More than 300 homologs were found in PanDaTox collection
for query gene Bcav_1611 on replicon NC_012669
Organism: Beutenbergia cavernae DSM 12333



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Replicon accession
Locus tag
Product
% identity
Alignment on query gene
Alignment on homolog gene
Length
Bit score

E-value
Organism name
Kingdom
Plasmid clonability
Plasmid unclonability p-value
Fosmid clonability
Fosmid unclonability p-value
Coverage Plot
PanDaTox homologs
Experimental validation
NC_012669  Bcav_1611  two component transcriptional regulator, LuxR family  100 
 
 		 208 aa  402  1e-111  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.548364  normal  1 
 
 
-
 
NC_014151  Cfla_2290  two component transcriptional regulator, LuxR family  68.97 
 
 		 208 aa  265  2.9999999999999995e-70  Cellulomonas flavigena DSM 20109  Bacteria  decreased coverage  0.00802134  hitchhiker  0.000628596 
 
 
-
 
NC_013174  Jden_1659  two component transcriptional regulator, LuxR family  67.33 
 
 		 207 aa  258  5.0000000000000005e-68  Jonesia denitrificans DSM 20603  Bacteria  normal  0.319135  normal  0.0403017 
 
 
-
 
NC_013521  Sked_11330  response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain  69.12 
 
 		 224 aa  250  1e-65  Sanguibacter keddieii DSM 10542  Bacteria  normal  1  normal  0.0103975 
 
 
-
 
NC_013093  Amir_0097  two component transcriptional regulator, LuxR family  57.07 
 
 		 209 aa  220  1.9999999999999999e-56  Actinosynnema mirum DSM 43827  Bacteria  normal  0.142871  n/a   
 
 
-
 
NC_007333  Tfu_2950  LuxR response regulator receiver  49.06 
 
 		 221 aa  203  2e-51  Thermobifida fusca YX  Bacteria  normal  1  n/a   
 
 
-
 
NC_009953  Sare_1528  two component LuxR family transcriptional regulator  53.81 
 
 		 212 aa  197  1.0000000000000001e-49  Salinispora arenicola CNS-205  Bacteria  normal  0.212037  hitchhiker  0.000165031 
 
 
-
 
NC_013131  Caci_0094  two component transcriptional regulator, LuxR family  51.44 
 
 		 233 aa  196  2.0000000000000003e-49  Catenulispora acidiphila DSM 44928  Bacteria  normal  1  normal  0.0277195 
 
 
-
 
NC_013235  Namu_4738  two component transcriptional regulator, LuxR family  51.72 
 
 		 233 aa  196  3e-49  Nakamurella multipartita DSM 44233  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009380  Strop_1577  response regulator receiver  53.3 
 
 		 212 aa  196  3e-49  Salinispora tropica CNB-440  Bacteria  normal  1  normal  0.967001 
 
 
-
 
NC_013595  Sros_3524  response regulator receiver protein  48.98 
 
 		 214 aa  192  2e-48  Streptosporangium roseum DSM 43021  Bacteria  normal  0.0390864  normal  1 
 
 
-
 
NC_008578  Acel_0518  two component LuxR family transcriptional regulator  52.83 
 
 		 225 aa  193  2e-48  Acidothermus cellulolyticus 11B  Bacteria  normal  1  normal  0.665179 
 
 
-
 
NC_014165  Tbis_3505  LuxR family two component transcriptional regulator  49.49 
 
 		 213 aa  192  3e-48  Thermobispora bispora DSM 43833  Bacteria  normal  0.345096  normal  1 
 
 
-
 
NC_013235  Namu_2003  two component transcriptional regulator, LuxR family  49.24 
 
 		 219 aa  191  5e-48  Nakamurella multipartita DSM 44233  Bacteria  normal  0.183245  hitchhiker  0.00373502 
 
 
-
 
NC_013530  Xcel_0190  two component transcriptional regulator, LuxR family  50 
 
 		 219 aa  190  1e-47  Xylanimonas cellulosilytica DSM 15894  Bacteria  normal  0.146862  n/a   
 
 
-
 
NC_009565  TBFG_13154  two component system transcriptional regulatory protein DevR  49.75 
 
 		 217 aa  190  1e-47  Mycobacterium tuberculosis F11  Bacteria  normal  1  normal  1 
 
 
-
 
NC_013159  Svir_01100  response regulator containing a CheY-like receiver domain protein and an HTH DNA-binding domain protein  50.24 
 
 		 214 aa  189  2e-47  Saccharomonospora viridis DSM 43017  Bacteria  normal  1  normal  1 
 
 
-
 
NC_013159  Svir_22850  response regulator containing a CheY-like receiver domain protein and an HTH DNA-binding domain protein  48.76 
 
 		 239 aa  189  2.9999999999999997e-47  Saccharomonospora viridis DSM 43017  Bacteria  normal  1  normal  0.711047 
 
 
-
 
NC_014210  Ndas_4749  two component transcriptional regulator, LuxR family  47.85 
 
 		 223 aa  188  5e-47  Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009921  Franean1_2449  two component LuxR family transcriptional regulator  47.57 
 
 		 211 aa  186  1e-46  Frankia sp. EAN1pec  Bacteria  normal  1  normal  0.265588 
 
 
-
 
NC_007777  Francci3_1487  two component LuxR family transcriptional regulator  53.47 
 
 		 231 aa  187  1e-46  Frankia sp. CcI3  Bacteria  normal  0.0122618  normal  0.753042 
 
 
-
 
NC_009921  Franean1_4979  two component LuxR family transcriptional regulator  50 
 
 		 231 aa  186  3e-46  Frankia sp. EAN1pec  Bacteria  normal  0.889239  normal  0.507767 
 
 
-
 
NC_009338  Mflv_3847  two component LuxR family transcriptional regulator  47.03 
 
 		 216 aa  185  3e-46  Mycobacterium gilvum PYR-GCK  Bacteria  normal  0.118356  decreased coverage  0.00872558 
 
 
-
 
NC_014158  Tpau_4145  two component transcriptional regulator, LuxR family  49.53 
 
 		 216 aa  184  8e-46  Tsukamurella paurometabola DSM 20162  Bacteria  normal  1  n/a   
 
 
-
 
NC_008146  Mmcs_4126  two component LuxR family transcriptional regulator  46.7 
 
 		 220 aa  183  1.0000000000000001e-45  Mycobacterium sp. MCS  Bacteria  normal  1  n/a   
 
 
-
 
NC_008705  Mkms_4201  two component LuxR family transcriptional regulator  46.7 
 
 		 215 aa  183  1.0000000000000001e-45  Mycobacterium sp. KMS  Bacteria  normal  0.180608  normal  1 
 
 
-
 
NC_009077  Mjls_4357  two component LuxR family transcriptional regulator  46.7 
 
 		 215 aa  183  1.0000000000000001e-45  Mycobacterium sp. JLS  Bacteria  normal  1  normal  0.171113 
 
 
-
 
NC_013510  Tcur_0500  two component transcriptional regulator, LuxR family  46.15 
 
 		 226 aa  183  2.0000000000000003e-45  Thermomonospora curvata DSM 43183  Bacteria  normal  1  n/a   
 
 
-
 
NC_008146  Mmcs_1076  two component LuxR family transcriptional regulator  47.8 
 
 		 228 aa  182  2.0000000000000003e-45  Mycobacterium sp. MCS  Bacteria  normal  1  n/a   
 
 
-
 
NC_008705  Mkms_1092  two component LuxR family transcriptional regulator  47.8 
 
 		 228 aa  182  2.0000000000000003e-45  Mycobacterium sp. KMS  Bacteria  normal  0.123414  normal  0.110897 
 
 
-
 
NC_008726  Mvan_1427  two component LuxR family transcriptional regulator  47.52 
 
 		 212 aa  183  2.0000000000000003e-45  Mycobacterium vanbaalenii PYR-1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009077  Mjls_1103  two component LuxR family transcriptional regulator  47.8 
 
 		 228 aa  182  2.0000000000000003e-45  Mycobacterium sp. JLS  Bacteria  normal  0.191898  normal  1 
 
 
-
 
NC_007777  Francci3_2258  two component LuxR family transcriptional regulator  49 
 
 		 224 aa  182  3e-45  Frankia sp. CcI3  Bacteria  normal  0.124896  normal  0.0124728 
 
 
-
 
NC_013093  Amir_1910  two component transcriptional regulator, LuxR family  46.89 
 
 		 218 aa  182  3e-45  Actinosynnema mirum DSM 43827  Bacteria  normal  1  n/a   
 
 
-
 
NC_007333  Tfu_3035  LuxR response regulator receiver  49.25 
 
 		 223 aa  179  2.9999999999999997e-44  Thermobifida fusca YX  Bacteria  normal  1  n/a   
 
 
-
 
NC_008699  Noca_0992  regulatory protein, LuxR  48.26 
 
 		 218 aa  179  2.9999999999999997e-44  Nocardioides sp. JS614  Bacteria  normal  0.850793  n/a   
 
 
-
 
NC_007777  Francci3_3253  two component LuxR family transcriptional regulator  47.34 
 
 		 213 aa  178  4e-44  Frankia sp. CcI3  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009921  Franean1_4062  two component LuxR family transcriptional regulator  47.8 
 
 		 216 aa  178  7e-44  Frankia sp. EAN1pec  Bacteria  normal  0.0448793  normal  0.300284 
 
 
-
 
NC_008699  Noca_0945  response regulator receiver  49.25 
 
 		 216 aa  177  7e-44  Nocardioides sp. JS614  Bacteria  normal  0.0407172  n/a   
 
 
-
 
NC_009921  Franean1_6933  two component LuxR family transcriptional regulator  47.8 
 
 		 244 aa  177  1e-43  Frankia sp. EAN1pec  Bacteria  normal  1  normal  0.322421 
 
 
-
 
NC_008541  Arth_2136  two component LuxR family transcriptional regulator  46.57 
 
 		 254 aa  176  2e-43  Arthrobacter sp. FB24  Bacteria  normal  0.0553154  n/a   
 
 
-
 
NC_013172  Bfae_18340  response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain  49.28 
 
 		 209 aa  175  4e-43  Brachybacterium faecium DSM 4810  Bacteria  normal  1  n/a   
 
 
-
 
NC_013947  Snas_3097  two component transcriptional regulator, LuxR family  45.71 
 
 		 222 aa  171  5.999999999999999e-42  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  0.472018  normal  0.507317 
 
 
-
 
NC_013124  Afer_1446  two component transcriptional regulator, LuxR family  46.31 
 
 		 223 aa  169  3e-41  Acidimicrobium ferrooxidans DSM 10331  Bacteria  normal  1  n/a   
 
 
-
 
NC_013093  Amir_6098  two component transcriptional regulator, LuxR family  47.14 
 
 		 218 aa  168  6e-41  Actinosynnema mirum DSM 43827  Bacteria  normal  1  n/a   
 
 
-
 
NC_008726  Mvan_2548  two component LuxR family transcriptional regulator  47.03 
 
 		 216 aa  166  2e-40  Mycobacterium vanbaalenii PYR-1  Bacteria  normal  0.971783  normal  1 
 
 
-
 
NC_009921  Franean1_1971  two component LuxR family transcriptional regulator  46.04 
 
 		 216 aa  166  2.9999999999999998e-40  Frankia sp. EAN1pec  Bacteria  normal  0.356635  normal  0.773651 
 
 
-
 
NC_013757  Gobs_4820  two component transcriptional regulator, LuxR family  50 
 
 		 218 aa  165  5e-40  Geodermatophilus obscurus DSM 43160  Bacteria  normal  1  n/a   
 
 
-
 
NC_011886  Achl_2073  two component transcriptional regulator, LuxR family  42.36 
 
 		 226 aa  162  3e-39  Arthrobacter chlorophenolicus A6  Bacteria  n/a    hitchhiker  0.00000000764485 
 
 
-
 
NC_013441  Gbro_2140  response regulator receiver  46.23 
 
 		 218 aa  153  2e-36  Gordonia bronchialis DSM 43247  Bacteria  normal  0.95288  n/a   
 
 
-
 
NC_008148  Rxyl_2809  two component LuxR family transcriptional regulator  44.5 
 
 		 219 aa  151  7e-36  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  1  n/a   
 
 
-
 
NC_014212  Mesil_0065  two component transcriptional regulator, LuxR family  38.22 
 
 		 204 aa  141  8e-33  Meiothermus silvanus DSM 9946  Bacteria  normal  1  normal  1 
 
 
-
 
NC_012669  Bcav_2188  two component transcriptional regulator, LuxR family  42.58 
 
 		 220 aa  140  1.9999999999999998e-32  Beutenbergia cavernae DSM 12333  Bacteria  normal  0.546074  normal  1 
 
 
-
 
NC_011831  Cagg_0340  two component transcriptional regulator, LuxR family  37.8 
 
 		 217 aa  138  3.9999999999999997e-32  Chloroflexus aggregans DSM 9485  Bacteria  hitchhiker  0.00614189  hitchhiker  0.00317709 
 
 
-
 
NC_008025  Dgeo_0555  two component LuxR family transcriptional regulator  38.42 
 
 		 228 aa  137  1e-31  Deinococcus geothermalis DSM 11300  Bacteria  normal  1  normal  1 
 
 
-
 
NC_013947  Snas_1903  two component transcriptional regulator, LuxR family  41.59 
 
 		 225 aa  137  1e-31  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  0.202425  normal  0.182857 
 
 
-
 
NC_011772  BCG9842_B3849  DNA-binding response regulator  38.69 
 
 		 210 aa  136  2e-31  Bacillus cereus G9842  Bacteria  decreased coverage  0.0000000308683  hitchhiker  0.000000000350245 
 
 
-
 
NC_008578  Acel_0973  two component LuxR family transcriptional regulator  39.41 
 
 		 216 aa  136  2e-31  Acidothermus cellulolyticus 11B  Bacteria  normal  0.255067  normal  0.404517 
 
 
-
 
NC_009767  Rcas_3262  two component LuxR family transcriptional regulator  37.02 
 
 		 222 aa  136  3.0000000000000003e-31  Roseiflexus castenholzii DSM 13941  Bacteria  normal  1  normal  0.764026 
 
 
-
 
NC_003909  BCE_1563  DNA-binding response regulator  38.69 
 
 		 210 aa  135  3.0000000000000003e-31  Bacillus cereus ATCC 10987  Bacteria  hitchhiker  0.0000000942452  n/a   
 
 
-
 
NC_005945  BAS1348  DNA-binding response regulator  38.69 
 
 		 210 aa  135  3.0000000000000003e-31  Bacillus anthracis str. Sterne  Bacteria  hitchhiker  0.0000440829  n/a   
 
 
-
 
NC_005957  BT9727_1322  response regulator  38.69 
 
 		 210 aa  135  3.0000000000000003e-31  Bacillus thuringiensis serovar konkukian str. 97-27  Bacteria  decreased coverage  7.30192e-17  n/a   
 
 
-
 
NC_013530  Xcel_3326  two component transcriptional regulator, LuxR family  41.01 
 
 		 223 aa  136  3.0000000000000003e-31  Xylanimonas cellulosilytica DSM 15894  Bacteria  normal  1  n/a   
 
 
-
 
NC_007530  GBAA_1457  DNA-binding response regulator  38.69 
 
 		 210 aa  135  3.0000000000000003e-31  Bacillus anthracis str. 'Ames Ancestor'  Bacteria  hitchhiker  0.0000538049  n/a   
 
 
-
 
NC_011658  BCAH187_A1601  DNA-binding response regulator  38.69 
 
 		 210 aa  135  3.0000000000000003e-31  Bacillus cereus AH187  Bacteria  unclonable  0.00000000136266  n/a   
 
 
-
 
NC_013530  Xcel_0239  two component transcriptional regulator, LuxR family  43 
 
 		 230 aa  135  3.0000000000000003e-31  Xylanimonas cellulosilytica DSM 15894  Bacteria  normal  1  n/a   
 
 
-
 
NC_010184  BcerKBAB4_1363  two component LuxR family transcriptional regulator  38.69 
 
 		 210 aa  135  3.0000000000000003e-31  Bacillus weihenstephanensis KBAB4  Bacteria  hitchhiker  0.0039551  n/a   
 
 
-
 
NC_013235  Namu_5018  two component transcriptional regulator, LuxR family  39.6 
 
 		 209 aa  135  4e-31  Nakamurella multipartita DSM 44233  Bacteria  normal  1  normal  1 
 
 
-
 
NC_013159  Svir_38420  response regulator containing a CheY-like receiver domain protein and an HTH DNA-binding domain protein  42 
 
 		 226 aa  135  6.0000000000000005e-31  Saccharomonospora viridis DSM 43017  Bacteria  normal  1  normal  1 
 
 
-
 
NC_011725  BCB4264_A1495  DNA-binding response regulator  38.5 
 
 		 210 aa  134  7.000000000000001e-31  Bacillus cereus B4264  Bacteria  unclonable  0.0000174821  n/a   
 
 
-
 
NC_009972  Haur_4485  two component LuxR family transcriptional regulator  37.56 
 
 		 213 aa  134  7.000000000000001e-31  Herpetosiphon aurantiacus ATCC 23779  Bacteria  normal  0.310872  n/a   
 
 
-
 
NC_009972  Haur_3654  two component LuxR family transcriptional regulator  40.29 
 
 		 221 aa  134  7.000000000000001e-31  Herpetosiphon aurantiacus ATCC 23779  Bacteria  hitchhiker  0.0000210563  n/a   
 
 
-
 
NC_010571  Oter_1700  two component LuxR family transcriptional regulator  36.95 
 
 		 213 aa  134  8e-31  Opitutus terrae PB90-1  Bacteria  normal  1  normal  0.226192 
 
 
-
 
NC_008699  Noca_2943  two component LuxR family transcriptional regulator  38.86 
 
 		 215 aa  134  8e-31  Nocardioides sp. JS614  Bacteria  normal  1  n/a   
 
 
-
 
NC_006274  BCZK1321  response regulator  38.69 
 
 		 210 aa  134  9e-31  Bacillus cereus E33L  Bacteria  hitchhiker  0.00000332221  n/a   
 
 
-
 
NC_011773  BCAH820_1531  DNA-binding response regulator  38.19 
 
 		 210 aa  134  9.999999999999999e-31  Bacillus cereus AH820  Bacteria  n/a    hitchhiker  8.64189e-24 
 
 
-
 
NC_013947  Snas_5788  two component transcriptional regulator, LuxR family  39.13 
 
 		 214 aa  134  9.999999999999999e-31  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  1  normal  0.785726 
 
 
-
 
NC_013411  GYMC61_3240  two component transcriptional regulator, LuxR family  37.26 
 
 		 224 aa  133  9.999999999999999e-31  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_013595  Sros_5304  response regulator receiver protein  44.44 
 
 		 220 aa  133  1.9999999999999998e-30  Streptosporangium roseum DSM 43021  Bacteria  normal  0.128918  normal  1 
 
 
-
 
NC_009674  Bcer98_1160  two component LuxR family transcriptional regulator  38 
 
 		 210 aa  133  1.9999999999999998e-30  Bacillus cytotoxicus NVH 391-98  Bacteria  normal  1  n/a   
 
 
-
 
NC_008578  Acel_1760  two component LuxR family transcriptional regulator  37.98 
 
 		 303 aa  133  1.9999999999999998e-30  Acidothermus cellulolyticus 11B  Bacteria  normal  1  normal  0.887336 
 
 
-
 
NC_011831  Cagg_3359  two component transcriptional regulator, LuxR family  40.28 
 
 		 219 aa  133  1.9999999999999998e-30  Chloroflexus aggregans DSM 9485  Bacteria  hitchhiker  0.00321115  hitchhiker  0.000132937 
 
 
-
 
NC_013757  Gobs_2145  two component transcriptional regulator, LuxR family  39.8 
 
 		 220 aa  132  3e-30  Geodermatophilus obscurus DSM 43160  Bacteria  normal  0.0196231  n/a   
 
 
-
 
NC_008010  Dgeo_2486  two component LuxR family transcriptional regulator  38.61 
 
 		 208 aa  132  3e-30  Deinococcus geothermalis DSM 11300  Bacteria  normal  1  n/a   
 
 
-
 
NC_008740  Maqu_3089  two component LuxR family transcriptional regulator  32.52 
 
 		 219 aa  132  3e-30  Marinobacter aquaeolei VT8  Bacteria  normal  1  n/a   
 
 
-
 
NC_013235  Namu_0523  two component transcriptional regulator, LuxR family  39.9 
 
 		 230 aa  132  3.9999999999999996e-30  Nakamurella multipartita DSM 44233  Bacteria  normal  1  normal  1 
 
 
-
 
NC_010718  Nther_0692  two component transcriptional regulator, LuxR family  33.66 
 
 		 213 aa  132  3.9999999999999996e-30  Natranaerobius thermophilus JW/NM-WN-LF  Bacteria  normal  1  normal  1 
 
 
-
 
NC_007333  Tfu_2491  LuxR response regulator receiver  37.32 
 
 		 242 aa  132  5e-30  Thermobifida fusca YX  Bacteria  normal  0.470277  n/a   
 
 
-
 
NC_009523  RoseRS_4258  two component LuxR family transcriptional regulator  39.5 
 
 		 216 aa  131  6e-30  Roseiflexus sp. RS-1  Bacteria  normal  1  normal  1 
 
 
-
 
NC_009012  Cthe_1267  two component LuxR family transcriptional regulator  34.29 
 
 		 216 aa  131  6.999999999999999e-30  Clostridium thermocellum ATCC 27405  Bacteria  normal  1  n/a   
 
 
-
 
NC_011884  Cyan7425_1401  two component transcriptional regulator, LuxR family  34.15 
 
 		 217 aa  131  7.999999999999999e-30  Cyanothece sp. PCC 7425  Bacteria  normal  1  normal  0.482316 
 
 
-
 
NC_011831  Cagg_1346  two component transcriptional regulator, LuxR family  36.36 
 
 		 236 aa  131  7.999999999999999e-30  Chloroflexus aggregans DSM 9485  Bacteria  normal  0.361751  hitchhiker  0.00000337078 
 
 
-
 
NC_013093  Amir_6235  two component transcriptional regulator, LuxR family  41.87 
 
 		 215 aa  130  1.0000000000000001e-29  Actinosynnema mirum DSM 43827  Bacteria  normal  0.502704  n/a   
 
 
-
 
NC_013947  Snas_3745  two component transcriptional regulator, LuxR family  38.07 
 
 		 235 aa  130  1.0000000000000001e-29  Stackebrandtia nassauensis DSM 44728  Bacteria  normal  0.627677  normal  0.255424 
 
 
-
 
NC_013441  Gbro_3238  regulatory protein LuxR  39.64 
 
 		 228 aa  130  2.0000000000000002e-29  Gordonia bronchialis DSM 43247  Bacteria  normal  1  n/a   
 
 
-
 
NC_013411  GYMC61_1316  two component transcriptional regulator, LuxR family  37 
 
 		 210 aa  130  2.0000000000000002e-29  Geobacillus sp. Y412MC61  Bacteria  n/a    n/a   
 
 
-
 
NC_008148  Rxyl_1550  two component LuxR family transcriptional regulator  36.23 
 
 		 220 aa  130  2.0000000000000002e-29  Rubrobacter xylanophilus DSM 9941  Bacteria  normal  1  n/a   
 
 
-
 
NC_013595  Sros_3331  response regulator receiver protein  39 
 
 		 227 aa  130  2.0000000000000002e-29  Streptosporangium roseum DSM 43021  Bacteria  normal  0.832029  normal  0.250763 
 
 
-
 
NC_011725  BCB4264_A5535  DNA-binding response regulator  35.58 
 
 		 215 aa  130  2.0000000000000002e-29  Bacillus cereus B4264  Bacteria  normal  1  n/a   
 
 
-
 
NC_009523  RoseRS_0938  two component LuxR family transcriptional regulator  37.91 
 
 		 242 aa  129  3e-29  Roseiflexus sp. RS-1  Bacteria  normal  1  normal  1 
 
 
-
 
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