More than 300 homologs were found in PanDaTox collection
for query gene Avi_6090 on replicon NC_011988
Organism: Agrobacterium vitis S4



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Replicon accession

Locus tag

Product

% identity

Alignment on query gene

Alignment on homolog gene

Length

Bit score

E-value

Organism name

Kingdom

Plasmid clonability

Plasmid unclonability p-value

Fosmid clonability

Fosmid unclonability p-value

Coverage Plot

PanDaTox homologs

Experimental validation
NC_011988  Avi_6090  ABC transporter membrane spanning protein (polyamine)  100 
 
 
300 aa  580  1.0000000000000001e-165  Agrobacterium vitis S4  Bacteria  normal  0.467049  n/a   
 
 
-
 
NC_009621  Smed_6248  binding-protein-dependent transport systems inner membrane component  82.64 
 
 
291 aa  406  1.0000000000000001e-112  Sinorhizobium medicae WSM419  Bacteria  normal  normal  0.358621 
 
 
-
 
NC_011368  Rleg2_5590  binding-protein-dependent transport systems inner membrane component  74.74 
 
 
290 aa  402  1e-111  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  normal 
 
 
-
 
NC_012854  Rleg_6543  binding-protein-dependent transport systems inner membrane component  75.43 
 
 
290 aa  389  1e-107  Rhizobium leguminosarum bv. trifolii WSM1325  Bacteria  normal  0.548122  normal  0.277874 
 
 
-
 
NC_010087  Bmul_6114  binding-protein-dependent transport systems inner membrane component  62.67 
 
 
294 aa  335  7e-91  Burkholderia multivorans ATCC 17616  Bacteria  normal  0.132934  normal 
 
 
-
 
NC_007434  BURPS1710b_2210  ABC transporter, membrane spanning protein (polyamine)  65.85 
 
 
294 aa  303  3.0000000000000004e-81  Burkholderia pseudomallei 1710b  Bacteria  normal  0.0568314  n/a   
 
 
-
 
NC_009654  Mmwyl1_2485  binding-protein-dependent transport systems inner membrane component  57.56 
 
 
283 aa  285  5.999999999999999e-76  Marinomonas sp. MWYL1  Bacteria  normal  0.0734345  normal 
 
 
-
 
NC_007492  Pfl01_3242  binding-protein dependent transport system inner membrane protein  58.33 
 
 
314 aa  283  3.0000000000000004e-75  Pseudomonas fluorescens Pf0-1  Bacteria  normal  0.549497  normal  0.829711 
 
 
-
 
NC_007005  Psyr_2400  binding-protein dependent transport system inner membrane protein  53.12 
 
 
318 aa  277  1e-73  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  0.0272456  normal  0.898727 
 
 
-
 
NC_004578  PSPTO_2666  spermidine/putrescine ABC transporter, permease protein, putative  54.95 
 
 
284 aa  274  1.0000000000000001e-72  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  0.0393724  n/a   
 
 
-
 
NC_002947  PP_3815  binding-protein-dependent transport systems inner membrane component  52.67 
 
 
305 aa  269  4e-71  Pseudomonas putida KT2440  Bacteria  normal  0.972091  normal  0.192229 
 
 
-
 
NC_010322  PputGB1_2090  binding-protein-dependent transport systems inner membrane component  52.07 
 
 
305 aa  268  5.9999999999999995e-71  Pseudomonas putida GB-1  Bacteria  normal  0.394579  normal 
 
 
-
 
NC_010501  PputW619_1934  binding-protein-dependent transport systems inner membrane component  57.92 
 
 
305 aa  266  4e-70  Pseudomonas putida W619  Bacteria  normal  normal  0.0157506 
 
 
-
 
NC_009439  Pmen_3448  binding-protein-dependent transport systems inner membrane component  59.45 
 
 
298 aa  265  7e-70  Pseudomonas mendocina ymp  Bacteria  normal  normal  0.420206 
 
 
-
 
NC_009512  Pput_1954  binding-protein-dependent transport systems inner membrane component  57.14 
 
 
305 aa  258  7e-68  Pseudomonas putida F1  Bacteria  normal  0.336194  normal  0.870065 
 
 
-
 
NC_014165  Tbis_1589  binding-protein-dependent transporter inner membrane component  42.08 
 
 
303 aa  194  2e-48  Thermobispora bispora DSM 43833  Bacteria  normal  normal  0.0639141 
 
 
-
 
NC_007643  Rru_A2046  binding-protein dependent transport system inner membrane protein  45.91 
 
 
406 aa  184  1.0000000000000001e-45  Rhodospirillum rubrum ATCC 11170  Bacteria  normal  0.480866  n/a   
 
 
-
 
NC_007908  Rfer_0595  binding-protein-dependent transport systems inner membrane component  44.04 
 
 
413 aa  184  1.0000000000000001e-45  Rhodoferax ferrireducens T118  Bacteria  normal  n/a   
 
 
-
 
NC_004311  BRA0328  spermidine/putrescine ABC transporter, permease protein, putative  44.05 
 
 
412 aa  182  8.000000000000001e-45  Brucella suis 1330  Bacteria  normal  n/a   
 
 
-
 
NC_010622  Bphy_2381  binding-protein-dependent transport systems inner membrane component  42.27 
 
 
420 aa  181  9.000000000000001e-45  Burkholderia phymatum STM815  Bacteria  normal  0.916996  normal 
 
 
-
 
NC_012791  Vapar_4698  binding-protein-dependent transport systems inner membrane component  42.65 
 
 
418 aa  181  2e-44  Variovorax paradoxus S110  Bacteria  normal  n/a   
 
 
-
 
NC_010625  Bphy_6579  binding-protein-dependent transport systems inner membrane component  41.74 
 
 
302 aa  179  4.999999999999999e-44  Burkholderia phymatum STM815  Bacteria  normal  0.21378  normal  0.43558 
 
 
-
 
NC_009668  Oant_3715  binding-protein-dependent transport systems inner membrane component  46.26 
 
 
391 aa  178  1e-43  Ochrobactrum anthropi ATCC 49188  Bacteria  normal  n/a   
 
 
-
 
NC_011894  Mnod_3648  binding-protein-dependent transport systems inner membrane component  41.55 
 
 
288 aa  176  5e-43  Methylobacterium nodulans ORS 2060  Bacteria  normal  n/a   
 
 
-
 
NC_008044  TM1040_2989  binding-protein-dependent transport systems inner membrane component  42.2 
 
 
541 aa  175  7e-43  Ruegeria sp. TM1040  Bacteria  normal  0.263811  normal  0.821949 
 
 
-
 
NC_013456  VEA_003667  putative permease of ABC transporter  43.08 
 
 
426 aa  175  7e-43  Vibrio sp. Ex25  Bacteria  normal  n/a   
 
 
-
 
NC_011368  Rleg2_4994  binding-protein-dependent transport systems inner membrane component  38.64 
 
 
290 aa  175  8e-43  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  normal 
 
 
-
 
NC_007952  Bxe_B1508  ABC spermidine/putrescine transporter, inner membrane subunit  38.43 
 
 
301 aa  175  8e-43  Burkholderia xenovorans LB400  Bacteria  normal  0.0734046  normal  0.0460711 
 
 
-
 
NC_012856  Rpic12D_1520  binding-protein-dependent transport systems inner membrane component  42.71 
 
 
422 aa  174  9.999999999999999e-43  Ralstonia pickettii 12D  Bacteria  normal  0.030853  normal  0.984041 
 
 
-
 
NC_010682  Rpic_1469  binding-protein-dependent transport systems inner membrane component  42.19 
 
 
422 aa  173  1.9999999999999998e-42  Ralstonia pickettii 12J  Bacteria  normal  0.633443  hitchhiker  0.0000000331128 
 
 
-
 
NC_010676  Bphyt_6152  binding-protein-dependent transport systems inner membrane component  38.43 
 
 
301 aa  174  1.9999999999999998e-42  Burkholderia phytofirmans PsJN  Bacteria  normal  normal 
 
 
-
 
NC_008686  Pden_2150  binding-protein-dependent transport systems inner membrane component  43.81 
 
 
433 aa  173  1.9999999999999998e-42  Paracoccus denitrificans PD1222  Bacteria  normal  normal 
 
 
-
 
NC_008687  Pden_3461  binding-protein-dependent transport systems inner membrane component  43.81 
 
 
430 aa  173  2.9999999999999996e-42  Paracoccus denitrificans PD1222  Bacteria  normal  0.881992  normal 
 
 
-
 
NC_008254  Meso_1863  binding-protein-dependent transport systems inner membrane component  38.11 
 
 
285 aa  173  2.9999999999999996e-42  Chelativorans sp. BNC1  Bacteria  normal  0.844332  n/a   
 
 
-
 
NC_013510  Tcur_0447  binding-protein-dependent transport systems inner membrane component  39.27 
 
 
301 aa  173  2.9999999999999996e-42  Thermomonospora curvata DSM 43183  Bacteria  normal  n/a   
 
 
-
 
NC_008391  Bamb_4295  binding-protein-dependent transport systems inner membrane component  42.71 
 
 
420 aa  172  3.9999999999999995e-42  Burkholderia ambifaria AMMD  Bacteria  normal  0.193876  normal 
 
 
-
 
NC_004311  BRA1106  polyamine ABC transporter, permease protein, putative  40.18 
 
 
271 aa  172  5e-42  Brucella suis 1330  Bacteria  normal  n/a   
 
 
-
 
NC_007005  Psyr_4613  binding-protein dependent transport system inner membrane protein  40.59 
 
 
415 aa  172  5e-42  Pseudomonas syringae pv. syringae B728a  Bacteria  normal  normal  0.993847 
 
 
-
 
NC_007948  Bpro_2915  binding-protein-dependent transport systems inner membrane component  40.28 
 
 
416 aa  172  5e-42  Polaromonas sp. JS666  Bacteria  normal  0.187641  normal 
 
 
-
 
NC_004578  PSPTO_0564  polyamine ABC transporter, permease protein  40.17 
 
 
415 aa  171  2e-41  Pseudomonas syringae pv. tomato str. DC3000  Bacteria  normal  n/a   
 
 
-
 
NC_008786  Veis_4043  binding-protein-dependent transport systems inner membrane component  43.52 
 
 
527 aa  169  4e-41  Verminephrobacter eiseniae EF01-2  Bacteria  normal  normal 
 
 
-
 
NC_009485  BBta_1612  spermidine/putrescine ABC transporter permease  41.92 
 
 
392 aa  169  4e-41  Bradyrhizobium sp. BTAi1  Bacteria  normal  normal 
 
 
-
 
NC_013421  Pecwa_2542  binding-protein-dependent transport systems inner membrane component  35.46 
 
 
422 aa  169  5e-41  Pectobacterium wasabiae WPP163  Bacteria  normal  0.275923  n/a   
 
 
-
 
NC_012917  PC1_2229  binding-protein-dependent transport systems inner membrane component  34.24 
 
 
422 aa  169  7e-41  Pectobacterium carotovorum subsp. carotovorum PC1  Bacteria  normal  0.838973  n/a   
 
 
-
 
NC_008781  Pnap_2633  binding-protein-dependent transport systems inner membrane component  40.27 
 
 
423 aa  168  8e-41  Polaromonas naphthalenivorans CJ2  Bacteria  normal  0.252621  normal 
 
 
-
 
NC_007511  Bcep18194_B2168  ABC spermidine/putrescine transporter, inner membrane subunit  40.62 
 
 
418 aa  168  9e-41  Burkholderia sp. 383  Bacteria  normal  0.0193763  normal 
 
 
-
 
NC_009439  Pmen_4001  binding-protein-dependent transport systems inner membrane component  41.44 
 
 
415 aa  168  1e-40  Pseudomonas mendocina ymp  Bacteria  normal  normal 
 
 
-
 
NC_010625  Bphy_6037  binding-protein-dependent transport systems inner membrane component  38.64 
 
 
421 aa  168  1e-40  Burkholderia phymatum STM815  Bacteria  normal  0.356927  normal  0.017991 
 
 
-
 
NC_010623  Bphy_4323  binding-protein-dependent transport systems inner membrane component  40 
 
 
423 aa  168  1e-40  Burkholderia phymatum STM815  Bacteria  normal  normal  0.554758 
 
 
-
 
NC_007952  Bxe_B2931  spermidine/putrescine ABC transporter inner membrane protein  39.9 
 
 
422 aa  167  2e-40  Burkholderia xenovorans LB400  Bacteria  normal  normal 
 
 
-
 
NC_010681  Bphyt_2373  binding-protein-dependent transport systems inner membrane component  39.09 
 
 
417 aa  167  2e-40  Burkholderia phytofirmans PsJN  Bacteria  normal  normal 
 
 
-
 
NC_009049  Rsph17029_0532  binding-protein-dependent transport systems inner membrane component  42.66 
 
 
424 aa  166  4e-40  Rhodobacter sphaeroides ATCC 17029  Bacteria  normal  0.686624  normal 
 
 
-
 
NC_009428  Rsph17025_0668  binding-protein-dependent transport systems inner membrane component  41.74 
 
 
424 aa  166  4e-40  Rhodobacter sphaeroides ATCC 17025  Bacteria  normal  decreased coverage  0.00457285 
 
 
-
 
NC_012912  Dd1591_1870  binding-protein-dependent transport systems inner membrane component  40.7 
 
 
423 aa  166  5e-40  Dickeya zeae Ech1591  Bacteria  normal  n/a   
 
 
-
 
NC_007650  BTH_II0644  spermidine/putrescine ABC transporter, permease protein  39.72 
 
 
419 aa  166  5.9999999999999996e-40  Burkholderia thailandensis E264  Bacteria  normal  n/a   
 
 
-
 
NC_007951  Bxe_A3471  ABC spermidine/putrescine transporter, innermembrane subunit  39.09 
 
 
417 aa  166  5.9999999999999996e-40  Burkholderia xenovorans LB400  Bacteria  normal  normal  0.60984 
 
 
-
 
NC_011369  Rleg2_4106  binding-protein-dependent transport systems inner membrane component  43.56 
 
 
389 aa  165  6.9999999999999995e-40  Rhizobium leguminosarum bv. trifolii WSM2304  Bacteria  normal  normal 
 
 
-
 
NC_009079  BMA10247_A0484  spermidine/putrescine ABC transporter, permease protein  39.25 
 
 
419 aa  165  9e-40  Burkholderia mallei NCTC 10247  Bacteria  normal  n/a   
 
 
-
 
NC_008835  BMA10229_1813  spermidine/putrescine ABC transporter, permease protein  39.25 
 
 
419 aa  165  9e-40  Burkholderia mallei NCTC 10229  Bacteria  normal  0.574113  n/a   
 
 
-
 
NC_006349  BMAA0433  spermidine/putrescine ABC transporter, permease protein  39.25 
 
 
419 aa  165  9e-40  Burkholderia mallei ATCC 23344  Bacteria  normal  n/a   
 
 
-
 
NC_007435  BURPS1710b_A0813  spermidine/putrescine ABC transporter, permease protein  39.25 
 
 
419 aa  165  9e-40  Burkholderia pseudomallei 1710b  Bacteria  normal  0.780468  n/a   
 
 
-
 
NC_007493  RSP_1884  ABC polyamine/opine transporter, inner membrane subunit  42.66 
 
 
424 aa  165  9e-40  Rhodobacter sphaeroides 2.4.1  Bacteria  normal  0.343799  n/a   
 
 
-
 
NC_010087  Bmul_5430  binding-protein-dependent transport systems inner membrane component  41.43 
 
 
462 aa  165  9e-40  Burkholderia multivorans ATCC 17616  Bacteria  normal  normal  0.105452 
 
 
-
 
NC_009075  BURPS668_A2499  putative polyamine ABC transporter, permease protein  39.25 
 
 
419 aa  165  9e-40  Burkholderia pseudomallei 668  Bacteria  normal  n/a   
 
 
-
 
NC_009078  BURPS1106A_A2360  putative polyamine ABC transporter, permease protein  39.25 
 
 
419 aa  165  9e-40  Burkholderia pseudomallei 1106a  Bacteria  normal  n/a   
 
 
-
 
NC_013739  Cwoe_4944  binding-protein-dependent transport systems inner membrane component  39.75 
 
 
588 aa  165  9e-40  Conexibacter woesei DSM 14684  Bacteria  normal  0.0237049  normal  0.467133 
 
 
-
 
NC_010086  Bmul_4663  binding-protein-dependent transport systems inner membrane component  41.43 
 
 
446 aa  165  9e-40  Burkholderia multivorans ATCC 17616  Bacteria  normal  0.0108621  normal 
 
 
-
 
NC_011729  PCC7424_3605  binding-protein-dependent transport systems inner membrane component  38.19 
 
 
295 aa  164  1.0000000000000001e-39  Cyanothece sp. PCC 7424  Bacteria  n/a    normal  0.0391464 
 
 
-
 
NC_010501  PputW619_4789  binding-protein-dependent transport systems inner membrane component  39.91 
 
 
415 aa  164  1.0000000000000001e-39  Pseudomonas putida W619  Bacteria  normal  normal  0.966966 
 
 
-
 
NC_008543  Bcen2424_3920  binding-protein-dependent transport systems inner membrane component  40.65 
 
 
418 aa  165  1.0000000000000001e-39  Burkholderia cenocepacia HI2424  Bacteria  normal  normal 
 
 
-
 
NC_011662  Tmz1t_0426  binding-protein-dependent transport systems inner membrane component  40 
 
 
424 aa  165  1.0000000000000001e-39  Thauera sp. MZ1T  Bacteria  normal  n/a   
 
 
-
 
NC_008061  Bcen_4446  binding-protein-dependent transport systems inner membrane component  40.65 
 
 
418 aa  165  1.0000000000000001e-39  Burkholderia cenocepacia AU 1054  Bacteria  normal  0.126385  n/a   
 
 
-
 
NC_009620  Smed_3735  binding-protein-dependent transport systems inner membrane component  36.33 
 
 
283 aa  164  1.0000000000000001e-39  Sinorhizobium medicae WSM419  Bacteria  normal  0.153195  normal 
 
 
-
 
NC_010676  Bphyt_6886  binding-protein-dependent transport systems inner membrane component  39.9 
 
 
425 aa  165  1.0000000000000001e-39  Burkholderia phytofirmans PsJN  Bacteria  normal  0.653272  normal  0.230244 
 
 
-
 
NC_008391  Bamb_3298  binding-protein-dependent transport systems inner membrane component  41.43 
 
 
420 aa  165  1.0000000000000001e-39  Burkholderia ambifaria AMMD  Bacteria  normal  0.753859  normal 
 
 
-
 
NC_010552  BamMC406_3814  binding-protein-dependent transport systems inner membrane component  41.43 
 
 
420 aa  165  1.0000000000000001e-39  Burkholderia ambifaria MC40-6  Bacteria  normal  0.156739  normal 
 
 
-
 
NC_010515  Bcenmc03_3607  binding-protein-dependent transport systems inner membrane component  40.65 
 
 
418 aa  165  1.0000000000000001e-39  Burkholderia cenocepacia MC0-3  Bacteria  normal  normal 
 
 
-
 
NC_011894  Mnod_4262  binding-protein-dependent transport systems inner membrane component  36.76 
 
 
593 aa  164  2.0000000000000002e-39  Methylobacterium nodulans ORS 2060  Bacteria  normal  n/a   
 
 
-
 
NC_010322  PputGB1_0444  binding-protein-dependent transport systems inner membrane component  39.91 
 
 
415 aa  164  2.0000000000000002e-39  Pseudomonas putida GB-1  Bacteria  normal  normal  0.382081 
 
 
-
 
NC_012880  Dd703_1787  binding-protein-dependent transport systems inner membrane component  39.7 
 
 
423 aa  164  2.0000000000000002e-39  Dickeya dadantii Ech703  Bacteria  normal  0.229456  n/a   
 
 
-
 
NC_008312  Tery_2818  binding-protein-dependent transport systems inner membrane component  38.04 
 
 
293 aa  164  2.0000000000000002e-39  Trichodesmium erythraeum IMS101  Bacteria  normal  normal  0.913053 
 
 
-
 
NC_009050  Rsph17029_3638  binding-protein-dependent transport systems inner membrane component  35.96 
 
 
291 aa  163  3e-39  Rhodobacter sphaeroides ATCC 17029  Bacteria  normal  normal  0.50975 
 
 
-
 
NC_009512  Pput_0447  binding-protein-dependent transport systems inner membrane component  39.44 
 
 
415 aa  163  3e-39  Pseudomonas putida F1  Bacteria  normal  normal  0.328312 
 
 
-
 
NC_002947  PP_0413  binding-protein-dependent transport systems inner membrane component  39.44 
 
 
415 aa  163  4.0000000000000004e-39  Pseudomonas putida KT2440  Bacteria  normal  0.155483  normal 
 
 
-
 
NC_007492  Pfl01_5123  binding-protein dependent transport system inner membrane protein  38.49 
 
 
415 aa  163  4.0000000000000004e-39  Pseudomonas fluorescens Pf0-1  Bacteria  normal  0.0230497  normal  0.706395 
 
 
-
 
NC_007643  Rru_A1016  binding-protein dependent transport system inner membrane protein  34.25 
 
 
330 aa  162  5.0000000000000005e-39  Rhodospirillum rubrum ATCC 11170  Bacteria  normal  0.725697  n/a   
 
 
-
 
NC_008786  Veis_2367  binding-protein-dependent transport systems inner membrane component  36.36 
 
 
597 aa  161  2e-38  Verminephrobacter eiseniae EF01-2  Bacteria  normal  normal 
 
 
-
 
NC_009654  Mmwyl1_3521  binding-protein-dependent transport systems inner membrane component  38.16 
 
 
296 aa  160  2e-38  Marinomonas sp. MWYL1  Bacteria  normal  normal  0.248217 
 
 
-
 
NC_009621  Smed_5471  binding-protein-dependent transport systems inner membrane component  39.19 
 
 
588 aa  159  5e-38  Sinorhizobium medicae WSM419  Bacteria  normal  normal 
 
 
-
 
NC_011901  Tgr7_1262  ABC-type spermidine/putrescine transport system  39.15 
 
 
322 aa  158  1e-37  Thioalkalivibrio sp. HL-EbGR7  Bacteria  normal  n/a   
 
 
-
 
NC_010511  M446_3865  binding-protein-dependent transport systems inner membrane component  33.33 
 
 
283 aa  157  1e-37  Methylobacterium sp. 4-46  Bacteria  normal  0.783769  normal 
 
 
-
 
NC_009438  Sputcn32_1096  binding-protein-dependent transport systems inner membrane component  34.75 
 
 
301 aa  157  2e-37  Shewanella putrefaciens CN-32  Bacteria  normal  0.0511337  n/a   
 
 
-
 
NC_008254  Meso_3745  binding-protein-dependent transport systems inner membrane component  33.1 
 
 
299 aa  157  2e-37  Chelativorans sp. BNC1  Bacteria  normal  0.807342  n/a   
 
 
-
 
NC_008321  Shewmr4_2916  binding-protein-dependent transport systems inner membrane component  38.14 
 
 
301 aa  157  2e-37  Shewanella sp. MR-4  Bacteria  hitchhiker  0.0057841  normal  0.437411 
 
 
-
 
NC_008322  Shewmr7_2998  binding-protein-dependent transport systems inner membrane component  38.14 
 
 
301 aa  157  2e-37  Shewanella sp. MR-7  Bacteria  normal  0.0768287  normal 
 
 
-
 
NC_008577  Shewana3_3095  binding-protein-dependent transport systems inner membrane component  37.67 
 
 
301 aa  157  3e-37  Shewanella sp. ANA-3  Bacteria  normal  0.0587247  normal 
 
 
-
 
NC_009708  YpsIP31758_1220  spermidine/putrescine ABC transporter, permease protein  40.2 
 
 
421 aa  156  3e-37  Yersinia pseudotuberculosis IP 31758  Bacteria  normal  n/a   
 
 
-
 
NC_009457  VC0395_A1038  spermidine/putrescine ABC transporter membrane protein  38.64 
 
 
286 aa  156  4e-37  Vibrio cholerae O395  Bacteria  hitchhiker  0.00000000000702638  n/a   
 
 
-
 
NC_007510  Bcep18194_A6347  ABC spermidine/putrescine transporter, inner membrane subunit  33.33 
 
 
328 aa  156  5.0000000000000005e-37  Burkholderia sp. 383  Bacteria  normal  normal 
 
 
-
 
NC_007511  Bcep18194_B2812  ABC spermidine/putrescine transporter, inner membrane subunit  33.01 
 
 
328 aa  155  7e-37  Burkholderia sp. 383  Bacteria  normal  normal 
 
 
-
 
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