More than 300 homologs were found in PanDaTox collection
for query gene HMPREF0424_0596 on replicon NC_013721
Organism: Gardnerella vaginalis 409-05



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_013721  HMPREF0424_0596  response regulator receiver domain protein  100 
 
 
250 aa  508  1e-143  Gardnerella vaginalis 409-05  Bacteria  n/a    normal 
 
 
-
 
NC_010816  BLD_0753  putative response regulator  72.08 
 
 
240 aa  366  1e-100  Bifidobacterium longum DJO10A  Bacteria  normal  n/a   
 
 
-
 
NC_013174  Jden_1802  two component transcriptional regulator, winged helix family  62.28 
 
 
232 aa  293  1e-78  Jonesia denitrificans DSM 20603  Bacteria  normal  0.150286  normal 
 
 
-
 
NC_013530  Xcel_2485  two component transcriptional regulator, winged helix family  62.61 
 
 
243 aa  292  4e-78  Xylanimonas cellulosilytica DSM 15894  Bacteria  normal  n/a   
 
 
-
 
NC_013521  Sked_09580  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  59.24 
 
 
244 aa  281  6.000000000000001e-75  Sanguibacter keddieii DSM 10542  Bacteria  normal  normal  0.132168 
 
 
-
 
NC_012669  Bcav_1276  two component transcriptional regulator, winged helix family  57.81 
 
 
242 aa  271  7e-72  Beutenbergia cavernae DSM 12333  Bacteria  normal  normal  0.114994 
 
 
-
 
NC_009664  Krad_1230  two component transcriptional regulator, winged helix family  56.02 
 
 
254 aa  267  1e-70  Kineococcus radiotolerans SRS30216  Bacteria  normal  0.211629  normal  0.177188 
 
 
-
 
NC_013172  Bfae_19400  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  55.11 
 
 
279 aa  255  6e-67  Brachybacterium faecium DSM 4810  Bacteria  normal  0.0470356  n/a   
 
 
-
 
NC_014151  Cfla_1221  two component transcriptional regulator, winged helix family  55.65 
 
 
256 aa  249  3e-65  Cellulomonas flavigena DSM 20109  Bacteria  normal  0.655279  normal 
 
 
-
 
NC_013131  Caci_7562  two component transcriptional regulator, winged helix family  53.31 
 
 
273 aa  246  2e-64  Catenulispora acidiphila DSM 44928  Bacteria  normal  0.320599  normal 
 
 
-
 
NC_013510  Tcur_1461  two component transcriptional regulator, winged helix family  53.57 
 
 
225 aa  240  1e-62  Thermomonospora curvata DSM 43183  Bacteria  normal  0.616357  n/a   
 
 
-
 
NC_013947  Snas_5525  two component transcriptional regulator, winged helix family  53.65 
 
 
234 aa  235  4e-61  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  normal  0.997238 
 
 
-
 
NC_013093  Amir_6208  two component transcriptional regulator, winged helix family  51.33 
 
 
226 aa  227  1e-58  Actinosynnema mirum DSM 43827  Bacteria  normal  n/a   
 
 
-
 
NC_013595  Sros_1549  response regulator receiver protein  48.68 
 
 
241 aa  218  7e-56  Streptosporangium roseum DSM 43021  Bacteria  normal  0.0273908  normal 
 
 
-
 
NC_011831  Cagg_0243  two component transcriptional regulator, winged helix family  48.07 
 
 
235 aa  199  3.9999999999999996e-50  Chloroflexus aggregans DSM 9485  Bacteria  normal  0.0646165  normal 
 
 
-
 
NC_007644  Moth_0070  two component transcriptional regulator  46.02 
 
 
229 aa  194  1e-48  Moorella thermoacetica ATCC 39073  Bacteria  normal  normal  0.834843 
 
 
-
 
NC_011773  BCAH820_4704  DNA-binding response regulator PhoP  42.5 
 
 
239 aa  187  2e-46  Bacillus cereus AH820  Bacteria  n/a    hitchhiker  0.00000000000000673192 
 
 
-
 
NC_005945  BAS4484  DNA-binding response regulator PhoP  42.5 
 
 
239 aa  187  2e-46  Bacillus anthracis str. Sterne  Bacteria  normal  n/a   
 
 
-
 
NC_005957  BT9727_4319  alkaline phosphatase synthesis response regulator  42.5 
 
 
239 aa  187  2e-46  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  n/a   
 
 
-
 
NC_006274  BCZK4330  alkaline phosphatase synthesis response regulator  42.5 
 
 
239 aa  187  2e-46  Bacillus cereus E33L  Bacteria  normal  n/a   
 
 
-
 
NC_007530  GBAA_4833  DNA-binding response regulator PhoP  42.5 
 
 
239 aa  187  2e-46  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  0.0982965  n/a   
 
 
-
 
NC_013411  GYMC61_0785  two component transcriptional regulator, winged helix family  44.21 
 
 
235 aa  187  2e-46  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_011658  BCAH187_A4714  DNA-binding response regulator PhoP  42.5 
 
 
239 aa  187  2e-46  Bacillus cereus AH187  Bacteria  normal  n/a   
 
 
-
 
NC_002976  SERP1256  alkaline phosphatase synthesis transcriptional regulatory protein PhoP  43.35 
 
 
236 aa  186  4e-46  Staphylococcus epidermidis RP62A  Bacteria  normal  0.577358  n/a   
 
 
-
 
NC_003909  BCE_4720  DNA-binding response regulator PhoP  42.08 
 
 
239 aa  185  5e-46  Bacillus cereus ATCC 10987  Bacteria  normal  n/a   
 
 
-
 
NC_009972  Haur_4663  two component transcriptional regulator  43.61 
 
 
232 aa  185  7e-46  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  n/a   
 
 
-
 
NC_010184  BcerKBAB4_4419  two component transcriptional regulator  42.08 
 
 
239 aa  184  9e-46  Bacillus weihenstephanensis KBAB4  Bacteria  normal  n/a   
 
 
-
 
NC_014158  Tpau_0093  two component transcriptional regulator, winged helix family  43.91 
 
 
232 aa  183  2.0000000000000003e-45  Tsukamurella paurometabola DSM 20162  Bacteria  normal  n/a   
 
 
-
 
NC_011146  Gbem_2952  two component transcriptional regulator, winged helix family  44.74 
 
 
225 aa  183  2.0000000000000003e-45  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_011725  BCB4264_A4699  DNA-binding response regulator PhoP  42.62 
 
 
239 aa  183  3e-45  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_007912  Sde_3703  two component transcriptional regulator  42.79 
 
 
232 aa  183  3e-45  Saccharophagus degradans 2-40  Bacteria  normal  0.230236  normal  0.0884672 
 
 
-
 
NC_010184  BcerKBAB4_1215  two component transcriptional regulator  41.33 
 
 
223 aa  183  3e-45  Bacillus weihenstephanensis KBAB4  Bacteria  normal  0.533573  n/a   
 
 
-
 
NC_011772  BCG9842_B0539  DNA-binding response regulator PhoP  42.62 
 
 
239 aa  183  3e-45  Bacillus cereus G9842  Bacteria  normal  hitchhiker  0.000130788 
 
 
-
 
NC_009674  Bcer98_3274  two component transcriptional regulator  42.49 
 
 
238 aa  182  4.0000000000000006e-45  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  n/a   
 
 
-
 
NC_013501  Rmar_0987  two component transcriptional regulator, winged helix family  45.65 
 
 
233 aa  182  6e-45  Rhodothermus marinus DSM 4252  Bacteria  normal  0.195539  n/a   
 
 
-
 
NC_013947  Snas_0721  two component transcriptional regulator, winged helix family  43.17 
 
 
233 aa  182  6e-45  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  0.811558  normal 
 
 
-
 
NC_009253  Dred_0630  two component transcriptional regulator  41.03 
 
 
232 aa  182  6e-45  Desulfotomaculum reducens MI-1  Bacteria  normal  n/a   
 
 
-
 
NC_013526  Tter_2867  two component transcriptional regulator, winged helix family  44.35 
 
 
233 aa  181  1e-44  Thermobaculum terrenum ATCC BAA-798  Bacteria  normal  n/a   
 
 
-
 
NC_008148  Rxyl_2983  two component transcriptional regulator  43.86 
 
 
228 aa  181  1e-44  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  n/a   
 
 
-
 
NC_013216  Dtox_1077  two component transcriptional regulator, winged helix family  41.63 
 
 
235 aa  181  1e-44  Desulfotomaculum acetoxidans DSM 771  Bacteria  normal  normal 
 
 
-
 
NC_011725  BCB4264_A1351  DNA-binding response regulator  39.3 
 
 
223 aa  181  1e-44  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_013385  Adeg_1028  two component transcriptional regulator, winged helix family  44.25 
 
 
237 aa  180  2e-44  Ammonifex degensii KC4  Bacteria  normal  n/a   
 
 
-
 
NC_012793  GWCH70_2675  two component transcriptional regulator, winged helix family  40.77 
 
 
234 aa  180  2e-44  Geobacillus sp. WCH70  Bacteria  normal  0.661044  n/a   
 
 
-
 
NC_010718  Nther_1220  two component transcriptional regulator, winged helix family  41.38 
 
 
233 aa  180  2e-44  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  hitchhiker  0.00991602 
 
 
-
 
NC_012918  GM21_1271  two component transcriptional regulator, winged helix family  44.3 
 
 
225 aa  180  2e-44  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_011772  BCG9842_B3993  DNA-binding response regulator  39.3 
 
 
223 aa  180  2e-44  Bacillus cereus G9842  Bacteria  normal  normal  0.910988 
 
 
-
 
NC_003909  BCE_5010  DNA-binding response regulator  40.53 
 
 
232 aa  179  2.9999999999999997e-44  Bacillus cereus ATCC 10987  Bacteria  normal  n/a   
 
 
-
 
NC_006274  BCZK4605  DNA-binding response regulator  40.53 
 
 
232 aa  179  2.9999999999999997e-44  Bacillus cereus E33L  Bacteria  decreased coverage  0.000000523811  n/a   
 
 
-
 
NC_011658  BCAH187_A4991  DNA-binding response regulator  40.53 
 
 
232 aa  179  2.9999999999999997e-44  Bacillus cereus AH187  Bacteria  normal  n/a   
 
 
-
 
NC_003909  BCE_1413  DNA-binding response regulator  39.73 
 
 
223 aa  179  4e-44  Bacillus cereus ATCC 10987  Bacteria  normal  n/a   
 
 
-
 
NC_005945  BAS1213  DNA-binding response regulator  40.18 
 
 
223 aa  179  4e-44  Bacillus anthracis str. Sterne  Bacteria  normal  0.203275  n/a   
 
 
-
 
NC_006274  BCZK1193  response regulator  40.18 
 
 
223 aa  179  4e-44  Bacillus cereus E33L  Bacteria  normal  n/a   
 
 
-
 
NC_011658  BCAH187_A1453  DNA-binding response regulator  39.73 
 
 
223 aa  179  4e-44  Bacillus cereus AH187  Bacteria  normal  n/a   
 
 
-
 
NC_007530  GBAA_1312  DNA-binding response regulator  40.18 
 
 
223 aa  179  4e-44  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  n/a   
 
 
-
 
NC_011773  BCAH820_1389  DNA-binding response regulator  40.18 
 
 
223 aa  179  4e-44  Bacillus cereus AH820  Bacteria  n/a    normal 
 
 
-
 
NC_013411  GYMC61_3538  two component transcriptional regulator, winged helix family  42.31 
 
 
237 aa  179  4e-44  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_011725  BCB4264_A4980  DNA-binding response regulator  40.97 
 
 
232 aa  179  4.999999999999999e-44  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_009487  SaurJH9_1750  two component transcriptional regulator  42.31 
 
 
234 aa  179  4.999999999999999e-44  Staphylococcus aureus subsp. aureus JH9  Bacteria  normal  n/a   
 
 
-
 
NC_012793  GWCH70_1924  two component transcriptional regulator, winged helix family  42.92 
 
 
225 aa  179  4.999999999999999e-44  Geobacillus sp. WCH70  Bacteria  normal  n/a   
 
 
-
 
NC_008531  LEUM_1950  DNA-binding response regulator  41.05 
 
 
235 aa  179  4.999999999999999e-44  Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293  Bacteria  normal  0.100456  n/a   
 
 
-
 
NC_009632  SaurJH1_1784  alkaline phosphatase synthesis transcriptional regulatory protein  42.31 
 
 
234 aa  179  4.999999999999999e-44  Staphylococcus aureus subsp. aureus JH1  Bacteria  normal  0.561076  n/a   
 
 
-
 
NC_008699  Noca_3782  response regulator receiver  44.12 
 
 
297 aa  179  4.999999999999999e-44  Nocardioides sp. JS614  Bacteria  normal  n/a   
 
 
-
 
NC_012793  GWCH70_3409  two component transcriptional regulator, winged helix family  42.92 
 
 
236 aa  178  5.999999999999999e-44  Geobacillus sp. WCH70  Bacteria  normal  n/a   
 
 
-
 
NC_013205  Aaci_2570  two component transcriptional regulator, winged helix family  40.87 
 
 
239 aa  178  5.999999999999999e-44  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  n/a   
 
 
-
 
NC_005957  BT9727_1191  response regulator  39.73 
 
 
223 aa  178  5.999999999999999e-44  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  n/a   
 
 
-
 
NC_009455  DehaBAV1_0235  two component transcriptional regulator  43.61 
 
 
230 aa  178  7e-44  Dehalococcoides sp. BAV1  Bacteria  normal  n/a   
 
 
-
 
NC_009513  Lreu_0019  two component transcriptional regulator  42.49 
 
 
235 aa  178  8e-44  Lactobacillus reuteri DSM 20016  Bacteria  normal  n/a   
 
 
-
 
NC_011772  BCG9842_B0257  DNA-binding response regulator  40.53 
 
 
232 aa  178  8e-44  Bacillus cereus G9842  Bacteria  normal  0.0117449  normal 
 
 
-
 
NC_010424  Daud_1897  two component transcriptional regulator  43.04 
 
 
227 aa  178  9e-44  Candidatus Desulforudis audaxviator MP104C  Bacteria  normal  0.151466  n/a   
 
 
-
 
NC_005945  BAS4745  DNA-binding response regulator  40.09 
 
 
232 aa  177  1e-43  Bacillus anthracis str. Sterne  Bacteria  normal  n/a   
 
 
-
 
NC_005957  BT9727_4583  DNA-binding response regulator  40.09 
 
 
232 aa  177  1e-43  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  0.510578  n/a   
 
 
-
 
NC_013204  Elen_0258  two component transcriptional regulator, winged helix family  41.28 
 
 
236 aa  177  1e-43  Eggerthella lenta DSM 2243  Bacteria  normal  0.606292  normal 
 
 
-
 
NC_007530  GBAA_5106  DNA-binding response regulator  40.09 
 
 
232 aa  177  1e-43  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  n/a   
 
 
-
 
NC_008025  Dgeo_0195  two component transcriptional regulator  41.67 
 
 
222 aa  177  1e-43  Deinococcus geothermalis DSM 11300  Bacteria  normal  normal  0.304768 
 
 
-
 
NC_009767  Rcas_0353  two component transcriptional regulator  46.72 
 
 
230 aa  177  1e-43  Roseiflexus castenholzii DSM 13941  Bacteria  normal  normal  0.683455 
 
 
-
 
NC_009972  Haur_0905  two component transcriptional regulator  42.73 
 
 
238 aa  177  1e-43  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  n/a   
 
 
-
 
NC_010814  Glov_0588  two component transcriptional regulator, winged helix family  43.67 
 
 
226 aa  177  1e-43  Geobacter lovleyi SZ  Bacteria  normal  0.944339  n/a   
 
 
-
 
NC_008699  Noca_0312  response regulator receiver  41.92 
 
 
233 aa  177  1e-43  Nocardioides sp. JS614  Bacteria  normal  0.0102436  n/a   
 
 
-
 
NC_011146  Gbem_1865  two component transcriptional regulator, winged helix family  41.92 
 
 
226 aa  177  1e-43  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_002936  DET0135  DNA-binding response regulator  43.86 
 
 
230 aa  177  2e-43  Dehalococcoides ethenogenes 195  Bacteria  normal  n/a   
 
 
-
 
NC_009253  Dred_2981  two component transcriptional regulator  42.04 
 
 
229 aa  176  2e-43  Desulfotomaculum reducens MI-1  Bacteria  unclonable  0.0000000201285  n/a   
 
 
-
 
NC_011773  BCAH820_4963  DNA-binding response regulator  40.09 
 
 
232 aa  176  2e-43  Bacillus cereus AH820  Bacteria  n/a    normal 
 
 
-
 
NC_013203  Apar_1349  two component transcriptional regulator, winged helix family  40.69 
 
 
237 aa  177  2e-43  Atopobium parvulum DSM 20469  Bacteria  normal  normal  0.421984 
 
 
-
 
NC_007413  Ava_4914  two component transcriptional regulator  42.79 
 
 
238 aa  177  2e-43  Anabaena variabilis ATCC 29413  Bacteria  normal  normal  0.095278 
 
 
-
 
NC_008346  Swol_0951  response regulator receiver protein  41.63 
 
 
239 aa  177  2e-43  Syntrophomonas wolfei subsp. wolfei str. Goettingen  Bacteria  unclonable  0.0000000111905  n/a   
 
 
-
 
NC_013165  Shel_00330  response regulator with CheY-like receiver domain and winged-helix DNA-binding domain  41.35 
 
 
240 aa  177  2e-43  Slackia heliotrinireducens DSM 20476  Bacteria  decreased coverage  0.00972196  normal 
 
 
-
 
NC_009674  Bcer98_1021  two component transcriptional regulator  39.74 
 
 
223 aa  176  2e-43  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  n/a   
 
 
-
 
NC_013552  DhcVS_143  DNA-binding response regulator, two-component system, OmpR family  44.05 
 
 
256 aa  176  3e-43  Dehalococcoides sp. VS  Bacteria  normal  n/a   
 
 
-
 
NC_014230  CA2559_01810  transcriptional regulatory protein  39.29 
 
 
226 aa  176  4e-43  Croceibacter atlanticus HTCC2559  Bacteria  normal  n/a   
 
 
-
 
NC_010320  Teth514_1155  two component transcriptional regulator  40.79 
 
 
231 aa  176  4e-43  Thermoanaerobacter sp. X514  Bacteria  decreased coverage  0.000000430064  n/a   
 
 
-
 
NC_014248  Aazo_2678  winged helix family two component transcriptional regulator  42.67 
 
 
240 aa  175  5e-43  'Nostoc azollae' 0708  Bacteria  normal  n/a   
 
 
-
 
NC_013093  Amir_6310  two component transcriptional regulator, winged helix family  41.92 
 
 
261 aa  175  6e-43  Actinosynnema mirum DSM 43827  Bacteria  normal  0.534044  n/a   
 
 
-
 
NC_013170  Ccur_11690  response regulator with CheY-like receiver domain protein and winged-helix DNA-binding domain protein  42.86 
 
 
236 aa  175  7e-43  Cryptobacterium curtum DSM 15641  Bacteria  normal  0.52451  normal 
 
 
-
 
NC_013947  Snas_3904  two component transcriptional regulator, winged helix family  43.69 
 
 
230 aa  175  7e-43  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  0.144495  normal 
 
 
-
 
NC_010320  Teth514_0766  two component transcriptional regulator  40.17 
 
 
231 aa  174  8e-43  Thermoanaerobacter sp. X514  Bacteria  normal  0.585906  n/a   
 
 
-
 
NC_011831  Cagg_2709  two component transcriptional regulator, winged helix family  43.4 
 
 
236 aa  175  8e-43  Chloroflexus aggregans DSM 9485  Bacteria  decreased coverage  0.0011921  normal 
 
 
-
 
NC_013595  Sros_0132  response regulator receiver protein  42.54 
 
 
231 aa  174  8e-43  Streptosporangium roseum DSM 43021  Bacteria  normal  normal 
 
 
-
 
NC_010180  BcerKBAB4_5511  two component transcriptional regulator  40.87 
 
 
236 aa  174  9e-43  Bacillus weihenstephanensis KBAB4  Bacteria  normal  normal  0.567595 
 
 
-
 
NC_013441  Gbro_4233  response regulator receiver  44.44 
 
 
244 aa  174  9.999999999999999e-43  Gordonia bronchialis DSM 43247  Bacteria  normal  n/a   
 
 
-
 
NC_008541  Arth_1441  two component transcriptional regulator  40.08 
 
 
247 aa  174  9.999999999999999e-43  Arthrobacter sp. FB24  Bacteria  normal  0.167327  n/a   
 
 
-
 
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