More than 300 homologs were found in PanDaTox collection
for query gene B21_01874 on replicon NC_012892
Organism: Escherichia coli BL21



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
CP001509  ECD_01884  predicted DNA-binding response regulator in two-component system with YedV  100 
 
 
223 aa  451  1.0000000000000001e-126  Escherichia coli BL21(DE3)  Bacteria  unclonable  0.000000533293  n/a   
 
 
-
 
CP001637  EcDH1_1682  two component heavy metal response transcriptional regulator, winged helix family  99.55 
 
 
260 aa  450  1.0000000000000001e-126  Escherichia coli DH1  Bacteria  decreased coverage  0.000000000000361446  n/a   
 
 
-
 
NC_011353  ECH74115_2748  transcriptional regulatory protein YedW  100 
 
 
233 aa  450  1.0000000000000001e-126  Escherichia coli O157:H7 str. EC4115  Bacteria  hitchhiker  0.00000892088  normal  0.227347 
 
 
-
 
NC_012892  B21_01874  hypothetical protein  100 
 
 
223 aa  451  1.0000000000000001e-126  Escherichia coli BL21  Bacteria  unclonable  0.00000061937  n/a   
 
 
-
 
NC_010468  EcolC_1676  transcriptional regulatory protein YedW  100 
 
 
260 aa  452  1.0000000000000001e-126  Escherichia coli ATCC 8739  Bacteria  decreased coverage  0.000000350308  normal  0.20506 
 
 
-
 
NC_009800  EcHS_A2070  transcriptional regulatory protein YedW  100 
 
 
260 aa  452  1.0000000000000001e-126  Escherichia coli HS  Bacteria  hitchhiker  3.15395e-18  n/a   
 
 
-
 
NC_009801  EcE24377A_2200  transcriptional regulatory protein YedW  100 
 
 
260 aa  452  1.0000000000000001e-126  Escherichia coli E24377A  Bacteria  decreased coverage  0.0000000000454941  n/a   
 
 
-
 
NC_010658  SbBS512_E0914  transcriptional regulatory protein YedW  100 
 
 
260 aa  452  1.0000000000000001e-126  Shigella boydii CDC 3083-94  Bacteria  decreased coverage  0.0000000013212  n/a   
 
 
-
 
NC_010498  EcSMS35_1216  transcriptional regulatory protein YedW  100 
 
 
260 aa  452  1.0000000000000001e-126  Escherichia coli SMS-3-5  Bacteria  decreased coverage  0.000000203871  normal  0.637592 
 
 
-
 
NC_011149  SeAg_B1055  transcriptional regulatory protein YedW  75.91 
 
 
226 aa  351  5.9999999999999994e-96  Salmonella enterica subsp. enterica serovar Agona str. SL483  Bacteria  normal  n/a   
 
 
-
 
NC_011094  SeSA_A1160  transcriptional regulatory protein YedW  75.91 
 
 
226 aa  351  5.9999999999999994e-96  Salmonella enterica subsp. enterica serovar Schwarzengrund str. CVM19633  Bacteria  normal  normal  0.728212 
 
 
-
 
NC_011205  SeD_A1171  transcriptional regulatory protein YedW  75.45 
 
 
226 aa  350  1e-95  Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853  Bacteria  normal  normal 
 
 
-
 
NC_011080  SNSL254_A1191  transcriptional regulatory protein YedW  75.91 
 
 
226 aa  350  1e-95  Salmonella enterica subsp. enterica serovar Newport str. SL254  Bacteria  normal  normal 
 
 
-
 
NC_011662  Tmz1t_3985  two component heavy metal response transcriptional regulator, winged helix family  57.59 
 
 
226 aa  259  2e-68  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_011662  Tmz1t_4055  two component heavy metal response transcriptional regulator, winged helix family  56.7 
 
 
226 aa  258  7e-68  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_007971  Rmet_5978  regulatory protein CzcR  56.22 
 
 
225 aa  256  2e-67  Cupriavidus metallidurans CH34  Bacteria  hitchhiker  0.0000269255  normal  0.0723212 
 
 
-
 
NC_009512  Pput_3584  two component heavy metal response transcriptional regulator  56.62 
 
 
226 aa  256  3e-67  Pseudomonas putida F1  Bacteria  normal  normal 
 
 
-
 
NC_012849  Rpic12D_5099  two component heavy metal response transcriptional regulator, winged helix family  57.53 
 
 
228 aa  254  8e-67  Ralstonia pickettii 12D  Bacteria  normal  normal  0.0773075 
 
 
-
 
NC_010322  PputGB1_1699  two component heavy metal response transcriptional regulator  56.62 
 
 
226 aa  254  9e-67  Pseudomonas putida GB-1  Bacteria  normal  hitchhiker  0.00419772 
 
 
-
 
NC_011901  Tgr7_1208  two component heavy metal response transcriptional regulator, winged helix family  57.66 
 
 
226 aa  253  1.0000000000000001e-66  Thioalkalivibrio sp. HL-EbGR7  Bacteria  normal  n/a   
 
 
-
 
NC_002947  PP_2158  two component heavy metal response transcriptional regulator  56.16 
 
 
226 aa  253  1.0000000000000001e-66  Pseudomonas putida KT2440  Bacteria  normal  0.144347  normal  0.036827 
 
 
-
 
NC_010682  Rpic_1841  two component heavy metal response transcriptional regulator, winged helix family  57.08 
 
 
228 aa  252  2.0000000000000002e-66  Ralstonia pickettii 12J  Bacteria  normal  0.99331  hitchhiker  0.00000222676 
 
 
-
 
NC_010682  Rpic_1760  two component heavy metal response transcriptional regulator, winged helix family  55.3 
 
 
225 aa  253  2.0000000000000002e-66  Ralstonia pickettii 12J  Bacteria  normal  0.133831  normal  0.402692 
 
 
-
 
NC_010682  Rpic_1718  two component heavy metal response transcriptional regulator, winged helix family  56.05 
 
 
228 aa  253  2.0000000000000002e-66  Ralstonia pickettii 12J  Bacteria  normal  0.348336  normal 
 
 
-
 
NC_012849  Rpic12D_5335  two component heavy metal response transcriptional regulator, winged helix family  56.05 
 
 
228 aa  253  2.0000000000000002e-66  Ralstonia pickettii 12D  Bacteria  normal  0.733276  normal  0.970872 
 
 
-
 
NC_010676  Bphyt_4933  two component heavy metal response transcriptional regulator, winged helix family  55.25 
 
 
223 aa  253  2.0000000000000002e-66  Burkholderia phytofirmans PsJN  Bacteria  normal  0.461594  normal  0.344735 
 
 
-
 
NC_009656  PSPA7_2348  putative two-component response regulator  56.62 
 
 
228 aa  253  2.0000000000000002e-66  Pseudomonas aeruginosa PA7  Bacteria  normal  0.804247  n/a   
 
 
-
 
NC_007298  Daro_2259  two component heavy metal response transcriptional regulator  57.08 
 
 
225 aa  252  3e-66  Dechloromonas aromatica RCB  Bacteria  normal  normal 
 
 
-
 
NC_007952  Bxe_B1748a  hypothetical protein  54.79 
 
 
223 aa  251  5.000000000000001e-66  Burkholderia xenovorans LB400  Bacteria  normal  0.0697031  normal  0.305387 
 
 
-
 
NC_008463  PA14_27810  putative two-component response regulator  56.16 
 
 
226 aa  251  7e-66  Pseudomonas aeruginosa UCBPP-PA14  Bacteria  normal  normal 
 
 
-
 
NC_003296  RSp0489  response regulator for cobalt zinc cadmium resistance transcription regulator protein  53.57 
 
 
224 aa  250  1e-65  Ralstonia solanacearum GMI1000  Bacteria  normal  normal 
 
 
-
 
NC_003296  RSp0655  two component response regulator transcription regulator protein  57.27 
 
 
228 aa  250  1e-65  Ralstonia solanacearum GMI1000  Bacteria  normal  normal  0.81937 
 
 
-
 
NC_010682  Rpic_1780  two component heavy metal response transcriptional regulator, winged helix family  54.71 
 
 
228 aa  249  2e-65  Ralstonia pickettii 12J  Bacteria  normal  0.817023  normal  0.826624 
 
 
-
 
NC_010084  Bmul_2337  two component heavy metal response transcriptional regulator  56.5 
 
 
227 aa  249  2e-65  Burkholderia multivorans ATCC 17616  Bacteria  normal  normal 
 
 
-
 
NC_007908  Rfer_0422  two component heavy metal response transcriptional regulator  57.53 
 
 
227 aa  248  4e-65  Rhodoferax ferrireducens T118  Bacteria  normal  n/a   
 
 
-
 
NC_007492  Pfl01_3855  two component heavy metal response transcriptional regulator  54.79 
 
 
226 aa  248  5e-65  Pseudomonas fluorescens Pf0-1  Bacteria  normal  normal  0.845216 
 
 
-
 
NC_007963  Csal_0102  two component heavy metal response transcriptional regulator  55.3 
 
 
223 aa  248  6e-65  Chromohalobacter salexigens DSM 3043  Bacteria  normal  0.753235  n/a   
 
 
-
 
NC_011138  MADE_00315  probable two component response regulator transcription regulator protein  55 
 
 
227 aa  248  7e-65  Alteromonas macleodii 'Deep ecotype'  Bacteria  normal  n/a   
 
 
-
 
NC_010002  Daci_0451  two component heavy metal response transcriptional regulator  55.16 
 
 
230 aa  247  9e-65  Delftia acidovorans SPH-1  Bacteria  normal  normal 
 
 
-
 
NC_010681  Bphyt_1510  two component heavy metal response transcriptional regulator, winged helix family  55.3 
 
 
227 aa  246  1e-64  Burkholderia phytofirmans PsJN  Bacteria  normal  normal 
 
 
-
 
NC_010676  Bphyt_5224  two component heavy metal response transcriptional regulator, winged helix family  56.22 
 
 
225 aa  246  2e-64  Burkholderia phytofirmans PsJN  Bacteria  normal  0.57611  normal 
 
 
-
 
NC_007952  Bxe_B1389  two component heavy metal response transcriptional regulator  56.68 
 
 
225 aa  246  2e-64  Burkholderia xenovorans LB400  Bacteria  normal  0.717226  normal  0.091392 
 
 
-
 
NC_007951  Bxe_A2960  two component heavy metal response transcriptional regulator  55.3 
 
 
227 aa  245  3e-64  Burkholderia xenovorans LB400  Bacteria  normal  normal 
 
 
-
 
NC_007973  Rmet_1751  two component heavy metal response transcriptional regulator  55.3 
 
 
224 aa  245  3e-64  Cupriavidus metallidurans CH34  Bacteria  normal  normal  0.0784096 
 
 
-
 
NC_008782  Ajs_2725  two component heavy metal response transcriptional regulator  56.62 
 
 
227 aa  245  3e-64  Acidovorax sp. JS42  Bacteria  normal  normal 
 
 
-
 
NC_008782  Ajs_1236  two component heavy metal response transcriptional regulator  55.25 
 
 
219 aa  245  4e-64  Acidovorax sp. JS42  Bacteria  normal  normal 
 
 
-
 
NC_011992  Dtpsy_2201  two component heavy metal response transcriptional regulator, winged helix family  56.16 
 
 
227 aa  244  4.9999999999999997e-64  Acidovorax ebreus TPSY  Bacteria  normal  n/a   
 
 
-
 
NC_008758  Pnap_4558  two component heavy metal response transcriptional regulator  55.05 
 
 
226 aa  245  4.9999999999999997e-64  Polaromonas naphthalenivorans CJ2  Bacteria  normal  normal 
 
 
-
 
NC_013456  VEA_001641  putative two component response regulator transcription regulator protein  51.79 
 
 
230 aa  244  6.999999999999999e-64  Vibrio sp. Ex25  Bacteria  normal  0.170142  n/a   
 
 
-
 
NC_008782  Ajs_1461  two component heavy metal response transcriptional regulator  56.5 
 
 
227 aa  244  8e-64  Acidovorax sp. JS42  Bacteria  normal  normal 
 
 
-
 
NC_007492  Pfl01_0202  two component heavy metal response transcriptional regulator  52.49 
 
 
226 aa  243  9.999999999999999e-64  Pseudomonas fluorescens Pf0-1  Bacteria  normal  normal 
 
 
-
 
NC_011146  Gbem_3615  two component heavy metal response transcriptional regulator, winged helix family  55.5 
 
 
224 aa  243  9.999999999999999e-64  Geobacter bemidjiensis Bem  Bacteria  normal  n/a   
 
 
-
 
NC_008835  BMA10229_0402  transcriptional activator IrlR  55.3 
 
 
229 aa  243  1.9999999999999999e-63  Burkholderia mallei NCTC 10229  Bacteria  normal  0.0800763  n/a   
 
 
-
 
NC_008784  BMASAVP1_0010  transcriptional activator IrlR  55.3 
 
 
229 aa  243  1.9999999999999999e-63  Burkholderia mallei SAVP1  Bacteria  normal  0.121051  n/a   
 
 
-
 
NC_006349  BMAA1028  DNA-binding response regulator IrlR  55.3 
 
 
229 aa  243  1.9999999999999999e-63  Burkholderia mallei ATCC 23344  Bacteria  normal  0.0282692  n/a   
 
 
-
 
NC_007005  Psyr_3374  heavy metal response regulator  54.84 
 
 
229 aa  243  1.9999999999999999e-63  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  normal 
 
 
-
 
NC_007348  Reut_B3961  heavy metal response regulator  53.46 
 
 
229 aa  243  1.9999999999999999e-63  Ralstonia eutropha JMP134  Bacteria  decreased coverage  0.00889091  n/a   
 
 
-
 
NC_009078  BURPS1106A_A1439  transcriptional activator IrlR  55.3 
 
 
229 aa  243  1.9999999999999999e-63  Burkholderia pseudomallei 1106a  Bacteria  normal  n/a   
 
 
-
 
NC_007435  BURPS1710b_A0030  DNA-binding response regulator IrlR  55.3 
 
 
229 aa  243  1.9999999999999999e-63  Burkholderia pseudomallei 1710b  Bacteria  normal  0.122488  n/a   
 
 
-
 
NC_009079  BMA10247_A1180  transcriptional activator IrlR  55.3 
 
 
229 aa  243  1.9999999999999999e-63  Burkholderia mallei NCTC 10247  Bacteria  normal  0.0831411  n/a   
 
 
-
 
NC_007974  Rmet_5672  DNA-binding response regulator  55.61 
 
 
228 aa  243  1.9999999999999999e-63  Cupriavidus metallidurans CH34  Bacteria  normal  normal 
 
 
-
 
NC_009075  BURPS668_A1524  transcriptional activator protein IrlR  55.3 
 
 
229 aa  243  1.9999999999999999e-63  Burkholderia pseudomallei 668  Bacteria  normal  n/a   
 
 
-
 
NC_010623  Bphy_3962  two component heavy metal response transcriptional regulator  56.68 
 
 
225 aa  242  3e-63  Burkholderia phymatum STM815  Bacteria  normal  normal 
 
 
-
 
NC_007347  Reut_A2490  heavy metal response regulator  56.16 
 
 
228 aa  242  3e-63  Ralstonia eutropha JMP134  Bacteria  normal  0.289616  n/a   
 
 
-
 
NC_008463  PA14_45880  putative two-component response regulator  52.75 
 
 
229 aa  242  3e-63  Pseudomonas aeruginosa UCBPP-PA14  Bacteria  normal  normal  0.954426 
 
 
-
 
NC_010515  Bcenmc03_3842  two component heavy metal response transcriptional regulator  53.39 
 
 
227 aa  242  3.9999999999999997e-63  Burkholderia cenocepacia MC0-3  Bacteria  normal  normal  0.67414 
 
 
-
 
NC_010682  Rpic_1742  two component heavy metal response transcriptional regulator, winged helix family  56.25 
 
 
228 aa  242  3.9999999999999997e-63  Ralstonia pickettii 12J  Bacteria  normal  normal  0.595604 
 
 
-
 
NC_008061  Bcen_4683  two component heavy metal response transcriptional regulator  53.39 
 
 
228 aa  242  3.9999999999999997e-63  Burkholderia cenocepacia AU 1054  Bacteria  normal  0.222547  n/a   
 
 
-
 
NC_008543  Bcen2424_3680  two component heavy metal response transcriptional regulator  53.39 
 
 
228 aa  242  3.9999999999999997e-63  Burkholderia cenocepacia HI2424  Bacteria  normal  0.224842  normal 
 
 
-
 
NC_007511  Bcep18194_B2430  two component heavy metal response transcriptional regulator  53.39 
 
 
227 aa  241  5e-63  Burkholderia sp. 383  Bacteria  normal  normal 
 
 
-
 
NC_007650  BTH_II1376  DNA-binding response regulator IrlR  54.38 
 
 
229 aa  241  7e-63  Burkholderia thailandensis E264  Bacteria  normal  0.498923  n/a   
 
 
-
 
NC_010501  PputW619_0017  two component heavy metal response transcriptional regulator  52.97 
 
 
225 aa  241  9e-63  Pseudomonas putida W619  Bacteria  normal  normal 
 
 
-
 
NC_010322  PputGB1_0019  two component heavy metal response transcriptional regulator  52.97 
 
 
225 aa  241  9e-63  Pseudomonas putida GB-1  Bacteria  normal  0.593373  normal 
 
 
-
 
NC_009512  Pput_0017  two component heavy metal response transcriptional regulator  52.97 
 
 
225 aa  241  9e-63  Pseudomonas putida F1  Bacteria  normal  normal  0.0468746 
 
 
-
 
NC_012791  Vapar_3559  two component heavy metal response transcriptional regulator, winged helix family  53.92 
 
 
225 aa  240  1e-62  Variovorax paradoxus S110  Bacteria  normal  0.710681  n/a   
 
 
-
 
NC_004578  PSPTO_3603  DNA-binding heavy metal response regulator  54.38 
 
 
229 aa  240  1e-62  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  0.203952  n/a   
 
 
-
 
NC_007952  Bxe_B0708  two component heavy metal response transcriptional regulator  54.84 
 
 
226 aa  240  1e-62  Burkholderia xenovorans LB400  Bacteria  normal  0.328024  normal  0.9016 
 
 
-
 
NC_011071  Smal_2165  two component heavy metal response transcriptional regulator, winged helix family  54.71 
 
 
232 aa  240  1e-62  Stenotrophomonas maltophilia R551-3  Bacteria  normal  normal  0.77286 
 
 
-
 
NC_010070  Bmul_6173  two component heavy metal response transcriptional regulator  53.39 
 
 
228 aa  240  1e-62  Burkholderia multivorans ATCC 17616  Bacteria  normal  normal  0.400074 
 
 
-
 
NC_008463  PA14_64570  two-component response regulator  56.22 
 
 
229 aa  240  1e-62  Pseudomonas aeruginosa UCBPP-PA14  Bacteria  normal  normal 
 
 
-
 
NC_007492  Pfl01_4663  two component heavy metal response transcriptional regulator  53.92 
 
 
225 aa  239  2e-62  Pseudomonas fluorescens Pf0-1  Bacteria  normal  0.180214  normal  0.242183 
 
 
-
 
NC_010515  Bcenmc03_4106  two component heavy metal response transcriptional regulator  50.69 
 
 
223 aa  240  2e-62  Burkholderia cenocepacia MC0-3  Bacteria  normal  normal  0.971428 
 
 
-
 
NC_007971  Rmet_6111  regulator protein CopR  55.16 
 
 
228 aa  239  2e-62  Cupriavidus metallidurans CH34  Bacteria  normal  0.110686  normal  0.158568 
 
 
-
 
NC_008061  Bcen_4757  two component heavy metal response transcriptional regulator  50.69 
 
 
223 aa  239  2e-62  Burkholderia cenocepacia AU 1054  Bacteria  normal  0.0878196  n/a   
 
 
-
 
NC_008391  Bamb_5186  two component heavy metal response transcriptional regulator  50.69 
 
 
223 aa  239  2e-62  Burkholderia ambifaria AMMD  Bacteria  normal  normal 
 
 
-
 
NC_010552  BamMC406_3349  two component heavy metal response transcriptional regulator  50.69 
 
 
223 aa  239  2e-62  Burkholderia ambifaria MC40-6  Bacteria  normal  normal 
 
 
-
 
NC_012918  GM21_3720  two component heavy metal response transcriptional regulator, winged helix family  54.59 
 
 
224 aa  239  2e-62  Geobacter sp. M21  Bacteria  n/a    normal 
 
 
-
 
NC_008543  Bcen2424_3410  two component heavy metal response transcriptional regulator  50.69 
 
 
223 aa  239  2e-62  Burkholderia cenocepacia HI2424  Bacteria  normal  normal 
 
 
-
 
NC_002939  GSU2946  DNA-binding heavy metal response regulator  54.95 
 
 
223 aa  239  2.9999999999999997e-62  Geobacter sulfurreducens PCA  Bacteria  normal  n/a   
 
 
-
 
NC_002947  PP_5383  two component heavy metal response transcriptional regulator  53.42 
 
 
225 aa  239  2.9999999999999997e-62  Pseudomonas putida KT2440  Bacteria  normal  normal  0.651671 
 
 
-
 
NC_009656  PSPA7_5607  two-component response regulator  55.76 
 
 
229 aa  239  2.9999999999999997e-62  Pseudomonas aeruginosa PA7  Bacteria  normal  n/a   
 
 
-
 
NC_007347  Reut_A1815  two component heavy metal response transcriptional regulator  54.84 
 
 
224 aa  239  2.9999999999999997e-62  Ralstonia eutropha JMP134  Bacteria  normal  0.275759  n/a   
 
 
-
 
NC_011313  VSAL_II0197  transcriptional activator protein, response regulator  51.79 
 
 
227 aa  239  2.9999999999999997e-62  Aliivibrio salmonicida LFI1238  Bacteria  hitchhiker  0.0086442  n/a   
 
 
-
 
NC_008786  Veis_0344  two component heavy metal response transcriptional regulator  53.92 
 
 
231 aa  238  4e-62  Verminephrobacter eiseniae EF01-2  Bacteria  normal  normal 
 
 
-
 
NC_009708  YpsIP31758_2084  DNA-binding heavy metal response regulator  52.05 
 
 
230 aa  238  4e-62  Yersinia pseudotuberculosis IP 31758  Bacteria  hitchhiker  0.000771382  n/a   
 
 
-
 
NC_007435  BURPS1710b_A1103  DNA-binding response regulator IrlR  53.46 
 
 
230 aa  238  4e-62  Burkholderia pseudomallei 1710b  Bacteria  normal  0.0630149  n/a   
 
 
-
 
NC_009078  BURPS1106A_A2716  DNA-binding heavy metal response regulator  53.46 
 
 
230 aa  238  4e-62  Burkholderia pseudomallei 1106a  Bacteria  normal  0.558922  n/a   
 
 
-
 
NC_009075  BURPS668_A2869  transcriptional activator protein IrlR  53.46 
 
 
230 aa  238  4e-62  Burkholderia pseudomallei 668  Bacteria  normal  0.354021  n/a   
 
 
-
 
NC_009092  Shew_3258  two component heavy metal response transcriptional regulator  52.04 
 
 
238 aa  238  4e-62  Shewanella loihica PV-4  Bacteria  hitchhiker  0.00206307  normal  0.0675777 
 
 
-
 
NC_010465  YPK_2192  two component heavy metal response transcriptional regulator  52.05 
 
 
230 aa  238  5e-62  Yersinia pseudotuberculosis YPIII  Bacteria  normal  n/a   
 
 
-
 
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