More than 300 homologs were found in PanDaTox collection
for query gene Franean1_1897 on replicon NC_009921
Organism: Frankia sp. EAN1pec



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_009921  Franean1_1897  binding-protein-dependent transport systems inner membrane component  100 
 
 
285 aa  557  1e-158  Frankia sp. EAN1pec  Bacteria  normal  0.686039  normal 
 
 
-
 
NC_007777  Francci3_2254  binding-protein-dependent transport systems inner membrane component  72.08 
 
 
275 aa  365  1e-100  Frankia sp. CcI3  Bacteria  decreased coverage  0.000539502  hitchhiker  0.00573308 
 
 
-
 
NC_007644  Moth_1482  binding-protein dependent transport system inner membrane protein  39.76 
 
 
272 aa  192  4e-48  Moorella thermoacetica ATCC 39073  Bacteria  hitchhiker  0.00114182  normal 
 
 
-
 
NC_007777  Francci3_2838  binding-protein-dependent transport systems inner membrane component  39.25 
 
 
276 aa  186  3e-46  Frankia sp. CcI3  Bacteria  normal  normal  0.314351 
 
 
-
 
NC_009921  Franean1_3946  binding-protein-dependent transport systems inner membrane component  37.22 
 
 
297 aa  173  1.9999999999999998e-42  Frankia sp. EAN1pec  Bacteria  normal  normal  0.0330031 
 
 
-
 
NC_008699  Noca_4633  binding-protein-dependent transport systems inner membrane component  36.8 
 
 
275 aa  167  2.9999999999999998e-40  Nocardioides sp. JS614  Bacteria  normal  0.326622  n/a   
 
 
-
 
NC_013595  Sros_7693  putative transmembrane permease component of ABC transporter  36.5 
 
 
286 aa  157  3e-37  Streptosporangium roseum DSM 43021  Bacteria  normal  normal  0.673988 
 
 
-
 
NC_014210  Ndas_1083  binding-protein-dependent transport systems inner membrane component  34.98 
 
 
301 aa  155  6e-37  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  0.521844  normal  0.416861 
 
 
-
 
NC_014212  Mesil_0956  binding-protein-dependent transport systems inner membrane component  37.55 
 
 
286 aa  152  5e-36  Meiothermus silvanus DSM 9946  Bacteria  normal  normal  0.143013 
 
 
-
 
NC_011899  Hore_20610  binding-protein-dependent transport systems inner membrane component  33.84 
 
 
273 aa  151  1e-35  Halothermothrix orenii H 168  Bacteria  normal  n/a   
 
 
-
 
NC_014210  Ndas_0754  binding-protein-dependent transport systems inner membrane component  35.74 
 
 
289 aa  150  2e-35  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  0.467109  normal 
 
 
-
 
NC_007413  Ava_2748  binding-protein dependent transport system inner membrane protein  35.5 
 
 
306 aa  150  3e-35  Anabaena variabilis ATCC 29413  Bacteria  normal  0.925228  normal  0.18236 
 
 
-
 
NC_013131  Caci_4318  binding-protein-dependent transport systems inner membrane component  33.97 
 
 
295 aa  149  5e-35  Catenulispora acidiphila DSM 44928  Bacteria  normal  0.574995  hitchhiker  0.00173435 
 
 
-
 
NC_011886  Achl_0497  binding-protein-dependent transport systems inner membrane component  30.85 
 
 
306 aa  149  5e-35  Arthrobacter chlorophenolicus A6  Bacteria  n/a    hitchhiker  0.000825086 
 
 
-
 
NC_013521  Sked_18870  carbohydrate ABC transporter membrane protein  33.79 
 
 
319 aa  149  6e-35  Sanguibacter keddieii DSM 10542  Bacteria  normal  0.858818  normal  0.355174 
 
 
-
 
NC_013205  Aaci_0794  binding-protein-dependent transport systems inner membrane component  30.8 
 
 
273 aa  147  1.0000000000000001e-34  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  0.256296  n/a   
 
 
-
 
NC_014212  Mesil_2464  binding-protein-dependent transport systems inner membrane component  33.08 
 
 
270 aa  148  1.0000000000000001e-34  Meiothermus silvanus DSM 9946  Bacteria  normal  0.668515  normal  0.267306 
 
 
-
 
NC_013521  Sked_07090  carbohydrate ABC transporter membrane protein  33.33 
 
 
297 aa  147  3e-34  Sanguibacter keddieii DSM 10542  Bacteria  normal  0.484771  normal 
 
 
-
 
NC_013131  Caci_3806  binding-protein-dependent transport systems inner membrane component  32.16 
 
 
300 aa  145  6e-34  Catenulispora acidiphila DSM 44928  Bacteria  normal  normal 
 
 
-
 
NC_013530  Xcel_2536  binding-protein-dependent transport systems inner membrane component  31.73 
 
 
306 aa  145  7.0000000000000006e-34  Xylanimonas cellulosilytica DSM 15894  Bacteria  normal  0.250656  n/a   
 
 
-
 
NC_013946  Mrub_0043  binding-protein-dependent transport systems inner membrane component  32.32 
 
 
270 aa  145  9e-34  Meiothermus ruber DSM 1279  Bacteria  normal  normal 
 
 
-
 
NC_011981  Avi_7591  ABC transporter membrane spanning protein  31.48 
 
 
275 aa  144  1e-33  Agrobacterium vitis S4  Bacteria  normal  n/a   
 
 
-
 
NC_012669  Bcav_0017  binding-protein-dependent transport systems inner membrane component  34.22 
 
 
300 aa  144  1e-33  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.385749  normal 
 
 
-
 
NC_009565  TBFG_12849  sn-glycerol-3-phosphate transport integral membrane protein ABC transporter ugpE  32.59 
 
 
275 aa  144  2e-33  Mycobacterium tuberculosis F11  Bacteria  hitchhiker  0.00000000000144305  normal 
 
 
-
 
NC_013205  Aaci_2048  binding-protein-dependent transport systems inner membrane component  30.42 
 
 
268 aa  143  3e-33  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446  Bacteria  normal  0.353997  n/a   
 
 
-
 
NC_013595  Sros_2192  putative sugar ABC transporter, permease protein  31.91 
 
 
283 aa  143  4e-33  Streptosporangium roseum DSM 43021  Bacteria  normal  normal 
 
 
-
 
NC_011886  Achl_2662  binding-protein-dependent transport systems inner membrane component  34.1 
 
 
304 aa  143  4e-33  Arthrobacter chlorophenolicus A6  Bacteria  n/a    normal 
 
 
-
 
NC_013521  Sked_14810  carbohydrate ABC transporter membrane protein  29.63 
 
 
305 aa  142  4e-33  Sanguibacter keddieii DSM 10542  Bacteria  normal  normal  0.0148237 
 
 
-
 
NC_009616  Tmel_0751  binding-protein-dependent transport systems inner membrane component  30.59 
 
 
277 aa  142  5e-33  Thermosipho melanesiensis BI429  Bacteria  normal  n/a   
 
 
-
 
NC_012793  GWCH70_1391  binding-protein-dependent transport systems inner membrane component  31.3 
 
 
270 aa  142  6e-33  Geobacillus sp. WCH70  Bacteria  normal  n/a   
 
 
-
 
NC_012034  Athe_0401  binding-protein-dependent transport systems inner membrane component  30.86 
 
 
277 aa  142  7e-33  Anaerocellum thermophilum DSM 6725  Bacteria  unclonable  0.000000000457855  n/a   
 
 
-
 
NC_013739  Cwoe_4881  binding-protein-dependent transport systems inner membrane component  34.85 
 
 
295 aa  142  9e-33  Conexibacter woesei DSM 14684  Bacteria  normal  0.48115  normal 
 
 
-
 
NC_013530  Xcel_2649  binding-protein-dependent transport systems inner membrane component  31.09 
 
 
300 aa  141  9.999999999999999e-33  Xylanimonas cellulosilytica DSM 15894  Bacteria  normal  n/a   
 
 
-
 
NC_013172  Bfae_29880  carbohydrate ABC transporter membrane protein  34.81 
 
 
304 aa  141  9.999999999999999e-33  Brachybacterium faecium DSM 4810  Bacteria  normal  n/a   
 
 
-
 
NC_013517  Sterm_4035  binding-protein-dependent transport systems inner membrane component  25.95 
 
 
275 aa  140  3e-32  Sebaldella termitidis ATCC 33386  Bacteria  normal  n/a   
 
 
-
 
NC_013093  Amir_0972  binding-protein-dependent transport systems inner membrane component  31.84 
 
 
276 aa  140  3e-32  Actinosynnema mirum DSM 43827  Bacteria  normal  n/a   
 
 
-
 
NC_009664  Krad_0296  binding-protein-dependent transport systems inner membrane component  35.42 
 
 
301 aa  140  3e-32  Kineococcus radiotolerans SRS30216  Bacteria  normal  normal  0.0210527 
 
 
-
 
NC_013721  HMPREF0424_1289  ABC transporter, permease protein  31.1 
 
 
303 aa  140  3e-32  Gardnerella vaginalis 409-05  Bacteria  n/a    normal 
 
 
-
 
NC_010001  Cphy_1391  binding-protein-dependent transport systems inner membrane component  31.64 
 
 
276 aa  140  3e-32  Clostridium phytofermentans ISDg  Bacteria  normal  0.0775264  n/a   
 
 
-
 
NC_007778  RPB_0175  binding-protein dependent transport system inner membrane protein  30.11 
 
 
278 aa  139  3.9999999999999997e-32  Rhodopseudomonas palustris HaA2  Bacteria  normal  0.419307  normal 
 
 
-
 
NC_014210  Ndas_2035  binding-protein-dependent transport systems inner membrane component  31.95 
 
 
291 aa  139  3.9999999999999997e-32  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  0.0974901  normal  0.381629 
 
 
-
 
NC_007958  RPD_3150  binding-protein-dependent transport systems inner membrane component  30.11 
 
 
278 aa  139  4.999999999999999e-32  Rhodopseudomonas palustris BisB5  Bacteria  normal  0.198934  normal  0.328694 
 
 
-
 
NC_013739  Cwoe_3981  binding-protein-dependent transport systems inner membrane component  32.03 
 
 
274 aa  139  4.999999999999999e-32  Conexibacter woesei DSM 14684  Bacteria  normal  0.270796  normal 
 
 
-
 
NC_010003  Pmob_0525  binding-protein-dependent transport systems inner membrane component  28.68 
 
 
282 aa  139  4.999999999999999e-32  Petrotoga mobilis SJ95  Bacteria  normal  0.641488  n/a   
 
 
-
 
NC_013171  Apre_0063  binding-protein-dependent transport systems inner membrane component  25.48 
 
 
291 aa  139  7e-32  Anaerococcus prevotii DSM 20548  Bacteria  normal  n/a   
 
 
-
 
NC_010320  Teth514_1101  binding-protein-dependent transport systems inner membrane component  29.12 
 
 
280 aa  139  7e-32  Thermoanaerobacter sp. X514  Bacteria  normal  n/a   
 
 
-
 
NC_008541  Arth_2947  binding-protein-dependent transport systems inner membrane component  36.32 
 
 
284 aa  137  1e-31  Arthrobacter sp. FB24  Bacteria  normal  n/a   
 
 
-
 
NC_008541  Arth_3322  binding-protein-dependent transport systems inner membrane component  30.14 
 
 
309 aa  138  1e-31  Arthrobacter sp. FB24  Bacteria  normal  0.0903437  n/a   
 
 
-
 
NC_013521  Sked_05240  carbohydrate ABC transporter membrane protein  30.74 
 
 
312 aa  138  1e-31  Sanguibacter keddieii DSM 10542  Bacteria  normal  normal 
 
 
-
 
NC_011004  Rpal_0130  binding-protein-dependent transport systems inner membrane component  29.32 
 
 
278 aa  137  2e-31  Rhodopseudomonas palustris TIE-1  Bacteria  normal  0.519096  n/a   
 
 
-
 
NC_013947  Snas_0205  binding-protein-dependent transport systems inner membrane component  29.14 
 
 
279 aa  137  2e-31  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  0.67338  normal  0.16615 
 
 
-
 
NC_010816  BLD_1550  MalG-type ABC sugar transport system permease component  30.83 
 
 
308 aa  137  2e-31  Bifidobacterium longum DJO10A  Bacteria  normal  n/a   
 
 
-
 
NC_008786  Veis_3455  binding-protein-dependent transport systems inner membrane component  33.47 
 
 
277 aa  137  2e-31  Verminephrobacter eiseniae EF01-2  Bacteria  normal  0.603353  normal 
 
 
-
 
NC_012669  Bcav_1657  binding-protein-dependent transport systems inner membrane component  32.51 
 
 
284 aa  137  2e-31  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.354053  normal  0.174244 
 
 
-
 
NC_010003  Pmob_0719  binding-protein-dependent transport systems inner membrane component  29.01 
 
 
279 aa  137  2e-31  Petrotoga mobilis SJ95  Bacteria  normal  n/a   
 
 
-
 
NC_013411  GYMC61_1729  binding-protein-dependent transport systems inner membrane component  32.2 
 
 
275 aa  136  3.0000000000000003e-31  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_011884  Cyan7425_4081  binding-protein-dependent transport systems inner membrane component  35.71 
 
 
275 aa  136  3.0000000000000003e-31  Cyanothece sp. PCC 7425  Bacteria  normal  normal 
 
 
-
 
NC_013411  GYMC61_2846  binding-protein-dependent transport systems inner membrane component  34.09 
 
 
270 aa  136  4e-31  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_011368  Rleg2_5335  binding-protein-dependent transport systems inner membrane component  31.29 
 
 
278 aa  136  4e-31  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  0.716321  normal 
 
 
-
 
NC_009667  Oant_2483  binding-protein-dependent transport systems inner membrane component  28.96 
 
 
283 aa  136  4e-31  Ochrobactrum anthropi ATCC 49188  Bacteria  normal  0.0788706  n/a   
 
 
-
 
NC_013521  Sked_03070  carbohydrate ABC transporter membrane protein  33.08 
 
 
296 aa  136  4e-31  Sanguibacter keddieii DSM 10542  Bacteria  normal  0.386443  normal 
 
 
-
 
NC_012669  Bcav_2265  binding-protein-dependent transport systems inner membrane component  35.16 
 
 
298 aa  136  5e-31  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.15321  normal 
 
 
-
 
NC_012669  Bcav_3989  binding-protein-dependent transport systems inner membrane component  30.94 
 
 
324 aa  135  5e-31  Beutenbergia cavernae DSM 12333  Bacteria  normal  normal 
 
 
-
 
NC_010003  Pmob_0287  binding-protein-dependent transport systems inner membrane component  29.39 
 
 
279 aa  136  5e-31  Petrotoga mobilis SJ95  Bacteria  normal  0.0553602  n/a   
 
 
-
 
NC_013526  Tter_2616  binding-protein-dependent transport systems inner membrane component  32.4 
 
 
294 aa  135  7.000000000000001e-31  Thermobaculum terrenum ATCC BAA-798  Bacteria  hitchhiker  0.000583333  n/a   
 
 
-
 
NC_008709  Ping_2510  ABC sugar transporter inner membrane binding protein  32.44 
 
 
278 aa  135  7.000000000000001e-31  Psychromonas ingrahamii 37  Bacteria  normal  normal  0.686515 
 
 
-
 
NC_012669  Bcav_3791  binding-protein-dependent transport systems inner membrane component  32.1 
 
 
300 aa  135  7.000000000000001e-31  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.17142  normal 
 
 
-
 
NC_007333  Tfu_1703  putative transport system permease ABC transporter protein  31.09 
 
 
292 aa  135  9.999999999999999e-31  Thermobifida fusca YX  Bacteria  normal  0.757038  n/a   
 
 
-
 
NC_009664  Krad_2231  binding-protein-dependent transport systems inner membrane component  29.39 
 
 
297 aa  135  9.999999999999999e-31  Kineococcus radiotolerans SRS30216  Bacteria  normal  normal  0.807172 
 
 
-
 
NC_009939  Dgeo_2917  ABC-type sugar transport system, permease component  33.84 
 
 
273 aa  135  9.999999999999999e-31  Deinococcus geothermalis DSM 11300  Bacteria  n/a    n/a   
 
 
-
 
NC_003909  BCE_0631  glycerol-3-phosphate ABC transporter, permease protein, putative  27.86 
 
 
273 aa  134  1.9999999999999998e-30  Bacillus cereus ATCC 10987  Bacteria  normal  n/a   
 
 
-
 
NC_012848  Rleg_5052  binding-protein-dependent transport systems inner membrane component  31.48 
 
 
278 aa  134  1.9999999999999998e-30  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  0.482027  normal 
 
 
-
 
NC_011898  Ccel_0202  binding-protein-dependent transport systems inner membrane component  28.79 
 
 
284 aa  134  1.9999999999999998e-30  Clostridium cellulolyticum H10  Bacteria  normal  n/a   
 
 
-
 
NC_014213  Mesil_3228  binding-protein-dependent transport systems inner membrane component  32.21 
 
 
272 aa  134  1.9999999999999998e-30  Meiothermus silvanus DSM 9946  Bacteria  decreased coverage  0.00685083  normal 
 
 
-
 
NC_012669  Bcav_1507  binding-protein-dependent transport systems inner membrane component  29.96 
 
 
303 aa  134  1.9999999999999998e-30  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.659062  normal 
 
 
-
 
NC_010577  XfasM23_1548  monosaccharide-transporting ATPase  33.92 
 
 
278 aa  134  1.9999999999999998e-30  Xylella fastidiosa M23  Bacteria  normal  n/a   
 
 
-
 
NC_014213  Mesil_3420  proteophosphoglycan ppg4  32.21 
 
 
272 aa  134  1.9999999999999998e-30  Meiothermus silvanus DSM 9946  Bacteria  normal  0.257772  normal 
 
 
-
 
NC_009486  Tpet_0320  monosaccharide-transporting ATPase  31.84 
 
 
701 aa  134  1.9999999999999998e-30  Thermotoga petrophila RKU-1  Bacteria  normal  n/a   
 
 
-
 
NC_013947  Snas_3123  binding-protein-dependent transport systems inner membrane component  30.86 
 
 
274 aa  134  1.9999999999999998e-30  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  0.610741  hitchhiker  0.000350702 
 
 
-
 
NC_012669  Bcav_1524  binding-protein-dependent transport systems inner membrane component  32 
 
 
298 aa  134  1.9999999999999998e-30  Beutenbergia cavernae DSM 12333  Bacteria  normal  normal 
 
 
-
 
NC_011886  Achl_3122  binding-protein-dependent transport systems inner membrane component  28.52 
 
 
305 aa  134  1.9999999999999998e-30  Arthrobacter chlorophenolicus A6  Bacteria  n/a    normal  0.290341 
 
 
-
 
NC_010184  BcerKBAB4_0482  binding-protein-dependent transport systems inner membrane component  27.86 
 
 
273 aa  134  1.9999999999999998e-30  Bacillus weihenstephanensis KBAB4  Bacteria  normal  n/a   
 
 
-
 
NC_011658  BCAH187_A0699  putative glycerol-3-phosphate ABC transporter, permease protein  27.86 
 
 
273 aa  134  1.9999999999999998e-30  Bacillus cereus AH187  Bacteria  normal  n/a   
 
 
-
 
NC_013172  Bfae_29710  carbohydrate ABC transporter membrane protein  29.55 
 
 
304 aa  133  3e-30  Brachybacterium faecium DSM 4810  Bacteria  normal  0.942295  n/a   
 
 
-
 
NC_007604  Synpcc7942_0471  ABC-type sugar transport system permease component-like  31.91 
 
 
276 aa  133  3.9999999999999996e-30  Synechococcus elongatus PCC 7942  Bacteria  normal  normal 
 
 
-
 
NC_011772  BCG9842_B4734  putative glycerol-3-phosphate ABC transporter, permease protein  27.48 
 
 
273 aa  133  3.9999999999999996e-30  Bacillus cereus G9842  Bacteria  normal  normal 
 
 
-
 
NC_013739  Cwoe_3955  binding-protein-dependent transport systems inner membrane component  34.43 
 
 
274 aa  133  3.9999999999999996e-30  Conexibacter woesei DSM 14684  Bacteria  normal  normal 
 
 
-
 
NC_005957  BT9727_0479  glycerol-3-phosphate ABC transporter, permease  27.86 
 
 
273 aa  132  5e-30  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  normal  n/a   
 
 
-
 
NC_006274  BCZK0481  glycerol-3-phosphate ABC transporter, permease  27.86 
 
 
273 aa  132  5e-30  Bacillus cereus E33L  Bacteria  normal  n/a   
 
 
-
 
NC_011725  BCB4264_A0605  putative glycerol-3-phosphate ABC transporter, permease protein  27.48 
 
 
273 aa  132  5e-30  Bacillus cereus B4264  Bacteria  normal  n/a   
 
 
-
 
NC_011773  BCAH820_0624  putative glycerol-3-phosphate ABC transporter, permease protein  27.86 
 
 
273 aa  132  5e-30  Bacillus cereus AH820  Bacteria  n/a    normal 
 
 
-
 
NC_013745  Htur_4490  binding-protein-dependent transport systems inner membrane component  33.46 
 
 
287 aa  132  5e-30  Haloterrigena turkmenica DSM 5511  Archaea  normal  0.091777  n/a   
 
 
-
 
NC_005945  BAS0537  glycerol-3-phosphate ABC transporter permease  27.86 
 
 
273 aa  132  6e-30  Bacillus anthracis str. Sterne  Bacteria  normal  n/a   
 
 
-
 
NC_007530  GBAA_0568  glycerol-3-phosphate ABC transporter permease protein  27.86 
 
 
273 aa  132  6e-30  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  normal  n/a   
 
 
-
 
NC_008048  Sala_0749  binding-protein-dependent transport systems inner membrane component  31.68 
 
 
278 aa  132  6e-30  Sphingopyxis alaskensis RB2256  Bacteria  normal  normal 
 
 
-
 
NC_012034  Athe_2079  binding-protein-dependent transport systems inner membrane component  28.84 
 
 
280 aa  132  6.999999999999999e-30  Anaerocellum thermophilum DSM 6725  Bacteria  normal  0.697078  n/a   
 
 
-
 
NC_009636  Smed_2313  binding-protein-dependent transport systems inner membrane component  27.95 
 
 
280 aa  132  6.999999999999999e-30  Sinorhizobium medicae WSM419  Bacteria  normal  0.0326071  normal  0.242877 
 
 
-
 
NC_007802  Jann_2586  binding-protein-dependent transport systems inner membrane component  27.48 
 
 
294 aa  132  7.999999999999999e-30  Jannaschia sp. CCS1  Bacteria  hitchhiker  0.000948808  normal 
 
 
-
 
NC_010513  Xfasm12_1605  ABC transporter sugar permease  33.48 
 
 
278 aa  132  7.999999999999999e-30  Xylella fastidiosa M12  Bacteria  normal  0.732965  n/a   
 
 
-
 
NC_012912  Dd1591_4134  binding-protein-dependent transport systems inner membrane component  29.52 
 
 
295 aa  132  7.999999999999999e-30  Dickeya zeae Ech1591  Bacteria  normal  n/a   
 
 
-
 
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