More than 300 homologs were found in PanDaTox collection
for query gene Hneap_0785 on replicon NC_013422
Organism: Halothiobacillus neapolitanus c2



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_013422  Hneap_0785  two component transcriptional regulator, winged helix family  100 
 
 
226 aa  449  1e-125  Halothiobacillus neapolitanus c2  Bacteria  normal  n/a   
 
 
-
 
NC_009667  Oant_2666  two component transcriptional regulator  69.23 
 
 
255 aa  305  4.0000000000000004e-82  Ochrobactrum anthropi ATCC 49188  Bacteria  normal  0.128945  n/a   
 
 
-
 
NC_004310  BR0612  DNA-binding response regulator  68.47 
 
 
235 aa  304  6e-82  Brucella suis 1330  Bacteria  normal  0.688885  n/a   
 
 
-
 
NC_009505  BOV_0611  DNA-binding response regulator  68.47 
 
 
235 aa  304  6e-82  Brucella ovis ATCC 25840  Bacteria  normal  n/a   
 
 
-
 
NC_008254  Meso_0902  two component transcriptional regulator  66.97 
 
 
224 aa  300  1e-80  Chelativorans sp. BNC1  Bacteria  normal  0.375579  n/a   
 
 
-
 
NC_009720  Xaut_3517  two component transcriptional regulator  66.97 
 
 
238 aa  300  2e-80  Xanthobacter autotrophicus Py2  Bacteria  normal  0.0423488  normal  0.321822 
 
 
-
 
NC_008783  BARBAKC583_0435  DNA-binding response regulator  65.77 
 
 
228 aa  299  3e-80  Bartonella bacilliformis KC583  Bacteria  normal  n/a   
 
 
-
 
NC_010172  Mext_0329  response regulator receiver  65.5 
 
 
232 aa  295  3e-79  Methylobacterium extorquens PA1  Bacteria  normal  normal 
 
 
-
 
NC_010725  Mpop_0406  two component transcriptional regulator, winged helix family  66.52 
 
 
232 aa  294  6e-79  Methylobacterium populi BJ001  Bacteria  normal  0.076876  normal 
 
 
-
 
NC_011757  Mchl_0376  two component transcriptional regulator, winged helix family  65.5 
 
 
232 aa  294  1e-78  Methylobacterium chloromethanicum CM4  Bacteria  normal  normal 
 
 
-
 
NC_009485  BBta_3078  two component transcriptional regulator  65.02 
 
 
234 aa  293  1e-78  Bradyrhizobium sp. BTAi1  Bacteria  normal  normal 
 
 
-
 
NC_008740  Maqu_3740  two component transcriptional regulator  65.62 
 
 
226 aa  293  1e-78  Marinobacter aquaeolei VT8  Bacteria  normal  0.487084  n/a   
 
 
-
 
NC_010511  M446_0275  two component transcriptional regulator  66.67 
 
 
228 aa  293  1e-78  Methylobacterium sp. 4-46  Bacteria  normal  normal  0.0264375 
 
 
-
 
NC_011894  Mnod_5481  two component transcriptional regulator, winged helix family  66.67 
 
 
228 aa  293  2e-78  Methylobacterium nodulans ORS 2060  Bacteria  normal  0.537932  n/a   
 
 
-
 
NC_007925  RPC_1842  two component transcriptional regulator  63.68 
 
 
240 aa  292  2e-78  Rhodopseudomonas palustris BisB18  Bacteria  normal  normal 
 
 
-
 
NC_011004  Rpal_2141  two component transcriptional regulator, winged helix family  64.13 
 
 
241 aa  293  2e-78  Rhodopseudomonas palustris TIE-1  Bacteria  normal  0.316028  n/a   
 
 
-
 
NC_011666  Msil_0189  two component transcriptional regulator, winged helix family  65.18 
 
 
231 aa  290  1e-77  Methylocella silvestris BL2  Bacteria  n/a    normal  0.364869 
 
 
-
 
NC_009719  Plav_0944  two component transcriptional regulator  64.71 
 
 
225 aa  289  2e-77  Parvibaculum lavamentivorans DS-1  Bacteria  normal  0.091613  normal 
 
 
-
 
NC_010505  Mrad2831_3484  two component transcriptional regulator  65.92 
 
 
249 aa  289  2e-77  Methylobacterium radiotolerans JCM 2831  Bacteria  normal  0.524014  normal  0.179131 
 
 
-
 
NC_007958  RPD_2012  winged helix family two component transcriptional regulator  63.23 
 
 
241 aa  289  3e-77  Rhodopseudomonas palustris BisB5  Bacteria  normal  0.566736  normal  0.606644 
 
 
-
 
NC_008347  Mmar10_0943  two component transcriptional regulator  65.32 
 
 
223 aa  289  3e-77  Maricaulis maris MCS10  Bacteria  normal  0.0172896  normal  0.994999 
 
 
-
 
NC_007964  Nham_1442  two component transcriptional regulator  62.78 
 
 
230 aa  288  5.0000000000000004e-77  Nitrobacter hamburgensis X14  Bacteria  normal  n/a   
 
 
-
 
NC_007778  RPB_3442  two component transcriptional regulator  62.78 
 
 
241 aa  287  7e-77  Rhodopseudomonas palustris HaA2  Bacteria  normal  0.297648  normal  0.0871248 
 
 
-
 
NC_009484  Acry_0450  two component transcriptional regulator  65.32 
 
 
227 aa  286  2e-76  Acidiphilium cryptum JF-5  Bacteria  normal  n/a   
 
 
-
 
NC_011989  Avi_1370  two component response regulator  63.23 
 
 
252 aa  286  2e-76  Agrobacterium vitis S4  Bacteria  normal  n/a   
 
 
-
 
NC_009636  Smed_0638  two component transcriptional regulator  64.57 
 
 
233 aa  286  2e-76  Sinorhizobium medicae WSM419  Bacteria  normal  0.403787  normal  0.96994 
 
 
-
 
NC_010581  Bind_2236  two component transcriptional regulator  63.39 
 
 
227 aa  283  2.0000000000000002e-75  Beijerinckia indica subsp. indica ATCC 9039  Bacteria  normal  0.214459  normal 
 
 
-
 
NC_010623  Bphy_4527  two component transcriptional regulator  61.43 
 
 
226 aa  281  4.0000000000000003e-75  Burkholderia phymatum STM815  Bacteria  normal  normal 
 
 
-
 
NC_011369  Rleg2_0925  two component transcriptional regulator, winged helix family  62.33 
 
 
248 aa  281  4.0000000000000003e-75  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  0.0932454  normal  0.0109566 
 
 
-
 
NC_012850  Rleg_1074  two component transcriptional regulator, winged helix family  61.88 
 
 
248 aa  281  8.000000000000001e-75  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  normal  0.798214 
 
 
-
 
NC_007406  Nwi_1196  two-component transcriptional regulator  61.99 
 
 
238 aa  280  9e-75  Nitrobacter winogradskyi Nb-255  Bacteria  normal  normal 
 
 
-
 
NC_010551  BamMC406_1233  two component transcriptional regulator  61.88 
 
 
226 aa  278  4e-74  Burkholderia ambifaria MC40-6  Bacteria  normal  normal 
 
 
-
 
NC_011365  Gdia_2157  two component transcriptional regulator, winged helix family  63.68 
 
 
226 aa  278  5e-74  Gluconacetobacter diazotrophicus PAl 5  Bacteria  normal  normal 
 
 
-
 
NC_007643  Rru_A2913  two component transcriptional regulator  62.61 
 
 
227 aa  273  2.0000000000000002e-72  Rhodospirillum rubrum ATCC 11170  Bacteria  normal  0.0379396  n/a   
 
 
-
 
NC_009511  Swit_4798  two component transcriptional regulator  61.61 
 
 
230 aa  264  8e-70  Sphingomonas wittichii RW1  Bacteria  normal  normal  0.358461 
 
 
-
 
NC_010338  Caul_3888  two component transcriptional regulator  57.92 
 
 
223 aa  260  1e-68  Caulobacter sp. K31  Bacteria  normal  0.130623  normal  0.799765 
 
 
-
 
NC_011138  MADE_03339  Response regulator consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain  54.71 
 
 
226 aa  256  2e-67  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  n/a   
 
 
-
 
NC_011369  Rleg2_0704  two component transcriptional regulator, winged helix family  57.47 
 
 
227 aa  254  6e-67  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  0.205827  normal  0.593451 
 
 
-
 
NC_010002  Daci_0016  two component transcriptional regulator  55.56 
 
 
262 aa  251  5.000000000000001e-66  Delftia acidovorans SPH-1  Bacteria  normal  normal 
 
 
-
 
NC_012850  Rleg_0767  two component transcriptional regulator, winged helix family  55.2 
 
 
229 aa  249  3e-65  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  0.870104  normal 
 
 
-
 
NC_009092  Shew_0097  two component transcriptional regulator  55.66 
 
 
225 aa  246  1e-64  Shewanella loihica PV-4  Bacteria  hitchhiker  0.00144432  normal 
 
 
-
 
NC_009438  Sputcn32_0397  two component transcriptional regulator  55.66 
 
 
225 aa  245  4e-64  Shewanella putrefaciens CN-32  Bacteria  normal  n/a   
 
 
-
 
NC_007794  Saro_1599  two component transcriptional regulator  58.45 
 
 
228 aa  245  4e-64  Novosphingobium aromaticivorans DSM 12444  Bacteria  normal  0.118902  n/a   
 
 
-
 
NC_009511  Swit_4516  two component transcriptional regulator  56.11 
 
 
225 aa  245  4e-64  Sphingomonas wittichii RW1  Bacteria  normal  0.158523  normal 
 
 
-
 
NC_009997  Sbal195_0294  two component transcriptional regulator  55.66 
 
 
225 aa  244  6e-64  Shewanella baltica OS195  Bacteria  normal  normal 
 
 
-
 
NC_011986  Avi_9846  two component response regulator  54.75 
 
 
225 aa  244  6.999999999999999e-64  Agrobacterium vitis S4  Bacteria  n/a    n/a   
 
 
-
 
NC_011663  Sbal223_0298  two component transcriptional regulator, winged helix family  55.2 
 
 
225 aa  244  9e-64  Shewanella baltica OS223  Bacteria  normal  0.77813  normal 
 
 
-
 
NC_009665  Shew185_0286  two component transcriptional regulator  55.2 
 
 
225 aa  244  9e-64  Shewanella baltica OS185  Bacteria  normal  n/a   
 
 
-
 
NC_009052  Sbal_0293  two component transcriptional regulator  55.2 
 
 
225 aa  244  9e-64  Shewanella baltica OS155  Bacteria  normal  0.973428  n/a   
 
 
-
 
NC_009901  Spea_4110  two component transcriptional regulator  55.2 
 
 
225 aa  244  9.999999999999999e-64  Shewanella pealeana ATCC 700345  Bacteria  normal  n/a   
 
 
-
 
NC_009831  Ssed_4392  two component transcriptional regulator  54.75 
 
 
225 aa  243  1.9999999999999999e-63  Shewanella sediminis HAW-EB3  Bacteria  hitchhiker  0.0025821  decreased coverage  0.00000564878 
 
 
-
 
NC_004347  SO_4428  DNA-binding response regulator  55.2 
 
 
225 aa  242  3e-63  Shewanella oneidensis MR-1  Bacteria  n/a    n/a   
 
 
-
 
NC_010506  Swoo_4783  two component transcriptional regulator  54.3 
 
 
225 aa  242  3e-63  Shewanella woodyi ATCC 51908  Bacteria  hitchhiker  0.000784885  unclonable  0.00000000984925 
 
 
-
 
NC_008577  Shewana3_0282  two component transcriptional regulator  55.2 
 
 
225 aa  241  3.9999999999999997e-63  Shewanella sp. ANA-3  Bacteria  normal  0.919503  hitchhiker  0.00000025705 
 
 
-
 
NC_008321  Shewmr4_0281  two component transcriptional regulator  55.2 
 
 
225 aa  241  3.9999999999999997e-63  Shewanella sp. MR-4  Bacteria  normal  hitchhiker  0.00000001543 
 
 
-
 
NC_008322  Shewmr7_3740  two component transcriptional regulator  55.2 
 
 
225 aa  241  3.9999999999999997e-63  Shewanella sp. MR-7  Bacteria  normal  normal  0.026682 
 
 
-
 
NC_009429  Rsph17025_3971  hypothetical protein  59.19 
 
 
224 aa  241  9e-63  Rhodobacter sphaeroides ATCC 17025  Bacteria  normal  normal  0.139394 
 
 
-
 
NC_007494  RSP_3241  two-component transcriptional regulator  60.09 
 
 
224 aa  238  6.999999999999999e-62  Rhodobacter sphaeroides 2.4.1  Bacteria  normal  0.582303  n/a   
 
 
-
 
NC_009050  Rsph17029_3977  two component transcriptional regulator  60.09 
 
 
224 aa  238  6.999999999999999e-62  Rhodobacter sphaeroides ATCC 17029  Bacteria  normal  normal 
 
 
-
 
NC_009654  Mmwyl1_0419  two component transcriptional regulator  52.44 
 
 
229 aa  237  8e-62  Marinomonas sp. MWYL1  Bacteria  normal  0.509677  normal 
 
 
-
 
NC_010571  Oter_1727  two component transcriptional regulator  54.75 
 
 
228 aa  237  1e-61  Opitutus terrae PB90-1  Bacteria  normal  0.284746  normal 
 
 
-
 
NC_007954  Sden_0109  response regulator receiver  50.9 
 
 
225 aa  235  4e-61  Shewanella denitrificans OS217  Bacteria  decreased coverage  0.0000000662688  n/a   
 
 
-
 
NC_008345  Sfri_0090  two component transcriptional regulator, winged helix family protein  52.25 
 
 
227 aa  234  7e-61  Shewanella frigidimarina NCIMB 400  Bacteria  normal  n/a   
 
 
-
 
NC_007651  BTH_I0274  DNA-binding response regulator  52.91 
 
 
272 aa  233  1.0000000000000001e-60  Burkholderia thailandensis E264  Bacteria  normal  n/a   
 
 
-
 
NC_008825  Mpe_A1629  two-component response regulator  55.31 
 
 
228 aa  232  3e-60  Methylibium petroleiphilum PM1  Bacteria  normal  normal  0.128663 
 
 
-
 
NC_011365  Gdia_2950  two component transcriptional regulator, winged helix family  55.66 
 
 
258 aa  232  4.0000000000000004e-60  Gluconacetobacter diazotrophicus PAl 5  Bacteria  normal  0.0307025  normal  0.153934 
 
 
-
 
NC_010682  Rpic_1780  two component heavy metal response transcriptional regulator, winged helix family  53.6 
 
 
228 aa  232  4.0000000000000004e-60  Ralstonia pickettii 12J  Bacteria  normal  0.817023  normal  0.826624 
 
 
-
 
NC_007498  Pcar_3081  two component signal transduction response regulator  51.57 
 
 
223 aa  231  5e-60  Pelobacter carbinolicus DSM 2380  Bacteria  normal  n/a   
 
 
-
 
NC_011992  Dtpsy_2215  two component heavy metal response transcriptional regulator, winged helix family  56 
 
 
228 aa  231  6e-60  Acidovorax ebreus TPSY  Bacteria  normal  n/a   
 
 
-
 
NC_007492  Pfl01_3519  two component transcriptional regulator  50.22 
 
 
227 aa  230  1e-59  Pseudomonas fluorescens Pf0-1  Bacteria  normal  0.683413  normal  0.634912 
 
 
-
 
NC_002939  GSU0451  DNA-binding response regulator  49.78 
 
 
224 aa  229  2e-59  Geobacter sulfurreducens PCA  Bacteria  normal  0.313098  n/a   
 
 
-
 
NC_003296  RSp0655  two component response regulator transcription regulator protein  53.81 
 
 
228 aa  229  2e-59  Ralstonia solanacearum GMI1000  Bacteria  normal  normal  0.81937 
 
 
-
 
NC_010468  EcolC_3426  DNA-binding transcriptional activator CusR  49.78 
 
 
226 aa  229  2e-59  Escherichia coli ATCC 8739  Bacteria  normal  normal 
 
 
-
 
NC_007517  Gmet_3383  two component transcriptional regulator  50.22 
 
 
224 aa  229  2e-59  Geobacter metallireducens GS-15  Bacteria  normal  normal 
 
 
-
 
NC_012849  Rpic12D_5335  two component heavy metal response transcriptional regulator, winged helix family  54.05 
 
 
228 aa  228  4e-59  Ralstonia pickettii 12D  Bacteria  normal  0.733276  normal  0.970872 
 
 
-
 
NC_010682  Rpic_1718  two component heavy metal response transcriptional regulator, winged helix family  54.05 
 
 
228 aa  228  4e-59  Ralstonia pickettii 12J  Bacteria  normal  0.348336  normal 
 
 
-
 
NC_008573  Shewana3_4296  DNA-binding transcriptional activator CusR  49.78 
 
 
226 aa  228  5e-59  Shewanella sp. ANA-3  Bacteria  decreased coverage  0.0000252174  normal 
 
 
-
 
NC_009438  Sputcn32_0258  DNA-binding transcriptional activator CusR  49.78 
 
 
226 aa  228  6e-59  Shewanella putrefaciens CN-32  Bacteria  normal  n/a   
 
 
-
 
NC_010501  PputW619_2409  two component transcriptional regulator  50.9 
 
 
226 aa  228  9e-59  Pseudomonas putida W619  Bacteria  normal  0.615174  normal 
 
 
-
 
NC_002947  PP_2907  winged helix family two component transcriptional regulator  50.45 
 
 
226 aa  227  1e-58  Pseudomonas putida KT2440  Bacteria  hitchhiker  0.00514074  normal 
 
 
-
 
NC_009512  Pput_2784  two component transcriptional regulator  50.45 
 
 
226 aa  227  1e-58  Pseudomonas putida F1  Bacteria  normal  normal 
 
 
-
 
NC_010322  PputGB1_2876  two component transcriptional regulator  50.45 
 
 
226 aa  227  1e-58  Pseudomonas putida GB-1  Bacteria  normal  0.5251  normal 
 
 
-
 
NC_008554  Sfum_3674  two component transcriptional regulator  50.67 
 
 
263 aa  226  2e-58  Syntrophobacter fumaroxidans MPOB  Bacteria  normal  0.400914  normal 
 
 
-
 
NC_012849  Rpic12D_5099  two component heavy metal response transcriptional regulator, winged helix family  53.6 
 
 
228 aa  226  2e-58  Ralstonia pickettii 12D  Bacteria  normal  normal  0.0773075 
 
 
-
 
NC_004578  PSPTO_3297  DNA-binding heavy metal response regulator, putative  48.88 
 
 
227 aa  225  4e-58  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  0.441835  n/a   
 
 
-
 
NC_007005  Psyr_3127  response regulator receiver:transcriptional regulatory protein, C-terminal  48.88 
 
 
227 aa  224  1e-57  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  0.674952  normal 
 
 
-
 
NC_007298  Daro_2474  heavy metal response regulator  49.55 
 
 
223 aa  224  1e-57  Dechloromonas aromatica RCB  Bacteria  normal  normal 
 
 
-
 
NC_011313  VSAL_II0723  transcriptional regulator, response regulator  49.1 
 
 
225 aa  224  1e-57  Aliivibrio salmonicida LFI1238  Bacteria  normal  n/a   
 
 
-
 
NC_012918  GM21_3720  two component heavy metal response transcriptional regulator, winged helix family  52.23 
 
 
224 aa  223  1e-57  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_011662  Tmz1t_3985  two component heavy metal response transcriptional regulator, winged helix family  51.35 
 
 
226 aa  223  2e-57  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_010682  Rpic_1841  two component heavy metal response transcriptional regulator, winged helix family  52.7 
 
 
228 aa  223  2e-57  Ralstonia pickettii 12J  Bacteria  normal  0.99331  hitchhiker  0.00000222676 
 
 
-
 
NC_011071  Smal_2165  two component heavy metal response transcriptional regulator, winged helix family  52.25 
 
 
232 aa  223  3e-57  Stenotrophomonas maltophilia R551-3  Bacteria  normal  normal  0.77286 
 
 
-
 
NC_008062  Bcen_6011  two component transcriptional regulator  51.79 
 
 
224 aa  223  3e-57  Burkholderia cenocepacia AU 1054  Bacteria  normal  n/a   
 
 
-
 
NC_010508  Bcenmc03_2085  two component transcriptional regulator  51.79 
 
 
224 aa  223  3e-57  Burkholderia cenocepacia MC0-3  Bacteria  normal  normal 
 
 
-
 
NC_008542  Bcen2424_2066  two component transcriptional regulator  51.79 
 
 
224 aa  223  3e-57  Burkholderia cenocepacia HI2424  Bacteria  normal  n/a   
 
 
-
 
NC_011146  Gbem_0243  two component transcriptional regulator, winged helix family  48.88 
 
 
224 aa  222  4e-57  Geobacter bemidjiensis Bem  Bacteria  hitchhiker  0.000226454  n/a   
 
 
-
 
NC_010002  Daci_0451  two component heavy metal response transcriptional regulator  52.44 
 
 
230 aa  222  4e-57  Delftia acidovorans SPH-1  Bacteria  normal  normal 
 
 
-
 
NC_012918  GM21_0227  two component transcriptional regulator, winged helix family  48.88 
 
 
224 aa  221  4.9999999999999996e-57  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_007347  Reut_A2490  heavy metal response regulator  53.15 
 
 
228 aa  221  6e-57  Ralstonia eutropha JMP134  Bacteria  normal  0.289616  n/a   
 
 
-
 
NC_002939  GSU2946  DNA-binding heavy metal response regulator  51.8 
 
 
223 aa  221  7e-57  Geobacter sulfurreducens PCA  Bacteria  normal  n/a   
 
 
-
 
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