systems inner membrane component  100 
 
 
303 aa  604  9.999999999999999e-173  Haliangium ochraceum DSM 14365  Bacteria  normal  normal  0.236219 
 
 
-
 
NC_007963  Csal_0259  binding-protein-dependent transport systems inner membrane component  67 
 
 
324 aa  418  1e-116  Chromohalobacter salexigens DSM 3043  Bacteria  normal  n/a   
 
 
-
 
NC_009668  Oant_2941  binding-protein-dependent transport systems inner membrane component  65.13 
 
 
320 aa  399  9.999999999999999e-111  Ochrobactrum anthropi ATCC 49188  Bacteria  normal  0.974377  n/a   
 
 
-
 
NC_004311  BRA0305  sugar ABC transporter, permease protein  63.82 
 
 
325 aa  397  1e-109  Brucella suis 1330  Bacteria  normal  0.0474821  n/a   
 
 
-
 
NC_009504  BOV_A0280  sugar ABC transporter, permease protein  63.82 
 
 
325 aa  396  1e-109  Brucella ovis ATCC 25840  Bacteria  normal  n/a   
 
 
-
 
NC_011368  Rleg2_5492  binding-protein-dependent transport systems inner membrane component  61.51 
 
 
328 aa  377  1e-104  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  0.511246  normal  0.17987 
 
 
-
 
NC_009620  Smed_3811  binding-protein-dependent transport systems inner membrane component  62.5 
 
 
328 aa  380  1e-104  Sinorhizobium medicae WSM419  Bacteria  normal  normal 
 
 
-
 
NC_009654  Mmwyl1_0024  binding-protein-dependent transport systems inner membrane component  59.54 
 
 
320 aa  361  1e-98  Marinomonas sp. MWYL1  Bacteria  normal  0.227719  normal  0.433481 
 
 
-
 
NC_008687  Pden_4441  binding-protein-dependent transport systems inner membrane component  59.93 
 
 
320 aa  356  1.9999999999999998e-97  Paracoccus denitrificans PD1222  Bacteria  normal  0.0272526  normal 
 
 
-
 
NC_010524  Lcho_3328  binding-protein-dependent transport systems inner membrane component  56.91 
 
 
304 aa  352  4e-96  Leptothrix cholodnii SP-6  Bacteria  n/a    normal 
 
 
-
 
NC_007005  Psyr_0761  binding-protein dependent transport system inner membrane protein  61.84 
 
 
320 aa  351  1e-95  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  0.0629996  normal  0.824676 
 
 
-
 
NC_004578  PSPTO_0888  sugar ABC transporter, permease protein  60.53 
 
 
320 aa  329  4e-89  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  0.392731  n/a   
 
 
-
 
NC_009832  Spro_2525  binding-protein-dependent transport systems inner membrane component  51.83 
 
 
330 aa  302  6.000000000000001e-81  Serratia proteamaculans 568  Bacteria  normal  normal 
 
 
-
 
NC_008025  Dgeo_0590  binding-protein-dependent transport systems inner membrane component  51.32 
 
 
315 aa  277  2e-73  Deinococcus geothermalis DSM 11300  Bacteria  normal  0.273483  normal 
 
 
-
 
NC_013525  Tter_0398  binding-protein-dependent transport systems inner membrane component  45.7 
 
 
312 aa  274  1.0000000000000001e-72  Thermobaculum terrenum ATCC BAA-798  Bacteria  n/a    n/a   
 
 
-
 
NC_009620  Smed_4397  binding-protein-dependent transport systems inner membrane component  52.57 
 
 
297 aa  260  2e-68  Sinorhizobium medicae WSM419  Bacteria  normal  normal  0.439093 
 
 
-
 
NC_013946  Mrub_2089  binding-protein-dependent transport systems inner membrane component  51.37 
 
 
293 aa  239  4e-62  Meiothermus ruber DSM 1279  Bacteria  decreased coverage  0.000000240561  normal  0.90976 
 
 
-
 
NC_009616  Tmel_1819  binding-protein-dependent transport systems inner membrane component  42.91 
 
 
293 aa  236  5.0000000000000005e-61  Thermosipho melanesiensis BI429  Bacteria  normal  0.215175  n/a   
 
 
-
 
NC_009718  Fnod_0449  binding-protein-dependent transport systems inner membrane component  41.64 
 
 
295 aa  235  6e-61  Fervidobacterium nodosum Rt17-B1  Bacteria  normal  0.982578  n/a   
 
 
-
 
NC_010483  TRQ2_0971  binding-protein-dependent transport systems inner membrane component  41.37 
 
 
293 aa  234  2.0000000000000002e-60  Thermotoga sp. RQ2  Bacteria  normal  0.0994152  n/a   
 
 
-
 
NC_009486  Tpet_0955  binding-protein-dependent transport systems inner membrane component  41.37 
 
 
293 aa  234  2.0000000000000002e-60  Thermotoga petrophila RKU-1  Bacteria  normal  n/a   
 
 
-
 
NC_010003  Pmob_0028  binding-protein-dependent transport systems inner membrane component  41.23 
 
 
300 aa  233  3e-60  Petrotoga mobilis SJ95  Bacteria  unclonable  0.0000000378352  n/a   
 
 
-
 
NC_010320  Teth514_0396  binding-protein-dependent transport systems inner membrane component  44.24 
 
 
307 aa  232  6e-60  Thermoanaerobacter sp. X514  Bacteria  normal  0.701562  n/a   
 
 
-
 
NC_008148  Rxyl_1990  binding-protein-dependent transport systems inner membrane component  41.44 
 
 
306 aa  220  1.9999999999999999e-56  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  0.306567  n/a   
 
 
-
 
NC_008541  Arth_3686  binding-protein-dependent transport systems inner membrane component  41.46 
 
 
310 aa  215  5.9999999999999996e-55  Arthrobacter sp. FB24  Bacteria  normal  n/a   
 
 
-
 
NC_011729  PCC7424_1896  binding-protein-dependent transport systems inner membrane component  38.54 
 
 
296 aa  214  1.9999999999999998e-54  Cyanothece sp. PCC 7424  Bacteria  n/a    hitchhiker  1.0543799999999999e-20 
 
 
-
 
NC_014210  Ndas_3354  binding-protein-dependent transport systems inner membrane component  39.78 
 
 
299 aa  201  1.9999999999999998e-50  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  normal 
 
 
-
 
NC_011899  Hore_20860  binding-protein-dependent transport systems inner membrane component  37.79 
 
 
357 aa  195  6e-49  Halothermothrix orenii H 168  Bacteria  normal  n/a   
 
 
-
 
NC_009664  Krad_1114  binding-protein-dependent transport systems inner membrane component  37.21 
 
 
319 aa  192  9e-48  Kineococcus radiotolerans SRS30216  Bacteria  normal  0.32149  normal  0.356013 
 
 
-
 
NC_013411  GYMC61_2958  binding-protein-dependent transport systems inner membrane component  41.46 
 
 
435 aa  189  5.999999999999999e-47  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_009664  Krad_4016  binding-protein-dependent transport systems inner membrane component  39.29 
 
 
338 aa  187  1e-46  Kineococcus radiotolerans SRS30216  Bacteria  normal  normal  0.0789775 
 
 
-
 
NC_007604  Synpcc7942_0949  permease protein of sugar ABC transporter  36.97 
 
 
292 aa  186  4e-46  Synechococcus elongatus PCC 7942  Bacteria  normal  0.688345  normal 
 
 
-
 
NC_011886  Achl_0624  binding-protein-dependent transport systems inner membrane component  41.67 
 
 
345 aa  184  2.0000000000000003e-45  Arthrobacter chlorophenolicus A6  Bacteria  n/a    normal  0.65014 
 
 
-
 
NC_012034  Athe_2309  binding-protein-dependent transport systems inner membrane component  37.1 
 
 
427 aa  183  3e-45  Anaerocellum thermophilum DSM 6725  Bacteria  hitchhiker  0.00000129291  n/a   
 
 
-
 
NC_013757  Gobs_3933  binding-protein-dependent transport systems inner membrane component  35.67 
 
 
320 aa  182  5.0000000000000004e-45  Geodermatophilus obscurus DSM 43160  Bacteria  normal  0.292649  n/a   
 
 
-
 
NC_013947  Snas_4645  binding-protein-dependent transport systems inner membrane component  36.99 
 
 
299 aa  182  8.000000000000001e-45  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  hitchhiker  0.00190071 
 
 
-
 
NC_008146  Mmcs_3982  binding-protein-dependent transport systems inner membrane component  37.8 
 
 
308 aa  180  2.9999999999999997e-44  Mycobacterium sp. MCS  Bacteria  normal  n/a   
 
 
-
 
NC_008705  Mkms_4056  binding-protein-dependent transport systems inner membrane component  37.8 
 
 
308 aa  180  2.9999999999999997e-44  Mycobacterium sp. KMS  Bacteria  normal  0.853442  normal  0.685254 
 
 
-
 
NC_012669  Bcav_1096  binding-protein-dependent transport systems inner membrane component  36.77 
 
 
315 aa  180  2.9999999999999997e-44  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.175054  normal 
 
 
-
 
NC_009338  Mflv_3852  binding-protein-dependent transport systems inner membrane component  38.13 
 
 
310 aa  180  2.9999999999999997e-44  Mycobacterium gilvum PYR-GCK  Bacteria  normal  normal  0.0634568 
 
 
-
 
NC_009077  Mjls_3996  binding-protein-dependent transport systems inner membrane component  37.8 
 
 
308 aa  179  4e-44  Mycobacterium sp. JLS  Bacteria  normal  0.172958  normal  0.378531 
 
 
-
 
NC_008726  Mvan_2543  binding-protein-dependent transport systems inner membrane component  37.87 
 
 
310 aa  178  1e-43  Mycobacterium vanbaalenii PYR-1  Bacteria  normal  0.944367  normal 
 
 
-
 
NC_013131  Caci_2623  binding-protein-dependent transport systems inner membrane component  37.15 
 
 
330 aa  177  2e-43  Catenulispora acidiphila DSM 44928  Bacteria  normal  0.0584633  normal 
 
 
-
 
NC_007484  Noc_0281  ABC transporter, inner membrane subunit  36.24 
 
 
292 aa  175  9e-43  Nitrosococcus oceani ATCC 19707  Bacteria  normal  n/a   
 
 
-
 
NC_013441  Gbro_1867  binding-protein-dependent transport systems inner membrane component  36.39 
 
 
388 aa  174  9.999999999999999e-43  Gordonia bronchialis DSM 43247  Bacteria  normal  n/a   
 
 
-
 
NC_014151  Cfla_0961  binding-protein-dependent transport systems inner membrane component  37.83 
 
 
320 aa  172  6.999999999999999e-42  Cellulomonas flavigena DSM 20109  Bacteria  normal  0.158412  hitchhiker  0.000108715 
 
 
-
 
NC_009565  TBFG_11261  sugar-transport integral membrane protein ABC transporter sugA  39.18 
 
 
307 aa  171  1e-41  Mycobacterium tuberculosis F11  Bacteria  normal  hitchhiker  0.00812399 
 
 
-
 
NC_013530  Xcel_2796  binding-protein-dependent transport systems inner membrane component  35.46 
 
 
355 aa  171  1e-41  Xylanimonas cellulosilytica DSM 15894  Bacteria  normal  n/a   
 
 
-
 
NC_008699  Noca_0870  binding-protein-dependent transport systems inner membrane component  34.69 
 
 
309 aa  171  2e-41  Nocardioides sp. JS614  Bacteria  normal  0.800905  n/a   
 
 
-
 
NC_013169  Ksed_20480  carbohydrate ABC transporter membrane protein  33.44 
 
 
318 aa  171  2e-41  Kytococcus sedentarius DSM 20547  Bacteria  normal  0.0521728  normal  0.389193 
 
 
-
 
NC_014212  Mesil_1016  binding-protein-dependent transport systems inner membrane component  36.8 
 
 
301 aa  170  3e-41  Meiothermus silvanus DSM 9946  Bacteria  normal  normal 
 
 
-
 
NC_014158  Tpau_1200  binding-protein-dependent transport systems inner membrane component  34.36 
 
 
310 aa  170  3e-41  Tsukamurella paurometabola DSM 20162  Bacteria  normal  n/a   
 
 
-
 
NC_013093  Amir_0808  binding-protein-dependent transport systems inner membrane component  35.05 
 
 
318 aa  169  4e-41  Actinosynnema mirum DSM 43827  Bacteria  normal  n/a   
 
 
-
 
NC_009832  Spro_2296  binding-protein-dependent transport systems inner membrane component  35.71 
 
 
304 aa  169  4e-41  Serratia proteamaculans 568  Bacteria  normal  0.44429  normal 
 
 
-
 
NC_008541  Arth_0414  binding-protein-dependent transport systems inner membrane component  41.7 
 
 
345 aa  167  2e-40  Arthrobacter sp. FB24  Bacteria  normal  n/a   
 
 
-
 
NC_009675  Anae109_1696  binding-protein-dependent transport systems inner membrane component  39.47 
 
 
291 aa  166  4e-40  Anaeromyxobacter sp. Fw109-5  Bacteria  hitchhiker  0.00180742  normal 
 
 
-
 
NC_011899  Hore_00790  binding-protein-dependent transport systems inner membrane component  33.33 
 
 
262 aa  165  8e-40  Halothermothrix orenii H 168  Bacteria  normal  0.772214  n/a   
 
 
-
 
NC_013205  Aaci_2236  binding-protein-dependent transport systems inner membrane component  32.38 
 
 
315 aa  164  2.0000000000000002e-39  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  n/a   
 
 
-
 
NC_010003  Pmob_0306  binding-protein-dependent transport systems inner membrane component  37.31 
 
 
294 aa  163  4.0000000000000004e-39  Petrotoga mobilis SJ95  Bacteria  normal  n/a   
 
 
-
 
NC_013159  Svir_06500  carbohydrate ABC transporter membrane protein  34.81 
 
 
321 aa  162  5.0000000000000005e-39  Saccharomonospora viridis DSM 43017  Bacteria  normal  normal 
 
 
-
 
NC_007947  Mfla_2349  binding-protein-dependent transport systems inner membrane component  37.22 
 
 
307 aa  160  3e-38  Methylobacillus flagellatus KT  Bacteria  normal  normal  0.552621 
 
 
-
 
NC_008686  Pden_1048  binding-protein-dependent transport systems inner membrane component  33.33 
 
 
308 aa  159  6e-38  Paracoccus denitrificans PD1222  Bacteria  normal  normal 
 
 
-
 
NC_012803  Mlut_04590  permease component of ABC-type sugar transporter  34.47 
 
 
323 aa  158  9e-38  Micrococcus luteus NCTC 2665  Bacteria  normal  0.359187  n/a   
 
 
-
 
NC_009921  Franean1_4616  binding-protein-dependent transport systems inner membrane component  36.2 
 
 
331 aa  158  1e-37  Frankia sp. EAN1pec  Bacteria  normal  0.338244  normal 
 
 
-
 
NC_009667  Oant_0362  binding-protein-dependent transport systems inner membrane component  34.24 
 
 
312 aa  157  3e-37  Ochrobactrum anthropi ATCC 49188  Bacteria  normal  0.541424  n/a   
 
 
-
 
NC_012669  Bcav_1681  binding-protein-dependent transport systems inner membrane component  33.45 
 
 
316 aa  156  4e-37  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.130846  normal 
 
 
-
 
NC_010320  Teth514_2196  binding-protein-dependent transport systems inner membrane component  32.63 
 
 
285 aa  154  1e-36  Thermoanaerobacter sp. X514  Bacteria  hitchhiker  0.00879782  n/a   
 
 
-
 
NC_011369  Rleg2_3122  binding-protein-dependent transport systems inner membrane component  37.69 
 
 
294 aa  154  2e-36  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  normal 
 
 
-
 
NC_009486  Tpet_0645  binding-protein-dependent transport systems inner membrane component  32.87 
 
 
309 aa  153  2.9999999999999998e-36  Thermotoga petrophila RKU-1  Bacteria  hitchhiker  0.000282921  n/a   
 
 
-
 
NC_013525  Tter_0830  binding-protein-dependent transport systems inner membrane component  30.9 
 
 
309 aa  154  2.9999999999999998e-36  Thermobaculum terrenum ATCC BAA-798  Bacteria  n/a    n/a   
 
 
-
 
NC_014213  Mesil_3227  extracellular solute-binding protein family 1  35.46 
 
 
307 aa  153  4e-36  Meiothermus silvanus DSM 9946  Bacteria  decreased coverage  0.00159401  normal  0.987884 
 
 
-
 
NC_014213  Mesil_3421  binding-protein-dependent transport systems inner membrane component  35.46 
 
 
307 aa  153  4e-36  Meiothermus silvanus DSM 9946  Bacteria  normal  0.556907  normal 
 
 
-
 
NC_012850  Rleg_3394  binding-protein-dependent transport systems inner membrane component  37.69 
 
 
294 aa  152  5e-36  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  normal  0.181077 
 
 
-
 
NC_009636  Smed_2698  binding-protein-dependent transport systems inner membrane component  32.41 
 
 
295 aa  152  5e-36  Sinorhizobium medicae WSM419  Bacteria  normal  0.0832027  normal 
 
 
-
 
NC_013947  Snas_1042  binding-protein-dependent transport systems inner membrane component  36.03 
 
 
292 aa  152  7e-36  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  0.0233696  normal  0.724909 
 
 
-
 
NC_009620  Smed_4642  binding-protein-dependent transport systems inner membrane component  30.93 
 
 
294 aa  152  7e-36  Sinorhizobium medicae WSM419  Bacteria  normal  0.288658  normal  0.0756683 
 
 
-
 
NC_010003  Pmob_0474  binding-protein-dependent transport systems inner membrane component  31.99 
 
 
291 aa  152  8e-36  Petrotoga mobilis SJ95  Bacteria  normal  n/a   
 
 
-
 
NC_011366  Rleg2_5714  binding-protein-dependent transport systems inner membrane component  35.51 
 
 
310 aa  152  8e-36  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  normal  0.568061 
 
 
-
 
NC_012848  Rleg_5336  binding-protein-dependent transport systems inner membrane component  35.14 
 
 
310 aa  151  1e-35  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  normal  0.369054 
 
 
-
 
NC_010483  TRQ2_0670  binding-protein-dependent transport systems inner membrane component  33.1 
 
 
294 aa  150  2e-35  Thermotoga sp. RQ2  Bacteria  normal  n/a   
 
 
-
 
NC_011988  Avi_6238  ABC transporter membrane spanning protein (maltose)  30.61 
 
 
294 aa  150  2e-35  Agrobacterium vitis S4  Bacteria  normal  0.602267  n/a   
 
 
-
 
NC_011894  Mnod_1414  binding-protein-dependent transport systems inner membrane component  33.8 
 
 
314 aa  150  3e-35  Methylobacterium nodulans ORS 2060  Bacteria  normal  n/a   
 
 
-
 
NC_011366  Rleg2_5689  binding-protein-dependent transport systems inner membrane component  31.33 
 
 
294 aa  150  3e-35  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  normal 
 
 
-
 
NC_007925  RPC_3645  binding-protein-dependent transport systems inner membrane component  31.92 
 
 
318 aa  149  4e-35  Rhodopseudomonas palustris BisB18  Bacteria  normal  normal  0.415839 
 
 
-
 
NC_009620  Smed_4556  binding-protein-dependent transport systems inner membrane component  37.68 
 
 
293 aa  149  5e-35  Sinorhizobium medicae WSM419  Bacteria  normal  0.357658  normal 
 
 
-
 
NC_009636  Smed_2455  binding-protein-dependent transport systems inner membrane component  31.52 
 
 
313 aa  149  7e-35  Sinorhizobium medicae WSM419  Bacteria  normal  normal 
 
 
-
 
NC_012858  Rleg_6633  binding-protein-dependent transport systems inner membrane component  31.33 
 
 
294 aa  149  8e-35  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  normal  0.61386 
 
 
-
 
NC_011899  Hore_19880  binding-protein-dependent transport systems inner membrane component  31.1 
 
 
323 aa  148  1.0000000000000001e-34  Halothermothrix orenii H 168  Bacteria  normal  n/a   
 
 
-
 
NC_013526  Tter_2000  binding-protein-dependent transport systems inner membrane component  32.62 
 
 
319 aa  147  3e-34  Thermobaculum terrenum ATCC BAA-798  Bacteria  normal  n/a   
 
 
-
 
NC_013595  Sros_5739  ABC transporter permease  31.34 
 
 
318 aa  146  3e-34  Streptosporangium roseum DSM 43021  Bacteria  normal  normal  0.184804 
 
 
-
 
NC_013595  Sros_1501  binding-protein-dependent transport systems inner membrane component  30.8 
 
 
304 aa  147  3e-34  Streptosporangium roseum DSM 43021  Bacteria  normal  normal  0.707606 
 
 
-
 
NC_011004  Rpal_3959  binding-protein-dependent transport systems inner membrane component  32 
 
 
315 aa  146  3e-34  Rhodopseudomonas palustris TIE-1  Bacteria  normal  n/a   
 
 
-
 
NC_013946  Mrub_2458  binding-protein-dependent transport systems inner membrane component  33.83 
 
 
299 aa  146  5e-34  Meiothermus ruber DSM 1279  Bacteria  normal  0.610005  normal  0.71076 
 
 
-
 
NC_010676  Bphyt_5637  binding-protein-dependent transport systems inner membrane component  32.05 
 
 
318 aa  145  8.000000000000001e-34  Burkholderia phytofirmans PsJN  Bacteria  normal  normal 
 
 
-
 
NC_009620  Smed_4329  binding-protein-dependent transport systems inner membrane component  33.66 
 
 
309 aa  145  8.000000000000001e-34  Sinorhizobium medicae WSM419  Bacteria  normal  normal  0.0434884 
 
 
-
 
NC_007778  RPB_2098  binding-protein-dependent transport systems inner membrane component  31.1 
 
 
317 aa  145  1e-33  Rhodopseudomonas palustris HaA2  Bacteria  normal  0.529199  hitchhiker  0.000478367 
 
 
-
 
NC_007958  RPD_3321  binding-protein-dependent transport systems inner membrane component  31.44 
 
 
317 aa  144  1e-33  Rhodopseudomonas palustris BisB5  Bacteria  normal  0.5641  normal 
 
 
-
 
NC_013526  Tter_2041  binding-protein-dependent transport systems inner membrane component  32.74 
 
 
305 aa  144  1e-33  Thermobaculum terrenum ATCC BAA-798  Bacteria  hitchhiker  0.00457854  n/a   
 
 
-
 
NC_011368  Rleg2_5469  binding-protein-dependent transport systems inner membrane component  32.74 
 
 
313 aa  144  1e-33  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  normal  0.394829 
 
 
-
 
NC_009953  Sare_0748  binding-protein-dependent transport systems inner membrane component  29.97 
 
 
337 aa  145  1e-33  Salinispora arenicola CNS-205  Bacteria  normal  hitchhiker  0.00168888 
 
 
-
 
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